Benzofuran derivatives as SIK inhibitors and their use

Abstract

A compound of formula (I), as well as its composition and method of use, is provided, wherein the variable R 1 , R 2 , R 5 , X, X 1 , and X 2 The values ​​are provided herein. The compound inhibits salt-inducible kinase activity and is useful in the treatment of various inflammatory diseases. Disclosure herein provides salt-inducible kinase inhibitors, as well as compositions and methods of use thereof. In the first embodiment, disclosed herein is a benzofuran derivative of formula (I). JPEG2026520705000427.jpg36165

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