Determination device, determination method, and program
The determination device and method address the challenge of diagnosing PPPD by analyzing center of gravity changes under visual stimulus, enhancing diagnostic accuracy and treatment efficacy.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- NIIGATA UNIVERSITY
- Filing Date
- 2022-05-02
- Publication Date
- 2026-05-25
AI Technical Summary
Persistent postural perceptual dizziness (PPPD) is difficult to diagnose due to a lack of specific tests, leading to inadequate treatment and reduced quality of life for affected patients, and existing balance function tests are unsuitable for differential diagnosis.
A determination device and method that uses visual stimulus loads to acquire load data, create scatter data of center of gravity coordinates, and determine the possibility of a dizziness disorder by analyzing the area or density of these coordinates before and after applying visual stimuli such as checker or linear patterns.
Provides a reliable method to assess the likelihood of dizziness disorders, particularly PPPD, by quantifying changes in center of gravity positions, improving diagnostic accuracy and patient treatment outcomes.
Smart Images

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Abstract
Description
Technical Field
[0001] Embodiments of the present invention relate to a determination device, a determination method, and a program.
Background Art
[0002] Persistent Postural Perceptual Dizziness (PPPD) is a disease mainly characterized by a floating feeling, a sense of instability, and non-rotary dizziness that persists for more than three months. The symptoms are aggravated by standing postures, active or passive body movements, moving objects, or seeing complex visual patterns. It is considered that many PPPD patients are included among patients who are diagnosed with dizziness after suffering from some vestibular disease, neurological or medical disease, or balance disorder due to psychological stress. There are no specific findings in balance function tests or brain imaging tests, and the diagnosis is based on a detailed interview regarding subjective symptoms, but the diagnosis is often difficult.
[0003] Regarding the evaluation of balance function by a stabilometer, there is a calibration method that is more consistent with the actual usage of the stabilometer and has higher accuracy (see, for example, Patent Document 1). Also, in a dynamic balance function test using a stabilometer, a stabilometer measurement system capable of quantifying fluctuations is known (see, for example, Patent Document 2).
Prior Art Documents
Patent Documents
[0004]
Patent Document 1
Patent Document 2
Summary of the Invention
Problems to be Solved by the Invention
[0005] Persistent postural vertigo (PPPD) accounts for 40% of chronic vertigo cases, and because dizziness and unsteadiness symptoms persist for a long period, it significantly reduces the quality of life (QoL) of affected patients. Since there is no test that shows findings specific to this disease, diagnosis is made through a detailed medical history of characteristic symptoms, but diagnoses often differ among medical professionals. As a result, patients may not receive adequate treatment, and the decline in symptoms and QoL continues, resulting in disadvantages for the patients. While measurements using a posturography system were useful for evaluating changes in an individual patient's balance function over time, they were unsuitable for the differential diagnosis of dizziness, including PPPD.
[0006] The object of the present invention is to provide a determination device, determination method, and program that can determine the possibility of a subject having a dizziness disorder. [Means for solving the problem]
[0007] One embodiment of the present invention includes an acquisition unit that acquires load data of a subject when a visual stimulus load is applied to the subject, a creation unit that creates scatter data of the subject's center of gravity coordinates based on the load data acquired by the acquisition unit, and the creation unit that creates the The above coordinates of the centroid The system comprises a determination unit that determines the possibility of a subject having a dizziness disorder based on scattered data, the visual stimulus load includes a first visual stimulus load that displays a checker pattern that inverts at predetermined intervals in front of the subject's eyes, the acquisition unit acquires the subject's first load data when the subject is given the first visual stimulus load, the creation unit creates first scattered data of the subject's center of gravity coordinates based on the first load data acquired by the acquisition unit, and the determination unit determines the first scattered data created by the creation unit. Based on the scattered data of the center of gravity position before the subject was given the visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity position before the subject was given the visual stimulus load and the area of the outer perimeter of the first scattered data are derived, and the area of the outer perimeter of the first scattered data of the center of gravity coordinates and the area of the outer perimeter of the scattered data of the center of gravity position before the subject was given the visual stimulus load and This is a determination device that determines the possibility of a dizziness disorder in the subject based on the above. One embodiment of the present invention is the determination device described above, wherein the visual stimulus load further includes a second visual stimulus load that displays a linear pattern moving in front of the subject's eyes at a predetermined speed, the acquisition unit acquires the subject's second load data when the subject is given the second visual stimulus load, the creation unit creates second scatter data of the subject's center of gravity coordinates based on the second load data acquired by the acquisition unit, and the determination unit uses the second scatter data created by the creation unit to determine the subject's center of gravity coordinates. Based on the scattered data of the center of gravity position before the subject is given the visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load and the area of the outer perimeter of the second scattered data are derived, and Centroid coordinates The area of the outer perimeter of the second scattered data, and the area of the outer perimeter of the scattered data of the center of gravity position before the subject was given the visual stimulus load. Based on this, the possibility of the subject having a dizziness disorder is determined. One embodiment of the present invention is the determination device described above, wherein the visual stimulus load further includes a third visual stimulus load that displays a dot pattern moving in front of the subject's eyes at a predetermined speed, the acquisition unit acquires the subject's third load data when the subject is given the third visual stimulus load, the creation unit creates third scatter data of the subject's center of gravity coordinates based on the third load data acquired by the acquisition unit, and the determination unit uses the third scatter data created by the creation unit to determine the subject's center of gravity coordinates. Based on the scattered data of the center of gravity position before the subject is given the visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load and the area of the outer perimeter of the third scattered data are derived, and Centroid coordinates The area of the outer perimeter of the third scattered data, and the area of the outer perimeter of the scattered data of the center of gravity position before the subject was given the visual stimulus load. Based on this, the possibility of the subject having a dizziness disorder is determined. 。 Book In one embodiment of the invention, in the aforementioned determination device, the determination unit determines the possibility of the subject having a dizziness disorder based on the density of the scatter data of the subject's centroid coordinates. One embodiment of the present invention is the determination device described above, in which the determination unit determines the possibility of the subject having persistent postural dizziness disorder based on the scatter data of the subject's center of gravity coordinates.
[0008] One embodiment of the present invention is a determination method performed by a computer, comprising the steps of: acquiring load data of a subject when a visual stimulus load is applied to the subject; creating scatter data based on the load data acquired in the acquisition step; and creating the The above coordinates of the centroidThe procedure includes a step of determining the possibility of a dizziness disorder in the subject based on the subject's center of gravity coordinates, wherein the visual stimulus load includes a first visual stimulus load that displays a checker pattern that inverts at predetermined intervals in front of the subject's eyes, the acquisition step involves acquiring first load data of the subject when the subject is given the first visual stimulus load, the creation step involves creating first scatter data of the subject's center of gravity coordinates based on the first load data acquired in the acquisition step, and the determination step involves determining the first scatter data created in the creation step Based on the scattered data of the center of gravity position before the subject is given the visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load and the area of the outer perimeter of the first scattered data are derived, and Centroid coordinates The area of the outer perimeter of the first scattered data, and the area of the outer perimeter of the scattered data of the center of gravity position before the subject was given the visual stimulus load. This is a computer-based determination method that determines the likelihood of a subject having a dizziness disorder based on the above.
[0009] One embodiment of the present invention provides a computer with the steps of: acquiring load data of a subject when a visual stimulus load is applied to the subject; creating scatter data of the subject's center of gravity coordinates based on the load data acquired in the acquisition step; and creating the The above coordinates of the centroid The procedure involves performing the steps of determining the possibility of a dizziness disorder in the subject based on the scatter data, the visual stimulus load includes a first visual stimulus load that displays a checker pattern that inverts at predetermined intervals in front of the subject's eyes, the acquisition step involves acquiring first load data of the subject when the subject is given the first visual stimulus load, the creation step involves creating first scatter data of the subject's center of gravity coordinates based on the first load data acquired in the acquisition step, and the determination step involves performing the first scatter data created in the creation step Based on the scattered data of the center of gravity position before the subject is given the visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load and the area of the outer perimeter of the first scattered data are derived, and Centroid coordinates The area of the outer perimeter of the first scattered data, and the area of the outer perimeter of the scattered data of the center of gravity position before the subject was given the visual stimulus load. This program determines the likelihood of a dizziness disorder in the subject based on the following criteria. [Effects of the Invention]
[0010] According to embodiments of the present invention, a determination device, determination method, and program can be provided that can determine the possibility of a subject having a dizziness disorder. [Brief explanation of the drawing]
[0011] [Figure 1] This is a diagram showing an example of a determination system according to an embodiment of the present invention. [Figure 2] This is a diagram showing an example of the visual stimulus load of the determination system according to the present embodiment. [Figure 3] This is a diagram showing an example of a determination device according to the present embodiment. [Figure 4] This is a flowchart showing an example of the operation of the determination system according to the present embodiment. [Figure 5] This is a diagram showing an example of the visual stimulus load of the determination system according to Modification 1 of the embodiment. [Figure 6] This is a diagram showing an example of a determination device according to Modification 1 of the embodiment. [Figure 7] This is a flowchart showing an example of the operation of the determination system according to Modification 1 of the embodiment. [Figure 8] This is a diagram showing an example of the visual stimulus load of the determination system according to Modification 2 of the embodiment. [Figure 9] This is a diagram showing an example of a determination device according to Modification 2 of the embodiment. [Figure 10] This is a flowchart showing an example of the operation of the determination system according to Modification 2 of the embodiment. [Figure 11] This is a diagram showing an example of the derivation of the area of the outer periphery of the scatter data of the center-of-gravity position in the determination system according to Modification 2 of the embodiment. [Figure 12] This is a diagram showing an example of the derivation of the density of the center-of-gravity position in the determination system according to Modification 2 of the embodiment. [[ID=三十八]] [Figure 13A] This is a diagram showing an example of the derivation of the scatter data of the center-of-gravity position in the determination system according to Modification 2 of the embodiment. [Figure 13B] [[ID=四十三]]This is a diagram showing an example of the derivation of the scatter data of the center-of-gravity position in the determination system according to Modification 2 of the embodiment.
Embodiments for Carrying Out the Invention
[0012] Next, a determination device, determination method, and program according to an embodiment of the present invention will be described with reference to the drawings. The embodiments described below are merely examples, and the embodiments to which the present invention is applied are not limited to the embodiments described below. In all the figures used to illustrate the embodiments, components with the same function are given the same reference numerals, and repeated explanations are omitted. Furthermore, in this application, "based on XX" means "based on at least XX," and includes cases where it is based on another element in addition to XX. Also, "based on XX" is not limited to cases where XX is used directly, but also includes cases where it is based on something that has been calculated or processed from XX. "XX" is any element (for example, any information).
[0013] (Embodiment) (Judgment System) Hereinafter, a determination system according to an embodiment of the present invention will be described with reference to the drawings. Figure 1 shows an example of a determination system according to an embodiment of the present invention. In Figure 1, the horizontal plane is represented by the X-axis and Y-axis directions, and the direction perpendicular to the X-axis and Y-axis directions is the Z-axis direction. The direction of the arrows in the figure is the positive direction, and the opposite direction is the negative direction. The determination system 1 according to this embodiment applies a visual stimulus load to subject SU. The determination system 1 acquires multiple load data of subject SU before applying the visual stimulus load and multiple load data of subject SU after applying the visual stimulus load. The load data is measured for a certain period of time by a posturograph to evaluate the upright posture of subject SU. An example of a certain period of time is 30 seconds or more and less than 90 seconds, with 45 seconds or more and less than 75 seconds being preferred. The judgment system 1 calculates the center of gravity position on the horizontal plane based on multiple load data of subject SU before and after the visual stimulus load was applied to subject SU, and creates scatter data of the center of gravity position. The judgment system 1 determines the possibility of subject SU having a dizziness disorder based on the created scatter data of subject SU's center of gravity position before and after the visual stimulus load was applied to subject SU.
[0014] The assessment system 1 comprises a posturography meter 50, a projection unit 70, and a judgment device 100. Figure 1 shows the posturography meter 50, the projection unit 70, and the judgment device 100, as well as the subject SU, the assistant CA, the operator OP, and the chair CH. The posturography meter 50, the projection unit 70, the judgment device 100, and the chair CH are installed in the examination room LA. In examination room LA, subject SU sits on chair CH until the examination begins. When the examination begins, subject SU stands up and steps onto the center of gravity sway meter 50. Subject SU assumes an upright posture facing the positive side of the X-axis. Assistant CA assists subject SU during the examination as needed.
[0015] A wall is located at a distance L1 from the subject SU in the positive X-axis direction; this wall is designated as the projection area PA. An example of length L1 is 70cm to 90cm, with 75cm to 85cm being preferred. For example, the projection area PA is formed on a plane represented by the Y-axis and the Z-axis. The projection unit 70 is installed at a distance L3 from the projection area PA, in a direction away from the subject SU. An example of length L3 is 175 cm to 225 cm, with 190 cm to 210 cm being preferred.
[0016] The projection unit 70 projects a visual stimulus onto the projection area PA. An example of the projection unit 70 includes a projector PR and an operating computer OT. The operator OP operates the operating computer OT to project a visual stimulus with a length L2 in the Y-axis direction onto the projector PR connected to the operating computer OT. An example of length L2 is 80 cm to 100 cm, with 85 cm to 95 cm being preferred. An example of length L2 is set so that the visual stimulus is included within the field of view 2θ of both eyes E, with the field of view θ being set for one eye of the subject SU. An example of the length of the visual stimulus in the Z-axis direction is the same as length L2. The projection unit 70 can provide a visual stimulus load to the subject SU by projecting a visual stimulus onto the projection area PA.
[0017] Figure 2 shows an example of the visual stimulus load of the judgment system according to this embodiment. An example of the visual stimulus load is provided by displaying a checker pattern that reverses at predetermined intervals in front of the subject's eyes. An example of the visual stimulus is a video in which the checker pattern moves to the positive or negative side of the Y-axis direction at predetermined intervals, so that it reverses at predetermined intervals. An example of movement at predetermined intervals is when the angle Φ is the angle between the line connecting subject SU and a predetermined point on the visual stimulus and the line connecting subject SU and the predetermined point on the visual stimulus after 1 second, the angle Φ is between 3 and 9 degrees, and preferably between 4.5 and 7.5 degrees. An example of the checker pattern is a grid of two-color (light and dark) squares arranged alternately in 8 vertical columns and 12 horizontal columns. An example of the two colors is white and black. The combination of the two colors and the number of squares can be changed as appropriate. Return to Figure 1 and continue the explanation.
[0018] The center of gravity sway meter 50 measures the load data of the subject SU. The center of gravity sway meter 50 measures the load data of the subject SU at predetermined intervals and outputs the measurement results of the subject SU's load data to the judgment device 100. An example of a predetermined interval is 25 milliseconds or more and less than 75 milliseconds, with 40 milliseconds or more and less than 60 milliseconds being preferred. The measurement results of the subject SU's load data include multiple load data of the subject SU before the subject SU is subjected to a visual stimulus load, and multiple load data of the subject SU after the subject SU is subjected to a visual stimulus load. Here, the load data of the subject SU after the subject SU is subjected to a visual stimulus load may include the load data of the subject SU while the subject SU is being subjected to a visual stimulus load.
[0019] Figure 3 shows an example of a determination device according to this embodiment. The determination device 100 is implemented by a device such as a personal computer, server, smartphone, tablet computer, or industrial computer. The determination device 100 includes, for example, an input unit 101, an acquisition unit 102, a creation unit 104, a determination unit 106, an output unit 108, and a storage unit 110.
[0020] The input unit 101 is equipped with an input device. The input unit 101 receives load data from subject SU. For example, the input unit 101 receives multiple load data from subject SU before the visual stimulus load is applied to subject SU, and multiple load data from subject SU after the visual stimulus load is applied to subject SU.
[0021] The acquisition unit 102 acquires multiple load data of subject SU input to the input unit 101. For load data of subject SU before subject SU is subjected to a visual stimulus load, the acquisition unit 102 stores the acquired load data of subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU has not yet been subjected to a visual stimulus load. For load data of subject SU after subject SU has been subjected to a visual stimulus load, the acquisition unit 102 stores the acquired load data of subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU has already been subjected to a visual stimulus load.
[0022] The creation unit 104 acquires multiple load data of subject SU from the storage unit 110. Based on the acquired multiple load data of subject SU, the creation unit 104 creates scatter data of multiple center of gravity positions of subject SU. For example, the creation unit 104 obtains from the storage unit 110 identification information of the subject SU, multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, and information indicating that the visual stimulus load has not yet been applied to the subject SU. Based on the multiple load data of the subject SU before the visual stimulus load is applied to the acquired subject SU, the creation unit 104 calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions before the visual stimulus load is applied to the subject SU. The creation unit 104 obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after a visual stimulus load has been applied to the subject SU, and information indicating that a visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after a visual stimulus load has been applied, the creation unit 104 calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after a visual stimulus load has been applied to the subject SU.
[0023] The determination unit 106 acquires scatter data of the subject SU's center of gravity from the creation unit 104. Based on the acquired scatter data of the subject SU's center of gravity, the determination unit 106 determines the possibility of the subject SU having a dizziness disorder. For example, the determination unit 106 acquires from the creation unit 104 scatter data of the subject SU's center of gravity before the subject SU is subjected to a visual stimulus load, and scatter data of the subject SU's center of gravity after the subject SU is subjected to a visual stimulus load. The determination unit 106 derives the area of the outer perimeter of the scatter data of the center of gravity before the visual stimulus load is applied to the subject SU and the area of the outer perimeter of the scatter data of the center of gravity after the visual stimulus load is applied to the subject SU, based on the acquired scatter data of the center of gravity position before the visual stimulus load is applied to the subject SU and the scatter data of the center of gravity position after the visual stimulus load is applied to the subject SU. Here, the area of the outer perimeter is the area enclosed by the outer perimeter determined by the trajectory of the center of gravity position. The determination unit 106 determines, based on the area of the outer perimeter of the scattered data of the center of gravity position before the subject SU is subjected to a visual stimulus load and the area of the outer perimeter of the scattered data of the center of gravity position after the subject SU is subjected to a visual stimulus load, that the subject SU may have a dizziness disorder such as persistent postural vertigo (PPPD) if the area of the outer perimeter of the scattered data of the center of gravity position after the subject SU is subjected to a visual stimulus load increases by a first area threshold or more compared to the area of the outer perimeter of the scattered data of the center of gravity position before the subject SU is subjected to a visual stimulus load. Based on the area of the outer perimeter of the derived scatter data of the center of gravity position, the determination unit 106 determines that subject SU does not have a possibility of having a dizziness disorder such as PPPD if the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a visual stimulus load does not increase by more than a first area threshold compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load.
[0024] The output unit 108 obtains the determination result regarding the possibility of dizziness disorder in subject SU from the determination unit 106. The output unit 108 outputs the obtained determination result regarding the possibility of dizziness disorder in subject SU. For example, the output unit 108 may output the determination result regarding the possibility of dizziness disorder in subject SU as audio, or it may output it to a display unit (not shown).
[0025] Furthermore, all or part of the input unit 101, acquisition unit 102, creation unit 104, determination unit 106, and output unit 108 are functional units (hereinafter referred to as software functional units) that are realized by a processor such as a CPU (Central Processing Unit) executing a program stored in the memory unit 110. Furthermore, all or part of the input unit 101, acquisition unit 102, creation unit 104, determination unit 106, and output unit 108 may be implemented by hardware such as an LSI (Large Scale Integration), ASIC (Application Specific Integrated Circuit), or FPGA (Field-Programmable Gate Array), or by a combination of software functions and hardware.
[0026] (Operation of the judgment system) Figure 4 is a flowchart showing an example of the operation of the determination system according to this embodiment. The operation of the determination device 100 included in the determination system 1 will be explained with reference to Figure 4. (Step S1-1) Multiple load data of subject SU from the center of gravity sway meter 50 are input to the input unit 101 of the judgment device 100. For example, multiple load data of subject SU before the visual stimulus load is applied to subject SU are input to the input unit 101, and multiple load data of subject SU after the visual stimulus load is applied to subject SU are input to the input unit 101.
[0027] (Step S2-1) The acquisition unit 102 of the determination device 100 acquires multiple load data of subject SU input to the input unit 101. The acquisition unit 102 associates the acquired load data of subject SU with the subject SU's identification information and information indicating that the subject SU has not yet been subjected to a visual stimulus load, and stores it in the storage unit 110. The acquisition unit 102 associates the acquired load data of subject SU with the subject SU's identification information and information indicating that the subject SU has already been subjected to a visual stimulus load, and stores it in the storage unit 110.
[0028] (Step S3-1) The creation unit 104 of the determination device 100 acquires identification information of the subject SU, multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, and information indicating that the visual stimulus load has not yet been applied to the subject SU from the storage unit 110. Based on each of the acquired multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, the creation unit 104 calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions before the visual stimulus load is applied to the subject SU. The creation unit 104 obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after a visual stimulus load has been applied to the subject SU, and information indicating that a visual stimulus load has been applied to the subject SU. Based on each of the multiple load data of the subject SU after a visual stimulus load has been applied to the subject SU obtained from the creation unit 104, the creation unit 104 calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after a visual stimulus load has been applied to the subject SU.
[0029] (Step S4-1) The determination unit 106 of the determination device 100 acquires from the creation unit 104 scatter data of the center of gravity position before the subject SU is subjected to a visual stimulus load and scatter data of the center of gravity position after the subject SU is subjected to a visual stimulus load. Based on the acquired scatter data of the center of gravity position before the subject SU is subjected to a visual stimulus load and scatter data of the center of gravity position after the subject SU is subjected to a visual stimulus load, the determination unit 106 derives the area of the outer perimeter of the scatter data of the center of gravity position before the subject SU is subjected to a visual stimulus load and the area of the outer perimeter of the scatter data of the center of gravity position after the subject SU is subjected to a visual stimulus load.
[0030] (Step S5-1) The determination unit 106 of the determination device 100 determines, based on the area of the outer perimeter of the scattered data of the centroid position before the subject SU is given a visual stimulus load and the area of the outer perimeter of the scattered data of the centroid position after the subject SU is given a visual stimulus load, whether the area of the outer perimeter of the scattered data of the centroid position after the subject SU is given a visual stimulus load has increased by a first area threshold or more compared to the area of the outer perimeter of the scattered data of the centroid position before the subject SU is given a visual stimulus load.
[0031] (Step S6-1) The determination unit 106 of the determination device 100 determines that subject SU may have a dizziness disorder if it determines that the area of the outer perimeter of the scattered data of the center of gravity position after subject SU has been subjected to a visual stimulus load has increased by a first area threshold or more compared to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU has been subjected to a visual stimulus load.
[0032] (Step S7-1) The determination unit 106 of the determination device 100 determines that subject SU does not have a dizziness disorder if it determines that the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is subjected to a visual stimulus load does not increase by more than a first area threshold compared to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is subjected to a visual stimulus load.
[0033] (Step S8-1) The output unit 108 of the determination device 100 obtains a determination result from the determination unit 106 regarding whether or not subject SU may have a dizziness disorder. The output unit 108 outputs the obtained determination result regarding the possibility of subject SU having a dizziness disorder.
[0034] In the embodiments described above, an example of visual stimulus load was explained in which a checker pattern is displayed in front of the subject's eyes as a video that moves in the positive or negative direction along the Y axis at predetermined intervals, causing it to reverse at predetermined intervals. However, the invention is not limited to this example. For example, it is not limited to a pattern of alternating two-colored squares arranged vertically and horizontally, but may also be a pattern of alternating two-colored circles or polygons arranged vertically and horizontally. As an example of visual stimulus load, a checker pattern may also be displayed in front of the subject's eyes as a video that moves in the positive or negative direction along the Z axis at predetermined intervals. As an example of a visual stimulus load, the load may be provided by displaying a video in front of the subject showing a checker pattern moving diagonally at predetermined intervals. Specifically, as an example of a visual stimulus load, the load may be provided by displaying a checker pattern in front of the subject showing an angle greater than 0 degrees and less than 90 degrees from the positive side of the Y-axis to the positive side of the Z-axis at predetermined intervals. As an example of a visual stimulus load, the load may be provided by displaying a checker pattern in front of the subject showing an angle greater than 0 degrees and less than 90 degrees from the negative side of the Y-axis to the negative side of the Z-axis at predetermined intervals. As an example of a visual stimulus load, the visual stimulus load may be provided by displaying a checker pattern in front of the subject's eyes that moves at predetermined intervals from the negative side of the Y-axis to the positive side of the Z-axis in an angle greater than 0 degrees but less than 90 degrees. Furthermore, any of the aforementioned examples of visual stimulus loads may be combined. In the embodiment described above, the case in which multiple load data of subject SU before the visual stimulus load is applied to subject SU is input to the input unit 101 of the determination device 100, and multiple load data of subject SU after the visual stimulus load is applied to subject SU is input, was described, but the invention is not limited to this example. For example, in the determination device 100, multiple load data of subject SU before the visual stimulus load is applied to subject SU may be pre-inputted. In this case, the creation unit 104 calculates multiple center of gravity positions of subject SU on the horizontal plane based on the multiple load data of subject SU before the visual stimulus load is applied to subject SU, and creates scatter data of the center of gravity positions before the visual stimulus load is applied to subject SU. By configuring it in this way, the process of acquiring multiple load data of subject SU before the visual stimulus load is applied to subject SU can be omitted, thus shortening the time required for the test.
[0035] In the embodiment described above, the determination unit 106 of the determination device 100 derives the area of the outer perimeter of the scatter data of the center of gravity before the subject SU is subjected to a visual stimulus load and the area of the outer perimeter of the scatter data of the center of gravity after the subject SU is subjected to a visual stimulus load, based on the scatter data of the center of gravity before the subject SU is subjected to a visual stimulus load and the scatter data of the center of gravity after the subject SU is subjected to a visual stimulus load. However, the invention is not limited to this example. For example, the determination unit 106 may derive the density of the center of gravity of the subject SU before and after the subject SU is subjected to a visual stimulus load, based on the scatter data of the center of gravity position before the subject SU is subjected to a visual stimulus load and the scatter data of the center of gravity position after the subject SU is subjected to a visual stimulus load.
[0036] For example, the determination unit 106 derives the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions before subject SU is given a visual stimulus load, and the area of the outer perimeter of the scattered data, and the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a visual stimulus load, and the area of the outer perimeter of the scattered data. The determination unit 106 derives the density of centroid positions before subject SU is subjected to visual stimulation by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions before subject SU is subjected to visual stimulation by the area of the outer perimeter of the scattered data. The determination unit 106 derives the density of centroid positions after subject SU is subjected to visual stimulation by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is subjected to visual stimulation by the area of the outer perimeter of the scattered data.
[0037] The determination unit 106 determines, based on the density of the center of gravity positions before the subject SU is subjected to a visual stimulus load and the density of the center of gravity positions after the subject SU is subjected to a visual stimulus load, whether the density of the center of gravity positions after the subject SU is subjected to a visual stimulus load has decreased by a first density threshold or more compared to the density of the center of gravity positions before the subject SU is subjected to a visual stimulus load. The determination unit 106 determines that subject SU may have a dizziness disorder if it determines that the density of the center of gravity positions after subject SU is subjected to a visual stimulus load has decreased by a first density threshold or more compared to the density of the center of gravity positions before subject SU is subjected to a visual stimulus load. The determination unit 106 determines that subject SU does not have a dizziness disorder if it determines that the density of the center of gravity positions after subject SU is subjected to a visual stimulus load does not decrease by more than a first density threshold compared to the density of the center of gravity positions before subject SU is subjected to a visual stimulus load. The conditions for determining whether subject SU has a dizziness disorder can be set as appropriate. In the embodiment described above, the determination unit 106 may be configured to determine whether or not the condition is PPPD, which is included in dizziness disorders. For example, the first area threshold may be set to determine whether or not it is PPPD or a dizziness disorder other than PPPD. Alternatively, by setting the first density threshold to allow determination of whether it is PPPD or a dizziness disorder other than PPPD, the determination unit 106 may determine whether or not it is PPPD, which is included in dizziness disorders.
[0038] According to the determination system 1 of this embodiment, the determination device 100 includes an acquisition unit 102 that acquires load data of subject SU when a visual stimulus load is applied to subject SU, a creation unit 104 that creates scatter data of the subject's center of gravity coordinates based on the load data acquired by the acquisition unit 102, and a determination unit 106 that determines the possibility of subject SU having a dizziness disorder based on the scatter data created by the creation unit 104. The visual stimulus load includes a first visual stimulus load that displays a checker pattern that reverses at predetermined intervals in front of subject SU's eyes, the acquisition unit 102 acquires first load data of subject SU when the first visual stimulus load is applied to subject SU, the creation unit 104 creates first scatter data of the subject's center of gravity coordinates based on the first load data acquired by the acquisition unit 102, and the determination unit 106 determines the possibility of subject SU having a dizziness disorder based on the first scatter data created by the creation unit 104.
[0039] By configuring it in this way, the determination device 100 can acquire multiple load data of subject SU when a first visual stimulus load is applied, which displays a checker pattern that reverses at predetermined intervals in front of the subject SU's eyes. Based on the acquired load data, it can create scatter data of the subject's center of gravity coordinates, and based on the created scatter data, it can determine the possibility of dizziness disorder in subject SU.
[0040] In the determination device 100, the determination unit 106 determines the possibility of dizziness disorder in subject SU based on the area of the outer perimeter of the scatter data of the subject's centroid coordinates. By configuring it in this way, the determination device 100 can derive the area of the outer perimeter of the scatter data of the subject's centroid coordinates, and based on the area of the outer perimeter of the derived scatter data, it can determine the possibility of subject SU having a dizziness disorder.
[0041] In the determination device 100, the determination unit 106 determines the possibility of dizziness disorder in subject SU based on the density of the scattered data of the subject's centroid coordinates. By configuring it in this way, the determination device 100 can derive the density of the scatter data of the subject's centroid coordinates, and based on the density of the derived scatter data, it can determine the possibility of subject SU having a dizziness disorder. In the determination device 100, the determination unit 106 determines the possibility of subject SU having persistent postural dizziness disorder based on the scattered data. By configuring it in this way, the determination device 100 can determine the possibility that subject SU has persistent postural-induced vertigo disorder.
[0042] (Modification of Embodiment 1) (Judgment System) An example of the determination system 1a according to the modified embodiment 1 is applicable to Figure 1, except that it includes a determination device 100a instead of the determination device 100. Furthermore, the projection unit 70 projects a linear pattern moving at a predetermined speed onto the projection area PA, in addition to a checker pattern that reverses at predetermined time intervals.
[0043] Figure 5 shows an example of the visual stimulus load of the judgment system according to Modification 1 of the Embodiment. An example of the visual stimulus load is provided by displaying a linear pattern moving at a predetermined speed in front of the subject's eyes. The linear pattern has multiple black lines formed in the vertical direction (Z-axis direction). An example of the visual stimulus is the display of a video in which the linear pattern moves at a predetermined speed in the positive or negative direction of the Y-axis, reversing at predetermined time intervals and moving at the predetermined speed. An example of the predetermined speed is when the angle Φ is the angle between the line connecting the subject SU and a predetermined point on the visual stimulus and the line connecting the subject SU and the predetermined point on the visual stimulus after 1 second, the angle Φ is between 3 and 9 degrees, and preferably between 4.5 and 7.5 degrees. An example of the linear pattern is 23 rows of alternating stripes of two colors (light and dark). In other words, an example of the linear pattern is 12 dark (black) lines. An example of the two colors is white and black. The combination of two colors and the number of stripes can be changed as needed.
[0044] Figure 6 shows an example of a determination device according to modified embodiment 1. The determination device 100a is implemented by a device such as a personal computer, server, smartphone, tablet computer, or industrial computer. The determination device 100a includes, for example, an input unit 101a, an acquisition unit 102a, a creation unit 104a, a determination unit 106a, an output unit 108, and a storage unit 110.
[0045] The input unit 101a is equipped with an input device. Multiple load data of subject SU are input to the input unit 101a. For example, multiple load data of subject SU before subject SU is given a visual stimulus load are input to the input unit 101a, and multiple load data of subject SU after subject SU is given a visual stimulus load are input to the input unit 101a. The load data of subject SU after subject SU is given a visual stimulus load may include the load data of subject SU while subject SU is being given a visual stimulus load. Here, the visual stimulus load includes a load given by displaying a checker pattern that reverses at predetermined time intervals in front of the subject's eyes (hereinafter referred to as the "first visual stimulus load") and a load given by displaying a linear pattern that moves at a predetermined speed in front of the subject's eyes (hereinafter referred to as the "second visual stimulus load").
[0046] The acquisition unit 102a acquires the load data of the subject SU input to the input unit 101a. The acquisition unit 102a stores the acquired load data of the subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU was not yet subjected to a visual stimulus load, for load data of the subject SU before the visual stimulus load was applied to the subject SU. The acquisition unit 102a stores the acquired load data of subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU has been subjected to the first visual stimulus load, for load data of subject SU after the first visual stimulus load has been applied to subject SU. The acquisition unit 102a stores the acquired load data of subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU has been subjected to a second visual stimulus load, for load data of subject SU after a second visual stimulus load has been applied to subject SU.
[0047] The creation unit 104a acquires multiple load data of the subject SU from the storage unit 110. Based on the acquired multiple load data of the subject SU, the creation unit 104a calculates the position of the center of gravity of the subject SU on the horizontal plane and creates scatter data of the center of gravity of the subject SU. For example, the creation unit 104a obtains from the storage unit 110 identification information of the subject SU, multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, and information indicating that the visual stimulus load has not yet been applied to the subject SU. Based on the multiple load data of the subject SU before the visual stimulus load is applied to the acquired subject SU, the creation unit 104a calculates the position of the center of gravity of the subject SU on the horizontal plane and creates scatter data of the position of the center of gravity before the visual stimulus load is applied to the subject SU.
[0048] The creation unit 104a obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the first visual stimulus load has been applied to the subject SU, and information indicating that the first visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after the first visual stimulus load has been applied, the creation unit 104a calculates the position of the center of gravity of the subject SU on the horizontal plane and creates scatter data of the position of the center of gravity after the first visual stimulus load has been applied to the subject SU.
[0049] The creation unit 104a obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the second visual stimulus load has been applied to the subject SU, and information indicating that the second visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after the second visual stimulus load has been applied, the creation unit 104a calculates the position of the center of gravity of the subject SU on the horizontal plane and creates scatter data of the position of the center of gravity after the second visual stimulus load has been applied to the subject SU.
[0050] The determination unit 106a acquires scatter data of the center of gravity position from the creation unit 104a. Based on the acquired scatter data, the determination unit 106a determines the possibility of dizziness disorder in subject SU. For example, the determination unit 106a derives the area of the outer perimeter of the scatter data of the centroid position before subject SU is given a visual stimulus load, the area of the outer perimeter of the scatter data of the centroid position after subject SU is given a first visual stimulus load, and the area of the outer perimeter of the scatter data of the centroid position after subject SU is given a second visual stimulus load.
[0051] The determination unit 106a determines whether the area of the outer perimeter of the scatter data of the centroid position when subject SU is given a first visual stimulus load has increased by a first threshold or more compared to the area of the outer perimeter of the scatter data of the centroid position when subject SU is not given a visual stimulus load. The determination unit 106a determines whether the area of the outer perimeter of the scatter data of the centroid position when subject SU is given a second visual stimulus load has increased by a second threshold or more compared to the area of the outer perimeter of the scatter data of the centroid position when subject SU is not given a visual stimulus load.
[0052] The determination unit 106a determines whether subject SU may have a dizziness disorder based on the determination result of whether the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a first visual stimulus load has increased by a first threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load, and the determination result of whether the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a second visual stimulus load has increased by a second threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load.
[0053] For example, the determination unit 106a determines that subject SU may have a dizziness disorder if at least one of the following conditions is met: the area of the outer perimeter of the scatter data of the center of gravity when subject SU is given a first visual stimulus load increases by a first threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity when subject SU is not given a visual stimulus load; or the area of the outer perimeter of the scatter data of the center of gravity when subject SU is given a second visual stimulus load increases by a second threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity when subject SU is not given a visual stimulus load.
[0054] For example, the determination unit 106a determines that subject SU does not have a dizziness disorder if both conditions are met: the area of the outer perimeter of the scatter data of the center of gravity when subject SU is given a first visual stimulus load does not increase by a first threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity when subject SU is not given a visual stimulus load; and the area of the outer perimeter of the scatter data of the center of gravity when subject SU is given a second visual stimulus load does not increase by a second threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity when subject SU is not given a visual stimulus load.
[0055] Furthermore, all or part of the input unit 101a, acquisition unit 102a, creation unit 104a, and determination unit 106a are functional units (hereinafter referred to as software functional units) that are realized, for example, by a processor such as a CPU executing a program stored in the storage unit 110. Furthermore, all or part of the input unit 101a, acquisition unit 102a, creation unit 104a, and determination unit 106a may be implemented by hardware such as an LSI, ASIC, or FPGA, or by a combination of software functions and hardware.
[0056] (Operation of the judgment system) Figure 7 is a flowchart showing an example of the operation of the determination system according to modified embodiment 1. The operation of the determination device 100a of the determination system 1a will be described with reference to Figure 7. (Step S1-2) Multiple load data of subject SU from the center of gravity sway meter 50 are input to the input unit 101a of the judgment device 100a. For example, multiple load data of subject SU before subject SU is given a visual stimulus load are input to the input unit 101a, multiple load data of subject SU after subject SU is given a first visual stimulus load are input to subject SU, and multiple load data of subject SU after subject SU is given a second visual stimulus load are input to subject SU.
[0057] (Step S2-2) The acquisition unit 102a of the determination device 100a acquires multiple load data of subject SU input to the input unit 101a. From the acquired multiple load data of subject SU, the acquisition unit 102a associates the multiple load data of subject SU before the visual stimulus load is applied to subject SU, the identification information of subject SU, and information indicating that the visual stimulus load has not yet been applied to subject SU, and stores them in the storage unit 110. The acquisition unit 102a associates multiple load data of the subject SU after the first visual stimulus load has been applied to the subject SU, along with the subject SU's identification information and information indicating that the first visual stimulus load has been applied to the subject SU, and stores this information in the storage unit 110. The acquisition unit 102a associates multiple load data of the subject SU after the subject SU has been given a second visual stimulus load, the subject SU's identification information, and information indicating that the subject SU has been given a second visual stimulus load, and stores them in the storage unit 110.
[0058] (Step S3-2) The creation unit 104a of the determination device 100a acquires identification information of the subject SU, multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, and information indicating that the visual stimulus load has not yet been applied to the subject SU from the storage unit 110. Based on the acquired multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, the creation unit 104a calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions before the visual stimulus load is applied to the subject SU. The creation unit 104a obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the first visual stimulus load has been applied to the subject SU, and information indicating that the first visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after the first visual stimulus load has been applied, the creation unit 104a calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the first visual stimulus load has been applied to the subject SU. The creation unit 104a obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the second visual stimulus load has been applied to the subject SU, and information indicating that the second visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after the second visual stimulus load has been applied, the creation unit 104a calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the second visual stimulus load has been applied to the subject SU.
[0059] (Step S4-2) The determination unit 106a of the determination device 100a acquires from the creation unit 104a the scatter data of the center of gravity position before a visual stimulus load is applied to the subject SU, the scatter data of the center of gravity position after a first visual stimulus load is applied to the subject SU, and the scatter data of the center of gravity position after a second visual stimulus load is applied to the subject SU. Based on the acquired scatter data of the center of gravity position before a visual stimulus load is applied to the subject SU, the scatter data of the center of gravity position after a first visual stimulus load is applied to the subject SU, and the scatter data of the center of gravity position after a second visual stimulus load is applied to the subject SU, the determination unit 106a derives the area of the outer perimeter of the scatter data of the center of gravity position before a visual stimulus load is applied to the subject SU, the area of the outer perimeter of the center of gravity position after a first visual stimulus load is applied to the subject SU, and the area of the outer perimeter of the center of gravity position after a second visual stimulus load is applied to the subject SU.
[0060] (Step S5-2) The determination unit 106a of the determination device 100a determines, based on the area of the outer perimeter of the scattered data of the centroid position before the derived subject SU is given a visual stimulus load, the area of the outer perimeter of the scattered data of the centroid position after the subject SU is given a first visual stimulus load, and the area of the outer perimeter of the scattered data of the centroid position after the subject SU is given a second visual stimulus load, whether at least one of the following conditions is met: the area of the outer perimeter of the scattered data of the centroid position after the subject SU is given a first visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the centroid position before the subject SU is given a first visual stimulus load, and the area of the outer perimeter of the scattered data of the centroid position after the subject SU is given a second visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the centroid position after the subject SU is given a second visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the centroid position before the subject SU is given a second visual stimulus load.
[0061] (Step S6-2) The determination unit 106a of the determination device 100a determines that subject SU may have a dizziness disorder if it determines that at least one of the following conditions is met: the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a first visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a first visual stimulus load; or the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a second visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a second visual stimulus load.
[0062] (Step S7-2) The determination unit 106a of the determination device 100a determines that there is no possibility of a dizziness disorder in subject SU if it determines that both of the following conditions are met: the area of the outer perimeter of the scattered data of the center of gravity position after subject SU has been given a first visual stimulus load does not increase by more than a first area threshold compared to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU has been given a second visual stimulus load, and the area of the outer perimeter of the scattered data of the center of gravity position after subject SU has been given a second visual stimulus load does not increase by more than a second area threshold compared to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU has been given a second visual stimulus load.
[0063] (Step S8-2) The output unit 108 of the determination device 100a obtains a determination result from the determination unit 106a regarding whether or not subject SU may have a dizziness disorder. The output unit 108 outputs the obtained determination result regarding the possibility of subject SU having a dizziness disorder.
[0064] In the modified embodiment 1 described above, an example of a second visual stimulus load was described in which a linear pattern is displayed in front of the subject's eyes as a video moving at a predetermined speed in the positive or negative direction of the Y-axis. However, the invention is not limited to this example. For example, the linear pattern is not limited to a straight line, but may also be a wavy line or a zigzag line. As an example of a second visual stimulus load, a linear pattern may be displayed in front of the subject's eyes as a video moving at a predetermined speed in the positive or negative direction of the Z-axis. As an example of a second visual stimulus load, it may be provided by displaying a video in front of the subject showing a linear pattern moving diagonally at a predetermined speed. Specifically, as an example of a second visual stimulus load, it may be provided by displaying a linear pattern in front of the subject showing a linear pattern moving at a predetermined speed from the positive side of the Y-axis to the positive side of the Z-axis at an angle greater than 0 degrees and less than 90 degrees. As an example of a second visual stimulus load, it may be provided by displaying a linear pattern in front of the subject showing a linear pattern moving at a predetermined speed from the negative side of the Y-axis to the negative side of the Z-axis at an angle greater than 0 degrees and less than 90 degrees. As an example of a second visual stimulus load, the visual stimulus load may be provided by displaying a linear pattern in front of the subject's eyes at a predetermined speed, moving in an angle greater than 0 degrees and less than 90 degrees from the negative side of the Y-axis to the positive side of the Z-axis. Furthermore, any of the aforementioned examples of second visual stimulus loads may be combined. In the first modified embodiment, as an example, the determination unit 106a of the determination device 100a determined that subject SU may have a dizziness disorder when it determined that at least one of the following conditions is met: the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a first visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a first visual stimulus load; or the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a second visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a second visual stimulus load. However, the invention is not limited to this example. For example, the conditions for determining whether subject SU may have a dizziness disorder can be set as appropriate.
[0065] In the modified example 1 of the above-described embodiment, the determination device 100a describes a case in which the determination unit 106a derives the area of the outer perimeter of the scattered data of the center of gravity before the subject SU is given a visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity after the subject SU is given a first visual stimulus load, and the area of the outer perimeter of the scattered data of the center of gravity after the subject SU is given a second visual stimulus load, based on the scattered data of the center of gravity before the subject SU is given a visual stimulus load, the scattered data of the center of gravity after the subject SU is given a first visual stimulus load, and the scattered data of the center of gravity after the subject SU is given a second visual stimulus load. However, the invention is not limited to this example. For example, the determination unit 106a may derive the density of the center of gravity of subject SU before subject SU is given a visual stimulus load, the density of the center of gravity of subject SU after subject SU is given a first visual stimulus load, and the density of the center of gravity of subject SU after subject SU is given a second visual stimulus load, based on the scattered data of the center of gravity of subject SU before subject SU is given a visual stimulus load, the scattered data of the center of gravity of subject SU after subject SU is given a first visual stimulus load, and the scattered data of the center of gravity of subject SU after subject SU is given a second visual stimulus load.
[0066] For example, the determination unit 106a derives the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions before subject SU is given a visual stimulus load, the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a first visual stimulus load, the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a second visual stimulus load, and the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a second visual stimulus load.
[0067] The determination unit 106a derives the density of centroid positions before subject SU is given a visual stimulus load by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions before subject SU is given a visual stimulus load by the area of the outer perimeter of the scattered data. The determination unit 106a derives the density of centroid positions after subject SU is given a first visual stimulus load by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a first visual stimulus load by the area of the outer perimeter of the scattered data. The determination unit 106a derives the density of centroid positions after subject SU is given a second visual stimulus load by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a second visual stimulus load by the area of the outer perimeter of the scattered data.
[0068] The determination unit 106a determines, based on the density of the center of gravity positions before the subject SU is given a visual stimulus load and the density of the center of gravity positions after the subject SU is given a first visual stimulus load, whether the density of the center of gravity positions after the subject SU is given a first visual stimulus load has decreased by a first density threshold or more compared to the density of the center of gravity positions before the subject SU is given a first visual stimulus load. The determination unit 106a determines, based on the density of the center of gravity positions before the subject SU is given a visual stimulus load and the density of the center of gravity positions after the subject SU is given a second visual stimulus load, whether the density of the center of gravity positions after the subject SU is given a second visual stimulus load has decreased by more than the second density threshold compared to the density of the center of gravity positions before the subject SU is given a second visual stimulus load.
[0069] The determination unit 106a determines that subject SU may have a dizziness disorder if it determines that at least one of the following conditions is met: the density of the center of gravity positions after subject SU is given a first visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a visual stimulus load is lower than the density of the center of gravity positions after subject SU is given a second visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a after subject SU is given a visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a visual stimulus load is lower. The determination unit 106a determines that subject SU does not have a dizziness disorder if it determines that both of the following conditions are met: the density of the center of gravity after subject SU is given a first visual stimulus load does not decrease by more than a first density threshold compared to the density of the center of gravity before subject SU is given a visual stimulus load; and the density of the center of gravity after subject SU is given a second visual stimulus load does not decrease by more than a second density threshold compared to the density of the center of gravity before subject SU is given a visual stimulus load. The conditions for determining whether subject SU has a dizziness disorder can be set as appropriate.
[0070] In the modified example 1 of the above-described embodiment, the determination unit 106a may determine whether or not subject SU may have a dizziness disorder based on the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a visual stimulus load and the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a second visual stimulus load. For example, the determination unit 106a determines that subject SU may have a dizziness disorder if the area of the outer perimeter of the scatter data of the center of gravity after subject SU is given a second visual stimulus load is greater than or equal to the second area threshold compared to the area of the outer perimeter of the scatter data of the center of gravity before subject SU is given a visual stimulus load. For example, the determination unit 106a determines that subject SU does not have a dizziness disorder if the area of the outer perimeter of the scatter data of the center of gravity after subject SU is given a second visual stimulus load does not increase by more than a second area threshold compared to the area of the outer perimeter of the scatter data of the center of gravity before subject SU is given a visual stimulus load.
[0071] In the modified example 1 of the above-described embodiment, the determination unit 106a may be configured to determine whether or not the condition is PPPD, which is included in dizziness disorders. For example, the first area threshold and the second area threshold may be set to determine whether or not the condition is PPPD or a dizziness disorder other than PPPD. Alternatively, by setting the first density threshold and the second density threshold to determine whether it is PPPD or a dizziness disorder other than PPPD, the determination unit 106a may determine whether or not it is PPPD, which is included in dizziness disorders.
[0072] According to the determination system 1a of the modified embodiment 1, the determination device 100a further includes a second visual stimulus load in which a linear pattern that reverses at predetermined intervals is displayed in front of the eyes of the subject SU. The acquisition unit 102a acquires the subject SU's second load data when the subject SU is given the second visual stimulus load. The creation unit 104b creates second scatter data of the subject's center of gravity coordinates based on the second load data acquired by the acquisition unit 102b. The determination unit 106b further determines the possibility of the subject SU having a dizziness disorder based on the second scatter data created by the creation unit 104b.
[0073] By configuring it in this way, the determination device 100a can acquire multiple load data of subject SU when a second visual stimulus load is further applied, which displays a linear pattern moving at a predetermined speed in front of subject SU's eyes. Based on the acquired load data, it can create scatter data of the subject's center of gravity coordinates, and based on the created scatter data, it can determine the possibility of dizziness disorder in subject SU.
[0074] In the determination device 100a, the determination unit 106a determines the possibility of dizziness disorder in subject SU based on the area of the outer perimeter of the scatter data of the subject's centroid coordinates. By configuring it in this way, the determination device 100a can derive the area of the outer perimeter of the scatter data of the subject's centroid coordinates, and based on the area of the outer perimeter of the derived scatter data, it can determine the possibility of subject SU having a dizziness disorder.
[0075] In the determination device 100a, the determination unit 106a determines the possibility of dizziness disorder in subject SU based on the density of the scattered data of the subject's centroid coordinates. By configuring it in this way, the determination device 100a can derive the density of the scatter data of the subject's centroid coordinates, and based on the density of the derived scatter data, it can determine the possibility of subject SU having a dizziness disorder. In the determination device 100a, the determination unit 106a determines the possibility of subject SU having persistent postural dizziness disorder based on the scatter data of the subject's center of gravity coordinates. By configuring it in this way, the determination device 100a can determine the possibility of persistent postural dizziness disorder in subject SU.
[0076] (Modified embodiment 2) (Judgment System) An example of the determination system 1b according to the modified embodiment 2 is applicable to Figure 1, except that it includes a determination device 100b instead of the determination device 100. Furthermore, the projection unit 70 projects a dot pattern moving at a predetermined speed onto the projection area PA, in addition to a checker pattern that reverses at predetermined time intervals and a linear pattern that moves at a predetermined speed.
[0077] Figure 8 shows an example of a visual stimulus load for a determination system according to a modified example 2 of the embodiment. An example of a visual stimulus load is provided by displaying a dot pattern moving at a predetermined speed in front of the subject's eyes. An example of a visual stimulus is a video in which one or more dots move at a predetermined speed in the positive or negative direction of the X axis, so that the dot pattern containing one or more dots moves at a predetermined speed. For example, as time passes, the size of one or more dots changes so that it appears as if one or more dots are moving. An example of a dot pattern is a black background with multiple white dots randomly arranged. The background color and the dot color can be changed as appropriate.
[0078] Figure 9 shows an example of a determination device according to a modified example 2 of the embodiment. The determination device 100b is implemented by a device such as a personal computer, server, smartphone, tablet computer, or industrial computer. The determination device 100b includes, for example, an input unit 101b, an acquisition unit 102b, a creation unit 104b, a determination unit 106b, an output unit 108, and a storage unit 110.
[0079] The input unit 101b is equipped with an input device. Multiple load data of subject SU are input to the input unit 101b. For example, multiple load data of subject SU before subject SU is subjected to a visual stimulus load are input to the input unit 101b, and multiple load data of subject SU after subject SU is subjected to a visual stimulus load are input to the input unit 101b. The load data of subject SU after subject SU has been given a visual stimulus load may include the load data of subject SU while subject SU was being given the visual stimulus load. Here, the visual stimulus load includes a first visual stimulus load, a second visual stimulus load, and a load given by displaying a dot pattern moving at a predetermined speed in front of the subject's eyes (hereinafter referred to as the "third visual stimulus load"). The dot pattern moving at a predetermined speed is a dot pattern that moves over time, such as optical flow.
[0080] The acquisition unit 102b acquires multiple load data of the subject SU input to the input unit 101b. The acquisition unit 102b stores the acquired multiple load data of the subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU was not yet subjected to a visual stimulus load, for load data of the subject SU before the visual stimulus load was applied to the subject SU. The acquisition unit 102b stores the acquired load data of subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU has been subjected to the first visual stimulus load, for load data of subject SU after the first visual stimulus load has been applied to subject SU.
[0081] The acquisition unit 102b stores the acquired load data of subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU has been subjected to a second visual stimulus load, for load data of subject SU after a second visual stimulus load has been applied to subject SU. The acquisition unit 102b stores the acquired load data of subject SU in the storage unit 110, associating the subject SU's identification information with information indicating that the subject SU has been subjected to a third visual stimulus load, for load data of subject SU after the subject SU has been subjected to a third visual stimulus load.
[0082] The creation unit 104b acquires multiple load data of the subject SU from the storage unit 110. Based on the acquired load data of the subject SU, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions of the subject SU. For example, the creation unit 104b obtains from the storage unit 110 identification information of the subject SU, multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, and information indicating that the visual stimulus load has not yet been applied to the subject SU. Based on the multiple load data of the subject SU before the visual stimulus load is applied to the subject SU obtained, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions before the visual stimulus load is applied to the subject SU.
[0083] The creation unit 104b obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the first visual stimulus load has been applied to the subject SU, and information indicating that the first visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after the first visual stimulus load has been applied, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the first visual stimulus load has been applied to the subject SU.
[0084] The creation unit 104b obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the second visual stimulus load has been applied to the subject SU, and information indicating that the second visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after the second visual stimulus load has been applied, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the second visual stimulus load has been applied to the subject SU.
[0085] The creation unit 104b obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the third visual stimulus load has been applied to the subject SU, and information indicating that the third visual stimulus load has been applied to the subject SU. Based on the multiple load data of the subject SU after the third visual stimulus load has been applied, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the third visual stimulus load has been applied to the subject SU.
[0086] The determination unit 106b acquires scatter data of the center of gravity position from the creation unit 104b. Based on the acquired scatter data, the determination unit 106b determines the possibility of dizziness disorder in subject SU. For example, the determination unit 106b derives the area of the outer perimeter of the scatter data of the centroid position before subject SU is given a visual stimulus load, the area of the outer perimeter of the scatter data of the centroid position after subject SU is given a first visual stimulus load, the area of the outer perimeter of the scatter data of the centroid position after subject SU is given a second visual stimulus load, and the area of the outer perimeter of the scatter data of the centroid position after subject SU is given a third visual stimulus load.
[0087] The determination unit 106b determines whether the area of the outer perimeter of the scatter data of the centroid position when subject SU is given a first visual stimulus load has increased by a first threshold or more compared to the area of the outer perimeter of the scatter data of the centroid position when subject SU is not given a visual stimulus load. The determination unit 106b determines whether the area of the outer perimeter of the scatter data of the centroid position when subject SU is given a second visual stimulus load has increased by a second threshold or more compared to the area of the outer perimeter of the scatter data of the centroid position when subject SU is not given a visual stimulus load. The determination unit 106b determines whether the area of the outer perimeter of the scatter data of the centroid position when subject SU is given a third visual stimulus load has increased by a third threshold or more compared to the area of the outer perimeter of the scatter data of the centroid position when subject SU is not given a visual stimulus load.
[0088] The determination unit 106b determines whether subject SU may have a dizziness disorder based on the following: whether the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a first visual stimulus load has increased by a first threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load; whether the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a second visual stimulus load has increased by a second threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load; and whether the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a third visual stimulus load has increased by a third threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load.
[0089] For example, the determination unit 106b determines that subject SU may have a dizziness disorder if at least one of the following conditions is met: when the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a first visual stimulus load increases by a first threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load; when the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a second visual stimulus load increases by a second threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load; or when the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is given a third visual stimulus load increases by a third threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load.
[0090] For example, the determination unit 106b determines that subject SU does not have a dizziness disorder if all of the following conditions are met: when subject SU is given a first visual stimulus load, the area of the outer perimeter of the scatter data of the center of gravity position does not increase by a first threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load; when subject SU is given a second visual stimulus load, the area of the outer perimeter of the scatter data of the center of gravity position does not increase by a second threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load; and when subject SU is given a third visual stimulus load, the area of the outer perimeter of the scatter data of the center of gravity position does not increase by a third threshold or more compared to the area of the outer perimeter of the scatter data of the center of gravity position when subject SU is not given a visual stimulus load.
[0091] Furthermore, all or part of the input unit 101b, acquisition unit 102b, creation unit 104b, and determination unit 106b are functional units (hereinafter referred to as software functional units) that are realized, for example, by a processor such as a CPU executing a program stored in the storage unit 110. Furthermore, all or part of the input unit 101b, acquisition unit 102b, creation unit 104b, and determination unit 106b may be implemented by hardware such as an LSI, ASIC, or FPGA, or by a combination of software functions and hardware.
[0092] (Operation of the judgment system) Figure 10 is a flowchart showing an example of the operation of the determination system according to modified embodiment 2. The operation of the determination device 100b of the determination system 1b will be described with reference to Figure 10. (Steps S1-3) Multiple load data of subject SU from the center of gravity sway meter 50 are input to the input unit 101b of the judgment device 100b. For example, multiple load data of subject SU before subject SU is given a visual stimulus load are input to the input unit 101b, multiple load data of subject SU after subject SU is given a first visual stimulus load are input, multiple load data of subject SU after subject SU is given a second visual stimulus load are input, and multiple load data of subject SU after subject SU is given a third visual stimulus load are input.
[0093] (Step S2-3) The acquisition unit 102b of the determination device 100b acquires multiple load data of subject SU input to the input unit 101b. From the acquired multiple load data of subject SU, the acquisition unit 102b associates the multiple load data of subject SU before the visual stimulus load is applied to subject SU, the identification information of subject SU, and information indicating that the visual stimulus load has not yet been applied to subject SU, and stores them in the storage unit 110. The acquisition unit 102b associates the acquired load data of subject SU with the load data of subject SU after the first visual stimulus load has been applied to subject SU, the identification information of subject SU, and information indicating that the first visual stimulus load has been applied to subject SU, and stores this information in the storage unit 110. The acquisition unit 102b associates the acquired load data of subject SU with the load data of subject SU after the second visual stimulus load has been applied to subject SU, the identification information of subject SU, and information indicating that the second visual stimulus load has been applied to subject SU, and stores this information in the storage unit 110. The acquisition unit 102b stores in the storage unit 110, associating the multiple load data of the subject SU after the third visual stimulus load has been applied to the subject SU, the subject SU's identification information, and information indicating that the third visual stimulus load has been applied to the subject SU, from among the multiple load data of the subject SU that has been acquired.
[0094] (Step S3-3) The creation unit 104b of the determination device 100b acquires identification information of the subject SU, multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, and information indicating that the visual stimulus load has not yet been applied to the subject SU from the storage unit 110. Based on each of the acquired multiple load data of the subject SU before the visual stimulus load is applied to the subject SU, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions before the visual stimulus load is applied to the subject SU. The creation unit 104b obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the first visual stimulus load has been applied to the subject SU, and information indicating that the first visual stimulus load has been applied to the subject SU. Based on each of the multiple load data of the subject SU after the first visual stimulus load has been applied, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the first visual stimulus load has been applied to the subject SU.
[0095] The creation unit 104b obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the second visual stimulus load has been applied to the subject SU, and information indicating that the second visual stimulus load has been applied to the subject SU. Based on each of the multiple load data of the subject SU after the second visual stimulus load has been applied, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the second visual stimulus load has been applied to the subject SU. The creation unit 104b obtains from the storage unit 110 the identification information of the subject SU, multiple load data of the subject SU after the third visual stimulus load has been applied to the subject SU, and information indicating that the third visual stimulus load has been applied to the subject SU. Based on each of the multiple load data of the subject SU after the third visual stimulus load has been applied, the creation unit 104b calculates multiple center of gravity positions of the subject SU on the horizontal plane and creates scatter data of the center of gravity positions after the third visual stimulus load has been applied to the subject SU.
[0096] (Step S4-3) The determination unit 106b of the determination device 100b acquires from the creation unit 104b the following data: scatter data of the center of gravity position before subject SU is given a visual stimulus load, scatter data of the center of gravity position after subject SU is given a first visual stimulus load, scatter data of the center of gravity position after subject SU is given a second visual stimulus load, and scatter data of the center of gravity position after subject SU is given a third visual stimulus load. Based on the acquired scatter data of the center of gravity position before subject SU is given a visual stimulus load, the scatter data of the center of gravity position after subject SU is given a first visual stimulus load, the scatter data of the center of gravity position after subject SU is given a second visual stimulus load, and the scatter data of the center of gravity position after subject SU is given a third visual stimulus load, the determination unit 106b derives the area of the outer perimeter of the scatter data of the center of gravity position before subject SU is given a visual stimulus load, the area of the outer perimeter of the scatter data of the center of gravity position after subject SU is given a first visual stimulus load, the area of the outer perimeter of the scatter data of the center of gravity position after subject SU is given a second visual stimulus load, and the area of the outer perimeter of the scatter data of the center of gravity position after subject SU is given a third visual stimulus load.
[0097] (Step S5-3) The determination unit 106b of the determination device 100b determines, based on the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a first visual stimulus load, the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a second visual stimulus load, and the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a third visual stimulus load, that the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a first visual stimulus load is greater than the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a first visual stimulus load. It is determined whether at least one of the following conditions is met: the area of the perimeter increases by more than the first area threshold; the area of the perimeter of the scatter data of the centroid position after subject SU is given a second visual stimulus load increases by more than the second area threshold compared to the area of the perimeter of the scatter data of the centroid position before subject SU is given a second visual stimulus load; or the area of the perimeter of the scatter data of the centroid position after subject SU is given a third visual stimulus load increases by more than the third area threshold compared to the area of the perimeter of the scatter data of the centroid position before subject SU is given a third visual stimulus load.
[0098] (Step S6-3) The determination unit 106b of the determination device 100b determines that subject SU may have a dizziness disorder if it determines that at least one of the following conditions is met: the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a first visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a first visual stimulus load; the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a second visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a second visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a third visual stimulus load is greater than or equal to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a third before subject SU is given a first visual stimulus load.
[0099] (Step S7-3) The determination unit 106b of the determination device 100b determines that there is no possibility of dizziness disorder in subject SU if it determines that all of the following conditions are met: the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a first visual stimulus load does not increase by more than a first area threshold compared to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a second visual stimulus load does not increase by more than a second area threshold compared to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a second visual stimulus load; and the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a third visual stimulus load does not increase by more than a third area threshold compared to the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a third visual stimulus load. (Step S8-3) The output unit 108 of the determination device 100b obtains a determination result from the determination unit 106b regarding whether or not subject SU may have a dizziness disorder. The output unit 108 outputs the obtained determination result regarding the possibility of subject SU having a dizziness disorder.
[0100] In the modified example 2 of the above-described embodiment, an example of a third visual stimulus load was described in which a video is displayed in front of the subject's eyes in which one or more dots move in the positive or negative direction of the X-axis at a predetermined speed. However, the invention is not limited to this example. For example, the dots are not the only options; they may be ellipses or polygons. As an example of a third visual stimulus load, the visual stimulus load may be provided by displaying one or more dots that move randomly in front of the subject's eyes over time, or by displaying one or more dots that move in the positive or negative direction of the Z-axis at a predetermined speed in front of the subject's eyes over time, or by displaying one or more dots that move in the positive or negative direction of the Y-axis at a predetermined speed in front of the subject's eyes over time. As an example of a third visual stimulus load, the visual stimulus load may be provided by displaying one or more dots in front of the subject's eyes that move clockwise or counterclockwise around the X-axis at a predetermined speed over time. Alternatively, as an example of a third visual stimulus load, the visual stimulus load may be provided by displaying one or more dots in front of the subject's eyes that move toward the center of the projection area PA at a predetermined speed over time, or by displaying one or more dots in front of the subject's eyes that move toward the center of the projection area PA at a predetermined speed over time. As an example of a third visual stimulus load, the visual stimulus load may be provided by displaying one or more dots moving diagonally in front of the subject's eyes at a predetermined speed. Specifically, as an example of a third visual stimulus load, the visual stimulus load may be provided by displaying one or more dots moving in front of the subject's eyes at a predetermined speed from the positive side of the Y-axis to the positive side of the Z-axis at an angle greater than 0 degrees and less than 90 degrees. As an example of a third visual stimulus load, the visual stimulus load may be provided by displaying one or more dots moving in front of the subject's eyes at a predetermined speed from the negative side of the Y-axis to the negative side of the Z-axis at an angle greater than 0 degrees and less than 90 degrees. As an example of a third visual stimulus load, the visual stimulus load may be provided by displaying one or more dots in front of the subject's eyes that move at a predetermined speed from the negative side of the Y-axis to the positive side of the Z-axis in an angle greater than 0 degrees and less than 90 degrees. Furthermore, any of the aforementioned examples of third visual stimulus loads may be combined. In the modified embodiment 2, as an example, the determination unit 106b of the determination device 100b determines that subject SU may have a dizziness disorder when at least one of the following conditions is met: when the area of the outer perimeter of the scattered data when subject SU is given a first visual stimulus load increases by a first threshold or more compared to the area of the outer perimeter of the scattered data of the load data when subject SU is not given a visual stimulus load; when the area of the outer perimeter of the scattered data when subject SU is given a second visual stimulus load increases by a second threshold or more compared to the area of the scattered data of the load data when subject SU is not given a visual stimulus load; or when the area of the outer perimeter of the scattered data when subject SU is given a third visual stimulus load increases by a third threshold or more compared to the area of the scattered data of the load data when subject SU is not given a visual stimulus load. However, the invention is not limited to this example. For example, the conditions for determining that subject SU may have a dizziness disorder can be set as appropriate.
[0101] In the modified example 2 of the above-described embodiment, the determination device 100b describes a case in which the determination unit 106b derives the area of the outer perimeter of the scattered data of the center of gravity before the subject SU is given a visual stimulus load, the scattered data of the center of gravity after the subject SU is given a first visual stimulus load, the scattered data of the center of gravity after the subject SU is given a second visual stimulus load, and the scattered data of the center of gravity after the subject SU is given a third visual stimulus load, based on the scattered data of the center of gravity before the subject SU is given a visual stimulus load, the scattered data of the center of gravity after the subject SU is given a first visual stimulus load, the scattered data of the center of gravity after the subject SU is given a second visual stimulus load, and the scattered data of the center of gravity after the subject SU is given a third visual stimulus load. However, the invention is not limited to this example.
[0102] For example, the determination unit 106b may derive the density of the center of gravity of subject SU before subject SU is given a visual stimulus load, the density of the center of gravity of subject SU after subject SU is given a first visual stimulus load, the density of the center of gravity of subject SU after subject SU is given a second visual stimulus load, and the density of the center of gravity of subject SU after subject SU is given a third visual stimulus load, based on the scattered data of the center of gravity of subject SU before subject SU is given a visual stimulus load, the scattered data of the center of gravity of subject SU after subject SU is given a first visual stimulus load, the scattered data of the center of gravity of subject SU after subject SU is given a second visual stimulus load, and the scattered data of the center of gravity of subject SU after subject SU is given a third visual stimulus load.
[0103] For example, the determination unit 106b derives the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions before subject SU is given a visual stimulus load, the area of the outer perimeter of the scattered data, the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a first visual stimulus load, the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a second visual stimulus load, and the area of the outer perimeter of the scattered data, and the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a third visual stimulus load.
[0104] The determination unit 106b derives the density of centroid positions before subject SU is given a visual stimulus load by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions before subject SU is given a visual stimulus load by the area of the outer perimeter of the scattered data. The determination unit 106b derives the density of centroid positions after subject SU is given the first visual stimulus load by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given the first visual stimulus load by the area of the outer perimeter of the scattered data. The determination unit 106b derives the density of centroid positions after subject SU is given a second visual stimulus load by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a second visual stimulus load by the area of the outer perimeter of the scattered data. The determination unit 106b derives the density of centroid positions after subject SU is given a third visual stimulus load by dividing the number of centroid positions included in the region enclosed by the outer perimeter of the scattered data of centroid positions after subject SU is given a third visual stimulus load by the area of the outer perimeter of the scattered data.
[0105] The determination unit 106b determines, based on the density of the center of gravity positions before the subject SU is given a visual stimulus load and the density of the center of gravity positions after the subject SU is given a first visual stimulus load, whether the density of the center of gravity positions after the subject SU is given a first visual stimulus load has decreased by a first density threshold or more compared to the density of the center of gravity positions before the subject SU is given a visual stimulus load. The determination unit 106b determines, based on the density of the center of gravity positions before the subject SU is given a visual stimulus load and the density of the center of gravity positions after the subject SU is given a second visual stimulus load, whether the density of the center of gravity positions after the subject SU is given a second visual stimulus load has decreased by more than the second density threshold compared to the density of the center of gravity positions before the subject SU is given a second visual stimulus load.
[0106] The determination unit 106b determines that subject SU may have a dizziness disorder if it determines that at least one of the following conditions is met: the density of the center of gravity positions after subject SU is given a first visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a visual stimulus load is lower than the density of the center of gravity positions after subject SU is given a second visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a visual stimulus load is lower than the density of the center of gravity positions after subject SU is given a third visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a before subject SU is given a visual stimulus load is lower than the density of the center of gravity positions after subject SU is given a visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a visual stimulus load is lower than the density of the center of gravity positions before subject SU is given a visual stimulus load is lower than the density of the center of gravity positions after subject SU is given a visual stimulus load is lower than the density of the center of gravity positions before subject The determination unit 106b determines that subject SU does not have a dizziness disorder if it determines that all of the following conditions are met: the density of the center of gravity after subject SU is given a first visual stimulus load does not decrease by more than the first density threshold compared to the density of the center of gravity before subject SU is given a visual stimulus load; the density of the center of gravity after subject SU is given a second visual stimulus load does not decrease by more than the second density threshold compared to the density of the center of gravity before subject SU is given a visual stimulus load; and the density of the center of gravity after subject SU is given a third visual stimulus load does not decrease by more than the third density threshold compared to the density of the center of gravity before subject SU is given a visual stimulus load. The conditions for determining whether subject SU has a dizziness disorder can be set as appropriate.
[0107] In the modified embodiment 2 described above, the determination unit 106b may determine whether or not subject SU may have a dizziness disorder based on the area of the outer perimeter of the scattered data of the center of gravity position before subject SU is given a visual stimulus load and the area of the outer perimeter of the scattered data of the center of gravity position after subject SU is given a third visual stimulus load. For example, if the determination unit 106b determines that subject SU may have a dizziness disorder if the area of the outer perimeter of the scatter data of the center of gravity after subject SU is given a third visual stimulus load is greater than or equal to the third area threshold compared to the area of the outer perimeter of the scatter data of the center of gravity before subject SU is given a visual stimulus load. For example, the determination unit 106b determines that subject SU does not have a dizziness disorder if the area of the outer perimeter of the scatter data of the center of gravity after subject SU is given a third visual stimulus load does not increase by more than a third area threshold compared to the area of the outer perimeter of the scatter data of the center of gravity before subject SU is given a visual stimulus load.
[0108] In the modified example 2 of the above-described embodiment, the determination unit 106b may determine whether or not the condition is PPPD, which is included in dizziness disorders. For example, the first area threshold, the second area threshold, and the third area threshold may be set to determine whether or not the condition is PPPD or a dizziness disorder other than PPPD. Alternatively, by setting the first density threshold, the second density threshold, and the third density threshold to determine whether it is PPPD or a dizziness disorder other than PPPD, the determination unit 106b may determine whether or not it is PPPD, which is included in dizziness disorders.
[0109] According to the determination system 1b of the modified embodiment 2, the determination device 100b further includes a third visual stimulus load in the determination device 100a, which displays a dot pattern moving at a predetermined speed in front of the eyes of the subject SU. The acquisition unit 102b acquires the subject SU's third load data when the subject SU is given the third visual stimulus load. The creation unit 104b creates third scatter data of the subject's center of gravity coordinates based on the third load data acquired by the acquisition unit 102b. The determination unit 106b further determines the possibility of the subject having a dizziness disorder based on the third scatter data created by the creation unit 104b. By configuring it in this way, the determination device 100b can acquire multiple load data of subject SU when a third visual stimulus load is further applied, which displays a dot pattern moving at a predetermined speed in front of subject SU's eyes, and can create scatter data based on the acquired load data, thereby determining the possibility of subject SU having a dizziness disorder based on the created scatter data.
[0110] In the determination device 100b, the determination unit 106b determines the possibility of dizziness disorder in subject SU based on the area of the outer perimeter of the scatter data of the subject's centroid coordinates. By configuring it in this way, the determination device 100b can derive the area of the outer perimeter of the scatter data of the subject's centroid coordinates, and based on the area of the outer perimeter of the derived scatter data, it can determine the possibility of subject SU having a dizziness disorder.
[0111] In the determination device 100b, the determination unit 106b determines the possibility of dizziness disorder in subject SU based on the density of the scattered data of the subject's centroid coordinates. By configuring it in this way, the determination device 100b can derive the density of the scatter data of the subject's centroid coordinates, and based on the density of the derived scatter data, it can determine the possibility of subject SU having a dizziness disorder. In the determination device 100b, the determination unit 106b determines the possibility of persistent postural dizziness disorder in subject SU based on the scatter data of the subject's center of gravity coordinates. By configuring it in this way, the determination device 100b can determine the possibility of persistent postural dizziness disorder in subject SU.
[0112] Figure 11 shows an example of deriving the area of the outer perimeter of the scatter data of the center of gravity position in the determination system according to Modification 2 of the Embodiment. For each of the subjects—those with PPPD, those with unilateral vestibular dysfunction (unilateral), those with bilateral vestibular dysfunction (bilateral), those with central vertigo (central), healthy subjects, and those with psychogenic vertigo (psychogenic)—the ratio of the measured values with eyes open (before subject SU was given a visual stimulus load) to those with a visual stimulus load was calculated. The calculation results were analyzed using Ordinary one-way ANOVA. Specifically, multi-group comparisons were performed using the Tukey-Kramer method. (1) is the case when subject SU was given the first visual stimulus load. The p-value in this case was less than 0.0001. If a significance level of 0.05 is applied, the difference between the mean ratio of measurements with eyes open and with visual stimulus load is statistically significant for each of the subjects: subjects with PPPD, subjects with unilateral vestibular dysfunction, subjects with bilateral vestibular dysfunction, subjects with central vertigo, healthy subjects, and subjects with psychogenic vertigo. (2) is the case when subject SU was given a second visual stimulus load. The p-value in this case was 0.0166. If a significance level of 0.05 is applied, it can be seen that the difference between the mean ratio of measurements with eyes open and with visual stimulus load is statistically significant for each of the subjects: subjects with PPPD, subjects with unilateral vestibular dysfunction, subjects with bilateral vestibular dysfunction, subjects with central vertigo, healthy subjects, and subjects with psychogenic vertigo. (3) is the case when subject SU was given a third visual stimulus load. The p-value in this case was 0.0128. If a significance level of 0.05 is applied, it can be seen that the difference between the mean ratio of measurements with eyes open and with visual stimulus load is statistically significant for each of the subjects: subjects with PPPD, subjects with unilateral vestibular dysfunction, subjects with bilateral vestibular dysfunction, subjects with central vertigo, healthy subjects, and subjects with psychogenic vertigo. From the above, it can be seen that the area around the perimeter of the scattered data of the center of gravity can be used to assist in the diagnosis of dizziness such as PPPD in subjects SU.
[0113] Figure 12 shows an example of the derivation of the density of the center of gravity in the judgment system according to the modified example 2 of the embodiment. For each of the subjects, including subjects with PPPD, subjects with unilateral vestibular dysfunction (unilateral), subjects with bilateral vestibular dysfunction (bilateral), subjects with central vertigo (central), healthy subjects, and subjects with psychogenic vertigo (psychogenic), the ratio of measured values with eyes open to those with visual stimulation load was calculated. The calculation results were analyzed using one-way ANOVA. Specifically, multi-group comparisons were performed using the Tukey-Kramer method. (1) is the case when subject SU was given the first visual stimulus load. The p-value in this case was 0.0493. If a significance level of 0.05 is applied, the difference between the mean ratio of measurements with eyes open and with visual stimulus load is statistically significant for each of the subjects: subjects with PPPD, subjects with unilateral vestibular dysfunction, subjects with bilateral vestibular dysfunction, subjects with central vertigo, healthy subjects, and subjects with psychogenic vertigo. (2) is the case when subject SU was given a second visual stimulus load. The p-value in this case was 0.04894. If a significance level of 0.05 is applied, it can be seen that the difference between the mean ratio of measurements with eyes open and with visual stimulus load is statistically significant for each of the subjects: subjects with PPPD, subjects with unilateral vestibular dysfunction, subjects with bilateral vestibular dysfunction, subjects with central vertigo, healthy subjects, and subjects with psychogenic vertigo. (3) is the case when subject SU was given a third visual stimulus load. The p-value in this case was 0.04647. If a significance level of 0.05 is applied, it can be seen that the difference between the mean ratio of measurements with eyes open and with visual stimulus load is statistically significant for each of the subjects: subjects with PPPD, subjects with unilateral vestibular dysfunction, subjects with bilateral vestibular dysfunction, subjects with central vertigo, healthy subjects, and subjects with psychogenic vertigo. From the above, it can be seen that the density of the center of gravity can be used to assist in the diagnosis of dizziness such as PPPD in subjects SU.
[0114] Next, for SU, a subject with PPPD, scatter plots of the center of gravity were created before and after the introduction of an SSRI (Selective Serotonin Reuptake Inhibitor), both with and without visual stimulation. The area of the outer perimeter of the scatter plots, the movement speed of the center of gravity, the density of the center of gravity, the left-right center of the center of gravity, and the front-back center of the center of gravity were then derived. Figure 13A shows an example of the derivation of scatter data for the centroid position in the determination system according to a modified example 2 of the embodiment. (1) is the case before SSRIs were introduced and no visual stimulus load was applied. (2) is the case before SSRIs were introduced and a visual stimulus load was applied. Based on (1) and (2), it can be seen that when subjects SU were given a visual stimulus load, the area of the outer edge of the scatter data for the centroid position was wider compared to when subjects SU were not given a visual stimulus load. (3) is the case where no visual stimulus load is applied after the introduction of an SSRI. (4) is the case where a visual stimulus load is applied after the introduction of an SSRI. According to (3) and (4), there is little change in the area of the outer perimeter of the scatter data for the centroid position between the case where the subject SU is given a visual stimulus load and the case where the subject SU is not given a visual stimulus load. According to (1) to (4), when SSRIs are introduced and treatment is performed, the area around the perimeter of the centroid position scatter data becomes smaller compared to when SSRIs are not introduced, indicating that the symptoms have improved. Figure 13B shows an example of the derivation of scatter data for the centroid position in the determination system according to a modified example 2 of the embodiment. (1) shows the results obtained by deriving the area of the perimeter of the scatter data of the center of gravity, the movement speed of the center of gravity, the density of the center of gravity, the left-right center of the center of gravity, and the front-back center of the center of gravity before the introduction of SSRIs, with and without visual stimulus loading. According to (1), it can be seen that by applying visual stimulus loading, the area of the perimeter of the scatter data of the center of gravity, the movement speed of the center of gravity, the density of the center of gravity, the left-right center of the center of gravity, and the front-back center of the center of gravity increase compared to the case without visual stimulus loading. (2) shows the results obtained after introducing an SSRI, comparing the area of the perimeter of the scatter data of the center of gravity, the movement speed of the center of gravity, the density of the center of gravity, the left-right center of the center of gravity, and the front-back center of the center of gravity, both with and without visual stimulation. According to (2), the changes in the area of the perimeter of the scatter data of the center of gravity, the movement speed of the center of gravity, the density of the center of gravity, the left-right center of the center of gravity, and the front-back center of the center of gravity are smaller with and without visual stimulation compared to before the introduction of the SSRI. According to (1) and (2), when SSRIs are introduced and treatment is performed, the changes in the area of the outer perimeter of the scatter data of the center of gravity, the movement speed of the center of gravity, the density of the center of gravity, the left-right center of the center of gravity, and the front-back center of the center of gravity are smaller compared to when SSRIs are not introduced, indicating that the symptoms are improving.
[0115] Although embodiments of the present invention have been described above, these embodiments are presented as examples and are not intended to limit the scope of the invention. These embodiments can be implemented in various other forms, and various omissions, substitutions, modifications, and combinations can be made without departing from the spirit of the invention. These embodiments and their variations are included in the scope and spirit of the invention, as well as in the claims and their equivalents. Furthermore, the aforementioned determination devices 100, 100a, and 100b each have an internal computer. The processes of each of the aforementioned devices are stored in program form on a computer-readable recording medium, and the above processes are performed by reading and executing this program on the computer. Here, a computer-readable recording medium refers to a magnetic disk, magneto-optical disk, CD-ROM, DVD-ROM, semiconductor memory, etc. Alternatively, this computer program may be distributed to a computer via a communication line, and the computer that receives this distribution may execute the program. Furthermore, the above program may be intended to implement some of the functions described above. Furthermore, the aforementioned functions may be implemented in combination with programs already recorded in the computer system, such as so-called differential files (differential programs). [Explanation of Symbols]
[0116] 1, 1a, 1b… Judgment system, 50… Center of gravity sway meter, 70… Projection unit, 100, 100a, 100b… Judgment device, 101, 101a, 101b… Input unit, 102, 102a, 102b… Acquisition unit, 104, 104a, 104b… Creation unit, 106, 106a, 106b… Judgment unit, 108… Output unit, 110… Memory unit
Claims
1. An acquisition unit that acquires load data of the subject when a visual stimulus load is applied to the subject, A creation unit creates scatter data of the subject's center of gravity coordinates based on the load data acquired by the acquisition unit, A determination unit determines the possibility of the subject having a dizziness disorder based on the scatter data of the centroid coordinates created by the creation unit. Equipped with, The aforementioned visual stimulus load includes a first visual stimulus load that displays a checkerboard pattern that reverses at predetermined intervals in front of the subject's eyes, The acquisition unit acquires the subject's first load data when the subject is given the first visual stimulus load. The creation unit creates first scatter data of the subject's center of gravity coordinates based on the first load data acquired by the acquisition unit. The determination unit determines the possibility of a dizziness disorder in the subject based on the first scattered data created by the creation unit and the scattered data of the center of gravity position before the subject is given the visual stimulus load, deriving the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load and the area of the outer perimeter of the first scattered data, and determining the possibility of a dizziness disorder in the subject based on the area of the outer perimeter of the first scattered data of the center of gravity coordinates and the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load.
2. The visual stimulus load further includes a second visual stimulus load that displays a linear pattern moving in front of the subject's eyes at a predetermined speed, The acquisition unit acquires the subject's second load data when the subject is given the second visual stimulus load. The creation unit creates second scatter data of the subject's center of gravity coordinates based on the second load data acquired by the acquisition unit. The determination unit, based on the second scattered data created by the creation unit and the scattered data of the center of gravity position before the subject is given the visual stimulus load, derives the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load and the area of the outer perimeter of the second scattered data, and further determines the possibility of the subject having a dizziness disorder based on the area of the outer perimeter of the second scattered data of the center of gravity coordinates and the area of the outer perimeter of the scattered data of the center of gravity position before the subject is given the visual stimulus load, as described in claim 1.
3. The aforementioned visual stimulus load further includes a third visual stimulus load that displays a dot pattern moving at a predetermined speed in front of the subject's eyes, The acquisition unit acquires the subject's third load data when the subject is given a third visual stimulus load. The creation unit creates third scatter data of the subject's center of gravity coordinates based on the third load data acquired by the acquisition unit. The determination unit, based on the third scattered data created by the creation unit and the scattered data of the center of gravity position before the visual stimulus load was applied to the subject, derives the area of the outer perimeter of the scattered data of the center of gravity position before the visual stimulus load was applied to the subject and the area of the outer perimeter of the third scattered data, and further determines the possibility of the subject having a dizziness disorder based on the area of the outer perimeter of the third scattered data of the center of gravity coordinates and the area of the outer perimeter of the scattered data of the center of gravity position before the visual stimulus load was applied to the subject, as described in claim 1 or claim 2.
4. The determination device according to claim 1, wherein the determination unit determines the possibility of a subject having a dizziness disorder based on the density of the scatter data of the subject's centroid coordinates.
5. The determination device according to claim 1, wherein the determination unit determines the possibility of the subject having persistent postural dizziness disorder based on the scatter data of the subject's center of gravity coordinates.
6. A step of acquiring load data of the subject when a visual stimulus load is applied to the subject, A step of creating scatter data of the center of gravity coordinates of the subject based on the load data obtained in the aforementioned acquisition step, A step of determining the possibility of the subject having a dizziness disorder based on the scatter data of the centroid coordinates created in the above step, It has, The aforementioned visual stimulus load includes a first visual stimulus load that displays a checkerboard pattern that reverses at predetermined intervals in front of the subject's eyes, In the acquisition step, when the subject is given the first visual stimulus load, the subject's first load data is acquired. In the creation step, first scatter data of the subject's center of gravity coordinates is created based on the first load data obtained in the acquisition step. A computer-based determination method, comprising the determination step, which involves deriving the area of the outer perimeter of the scatter data of the center of gravity before the visual stimulus load was applied to the subject and the area of the outer perimeter of the first scatter data based on the first scatter data created in the creation step and the scatter data of the center of gravity position before the visual stimulus load was applied to the subject, and determining the possibility of the subject having a dizziness disorder based on the area of the outer perimeter of the first scatter data of the center of gravity coordinates and the area of the outer perimeter of the scatter data of the center of gravity position before the visual stimulus load was applied to the subject.
7. On the computer, A step of acquiring load data of the subject when a visual stimulus load is applied to the subject, A step of creating scatter data of the center of gravity coordinates of the subject based on the load data obtained in the aforementioned acquisition step, A step of determining the possibility of the subject having a dizziness disorder based on the scatter data of the centroid coordinates created in the above step, Make it run, The aforementioned visual stimulus load includes a first visual stimulus load that displays a checkerboard pattern that reverses at predetermined intervals in front of the subject's eyes, In the acquisition step, when the subject is given the first visual stimulus load, the subject's first load data is acquired. In the creation step, first scatter data of the subject's center of gravity coordinates is created based on the first load data obtained in the acquisition step. In the determination step, the program derives the area of the outer perimeter of the scatter data of the center of gravity before the visual stimulus load is applied to the subject and the area of the outer perimeter of the first scatter data, based on the first scatter data created in the creation step and the scatter data of the center of gravity position before the visual stimulus load is applied to the subject, and determines the possibility of the subject having a dizziness disorder based on the area of the outer perimeter of the first scatter data of the center of gravity coordinates and the area of the outer perimeter of the scatter data of the center of gravity position before the visual stimulus load is applied to the subject.