Cosmetics

Abstract

We provide cosmetics with an excellent user experience. [Solution] A cosmetic comprising (A) a glycine derivative having a specific structure or a salt thereof, (B) a polyglycerin fatty acid ester, and (C) water.

Description

[Technical Field]

[0001] This invention relates to cosmetics. Specifically, this invention relates to cosmetics comprising a glycine derivative or a salt thereof. [Background technology]

[0002] Glycine derivatives or salts thereof are known to have a pore-reducing effect (for example, Patent Document 1) and are included in various cosmetics. In order to more strongly express the effect obtained by glycylglycine, it is conceivable to increase its content, but according to the inventors' research, it has been found that simply increasing the content of glycylglycine in a cosmetic tends to cause stickiness after application. For this reason, there is a need for a cosmetic containing a glycine derivative or salt thereof that can achieve excellent usability even at a high content. [Prior art documents] [Patent Documents]

[0003] [Patent Document 1] Patent No. 5241058 [Overview of the Initiative]

[0004] The inventors have surprisingly discovered that a cosmetic composition containing a combination of a glycine derivative or salt thereof having a specific structure and a polyglycerol fatty acid ester suppresses stickiness, provides a smooth feel, and offers a moist feel, and that this effect is maintained even when the glycylglycine content is high. The present invention is based on these findings.

[0005] The following inventions are provided according to this disclosure. [1](A) Below formula (1): [ka] (In the formula, R 1 and R 2 Each of these is independently a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group. R 3 These are a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, R 1 , R 2 , and R 3 (They cannot simultaneously become hydrogen atoms.) A glycine derivative or salt thereof represented by (B) Polyglycerol fatty acid esters, and (C) Water; Cosmetics containing the following ingredients. [2] The cosmetic composition according to [1], wherein the content of component (A) is 0.01% by mass or more and 7% by mass or less with respect to the total amount of the cosmetic composition. [3] The cosmetic composition according to [1] or [2], wherein component (A) contains glycylglycine. [4] The cosmetic composition according to any one of [1] to [3], wherein the number of carbon atoms in the fatty acid portion of the polyglycerin fatty acid ester is 12 or more and 17 or less. [5] The cosmetic composition according to any one of [1] to [4], wherein the polyglycerin portion of the polyglycerin fatty acid ester is in the form of a dimer or more and a decamer or less. [6](B) A cosmetic product according to any one of [1] to [5], comprising polyglyceryl-6 laurate or polyglyceryl-6 myristate. [7](B) The cosmetic composition described in any one of [1] to [6], wherein the content of component (B) is 0.1% by mass or more and 10% by mass or less based on the total amount of the cosmetic composition. [8](D) A cosmetic composition according to any one of [1] to [7], wherein the oil content is 0% by mass or more and 40% by mass or less, based on the total amount of the cosmetic composition. [9] A cosmetic product according to any one of [1] to [8], which is an aqueous cosmetic product or an oil-in-water emulsion cosmetic product.

[0006] According to the present invention, a cosmetic excellent in the feeling of use can be provided. In particular, a cosmetic can be provided which suppresses stickiness after application and gives a smooth feeling of use during application and a moist feeling of use after application. Specific description of the invention

[0007] The present invention relates to a cosmetic comprising (A) a glycine derivative having a specific structure or a salt thereof, (B) a polyglyceryl fatty acid ester, and (C) water. Hereinafter, the components that can be contained in the cosmetic of the present invention will be described.

[0008] (A) Glycine derivative or its salt The cosmetic according to the present invention comprises (A) a glycine derivative represented by formula (1) or a salt thereof (hereinafter sometimes referred to as component (A). The same applies to other components). [Chemical formula] In the formula, R 1 and R 2 are each independently a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group. Preferably, either one of R 1 and R 2 is a hydrogen atom and the other is a methyl group, an aminomethylcarbonyl group, or a benzylcarbonyl group. R 3 is a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group, preferably a hydrogen atom or a methyl group. However, R 1 and R 2 and R 3 will not simultaneously become hydrogen atoms.

[0009] (A) component may be a salt of a glycine derivative represented by formula (1). The type of salt is not particularly limited as long as it is a pharmaceutically acceptable salt. For example, hydrochloride, sulfate, phosphate, hydrobromide, sodium salt, potassium salt, magnesium salt, calcium salt, magnesium salt, ammonium salt, etc. may be mentioned. Examples of organic salts include acetate, lactate, maleate, fumarate, tartrate, methanesulfonate, p-toluenesulfonate, triethanolamine salt, amino acid salt, etc. (A) component preferably contains glycylglycine.

[0010] (A) component can be blended with one or more kinds. The content of (A) component is preferably 0.01% by mass or more, 0.05% by mass or more, or 0.3% by mass or more, and preferably 7% by mass or less, 5% by mass or less, or 3% by mass or less with respect to the total amount of the cosmetic. In addition, when the (A) component is contained in the cosmetic at 1% by mass or more, the user can feel the effect of shrinking pores, which is more preferable.

[0011] (B) Polyglycerin fatty acid ester Polyglycerin fatty acid ester can be prepared by esterifying a fatty acid and polyglycerin. Here, in polyglycerin fatty acid ester, the part derived from the fatty acid is called the fatty acid part, and the part derived from polyglycerin is called the polyglycerin part. The fatty acid part has lipophilicity, and the polyglycerin part has hydrophilicity. Polyglycerin fatty acid ester may form vesicles which are bimolecular film-closed bodies encapsulating other components in the cosmetic. Oil can be retained in the bimolecular film of the vesicles.

[0012] ​​The number of carbon atoms in the fatty acid portion of the polyglycerol fatty acid ester is preferably 12 or more, 13 or more, or 14 or more, and preferably 17 or less, 16 or less, or 15 or less. The fatty acid may be a saturated fatty acid or an unsaturated fatty acid, and may be a straight-chain fatty acid or a branched-chain fatty acid. Examples of such fatty acids include lauric acid, myristic acid, and palmitic acid. Lauric acid or myristic acid are preferred as the fatty acid.

[0013] The polyglycerin portion of the polyglycerin fatty acid ester is preferably a dimer or more, a triper or more, or a quadrimer or more, and more preferably a decumer or less, a numericer or less, an octomer or less, a heptomer or less, or a hexamer or less.

[0014] The OH / C ratio of the polyglycerin fatty acid ester is preferably 0.20 or higher, 0.25 or higher, 0.30 or higher, 0.35 or higher, 0.40 or higher, 0.45 or higher, or 0.50 or higher, and more preferably 0.80 or lower, 0.75 or lower, 0.70 or lower, 0.65 or lower, or 0.60 or lower. Polyglycerin fatty acid esters having such an OH / C ratio are preferred because they can improve the solubilizing ability of the oil in vesicles when vesicles are formed.

[0015] Here, in this disclosure, "OH / C ratio" means the ratio of the number of hydroxyl groups in the polyglycerin portion to the number of carbon atoms in the fatty acid portion. The OH / C ratio is also a parameter related to the balance between hydrophilicity and lipophilicity. For example, in the case of polyglyceryl-6 laurate, the fatty acid portion has 12 carbon atoms. The polyglycerin portion is a hexamer, and in that case, there are 7 hydroxyl groups (=6+1). Therefore, the OH / C ratio of polyglyceryl-6 laurate is 0.58 (=7 / 12). In the case of polyglyceryl-6 myristate, the fatty acid portion has 14 carbon atoms. The polyglycerin portion is a hexamer, and in that case, there are 7 hydroxyl groups (=6+1). Therefore, the OH / C ratio of polyglyceryl-6 laurate is 0.50 (=7 / 14).

[0016] Polyglycerin fatty acid esters are preferably polyglycerin mono fatty acid esters. Specifically, examples of polyglycerin fatty acid esters include polyglyceryl-6 myristate, polyglyceryl-2 laurate, polyglyceryl-4 laurate, polyglyceryl-5 laurate, polyglyceryl-6 laurate, and polyglyceryl-10 palmitate. Component (B) preferably contains polyglyceryl-6 laurate or glyceryl-6 myristate.

[0017] (B) The content of component (B) may be 0.1% by mass or more, 0.2% by mass or more, or 0.3% by mass or more, relative to the total amount of the cosmetic, and may also be 10% by mass or less, 5.0% by mass or less, or 3.0% by mass or less.

[0018] (C)Water The cosmetic composition according to the present invention comprises (C) water. As the water, water used for cosmetics, quasi-drugs, etc., can be used, for example, purified water, ion-exchanged water, tap water, etc. The water content is preferably 40% by mass or more, or preferably 50% by mass or more, and preferably 95% by mass or less, or 90% by mass or less, based on the total amount of the cosmetic composition according to the present invention.

[0019] The cosmetic composition of the present invention may contain (D) oil in addition to (A) to (C). In such cases, the cosmetic composition of the present invention generally takes the form of an oil-in-water cosmetic or a water-in-oil cosmetic, but may also be a two-layer cosmetic that separates into two layers when left to stand.

[0020] (D) Oil (D) Examples of oils include ester oils, silicone oils, hydrocarbon oils, higher fatty acids, higher alcohols, liquid oils, solid oils, and semi-solid oils. Preferably, the oil is an ester oil, silicone oil, hydrocarbon oil, or higher alcohol. One or more types of (D) components may be blended. When the cosmetic is an oil-in-water emulsion cosmetic, the content of (D) components is preferably 0.5% by mass or more, or 1% by mass or more, and preferably 40% by mass or less, or 30% by mass or less, based on the total amount of the cosmetic. When the cosmetic is an aqueous cosmetic, the content of (D) components is preferably 0% by mass or more, and 1% by mass or less.

[0021] Examples of ester oils include octyl octanoate, nonyl nonanoate, cetyl octanoate, isopropyl myristate (isopropyl myristate), octyldodecyl myristate, isopropyl palmitate, ethylhexyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, and isocetyl isostearate. , 12-Hydroxystearate Cholesteryl, Di-2-Ethylhexanoate Ethylene Glycol, Dipentaerythritol Fatty Acid Ester, N-Alkyl Glycol Monoisostearate, Neopentyl Glycol Dicaprate, Tripropylene Glycol Pivalate, Diisostearyl Malate, Glyceryl Di-2-Heptyl Undecanoate, Glyceryl Diisostearate, Trimethylolpropane Tri-2-Ethylhexanoate, Trimethylolpropane Triisostearate Pentaerythritol tetra-2-ethylhexanoate, glyceryl tri-2-ethylhexanoate, glyceryl trioctanoate, glyceryl triisopalmitate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate-2-ethylhexyl palmitate, glyceryl trimyristate, glyceride tri-2-heptylundecanoate, methyl castor oil fatty acid ester, oleyl oleate, acetoglyceride, 2-heptylun palmitate Examples include decyl, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, di-2-heptylundecyl adipate, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate, triethyl citrate, cetyl ethylhexanoate, and macadamia nut fatty acid phytosteryl.

[0022] Examples of silicone oils include linear polysiloxanes (e.g., dimethicone, diphenylsiloxyphenyl trimethicone, diphenylpolysiloxane, etc.), cyclic polysiloxanes (e.g., octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, etc.), silicone resins forming a three-dimensional network structure, silicone rubber, various modified polysiloxanes (amino-modified polysiloxane, polyether-modified polysiloxane, alkyl-modified polysiloxane, fluorine-modified polysiloxane, etc.), acrylic silicones, etc., with linear polysiloxane being preferred.

[0023] Examples of hydrocarbon oils include isododecane, isohexadecane, isoparaffin, mineral oil (liquid paraffin), ozokerite, squalane, pristane, paraffin, ceresin, squalene, petrolatum, microcrystalline wax, and hydrogenated polydecene.

[0024] Examples of high-grade fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, undecylenic acid, tallic acid, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

[0025] Examples of higher alcohols include straight-chain alcohols (e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol, etc.) and branched-chain alcohols (e.g., lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, octyldodecanol, etc.).

[0026] Examples of liquid oils include avocado oil, camellia oil, macadamia nut oil, corn oil, olive oil, rapeseed oil, sesame oil, peach kernel oil, wheat germ oil, sasanqua oil, castor oil, linseed oil, safflower oil, cottonseed oil, elm oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, cinnamon oil, Japanese tuni oil, jojoba oil, germ oil, and triglycerin. Examples of solid oils include cocoa butter, coconut oil, hydrogenated coconut oil, palm oil, palm kernel oil, hydrogenated palm oil, Japanese wax kernel oil, hydrogenated oil, Japanese wax, and hydrogenated castor oil. Examples of semi-solid oils include shea butter, partially hydrogenated coconut oil, and partially hydrogenated jojoba oil.

[0027] Furthermore, the cosmetic composition of the present invention may further contain polyhydric alcohols. Examples of polyhydric alcohols include glycerin, ethylene glycol, propylene glycol, 1,3-butylene glycol, dipropylene glycol, polyethylene glycol, polypropylene glycol, and polybutylene glycol. Among these, the cosmetic composition of the present invention preferably contains dipropylene glycol or 1,3-butylene glycol. Polyhydric alcohols can be used alone or in combination of two or more. However, the content of polyhydric alcohols is preferably 1% by mass or more, 2% by mass or more, or 5% by mass or more, and preferably 30% by mass or less, 25% by mass or less, or 20% by mass or less, based on the total amount of the cosmetic composition.

[0028] Furthermore, the cosmetic composition of the present invention may further contain a thickening agent. As a thickening agent, (i) Water-soluble thickeners, such as plant-derived polymers like gum arabic, tragacanth gum, galactan, carob gum, guar gum, karaya gum, carrageenan, pectin, agar, quince seed (quince), algae colloid (brown algae extract); microbial polymers like dextran, succinoglucan, pullulan, xanthan gum; animal-derived polymers like collagen, casein, albumin, gelatin; cellulosic polymers like methylcellulose, nitrocellulose, ethylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, sodium cellulose sulfate, hydroxypropylcellulose, sodium carboxymethylcellulose, crystalline cellulose, cellulose powder; alginate polymers like sodium alginate, propylene glycol alginate; vinyl polymers like polyvinyl alcohol, polyvinyl methyl ether, polyvinylpyrrolidone, carboxyvinyl polymer (carbomer); polyoxyethylene polymers like hydrophobic modified polyether urethane; acrylic polymers like sodium polyacrylate, polyethyl acrylate, polyacrylamide, polyethyleneimine, cationic polymers, (ii) Inorganic water-soluble polymers, such as bentonite, magnesium aluminum silicate, laponite, hectorite, anhydrous silicic acid, etc. These can be listed as examples. Thickening agents can be used alone or in combination of two or more types.

[0029] The content of the thickening agent is preferably 0.01% by mass or more, 0.05% by mass or more, or 0.1% by mass or more, and preferably 1.5% by mass or less, 1.0% by mass or less, or 0.8% by mass or less, based on the total amount of the cosmetic composition.

[0030] Furthermore, the cosmetic composition of the present invention may further contain a surfactant. The type of surfactant is arbitrary, but it is preferable to include an anionic surfactant.

[0031] Examples of anionic surfactants include N-acyl amino acid salts and N-acyl methyl taurate salts. Specifically, examples include N-acyl glutamates such as potassium cocoyl glutamate, N-acyl-N-methyl-β-alanine salts, N-acyl sarcosinate salts, sodium N-cocoyl taurate, sodium N-cocoyl-N-methyl taurate, sodium N-lauroyl-N-methyl taurate, sodium N-stearoyl-N-methyl taurate, sodium N-coconut oil fatty acid-N-methyl taurate, sodium N-coconut oil fatty acid-N-methyl taurate, N-coconut oil fatty acid-N-methyl taurate triethanolamine, N-palm oil fatty acid-N-ethyl taurate triethanolamine, magnesium N-cocoyl taurate, magnesium N-cocoyl-N-methyl taurate, magnesium N-lauroyl-N-taurate, magnesium N-lauroyl-N-methyl taurate, and magnesium N-coconut oil fatty acid-N-methyl taurate. Of these, the cosmetic composition of the present invention preferably contains sodium cocoyl methyl taurate and sodium N-stearoyl-N-methyl taurate. The anionic surfactants can be used alone or in combination of two or more.

[0032] The content of the anionic surfactant is preferably 0.01% by mass or more, 0.03% by mass or more, 0.05% by mass or more, or 0.07% by mass or more, relative to the total amount of the cosmetic composition, and is also preferably 1.0% by mass or less, 0.7% by mass or less, 0.5% by mass or less, or 0.3% by mass or less.

[0033] In addition to the above-mentioned components, the cosmetic composition of the present invention may contain any other components commonly used in cosmetics and pharmaceuticals. These optional components include, for example, surfactants, humectants, lower alcohols, metal ion chelating agents, neutralizing agents, pH adjusters, antioxidants, preservatives, pharmaceuticals, UV absorbers, powder components, fragrances, and the like. One or more of these optional components may be incorporated into the cosmetic composition as long as they achieve the effects of the present invention.

[0034] The cosmetic composition of the present invention provides a smooth feel during application. Furthermore, in the cosmetic composition of the present invention, as the content of component (A) increases, the stickiness of the cosmetic composition is suppressed while enhancing the moist feeling after application.

[0035] The dosage form of the cosmetic composition according to the present invention is not particularly limited, but it is preferably in the form of an aqueous cosmetic or an oil-in-water emulsion cosmetic. In aqueous cosmetic or oil-in-water emulsion cosmetic, the aqueous phase comes into contact with the skin first, giving the skin a fresh feeling and making it possible to more fully experience the effects of the present invention.

[0036] Examples of cosmetics according to the present invention include skincare cosmetics (e.g., lotions, emulsions, creams, serums, packs, masks, etc.), makeup cosmetics (e.g., foundations, makeup bases, etc.), skin cleansing products (e.g., facial cleansers, makeup removers, etc.), and sunscreen cosmetics. These forms are merely examples, and the cosmetics according to the present invention are not limited to these forms. Furthermore, the cosmetic composition according to the present invention can be manufactured by conventional methods. [Examples]

[0037] The present invention will be specifically described based on the following examples, but the present invention is not limited to these examples. Unless otherwise specified, the content is expressed as mass % of the total amount.

[0038] [Examples 1-5 and Comparative Examples 1-3] Oil-in-water emulsion cosmetics for Reference Example 1, Reference Example 2, Examples 1-5, and Comparative Examples 1-3 were prepared using the formulations shown in Table 1.

[0039] [Usability Evaluation 1: Smoothness] Cosmetics prepared with the formulations shown in Table 1 were applied to the skin by a panel of five experts, and their usability was evaluated based on the following criteria regarding smoothness during application. Smoothness during application means that no resistance or dragging is felt on the skin during application. The results obtained are shown in Table 1 or 2. A: All five individuals assessed that there was no change compared to the standard. B: 1-2 people reported feeling resistance during application compared to the standard. C: Three or more users reported feeling resistance during application compared to the standard.

[0040] [Ease of Use Evaluation 2: Non-stickiness] Cosmetics prepared with the formulations shown in Table 1 were applied to the skin by a panel of five experts, who evaluated the lack of stickiness after application. The results are shown in Table 1 or 2. A: All five individuals assessed that there was no change compared to the standard. B: 1-2 people reported feeling sticky after application compared to the standard. C: Three or more people rated the product as feeling sticky after application compared to the standard.

[0041] [Ease of Use Evaluation 3: Moisture] Cosmetics prepared with the formulations shown in Table 1 were applied to the skin by a panel of five experts, and the moisturizing effect after application was evaluated. The results obtained are shown in Table 1 or 2. 2:3 or more people rated the product as feeling more moisturized after application compared to the standard. 1 to 2 people rated the product as feeling more moisturized after application compared to the standard. 0: All 5 people evaluated it as no change from the standard.

[0042] Furthermore, in usability evaluations 1-3, Reference Example 1, which does not contain component (A) but contains component (B), was compared with Examples 1-5, which each contained component (A) in different concentrations and also contained component (B). In addition, Reference Example 2, which does not contain component (A) but contains PEG-6 distearate instead of component (B), was compared with Comparative Examples 1-3, which each contained component (A) in different concentrations and also contained PEG-6 distearate. [Table 1]

[0043] [Examples 6-8 and Comparative Examples 4-6] Aqueous cosmetic compositions for Reference Example 3, Reference Example 4, Examples 6-8, and Comparative Examples 4-6 were prepared using the formulations shown in Table 2. Usability evaluations 1-3 were conducted using the same criteria as for Examples 1-5 and Comparative Examples 1-3. The results obtained are shown in Table 2.

[0044] Furthermore, in usability evaluations 1-3, Reference Example 3, which does not contain component (A) but contains component (B), was compared with Examples 6-8, which each contained component (A) at different concentrations and also contained component (B). In addition, Reference Example 4, which does not contain component (A) but contains PPG-13 decyltetradeceth-24 instead of component (B), was compared with Comparative Examples 4-6, which each contained component (A) at different concentrations and also contained PPG-13 decyltetradeceth-24. [Table 2]

Claims

1. (A) The following formula (1): 【Chemistry 1】 (In the formula, R １ and R ２ Each of these is independently a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group. R ３ These are a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, R １ , R ２ , and R ３ (They cannot simultaneously become hydrogen atoms.) A glycine derivative or salt thereof represented by (B) Polyglycerol fatty acid ester, and (C) water; Cosmetics containing the following ingredients.

2. (A) The cosmetic composition according to claim 1, wherein the content of component is 0.01% by mass or more and 7% by mass or less with respect to the total amount of the cosmetic composition.

3. (A) The cosmetic composition according to claim 1 or 2, wherein component (A) contains glycylglycine.

4. The cosmetic composition according to claim 1 or 2, wherein the number of carbon atoms in the fatty acid portion of the polyglycerin fatty acid ester is 12 or more and 17 or less.

5. The cosmetic composition according to claim 1 or 2, wherein the polyglycerin portion of the polyglycerin fatty acid ester is a dimer or more and a decamer or less.

6. (B) The cosmetic composition according to claim 1 or 2, wherein component (B) comprises polyglyceryl-6 laurate or polyglyceryl-6 myristate.

7. The cosmetic composition according to claim 1 or 2, wherein the content of component (B) is 0.1% by mass or more and 10% by mass or less with respect to the total amount of the cosmetic composition.

8. (D) The cosmetic composition according to claim 1 or 2, wherein the oil content is 0% by mass or more and 40% by mass or less with respect to the total amount of the cosmetic composition.

9. The cosmetic composition according to claim 1 or 2, which is an aqueous cosmetic composition or an oil-in-water emulsion cosmetic composition.

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