A device that activates mitochondria

Abstract

A method for activating mitochondria is provided. [Solution] The present invention is a method for activating mitochondria by supplying mitochondria with negative charges and reactive oxygen species from the outside via a negative charge and reactive oxygen supply unit, which serves as the raw material for mitochondrial redox. The calcium ion channel facilitating unit allows calcium ions from the body to enter the mitochondrial matrix space via calcium transport proteins on the inner mitochondrial membrane. The influx of calcium ions promotes mitochondrial depolarization and improves mitochondrial oxidative phosphorylation activity, thereby promoting mitochondrial activation and ATP production.

Description

[Technical Field]

[0001] The present invention activates mitochondria Device In particular, the present invention relates to a method for supplying negative charges and active oxygen to mitochondria from outside the body via a negative charge and active oxygen supply unit, and then allowing calcium ions from within the body to enter the mitochondrial matrix space via a calcium ion channel promoting unit via a calcium transport protein on the inner mitochondrial membrane, thereby promoting mitochondrial activation and ATP production. [Background technology]

[0002] According to this study, mitochondria are the energy-producing units within cells and the energy factories of cells. Each mitochondrion is composed of an outer membrane and an inner membrane, and the space surrounded by the inner membrane is called the matrix space. Enzymes related to biooxidation reactions are embedded in the outer membrane of mitochondria, providing the raw materials for internal mitochondrial reactions. The matrix space within mitochondria contains enzymes that metabolize carbohydrate, protein, and fat products into H2O and CO2 through the citric acid cycle. During this process, electrons move through the respiratory enzyme chain and oxidative phosphorylation is used to synthesize the high-energy phosphate compound adenosine triphosphate (ATP). ATP is the primary energy source for energy-consuming reactions in plants and animals. ATP is a biochemical nucleotide that serves as the "energy currency" for intracellular energy transfer, storage, and transfer of chemical energy. ATP also plays an important role in nucleic acid synthesis. It is also the guanine dinucleotide in RNA sequences and can be used as a substitute for DNA transcription.

[0003] However, for mitochondria to generate energy, continuous oxidation-reduction reactions are required. The sources of oxidation-reduction reactions depend on negative charges (-e) and reactive oxygen species (O), which act as the raw materials for mitochondria to function. Providing these raw materials will allow mitochondria to function more effectively. Furthermore, calcium ion influx plays an important role in mitochondrial activation and ATP production.

[0004] 1. Regulation of calcium ions in mitochondria: Calcium can enter mitochondria and affect their function. When calcium concentration in the cytoplasm increases, calcium ions pass through the calcium ions on the inner mitochondrial membrane and transport proteins into the mitochondrial matrix space. This influx of calcium ions promotes mitochondrial depolarization, thereby increasing mitochondrial oxidative phosphorylation activity.

[0005] 2. Promotes oxidative phosphorylation: Increased calcium ions can activate various mitochondrial enzyme systems, including key enzymes in the tricarboxylic acid cycle (TCA). Activation of these enzymes allows mitochondria to accelerate substrate oxidation, improve the efficiency of the electron transport chain, and ultimately increase ATP production.

[0006] 3.Increased ATP synthesis: Increasing calcium concentration in mitochondria increases the rates of the tricarboxylic acid cycle (TCA cycle) and oxidative phosphorylation. Oxidative phosphorylation, a cellular metabolic pathway occurring in the inner mitochondrial membrane of eukaryotes or the plasma membrane of prokaryotes, synthesizes adenosine triphosphate (ATP) using the energy released by the oxidation of various nutrients with enzymes within it, directly increasing ATP production. ATP production is driven by the action of the electron transport chain, and these processes, facilitated by calcium ions, ensure the continuity and efficiency of ATP production.

[0007] 4. Maintains cellular energy balance: Increased ATP production helps cells maintain energy balance, especially in response to various stresses, which also aids in cellular repair and normalization to avoid cell death due to energy deficiency.

[0008] Therefore, when the negative charge (-e) and reactive oxygen (O) necessary for mitochondrial oxidation-reduction are continuously provided from the outside and calcium ions in the body are promoted to enter the mitochondrial matrix space via calcium transport proteins in the inner mitochondrial membrane, mitochondrial activation and ATP production are promoted. Summary of the Invention [Problem to be solved by the invention]

[0009] The main objective of the present invention is to develop a method for activating mitochondria that can enhance mitochondrial activation and ATP production. Device The purpose is to provide [Means for solving the problem]

[0010] The main features of the present invention are as follows: Negative charge and reactive oxygen species are supplied to mitochondria from the outside as raw materials for mitochondrial redox via the negative charge and reactive oxygen species supplying unit. . Calcium ions in the body enter the mitochondrial matrix space via calcium transport proteins on the inner mitochondrial membrane via the calcium ion channel facilitating unit, and the influx of calcium ions promotes mitochondrial depolarization and increases mitochondrial oxidative phosphorylation activity, thereby promoting mitochondrial activation and ATP production.

[0011] The following embodiments will be described as technical means used in the present invention to achieve the above objects and effects. [Effects of the Invention]

[0012] 1. It can regulate calcium ions in mitochondria. 2. Promotes oxidative phosphorylation. 3. ATP synthesis increases. 4. Maintaining cellular energy balance. [Brief explanation of the drawings]

[0013] [Figure 1] FIG. 1 is a block diagram of a preferred embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0014] See Figure 1. Activating mitochondria according to a preferred embodiment of the present invention Device is as follows:

[0015] Supplying mitochondria with negative charges (-e) and reactive oxygen species (O) . The negative charge and active oxygen are supplied to mitochondria from the outside through the negative charge and active oxygen supply unit 1, and become raw materials for mitochondrial redox. The negative charge and active oxygen supply unit 1 can be achieved by energizing a low-temperature plasma generator. When the low-temperature plasma generation unit is energized, a large amount of negative charge (-e) and active oxygen (O) is generated, and a large amount of negative charge (-e) and active oxygen (O) enters the body as raw materials for mitochondrial redox.

[0016] Supplies calcium ions to mitochondria. Through the calcium ion channel promoting unit 2, calcium ions in the body are promoted to enter the mitochondrial matrix space via the calcium transport protein on the mitochondrial inner membrane, and the influx of calcium ions promotes mitochondrial depolarization. The calcium ion channel promoting unit 2 can be a far-infrared generator with a power of 500 watts or more, and the body is irradiated with infrared light through the far-infrared generator to promote the calcium ions in the body to enter the mitochondrial matrix space via the calcium transport protein on the mitochondrial inner membrane.

[0017] Through negative charge and active oxygen supply unit 1 This provides mitochondria with sufficient negative charge (-e) and reactive oxygen (O) sources. Next, in step 2, calcium ions in the body are promoted to enter the mitochondrial matrix space by calcium transport proteins on the mitochondrial inner membrane via calcium ion channel promoting unit 2. The influx of calcium ions promotes mitochondrial depolarization, activating mitochondria and promoting ATP production.

[0018] Next, the present invention conducted a test through Taiwan Mitochondrial Application Technology Corporation to test the mitochondrial activation of peripheral blood mononuclear cells of test subjects A, B, and C before use of the present invention, one hour after the second use, and one hour after the fourth use. The test results are shown in Table 1 for the first, second, and third measurement times, respectively. As shown in Table 1, mitochondria were clearly activated in all subjects after use of the present invention, demonstrating that the present invention is clearly effective and has industrial applicability. [Table 1]

[0019] Although the present invention has been described above with reference to the embodiments, the present invention is not limited to the above embodiments and can be implemented in various modifications without departing from the spirit of the present invention. Therefore, the scope of the present invention is defined by the appended claims. [Explanation of symbols]

[0020] 1. Negative charge and active oxygen supply unit 2. Calcium Ion Channel Facilitation Unit

Claims

1. A device for activating mitochondria, comprising: One negative charge and reactive oxygen are supplied to mitochondria from the outside through the negative charge and reactive oxygen supply unit, and become the raw material for mitochondrial redox. A device for activating mitochondria, characterized in that it supplies one calcium ion, and through a calcium ion channel promoting unit, calcium ions in the body are promoted to enter the mitochondrial matrix space via calcium transport proteins on the mitochondrial inner membrane, and the influx of calcium ions promotes mitochondrial depolarization and improves mitochondrial oxidative phosphorylation activity.

2. 2. The apparatus for activating mitochondria according to claim 1, wherein the negative charge and active oxygen supply unit is a low-temperature plasma generator.

3. 3. The device for activating mitochondria according to claim 1, wherein the calcium ion channel promoting unit is a far-infrared ray generator having a power of 500 watts or more.

Images