System with a measuring component for safe transdermal delivery

Abstract

SYSTEM WITH MEASURING COMPONENT FOR SAFE TRANSDERMAL DELIVERY: Skin treatment and transdermal delivery cartridge, including a microneedle array comprising one or more microneedles configured to prepare the skin for treatment, one or more sensors configured to measure one or more cartridge data points, and a chip configured to collect the data points and modulate the treatment accordingly. In addition, an applicator including a cartridge configured for removable coupling to the applicator, comprising a microneedle array comprising one or more microneedles configured to prepare the skin for treatment, one or more sensors configured to measure one or more cartridge data points, and a chip configured to collect the data points and modulate the treatment accordingly.Figure for the abridged version: none.

Description

Title of the invention: System with a measuring component for safe transdermal delivery SUMMARY

[0001] A cartridge for skin treatment and transdermal delivery is disclosed herein, including a microneedle(s) plane comprising one or more microneedles, configured to prepare the skin for providing treatment, one or more sensors configured to measure one or more cartridge data points, and a chip configured to collect the one or more cartridge data points and modulate the treatment according to the one or more data points.

[0002] In some embodiments, the chip is a near-field communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag. In some embodiments, the chip is an optical recognition sensor.

[0003] In some embodiments, the cartridge further includes a nozzle configured to cover one or more microneedles.

[0004] In some embodiments, one or more sensors are a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof. In some embodiments, one or more data points are a change in skin moisture, a cartridge pressure level, a change in skin temperature, a change in skin color, or a combination thereof.

[0005] In some embodiments, one or more microneedles are arranged in a matrix on the microneedle(s) plane.

[0006] In some embodiments, the processing is applied to a processing level selected from a plurality of processing levels. In some embodiments, the chip is configured to decrease the processing level when one or more data points reach or exceed one or more thresholds.

[0007] In certain embodiments, an applicator is disclosed herein including a cartridge configured to removably couple to the applicator, including a microneedle(s) plane comprising one or more microneedles, configured to prepare the skin for providing treatment, one or more sensors configured to measure one or more cartridge data points, and a chip configured to collect the one or more cartridge data points and modulate the treatment according to the one or more data points.

[0008] In some embodiments, the applicator includes a spring disposed inside an interface of the applicator, and a shutter configured to couple to the cartridge, where the spring and the shutter together comprise a twist-push mechanism configured to couple and remove the cartridge from the applicator.

[0009] In some embodiments, the applicator further includes a tip configured to cover one or more microneedles.

[0010] In some embodiments, the chip is a near-field communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag. In some embodiments, the chip is an optical recognition sensor.

[0011] In some embodiments, one or more sensors are a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof.

[0012] Also disclosed here is a method for safely applying a skin treatment by microneedle(s), including bringing the skin into contact with a microneedle(s) plane of an applicator, preparing the skin with one or more microneedles to a treatment level, measuring one or more cartridge data with one or more sensors on the cartridge, and adjusting the treatment level according to the one or more cartridge data.

[0013] In some embodiments, the method further includes comparing each data point of one or more data points to one or more thresholds, and when the threshold is reached or exceeded, reducing the treatment level. In some embodiments, the one or more cartridge data points include a cartridge pressure level, and the one or more thresholds include a pressure threshold. In some embodiments, the one or more cartridge data points include a skin temperature change, and the one or more thresholds include a temperature threshold. In some embodiments, the one or more cartridge data points include a skin color change, and the one or more thresholds include a color threshold.

[0014] This summary is proposed to present a selection of concepts in a simplified form, which are described in greater detail below in the detailed description. This summary is not intended to identify key features of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter. Description of drawings

[0015] The foregoing aspects and many related advantages of this invention will be more readily appreciated as they are better understood with reference to the detailed description that follows, when taken together with the accompanying drawings, on which:

[0016] [Fig 1] The [Fig 1] is a perspective view of an example applicator, in accordance with the present technology;

[0017] [Fig IB] The [Fig IB] is an exploded view of the applicator of Figure IA, according to the present technology;

[0018] [Fig 2A] [Fig 2B] Figures 2A-2B are close-up views of an example of an applicator, with a removable cartridge, in accordance with the present technology;

[0019] [Fig.3] Fig.3 is a close-up view of an example of an applicator with a tip, in accordance with the present technology;

[0020] [Fig 4A] The [Fig 4A] is an internal cross-sectional view of an example of an applicator, in accordance with the present technology;

[0021] [Fig 4B] The [Fig 4B] is the sample applicator chip of the [Fig 4A], according to the present technology;

[0022] [Fig.5] The [Fig.5] is an example of an applicator in use, in accordance with the present technology;

[0023] [Fig. 6] Fig. 6 is an example of a treatment adjustment method with a microneedle applicator, in accordance with the present technology; and

[0024] [Fig.7] The [Fig.7] is another example of a treatment adjustment method with a microneedle applicator, in accordance with the present technology. Detailed description

[0025] Microneedling is a cosmetic procedure that encourages collagen production using tiny, sterilized points or needles. It can help smooth, firm, and tone the skin and improve the appearance of scars, acne, pores, and wrinkles. Applicators, systems, and methods for applying a microneedling skin treatment (or therapy) are disclosed herein. In some embodiments, the applicator includes a cartridge with a microneedling array comprising one or more microneedles. In some embodiments, the cartridge further includes a chip used to collect one or more data points from a sensor system on the cartridge.The chip can use one or more data points to modulate the treatment delivered by the microneedles, including, but not limited to, reducing the treatment intensity, increasing the treatment intensity, starting treatment, or stopping treatment.

[0026] In some embodiments, the sensor system includes an optical sensor, a humidity sensor, a temperature sensor, a pressure sensor, or a combination thereof. In some embodiments, the chip and / or a device An external component, communicatively coupled to the chip, includes one or more thresholds, which can be used to determine when a processing level should be reduced, increased, stopped, or started. In some embodiments, the one or more thresholds include a color threshold (i.e., the user's skin color), a pressure threshold, a temperature threshold, a humidity threshold, a timer, or a combination thereof.

[0027] Figure IA is a perspective view of an example of an applicator 100 according to the present technology. In some embodiments, the applicator 100 includes a body 105, an actuator 115, an electrical port 107, and a button 110. In some embodiments, the applicator further includes an interface 120 configured to couple to a removable cartridge 125. In some embodiments, the cartridge 125 is removably coupled to the applicator 100. In this way, the cartridge 125 can be removed for cleaning or replaced to ensure that the cartridge 125 is hygienic.

[0028] In some embodiments, the body 120 is substantially cylindrical, but the body 120 can have any form factor. In some embodiments, the body 120 is longer than it is wide, to allow a user to hold the body 120 like a pen. In some embodiments, the body 120 is organically shaped, as shown in Figure IA. In some embodiments, the body 120 has a first end comprising an electrical port 107, and a second end configured to couple with the removable cartridge 120.

[0029] In some embodiments, the electrical port 107 is electrically coupled to a battery (as shown and described in [Fig. IB]) located inside the applicator 100. In some embodiments, the electrical port 107 is configured to facilitate an electrical connection between the battery and a charging device or a power outlet. In some embodiments, this can be facilitated by a cable or wire. In some embodiments, the electrical port 107 powers the applicator 100. In some embodiments, the electrical port 107 can charge the battery of the applicator 100, and the device can operate even when not connected to a power outlet or charging device.

[0030] In some embodiments, the applicator 100 includes a button 110. In some embodiments, the button 110 is configured to turn the applicator 100 on and / or off. In some embodiments, the button 110 can be used to facilitate wireless connection (Bluetooth™, Wi-Fi, or Zigbee) with another device, such as a smart device (as shown and described in [Fig. 7]). In some embodiments, the button 110 can start or stop the therapy, as described herein.

[0031] In some embodiments, the actuator 112 can start or stop the therapy (also referred to herein as "microneedle therapy" or "microneedle treatment"), as described herein. In some embodiments, the actuator 112 can increase or decrease the intensity of the therapy. In some embodiments, the actuator 112 may be a button, a touch-sensitive capacitive button, a switch, or similar.

[0032] During operation, the applicator 100 is charged or powered by the electrical port 107. In some embodiments, the button 110 can be pressed or operated to turn on the applicator 100. In some embodiments, a user can place a microneedle plate (such as the microneedle plate 130, as shown in [Fig. 1B]) on their skin. In some embodiments, the user can then press or otherwise operate the actuator 112 to initiate microneedling therapy while moving the applicator 100 over their skin. In some embodiments, the microneedle plate includes one or more microneedles (as shown in [Fig. 6]). As the user moves the applicator 100 over their skin, the one or more microneedles prepare the user's skin to deliver microneedling therapy.As used here, the term "prepare" means to penetrate the skin, exfoliate the skin, or otherwise disrupt the skin barrier.

[0033] Figure IB shows an exploded view of the applicator 100 of Figure IA, according to the present technology. As explained above, in some embodiments, the applicator 100 includes an electrical port 107, a button 110, a body 105, and an actuator 115. In some embodiments, the applicator 100 further includes a battery 121.

[0034] In some embodiments, the battery 121 is a rechargeable battery, a capacitor, or similar. In some embodiments, the battery 121 is charged with a wired connection via the electrical port 107. The battery 121 can power the applicator 100.

[0035] In some embodiments, the cartridge further includes an interface 120 configured to couple to a removable cartridge 125. In some embodiments, the interface 120 houses a spring 140, a shutter 123, and a pin 127. In some embodiments, the applicator 100 includes a removable cartridge 125. In some embodiments, the cartridge 125 houses a secondary spring 129. In some embodiments, the cartridge includes a microneedle plane 130. In some embodiments, the cartridge 125 contains the secondary spring and the pin 127. In some embodiments, the spring 140 and the secondary spring 129 work in tandem to remove the cartridge 125 from the applicator 100 and / or couple it to the applicator, as shown and described in more detail in Figures 2A-2B. In some embodiments, the 125 cartridge is coupled to A microneedle-layout 130 includes one or more microneedles (as shown in [Fig. 6]). In some embodiments, the obturator 123 is configured to couple with the cartridge 125. In some embodiments, the spring 140 and the obturator 123 together comprise a push-twist mechanism configured to couple the cartridge 125 to the applicator 100 and withdraw it from the applicator. During operation, when the cartridge 125 is pushed toward the obturator 123, the secondary spring 129 is compressed. At the same time, the spring 140 is compressed, allowing the cartridge 125 to couple and / or lock with the obturator 123 in order to retain the cartridge 125 in the interface 120.

[0036] Figures 2A and 2B are close-up views of an example of an applicator 100 with a removable cartridge 125 according to the present technology. In some embodiments, the applicator 100 includes an interface 120 configured to couple with the cartridge 125. In some embodiments, the cartridge 125 is configured to couple to the interface 120 with a "twist-locking mechanism", which may include a spring (such as spring 140) and a shutter (such as shutter 123). During operation, a user presses on cartridge 125 and twists it to release it from interface 120. To couple cartridge 125 to interface 120, the user can push cartridge 125 into interface 120 and twist it. In these embodiments, cartridge 125 locks with the shutter (such as shutter 123), thus retaining cartridge 125.

[0037] In some embodiments, the microneedle plane 130 includes one or more microneedles 175A, 175B, 175C... 175N. In some embodiments, the one or more microneedles 175A, 175B, 175C... 175N are arranged in a network. In some embodiments, the one or more microneedles 175A, 175B, 175C... 175N are configured to penetrate to a depth of 3 mm into the skin. In some embodiments, the one or more microneedles 175A, 175B, 175C... 175N are configured to penetrate to a depth of 10 µm into the skin. In some embodiments, one or more microneedles 175A, 175B, 175C... 175N are configured to exfoliate the skin as opposed to penetrating the skin.

[0038] Figure 3 is a close-up view of an example of an applicator 100, with a tip 135, according to the present technology. In some embodiments, the applicator 100 includes a tip 135. In some embodiments, the tip 135 is transparent or otherwise clear. In these embodiments, the tip 135 is configured to allow a user to see the microneedle plane(s) 130 through the tip 135. In other embodiments, the tip 135 is opaque. In some embodiments, the tip 135 is cylindrical, but the tip 135 It can take any shape or form factor. In some embodiments, the tip 135 is made of plastic, glass, metal, or a similar material. In some embodiments, the tip is configured to cover one or more microneedles (as shown in Figures 2A-2B) on the microneedle tray 130. This can prevent the one or more microneedles from bending, being damaged, and / or becoming contaminated. In some embodiments, the tip keeps the microneedles on the microneedle tray 130 clean and hygienic. In some embodiments, the tip 135 is also replaceable. During operation, a user can remove the tip 135 from the cartridge 123 before applying microneedling therapy to their skin.

[0039] Figure 4A is an internal cross-sectional view of an example of an applicator 100 according to the present technology. In some embodiments, the applicator 100 comprises a cartridge 125 with a microneedle plane 130. In some embodiments, the cartridge 125 contains a secondary spring 129 and a pin 127. In some embodiments, the cartridge 125 is removably coupled to an interface 120 of the applicator 100. In some embodiments, the interface 120 contains a spring 140 and a shutter 123.

[0040] In some embodiments, the applicator 100 further includes a chip 145. In some embodiments, the chip 145 is configured to collect one or more cartridge data points and modulate the processing based on these data points. In some embodiments, the applicator 100 further includes one or more sensors (as shown in [Fig. 5]). In some embodiments, each of the one or more sensors is configured to transmit cartridge data to the chip 145, as described herein. In some embodiments, the sensor system includes at least one humidity sensor, one pressure sensor, or one optical sensor. In some embodiments, the optical sensor is a camera.In some embodiments, the chip 145 is configured to receive one or more cartridge data points from one or more sensors and compare these data points to one or more thresholds. If the cartridge data points reach or exceed one or more thresholds, the chip instructs the applicator to reduce the treatment intensity. In some embodiments, the treatment (also referred to herein as microneedle therapy or microneedle treatment) can be delivered at a plurality of levels. In some embodiments, the cartridge data points determine at which of the plurality of levels the treatment is applied.

[0041] Figure 4B illustrates chip 145 of applicator example 100 of Figure 4A, according to the present technology. In some embodiments, chip 145 is a near-field communication (NFC) tag. In some modes In some embodiments, chip 145 is a microcontroller unit (MCU) tag. In some embodiments, chip 145 is an optical sensor system. In some embodiments, the optical sensor system is configured to encrypt one or more data points. In some embodiments, chip 145 can further communicate with an external device, such as a smart device. In some embodiments, chip 145 transmits one or more data points to the external device. In some embodiments, chip 145 can instruct the applicator to modulate the applied processing, including, but not limited to, increasing or decreasing the processing intensity, stopping the processing, or starting the processing.

[0042] Figure 5 is an example of an applicator 100 in use according to the present technology. In some embodiments, the cartridge 125 includes a sensor system. In some embodiments, the sensor system includes at least one pressure sensor 160, one humidity sensor 150, or one temperature sensor 155. In some embodiments, the sensor system includes a pressure sensor 160, a humidity sensor 150, a temperature sensor 155, or a combination thereof. In some embodiments, one or more of the sensors include a timer 180. In some embodiments, the timer 180 transmits time data to a chip (such as the chip 145). In some embodiments, the time data is the time elapsed since the applicator was switched on.In some embodiments, the time data refers to the time elapsed after the first application of microneedling therapy. In such embodiments, the timer can be triggered, for example, by pressure detection by the pressure sensor 160. In some embodiments, after a certain time has elapsed, the treatment level is reduced. In some embodiments, after a certain time has elapsed, the treatment is stopped.

[0043] During operation, the user can move the cartridge 125 over their skin S, as shown by the arrow. In some embodiments, the sensor system is configured to collect and monitor data, such as the pressure a user exerts on the cartridge, the user's skin temperature, and / or the user's skin moisture. In some embodiments, the moisture sensor 150 and the temperature sensor 155 (and / or the thermal couple 165) measure the skin moisture level and temperature for loop monitoring of the microneedling therapy performance. For example, if the moisture sensor detects a high moisture level on the user's skin and / or if the temperature sensor detects a high user skin temperature, the applicator 100 or an external device (such as the smart device 200 of [Fig.7]) can reduce the intensity of microneedling therapy or even stop it. microneedling therapy. In some embodiments, the combination of the moisture sensor 150 and the thermal sensor (and / or the thermal couple 165) is used to measure the transepidermal water loss (TEWL or TransEpidermal Water Loss) of a user.

[0044] In some embodiments, the applicator 100 (or an intelligent device, such as the intelligent device 200) has a pressure threshold. In some embodiments, if the pressure measured by the pressure sensor 160 exceeds the pressure threshold, the applicator 100 or an external device warns the user to reduce the pressure. In some embodiments, when the pressure exceeds the pressure threshold, the microneedling therapy is stopped. A chip (such as the chip 145) can collect one or more cartridge data points from the humidity sensor 150 and / or the temperature sensor 155 and compare these data points to a temperature and / or humidity threshold. In some embodiments, when the temperature and / or humidity reaches or exceeds the temperature and / or humidity threshold, the treatment is reduced.In this way, the 100 applicator can prevent a user from injuring themselves by applying microneedling therapy at an increased frequency and / or above the pressure threshold, temperature threshold and / or humidity threshold.

[0045] Figure 6 is an example of a treatment adjustment method 600 with a microneedle applicator, according to the present technology. In some embodiments, the method 600 is implemented or otherwise performed by the cartridges and / or applicators described herein. In some embodiments, the method 600 is performed by a cartridge (such as cartridge 125) having a microneedle plane (such as microneedle plane 130). In some embodiments, the microneedle plane includes one or more microneedles (such as one or more microneedles 175A, 175B, 175C... 175N). In some embodiments, the cartridge includes one or more sensors, such as humidity sensors, temperature sensors, pressure sensors, and the like, as described herein.In some embodiments, the cartridge further includes a chip (such as chip 145) configured to collect one or more cartridge data points from one or more sensors.

[0046] At block 605, the skin is brought into contact with the microneedle(s) plate of the applicator. In some embodiments, a pressure sensor (which may be part of the sensor system) detects pressure exerted on the skin. In some embodiments, the pressure data is transmitted to the applicator chip.

[0047] In block 610, the skin is prepared with one or more microneedles of the applicator. In some embodiments, the skin is penetrated to a depth not exceeding 5.0 mm. In some embodiments, the penetration The application of one or more microneedles to the skin is considered "microneedling therapy (or treatment)." In some embodiments, exfoliation without penetration of the skin is considered "microneedling therapy (or treatment)."

[0048] In block 615, one or more cartridge data points are measured using the sensor system (or one or more sensors) on the cartridge. In some embodiments, the one or more sensors include a temperature sensor, a pressure sensor, a humidity sensor, an optical sensor, and a combination thereof. In some embodiments, the data from each sensor are collected by the chip. In some embodiments, the one or more cartridge data points are a change in skin moisture, a cartridge pressure level, a change in skin temperature, a change in skin color, or a combination thereof.

[0049] In block 620, the chip adjusts the therapy treatment level based on one or more cartridge data points. In some embodiments, the one or more cartridge data points include pressure data, temperature data, optical data, and / or humidity data. Those skilled in the art should understand that many types of sensors measuring various types of sensors can be incorporated into the cartridge used to adjust the treatment level. In some embodiments, the treatment is applied at a treatment level selected from a plurality of treatment levels. In some embodiments, the chip is configured to decrease the treatment level when the one or more cartridge data points reach or exceed one or more thresholds, as explained in [Fig. 7].

[0050] Figure 7 is another example of a treatment adjustment method with a microneedle applicator, according to the present technology. In some embodiments, the method 700 is implemented or otherwise performed by the cartridges and / or applicators described herein. In some embodiments, the method 700 is performed by a cartridge (such as cartridge 125) having a microneedle surface (such as microneedle surface 130). In some embodiments, the microneedle surface includes one or more microneedles (such as one or more microneedles 175A, 175B, 175C... 175N). In some embodiments, the cartridge includes one or more sensors, such as humidity sensors, temperature sensors, pressure sensors, and the like, as described herein.In some embodiments, the cartridge further includes a chip (such as chip 145) configured to collect one or more cartridge data points from one or more sensors.

[0051] In block 705, one or more cartridge data points are compared to one or more thresholds. In some embodiments, the one or more thresholds include a pressure threshold, a temperature threshold, a humidity threshold, a color threshold, or a combination thereof. In some embodiments, the one or more sensors include a timer. In some embodiments, the one or more thresholds include a time threshold. In some embodiments, there is a threshold associated with each of the one or more sensors on the cartridge and / or applicator.

[0052] In decision block 710, it is determined whether one or more thresholds are met or exceeded. In some embodiments, if one or more thresholds are met, the process proceeds to block 715A. In some embodiments, a majority of one or more thresholds are met or exceeded so that the process proceeds to block 715A. In some embodiments, certain thresholds are weighted, meaning that certain thresholds are more likely to result in a determination that one or more thresholds have been met or exceeded. For example, in some embodiments, a pressure threshold may be weighted at a higher value than a color threshold. Consequently, if the pressure threshold is met or exceeded, the process proceeds to block 715A. In the same example, if the color threshold has been met or exceeded, the process may instead proceed to block 715B.A person skilled in the art should understand that thresholds can be weighted in any way. In some embodiments, such as when a timer is included in the cartridge and / or applicator, one or more thresholds can be determined to be reached when a certain duration has elapsed, such as 1 minute, 5 minutes, 15 minutes, or similar.

[0053] At block 715A, when one or more thresholds are reached or exceeded, the treatment level is reduced. In some embodiments, microneedle therapy is applied at a plurality of treatment levels. In some embodiments, the treatment levels correspond to a vibration level, the number of penetrations per millisecond of one or more microneedles, the penetration depth of one or more needles, or a combination thereof. For example, in some embodiments, a higher treatment level is a greater penetration depth of one or more microneedles, while a lower treatment level is a shallower penetration depth.Similarly, in another example, a higher processing level corresponds to a higher number of penetrations per millisecond, while a lower processing level corresponds to a lower number of penetrations per millisecond. This can also be applied when the processing does not involve penetration. For example, in some embodiments, the processing levels may be levels. exfoliation. In some embodiments, the lowest of the plurality of treatment levels is the shutdown of microneedling therapy. In some embodiments, such as when the applicator includes a timer, the microneedling therapy level can be reduced to the lowest level, so that microneedling therapy is stopped. In some embodiments, the applicator automatically adjusts the treatment level. In some embodiments, the applicator issues an alert to the user to adjust the treatment level with an actuator (such as actuator 115). In some embodiments, the alert is visual, audible, tactile, or a combination thereof.

[0054] Returning to decision block 710, if one or more thresholds are not reached, process 700 proceeds to block 715B. In some embodiments, one or more thresholds may be determined not to have been reached even if a threshold is reached, for example, when the thresholds are weighted. In other embodiments, if even one of the thresholds is reached, the process proceeds to block 715A.

[0055] At block 715B, the treatment level is maintained. The treatment level can be maintained until one or more thresholds are reached or exceeded. In some embodiments, a user turns off the applicator before one or more thresholds are reached.

[0056] It should be understood that processes 600 and 700 are to be interpreted as purely representative. In some embodiments, the process blocks of processes 600 and 700 may be carried out simultaneously, sequentially, in a different order, or even omitted, without departing from the scope of this disclosure.

[0057] This application may refer to quantities and numbers. Unless otherwise specified, these quantities and numbers are not to be considered restrictive, but rather representative of the possible quantities or numbers associated with this application. In this regard, this application may also use the term "plurality" to refer to a quantity or number. In this regard, the term "plurality" is understood to mean any number greater than one, for example, two, three, four, five, etc. The terms "about," "approximately," "close to," etc., mean plus or minus 5% of the stated value. For the purposes of this disclosure, the expression "at least one of A, B, and C," for example, means (A), (B), (C), (A and B), (A and C), (B and C), or (A, B, and C), including all other possible permutations when more than three items are listed.

[0058] The embodiments disclosed herein may employ circuitry to implement the technologies and methodologies described herein, connecting Functionally, two or more components, generate information, determine operating conditions, control an apparatus, device or process, and / or the like. Circuitry of any type may be used. In one embodiment, the circuitry includes, among other things, one or more computing devices such as a processor (e.g., a microprocessor), a central processing unit (CPU), a digital signal processor (DSP), an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or the like, or any combination thereof, and may include elements or electronics of separate digital or analog circuits, or combinations thereof.

[0059] An embodiment includes one or more data stores that, for example, store instructions or data. Non-limiting examples of one or more data stores include: volatile memory (e.g., random access memory (RAM), dynamic random access memory (DRAM), or the like), non-volatile memory (e.g., read-only memory (ROM), electrically erasable read-only memory (EEPROM), compact disc read-only memory (CD-ROM), or the like), persistent memory, or the like. Other non-limiting examples of one or more data stores include erasable and programmable read-only memory (EPROM), flash memory, or the like. One or more data stores may be connected, for example, to one or more computing devices by one or more instructions, data, or power buses.

[0060] In one embodiment, the circuitry includes a computer-readable media player or a memory slot configured to accept a signal-carrying medium (for example, computer-readable memory storage, computer-readable recording storage, or the like). In one embodiment, a program for causing a system to perform any of the disclosed processes may be stored, for example, on computer-readable recording storage (CRMM), a signal-carrying medium, or the like.Non-limiting examples of signal-carrying media include recordable media such as any form of flash memory, magnetic tape, floppy disk, hard drive, compact disc (CD), digital video disc (DVD), Blu-ray disc, digital tape, computer memory, or the like, as well as transmission media such as digital and / or analog communication media (e.g., fiber optic cable, waveguide, wired communication link, wireless communication link) (e.g., transmitter, receiver, transceiver, transmission logic, receiving logic, etc.). Other non-limiting examples of signal-carrying media include, but are not limited to, DVD-ROM, DVD-RAM, DVD+RW, DVD-RW, DVD-R, DVD+R, CD-ROM, Super Audio CD, CD-R, CD+R, CD+RW, CD-RW, video compact discs, and discs. super video, flash memory, magnetic tape, magneto-optical disc, MINIDISC, non-volatile memory card, EEPROM, optical disc, optical storage, RAM, ROM, system memory, web server, or similar.

[0061] The detailed description presented above in relation to the accompanying drawings, where similar numbers refer to similar elements, is intended as a description of various embodiments of this disclosure and is not intended to represent the only embodiments. Each embodiment described in this disclosure is offered solely by way of example or illustration and should not be construed as being preferred or advantageous over other embodiments. The illustrative examples provided herein are not intended to be exhaustive or to limit the disclosure to the specific forms disclosed. Similarly, all the steps described herein may be interchangeable with other steps, or combinations of steps, to achieve the same or substantially similar result.In general, the embodiments disclosed here are not limiting, and the inventors contemplate that other embodiments within the scope of this disclosure may include structures and functionalities from more than one specific embodiment illustrated in the Figures and described in the memorandum.

[0062] In the preceding description, specific details are presented to provide a thorough understanding of the example embodiments of this disclosure. However, it will be apparent to a person skilled in the art that the embodiments disclosed herein can be implemented without incorporating all the specific details. In some cases, well-known process steps have not been described in detail so as not to unnecessarily obscure various aspects of this disclosure. Furthermore, it should be appreciated that the embodiments of this disclosure may employ any combination of features described herein.

[0063] This application may include references to directions, such as "vertical", "horizontal", "front", "back", "left", "right", "above" and "below", etc. These references, and other similar references in this application, are intended to help describe and understand the particular embodiment (such as when the embodiment is positioned for use) and are not intended to limit this disclosure to those directions or locations.

[0064] This application may also refer to quantities and numbers. Unless specifically stated, these quantities and numbers shall not be considered restrictive but rather as examples of the possible quantities or numbers associated with this application. In this respect also, this application may use the term "plurality" to refer to a quantity or number. In this respect, the term "plurality" is understood to mean any number greater than one, for example, two, three, four, five, etc. The terms "about," "approximately," etc., mean to within plus or minus 5% of the stated value. The term "based on" means "based at least partially on".

[0065] The principles, representative embodiments, and modes of operation of this disclosure have been described in the preceding description. However, aspects of this disclosure that are intended to be protected should not be interpreted as being limited to the particular embodiments disclosed. Furthermore, the embodiments described herein should be considered illustrative rather than restrictive. It should be understood that variations and changes may be made by other means, and equivalents may be used, without departing from the spirit of this disclosure. Accordingly, it is expressly intended that all such variations, changes, and equivalents fall within the spirit and scope of this disclosure as claimed.

[0066] Although illustrative embodiments have been shown and described, it will be appreciated that various changes can be made to them without departing from the spirit and scope of the invention.

Claims

Demands

1. Skin treatment cartridge (125), comprising: a microneedle(s) plane (130) including one or more microneedle(s), configured to prepare the skin for treatment; one or more sensors configured to measure one or more cartridge data points; and a chip (145) configured to collect one or more cartridge data points and modulate the treatment based on one or more data points.

2. Cartridge according to claim 1, wherein the chip (145) is a near field communication (NFC) tag.

3. Cartridge according to claim 1, wherein the chip (145) is a microcontroller unit (MCU) tag or an optical recognition sensor.

4. Cartridge according to any one of claims 1 to 3, wherein the cartridge further comprises a tip (135) configured to cover one or more microneedles.

5. Cartridge (125) according to any one of claims 1 to 4, wherein one or more sensors are a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof.

6. Cartridge (125) according to any one of claims 1 to 5, wherein one or more cartridge data items are a change in skin moisture, a cartridge pressure level, a change in skin temperature, a change in skin color, or any combination thereof.

7. Cartridge (125) according to any one of claims 1 to 6, wherein the treatment is applied to a treatment level selected from a plurality of treatment levels.

8. Cartridge according to any one of claims 1 to 7, wherein the chip (145) is configured to decrease the processing level when one or more cartridge data reaches or exceeds one or more thresholds.

9. Applicator (100) comprising: a cartridge (125) configured to removably couple to the applicator, comprising: a microneedle(s) plan (130) including one or more microneedle(s), configured to prepare the skin for providing treatment; one or more sensors configured to measure one or more cartridge data points; and a chip (145) configured to collect one or more cartridge data points and modulate the processing according to one or more cartridge data points.

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