Deodorant compositions

Abstract

The present invention relates to a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 measured according to Test Method A. Process for the preparation of the deodorant compositions and product. Non-therapeutic use of the deodorant composition.

Description

[0001] Deodorant Compositions

[0002] Field of the Invention

[0003] Deodorant compositions. Process for the preparation of the deodorant compositions and product. Non-therapeutic use of a deodorant composition.

[0004] Background of the Invention

[0005] Deodorant and antiperspirant products are designed to control sweating and / or to control the odour associated with sweating. The formulation is usually dispensed from a package suitable for application to the consumer's body, usually to the underarm area.

[0006] WO 2017 / 182358 A1 describes a deodorant composition in the form of a solid stick comprising a glycol composition, a structurant and water. The composition described in WO 2017 / 182358 A1 is indicated to improve the characteristics of the sticks, in terms of stick sweating, and to reduce or eliminate any insoluble matter such as white specks in the stick.

[0007] Deodorant compositions comprising a glycol composition, a structurant and water may cause skin irritation for some users. Such compositions have a high pH, for example a pH from 8 to11 , and it is hypothesized that a high pH contributes to the skin irritation that may occur for some users.

[0008] Vitamin B3, specifically the niacinamide component of Vitamin B3, has been suggested to play a part in the maintenance of the epidermal permeability barrier when applied to dry skin. Tanno et al.-, British Journal of Dermatology (2000); 143; 524-531. of the Invention

[0009] The present invention relates to a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 according to Test Method A. Although deodorant compositions having a pH of from 8 to 11 may irritate the skin of some users, it is desirable to retain the pH of from 8 to 11 as it provides antimicrobial activity, thereby reducing microbial transformations of odour precursors into malodorous materials.

[0010] Deodorant compositions having a pH of from 8 to 11 and comprising a vitamin B3 component not only enable deodorant compositions to provide the desired antimicrobial activity without the need for the addition of antimicrobial agents, but they are also observed not to cause skin irritation to some users, as may be observed by users of deodorant compositions having a pH of 8 to 11 that do not comprise a vitamin B3 component.

[0011] The antimicrobial activity of deodorant compositions having a pH of from 8 to 11 addresses the desire to formulate products with a reduced number of components. Not only can deodorant compositions be formulated to be free from astringent metal salts (such as aluminum and zirconium) and triglycerides, but it is also now possible for deodorant compositions to be free from additional antimicrobial agents.

[0012] An additional object of the invention is the provision of a deodorant stick composition comprising a vitamin B3 component, wherein the vitamin B3 component is stable. In particular, wherein the vitamin B3 component is stable and has a suitable shelf-life corresponding to the typical shelf life of personal care products, for example up to 3 years. In particular, wherein the vitamin B3 component is stable, and the deodorant composition comprises less than 220 ppm nicotinic acid.

[0013] A second aspect of the invention is a process for the preparation of the deodorant compositions and product.

[0014] A third aspect of the invention is a non-therapeutic use of the deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 according to Test Method A, for one or more outcomes selected from the group consisting of the increased hydration of the skin of the user, decreased TEWL of the skin of the user, improved visual erythema of the skin of the user, decreased visual dryness of the skin of the user and combinations thereof.

[0015] According to a fourth aspect of the invention, there is provided the non-therapeutic use of a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 according to Test Method A for preventing or reducing malodour and also mitigating irritation of the skin. This may be particularly relevant to a user that is irritated by a deodorant composition having a pH of from 8 to 11 , i.e. a user that has sensitivity to high pH compositions.

[0016] Detailed Description of the Invention

[0017] The present invention relates to a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component, and water, wherein the composition has a pH of from 8 to 11 according to Test Method A.

[0018] Preferably the vitamin B3 component is selected from the group consisting of niacinamide, nicotinic acid, niacinamide riboside, niacinamide analogue, niacinamide derivative, nicotinic acid analogue, nicotinic acid derivative, niacinamide riboside analogue, niacinamide riboside derivative and mixtures thereof. Exemplary derivatives are described in US 2020 / 316050 A1 and US 6,224,888 B1. More preferably the vitamin B3 component comprises niacinamide. More preferably the vitamin B3 component consists of niacinamide.

[0019] The deodorant composition preferably comprises from 0.5 wt% to 6 wt% niacinamide, from 1 wt% to 5 wt% niacinamide. Preferably the deodorant composition comprises from 2 wt% to 4 wt% niacinamide.

[0020] The deodorant composition preferably comprises from 0 ppm to 220 ppm nicotinic acid, more preferably from 0 ppm to 50 ppm nicotinic acid, most preferably from 0 ppm to 25 ppm nicotinic acid.

[0021] The deodorant composition preferably comprises from 26 wt % to 65 wt % glycol composition, more preferably from 34 wt % to 58 wt % glycol composition, and most preferably from 41 wt % to 50.25 wt % glycol composition.

[0022] Herein, the glycol composition comprises propylene glycol and / or di-propylene glycol. More preferably, the glycol composition consists of propylene glycol and di-propylene glycol. The deodorant composition preferably comprises from 24 wt % to 55 wt % di-propylene glycol more preferably from 30 wt % to 50 wt% di-propylene glycol and most preferably from 36 wt % to 44 wt % di-propylene glycol.

[0023] The deodorant composition preferably comprises from 2 wt % to 10 wt % propylene glycol, more preferably from 4 wt % to 8 wt % propylene glycol, and most preferably from 5 wt % to 6.25 wt % propylene glycol.

[0024] The deodorant composition preferably comprises a glycol composition preferably comprising a weight ratio of di-propylene glycol to propylene glycol of from 2.4:1 to 27.5:1; more preferably from 3.75:1 to 12.5:1 ; most preferably from 5.76:1 to 8.8:1.

[0025] The deodorant composition comprises a glycol composition preferably comprising from 50 wt% to 95 wt% di-propylene glycol; more preferably from 70 wt% to 92 wt% di-propylene glycol; most preferably from 80 wt% to 90 wt% di-propylene glycol.

[0026] The deodorant composition comprises a glycol composition preferably comprising from 5 wt% to 50 wt% propylene glycol; more preferably from 8 wt% to 30 wt% propylene glycol; most preferably from 10 wt% to 20 wt% propylene glycol.

[0027] The deodorant composition comprises a glycol composition preferably comprising from 50 wt% to 95 wt% di-propylene glycol and from 5 wt% to 50 wt% propylene glycol; more preferably from 70 wt% to 92 wt% di-propylene glycol and from 8 wt% to 30 wt% propylene glycol; most preferably from 80 wt% to 90 wt% di-propylene glycol and from 10 wt% to 20 wt% propylene glycol.

[0028] The deodorant composition preferably comprises from 10 to 25 wt% glycerol, more preferably from 12 to 22 wt% glycerol, and most preferably from 15 to 20 wt% glycerol.

[0029] The deodorant composition comprises a C12 to C22 fatty acid salt component. C12 to C22 fatty acid salt component is typically a salt of a linear or branched alkyl chain saturated fatty acid. The salt is typically an alkali salt, such as a potassium or sodium salt, preferably the salt is sodium salt.

[0030] In a preferred embodiment the deodorant composition comprises a saturated linear alkyl chain C18 to C22 fatty acid salt component, preferably sodium stearate or sodium behenate. The deodorant composition comprises water. Preferably the deodorant composition comprises from 17 wt % to 35 wt% water, preferably from 20 wt % to 30 wt% water, more preferably from 22 wt % to 28 wt% water.

[0031] Preferably, the deodorant composition has a weight ratio of the glycol composition to water is from 1 :1 to 3.8:1 , from 1.13:1 to 2.9:1 , from 1.46:1 to 2.28:1.

[0032] The deodorant composition has a pH that is from 8 to 11 , preferably from 8.5 to 11 , and more preferably from 9 to 10.5. The pH of the composition is measured by Test Method A. These pH levels help balance the antimicrobial and low irritancy properties of the composition.

[0033] A preferred additional component of compositions of the invention is an additional vitamin including those selected from alternative vitamin B options: B1 (thiamin); B2 (riboflavin); B5 (pantothenic acid); B6 (pyridoxine); B7 (biotin); B9 (folate [folic acid]); B12 (cobalamin) and, also vitamins C, D and E. The additional enzyme may enhance the skin care benefits of the invention, in particular the anti-irritation benefits.

[0034] A particularly preferred additional vitamin is vitamin E, and especially vitamin E acetate.

[0035] The deodorant composition may comprise a fatty alcohol, wherein the fatty alcohol comprises stearyl alcohol, cetearyl alcohol and behenyl alcohol. Preferably the deodorant composition comprises one or more fatty alcohols selected from the group consisting of stearyl alcohol, cetearyl alcohol, behenyl alcohol and mixtures thereof. Preferably, the deodorant composition comprises stearyl alcohol.

[0036] The deodorant composition comprises pH regulators such as C12 to C22 fatty acids, for example, stearic acid. Preferably, the deodorant composition comprises stearic acid.

[0037] The composition may comprise one or more of any of the following additional optional ingredients such as: dyes, pigments or colourants; antioxidants such as butylated hydroxytoluene (BHT); surfactants, including nonionic surfactants, such as polymer based nonionic surfactants, for example poloxamine (Tetronic® 1307); chelating agents such as disodium EDTA; deodorizing agents; silicones; and, antifoam agents, for example silicone / hydrated silica antifoam agents.

[0038] In an aspect of the invention the invention is directed towards a process for the preparation of a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component, and water, wherein the composition has a pH of from 8 to 11 according to Test Method A. An exemplary process for preparing the deodorant composition is described in WO 2017 / 182358 A1. The process comprises the steps of: a. Mix and heat optional chelating agent, vitamin B3 component and water; b. Add glycol composition and glycerol, c. Heat blend of step b. to 85 °C d. Add and mix C12 to C22 fatty acid salt component; e. Optionally add additional optional components; f. Mix and cool to 74 °C; g. Mix and cool to 72 °C;

[0039] The product of step g. may be added to a receptable. The receptacle may be the final product receptacle, for example, the packaging. Preferably the receptacle is the final product receptacle. Final product means product suitable for use. Preferably the final product is in the form of a stick product. Exemplary stick dispenser product packaging is illustrated by current products such as the DOVE deodorant stick product (Unilever) illustrated by www.dove.com.

[0040] Herein, stick compositions and products may be considered to be solid compositions under ambient conditions, which should be understood as being 25°C and 1 atmosphere pressure.

[0041] Stick products may be packaged so that there is a plastic dome on top of the stick, between the solid stick formulation and the cap. The dome is removed and discarded by the consumer prior to first use. There is also provided a cap which can be replaced after each use.

[0042] In aspect of the invention the invention is directed towards a stick product comprising a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component, and water, wherein the composition has a pH of from 8 to 11 according to Test Method A.

[0043] An aspect of the invention is a non-therapeutic use of the deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 according to Test Method A, for one or more outcomes selected from the group consisting of the increased hydration of the skin of the user, decreased TEWL of the skin of the user, improved visual erythema of the skin of the user, decreased visual dryness of the skin of the user and combinations thereof.

[0044] A further aspect of the invention is the non-therapeutic use of a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 measured according to Test Method A for preventing or reducing malodour and also mitigating irritation of the skin.

[0045] The methods and uses of the present invention are typically achieved by the topical application of a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 measured according to Test Method A.

[0046] The topical application typically employed in the use of the present invention is to the human skin, for example the underarm regions and / or forearm regions. In particular the underarm regions of the human body.

[0047] Examples

[0048] Method of Preparing Example 1:

[0049] Once EDTA has dissolved, add glycerol, and glycol composition to beaker. Mix beaker contents while heating to 85 °C.

[0050] At 85 °C add the sodium stearate and any additional optional ingredient and fatty alcohol, mix until dissolved.

[0051] Mix for 5 mins then add the Poloxamine copolymer surfactant and simethicone.

[0052] Continue mixing for 5 minutes then start cooling to 74 °C.

[0053] At 74 °C add pH regulator and additional optional ingredients if required and mix for 5 minutes.

[0054] Continue stirring / cooling to 72 °C.

[0055] Pour into barrels at 72 °C to finalize the stick product. Table 1 : Deodorant compositions

[0056] Example 1 had a pH of 10.3 on average measured according to Test Method A.

[0057] In a further example, the deodorant composition comprises from 0.01 wt% to 0.15 wt% vitamin E acetate.

[0058] Example 1 demonstrated a non-therapeutic use of a deodorant composition comprising a vitamin B3 component, a glycol composition, glycerol, a C12 to C22 fatty acid salt component and water, wherein the composition has a pH of from 8 to 11 according to Test Method A for preventing or reducing irritation of the skin of the user that has been contacted with the deodorant composition and that is usually irritated by a deodorant composition having a pH of from 8 to 11 that does not comprise a vitamin B3 component (Example A).

[0059] Stability Testing:

[0060] Multiple samples of Example 1 were stored at standard pressure, about 40 % humidity, and at temperatures between 5 °C to 45 °C for 12 weeks. Maximum nicotinic acid content was measured to be from 5 ppm to 22 ppm.

[0061] Example 1 demonstrates a deodorant composition comprising a vitamin B3 component, in particular niacinamide, wherein the niacinamide is stable at pH from 8 to 11 at between 5 °C to 45 °C for 12 weeks. Example 1 demonstrates a deodorant composition comprising a vitamin B3 component, a glycol composition comprising propylene glycol and / or di-propylene glycol, glycerol, a C12 to C22 fatty acid salt component, and water, wherein the composition has a pH of from 8 to 11 measured according to Test Method A , wherein the vitamin B3 component comprises niacinamide and the niacinamide is stable at pH from 8 to 11 at between 5 °C to 45 °C for 12 weeks.

[0062] Example 1 demonstrates a deodorant composition comprising a vitamin B3 component, a glycol composition comprising propylene glycol and / or di-propylene glycol, glycerol, a C12 to C22 fatty acid salt component, and water, wherein the composition has a pH of from 8 to 11 measured according to Test Method A , wherein the vitamin B3 component comprises niacinamide and the niacinamide is stable at pH of on average of 10.3 at between 5 °C to 45 °C for 12 weeks.

[0063] Test Method A: pH measurement of deodorant

[0064] The pH of compositions according to the invention is measured according to the following method. This method was also used to measure the pH of Example 1.

[0065] The composition is first homogenized or dissolved in water by heating at between 60 °C to 65 °C at a concentration of 10% by weight and then cooled to 25 °CThe pH of the resulting dispersion or solution is then measured at 25 °C using a conventional pH meter according to the art, for example: SevenCompactTM pH / lon Meter S220 and pH electrode (e.g. Mettler Toledo Inlab® Expert Pro pH electrode). Calibrated using standard Buffer solutions e.g. pH 4, 7, 10. The pH is typically an average value based on several replicates.

Claims

Claims1. A deodorant composition comprising a vitamin B3 component, a glycol composition comprising propylene glycol and / or di-propylene glycol, glycerol, a C12 to C22 fatty acid salt component, and water, wherein the composition has a pH of from 8 to 11 measured according to Test Method A.

2. A deodorant composition according to claim 1, wherein the vitamin B3 component is selected from the group consisting of niacinamide, nicotinic acid, niacinamide riboside, niacinamide analogue, niacinamide derivative, nicotinic acid analogue, nicotinic acid derivative, niacinamide riboside analogue, niacinamide riboside derivative and mixtures thereof.

3. A deodorant composition according to claim 1 or 2, comprising 1 wt% to 5 wt% niacinamide.

4. A deodorant composition according to any one of claims 1 to 3, wherein the glycol composition comprises propylene glycol and di-propylene glycol.

5. A deodorant composition according to any one of claims 1 to 4 in the form of a stick.

6. A deodorant composition according to any one of claims 1 to 5, wherein the ratio of dipropylene glycol: propylene glycol is from 2.4:1 to 27.5:1.

7. A deodorant composition according to any one of claims 1 to 6, wherein the ratio of water to the glycol composition is from 1 :1 to 3.8:1.

8. A deodorant composition according to any one of claims 1 to 7, wherein the glycol composition comprises from 5 wt% to 50 wt% propylene glycol.

9. A deodorant composition according to any one of claims 1 to 8, wherein the glycol composition comprises from 50 wt% to 95 wt% di-propylene glycol.

10. A deodorant composition according to any one of claims 1 to 9, comprising from 12 wt% to 25 wt% glycerol.

11. A deodorant composition according to any one of claims 1 to 10, comprising from 2 wt% to 10 wt% C12 to C22 fatty acid salt component wherein the C12 to C22 fatty acid salt component is sodium stearate.

12. A deodorant composition according to any one of claims 1 to 11 , wherein the deodorant composition comprises stearyl alcohol and stearic acid.

13. A process for the preparation of a composition according to any one of claims 1 to 12.

14. A stick product comprising the composition according to any one of claims 1 to 12.

15. Use of a deodorant composition according to any one of claims 1 to 12 for preventing or reducing malodour and also mitigating irritation of the skin.

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