Use of peptide amide compound in preparation of drug for preventing nausea and vomiting

Peptide amide compounds are used to prepare medicaments that effectively prevent postoperative and chemotherapy-induced nausea and vomiting, overcoming the inadequacies of existing treatments.

HK40135217APending Publication Date: 2026-07-17HAISCO PHARMACEUTICAL GROUP CO LTD
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Patent Information

Authority / Receiving Office
HK · HK
Patent Type
Applications
Current Assignee / Owner
HAISCO PHARMACEUTICAL GROUP CO LTD
Filing Date
2026-06-10
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing treatments for postoperative nausea and vomiting (PONV) and chemotherapy-induced nausea and vomiting (CINV) are inadequate in efficacy and specificity, lacking targeted therapeutic options.

Method used

The use of peptide amide compounds, including their stereoisomers, hydrates, metabolites, solvates, pharmaceutically acceptable salts, and cocrystals, in the preparation of medicaments to prevent PONV and CINV.

Benefits of technology

The peptide amide compounds provide targeted and effective prevention of nausea and vomiting, addressing the limitations of current therapies.

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Abstract

Use of a compound of formula (I) or its stereoisomer, hydrate, metabolite, solvate, pharmaceutically acceptable salt, co-crystal or a composition thereof, in the manufacture of a medicament for preventing postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting.
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Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202480064782.7 (22) Application Date 2024.10.09 (66) Domestic Priority Data 202311305170.6 2023.10.10 CN 202410544545.2 2024.05.06 CN 202411022811.1 2024.07.29 CN (85) PCT International Application Entering National Phase Date 2026.04.09 (86) PCT International Application Application Data PCT / CN2024 / 123615 2024.10.09 (87) PCT International Application Publication Data WO2025 / 077727 ZH 2025.04.17 (71) Applicant: Hisun Pharmaceutical Group Co., Ltd. Address: No. 43, Wenxiong Avenue, Naidong District, Shannan City, Tibet Autonomous Region, 856099 (72) Inventors: Cao Yong, Zhao Wanyun, Li Yanjun, Chen Wei (74) Patent Agency: Beijing Sanyou Intellectual Property Agency Co., Ltd. 11127 Patent Agent: Zhang Debin, Han Lei (51) Int.Cl. A61K 38 / 07 (2006.01) C07K 5 / 107 (2006.01) A61P 1 / 08 (2006.01) (54) Invention Name: Use of peptide amide compounds in the preparation of medicaments for the prevention of nausea and vomiting (57) Abstract: Use of the compound or its stereoisomers, hydrates, metabolites, solvates, pharmaceutically acceptable salts, cocrystals or combinations thereof in the preparation of medicaments for the prevention of postoperative nausea and vomiting or nausea and vomiting caused by chemotherapy. CN 122121889 A 2026.05.29 CN 1 22 12 18 89 A