Oral components
An oral composition with gellan gum, locust bean gum, and/or xanthan gum increases myoelectric potential, addressing the need for muscle strengthening around the mouth to prevent oral frailty in the elderly.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- SUNSTAR INC
- Filing Date
- 2021-12-20
- Publication Date
- 2026-06-08
AI Technical Summary
There is a need for oral compositions that can effectively strengthen the muscles around the mouth to counteract the decline in physical and mental functions associated with aging, particularly for preventing oral frailty in the elderly.
An oral composition containing gellan gum, locust bean gum, and/or xanthan gum, with specific mass percentages, is used to increase myoelectric potential and improve muscle strength by rinsing the oral cavity.
The composition enhances muscle strength around the oral cavity, effectively preventing oral frailty by stimulating muscles through increased myoelectric potential, suitable for oral training and perioral muscle strengthening.
Smart Images

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Abstract
Description
Technical Field
[0001] The present disclosure relates to an oral composition and its uses, etc.
Background Art
[0002] Conventionally, oral compositions containing gelling agents such as gellan gum, xanthan gum, and locust bean gum have been known (Patent Document 1).
[0003] Moreover, as the population ages, the physical and mental functions gradually decline with aging, and while becoming frail, the degree of independence decreases and eventually leads to a state of needing care. Therefore, it is considered important to raise the preventive awareness among all citizens.
Prior Art Documents
Patent Documents
[0004]
Patent Document 1
Summary of the Invention
Problems to be Solved by the Invention
[0005] An object of the present disclosure is to provide an oral composition for oral training (for example, for strengthening the muscles around the mouth).
Means for Solving the Problems
[0006] The inventors of the present invention have found that by using a composition in which gellan gum and locust bean gum and / or xanthan gum are used in combination and rinsing the oral cavity, the generation of myoelectric potential increases, and further improvements have been made.
[0007] The present disclosure includes, for example, the subject matter described in the following items. Item 1. A composition for oral training containing gellan gum, and locust bean gum and / or xanthan gum. The composition contains gellan gum in an amount of 0.075% by mass or more. A composition wherein the total amount of locust bean gum and / or xanthan gum in the composition is 0.225% by mass or more. Section 2. In the aforementioned composition, gellan gum, and The composition according to item 1, wherein the total amount of locust bean gum and / or xanthan gum is 1.0% by mass or less. Section 3. A gel-like composition as described in item 1 or 2. Section 4. A composition according to any one of items 1 to 3, for the prevention of oral frailty in the elderly. Section 5. A composition according to any one of items 1 to 4, wherein the water content is 70% by mass or more. Section 6. The composition according to any one of items 1 to 5, wherein the composition is filled into a cylindrical bottle with a diameter of 4 cm to a height of 5 cm, left to stand at 5°C for 17 hours, and the pressing pressure measured using a rheometer with a circular pressure-sensitive axis of 3 cm in diameter at a sample stage movement speed of 10 mm / second is 1 to 40 N. Section 7. The composition according to any one of items 1 to 6, wherein the amount of water released after being left at 40°C for 3 days (g / 20g) is less than 1.0g / 20g. Section 8. Gellan gum, and An oral composition containing locust bean gum and / or xanthan gum, The composition contains gellan gum in an amount of 0.075% by mass or more. Using the above composition, the total amount of locust bean gum and / or xanthan gum is 0.225% by mass or more. Including cleaning the inside of the mouth, Oral training methods. [Effects of the Invention]
[0008] An oral composition is provided for oral training (for example, for strengthening the muscles around the oral cavity). [Brief explanation of the drawing]
[0009] [Figure 1] The results of evaluating the effect of calcium lactate content on physical properties are shown. [Modes for carrying out the invention]
[0010] The embodiments included in this disclosure will be described in further detail below. The compositions included in this disclosure are oral compositions containing gellan gum, locust bean gum, and / or xanthan gum. In this specification, such oral compositions may be referred to as "Oral Compositions of the Disclosure."
[0011] The gellan gum used in this disclosure is a fermentation polysaccharide produced by Sphingomonas elodea. In the oral compositions of this disclosure, the gellan gum content is preferably 0.075% by mass or more. The upper or lower limit of this numerical range can be, for example, approximately 0.08, 0.09, 0.1, 0.11, 0.12, 0.13, 0.14, 0.15, 0.16, 0.17, 0.18, 0.19, 0.2, 0.21, 0.22, 0.23, 0.24, 0.25, 0.3, 0.35, 0.4, or 0.5% by mass. More specifically, it may be, for example, approximately 0.08 to 0.4% by mass.
[0012] The roasted bean gum used in this disclosure is a polysaccharide obtained from the seeds of the evergreen plant carob tree (scientific name: Celatonia siliqua). When the oral composition of the present disclosure contains locust bean gum, the content of locust bean gum in the oral composition of the present disclosure can be, for example, about 0.05 to 0.5% by mass. The upper or lower limit of this numerical range can be, for example, about 0.06, 0.07, 0.08, 0.09, 0.1, 0.11, 0.12, 0.13, 0.14, 0.15, 0.16, 0.17, 0.18, 0.19, 0.2, 0.25, 0.3, 0.35, or 0.4% by mass. More specifically, for example, it may be about 0.06 to 0.25% by mass.
[0013] The xanthan gum used in the present disclosure is a fermented polysaccharide produced by Xanthomonas campestris. When the oral composition of the present disclosure contains xanthan gum, the content of xanthan gum in the oral composition of the present disclosure can be, for example, about 0.05 to 0.5% by mass. The upper or lower limit of this numerical range can be, for example, about 0.06, 0.07, 0.08, 0.09, 0.1, 0.11, 0.12, 0.13, 0.14, 0.15, 0.16, 0.17, 0.18, 0.19, 0.2, 0.25, 0.3, 0.35, or 0.4% by mass. More specifically, for example, it may be about 0.06 to 0.25% by mass.
[0014] When the oral composition of the present disclosure contains locust bean gum and xanthan gum, the content mass ratio of locust bean gum to xanthan gum in the oral composition of the present disclosure can be, for example, about 0.2 to 6 parts by mass of xanthan gum with respect to 1 part by mass of locust bean gum. The upper or lower limit of this numerical range can be, for example, about 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2, 3, 4, or 5. More specifically, for example, it may be about 0.3 to 5 parts by mass.
[0015] In the oral compositions of this disclosure, the total amount of locust bean gum and xanthan gum is preferably, for example, 0.225% by mass or more. The upper or lower limit of this numerical range can be, for example, approximately 0.23, 0.24, 0.25, 0.26, 0.27, 0.28, 0.29, 0.3, 0.31, 0.32, 0.33, 0.34, 0.35, 0.4, 0.45, 0.5, 0.55, or 0.6% by mass. More specifically, it may be, for example, approximately 0.23 to 0.6% by mass.
[0016] In the oral compositions of this disclosure, the total amount of gellan gum, locust bean gum, and xanthan gum can be, for example, about 0.3 to 1.5% by mass. The upper or lower limit of this numerical range can be, for example, about 0.31, 0.32, 0.33, 0.34, 0.35, 0.36, 0.37, 0.38, 0.39, 0.4, 0.41, 0.42, 0.43, 0.44, 0.45, 0.46, 0.47, 0.48, 0.49, 0.5, 0.51, 0.52, 0.53, 0.54, 0.55, 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, or 1.4% by mass. More specifically, it may be, for example, about 0.31 to 0.9% by mass.
[0017] In the oral compositions of this disclosure, the mass ratio of gellan gum to roasted bean gum and / or xanthan gum can be, for example, 0.6 to 8 parts by mass of roasted bean gum and / or xanthan gum for every 1 part by mass of gellan gum. The upper or lower limits of this numerical range can be, for example, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3, 3.1, 3.2, 3.3, 3.4, 3.5, 4, 5, 6, or 7 parts by mass. More specifically, for example, it may be about 0.7 to 7 parts by mass.
[0018] In the oral compositions of this disclosure, the water content is preferably, for example, 50% by mass or more. The upper or lower limit of this numerical range can be, for example, approximately 55, 60, 65, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, or 95% by mass. More specifically, it may be, for example, approximately 71 to 95% by mass.
[0019] The oral compositions of this disclosure may contain, in addition to the components described above, other known components that can be included in oral compositions. Examples of known components include water-soluble polyvalent metal salts, wetting agents, dispersants, surfactants, active ingredients, flavoring agents, cleaning aids, and the like. These can be used individually or in combination of two or more.
[0020] Examples of water-soluble polyvalent metal salts include water-soluble polyvalent metal salts of organic acids such as calcium lactate, magnesium lactate, calcium gluconate, and calcium glycerophosphate; and water-soluble polyvalent metal salts of inorganic acids such as magnesium chloride, calcium chloride, and magnesium sulfate. Among these, water-soluble polyvalent metal salts of organic acids are preferred, and calcium lactate is particularly preferred. In the oral compositions of this disclosure, the content of water-soluble polyvalent metal salts can be, for example, about 0.01 to 2% by mass. The upper or lower limit of this numerical range can be, for example, about 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.11, 0.12, 0.13, 0.14, 0.15, 0.16, 0.17, 0.18, 0.19, 0.2, 0.21, 0.22, 0.23, 0.24, 0.25, 0.26, 0.27, 0.28, 0.29, 0.3, 0.35, 0.4, 0.45, 0.5, 1, or 1.5% by mass. More specifically, it may be, for example, about 0.03 to 1.5% by mass. In the oral compositions of this disclosure, the mass ratio of gellan gum to water-soluble polyvalent metal salt can be, for example, about 0.3 to 6 parts by mass of water-soluble polyvalent metal salt per 1 part by mass of gellan gum. The upper or lower limit of this numerical range can be, for example, about 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2, 3, 4, or 5. More specifically, for example, about 0.4 to 5 parts by mass is preferred, 0.5 to 1.5 parts by mass is more preferred, and 1.2 parts by mass is particularly preferred.
[0021] Examples of wetting agents include ethanol, glycerin, sorbitol, ethylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylitol, maltitol, lactitol, erythritol, palatinose, and palatinose. Among these, glycerin is preferred. In the oral compositions of this disclosure, the content of the wetting agent can be, for example, about 5 to 30% by mass. The upper or lower limit of this numerical range can be, for example, about 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, or 29% by mass. More specifically, it may be, for example, about 6 to 29% by mass.
[0022] Examples of dispersants include cellulose derivatives such as sodium carboxymethylcellulose, methylcellulose, and hydroxyethylcellulose; and synthetic water-soluble polymers such as sodium polyacrylate, polyoxyethylene polyoxypropylene copolymer, polyvinyl alcohol, carboxyvinyl polymer, and polyvinylpyrrolidone.
[0023] Examples of surfactants include anionic surfactants such as sodium lauryl sulfate, sodium myristyl sulfate, N-lauroyl sarcosinate, lauroyl methyl taurine, and acyl amino acid salts; and nonionic surfactants such as sucrose fatty acid esters, decaglyceryl laurate, myristate diethanolamide, and polyoxyethylene hydrogenated castor oil.
[0024] Examples of active ingredients include fluorine compounds such as sodium fluoride, sodium monofluorophosphate, and stannous fluoride; enzymes such as dextranase, mutanase, protease, and lysozyme; tranexamic acid, ε-aminocaproic acid, aluminum chlorohydroxyallantoin, allantoin, dihydrocholesterol, glycyrrhizic acid derivatives, bisabolol, isopropylmethylphenol, glycerophosphate, chlorophyll, copper gluconate, sodium chloride, water-soluble inorganic phosphate compounds, chlorhexidine salts, triclosan, cetylpyridinium chloride, benzalkonium chloride, and benzethonium chloride; vitamins such as dl-α-tocopherol acetate, pyridoxine acetate, ascorbic acid or its salts; and plant extracts such as thyme and scutellaria baicalensis.
[0025] Examples of flavoring agents include sodium saccharin, potassium acesulfame, stevioside, glycyrrhizin and its salts, aspartylphenylalanine methyl ester, menthol, anethole, carvone, eugenol, limonene, peppermint oil, spearmint oil, wintergreen, methyl salicylate, cineole, thymol, clove oil, eucalyptus oil, rosemary oil, sage oil, lemon oil, orange oil, ocimen oil, citronellol, and methyl eugenol.
[0026] Examples of cleaning aids include precipitated silica, zirconosilicate, aluminosilicate, calcium phosphate, calcium carbonate, aluminum hydroxide, and aluminum oxide.
[0027] The oral compositions of this disclosure can be prepared by conventional methods by combining the above-mentioned components.
[0028] The oral composition of this disclosure preferably has a pH of about 4.5 to 7.5, and more preferably about 5.5 to 7.
[0029] The oral composition of this disclosure is preferably such that the pressure applied when the composition is filled into a cylindrical bottle with a diameter of 4 cm to a height of 5 cm, left to stand at 5°C for 17 hours, and then measured using a rheometer with a circular pressure-sensitive axis of 3 cm in diameter at a sample stage movement speed of 10 mm / second is between 1 and 40 N. For example, a SUN RHEO METER CR-500DX (manufactured by Sun Science Co., Ltd.) can be used as a rheometer. As for the jig used for measurement, examples include a pressure-sensitive shaft for compression elasticity, No. 1, Φ3cm, circular. The upper or lower limit of the numerical range for the pressing force can be, for example, approximately 1, 2, 3, 4, 5, 5.5, 6, 6.5, 7, 7.5, 8, 8.5, 9, 9.5, 10, 10.5, 11, 11.5, 12, 12.5, 13, 13.5, 14, 14.5, 15, 15.5, 16, 16.5, 17, 17.5, 18, 18.5, 19, 19.5, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, or 39 N. More specifically, it may be approximately 3 to 20 N.
[0030] The oral composition disclosed herein preferably has a syneresis rate (g / 20g) of less than 1.0g / 20g after being left at 40°C for 3 days, as measured under the following conditions. Measurement conditions: 20g of a sample cut into 1cm squares is placed in a 50ml conical tube (Falcon), left at 40°C for 3 days, then passed through a stainless steel sieve (Tokyo Screen Co., Ltd.) with a mesh size of 750μm and a wire diameter of 450μm, and the weight of the liquid that falls into the receiving tray is measured. If syneresis has already occurred in the sample used for measurement, the above measurement is performed using a sample that has been passed through a stainless steel sieve (Tokyo Screen Co., Ltd.) with a mesh size of 750μm and a wire diameter of 450μm (a sample from which syneresis that occurred before being left at 40°C for 3 days has been removed). The upper or lower limit of the numerical range for the amount of syneresis (g / 20g) after being left at 40°C for 3 days can be, for example, approximately 0, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, or 0.9 g / 20g. More specifically, it may be approximately 0 to 0.9 g / 20g. In this specification, "syneresis" means the exudation of water.
[0031] The oral compositions of this disclosure preferably have a syneresis rate (%) of 25% or less, as measured under the following conditions. Measurement conditions: The sample (e.g., oral composition filled in a container) is placed through a stainless steel sieve (manufactured by Tokyo Screen Co., Ltd.) with a mesh opening of 750 μm and a wire diameter of 450 μm. The weight of the water that falls into the receiving tray is measured, and the amount of water released relative to the weight of the sample used for measurement is calculated as the water release rate (%). The upper or lower limit of the numerical range for the water separation rate (%) measured under the above conditions can be, for example, approximately 0.5, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, or 24%. More specifically, it may be approximately 0.5 to 24%.
[0032] The oral composition of this disclosure is preferably in the form of a solution, suspension, gel, etc., for example. Among these, a gel is preferred. In this specification, "gel" means a semi-solid state containing a large amount of water.
[0033] The oral composition of this disclosure is preferably used by circulating it in the oral cavity, moving it back and forth between the teeth, swishing it around, and then spitting it out of the oral cavity. For example, it is preferable to use the oral composition by circulating it in the oral cavity, moving it back and forth between the teeth, swishing it around, etc., until its viscosity decreases, and then spitting it out of the oral cavity. For this reason, the oral composition of this disclosure is preferably used, for example, as a mouthwash.
[0034] As shown in the examples described later, washing the oral cavity with the oral composition of this disclosure increases the myoelectric potential (action potential generated when muscle cells (also called muscle fibers) contract) in the muscles around the oral cavity. When washing the oral cavity with the oral composition of this disclosure, muscles inside and outside the oral cavity are used, and this stimulates the muscles inside and outside the oral cavity, which is thought to help improve or maintain muscle strength. For this reason, the oral composition of this disclosure can be suitably used, for example, for oral training, perioral muscle training, perioral muscle strengthening, and lip closure strength strengthening. Furthermore, the oral composition of this disclosure can be suitably used, for example, for preventing oral frailty in the elderly. Elderly individuals include, for example, people aged 60 and over. "Oral frailty" is a concept that sounds the alarm about the negative chain reaction that can occur if minor declines in oral health are left unattended or inappropriate, leading to a decline in oral function, impaired eating function, and even a decline in physical and mental function. In this specification, it means "a decline in oral health literacy, minor oral problems, a decline in oral function, or impaired eating function" (Oral Frailty Management Manual for Dental Clinics, 2019 Edition). More specifically, a decline in oral health literacy includes, for example, insufficient interest in oral health. Minor oral problems include, for example, slurred speech, food spillage, an increase in foods that cannot be chewed, and choking. A decline in oral function includes, for example, poor oral hygiene or dryness, decreased biting force, decreased function of the lips or tongue, and decreased masticatory or swallowing function. Examples of impairments in eating function include chewing disorders and swallowing disorders. For this reason, the oral composition of this disclosure is suitably used, for example, for preventing age-related decline in articulation, preventing food spillage due to aging, preventing choking due to aging, preventing oral uncleanliness or dryness due to aging, preventing age-related decline in bite strength, preventing age-related decline in lip or tongue function, preventing age-related decline in chewing or swallowing function, preventing age-related chewing disorders, and preventing age-related swallowing disorders. Furthermore, examples of elderly individuals for whom the oral composition of this disclosure is suitable include elderly individuals with age-related decline in articulation, elderly individuals who spill food due to aging, elderly individuals who choke due to aging, elderly individuals with oral uncleanliness or dryness due to aging, elderly individuals with age-related decline in bite strength, elderly individuals with age-related decline in lip or tongue function, and elderly individuals with age-related decline in chewing or swallowing function.
[0035] The oral composition of this disclosure can be obtained by using gellan gum, which has a jelly-like disintegration property, and locust bean gum and / or xanthan gum, which have an elastic and chewy texture, in the above-mentioned amounts, in combination to obtain a composition suitable for oral training (e.g., strengthening of muscles around the mouth). Furthermore, the oral composition of this disclosure can be made by using gellan gum, which has jelly-like disintegration properties, and locust bean gum and / or xanthan gum, which have an elastic and chewy texture, in the above-mentioned amounts in combination to obtain a composition with less syneresis.
[0036] This disclosure also includes an oral training method, which involves cleaning the oral cavity using the oral composition described above.
[0037] Examples of oral training include training and strengthening of the muscles around the mouth and lips, and strengthening of lip closure. In this specification, "to wash the inside of the mouth" means to wash and rinse the inside of the mouth. This is also called mouthwash. More specifically, examples include circulating the contents of the mouth, moving the contents back and forth between the teeth, swishing, etc., and then spitting out. The washing time can be, for example, until the viscosity of the oral composition decreases. For example, it can be about 5 to 30 seconds. The amount of oral composition used for cleaning can be, for example, about 5 to 15 mL. The washing may be performed, for example, once a day, or two or three times a day.
[0038] In this specification, the term "comprising" includes both "consisting essentially of" and "consisting of." Furthermore, this disclosure encompasses all combinations of the constituent elements described herein.
[0039] Furthermore, the various characteristics (properties, structure, function, etc.) described in each embodiment of this disclosure above may be combined in any way to identify the subject matter covered by this disclosure. In other words, this disclosure covers all subject matter consisting of any combination of the combinable characteristics described herein. [Examples]
[0040] The contents of this disclosure will be specifically explained using the following examples. However, this disclosure is not limited to these examples. Unless otherwise specified below, the experiments were conducted under atmospheric pressure and room temperature conditions. Unless otherwise specified, "%" means "mass%". Also, unless otherwise specified, the composition values of each component listed in each table are also in "mass%".
[0041] [Preparation of composition] A gel-type mouthwash composition was prepared according to the formulation shown in Table 1 below. More specifically, the binders ((A), (B), and (C)) were dissolved by adding water and heating to approximately 80°C while dispersing and stirring. The other components were then added and stirred until homogeneous, and then cooled and solidified to obtain the composition.
[0042] [Evaluation of water release] 20g of a gel-type mouthwash composition, cut into 1cm squares, was placed in a 50ml conical tube (manufactured by Falcon). After being left at 40°C for 3 days, the mixture was passed through a stainless steel sieve (manufactured by Tokyo Screen Co., Ltd.) with a mesh size of 750μm and a wire diameter of 450μm, and the weight of the liquid that fell into the tray was measured. The amount of water released after 3 days at 40°C (g / 20g) and the evaluation results based on the following evaluation criteria are shown in Table 1. (Evaluation Criteria) 0g or more but less than 1g: ○ 1g or more but less than 2g: △ 2g or more: ×
[0043] [Eyzoelectric Potential Measurement] A dry, two-pole miniature electromyograph sensor (manufactured by Logical Product Co., Ltd.) was attached to the upper right portion of the lip, along the direction of the muscle fibers of the orbicularis oris muscle. The prepared gel-like mouthwash composition was placed in the mouth, and the electromyographic potential generated during 10-second rinsing was measured at a sampling frequency of 1 kHz. The RMS (effective value) of the generated electromyographic potential was integrald over the area. The relative value was calculated with the area integral value when rinsing with water set to 1. The average values of the results from the two subjects, and the evaluation results based on the following evaluation criteria, are shown in Table 1. (Evaluation Criteria) 1.2 or higher: ○ Less than 1 to 1.2: △ Less than 1: ×
[0044] [User experience evaluation] Five panelists each used 9 mL of the prepared gel-type mouthwash composition to rinse their mouths, and judged whether they felt they were using their muscles during rinsing according to the following criteria. The average values of the evaluation results from the five panelists, as well as the evaluation results based on the following criteria, are shown in Table 1. (Evaluation Criteria) 1: I think so 2: I somewhat agree. 3: I can't say either way. 4: I don't really think so. 5: I don't think so. (Evaluation criteria based on the average of 5 people) Less than 3.0: ○ 3.0 or higher but less than 3.5: △ 3.5 or higher: ×
[0045] [Table 1]
[0046] [Hardness rating] The gel-like mouthwash composition, immediately after preparation, was filled into a cylindrical bottle with a diameter of 4 cm to a height of 5 cm, left to stand at 5°C for 17 hours, and its hardness was evaluated as described below. Measuring device: SUN RHEO METER CR-500DX (manufactured by Sun Science Co., Ltd.) Measurement conditions: Pressure-sensitive shaft for compression elasticity, No. 1, Φ3cm, circular. Sample stage movement speed: 10 mm / second Hardness: The pressure (N) required when the pressure-sensitive shaft penetrates the gel-like mouthwash composition and first breaks.
[0047] The pressing forces for Examples 1 to 4 were 6.87 N, 7.96 N, 8.27 N, and 15.08 N, respectively.
[0048] Gel-type mouthwash compositions were prepared in the same manner as in Example 1 of Table 1, except that the amount of calcium lactate was changed to 0.06, 0.18, 0.24, or 0.3%. For each composition, the pressing pressure (N) was measured using the method described above, and in the hardness evaluation, the distance at which the pressure-sensitive axis penetrated the gel and first broke (penetration distance (mm)) was measured to evaluate elasticity. The results are shown in Figure 1.
[0049] As shown in Figure 1, it was found that when 0.1% gellan gum was mixed with 0.12% calcium lactate, the resulting material had low hardness while providing the greatest elasticity.
Claims
1. Gellan gum, locust bean gum and xanthan gum, and At least one water-soluble polyvalent metal salt selected from the group consisting of calcium lactate, calcium gluconate, and calcium glycerophosphate. A composition for oral training containing, The composition contains gellan gum in an amount of 0.075% by mass or more. In the above composition, the total amount of locust bean gum and xanthan gum is 0.225% by mass or more. The composition wherein the content of a water-soluble polyvalent metal salt is 0.3 to 2 parts by mass per 1 part by mass of gellan gum.
2. The composition according to claim 1, wherein the total amount of gellan gum, locust bean gum, and xanthan gum in the composition is 1.0% by mass or less.
3. The composition according to claim 1 or 2, which is a gel-like composition.
4. A composition according to any one of claims 1 to 3, for the prevention of oral frailty in the elderly.
5. The composition according to any one of claims 1 to 4, wherein the water content is 70% by mass or more.
6. The composition according to any one of claims 1 to 5, wherein the composition is filled into a cylindrical bottle with a diameter of 4 cm to a height of 5 cm, left to stand at 5°C for 17 hours, and the pressing pressure measured using a rheometer with a circular pressure-sensitive shaft of 3 cm in diameter at a sample stage movement speed of 10 mm / second is 1 to 40 N.
7. The composition according to any one of claims 1 to 6, wherein the amount of water released after being left at 40°C for 3 days (g / 20g) is less than 1.0g / 20g.