Colon organoid, method for its preparation, and method for its use.

JP7875662B2Active Publication Date: 2026-06-18CHILDRENS HOSPITAL MEDICAL CENT CINCINNATI
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
CHILDRENS HOSPITAL MEDICAL CENT CINCINNATI
Filing Date
2024-03-28
Publication Date
2026-06-18

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Abstract

To provide human colonic organoids in vitro, usable for determining the efficacy and / or toxicity of potential therapeutics for a disease selected from the group consisting of colitis, colon cancer, polyposis syndrome and / or irritable bowel syndrome.SOLUTION: The disclosure provides a human colonic organoid (HCO), where the human colonic organoid comprises epithelium and mesenchyme and expresses SATB2, MUC2 and / or MUC5B.SELECTED DRAWING: Figure 1A
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