Agents that enhance the expression of epidermal maturation factors, filaggrin (FLG) expression, ATP-binding cassette subfamily A member (ABCA12) expression, tight junction formation promoters, and stratum corneum intercellular lipid production promoters.

JP7920014B2Active Publication Date: 2026-09-14POLA CHEMICAL INDUSTRIES INC
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Patent Information

Application Number
JP2022179689
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Filing Date
2022-11-09
Publication Date
2026-09-14
Estimated Expiration
2042-11-09

AI Technical Summary

Benefits of technology

【0028】 本発明の表皮成熟因子の発現亢進剤は、皮膚の保湿機能、バリア機能の獲得等に関与する表皮成熟因子の発現を亢進させることができる。 より具体的には、本発明の表皮成熟因子発現亢進剤は、表皮におけるFLG、ABCA12、SMPD1、CLDN4及びELOVL4から選ばれる1又は2以上の表皮成熟因子の発現を亢進させることができる。

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Abstract

To provide a novel technique that can enhance the expression of epidermal maturation factors involved in acquiring skin moisturizing functions or barrier functions.SOLUTION: An epidermal maturation factor expression enhancer contains composite extract containing extract from plants belonging to the genus Simmondsia of the family Simmondsiaceae and plants belonging to the genus Syzygium of the family Myrtaceae and / or osteocalcin as an active ingredient.SELECTED DRAWING: None
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