Nicotine pouch filler and method for manufacturing the same

Abstract

The present invention relates to a nicotine pouch filler comprising nicotine, a release-controlling excipient, a binder, a pH adjuster, and a flavoring, wherein the content of the binder is 6 to 10% by weight relative to the total solid contents of the nicotine pouch filler.

Claims

1. nicotine, Release-controlled excipients, Binder, pH adjusters, and Contains fragrances, The content of the binder is 6 to 10% by weight relative to the total solid contents of the nicotine pouch filler, in a nicotine pouch filler.

2. The nicotine pouch filler according to claim 1, wherein the binder comprises at least one selected from the group consisting of povidone K-25, hydroxypropyl cellulose, low-substituted hydroxypropyl cellulose, hydroxypropyl methylcellulose (HPMC), and carboxymethylcellulose (CMC).

3. Nicotine contains nicotine salts, The nicotine pouch filler according to claim 1, wherein the nicotine salt comprises at least one selected from the group consisting of nicotine salt benzoate, nicotine salt tartrate, nicotine salt malate, and nicotine salt salicylate.

4. The nicotine pouch filler according to claim 1, wherein the release-controlling excipient comprises one or more selected from the group consisting of cellulose and sugar alcohols.

5. The nicotine pouch filler according to claim 4, wherein the cellulose is one or more of microcrystalline cellulose and methylcellulose.

6. The nicotine pouch filler according to claim 4, wherein the sugar alcohol comprises at least one selected from the group consisting of erythritol, xylitol, mannitol, sorbitol, maltitol, and isomalt.

7. The nicotine pouch filling agent according to claim 1, wherein the pH adjusting agent is at least one selected from the group consisting of sodium bicarbonate and sodium carbonate.

8. The nicotine pouch filler according to claim 1, wherein the pH of the nicotine pouch filler is 8.3 to 8.

5.

9. The nicotine pouch filler according to claim 1, wherein the nicotine pouch filler contains particles having a size of 150 to 300 μm.

10. The nicotine pouch filler according to claim 1, wherein the nicotine pouch filler can have a nicotine dissolution performance of 20% or more within 8 minutes and a nicotine dissolution performance of 70% or more within 30 minutes.

11. Nicotine pouch filler, and Including packaging materials, The aforementioned nicotine pouch filler is nicotine, Release-controlled excipients, Binder, pH adjusters, and Contains fragrances, The content of the binder is 6 to 10% by weight relative to the weight of the solid content of the nicotine pouch filler, in a nicotine pouch.

12. Step S1 involves mixing at least one selected from the group consisting of nicotine, release-controlling excipients, binders, pH adjusters, and flavorings. Step S2 involves spraying the solvent, and The step includes granulation step S3, A method for producing a nicotine pouch filler, wherein in step S1, the content of the binder is 6 to 10% by weight relative to the solid content weight of the nicotine pouch filler.

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