Cleaning composition and cleaning aerosol product

Abstract

To provide a cleaner composition that is excellent in all effects of disinfection, virus inactivation and urolith removal, and an aerosol product for cleaning containing the same.SOLUTION: According to an embodiment, a cleaner composition for toilets containing a silver complex, lactic acid, and a surfactant is provided.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a cleaning composition and a cleaning aerosol product. [Background technology]

[0002] It is known that silver compounds are used as antibacterial agents in cleaning agents for hard surfaces such as toilet bowl surfaces. However, silver compounds are generally prone to deterioration due to exposure to light, and many of them have low water solubility, so that it is difficult to obtain the desired disinfecting effect at low concentrations when used in cleaning agents.

[0003] It is also known that urinary stones, which are formed when phosphates, calcium salts, uric acid, etc. in urine are decomposed by enzymes and become poorly soluble compounds, tend to accumulate on the surface of the toilet. When urinary stones accumulate, they cause yellowing and also create an environment in which microorganisms such as bacteria and fungi (mold, etc.) tend to grow, causing bad odors. Since urinary stones are alkaline stains, acidic toilet cleaners have been proposed to solve this problem. For example, Patent Document 1 discloses an aerosol-type toilet rim cleaner that includes an acidic cleaner containing glycolic acid as a urinary stone decomposition component and a metal aerosol container filled with a propellant. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] JP 2012-21035 A Summary of the Invention [Problem to be solved by the invention]

[0005] Although the use of urinary stone decomposition components such as glycolic acid can remove urinary stones, it is insufficient to achieve a disinfecting effect on the entire toilet surface. And, as mentioned above, even if a silver compound is blended as an antibacterial agent at a low concentration, the desired disinfecting effect cannot be obtained. In addition, in order to prevent infection with norovirus, influenza virus, etc., it is also desired that the cleaning agent has an excellent virus inactivation effect.

[0006] An object of the present invention is to provide a cleaning composition which is excellent in all of the disinfecting effect, virus inactivation effect and urinary stone removal effect, and to provide a cleaning aerosol product containing the same. [Means for solving the problem]

[0007] As a result of extensive investigations aimed at solving the above problems, the present inventors discovered that the above problems could be solved by using a combination of a silver complex, lactic acid, sodium lactate, and a surfactant, and thus completed the present invention.

[0008] The present invention is, for example, as follows. [1] A cleaning composition comprising a silver complex, lactic acid, and a surfactant.

[0009] [2] The cleaning composition according to [1], comprising, as the silver complex, one or more complexes selected from the group consisting of a complex of silver and an amino acid, a complex of silver and a carboxylic acid, a complex of silver and a carboxylic acid and an amino acid, and a complex of silver and an imidazole derivative.

[0010] [3] The cleaning composition according to [1] or [2], wherein the silver complex comprises at least a complex of silver, a carboxylic acid, and creatinine.

[0011] [4] The cleaning composition according to any one of [1] to [3], containing, as the surfactant, a polyoxyethylene alkyl ether and / or a polyoxyethylene alkyl ether sulfate.

[0012] [5] The cleaning composition according to any one of [1] to [4], further comprising a lactate.

[0013] [6] The cleaning composition according to [5], wherein the blending mass ratio of the lactic acid to the lactate, expressed as lactic acid / lactate, is 0.5 to 2.0.

[0014] [7] The cleaning agent composition according to any one of [1] to [6], which is a toilet cleaning agent.

[0015] [8] The cleaning composition according to any one of [1] to [7], further comprising a liquefied gas or a compressed gas.

[0016] [9] An aerosol cleaning product comprising a container equipped with an aerosol valve and filled with the cleaning agent composition described in [8]. Effect of the Invention

[0017] The present invention makes it possible to provide a cleaning agent composition that is excellent in all of the disinfecting effect, virus inactivation effect, and urinary stone removal effect, and to provide a cleaning aerosol product containing the same. [Brief description of the drawings]

[0018] [Figure 1] FIG. 1 is a schematic diagram showing the appearance of a cleaning aerosol product according to one embodiment of the present invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0019] Hereinafter, an embodiment of the present invention will be described. The cleaning agent composition according to an embodiment of the present invention (hereinafter referred to as "the cleaning agent composition") contains a silver complex, lactic acid, and a surfactant. The combined use of the silver complex and lactic acid exhibits excellent disinfecting effects, virus inactivation effects, and urinary stone removal effects.

[0020] <Silver complex> The present cleaning composition exhibits excellent disinfecting and virus inactivating effects by containing a silver complex. Examples of silver complexes include complexes of silver and amino acids (histidine, arginine, creatinine, etc.), complexes of silver and carboxylic acids (pyruvic acid, glycolic acid, acetic acid, butyric acid, salicylic acid, etc.), complexes of silver, carboxylic acids, and amino acids, and complexes of silver and imidazole derivatives (imidazoline, etc.), and it is preferable to use one or more of these. Among them, silver complexed with at least one selected from amino acids and carboxylic acids is preferable, and a complex of silver, carboxylic acid, and creatinine is particularly preferable.

[0021] The disinfecting effect and virus inactivation effect exhibited by the silver complex contained in the present cleaning composition are sufficiently exhibited even at a low concentration of the silver complex by using it in combination with lactic acid described later. Therefore, the lower limit of the blending ratio of the silver complex in the present cleaning composition may be, for example, 0.0001 mass% or more based on the total mass of the cleaning composition, and more preferably 0.001 mass% or more. The upper limit of the blending ratio of the silver complex in the present cleaning composition may be, for example, 5 mass% or less. Here, the silver concentration in the silver complex is, for example, preferably 0.1 mass% or more and 10 mass% or less based on the total mass of the silver complex. When the present cleaning composition contains two or more types of silver complexes, the above blending ratio of the silver complexes means the total blending ratio.

[0022] <Lactic acid> The cleaning composition contains lactic acid, which exhibits an excellent urinary stone removal effect, and as described above, due to the synergistic effect with the silver complex, exhibits an excellent disinfecting effect and virus inactivation effect even when the silver complex is used at a low concentration. This excellent synergistic effect with the silver complex cannot be obtained by using hydroxycarboxylic acids other than lactic acid, such as glycolic acid. The lactic acid may be fermented lactic acid or synthetic lactic acid.

[0023] The blending ratio of lactic acid in the present detergent composition is not particularly limited, but is preferably 0.1 to 5 mass %, more preferably 0.5 to 3 mass %, based on the total mass of the detergent composition.

[0024] <Surfactant> The detergent composition of the present invention exhibits excellent cleaning effects by containing a surfactant. The surfactant that the detergent composition of the present invention may contain is not particularly limited, and may be appropriately selected from nonionic surfactants, anionic surfactants, amphoteric surfactants, silicone surfactants, natural surfactants, amino acid surfactants, and the like. When the detergent composition is provided as an aerosol product described below, the surfactant may be appropriately selected from the viewpoint of foam forming properties.

[0025] Examples of nonionic surfactants include polyoxyethylene alkyl ethers such as polyoxyethylene (hereinafter referred to as "POE") cetyl ether, POE stearyl ether, POE oleyl ether, POE lauryl ether, POE behenyl ether, POE octyldodecyl ether, POE isocetyl ether, and POE isostearyl ether; polyoxyethylene sorbitan fatty acid esters such as POE sorbitan monococonut oil fatty acid, POE sorbitan monostearate, and POE sorbitan monooleate; polyoxyethylene polyoxypropylene alkyl ethers such as POE·POP cetyl ether and POE·POP decyltetradecyl ether; polyoxyethylene glycerin fatty acid esters such as POE glyceryl monostearate; polyoxyethylene lanolin alcohols such as POE lanolin alcohol; polyoxyethylene hydrogenated castor oils such as POE hydrogenated castor oil; and polyethylene glycols such as polyethylene glycol monostearate. polyglycerin fatty acid esters such as hexaglyceryl monolaurate, hexaglyceryl monomyristate, pentaglyceryl monolaurate, pentaglyceryl monomyristate, pentaglyceryl monooleate, pentaglyceryl monostearate, decaglyceryl monolaurate, decaglyceryl monomyristate, decaglyceryl monostearate, decaglyceryl monoisostearate, decaglyceryl monooleate, and decaglyceryl monolinoleate; polyoxyethylene glycerin fatty acid esters such as POE glyceryl monooleate; polyoxyethylene sorbitan fatty acid esters such as POE sorbitan monopalmitate, POE sorbitan monostearate, POE sorbitan monoisostearate, and POE sorbitan monooleate; polyoxyethylene sorbitan fatty acid esters such as POE sorbitan monolaurate, POE sorbitan tetrastearate, and POE sorbitan tetraoleate; and the like.

[0026] Examples of anionic surfactants include fatty acid salts such as sodium laurate, sodium palmitate, and coconut potassium soap; alkyl ether carboxylates such as POE lauryl ether carboxylate and POP·POE ether myristate; higher alkyl sulfates such as sodium lauryl sulfate, potassium lauryl sulfate, and triethanolamine lauryl sulfate; alkyl ether sulfates such as triethanolamine POE lauryl sulfate and sodium POE lauryl sulfate; N-acylamine salts such as sodium lauroyl sarcosine, sodium lauroyl-N-methyl-β-alanine, monosodium N-lauroyl glutamate, disodium N-stearoyl glutamate, monosodium N-myristoyl-L-glutamate, and diethanolamine N-palmitoyl aspartate; higher fatty acid amide sulfonates such as sodium N-myristoyl-N-methyl taurine, sodium coconut fatty acid methyl taurine, sodium lauroyl methyl taurine, and sodium POE lauryl amide ether sulfonate; sodium POE oleyl ether phosphate, P Phosphate salts such as OE stearyl ether phosphate and sodium POE lauryl amide ether phosphate; sulfosuccinates such as sodium di-2-ethylhexyl sulfosuccinate, sodium monolauroyl monoethanolamide polyoxyethylene sulfosuccinate, and sodium lauryl polypropylene glycol sulfosuccinate; alkylbenzene sulfonates such as sodium linear dodecylbenzene sulfonate, triethanolamine linear dodecylbenzene sulfonate, and linear dodecylbenzene sulfonic acid; higher fatty acid ester sulfate salts such as hydrogenated coconut oil fatty acid glycerin sulfate sodium, turpentine oil, and other sulfated oils, α-olefin sulfonates, higher fatty acid ester sulfonates, and secondary alcohol sulfate salts; higher fatty acid alkylolamide sulfate salts such as sodium lauroyl monoethanolamide succinate and sodium caseinate; sulfate salts or sulfonate salts of alkyl sulfate salts, polyoxyethylene alkyl sulfate salts, fatty acid amide ether sulfate salts, acyl isethionates, and sulfosuccinate salts;Examples of the surfactant include carboxylic acid type surfactants such as ether carboxylates, fatty acid amide ether carboxylates, N-acyliminodiacetic acid, and N-acylamino acid salts.

[0027] Examples of the salt form of the anionic surfactant include alkali metal salts such as sodium and potassium salts; Alkaline earth metal salts such as magnesium; monoethanolamine salts, diethanolamine salts and the like alkanolamine salts.

[0028] Examples of amphoteric surfactants include amine oxides such as alkyldimethylamine oxide, sulfobetaines such as alkyldimesylsulfobetaine, and carbobetaines.

[0029] Other examples of surfactants include silicone surfactants such as polyoxyethylene-methylpolysiloxane copolymer, polyoxypropylene-methylpolysiloxane copolymer, and poly(oxyethylene-oxypropylene)-methylpolysiloxane copolymer; natural surfactants such as sodium surfactin, cyclodextrin, and hydrogenated enzyme soy lecithin; and N-coconut oil fatty acid acyl-L-glutamic acid triethanolamine, N-coconut oil fatty acid acyl-L-glutamic acid potassium, N-coconut oil fatty acid acyl-L-glutamic acid sodium, N-lauroyl-L-glutamic acid triethanolamine, and N-lauroyl-L-glutamic acid potassium. and amino acid surfactants such as N-acyl glutamates, such as sodium N-lauroyl-L-glutamate, potassium N-myristoyl-L-glutamate, sodium N-myristoyl-L-glutamate, and sodium N-stearoyl-L-glutamate; N-acyl glutamic acids, such as N-coconut oil fatty acid acyl-L-glutamic acid, N-lauroyl-L-glutamic acid, and N-stearoyl-L-glutamic acid; N-acyl glycine salts, such as potassium N-coconut oil fatty acid acyl glycine and sodium N-coconut oil fatty acid acyl glycine; and N-acylalanine salts, such as N-coconut oil fatty acid acyl-DL-alanine triethanolamine.

[0030] These surfactants can be used alone or in combination of two or more. From the viewpoint of cleaning properties and stability of the silver complex, one or more selected from polyoxyethylene alkyl ether, sorbitan fatty acid ester, and polyoxyethylene alkyl ether sulfate are preferred, and it is particularly preferred to use either or both of polyoxyethylene alkyl ether and polyoxyethylene alkyl ether sulfate.

[0031] The blending ratio of the surfactant in the present cleaning composition is not particularly limited, but is preferably 0.1 to 10 mass %, more preferably 0.5 to 5 mass %, based on the total mass of the cleaning composition. When the present cleaning composition contains two or more surfactants, the blending ratio mentioned above means the blending ratio of the total.

[0032] <Lactate> The detergent composition further contains a lactate, which creates an equilibrium state between lactic acid molecules and lactate ions, thereby exhibiting the above-mentioned urinary stone removal, sterilization, and virus inactivation effects, and improving storage stability. In addition, when the detergent composition is used in the form of an aerosol product described below, it has an effect of suppressing corrosion of pressure-resistant containers. Examples of lactate include alkali metal salts such as sodium salts, potassium salts, and calcium salts.

[0033] The blending ratio of the lactate in the present detergent composition is not particularly limited, but is preferably 0.1 to 5 mass %, more preferably 0.5 to 3 mass %, based on the total mass of the detergent composition.

[0034] The blending mass ratio, expressed as lactic acid / lactate, is preferably 0.5 to 2.0, more preferably 0.6 to 1.5, and even more preferably 0.7 to 1.0.

[0035] <Optional ingredients> The toilet cleansing agent composition according to this embodiment may contain other optional components, such as a water-soluble solvent, a thickener, a pH adjuster, water, a fragrance, etc., within a range that does not impair the above-mentioned effects.

[0036] The water-soluble solvent that may be contained in the cleaning composition is not particularly limited. When the cleaning composition is provided as an aerosol product described later, it is preferable that the foam formability (foamability) can be adjusted. Specific examples of the water-soluble solvent include monohydric alcohols having 2 or 3 carbon atoms such as ethanol and isopropanol, and dihydric to trihydric polyols such as ethylene glycol, propylene glycol, 1,3-butylene glycol, hexylene glycol, diethylene glycol, dipropylene glycol, and glycerin. These can be used alone or in combination of two or more kinds, but it is preferable to use ethanol from the viewpoint of ease of adjusting the foam formability.

[0037] When the present cleaning composition contains a water-soluble solvent, the blending ratio of the water-soluble solvent is not particularly limited, but may be, for example, 1 to 20 mass % or 5 to 15 mass % based on the total mass of the composition.

[0038] The thickener that may be contained in the present cleaning composition is not particularly limited. When the composition is provided as an aerosol product described later, it is preferable that the thickener is capable of adjusting the persistence (retention) of the foam. Specific examples of the thickener include gums such as xanthan gum, carrageenan, gum arabic, gum tragacanth, cationized guar gum, guar gum, gellan gum, and locust bean gum; cellulose polymers such as hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, sodium carboxymethyl cellulose, nitrocellulose, and crystalline cellulose; dextran, sodium carboxymethyl dextran, dextrin, pectin, starch, corn starch, wheat starch, sodium alginate, modified potato starch, sodium hyaluronate, polyvinyl alcohol, polyvinylpyrrolidone, and carboxyvinyl polymers. These may be used alone or in combination of two or more kinds, but it is preferable to use hydroxyethyl cellulose from the viewpoint of excellent foam retention.

[0039] When the present cleaning composition contains a thickener, the blending ratio of the thickener is not particularly limited, but may be, for example, 0.01 to 5 mass %, or 0.1 to 1 mass %, based on the total mass of the composition.

[0040] The pH adjuster that may be contained in the present cleaning composition is not particularly limited. Specific examples of the pH adjuster include basic substances such as sodium hydroxide, potassium hydroxide, amines, ammonium salts, and ammonia; inorganic acids such as sulfuric acid, nitric acid, hydrochloric acid, and phosphoric acid; organic acids such as 1-hydroxy-1,1-diphosphonic acid, polycarboxylic acids, aminopolycarboxylic acids, and amino acids; and metal salts thereof. These may be used alone or in combination of two or more.

[0041] When the present cleaning composition contains a pH adjuster, the blending ratio of the pH adjuster is not particularly limited, but may be, for example, 0.01 to 5 mass %, or 0.1 to 1 mass %, based on the total mass of the composition.

[0042] In one embodiment, the present cleaning composition contains water as a main component. When the present cleaning composition contains water, the blending ratio of water is not particularly limited, and may be, for example, 70 to 99 mass % or 80 to 95 mass % based on the total mass of the composition.

[0043] When the cleaning composition is filled in a container equipped with an aerosol valve and provided as an aerosol product, it may further contain a propellant. Here, the aerosol product refers to a product in which the contents are self-discharged in the form of mist or foam outside the container through the valve by the propellant, and examples of such products include an upright aerosol valve and an inverted aerosol valve. Hereinafter, a cleaning composition containing a propellant is also referred to as an "aerosol composition", and components other than the propellant contained in the aerosol composition are also referred to as "stock solution" or "aqueous stock solution" in contrast to the "propellant". By forming the cleaning composition into an aerosol product, it becomes possible to store and provide the cleaning composition in a light-shielded state, and the silver complex contained in the cleaning composition can be stored in a stable state.

[0044] FIG. 1 is a schematic diagram showing the appearance of a cleaning aerosol product according to this embodiment. The cleaning aerosol product 1 shown in FIG. 1 is an inverted aerosol product, and includes a pressure-resistant container 2, an inverted aerosol valve 3, and an ejection member 4. The pressure-resistant container 2 is made of metal such as aluminum, tinplate, or stainless steel. The aerosol product 1 can be manufactured by filling the aqueous concentrate into the pressure-resistant container 2, fixing the inverted aerosol valve 3, and then filling the propellant. The cleaning aerosol product is preferably structured with a spout for foaming the concentrate. When the inverted aerosol valve 3 is opened and the aerosol composition is ejected, the ejected contents become fine mist or foam due to the sudden expansion of the propellant.

[0045] The propellant used in the aerosol composition according to the present embodiment may be a liquefied gas or a compressed gas, and is not particularly limited as long as it is vaporized when sprayed to the outside, foaming the aqueous concentrate, and forming foam. Examples of such liquefied gas include liquefied petroleum gas, which is propane, normal butane, isobutane, and mixtures thereof, hydrofluoroolefins such as trans-1,3,3,3-tetrafluoroprop-1-ene (HFO-1234ze) and trans-2,3,3,3-tetrafluoroprop-1-ene (HFO-1234yf), dimethyl ether, and mixtures thereof. Normal pentane and isopentane may also be blended into the liquefied gas. Examples of compressed gas include nitrogen gas, carbon dioxide gas, nitrous oxide gas, and mixtures thereof.

[0046] The internal pressure (20°C) of the pressure-resistant container when the aqueous concentrate and propellant are filled under pressure is preferably 0.20 to 0.55 MPa, more preferably 0.30 to 0.45 MPa. This internal pressure is a value measured by the static method. If the internal pressure is lower than 0.2 MPa, foam formation is poor, and if it is higher than 0.55 MPa, it may be difficult to adhere to the target object, and the foam may scatter and be easily inhaled by the user.

[0047] The blending ratio of the propellant in the aerosol composition in this embodiment is not particularly limited, and may be, for example, 3 to 40% by mass, or 5 to 35% by mass. If the blending ratio of the propellant is less than 3% by mass, foaming may be difficult, and if it is more than 40% by mass, scattering increases, making it difficult for the propellant to adhere to the target and making it easier for the user to inhale.

[0048] The method of using the aerosol product according to the present embodiment described above is not particularly limited, but for example, an appropriate amount can be sprayed onto the surface of the toilet bowl, including the area near the rim on the inside of the bowl, and then left for several to several tens of minutes until the foam disappears, and then rinsed with water or the like.

[0049] In addition to the above components, the cleaning composition according to the present embodiment may be combined with other known additives, such as other bactericides / disinfectants, ultraviolet absorbers, ultraviolet dispersion agents, colorants, preservatives, antioxidants, chelating agents, medicines, fragrances, etc., depending on the intended use, application, etc. The blending ratio of the other components is not particularly limited, but is, for example, 0.01 to 1.0 mass% based on the total mass of the cleaning composition according to the present embodiment.

[0050] The cleaning composition according to this embodiment can be applied to surfaces of ceramics, plastics, metals, glass, etc. used in walls, floors, utensils, equipment, etc. of toilets, bathrooms, kitchens, washstands, etc. For example, the cleaning composition according to the embodiment of the present invention is suitable for use on toilets, bathtubs, washstands, etc., which are prone to adhesion and accumulation of urinary stones, microorganisms, or viruses. EXAMPLES

[0051] Hereinafter, an embodiment of the present invention will be described using an example. ≪Raw materials≫ The raw materials used in the examples and comparative examples are as follows. <Silver complex> Complex of silver, carboxylic acid and creatinine (product name: AG Alpha CF-01, manufactured by J Chemical Co., Ltd., silver concentration 2.5% by mass) <Lactic acid> Fermented lactic acid (product name: PURAC HiPure90, manufactured by Corbion, active ingredient concentration 90% by mass) <Surfactant> Polyoxyethylene (9) alkyl (C12-14) ether (product name: Marpon ACF-9, manufactured by Matsumoto Oil Co., Ltd.) Sodium polyoxyethylene (2) lauryl ether sulfate (product name: genapol LRO liquid, Clariant, active ingredient concentration 30%) <Lactate> Sodium lactate (product name: PURASAL S / HQ60, manufactured by Corbion, active ingredient concentration 60% by weight)

[0052] <Other ingredients> Hydroxyethylcellulose Sodium hydroxide ·Fragrance 95% ethanol Ion-exchanged water

[0053] Table 1 shows the composition of each cleaning composition (ingredients and their contents (mass%)). The "balance" indicating the content of ion-exchanged water means the content added so that the total amount (mass%) of all ingredients contained in the cleaning composition becomes 100 mass%. The content of each ingredient means the content as an active ingredient, not the content as a product.

[0054] <Production Example of Detergent Composition> (Example 1, Comparative Example 1 and Comparative Example 2) Each of the cleaning compositions of Example 1, Comparative Example 1 and Comparative Example 2 was produced by uniformly mixing the components according to the formulation shown in Table 1 below. The disinfecting effect and urinary stone removal effect of each detergent composition were evaluated according to the following evaluation methods. The detergent composition of Example 1 was also evaluated for its virus inactivation effect.

[0055] <How to evaluate the sterilization effect> (a) Preparation of test bacteria solution Methylobacterium sp. was used as the test bacterium. The test bacterium was cultured in R2A liquid medium at 25°C for 7 days until the bacterial concentration reached approximately 10 5 ~10 6 The concentration was adjusted to CFU / mL to prepare a test bacterial solution.

[0056] (b) Inoculation of test bacteria solution 9 mL of each of the detergent compositions shown in Table 1 was placed in a test tube, and 1 mL of the test bacteria liquid prepared in (a) above was inoculated into the test tube to obtain a mixture of the detergent composition / bacteria liquid. This was allowed to stand for 10 minutes.

[0057] (c) Cultivation of test bacteria 100 μL of the mixture of the cleaning composition and the bacterial solution obtained in (b) above was cultured on R2A agar medium at 25° C. for 7 days. The colonies formed after the culture were counted and converted into the viable cell count. The obtained value was designated as Y.

[0058] As a control, the same test was performed using physiological saline instead of the above-mentioned cleaning composition, and the colonies formed after the culture were counted in the same manner, and the number of live bacteria was converted. The obtained value was designated as X. The disinfecting activity value was quantified using the following calculation formula, and was used as an index of antibacterial performance according to the following criteria. The evaluation results are shown in Table 1.

[0059] <Calculation formula for disinfection activity value> Sterilization activity value = logX-logY <Evaluation criteria> A: The disinfection activity value is 2 or more and the number of colonies is below the detection limit. B: Sterilization activity value is 2 or more C: Sterilization activity value is less than 2

[0060] <Method for evaluating the effectiveness of urinary stone removal> (a) Preparation of urinary stone model stain A transparent PP (polypropylene) plate was immersed in a liquid prepared by dispersing 0.1 g of cow's milk casein, 0.5 g of tricalcium phosphate, 0.2 g of urea, and 0.1 g of uric acid in 25 g of ethanol and 25 g of water, and then air-dried at room temperature for 3 hours to create a model urinary stone stain.

[0061] (b) Conducting cleaning tests A urinary stone model stain was immersed in each of the cleaning compositions prepared according to Table 1 for 10 minutes, and then rinsed in stored water for 1 second. The light transmittance at a wavelength of 600 nm was measured using a spectrophotometer for (i) the transparent PP plate before the urinary stone model stain was attached, (ii) the urinary stone model stain before cleaning, and (iii) the urinary stone model stain after cleaning, and the cleaning rate was quantified using the following formula and used as an index of urinary stone removal performance according to the following criteria. The evaluation results are shown in Table 1. <Cleaning rate calculation formula> Cleaning rate (%) = [(transmittance of iii - transmittance of ii) / (transmittance of i - transmittance of ii)] x 100

[0062] <Evaluation criteria> A: The cleaning rate is 50% or more. B: The cleaning rate is 25% or more but less than 50%. C: The cleaning rate is less than 25%.

[0063] [Table 1]

[0064] From Table 1, it can be seen that Example 1 has excellent disinfecting effect and urinary stone removing effect. In particular, it was found that the disinfecting effect of the composition was improved compared to the case where only the silver complex was used due to the synergistic effect of the combined use of the silver complex and lactic acid.

[0065] <How to evaluate virus inactivation effect> Using influenza A virus (H3N2), the cleaning composition of Example 1 was subjected to an evaluation test of its virus inactivation effect. An influenza virus suspension and the cleaning composition of Example 1 were mixed at a ratio of 9:1, and the mixture was left at room temperature for 5 minutes, after which the reaction was stopped. This sample was mixed with a cell growth medium and cultured, and the virus infectivity (pfu / ml, common logarithm) per 1 ml of the test liquid was calculated by the plaque measurement method. As a control, a similar test was performed using PBS (phosphate buffered saline) instead of the cleaning composition of Example 1, and the virus infectivity was 6.92 for the control and less than 2.0 for the cleaning composition of Example 1. From these results, it was confirmed that the cleaning composition of Example 1 has a virus inactivation effect that reduces the virus infectivity by 4.9 or more. In this evaluation method, if the reduction in virus infectivity is 2 or more, it is judged that the cleaning agent has practical use as a cleaning agent having a virus inactivation effect. Therefore, it can be seen that the composition of Example 1 has an excellent virus inactivation effect.

[0066] <Production and evaluation of cleaning aerosol products> The cleaning composition of Example 1 was used as an aqueous concentrate. 243 g (90%) of this aqueous concentrate was filled into an aluminum pressure-resistant container 2 constituting an aerosol product 1 as shown in Fig. 1. After an inverted aerosol valve 3 was fixed to this pressure-resistant container 2, 27 g (10%) of LPG having a vapor pressure of 0.4 MPa at 20°C was filled as a propellant. Further, an injection member 4 was attached, and an aerosol product 1 having the appearance shown in Fig. 1 was produced.

[0067] The above aerosol product was sprayed upside down for about 5 seconds around the rim of a household ceramic toilet. After leaving it for about 10 minutes until the foam from the sprayed cleaning agent had spread to the center of the toilet bowl, the bowl was then washed with water, and it was confirmed that the product had a sufficient cleaning effect on urinary stone stains.

[0068] The present invention is not limited to the above-mentioned embodiment, and can be modified in various ways without departing from the gist of the present invention. The embodiments may be combined as appropriate, and in that case, the combined effect can be obtained. Furthermore, the above-mentioned embodiment includes various inventions, and various inventions can be extracted by combinations selected from the multiple components disclosed. For example, if the problem can be solved and the effect can be obtained even if some components are deleted from all the components shown in the embodiment, the configuration from which the components are deleted can be extracted as an invention. [Explanation of symbols]

[0069] 1. Aerosol products 2. Pressure vessel 3 Inverted aerosol valve 4 Injection member

Claims

1. A cleaning composition for removing urinary stones, comprising a silver complex, lactic acid, and a surfactant.

2. A cleaning composition for removing urinary stones, comprising a silver complex, lactic acid, and a nonionic surfactant as a surfactant.

3. The cleaning agent composition for removing urinary stones according to claim 1 or 2, comprising, as the silver complex, one or more complexes selected from the group consisting of a complex of silver and an amino acid, a complex of silver and a carboxylic acid, a complex of silver, a carboxylic acid and an amino acid, and a complex of silver and an imidazole derivative.

4. The cleaning composition for removing urinary stones according to any one of claims 1 to 3, comprising as the silver complex at least a complex of silver, a carboxylic acid and creatinine.

5. The cleaning composition for removing urinary stones according to any one of claims 1 to 4, comprising, as the surfactant, a polyoxyethylene alkyl ether and / or a polyoxyethylene alkyl ether sulfate.

6. The cleaning composition for removing urinary stones according to any one of claims 1 to 5, further comprising a lactate salt.

7. The cleaning composition for removing urinary stones according to claim 6, wherein a blending mass ratio of said lactic acid to said lactate, expressed as lactic acid / lactate, is 0.5 to 2.

0.

8. The cleaning composition for removing urinary stones according to any one of claims 1 to 7, which is a toilet cleaning agent.

9. The cleaning composition for removing urinary stones according to any one of claims 1 to 8, further comprising a liquefied gas or a compressed gas.

10. 10. An aerosol cleaning product comprising a container equipped with an aerosol valve and filled with the cleaning agent composition for removing urinary stones according to claim 9.

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