Particle beam irradiation system and particle beam irradiation method

The system addresses inefficiencies in particle beam therapy by allowing independent operation of multiple generators and shared transport, ensuring continuous irradiation across multiple rooms even with generator failures, thus enhancing treatment efficiency.

JP7817965B2Active Publication Date: 2026-02-19HITACHI LTD
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Patent Information

Application Number
JP2023045073
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Filing Date
2023-03-22
Publication Date
2026-02-19
Estimated Expiration
2043-03-22

AI Technical Summary

Technical Problem

Existing particle beam therapy systems face inefficiencies due to the inability to operate multiple accelerators independently, leading to reduced throughput when one fails, and the need for simultaneous irradiation in multiple rooms.

Method used

A particle beam irradiation system with two or more independently operable charged particle beam generators and a shared beam transport system that allows simultaneous beam transport to multiple irradiation devices, ensuring continued operation even if one generator fails.

Benefits of technology

Enables simultaneous irradiation across multiple devices, minimizing throughput loss during generator failures and increasing patient treatment capacity.

✦ Generated by Eureka AI based on patent content.

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Abstract

To enable simultaneous irradiation in a plurality of irradiation chambers and to minimize the lowering of throughput at the time of a failure of an accelerator.SOLUTION: A particle beam irradiation system 100 according to one aspect of the present invention includes: two or more charged particle beam generation devices 1 that can be independently operated; a beam transport system 2 that transports charged particle beams generated by the charged particle beam generation devices 1; and two or more beam irradiation devices 3 to which the charged particle beams are transported by the beam transport system 2. Any one of the beam irradiation devices 3 is configured to be capable of beam transportation from the plurality of charged particle beam generation devices 1, and the charged particle beams are simultaneously transported from each of the plurality of charged particle beam generation devices 1 to each of the corresponding different beam irradiation devices 3.SELECTED DRAWING: Figure 2
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Description

[Technical Field]

[0001] The present invention relates to a particle beam irradiation system and a particle beam irradiation method. [Background technology]

[0002] In particle beam therapy, the patient must be positioned before irradiation so that the particle beam can be irradiated at the planned location. After positioning is complete, the patient must remain in the same position and cannot move until the beam irradiation is complete. In addition, particle beams cannot be transported from one accelerator to multiple irradiation rooms (beam irradiation devices) simultaneously. Therefore, if the accelerator being used is currently transporting particle beams to another irradiation room when positioning is complete, a waiting time will occur until the beam irradiation to that irradiation room is completed, which reduces efficiency and places a burden on the patient. Therefore, methods have been devised to irradiate beams simultaneously in multiple irradiation rooms.

[0003] For example, Patent Document 1 discloses an accelerator system that accelerates an ion beam in a post-accelerator consisting of a synchrotron and supplies high-energy ion beams to multiple irradiation chambers for treatment. In this accelerator system, one post-accelerator and multiple treatment chambers (irradiation systems) are connected via a transportation system. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Japanese Patent Application Laid-Open No. 2005-302734 Summary of the Invention [Problem to be solved by the invention]

[0005] As disclosed in Patent Document 1, a method has already been invented that enables simultaneous beam irradiation in multiple irradiation chambers. However, due to reasons such as the inability to operate multiple accelerators independently and the fact that each irradiation chamber is assigned a specific accelerator to transport the particle beam, if one accelerator fails, one or more irradiation chambers will become unusable. In other words, since the configuration always involves irradiation chambers that cannot be used if an accelerator fails, throughput will be significantly reduced when an accelerator fails.

[0006] Given the above situation, there was a demand for a method that would enable simultaneous irradiation in multiple irradiation chambers and minimize the decrease in throughput in the event of an accelerator failure. [Means for solving the problem]

[0007] To achieve the above object, a particle beam irradiation system according to one aspect of the present invention includes two or more independently operable charged particle beam generators, a beam transport system for transporting the charged particle beams generated by the charged particle beam generators, and two or more beam irradiation devices to which the charged particle beams are transported by the beam transport system. The particle beam irradiation system is configured so that beam transport from a plurality of charged particle beam generators to any one of the beam irradiation devices is possible, and the charged particle beams are simultaneously transported from each of the plurality of charged particle beam generators to the corresponding different beam irradiation devices. [Effects of the Invention]

[0008] According to at least one aspect of the present invention, simultaneous irradiation by a plurality of beam irradiation devices is possible, and a decrease in throughput when a charged particle beam generator fails can be minimized. Problems, configurations, and effects other than those described above will become apparent from the following description of the embodiments. [Brief explanation of the drawings]

[0009] [Figure 1] 1 is a diagram showing an outline of a particle beam irradiation system according to an embodiment of the present invention; [Figure 2]FIG. 1 is a diagram illustrating an example of a minimum configuration of a particle beam irradiation system according to an embodiment of the present invention. [Figure 3] FIG. 10 is a diagram showing another example of the configuration of a particle beam irradiation system according to an embodiment of the present invention. [Figure 4] FIG. 2 is a diagram illustrating an example of a hardware configuration of an overall control device according to an embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0010] Hereinafter, examples of modes for carrying out the present invention (hereinafter referred to as "embodiments") will be described with reference to the accompanying drawings. In this specification and the accompanying drawings, identical components or components having substantially the same functions will be assigned the same reference numerals, and redundant explanations will be omitted. Furthermore, when there are multiple components having the same or similar functions, they may be described using the same reference numerals with different subscripts. Furthermore, when it is not necessary to distinguish between these multiple components, the subscripts may be omitted in the description.

[0011] First Embodiment [Outline of particle beam irradiation system] First, the general configuration of a particle beam irradiation system according to one embodiment of the present invention will be described with reference to FIG. Fig. 1 is a diagram showing an outline of a particle beam irradiation system according to this embodiment. As shown in Fig. 1, the particle beam irradiation system 100 according to this embodiment includes a charged particle beam generator 1, a beam transport system 2, and a beam irradiation device 3. Generally, a particle beam irradiation system includes a charged particle beam generator, a beam transport system, and a beam irradiation device.

[0012] The charged particle beam generator 1 has an ion source (not shown), a pre-accelerator 11, and a circular accelerator (synchrotron) 12, and generates a charged particle beam 32. In this embodiment, a synchrotron is used as the circular accelerator 12, but other accelerators such as a cyclotron may be used. An ion source is connected upstream of the pre-accelerator 11, and the circular accelerator 12 is connected downstream of the pre-accelerator 11. As shown in FIGS. 2 and 3 described below, a particle beam irradiation system 100 in this embodiment includes a plurality of charged particle beam generators 1.

[0013] The beam transport system 2 is connected downstream of the charged particle beam generator 1, and connects the charged particle beam generator 1 to the beam irradiation device 3 using a vacuum pipe 5. The vacuum pipe 5 is provided with multiple bending electromagnets 6. The charged particle beam 32 generated by the charged particle beam generator 1 passes through the beam transport system 2 and is guided by the bending electromagnets 6 to the beam irradiation device 3 in each irradiation chamber.

[0014] The bending electromagnets 6 are arranged as a pair of electromagnets facing each other across the vacuum pipe 5. A magnetic field is generated between the pair of electromagnets depending on the electrical energy applied to the bending electromagnets 6, and the direction of the charged particle beam passing between these electromagnets changes. The vacuum pipe 5 in the portion where the bending electromagnets 6 are arranged is formed in a structure that can accommodate both the charged particle beam traveling in a straight line and the charged particle beam bending in a vertical direction. Then, by controlling the strength of the magnetic field applied to the bending electromagnets 6, the charged particle beam can be made to travel in a straight line or bent in a vertical direction.

[0015] 2 and 3, which will be described later, the particle beam irradiation system 100 of this embodiment can be provided with a plurality of beam irradiation devices 3. When a plurality of beam irradiation devices 3 is provided, the charged particle beam 7 is guided to the beam irradiation device 3 by controlling the bending electromagnet 6 at an appropriate position among the plurality of bending electromagnets 6 provided in the beam transport line 2.

[0016] The beam irradiation device 3 is a device for irradiating the charged particle beam 7 transported by the beam transport line 2 onto the affected area of ​​a patient 42 waiting in a treatment room 4. As shown in Fig. 1, the beam irradiation device 3 of this embodiment includes a treatment table 41 on which the patient 42 is placed, an irradiation nozzle (nozzle device) 31, and a rotating gantry 30. Note that the beam irradiation device may be a fixed irradiation type (two-dimensional planar type) beam irradiation device that does not have a rotating gantry 30.

[0017] [Minimum configuration of particle beam irradiation system] Next, the minimum configuration of the particle beam irradiation system according to this embodiment will be described with reference to FIG. Fig. 2 is a diagram showing an example of the minimum configuration of the particle beam irradiation system 100. As shown in Fig. 2, the minimum configuration of the particle beam irradiation system includes two charged particle beam generators 1-1 and 1-2 and two beam irradiation devices 3-1 and 3-2. The beam irradiation devices 3-1 and 3-2 are installed in separate treatment rooms 4 (Fig. 1).

[0018] The charged particle beam generators 1-1 and 1-2 and the beam irradiation devices 3-1 and 3-2 have the same structures as the charged particle beam generator 1 and the beam irradiation device 3 shown in Figure 1, respectively. The charged particle beam generators 1-1 and 1-2 can be operated independently, and even if one of the charged particle beam generators 1-1 and 1-2 fails, the other charged particle beam generator can still operate. In other words, the two charged particle beam generators are physically separate and are controlled independently of each other. Furthermore, the types of ion sources used by the two charged particle beam generators 1-1 and 1-2 do not matter, and they may be the same or different nuclides.

[0019] In this embodiment, the beam irradiation device 3-1 or 3-2 is configured to be capable of receiving beams from the charged particle beam generators 1-1 or 1-2. However, beams from multiple charged particle beam generators are not simultaneously transported to one beam irradiation device.

[0020] 2, bending electromagnets 61-1, 61-2 and a bending electromagnet 62-1 are provided in the beam transport line 2. The bending electromagnets 61-1 to 61-2 and 62-1 each have the same structure as the bending electromagnet 6 in FIG.

[0021] In this particle beam irradiation system 100, the charged particle beam generated in the charged particle beam generator 1-1 can be transported to the beam irradiation device 3-1 via bending electromagnets 61-1 and 62-1 of the beam transport line 2. In addition, the charged particle beam generated in the charged particle beam generator 1-1 can be transported to the beam irradiation device 3-2 via bending electromagnets 61-1 and 61-2 of the beam transport line 2. In addition, the charged particle beam generated in the charged particle beam generator 1-2 can be transported to the beam irradiation device 3-1 via bending electromagnet 62-1 of the beam transport line 2.

[0022] The particle beam irradiation system 100 includes a general control device 21 that outputs control signals to the charged particle beam generators 1-1 and 1-2 and the bending electromagnets 61-1 to 61-2 and 62-1 to control the operations of the charged particle beam generators and the bending electromagnets.

[0023] A memory unit 22 that stores the relationship between energy and magnetic field is connected to the overall control device 21. The strength of the magnetic field determines the acceleration of the charged particles. Generally, for charged particles with the same charge, the stronger the magnetic field, the greater the energy that the charged particles receive from the magnetic field, and the greater the kinetic energy (acceleration) of the charged particles.

[0024] Furthermore, the overall control device 21 outputs commands to a control device (not shown) provided for the bending electromagnets. A control device for the bending electromagnets may be provided for each bending electromagnet, or one control device may be provided for each group consisting of multiple bending electromagnets (for example, a group determined in consideration of the transport path of the charged particle beam). Upon receiving a command from the overall control device 21, the control device for the bending electromagnets supplies electrical energy to the corresponding bending electromagnet to generate a magnetic field and switch the beam transport.

[0025] 2, the direction of travel of the charged particle beam generated by the charged particle beam generator 1-1 is changed to a vertical direction by the bending electromagnet 61-1, and then transported to the beam irradiation device 3-1 via the bending electromagnet 62-1. The charged particle beam generated by the charged particle beam generator 1-1 is then transported to the beam irradiation device 3-2 via the bending electromagnets 61-1 and 61-2. The charged particle beam generated by the charged particle beam generator 1-2 is then changed to a vertical direction by the bending electromagnet 62-1, and then transported to the beam irradiation device 3-1.

[0026] Furthermore, the particle beam irradiation system 100 is equipped with a control device (not shown) that controls the operation of the beam irradiation devices 3-1 and 3-2. This control device controls the operation of the beam irradiation devices 3-1 and 3-2 in response to an instruction from an engineer or based on preset conditions, thereby irradiating the charged particle beam to a target position of a patient 42 sitting on a treatment couch 41 in each treatment room 4.

[0027] In this way, in this embodiment, a first charged particle beam is transported from a first charged particle beam generator to a first beam irradiation device, and in parallel with this, a second charged particle beam is transported from a second charged particle beam generator to a second beam irradiation device using a shared beam transport system.

[0028] In this embodiment having the above configuration, the transport path of the charged particle beam is separated for each charged particle beam generator, so that charged particle beams can be irradiated in parallel in a plurality of beam irradiation devices (treatment rooms).

[0029] [Other configurations of particle beam irradiation systems] The number of charged particle beam generators, the number of beam irradiation devices, and their arrangement vary from facility to facility. Here, as a representative example, a particle beam irradiation system with two charged particle beam generators and three beam irradiation devices will be described with reference to Figure 3.

[0030] Fig. 3 is a diagram showing another example of the configuration of a particle beam irradiation system according to this embodiment. The particle beam irradiation system 100A shown in Fig. 3 includes, as a representative example, two charged particle beam generators 1-1 and 1-2 and three beam irradiation devices 3-1, 3-2, and 3-3. The beam irradiation devices 3-1 to 3-3 are installed in separate treatment rooms 4 (Fig. 1).

[0031] The charged particle beam generators 1-1 and 1-2 and the beam irradiation devices 3-1, 3-2, and 3-3 have the same structures as the charged particle beam generator 1 and the beam irradiation device 3 shown in Figure 1. As in Figure 2, the charged particle beam generators 1-1 and 1-2 can be operated independently, and even if one of the charged particle beam generators 1-1 and 1-2 fails, the other charged particle beam generator can still operate. Furthermore, the types of ion sources used by the two charged particle beam generators 1-1 and 1-2 do not matter, and they may use the same nuclide or different nuclides.

[0032] 3, bending electromagnets 61-1, 61-2, and 61-3, and bending electromagnets 62-1 and 62-1 are provided in the beam transport line 2. The bending electromagnets 61-1 to 61-3 and 62-1 to 62-2 each have the same structure as the bending electromagnet 6 in FIG. 1. Hereinafter, when it is not necessary to distinguish between these bending electromagnets, they will be referred to as bending electromagnet 61.

[0033] The particle beam irradiation system 100A is configured so that beams can be transported from multiple charged particle beam generators 1-1 and 1-2 to any one of the beam irradiation devices 3-1, 3-2, and 3-3. In the example of Fig. 3, a charged particle beam can be transported from the charged particle beam generator 1-1 to the beam irradiation devices 3-1, 3-2, and 3-3, and from the charged particle beam generator 1-2 to the beam irradiation devices 3-1 and 3-2. However, beams cannot be transported from multiple charged particle beam generators to one beam irradiation device at the same time.

[0034] For example, a charged particle beam generated by the charged particle beam generator 1-1 can be transported to the beam irradiation device 3-1 via the vacuum pipe 51-1, bending electromagnet 61-1, vacuum pipe 53-1, bending electromagnet 62-1, and vacuum pipe 53-2 of the beam transport system 2. Also, a charged particle beam generated by the charged particle beam generator 1-1 can be transported to the beam irradiation device 3-2 via the vacuum pipe 51-1, bending electromagnet 61-1, vacuum pipe 51-2, bending electromagnet 61-2, vacuum pipe 54-1, bending electromagnet 62-2, and vacuum pipe 54-2 of the beam transport system 2. Furthermore, the charged particle beam generated by the charged particle beam generator 1-1 can be transported to the beam irradiation device 3-3 via the vacuum pipe 51-1, bending electromagnet 61-1, vacuum pipe 51-2, bending electromagnet 61-2, vacuum pipe 51-3, bending electromagnet 61-3, and vacuum pipe 55 of the beam transport system 2.

[0035] The charged particle beam generated in the charged particle beam generator 1-2 can be transported to the beam irradiation device 3-1 via the vacuum pipe 52-1, bending electromagnet 62-1, and vacuum pipe 53-2 of the beam transport system 2. The charged particle beam generated in the charged particle beam generator 1-2 can be transported to the beam irradiation device 3-2 via the vacuum pipe 52-1, bending electromagnet 62-1, vacuum pipe 52-2, bending electromagnet 62-2, and vacuum pipe 54-2 of the beam transport system 2. The vacuum pipe 52-2 and vacuum pipe 55 may be connected.

[0036] As described above, the particle beam irradiation system according to this embodiment includes two or more independently operable charged particle beam generators, a beam transport system for transporting the charged particle beams generated by the charged particle beam generators, and two or more beam irradiation devices to which the charged particle beams are transported by the beam transport system. The particle beam irradiation system is configured so that beams can be transported from multiple charged particle beam generators to any one of the beam irradiation devices, and the charged particle beams are simultaneously transported from each of the multiple charged particle beam generators to the corresponding different beam irradiation devices.

[0037] According to this embodiment having the above configuration, the charged particle beam generator that can transport the beam to the beam irradiation device (treatment room) is not limited, and multiple charged particle beam generators can be operated independently, which enables simultaneous irradiation by multiple beam irradiation devices and increases the number of patients treated per hour. Furthermore, this embodiment can minimize the decrease in throughput when a charged particle beam generator fails.

[0038] In addition, in the above-mentioned particle beam irradiation system 100A, there may be a point (e.g., bending electromagnet 62-1) where the traveling direction of the first charged particle beam and the traveling direction of the second charged particle beam intersect within the vacuum piping at the location where the bending electromagnet is located in the shared beam transport system.

[0039] Here, in a portion where charged particle beams transported from two charged particle beam generators 1-1 and 1-2 may intersect, it does not matter whether the beam transport systems through which the intersecting charged particle beams pass are independent of each other. For example, when a charged particle beam is transported from the charged particle beam generator 1-1 to the beam irradiation device 3-1 and from the charged particle beam generator 1-2 to the beam irradiation device 3-2, the charged particle beams will intersect at the bending electromagnet 62-1, but the vacuum pipes 53-1 and 52-1 used may be independent or may be a common pipe. In other words, the vacuum pipes 53-1 and 52-1 may be independent of each other or may be connected to each other.

[0040] Furthermore, the vacuum pipes 52-1 and 53-2 used to transport the beam from the charged particle beam generator 1-2 to the beam irradiation device 3-1 may be independent or may be a common pipe.

[0041] Furthermore, even when a common beam transport system is used, beam transport from the charged particle beam generator 1-2 to the beam irradiation device 3-2 can be performed in parallel while beam transport from the charged particle beam generator 1-1 to the beam irradiation device 3-1 is in progress. When charged particle beams transported from the charged particle beam generators 1-1 and 1-2 simultaneously pass through a bending electromagnet 61 (e.g., bending electromagnet 62-1), there is no need to apply a magnetic field to the bending electromagnet 61 to bend the charged particle beams vertically. Therefore, at the bending electromagnet 61 where the two charged particle beams intersect, each of the two charged particle beams passes straight through. Furthermore, the probability of collision between the intersecting charged particle beams (the probability of particles being present at a certain location) is negligibly low. The most desirable state for two charged particle beams to intersect is orthogonal (perpendicular).

[0042] In this way, it is possible to simultaneously transport charged particle beams from two charged particle beam generators to a plurality of beam irradiation devices.

[0043] Furthermore, for example, if the charged particle beam generator 1-2 breaks down, the beam irradiation devices 3-1 and 3-2 can continue to be used as beam irradiation devices by using the charged particle beam generator 1-1 in the configuration of Figure 3. Therefore, the decrease in throughput when the charged particle beam generator 1-2 breaks down can be minimized.

[0044] [Hardware configuration of the overall control device] Next, the configuration (hardware configuration) of the control system of the overall control device 21 that constitutes the particle beam irradiation system 100 shown in FIGS. 1 and 2 will be described with reference to FIG.

[0045] Fig. 4 is a diagram showing an example of the hardware configuration of the overall control device 21. A calculator 70 shown in Fig. 4 is hardware used as a so-called computer.

[0046] The computer 200 includes a CPU (Central Processing Unit) 71, a ROM (Read Only Memory) 72, a RAM (Random Access Memory) 73, a non-volatile storage 74, and a communication interface 75, which are all connected to a bus.

[0047] The CPU 71 reads out program code of software that realizes each function according to this embodiment from the ROM 72, expands it in the RAM 73, and executes it. Alternatively, the CPU 71 may read out the program code directly from the ROM 72 and execute it as is. Note that the computer 70 may include a processing device such as an MPU (Micro-Processing Unit) instead of the CPU 71.

[0048] The RAM 73 temporarily stores variables, parameters, and the like that are generated during the calculation process by the CPU 71. If the RAM 73 is configured from a non-volatile medium, various types of information such as temporary communication path information may be stored in the RAM 73.

[0049] The beam transport switching function in the overall control device 21 is realized by the CPU 71 reading and executing a program for realizing this function from the ROM 72. For example, when the overall control device 21 receives a command from an engineer to switch between the charged particle beam generator and the beam irradiation device, it executes the beam transport switching based on the content of the command.

[0050] The nonvolatile storage 74 may be, for example, a hard disk drive (HDD), a solid state drive (SSD), a flexible disk, an optical disk, a magneto-optical disk, a CD-ROM, a CD-R, a nonvolatile memory card, etc. In addition to an operating system (OS) and various parameters, programs for operating the computer 70, etc. are recorded in this nonvolatile storage 74.

[0051] The program is stored in the form of a computer-readable program code, and the CPU 71 sequentially executes operations in accordance with the program code. In other words, the ROM 72 or the non-volatile storage 74 is used as an example of a computer-readable non-transitory recording medium that stores a program to be executed by a computer.

[0052] In FIG. 2, the overall control device 21 and the storage unit 22 are shown separately, but the function of the storage unit 22 may be realized by the non-volatile storage 74.

[0053] The communication interface 75 is configured by a communication device that controls communication with other devices, such as a user interface that accepts instructions from an engineer, a control device for a bending electromagnet, a charged particle beam generator, etc.

[0054] Networks for which the communication interface 75 performs communication control include, for example, multi-drop serial communication such as RS-485, and communication paths that provide multiple topologies such as Ethernet (registered trademark). Communication paths that provide multiple topologies include wired communication paths such as LAN (Local Area Network) and WAN (Wide Area Network), and wireless communication paths such as RAN (Radio Area Network). Furthermore, networks for which the communication interface 75 performs communication control include, for example, wireless paths such as Wi-Fi (registered trademark), and wireless paths in wireless communication infrastructures.

[0055] The control device for the bending electromagnet and the control device for the beam irradiation device can also be provided with a hardware configuration similar to that of the example in Fig. 4. In this case, in the control device for the bending electromagnet, the CPU 71 executes a computer program for realizing the function of changing the beam traveling direction, thereby realizing the function. Also, in the control device for beam irradiation, the CPU 71 executes a computer program for realizing the beam irradiation function (beam irradiation position control, etc.), thereby realizing the function.

[0056] Furthermore, the present invention is not limited to the above-described embodiments, and various other applications and modifications are possible without departing from the spirit of the present invention as set forth in the claims. For example, the above-described embodiments have been described in detail and specifically to clearly explain the present invention, and are not necessarily limited to those including all of the components described. Furthermore, it is also possible to add, replace, or delete other components to or from part of the configuration of the above-described embodiments.

[0057] In the above-described embodiment, the control lines and information lines are those that are considered necessary for the explanation, and not all control lines and information lines in the product are necessarily shown. In reality, it can be considered that almost all components are connected to each other.

[0058] Furthermore, although terms such as "orthogonal" and "vertical" are used in this specification, these terms do not mean only "orthogonal" and "vertical" in the strict sense, but also include the meanings of "orthogonal" and "vertical" in the strict sense, and further include the meanings of "approximately orthogonal" and "approximately vertical" within the range in which they can perform their functions. [Explanation of symbols]

[0059] 1...charged particle beam generator, 1-1 to 1-2...charged particle beam generator, 2...beam transport system, 3...beam irradiation device, 3-1 to 3-3...beam irradiation device, 6...bending electromagnet, 5...vacuum piping, 21...overall control device, 22...storage unit, 32...charged particle beam, 51-1 to 51-3, 52-1 to 52-2, 53-1 to 53-2, 54-1 to 54-2, 55...vacuum piping, 61-1 to 61-3, 62-1 to 62-2...bending electromagnet

Claims

1. two or more independently operable charged particle beam generators; a beam transport system that transports the charged particle beam generated by the charged particle beam generator; two or more beam irradiation devices to which the charged particle beam is transported by the beam transport system, Any one of the beam irradiation devices is configured to be able to transport beams from a plurality of the charged particle beam generators, and the charged particle beams are simultaneously transported from each of the plurality of charged particle beam generators to each of the corresponding different beam irradiation devices. Particle beam irradiation system.

2. The traveling direction of the first charged particle beam from the first charged particle beam generator to the first beam irradiation device and the traveling direction of the second charged particle beam from the second charged particle beam generator to the second beam irradiation device intersect at a point within the vacuum piping at a location where a bending electromagnet is arranged in the beam transport system. The particle beam irradiation system according to claim 1 .

3. The charged particle beam generator has different ion sources.

3. The particle beam irradiation system according to claim 1 or 2.

4. A particle beam irradiation method using a particle beam irradiation system including two or more independently operable charged particle beam generators, a beam transport system that transports the charged particle beams generated by the charged particle beam generators, and two or more beam irradiation devices to which the charged particle beams are transported by the beam transport system, comprising: Any one of the beam irradiation devices is configured to be able to transport beams from a plurality of the charged particle beam generators, and the charged particle beams are simultaneously transported from each of the plurality of charged particle beam generators to each of the corresponding different beam irradiation devices. Particle beam irradiation method.

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