compound
Substituted benzimidazole dimers modulate STING activity to treat or prevent diseases by inducing type I interferons and enhancing immune responses, effectively addressing the limitations of current treatments for autoimmune diseases, allergic diseases, infectious diseases, cancer, and precancerous syndromes, and serving as vaccine adjuvants.
JP2026116400APending Publication Date: 2026-07-09CTXT PTY LTD
Patent Information
- Application Number
- JP2026073864
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2020-06-30
- Filing Date
- 2026-04-27
- Publication Date
- 2026-07-09
Smart Images
Figure 2026116400000001 
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Figure 2026116400000003
Abstract
To provide compounds. [Solution] This disclosure relates to a compound of formula (I) which is a modulator of STING. Also disclosed are pharmaceutical compositions comprising a compound of formula (I), and methods of using a compound of formula (I) in the treatment or prevention of a disease improved by the modulation of STING. In one embodiment, the present invention provides a compound of the present invention for use in therapy. The present invention also provides a compound of formula I or a pharmaceutically acceptable salt thereof for use in therapy. In particular, the present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof for use in the treatment of STING-mediated diseases or disorders.
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Citation Information
Patent Citations
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