Accessories for injection devices, including a pivotable cover.

Abstract

An attachment (200) for an injection device (100) having a needle cap (190). The attachment (200) comprises a body portion (202) having a recess (220) adapted to receive the injection device (100), and a cover (204) coupled to the body portion (202). The cover (204) is pivotable between an open position in which the recess (220) is exposed to receive the injection device (100), and a closed position in which the cover (204) at least partially closes the recess to hold the injection device (100) to the body portion (202). The attachment (200) further comprises an uncapping device (234) having a gripping portion adapted to hold the needle cap (190). The uncapping device (234) is movable relative to the body portion (202).

Description

Technical Field

[0001] The present disclosure relates to accessories for an injection device.

Background Art

[0002] Needle safety devices are commonly used in combination with syringes during injections to reduce the risk of needle sticks due to accidents that can lead to the transmission of blood-borne pathogens. These needle safety devices are typically required to protect healthcare providers (HCPs), such as nurses, who often use syringes to inject patients. Needle safety devices can generally be classified as one of two types: (1) passive devices that automatically cover the needle after injection without requiring any additional steps from the user to activate the device, and (2) devices that require additional steps by the user to activate the needle safety feature.

[0003] For various reasons, users may fail to perform the additional actions required to activate non-passive devices, so needle safety devices are generally considered superior in terms of their ability to protect users from accidental needle sticks. Healthcare institutions and healthcare systems often require the use of needle safety devices in situations where HCPs perform injections. Additionally, needle safety devices are desirable for reducing the risk of injury, infection, and the spread of blood-borne pathogens to patients, family members, caregivers, and anyone who may come into contact with the injection device during the injection process and when disposing of the used syringe.

[0004] A commonly used example of a needle safety device is the UltraSafe® family of devices manufactured by Becton Dickinson. UltraSafe® consists of two plastic components and a spring assembled into a syringe along with a specially designed plunger rod. Once injection is complete, the plunger rod engages with a latch on the UltraSafe® housing component, moving the device and, via the spring, extending one of the housing components on the needle to lock it in place, creating a lockout position. An example of an UltraSafe® device is shown in Figures 1A and 1B.

[0005] Figure 1A shows the device in its ready-to-use state, i.e., the pre-injection position, before injection is administered. Figure 1B shows the device in its safe, used state, i.e., the lockout position, after injection is complete.

[0006] Figures 2A, 2B, 2C, and 2D show typical instructions for using the UltraSafe® device. As shown here, the procedure for using UltraSafe® is essentially the same as that for administering an injection using an exposed syringe. Pinching the skin and injecting at a 45-degree angle is essential to limit the injection depth, ensuring that the injection is subcutaneous and not administered intramuscularly (too deep) or intradermally (into the skin). Injections that are too shallow or too deep may affect the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs intended for subcutaneous injection.

[0007] As shown in Figures 2A to 2D, the process for properly using a syringe to administer a subcutaneous injection is complex and varies from user to user, which can lead to differences in injection depth and affect drug efficacy. Health care professionals (HCPs), such as nurses, are proficient in and trained in syringe-assisted injection techniques. However, techniques vary from nurse to nurse, which can impact pharmacokinetics (PK) and pharmacokinetics (PD). Furthermore, typical injection techniques require the use of both hands—pinching with one hand and injecting with the other—making it difficult for nurses to administer injections to difficult patients, such as children, who may move during the injection. Moreover, even when nurses have no problem using syringes, patients often fear syringes and needles, making injections a frequently unpleasant experience for them.

[0008] It is particularly difficult for patients and caregivers to use syringes such as UltraSafe™. This is not only because the procedure for use is complex, but also because syringes with exposed needles tend to cause anxiety in patients. [Overview of the Initiative] [Problems that the invention aims to solve]

[0009] Therefore, it is necessary to develop accessories that enable easier operation of needle safety devices, such as UltraSafe™. [Means for solving the problem]

[0010] In one aspect of the present invention, an accessory for an injection device having a needle cap is provided, the accessory comprising: a main body portion having a recess adapted for receiving an injection device; a cover connected to the main body portion, the cover being pivotable between an open position in which the recess is exposed and the injection device is received, and a closed position in which the cover at least partially closes the recess and holds the injection device to the main body portion; and a cap removal device having a gripping portion adapted for holding the needle cap, the cap removal device being movable relative to the main body portion, the cover comprising a proximal end adapted to be moved by a user to move the cover from the open position to the closed position, and a distal end adapted to move the gripping portion toward the end of the accessory to at least partially remove the needle cap from the injection device when the cover is moved from the open position to the closed position.

[0011] In this way, the needle cap can be automatically removed when the cover is closed. This is achieved by the cover acting as a lever that moves the cap removal device and causes the needle cap to be removed. This provides a simple and reliable mechanism for removing the needle cover in a way that even less dexterous users will find easy. In addition, the cover offers a mechanical advantage in moving the cap removal device to reduce the amount of force required by the user.

[0012] In another aspect of the present invention, an accessory for an injection device having a needle cap is provided, the accessory comprising: a main body portion having a recess adapted for receiving an injection device; a cover connected to the main body portion, the cover being pivotable between an open position in which the recess is exposed and receives an injection device and a closed position in which the cover at least partially closes the recess and holds the injection device to the main body portion; and a cap removal device having a gripping portion, the cap removal device having an expanded configuration in which the needle cap can pass between the gripping portions and a contracted configuration in which the gripping portions hold the needle cap and at least partially remove the needle cap from the injection device, the cover and the cap removal device being operably connected to each other such that when the cover is moved from the open position to the closed position, the cap removal device transitions from the expanded configuration to the contracted configuration.

[0013] In this way, the injection device can be loaded into the accessory without the gripping part interfering with the needle cap. Next, when the cover is closed, the gripping part closes over the needle cap to automatically remove it. After the cover is removed, the gripping part opens again to release the cover so that it can be separated from the accessory.

[0014] In another aspect of the present invention, an accessory for an injection device is provided, having a safety shield, at least one flange adapted to allow a user to grasp the injection device, and a syringe sheath movable from a pre-injection position to a lockout position relative to the at least one flange, the accessory comprising: a body portion having a recess adapted to receive the safety shield of the injection device and a slot adapted to receive at least one flange of the injection device; and a cover connected to the body portion, which is pivotable between an open position in which the recess and slot are exposed to receive the safety shield and flange of the injection device, respectively, and a closed position in which the recess and slot are at least partially closed to hold the injection device in the body portion, the slot being molded to resist distal and proximal movement of at least one flange relative to the body portion, and allowing the syringe sheath to move proximal to the body portion from a pre-injection position to a lockout position.

[0015] In this way, the cover can be opened to allow easier access to the recess and slot. When the cover is then closed, the slot holds the flange in place, but the syringe sheath remains movable and therefore does not interfere with the function of the injection device.

[0016] In another aspect of the present invention, an accessory for an injection device having a needle cap is provided, the accessory comprising: a body portion having a recess adapted for receiving an injection device; a cover connected to the body portion, the cover being pivotable between an open position in which the recess is exposed and receives an injection device and a closed position in which the cover at least partially closes the recess and holds the injection device in the body portion; and a cap removal device having a gripping portion adapted for holding a needle cap, the cap removal device being axially movable relative to the body portion from an initial position to an advanced position for removing a needle cap from an injection device, the body portion comprising a track, the cap removal device being positioned inside so as to move axially relative to the body portion, the track being adapted so as to be held relative to the track by the injection device when the injection device is positioned in the body portion.

[0017] In this way, the injection device performs the function of holding the needle cap removal device within the track. This avoids the need for additional components and simplifies the design and manufacturing.

[0018] The needle cap (often similarly called a "needle boot" or "needle shield") may be a rigid or non-rigid needle cap. A rigid needle cap may consist of at least two components, for example, a rigid outer shell and an inner body that surrounds the needle on the syringe when in place. The inner body may be a flexible inner body, an elastic inner body, or a pliable inner body. This inner body may be made of rubber. Alternatively, a non-rigid needle cap may be used, in which case the needle cap may be a single flexible body, an elastic body, or a pliable body, for example, a rubberized needle boot. [Brief explanation of the drawing]

[0019] Embodiments of the present invention will be described simply by reference to the following drawings. [Figure 1A] This is a perspective view of an injection device in a ready-to-use state before use. [Figure 1B] A perspective view of an injection device in a safe locked-out state. [Figure 2A] An example of a side view showing typical use of the injection device of FIG. 1. [Figure 2B] An example of a side view showing typical use of the injection device of FIG. 1. [Figure 2C] An example of a side view showing typical use of the injection device of FIG. 1. [Figure 2D] An example of a side view showing typical use of the injection device of FIG. 1. [Figure 3] A perspective view of an accessory of the injection device, with the accessory in a closed configuration. [Figure 4] A perspective view of the accessory in an open configuration. [Figure 5] A perspective view of the accessory in an open configuration with the injection device within the accessory. [Figure 6] A perspective view of the accessory in a closed configuration with the injection device within the accessory. [Figure 7] An internal view of the accessory without the injection device and cover. [Figure 8] An enlarged perspective view of the cap removal device and cover of the accessory in an open position, with the body portion not shown. [Figure 9] A further enlarged perspective view of the cap removal device and cover, with the body portion not shown. [Figure 10] A further perspective view of the accessory in an open configuration, with the injection device within the accessory. [Figure 11] A perspective view of the cap removal device and cover in a closed position, with the body portion not shown. [Figure 12] A perspective view of the base of the accessory. [Figure 13] An internal view of the body portion of the accessory. [Figure 14] A plan view of the cap removal device of the accessory. [Figure 15] A further perspective view of the body portion. [Modes for carrying out the invention]

[0020] Figures 1A and 1B show a manual injection device 100 suitable for use with the accessories of the present disclosure. The injection device 100 comprises a syringe 110 extending from a proximal end with a needle 130 to an open distal end. The open distal end of the syringe is sealed by a stopper 140. A needle cap 190 is provided to cover the needle 130.

[0021] The syringe 110 is secured within the syringe sheath 120 by a syringe locking element 125. The syringe locking element 125 may have diametrically opposed contact surfaces between which the flange of a standard syringe is restricted. Restricting the flange between the contact surfaces prevents the syringe 110 from moving relative to the syringe sheath 120.

[0022] The syringe sheath 120 has a distal opening end into which the syringe 110 can be inserted, and a proximal opening end from which the needle 130 extends when the syringe 110 is fixed inside the sheath 120. The safety shield 150 is movably mounted on the syringe sheath 120. The safety shield 150 is movable between a retracted position (shown in Figure 1A) where the needle 130 extends beyond the proximal end of the safety shield and an extended position (shown in Figure 1B) where the safety shield extends beyond the proximal end of the needle 130. In the second position shown in Figure 1B, the needle 130 is covered by the safety shield 150, thereby shielding the user from the needle and preventing accidental needle puncture injuries.

[0023] Since the user can grasp the injection device 100 equipped with a conventional dirt grip (shown in Figure 2), the safety shield 150 is provided with a flange 155 at or in that direction from its distal end. The flange 155 shown in Figure 1 extends from the safety shield 150.

[0024] The safety shield 150 is biased to its extended position relative to the syringe sheath 120 (shown in Figure 1B) by a biasing element 160. The biasing element 160, shown in Figures 1A and 1B, takes the form of a coil spring positioned between the syringe sheath 120 and the safety shield 150, thereby biasing the safety shield 150 proximal to the syringe sheath 120 and to its extended position.

[0025] The retractable locking mechanism 180 holds the safety shield 150 in its retracted position relative to the syringe sheath 120. The locking mechanism 180 is movable between a locked position (Figure 1A) in which it prevents the safety shield 150 from moving relative to the syringe sheath 120, and an unlocked position in which it no longer prevents the safety shield 150 from moving relative to the syringe sheath 120. Once the locking mechanism is moved to the unlocked position, the safety shield 150 moves toward its extended position under the influence of the coil spring 160 (Figure 1B).

[0026] In the apparatus shown in Figures 1A and 1B, the locking mechanism 180 between the safety shield 150 and the syringe sheath 120 takes the form of a pair of flexible latch arms 181 provided on the safety shield 150, which engage with opposing latch surfaces 183 on the syringe sheath 120. The flexible latch arms 181 are biased to a first position in which they are engaged with their individual latch surfaces 183, thus preventing the safety shield 150 from moving proximally relative to the syringe sheath 120. When the flexible latch arms 181 are moved against this bias, they disengage from their individual latch surfaces 183, thus allowing the safety shield 150 to move proximally relative to the syringe sheath 120.

[0027] The latch arm 181 is configured to be moved from a first position to a second position by the plunger rod 170. The plunger rod 170 has an elongated member at its proximal end configured to engage with the stopper 140, which moves the stopper 140 proximal along the longitudinal axis of the syringe body to deliver a volume of drug from the needle 130. At its distal end, or in that direction, the plunger rod 170 has an operating surface 175 on which the user can place their thumb or finger to drive the plunger rod 170 proximal to deliver the injectable drug. When the plunger rod 170 approaches or reaches the end of its movement within the syringe body, the operating surface 175 of the plunger rod 170 deflects the flexible latch arm 181 outward to a position where they are no longer engaged with the latch surface 183 on the syringe sheath 120. Thus, the locking mechanism is released at the end of the injection, and the safety shield 150 moves to its extended position.

[0028] Although not visible in the attached drawings, the manual injection device shown in Figures 1A and 1B may further be equipped with a safety lock to lock the safety shield 150 in its extended position after the injection is complete.

[0029] Referring to Figure 3, there is an accessory 200 for use with an injection device 100, such as an UltraSafe® device. In this specification, the accessory 200 is described using UltraSafe® as a specific example of the injection device 100. However, the accessory 200 may be used with other injection devices other than the UltraSafe® device. For example, the accessory may be used with an UltraSafe Plus® device. The structure of the accessory 200 may be modified to match the form factor of any suitable injection device.

[0030] The accessory 200 comprises a main body 202 and a cover 204. The accessory 200 has a distal end 206 for positioning toward or over the injection site when administering an injection, and a proximal end 208 opposite the distal end 206. The accessory 200 has a window 210 inside the cover 204. The main body 202 on the opposite side of the accessory 200 also has another window.

[0031] Referring to Figure 4, the cover 204 is connected to the main body portion 202. Specifically, the cover 204 is pivotally connected to the main body portion 202 around a pair of pivots 216. One of each pivot 216 is provided facing each side of the accessory 200. Each pivot 216 includes an opening 218 in the main body portion 202 through which a projection 203 in the cover 204 passes. Alternatively, the projection 203 may be located in the main body portion 202, and the opening 218 may be provided in the cover 204. The projection 203 is shown in detail in Figures 8 and 9. The projection 203 is rotatable within the opening 218, thereby allowing the cover 204 to rotate relative to the main body portion 202. In this way, the cover 204 is movable between an open position, as shown in Figure 4, and a closed position, as shown in Figure 3.

[0032] The openings 218 of each pivot portion 216 are provided on elastic mounting members 217 connected to the main body portion 202. In this example, the elastic mounting members 217 are integrally formed with the main body portion 202. The elastic mounting members 217 are positioned to bend relative to the main body portion 202, so that the cover 204 can be inserted between the pivot portions 216. This simplifies the assembly process. In addition, each projection 203 on the cover 204 has a longitudinal surface and a side surface. The side surface is inclined with respect to the longitudinal surface. In other words, the side surface is not perpendicular to the longitudinal surface. In this way, the projections assist in the bending of the elastic mounting members 217 when the cover 204 is mounted on the main body portion 202.

[0033] The main body portion 202 includes a recess 220 for receiving the injection device 100. Figure 5 shows the injection device 100 positioned within the recess 220, with the length of the safety shield 150 positioned longitudinally within the recess 220. Referring again to Figure 4, the main body portion 202 also includes a slot 222. The length of the slot 222 is positioned perpendicular to the longitudinal axis of the accessory 200. The slot 222 is fitted to receive the flange 155 of the injection device 100, as shown in Figure 5.

[0034] When the cover 204 is in the open position, the recess 220 and slot 222 are exposed to receive the injection device 100. Specifically, the recess 220 receives the safety shield 150 and the slot 222 receives the flange 155. As shown in Figure 6, once the injection device 100 is positioned within the recess 220 and slot 222, the cover 204 is moved from the open position to the closed position. The injection device 100 and its accessories 200 are now ready to administer an injection. The user can then place the accessories 200 housing the injection device on the injection site, e.g., on the skin, and operate the actuation surface 175 with one hand to administer the injection in a safe, simple, and reliable manner.

[0035] When the cover 204 is in the closed position, the cover 204 closes the recess 220 and slot 222 to hold the injection device 100 in the main body portion 202. Once the injection device 100 is held within the accessory 200 by the cover 204 and the main body portion 202, the injection device 100 can be viewed through the windows 210 provided on each side of the accessory 200. This allows the user to examine the contents of the syringe before administering an injection.

[0036] Referring to Figures 4 and 5, the slot 222 is molded to resist the movement of the flange 155 toward the distal end 206 of the accessory 200. In other words, the slot 222 is molded to prevent the flange 155 from moving distally. The slot 222 is also molded to resist the movement of the flange 155 toward the proximal end 208 of the accessory 200. In other words, the slot 222 is molded to prevent the flange 155 from moving proximal. However, the slot 222 is molded to allow the syringe sheath 120 of the injection device 100 to move proximal to the body portion 202. This allows the injection device 100 to move from the pre-injection position to the lockout position, as described above. In this particular embodiment, there is a cavity formed within the body portion 202 and the cover 204 through which the syringe sheath can move. However, the width of this cavity is such that the flange 155 cannot move through the cavity, and therefore, while the cover 204 is in the closed position, the flange 155 is held within the slot 222.

[0037] Referring again to Figure 3, the main body portion 202 and the cover 204 are joined together to form a pair of opposing sides. The right side 212 is shown in Figure 3. The opposing left side is not shown, but it is a mirror image of the right side 212. The accessory 200 has a pair of opposing surfaces. The front surface 214 is shown in Figure 3. The opposing back surface is not shown. Each of the opposing surfaces has a similar surface area, and each has a larger surface area than the respective opposing side. The cover 204 forms part of the front surface 214, and the main body portion 202 forms the back surface. These surfaces and sides connect the distal end 206 of the accessory 200 to the proximal end 208 of the accessory 200.

[0038] The injection device 100 is positioned in the recess 220 by lowering it diagonally into the recess 220. The direction in which the injection device 100 is moved toward the accessory 200 so that it is positioned in the recess 220 has a component perpendicular to the longitudinal axis of the accessory 200 and a component parallel to the longitudinal axis of the accessory 200. This direction extends toward the rear surface of the main body portion 202. Specifically, the slot 222 and the recess 220 each have an open surface parallel to the surface of the accessory 200 into which the injection device 100 is lowered. Since the surface of the accessory 200 has a larger surface area than the side surface, this indicates a larger area for the user to target when positioning the injection device 100 within the accessory 200. This makes it easier for users, especially those with dexterity issues, to position the injection device 100.

[0039] Referring to Figure 4, the slot 222 is provided with a pair of distal contact portions 224 on either side of the main body portion 202. The distal contact portions 224 are fixed to the main body portion 202, and one of each distal contact portion 224 resists distal movement of one of the flanges 155. The distal contact portions 224 are integrally formed with the main body portion 202, resulting in a secure connection that is easy to manufacture. However, the main body portion 202 may be a modular component in which the distal contact portions 224 are removable from the main body portion 202. Each distal contact portion 224 has a flat upper surface that extends into a curved lower surface. This reflects the shape of the lower outer surface of the flange and helps to securely fix the injection device 100 to the main body portion 202.

[0040] Slot 222 also includes a pair of proximal contact portions 226. The proximal contact portions 226 are fixed to the main body portion 202, and one of each proximal contact portion 226 resists proximal movement of one of the flanges 155. The proximal contact portions 226 are each integrally formed with the main body portion 202, resulting in a secure connection that is easy to manufacture. However, the main body portion 202 may be a modular component in which the proximal contact portions 226 are removable from the main body portion 202. Each proximal contact portion 226 has a flat lower surface for interacting with one of the upper surfaces of the flange 155. The proximal contact portions 226 are spaced apart from each other to form a cavity through which the syringe sheath 120 can move.

[0041] Referring to Figure 4, the cover 204 has a cover slot 228. The cover slot 228 is positioned to hold the flange 155 when the cover 204 moves from the open position shown in Figure 4 to the closed position shown in Figure 6. The cover slot 228 is molded to resist the flange 155 moving toward the distal end 206 of the accessory 200 when the cover 204 is in the closed position. In other words, the cover slot 228 is molded to prevent the flange 155 from moving distally. The cover slot 228 is also molded to resist the flange 155 moving toward the proximal end 208 of the accessory 200. In other words, the cover slot 228 is molded to prevent the flange 155 from moving proximal. However, the cover slot 228 is molded to allow the syringe sheath 120 of the injection device 100 to move proximal to the main body portion 202. This allows the injection device 100 to move from the pre-injection position to the lockout position, as described above. In this particular example, the cover slot 228 works in cooperation with the slot 222 of the main body portion 202 to form a cavity through which the syringe sheath 120 can move. However, the width of the cavity is such that the flange 155 cannot move through the cavity, and therefore the flange 155 is held within the cover slot 228 while the cover 204 is in the closed position.

[0042] The cover slot 228 also includes a pair of distal contact portions 230 on either side of the cover 204. The distal contact portions 230 are fixed to the cover 204, and one of each distal contact portion 230 resists distal movement of one of the flanges 155. The distal contact portions 230 are each integrally formed with the cover 204, providing a secure connection that is easy to manufacture. However, the cover 204 may be a modular component in which the distal contact portions 230 are removable from the cover 204. As shown in Figure 4, each distal contact portion 230 includes a rib extending along the length of the cover 204, thus providing structural support to the cover 204.

[0043] The cover slot 228 also includes a pair of proximal contact portions 232. The proximal contact portions 232 are fixed to the cover 204, and one of each proximal contact portion 232 resists proximal movement of one of each flange 155. The proximal contact portions 232 are formed integrally with the cover 204, resulting in a secure connection that is easy to manufacture. However, the cover 204 may be a modular component in which the proximal contact portions 232 are removable from the cover 204.

[0044] Referring to Figures 7 and 8, the accessory 200 includes a cap removal device 234 for removing the needle cap 190 from the injection device 100. In this example, the cap removal device 234 comprises a pair of movable elements 236, each having a gripping end for interacting with the needle cap 190. Each gripping end is molded to match the outer surface of the needle cap 190. Each gripping end has a concave end for engaging with the cylindrical outer shape of the needle cap 190. In this example, the movable elements 236 are integrally formed with the cap removal device 234. However, the movable elements 236 may be provided as separate components that bend or rotate relative to the cap removal device 234. For example, each movable element 236 may be mounted on the cap removal device 234 around a pivot. The needle cap 190 may be a rigid needle cap or a non-rigid needle cap. A rigid needle cap may be formed of at least two components, for example, a rigid outer shell and an inner body that surrounds the needle 130 on the syringe 110 when in a predetermined position. The inner body may be a flexible inner body, an elastic inner body, or a pliable inner body. This inner body may be made of rubber. Alternatively, a non-rigid needle cap may be used, in which case the needle cap may be a single flexible body, an elastic body, or a pliable body, for example, a rubberized needle boot. In the case of a non-rigid needle cap, the cap removal device 234 is adapted to elastically grip the non-rigid needle cap during cap removal, for example, between a pair of movable elements 236. Because the cap is non-rigid, it deforms within the cap removal device 234, particularly within the gripping portion, so that the gripping portion is tight and snug, and thus the removal of the cap is reliably achieved.

[0045] In this example, the cap removal device 234 has an extended configuration (as shown in Figure 8) and a retracted configuration (not shown). In the extended configuration, the cap removal device 234 does not interact with the needle cap 190. Specifically, the needle cap 190 can pass through the movable element 236, i.e., when the cap removal device 234 is in the extended configuration, for example, when the injection device 100 is inserted into the recess 220. In the retracted configuration, the cap removal device 234 holds the needle cap 190 so that the cap removal device 234 can remove the needle cap 190 from the injection device 100. Specifically, the movable elements 236 move toward each other to take the retracted configuration in which the cap removal device 234 grips the needle cap 190 via its gripping end. When the cover 204 is in the open position, the cap removal device 234 is in the extended position. By closing the cover 204, the cap removal device 234 assumes a retracted configuration when sliding forward to remove the needle cap 190. However, the cap removal device 234 assumes an expanded configuration again to release the needle cap 190 when the cover 204 is completely closed (as shown in Figure 6).

[0046] In this particular example, the gripping part has two configurations: an expanded configuration and a contracted configuration. However, in another example, the gripping part may be in the contracted configuration by default. In this case, the gripping part holds the needle cap 190 when the injection device 100 is placed inside the accessory 200, and there is no need to switch from the expanded configuration to the contracted configuration. This option may be simpler to manufacture. However, when the gripping part is in the expanded configuration, the injection device 100 can be inserted into the accessory 200 without resistance from the gripping part. In another example, the gripping part may have only one movable element that pushes the needle cap toward a non-movable element.

[0047] The cap removal device 234 comprises a pair of guides 240, each positioned within the tracks of the main body portion 202. The cap removal device 234 is positioned to slide within the tracks of the main body portion 202.

[0048] Referring to Figures 9 and 10, the cap removal device 234 comprises a pair of cap removal device slots 242, each provided on one side of the cap removal device 234. To move the cover 204 from an open position to a closed position, the cover 204 comprises a proximal end 244 that can be moved by the user. To move the gripping portion, including the cap removal device 234 and the movable element 236, distally, the cover 204 also comprises a distal end 246 that is operably connected to the cap removal device 234.

[0049] In this example, there is a pair of distal ends 246 of the cover 204, each equipped with a cover cam 243 located inside one of the cap removal device slots 242. In this way, each distal end 246 engages with one of the respective cap removal device slots 242 to translate the cap removal device 234 distally as the cover 204 pivots from the open position to the closed position. Figure 11 shows the cover 204 in the closed position, with the cap removal device 234 moved distally.

[0050] Referring to Figure 9, the cover 204 comprises a pair of distal extensions, each extending distally from each pivot 216. The distal end 246 and the cover cam 243 are located on the distal extensions. There is a pair of proximal extensions, each corresponding to one of the distal extensions. Each proximal extension extends proximally from each pivot 216, thereby forming two sides of the proximal end 244 of the cover 204.

[0051] Each proximal extension is longer than each distal extension. This helps to provide a mechanical advantage with respect to the pivot 216, and therefore the cover 204 can be closed more easily. This movement is also particularly important because it moves the cap removal device 234 distally to remove the needle cap 190.

[0052] Referring to Figures 8 and 14, one of each of the movable elements 236 of the gripping section is made of a flexible elastic material. This allows the gripping section to transition between an expanded configuration in which the needle cap 190 can pass through the gripping section, and a contracted configuration in which the gripping section holds the needle cap 190 to remove it from the injection device 100. A cap removal device cam 248 is present on the outer surface of one of the movable elements 236. Each cap removal device cam 248 engages with the cap removal device cam surface 250 of the main body section 202 when the cap removal device 234 is moved distally by the cover 204. The cap removal device cam surface 250 is shown in Figures 12 and 13. The cap removal device 234 also includes a pair of receiving slots, each adapted to receive at least a portion of the cover 204 when the cover 204 is in the closed position.

[0053] The cap removal device cam 248 is pressed against the cap removal device cam surface 250, and the cap removal device 234 moves distally. This causes the movable elements 236 to push toward each other to transition the gripping portion from an extended configuration to a retracted configuration. Thus, when the injection device 100 is in the recess 200, the movable elements 236 grip the needle cap 190. At the same time, the cap removal device 234 moves distally, and therefore pulls the needle cap 190 distally and away from the injection device 100. This removes the needle cap 190 from the injection device 100.

[0054] Referring to Figures 12 and 13, each of the cap removal device cam surfaces 250 is molded such that the gripping portion transitions from an expanded configuration to a contracted configuration and then back to an expanded configuration as the cover 204 moves from an open position to a fully closed position. In this example, each of the cap removal device cam surfaces 250 has a proximal end 252 and a distal end 254 that do not interact with each of the cap removal device cams 248, and an intermediate portion 256 positioned to interact with each of the cap removal device cams 248 in order to move the movable element 236 as the cap removal device 234 moves distally.

[0055] Figure 8 shows the cover 204 in the fully open position, with the cam removal device 234 in the extended configuration. Figure 12 shows the cover 204 in the fully closed position, with the cam removal device returning from the retracted configuration to the extended configuration as the cover 204 moves from the fully open position to the fully closed position.

[0056] Referring to Figure 15, the main body portion 202 includes a pair of tracks 258 for receiving each guide 240 of the cap removal device 234. Each track 258 is fitted so that the cap removal device 234 does not come out of the track when the injection device 100 is positioned on the main body portion 202. This is shown in Figure 10. Specifically, the injection device 100 holds the cap removal device 234 within each track 258 when the injection device 100 is in the recess 220.

[0057] Each track 258 is configured such that, when the injection device 100 is not positioned on the main body portion 202, the cap removal device 234 can move in a direction having components perpendicular to the axial direction (i.e., the longitudinal direction extending from the proximal end 208 to the distal end 206 of the accessory 200). However, when the injection device 100 is positioned on the main body portion 202, the cap removal device 234 is pressed against each track 258 by the injection device 100, and as a result, the cap removal device 234 can only slide axially relative to the main body portion 202.

[0058] As shown in Figure 7, each track exposes at least a portion of the cap removal device 234 so that when the injection device 100 is positioned in the recess 220, the injection device 100 holds the cap removal device 234 at least partially within the track 258. As shown in Figure 10, each track 258 does not include any means adapted to contact the upper surface of the cap removal device 234, so the track 258 exposes the cap removal device 234. In other words, the body portion 202 does not have a lip or other such retaining means for holding the cap removal device 234. Instead, the injection device 100 holds the cap removal device 234 within the track 258. Specifically, the cap removal device 234 comes into direct contact with the injection device 100 when the injection device 100 is positioned in the recess 220. This simplifies the design of the accessory 200.

[0059] Referring to Figure 15, each track 258 comprises a base 260 and a pair of side walls 264, 266 adapted to guide each side of the cap removal device 234. In this example, the pair of side walls 264, 266 are formed integrally with the main body portion 202. However, in another example, one or both of the side walls 264, 266 are separate components from the main body portion 202. One of the first side walls 266 of each track 258 defines the wall of a window 268 from which the injection device 100 can be seen when the injection device 100 is inside the accessory 200. One of the second side walls 264 of each track 258 defines the outer side wall of the accessory 200. The base 260 and / or side walls 264, 266 of each track 248 are formed integrally with the main body portion 202.

[0060] The features of the accessory 200 described above are that it is inexpensive, simple, and easy to use. In addition, it is possible to operate the accessory 200 with one hand when administering an injection using the injection device 100.

[0061] When used, the above injection device is intended for the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency, poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, or myelodysplasia, or for the expression of protective immunity, and contains antibodies (monoclonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, silkumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab, or Substances such as these biosimilar versions, etanercept, abatacept, anakinra, epoetin alfa, darbepoetin alfa, epoetin beta-methoxypolyethylene glycol, peginesatide, hormones, antitoxins, pain control agents, thrombosis control agents, infection control or elimination agents, peptides, proteins, human insulin or human insulin analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic agents, antihistamines, anti-inflammatory agents, corticosteroids, disease-modifying antirheumatic agents, erythropoietin, or vaccines may be contained in and used for delivery. In addition to these substances, any drugs contained in the infusion device may also contain other substances such as inactive components, as will be understood by those skilled in the art. Naturally, as is well known in the art, it will be understood by those skilled in the art that certain substances are effective for use in the treatment or prevention of certain conditions. For example, antiallergic drugs are known to be effective in treating or preventing allergies, antihistamines are known to be effective in treating or preventing hay fever, and anti-inflammatory drugs are known to be effective in treating or preventing inflammation. Therefore, any selection of one or more of the substances listed herein or in the claims for use in treating or preventing one or more conditions in which these substances (including multiple substances) are known to be effective is conceivable.However, in certain examples, golimumab is known to be effective for use in the treatment or prevention of one or more of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or ulcerative colitis, or any combination of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis, or all of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis.

[0062] Golimumab may optionally be used in combination with one or more inactive ingredients, such as L-histidine, L-histidine monohydrochloride monohydrate, sorbitol, polysorbate 80, and water, or any or all of them. Golimumab may be present in a composition in which golimumab is the sole active ingredient. For example, golimumab may be administered as SIMPONI®.

[0063] The term “comprising” encompasses “including” and “consisting,” for example, a composition “comprising” X may consist exclusively of X, but may also include some additional components, such as X + Y. Unless otherwise specified, each embodiment described herein may be combined with other embodiments described herein. In the particular embodiments described above, a specific pair of components was provided to achieve a particular function. However, it is possible to achieve these functions using at least one of these components.

[0064] It will be understood that the above benefits and advantages may relate to one embodiment or to several embodiments. Embodiments are not limited to those that solve any or all of the problems described or that have any or all of the benefits and advantages described. A reference to an item refers to one or more of those items.

[0065] The above description of preferred embodiments is given merely as examples, and it will be understood that various modifications may be made by those skilled in the art. Although various embodiments have been described above with some degree of specificity or by reference to one or more individual embodiments, those skilled in the art can make many changes to the disclosed embodiments without departing from the scope of the invention.

[0066] List of numbered embodiments 1. An accessory for an injection device having a needle cap, the accessory is, A main body portion having a recess adapted for receiving an injection device, A cover connected to the main body, the cover being pivotable between an open position in which a recess is exposed and a syringe is received, and a closed position in which the cover at least partially closes the recess and holds the syringe to the main body, A cap removal device comprising a gripping portion adapted to hold a needle cap, wherein the cap removal device comprises a cap removal device that is movable relative to the main body portion, The cover is, A proximal end that is moved by the user and adapted to move the cover from an open position to a closed position, An accessory comprising a distal end adapted to move a gripping portion toward the end of the accessory when the cover is moved from an open position to a closed position, thereby at least partially removing the needle cap from the injection device.

[0067] 2. The accessory according to Embodiment 1, wherein the cover is connected to the main body portion around at least one pivot point.

[0068] 3. At least one pivot part, At least one opening in the main body, The accessory according to Embodiment 2, comprising at least one projection within the cover, the at least one projection being rotatable within the opening.

[0069] 4. The accessory according to Embodiment 2 or Embodiment 3, wherein the cover comprises at least one distal extension extending distally from at least one pivot, and the distal end of the cover is provided at the end of the distal extension.

[0070] 5. The accessory according to any one of embodiments 2 to 4, wherein the cover comprises a proximal extension extending proximally away from at least one pivot.

[0071] 6. The accessory described in Embodiments 4 and 5, wherein the distal extension is shorter than the proximal extension.

[0072] 7. The accessory according to any one of embodiments 1 to 6, wherein the distal end of the cover is provided with a cover cam located in a cap removal device slot of the cap removal device.

[0073] 8. The accessory according to Embodiment 7, wherein the rotation of the cover cam about a pivot axis causes the cover cam to act against the cap removal device slot in order to translate the cap removal device within the accessory.

[0074] 9. The accessory according to Embodiment 7 or Embodiment 8, wherein the cover pivots from an open position to a closed position to move the cap removal device toward the distal end of the accessory, and is positioned to cause the cover cam to act against the cap removal device slot.

[0075] 10. The accessory according to Embodiment 9, wherein the gripping portion is positioned to hold the needle cap while the cap removal device slot moves toward the distal end of the accessory, thereby at least partially removing the needle cap from the injection device.

[0076] 11. The accessory according to any one of embodiments 7 to 10, wherein the cover pivots from a closed position to an open position to move the cap removal device toward the proximal end of the accessory, and is positioned to cause the cover cam to act against the cap removal device slot.

[0077] 12. The cover is an accessory according to any one of embodiments 1 to 11, which is connected to the main body by a pair of pivots.

[0078] 13. The accessory according to Embodiment 12, wherein each of a pair of pivot parts comprises an opening in the main body and a protrusion within the cover, the protrusion being rotatable within the opening.

[0079] 14. The accessory according to Embodiment 12 or Embodiment 13, wherein the cover comprises a pair of distal extensions that extend distally from each of the pair of pivots.

[0080] 15. The accessory according to any one of embodiments 12 to 14, wherein the cover comprises a pair of proximal extensions, each extending proximal away from each of the pair of pivots.

[0081] 16. The accessory according to Embodiments 14 and 15, wherein each distal extension is shorter than the corresponding proximal extension.

[0082] 17. Embodiment 14, and optionally the accessory according to Embodiment 15 and / or Embodiment 16, further comprising a pair of distal ends of a cover, each provided at one end of the distal extension, the one distal end of which is operably connected to a cap removal device to move a gripping portion toward the end of the accessory, thereby at least partially removing the needle cap from the injection device when the cover is moved from an open position to a closed position.

[0083] 18. The accessory according to Embodiment 17, wherein each distal end of the cover is provided with a cover cam located in a corresponding cap removal device slot of the cap removal device.

[0084] 19. The accessory according to Embodiment 18, wherein the rotation of each cover cam about a pivot axis causes each cover cam to act against the corresponding cap removal device slot in order to translate the cap removal device within the accessory.

[0085] 20. The accessory according to Embodiment 18 or Embodiment 19, wherein the cover pivots from an open position to a closed position to move the cap removal device toward the distal end of the accessory, and is positioned to cause each cover cam to act against the corresponding cap removal device slot.

[0086] 21. The accessory according to Embodiment 20, wherein the gripping portion is positioned to hold the needle cap while the cap removal device slot moves toward the distal end of the accessory, thereby removing the needle cap from the injection device.

[0087] 22. The accessory according to any one of embodiments 18 to 21, wherein the cover pivots from a closed position to an open position to move the cap removal device toward the proximal end of the accessory, and is positioned to cause each cover cam to act against the corresponding cap removal device slot.

[0088] 23. The accessory according to any one of embodiments 1 to 22, wherein the cap removal device has an expansion configuration that allows the needle cap to pass between the gripping portions, and a contraction configuration in which the gripping portions hold the needle cap and remove the needle cap at least partially from the injection device.

[0089] 24. The accessory according to Embodiment 23, wherein the cover and cap removal device are operably connected to each other such that when the cover is moved from an open position to a closed position, the cap removal device transitions from an extended configuration to a retracted configuration.

[0090] 25. The accessory according to Embodiment 23 or Embodiment 24, wherein the cap removal device is positioned to return to an extended configuration and release the needle cap when the cover reaches the closed position.

[0091] 26. The accessory according to any one of embodiments 23 to 25, wherein the gripping portion comprises at least one movable element adapted to hold the needle cap when the cap removal device is in a retracted configuration and to be offset from the needle cap when the cap removal device is in an extended configuration.

[0092] 27. The accessory according to Embodiment 26, wherein at least one movable element is formed of a flexible elastic material, and the flexible elastic material allows at least one movable element to move between a position in which the gripping portion holds the needle cap and a position in which the needle cap can pass between the gripping portion.

[0093] 28. The accessory according to Embodiment 27, wherein at least one movable element is configured to bend between a position in which the gripping portion holds the needle cap and a position in which the needle cap can pass between the gripping portions.

[0094] 29. The accessory according to any one of embodiments 23 to 28, further comprising at least one cap removal device cam arranged to interact with at least one cap removal device cam surface in order to transition the cap removal device from an extended configuration to a retracted configuration.

[0095] 30. At least one cap removal device cam is connected to or mounted on at least one movable element, the accessory according to Embodiment 26, Embodiment 29, and optionally Embodiment 28 and / or Embodiment 27.

[0096] 31. The cap removal device cam surface is an accessory as described in Embodiment 29 or Embodiment 30, which is connected to the main body portion or provided on the main body portion.

[0097] 32. The accessory according to any one of embodiments 29 to 31, wherein at least one cap removal device cam surface is arranged to interact with the cap removal device cam to transition the cap removal device from an extended configuration to a retracted configuration and back to an extended configuration as the cap removal device cam moves over and through the cap removal device cam surface.

[0098] 33. The accessory according to any one of embodiments 29 to 32, wherein at least one cap removal device cam and at least one cap removal device cam surface are offset from each other when the cover is in the open position.

[0099] 34. The accessory according to any one of embodiments 29 to 33, wherein the movement of the cover from the open position to the closed position moves the cap removal device cam to engage with the cap removal device cam surface, and as a result the cap removal device transitions from an extended configuration to a retracted configuration.

[0100] 35. The attachment according to any one of embodiments 23 to 34, wherein the gripping portion comprises at least one gripping end molded to match the outer surface of the needle cap.

[0101] 36. The accessory according to any one of embodiments 23 to 35, wherein the gripping portion comprises a pair of movable elements adapted to hold the needle cap when the cap removal device is in a retracted configuration and to be offset from the needle cap when the cap removal device is in an extended configuration.

[0102] 37. The accessory according to Embodiment 36, wherein one of each of a pair of movable elements is formed of a flexible elastic material, the flexible elastic material making each movable element movable between a position in which the gripping portion holds the needle cap and a position in which the needle cap can pass between the gripping portions.

[0103] 38. The accessory according to Embodiment 36 or Embodiment 37, wherein one of each of the pair of movable elements is configured to bend between a position in which the gripping portion holds the needle cap and a position in which the needle cap can pass between the gripping portions.

[0104] 39. The accessory according to any one of embodiments 23 to 36, further comprising a pair of cap removal device cams, each positioned to interact with one of the respective cap removal device cam surfaces of the pair, to transition the cap removal device from an extended configuration to a retracted configuration.

[0105] 40. Each cap removal device cam is connected to or mounted on one of the movable elements, as described in Embodiments 36, 39, and optionally in Embodiments 37 and / or 38.

[0106] 41. The cam surface of each cap removal device is connected to or provided on the main body, as described in Embodiment 39 or Embodiment 40.

[0107] 42. The accessory according to any one of embodiments 39 to 41, wherein the cap removal device cam surface is arranged such that, as the cap removal device cam moves and passes over each cap removal device cam surface, it transitions the cap removal device from an extended configuration to a retracted configuration and then back to an extended configuration.

[0108] 43. The accessory according to any one of embodiments 39 to 42, wherein each cap removal device cam and the corresponding cap removal device cam surface are offset from each other when the cover is in the open position, and as a result the cap removal device cam and the cap removal device do not join to each other.

[0109] 44. The accessory according to any one of embodiments 39 to 43, wherein the movement of the cover from the open position to the closed position moves each cap removal device cam to engage with the corresponding cap removal device cam surface, and as a result the cap removal device transitions from an extended configuration to a retracted configuration.

[0110] 45. The attachment according to any one of embodiments 23 to 44, wherein the gripping portion comprises a pair of gripping ends, each molded to match the outer surface of the needle cap.

[0111] 46. ​​The accessory is for an injection device having a safety shield and at least one flange adapted to allow a user to grasp the injection device, and a syringe sheath that is movable from a pre-injection position to a lockout position relative to at least one flange, wherein the main body portion further comprises a slot adapted to receive at least one flange of the injection device, as described in any one of embodiments 1 to 45.

[0112] 47. The accessory according to embodiment 46, wherein the recess and slot are exposed when the cover is in the open position to receive the safety shield and at least one flange, respectively.

[0113] 48. The accessory according to Embodiment 46 or Embodiment 47, wherein the cover, when the cover is in the closed position, at least partially closes the recess and slot to hold the injection device within the accessory.

[0114] 49. The accessory according to any one of embodiments 46 to 48, wherein the slot is molded to resist the distal and proximal movement of at least one flange relative to the main body, and to allow the syringe sheath to move proximal to the main body from a pre-injection position to a lockout position.

[0115] 50. The distal end of an accessory adapted to be positioned toward the injection site, and the proximal end of the opposing accessory, The accessory according to any one of embodiments 46 to 49, further comprising a pair of opposing surfaces and a pair of opposing side surfaces connecting the distal ends of the proximal ends of the accessory.

[0116] 51. The accessory according to Embodiment 50, wherein each of the opposing surfaces has a larger surface area than each of the opposing sides.

[0117] 52. An accessory according to Embodiment 50 or Embodiment 51, wherein one of the opposing surfaces is provided with a cover.

[0118] 53. The accessory according to any one of embodiments 50 to 52, wherein the slot and recess each have an open surface parallel to the surface of the accessory.

[0119] 54. The accessory according to any one of embodiments 46 to 53, wherein the recesses and slots are arranged to receive the injection device as the injection device moves in a direction perpendicular to the longitudinal axis of the accessory.

[0120] 55. The accessory according to any one of embodiments 46 to 54, wherein the slot comprises at least one distal contact portion, wherein at least one flange is positioned to resist distal movement relative to the accessory.

[0121] 56. The accessory according to embodiment 55, wherein at least one distal contact portion of the slot is integrally formed with the main body portion.

[0122] 57. The accessory according to Embodiment 55 or Embodiment 56, wherein the shape of at least one distal contact portion matches at least partially the shape of the lower surface of at least one flange.

[0123] 58. The accessory according to any one of embodiments 46 to 57, wherein the slot comprises at least one proximal contact portion, which is positioned to resist the proximal movement of at least one flange relative to the accessory.

[0124] 59. The accessory according to embodiment 58, wherein at least one proximal contact portion of the slot is integrally formed with the main body portion.

[0125] 60. The accessory according to any one of embodiments 46 to 59, wherein the cover resists movement of at least one flange distally and proximally relative to the accessory, but the syringe sheath has a cover slot that is molded to allow movement proximal to the accessory from a pre-injection position to a lockout position.

[0126] 61. The accessory according to embodiment 60, wherein the cover slot is formed inside the cover.

[0127] 62. The accessory according to embodiment 61, wherein the cover slot comprises at least one distal contact portion, wherein at least one flange is positioned to resist distal movement relative to the accessory.

[0128] 63. The accessory according to embodiment 62, wherein at least one distal contact portion of the cover slot is integrally formed with the cover.

[0129] 64. The accessory according to any one of embodiments 60 to 63, wherein the cover slot comprises at least one proximal contact portion, wherein at least one flange is positioned to resist proximal movement relative to the accessory.

[0130] 65. The accessory according to embodiment 64, wherein at least one proximal contact portion of the cover slot is integrally formed with the cover.

[0131] 66. The accessory is for an injection device having a pair of flanges adapted to allow a user to grasp the injection device, as described in any one of embodiments 46 to 65.

[0132] 67. The accessory according to embodiment 66, wherein the slot comprises a pair of distal contact portions, each positioned to resist distal movement of each flange of the pair of flanges relative to the accessory.

[0133] 68. The accessory described in Embodiment 67, wherein a pair of distal contact portions are integrally formed with the main body portion.

[0134] 69. The accessory according to Embodiment 67 or Embodiment 68, wherein the shape of each of the pair of distal contact portions matches at least partially the shape of the lower surface of each of the pair of flanges.

[0135] 70. The accessory according to any one of embodiments 66 to 69, wherein the slot comprises a pair of proximal contact portions, each positioned to resist proximal movement of each flange of the pair of flanges relative to the main body portion.

[0136] 71. The accessory according to embodiment 70, wherein a pair of proximal contact portions are integrally formed with the main body portion.

[0137] 72. The accessory according to any one of embodiments 60 to 71, wherein the cover slot comprises a pair of distal contact portions arranged to resist the distal movement of a pair of flanges relative to the main body portion.

[0138] 73. The accessory according to embodiment 72, wherein the pair of distal contact portions of the cover slot are integrally formed with the cover.

[0139] 74. The accessory according to any one of embodiments 60 to 73, wherein the cover slot comprises a pair of proximal contact portions arranged to resist the movement of a pair of flanges in the proximal direction relative to the main body portion.

[0140] 75. The accessory according to embodiment 74, wherein the pair of proximal contact portions of the cover slot are integrally formed with the cover.

[0141] 76. The main body is equipped with tracks arranged so that the cap removal device moves in translation. The accessory according to any one of embodiments 1 to 75, wherein the track exposes at least a portion of the cap removal device so that the injection device holds the cap removal device at least partially within the track when the injection device is positioned in the recess.

[0142] 77. The accessory according to embodiment 76, wherein the track is configured such that the cap removal device comes into direct contact with the injection device when the injection device is positioned in the recess.

[0143] 78. The accessory according to Embodiment 76 or Embodiment 77, wherein the track does not include means adapted to contact the upper surface of the cap removal device.

[0144] 79. The attachment according to any one of embodiments 76 to 78, wherein the track comprises a base and at least one side wall.

[0145] 80. Track is, A base adapted to guide the underside of the cap removal device, An accessory according to any one of embodiments 76 to 79, comprising at least one side wall adapted to guide the side of a cap removal device.

[0146] 81. The accessory according to embodiment 80, wherein at least one side wall defines a window wall from which the injector can be viewed when the injector is inside the accessory.

[0147] 82. The accessory according to embodiment 80, wherein at least one side wall defines the outer side wall of the accessory.

[0148] 83. An accessory according to any one of embodiments 80 to 82, wherein the base and / or at least one side wall is formed integrally with the main body portion.

[0149] 84. The accessory according to any one of embodiments 80 to 83, comprising a pair of side walls adapted to guide each side of the cap removal device.

[0150] 85. An accessory according to any one of embodiments 80 to 84, wherein a pair of side walls are integrally formed with the main body portion.

[0151] 86. The main body is equipped with a pair of tracks arranged so that the cap removal device moves in translation. The accessory according to any one of embodiments 76 to 85, wherein each track exposes at least a portion of the cap removal device so that the injection device holds at least partially the cap removal device within each track when the injection device is positioned in the recess.

[0152] 87. The accessory according to Embodiment 86, wherein each track is configured such that the cap removal device comes into direct contact with the injection device when the injection device is positioned in the recess.

[0153] 88. The accessory according to Embodiment 86 or Embodiment 87, wherein each track does not have means adapted to contact the upper surface of the cap removal device.

[0154] 89. An accessory according to any one of embodiments 86 to 88, wherein each track comprises a base and at least one side wall.

[0155] 90. Each track is, A base adapted to guide the underside of the cap removal device, An accessory according to any one of embodiments 86 to 89, comprising at least one side wall adapted to guide the side of a cap removal device.

[0156] 91. The accessory according to embodiment 90, wherein at least one side wall of each track defines a window wall from which the injector can be viewed when the injector is inside the accessory.

[0157] 92. The accessory according to embodiment 90, wherein at least one side wall of each track defines the outer side wall of the accessory.

[0158] 93. The base and / or at least one side wall of each track is formed integrally with the main body portion, as described in any one of embodiments 90 to 92.

[0159] 94. The accessory according to any one of embodiments 90 to 93, wherein each track comprises a pair of side walls adapted to guide each side of the cap removal device.

[0160] 95. An accessory according to any one of embodiments 90 to 94, wherein a pair of side walls of each track are integrally formed with the main body.

[0161] 96. The cap removal device is an accessory according to any one of embodiments 76 to 95, comprising a guide adapted to be positioned within the truck.

[0162] 97. The cap removal device is an accessory according to any one of embodiments 1 to 96, comprising at least one receiving slot adapted to receive at least a portion of the cover when the cover is in the closed position.

[0163] 98. The cap removal device comprises a pair of receiving slots, each adapted to receive at least a portion of the cover when the cover is in the closed position, as an accessory according to any one of embodiments 1 to 97.

[0164] 99. The accessory according to any one of embodiments 1 to 98, wherein the main body portion comprises at least one elastic mounting member adapted to connect the cover to the main body portion.

[0165] 100. The accessory according to any one of embodiments 1 to 99, wherein the main body portion includes a track on which the cap removal device is positioned to move axially relative to the main body portion, and the track is adapted such that the cap removal device is pressed against the track by the injection device when the injection device is positioned on the main body portion.

[0166] 101. The accessory according to Embodiment 100, wherein the track is fitted so that the cap removal device does not come out of the track when the injection device is positioned in the main body.

[0167] 102. The accessory according to Embodiment 100 or Embodiment 101, wherein the track is adapted so that the cap removal device is movable in a direction having components perpendicular to the axial direction when the injection device is not positioned in the main body portion.

[0168] 103. The accessory according to any one of embodiments 100 to 102, wherein the track is adapted such that when the injection device is positioned on the main body, the cap removal device is pressed against the track by the injection device, and as a result, the cap removal device can move only axially relative to the main body.

[0169] 104. The accessory according to any one of embodiments 1 to 103, wherein the main body portion comprises a track on which a cap removal device is positioned to slide.

[0170] 105. At least one cap removal device cam is arranged to slide within a slot in a body portion housing the surface of the cap removal device cam, as described in Embodiments 1 and 29, and optionally any one of Embodiments 2 to 28 and Embodiments 30 to 104.

[0171] 106. A system for administering an injection, the system comprising an injection device having a needle cap and an accessory as described in any one of embodiments 1 to 105.

[0172] 107. The injection device is Antibodies (monoclonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, silkumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab, or biosimilar bars thereof) for the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency toxicity, pain, thrombosis, infections, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, or myelodysplasia, or for use in the expression of protective immunity. The system according to Embodiment 106, comprising a substance selected from the group consisting of John (etc.), etanercept, abatacept, anakinra, epoetin alfa, darbepoetin alfa, epoetin beta-methoxypolyethylene glycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control substances, infection control or elimination substances, peptides, proteins, human insulin or human insulin analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic agents, antihistamines, anti-inflammatory agents, corticosteroids, disease-modifying antirheumatic agents, erythropoietin, or vaccines.

[0173] 108. Using the system described in Embodiment 106, deliver the substance to a human subject for the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy, hay fever, inflammation, anemia, or myelodysplasia, or for use in the expression of protective immunity, an antibody (monoclonal antibody, ustekinumab, golimumab, infliximab, guselkumab, silkumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab pegol, sarilumab) Substances selected from the group consisting of (such as secukinumab, ixekizumab, or biosimilar versions thereof), etanercept, abatacept, anakinra, epoetin alfa, darbepoetin alfa, epoetin beta-methoxypolyethylene glycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control substances, infection control or elimination substances, peptides, proteins, human insulin or human insulin analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic drugs, antihistamines, anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, or vaccines.

[0174] 109. Using the system described in Embodiment 106, antibodies (monoclonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, silkumab, adalimumab, centrizumabrituximab, tocilizumab, centrizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab, or biosimilar versions thereof), etanercept, abatacept, anakinra, epoetin alfa, darbepoetin alfa, epoetin beta-methoxypolyethylene glycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control substances, infection control or elimination substances, peptides, etc., can be administered to human subjects. An injection device for the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy, hay fever, inflammation, anemia, or myelodysplasia, or for use in the expression of protective immunity, by delivery of a substance selected from the group consisting of proteins, human insulin or human insulin analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic drugs, antihistamines, anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, or vaccines.

Claims

1. An accessory for an injection device having a needle cap, wherein the accessory is A main body portion having a recess adapted for receiving the injection device, A cover connected to the main body portion around at least one pivot point, the cover being pivotable between an open position in which the recess is exposed and the injection device is received, and a closed position in which the recess is at least partially closed and the injection device is held in place by the main body portion, A cap removal device comprising a gripping portion adapted to hold the needle cap, wherein the cap removal device comprises a cap removal device that is movable relative to the main body portion, The aforementioned cover is A proximal end that is moved by the user and adapted to move the cover from the open position to the closed position, An accessory comprising: at least one distal extension extending distally from the at least one pivot portion, the distal end of which is operably connected to the cap removal device such that when the cover is moved from the open position to the closed position, the cap removal device and the gripping portion move toward the end of the accessory, thereby removing the needle cap at least partially from the injection device.

2. The at least one pivot part is, The main body portion has at least one opening, The accessory according to claim 1, comprising at least one protrusion within the cover, wherein the at least one protrusion is rotatable within the opening.

3. The accessory according to claim 1 or 2, wherein the cover comprises a proximal extension extending proximally away from the at least one pivot portion.

4. The accessory according to claim 3, wherein the distal extension is shorter than the proximal extension.

5. The accessory according to claim 1 or 2, wherein the distal end of the cover is provided with a cover cam disposed within the cap removal device slot of the cap removal device.

6. The accessory according to claim 5, wherein the rotation of the cover cam about a pivot axis causes the cover cam to act against the slot of the cap removal device in order to translate the cap removal device within the accessory.

7. The accessory according to claim 5, wherein the cover pivots from the open position to the closed position to move the cap removal device toward the distal end of the accessory, and is positioned to act on the cover cam opposite to the cap removal device slot.

8. The accessory according to claim 7, wherein the gripping portion is arranged to hold the needle cap while the cap removal device slot moves toward the distal end of the accessory, thereby at least partially removing the needle cap from the injection device.

9. The accessory according to claim 5, wherein the cover pivots from the closed position to the open position to move the cap removal device toward the proximal end of the accessory, and is positioned to act on the cover cam opposite to the cap removal device slot.

10. The accessory according to claim 1 or 2, wherein the cover is connected to the main body portion by a pair of pivot parts.

11. The accessory according to claim 10, wherein the cover comprises a pair of distal extensions that extend distally from each of the pair of pivots.

12. A system for administering an injection, the system comprising: an injection device having the needle cap; and the accessories described in claim 1 or claim 2.

13. The injection device is Antibodies (monoclonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, silkumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab, or biosimilars thereof) for the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infections, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, or myelodysplasia, or for use in the expression of protective immunity) The system according to claim 12, comprising a substance selected from the group consisting of (such as iodine), etanercept, abatacept, anakinra, epoetin alfa, darbepoetin alfa, epoetin beta-methoxypolyethylene glycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control substances, infection control or elimination substances, peptides, proteins, human insulin or human insulin analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic agents, antihistamines, anti-inflammatory agents, corticosteroids, disease-modifying antirheumatic agents, erythropoietin, or vaccines.

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