METHOD FOR PRODUCING PRESSURE EQUALIZATION AND ASSOCIATED SET

Description

[0001] The present application relates to a set according to the preamble of claim 1. Furthermore, the application relates to a method for producing a pressure equalization according to claim 13.

[0002] The set comprises at least one container and at least one lid for sealing the container. The container itself has an interior space in which a bodily fluid can be stored. This bodily fluid can be, in particular, blood, urine, saliva, or other bodily fluid collected from a patient. Generally, the bodily fluid is intended to be placed in the container after collection and stored there until analysis. The lid of the set ensures secure storage. The set can be switched between a sealed position and a vented position. In the sealed position, the container and lid together form an airtight seal. In other words, the lid is in contact with the container in such a way that air cannot escape.In particular, this also prevents bodily fluids from leaking out of the container. The set is typically moved into the sealed position after the bodily fluids have been removed to ensure safe transport and storage.

[0003] Furthermore, the set includes a sampling unit. This unit allows for the extraction of body fluid from the container's interior, even when the container is in the sealed position, i.e., when the lid is airtight. Typically, the sampling unit is used to extract the required amount of body fluid for analysis. It facilitates this process particularly easily, as removing the lid is unnecessary. The body fluid can be extracted using a sampling device, such as a syringe with or without a needle, which is inserted through the sampling unit into the container's interior to aspirate the fluid.

[0004] If a negative pressure is present inside the container as a result of the removal of body fluid from the container by the sampling unit, the lid and / or the container are deformable by the pressure difference between the interior of the container and the environment, so that the set can be moved from the sealing position to the ventilation position, whereby in the ventilation position of the set air from the environment flows into the interior of the container and ventilates the interior of the container. State of the art

[0005] A set of the type described above is already known in the prior art. In particular, reference is made to the applicant's "V-Monovette Urine". However, known sets for storing body fluids with a dispensing unit for extracting the fluid exhibit the problem that, as a result of extracting the fluid from the container, for example by aspiration with a syringe, a pressure difference develops between the interior of the container and the surrounding environment. This ambient pressure generally corresponds to atmospheric pressure. Once a certain negative pressure is reached, further extraction of the fluid from the container is prevented because the airtight seal between the lid and the container prevents air from flowing into the interior. Air flowing through the dispensing unit is also prevented.To allow further aspiration of body fluids, the container must first be vented. The set must therefore be moved into the venting position. This requires removing the lid of the set from the container to allow air to enter and thus equalize the pressure difference. Since the lid is typically screwed onto the container, this procedure has proven to be cumbersome and time-consuming. Additionally, there is a risk of accidentally spilling body fluids when the container is reopened. Therefore, the removal of body fluids can only be done in portions and is interrupted by manually venting the container.

[0006] US6874656 B2 discloses the preamble of claim 1. Task

[0007] The present application is therefore based on the task of producing a set that enables easy removal of body fluid from the container when the set is in the sealing position. Solution

[0008] The underlying problem is solved according to the invention by means of a set comprising the features of claim 1. Advantageous embodiments are described in the dependent claims.

[0009] The set is characterized in that the lid has at least one ventilation element which, when the set is in the ventilation position, creates at least one gap in the sealing fit between the lid and the container due to the deformation of the lid and / or the container as a result of contact with the container and / or the lid, through which air from the environment can flow into the interior of the container.

[0010] The set according to the invention has many advantages. In particular, the set enables the removal of body fluid from the interior of the container via the removal unit, without the need to remove the lid from the container to equalize pressure. Rather, the set has a self-venting function. In other words, no manual intervention is required to vent the interior of the container. As a result of the removal of body fluid, for example, for further processing and / or examination, the lid and / or the container deform, since the removal process, due to the airtight seal between the lid and the container, creates a pressure difference between the interior of the container and the surrounding environment.In particular, the removal of body fluid from the container causes a decrease in the pressure inside the container, resulting in a negative pressure. This leads to the deformation of the lid and / or the container mentioned earlier.

[0011] It is conceivable that the lid has a substantially flat base and rim, whereby the base deforms due to the negative pressure inside the container, becoming convex. This deformation of the lid and / or container moves the set into the vented position. In this position, air from the surrounding environment can flow in, thus ventilating the container's interior. Once the pressure difference between the interior and the environment is eliminated, the set automatically returns to the sealed position, as the deformation of the lid and / or container was solely due to the pressure difference, which is now eliminated after ventilation. Therefore, air can only flow into the container's interior when the set is in the vented position.In the sealed position, however, this is precisely what is not desired. Advantageously, the set allows any desired amount of bodily fluid to be removed from the container without having to manually ventilate the interior.

[0012] In addition to the sealing and venting positions, the set can have other positions, in particular the position in which the lid is removed from the container. This position can be used to fill the container with bodily fluid. After filling, the set can be moved into the sealing position by bringing the lid into contact with the container, for example, by screwing it on.

[0013] The venting element is preferably pressed against the lid and / or the container as a result of the deformation of the lid and / or the container. For example, it is conceivable that the lid is deformed by the negative pressure in such a way that the base of the lid bulges, with the lid rim also being at least partially deformed due to the deformation of the base, and a deforming area of ​​the lid rim creating the gap in the sealing seat. As the negative pressure inside the container increases, the resulting gap enlarges. Consequently, air from the surroundings can flow into the interior of the container and vent it. As a result of the inflowing air, the pressure difference between the interior and the surroundings is eliminated.Preferably, as a result of ventilation and deformation of the lid and / or the container, the set is returned to a starting position in the sealing position, in which the sealing seat between the lid and the container is present.

[0014] According to a preferred embodiment of the invention, the ventilation element is designed in the form of a cam. Tests have shown that a cam-shaped ventilation element is particularly well-suited to creating a gap in the sealing fit between the lid and the container. The cam can preferably be teardrop-shaped and arranged on the lid of the set such that a wider side of the teardrop-shaped cam comes into contact with the container when the lid is deformed, thus forming the gap.

[0015] According to an advantageous embodiment of the invention, the cam is arranged on the underside of the lid facing the container when the set is in the sealing position. In the sealing position of the set, the lid closes the container, and the underside of the lid preferably faces the interior of the lid. If the lid and / or the container deforms, the distance between the cam and a wall of the container can decrease to such an extent that the cam comes into contact with the wall of the container and, with a further reduction of the distance, forms the gap in the sealing seat. The arrangement of the cam on the underside of the lid has proven particularly advantageous in the event that the lid deforms due to pressure differentials. The cam should be arranged on the underside of the lid such that, in a closed state of the container, i.e.,When the lid is on the container and the set is in the sealing position, it has no contact with the container. Only when a negative pressure exists inside the container should the cam come into contact with the container, particularly its wall, and move the set into the venting position. The negative pressure prevailing in the container, at which deformation of the lid occurs, can be predetermined by the choice of material for the lid and / or the container. In this way, it can be ensured that the lid does not deform even under very low negative pressures. After ambient air flows into the interior of the container, the lid preferably returns to its initial position in which the cam does not come into contact with the container. The set is thus once again in the sealing position.

[0016] A preferred embodiment provides that the sampling unit is tubular, open at one end and equipped at the other end with a self-sealing membrane that closes upon and after piercing. Preferably, the body fluid is extracted from the container using a sampling device, for example, a syringe, which may also include a cannula. A tubular design of the sampling unit is particularly advantageous because the syringe, especially when used with a cannula, can be inserted into the container very easily, as the sampling unit acts as a guide. The sampling unit preferably extends to just before the bottom of the container, ensuring that the body fluid can be extracted even when the fluid level is very low.In any case, it must be ensured that the sample is taken in such a way that the body fluid to be stored in the container does not unintentionally leak from the container during or after the procedure. The self-sealing membrane has proven particularly advantageous in this regard, as no manual intervention by the user of the set is required. The membrane seals the interior airtight against the environment both when and after it is punctured, preventing air from entering the container from the surroundings during the sample collection process, or vice versa. At the same time, the self-sealing membrane allows for the storage of a fluid quantity exceeding the fluid level at the other end of the container.In other words, the container can be filled with any amount of body fluid without the body fluid being able to leak out of the container via the sampling unit.

[0017] An advantageous embodiment of the invention provides that the membrane has a predetermined puncture point, the membrane preferably being slit in the area of ​​the puncture point. By forming a predetermined puncture point, it is ensured that a user of the set does not have to pierce or puncture the membrane of the dispensing unit arbitrarily. Rather, the predetermined puncture point advantageously specifies where the dispensing device is to be inserted. If the membrane is slit in the area of ​​the puncture point, the insertion of the dispensing device is further simplified, since it then only needs to be inserted through the slit puncture point. It is preferably provided that the slit puncture point nevertheless ensures an airtight and liquid-tight seal between the interior of the container and the environment during and after dispensing with the dispensing device.

[0018] A particularly advantageous further development of the method according to the invention provides that the container is cup-shaped. Containers for storing bodily fluids are typically cup-shaped due to ease of handling. It is preferably possible for the horizontal cross-section of the container to increase in the longitudinal direction. Alternatively, the cross-section can remain constant in the longitudinal direction.

[0019] Preferably, the lid can have a circular cross-section. Similarly, the container can be cup-shaped and also have a circular cross-section, so that the lid and the container are compatible.

[0020] A further embodiment of the invention provides that the lid is secured to the container by means of a fastening device, preferably a screw thread. A screw thread allows the lid to be attached to the container particularly easily, securely, and quickly. The screw thread ensures that the bodily fluid contained in the container cannot leak out. Nevertheless, the dispensing unit allows for removal of the fluid from the container without having to unscrew the lid.

[0021] Furthermore, it is particularly advantageous if the lid's diameter is larger than the container's diameter, so that the lid at least partially surrounds the container when the set is in its sealing position. This design is especially beneficial if the lid has a base and a rim, as the base seals the container, particularly in the sealing position, and the rim surrounds it. Preferably, the lid's fastening element is located on an inner surface of the rim. Simultaneously, the container can also have a fastening element in a corresponding area. For example, the lid could have a screw thread that can be screwed to the container via a corresponding thread located on the container's upper edge.

[0022] An advantageous embodiment of the invention provides that an opening cross-section of the dispensing unit lies in the same plane as a lid surface, in particular an underside of the lid. In other words, the lid surface is flat. In this way, the set is particularly compact and can be easily stacked.

[0023] A further embodiment of the invention provides that the lid has at least one airflow channel through which air can flow from the surroundings into the interior of the container, either before or after passing through the gap, when the set is in the vented position. In normal use of the set, the lid may be screwed onto the container in the sealing position, with the lid not resting directly on an end face of the container. Preferably, the lid is only in contact with the container via its rim. An end face of the container is not in contact with the underside of the lid.However, if the lid is screwed so tightly to the container that contact is established between the end face of the container and the base of the lid, there is a risk that the container cannot be ventilated, as there is a positive fit between the lid base and the container wall. In such a case, the airflow channel is particularly advantageous, as it allows air to flow into the interior of the container even if the set has been incorrectly assembled in the manner described above. The airflow channel is preferably associated with a ventilation element, so that when the set is in the ventilated position, air can first flow through the airflow channel and then through the gap formed by the ventilation element into the interior of the container.

[0024] According to an advantageous embodiment of the set according to the invention, the airflow channel is further provided that it is arranged in a contact area of ​​the lid and the container in the sealing position of the set, in particular in a circumferential, annular end face of the container. This arrangement enables ventilation of the interior of the container if the lid is positioned on the container in such a way that an inflow due to contact between the lid and the container in the contact area is prevented.

[0025] The aforementioned problem is also solved according to the method with the features of claim 13. An advantageous embodiment is described in the associated dependent claim.

[0026] This method is suitable for creating pressure equalization between the interior of a container within a set. The method comprises the following steps: First, body fluid and air are present in the interior of the container. The set is in a sealed position, preventing the escape of body fluid and air due to a tight seal between the lid and the container.

[0027] In a second step, the body fluid is extracted from the container. The kit's extraction unit is used for this purpose. For example, the body fluid can be drawn from the container using a syringe. This extraction reduces the pressure inside the container because the tight seal between the lid and the container prevents air from entering to compensate for the fluid loss. As a result, the container is under negative pressure relative to its surroundings. This negative pressure can deform the lid and / or the container.

[0028] In a third process step, the set is deformed and then moved from the sealing position to the ventilation position, allowing ambient air to flow into the interior of the container and ventilate it. As a result of this ventilation, the set returns to the sealing position.

[0029] The advantages mentioned in relation to the set according to the invention are achieved analogously by the method described above.

[0030] A preferred embodiment of the invention provides that the set automatically switches between the sealed and vented positions. In other words, the set switches between positions without manual intervention. A user of the set can therefore easily remove bodily fluids from the container without having to perform any additional steps to vent the set, as the set is self-venting. In particular, it is not necessary to remove the set's lid from the container during removal to vent the interior. Instead, the removal of bodily fluids from the container's interior occurs without interruption, as the set self-vents as soon as the pressure inside the container falls below a certain threshold. This threshold can preferably be predetermined by the choice of material for the lid and / or the container. Examples of implementation

[0031] The set and the method according to the invention are explained in more detail below with reference to an exemplary embodiment shown in the figures. These show: Fig. 1: A three-dimensional view of a set according to the invention. Fig. 2: An underside of a lid of the set made of Figure 1 Fig. 3a A detailed view of the underside of the lid made of Figure 2 , with the set in a sealing position. Fig. 3b A detailed view of the underside of the lid made of Figure 2 , with the set in a ventilation position. Fig. 4 A vertical section through the set made of Figure 1 Fig. 5 Another vertical section through the set of Figure 1 Fig. 6a A detailed view of the section from Figure 5 Fig. 6b Another detailed view of the section from Figure 5 , with an air duct of the set open. Fig. 7 A vertical section through a dispensing unit of the set made of Figure 1 .

[0032] One embodiment, which is described in the Figures 1 to 4 As shown, a set according to the invention comprises 1. The set 1 used to store body fluids 2, For example, urine. The set 1 includes a container 3 for the storage of at least one body fluid 2 and a lid 4. The container 3 It is cup-shaped and has a circular shape that points towards a top. 32 of the container 3 magnifying cross-section. The lid 4 is intended to be the container 3 to seal airtight. For this purpose, the lid 4 also circular in its cross-section, with a diameter 18 of the lid 4 is larger than a diameter 19 of the container 3, so that the lid 4 on the container 3can be placed on it. Furthermore, the lid includes 4 a lid edge 25, which is perpendicular to a lid base 26 of the lid 4 extends. In this way, the lid encompasses 4 the container 3 at least partially, if it is on the container 3 lies down.

[0033] To ensure an airtight seal between the lid 4 and container 3 to be able to train, the lid indicates 4 and the container 3 one fastening element each 16 which is in the form of a screw thread 17 is trained. In this way, the lid can be opened. 4 simply and quickly onto the container 3 unscrew it. The screw thread is involved. 17 of the container 3 on an upper circumferential edge 27 on the outside of the container 3 is arranged. The screw thread 17of the lid 4 is on an inside edge of the lid 25 arranged. In the closed position, the lid rim grips 25 the container 3. The container 3 and the lid 4 They can then be secured by screwing the lid shut. 4 on the container 3 in an airtight sealing position of the set 1 transfer, in which there is an outflow and inflow of air and an outflow of body fluid 2 from the interior 5 of the container 3 is prevented.

[0034] The set 1 It can be switched between a sealed position and a vented position. Furthermore, the set can 1 also be in a starting position in which the lid 4 from the container 3 is separated. In the sealing position, the lid is 4 on the container 3unscrewed and an escape of air or body fluid 2 is prevented. The sealing position is in the Figure 1 shown.

[0035] The set also includes 1 a sampling unit 6. The extraction unit 6 enables the removal of body fluid 2 with the lid screwed on 4. This is tubular in shape, with a first end 12 the extraction unit 6 is openly formed, while the opposite second end 13 the extraction unit 6 with a membrane 14 It is equipped with a membrane that closes automatically during and after piercing. 14 The sealing surface, like the sealing surface, prevents air from escaping or entering the interior. The membrane is also... 14 for body fluid 2 Impermeable. An opening cross-section 20 the extraction unit6 lies in a plane with a lid surface 21, namely the underside 11 of the lid 4. The lid 4 Therefore, despite the presence of the extraction unit, 6 just formed. An opening cross-section 20 the extraction unit 6 is decentralized from a central point 28 of the lid 4 or the container 3 arranged so that a small amount of body fluid 2 with the container tilted 3 also by means of the extraction unit 6 from the container 3 can be removed.

[0036] To obtain a specific amount for analysis of body fluid 2 from the container 3 to remove, the extraction unit 6 a sampling device, such as a syringe with or without a needle, can be used for this purpose through the membrane. 14 through into the body fluid2 be introduced. Upon reaching the end of the extraction unit 6 arranged membrane 14 The syringe is inserted through a predetermined injection site. 15 through, as can be seen in particular from the Figure 7 This is evident. By means of a vacuum manually applied to the sampling device, in particular by drawing up the syringe, the body fluid can be extracted. 2 from the container 3 via the extraction unit 6 The sampling medium can therefore be sucked out even with the lid screwed on. 4 especially easy thanks to the extraction unit 6 through into the interior 5 be introduced, whereby the self-sealing membrane 14 ensures that the body fluid 2 even when the membrane is punctured 14 airtight from the environment 7 is separated. Likewise, the membrane closes. 14After piercing, the seal automatically returns to its original position. The sealing position is therefore maintained even if the syringe is inside the casing. 5 is located.

[0037] The body fluid can be extracted using the syringe. 2 from the interior 5 the container is suctioned out, thus removing a certain amount of body fluid 2 to be extracted. During the aspiration of body fluids 2 The amount in the interior decreases 5 of the container 3 prevailing pressure due to the airtight seal of the container 3 by means of the lid 4. Inside 5 of the container 3 A negative pressure is created relative to the surroundings. 7 of the set 1 The reduction in pressure makes it increasingly difficult to extract body fluids. 2 from the container 3,because of an influx of air in response to the removed body fluid 2 due to the sealing position of the set 1 This is prevented when a certain negative pressure prevails within the interior. 5 is a further removal of body fluid 2 Suction is no longer possible.

[0038] To prevent this, when a predetermined pressure difference is reached between the interior and exterior, pressure is released. 5 prevailing pressure and that of the environment 7, which corresponds to atmospheric pressure, the lid 4 The first set is deformed. In particular, the base of the lid is warped. 26 in the direction of a floor 31 of the container 3, how particularly good in Figure 5 This is evident. The pressure difference at which such a deformation of the lid occurs. 4This takes place by means of a choice of material used for the formation of the lid. 4 and / or the container 3 customizable.

[0039] The lid 4 of the set 1 features two ventilation elements 8 on, which is on an underside 11 of the lid 4 are arranged in a peripheral area of ​​the same. The ventilation elements 8 are each in the form of a cam 10 trained, as particularly well from the Figures 2 and 3 as is evident.

[0040] As a result of the deformation of the lid 4 Are the cams coming? 10 each with a wall 29 of the container in contact. In this way, a gap is created. 9 between the lid 4 and the container 3 trained, as in Figure 3b ) is evident. The set 1In this process, it is switched from a sealed position to a ventilated position, in which air from the surroundings is allowed to flow in. 7 into the interior 5 of the container 3 This is made possible. As a result, the interior 5 of the container 3 ventilated and the negative pressure lifted, allowing for the removal of body fluid 2 by extracting them from the interior 5 This is made possible again. During the continuous pressure equalization resulting from the inflow of air from the surroundings. 7 The lid is deformed 4 back to a starting position and the gap 9 The size is reduced. This occurs when pressure equalization with the surroundings is complete. 7 Is gap 9 completely closed and the set 1 is back in the sealing position, as is particularly evident in Figure 3a ) The deformation of the lid is evident.4 and the associated formation of the gap 9 This happens automatically, i.e., without manual intervention. A user of the set 1 can the body fluid 2 thus particularly easy from inside 5 of the container 3 vacuuming without removing the lid. 4 from the container 3 for pressure equalization between the interior 5 of the container 3 and the surrounding area 7 to have to worry. Rather, the body fluid is suctioned out. 2 from the interior 5 of the container 3, without the user of the set 1 noticed a change.

[0041] This process, i.e., the transition between the sealing position and the ventilation position of the set, 1, repeats itself depending on the amount of body fluid to be extracted 2. The amount of body fluid 2,which is removed before the set 1 The process by which the device automatically switches to the ventilation position is essentially always the same. However, the user does not notice the transition between the sealed and ventilation positions, as no intervention is required.

[0042] The plan is for the lid to 4 is screwed on in such a way that between an end face 30 of the container 3 and the front surface 24 of the lid 4 a circumferential gap 9 remains, so that the front surfaces 24, 30 They should not come into contact with each other. Contact should only occur in the area of ​​the two screw threads. 17 are available.

[0043] However, it turned out that the lid 4 can be screwed on incorrectly in such a way that the two end faces 24, 30come into at least partial contact with each other. Such a screw connection is particularly common in the Figures 6a ) and 6b ) evident. In such a case, the interior 5 of the container 3 even when the set is available 1 In the ventilation position, ventilation is not possible, or at least not sufficiently fast, because air cannot flow in due to the contact of the two end faces. 24, 30 is inhibited or prevented. In this case, an airflow duct enables 22, the one on the front surface 24 of the lid 4 is arranged so that air flows through the gap before passing through it. 9 from the surrounding area 7 into the interior 5 of the container 3 This allows the airflow to flow. For this purpose, the airflow channel is used. 22 in a contact area 23 of the lid 4 and the container 3 in the sealing position of the set 1arranged. The airflow duct 22 is the respective cam 10 assigned. In case of incorrect screwing on of the lid. 4 on the container 3 can the set 1 so that they can still be moved into the ventilation position. Reference symbol list

[0044] 1 Set 2 Body fluid 3 Container 4 Lid 5 Interior 6 Sampling unit 7 Environment 8 Ventilation element 9 Gap 10 Cam 11 Underside of lid 12 First end 13 Second end 14 Membrane 15 Puncture point 16 Fastener 17 Screw thread 18 Lid diameter 19 Container diameter 20 Sampling unit opening cross-section 21 Lid surface 22 Airflow channel 23 Contact area 24 Lid end face 25 Lid rim 26 Lid base 27 Container rim 28 Center point 29 Wall 30 Wall end face 31 Container bottom 32 Container top

Claims

1. A set (1), comprising - at least one container (3) for storing at least one bodily fluid (2), and - at least one lid (4) for closing the container (3), - wherein the container (3) has at least one interior (5) for storing the bodily fluid (2), - wherein the set (1) can be transferred at least between a sealing position and a ventilating position, - wherein the lid (4) and the container (3) together form an airtight sealing seat in the sealing position of the set (1), - wherein the lid (4) has a removal unit (6), by means of which the bodily fluid (2) can be removed from the container (3) even with the set (1) in the sealing position, - given a vacuum inside of the interior (5) of the container (3) as a result of removing the bodily fluid (2) from the container (3) via the removal unit (6), the pressure differential between the interior (5) of the container (3) and the environment (7) makes it possible to deform the lid (4) and / or the container (3), such that the set (1) can be transferred from the sealing position into the ventilating position, wherein, with the set (1) in the ventilating position, air flows into the interior (5) of the container (3) from the environment (7) and ventilates the interior (5) of the container (3), characterized in that a lid (4) has at least one ventilating element (8), which, when the set (1) is in the ventilating position, generates at least one gap (9) in the sealing seat between the lid (4) and the container (3) as a result of the deformation of the lid (4) and / or the container (3) due to contact with the container (3) and / or the lid (4), through which air can flow from the environment (7) into the interior (5) of the container (3).

2. The set (1) according to claim 1, characterized in that the ventilating element (8) is designed as a cam (10).

3. The set (1) according to claim 2, characterized in that the cam (10) is arranged on a lower side (11) of the lid (4) that faces the container (3) with the set (1) in the sealing position.

4. The set (1) according to one of the preceding claims, characterized in that the removal unit (6) is tubular in design, wherein the removal unit (6) is open at a first end (12), and provided with a membrane (14) at a second end (13) that self-seals while and after being pierced.

5. The set (1) according to claim 4, characterized in that the membranae (14) has a predetermined puncture site (15), wherein the membrane (14) is preferably slit in the area of the puncture site (15).

6. The set (1) according to one of the preceding claims, characterized in that the container (3) is cup-shaped.

7. The set (1) according to one of the preceding claims, characterized in that the lid (4) has a circular cross section.

8. The set (1) according to one of the preceding claims, characterized in that the lid (4) can be held on the container (3) by means of a fastener (16), wherein the fastener (16) is preferably a screw thread (17).

9. The set (1) according to one of the preceding claims, characterized in that a diameter (18) of the lid (4) is larger than a diameter (19) of the container (3) (19),so that the lid (4) at least partially envelops the container (3) in the sealing position of the set (1).

10. The set (1) according to one of the preceding claims, characterized in that an opening cross section (20) of the removal unit (20) (6) lies in a plane with a lid surface (21), in particular a lower side (11) of the lid (4).

11. The set (1) according to one of the preceding claims, characterized in that the lid (4) has at least one air flow channel (22), though which air can flow from the environment (7) into the interior (5) of the container (3) before or after flowing through the gap (9) with the set (1) in the ventilating position.

12. The set (1) according to claim 11, characterized in that the air flow channel (22) is arranged in a contact area (23) of the lid (4) and the container (3) in the sealing position of the set (1), in particular in a circumferential, ring-shaped end face (30) of the container (3).

13. A method for establishing a pressure equalization between an interior (5) of a container (3) of a set (1) according to one of claims 1 to 12 and an environment (7), comprising the following procedural steps: - The set (1) is in the sealing position, and a bodily fluid (2) and air are in the interior (5) of the container (3). - A pressure in the interior (5) of the container (3) is decreased by removing a bodily fluid (2) from the interior (5) through the removal unit (6), so that a vacuum in the interior (5) of the container (3) is created in relation to an environment (7) of the set (1), and the lid (4) and / or the container (3) of the set (1) is deformed. - Due to the deformation, the set (1) is transferred from the sealing position into the ventilating position, in which air flows from the environment (7) into the interior (5) of the container (3), and ventilates the interior (5) of the container (3), as a result of which the set (1) is transferred back into the sealing position.

14. The method according to claim 13, characterized in that the set (1) is automatically transferred between the sealing position and the ventilating position.