Oral care compositions comprising isomalt encapsulated gas pellets

Abstract

Oral care composition comprising an isomalt encapsulated gas pellet in a base, as well as methods and uses thereof. The oral care composition comprises an isomalt encapsulated gas pellet in a base, wherein a gas encapsulated within the isomalt encapsulated gas pellet is encapsulated in the isomalt prior to administration of the composition in a mouth of a user and the isomalt encapsulated gas pellet dissolves after the composition is administered to the mouth of the user.

Description

ORAL CARE COMPOSITIONS COMPRISING ISOMALT ENCAPSULATED GAS PELLETSField of the Invention

[0001] The present invention generally relates to oral care compositions. More particularly, the present invention relates to oral care compositions and products comprising isomalt encapsulated gas pellets, as well as methods and uses thereof.Background of the Invention

[0002] The use of oral care compositions, such as toothpastes, are important for improving and / or maintaining the oral hygiene of an individual. Conventional oral care compositions provide agents, such as abrasives and antimicrobial compounds, which prevent and / or remove tartar and / or plaque from the teeth of the user. Moreover, the act of brushing teeth with a conventional toothbrush to provide an oral care composition to the teeth and / or gums provides a mechanical means to dislodge food and maintain aspects of oral hygiene, however, the brushing habits of the user plays a significant role in the extent to which such oral care compositions are effective at improving and / or maintaining oral hygiene.

[0003] The utility of an oral care composition to provide an improvement or maintenance of oral hygiene in an individual may be influenced, in part, by the length of time in which the user cleans their teeth with the oral care composition. For example, the American Dental Association (ADA) recommends a user brushes their teeth twice per day for a minimum of two minutes.

[0004] It is common for the duration of the cleaning of a user’s teeth to be monitored using, for example, a timer provided on, for example, a toothbrush. The inclusion of such timing feature in a toothbrush requires the further addition of elements such as a battery to provide the necessary energy to power the timer. The requirement of a battery powered toothbrush to regulate the duration of brushing is limited in that it requires said toothbrush to have sufficient energy to perform the timing which requires either a power source (i.e. for charging) or batteries, both of which have significant limitations such as the need for a power source for charging or the cost of purchasing batteries and the environment impact of disposal of such batteries. Additionally, another device, such as a clock or timing device, may be used to regulate the length of brushing, however, this requires an additional consideration before, during and after application of an oral care composition. The ability to provide a means of timing a duration of brushing, such as an intrinsic timer provided in an element that is part of the users normal oral hygiene routine, without the need for a powered brushing device or an external non-oral hygiene device would help to promote a desired brushing duration.

[0005] Therefore, a means of providing an intrinsic brushing timer for a desired duration of toothbrushing without the need for an electrically powered device or additional device is required.Summary of the Invention

[0006] In an embodiment herein, there is provided an oral care composition comprising an isomalt encapsulated gas pellet in a base, wherein a gas encapsulated within the isomalt encapsulated gas pellet is encapsulated in the isomalt prior to administration of the composition in a mouth of a user and the isomalt encapsulated gas pellet dissolves after the composition is administered to the mouth of the user.

[0007] In certain embodiments, the isomalt encapsulated gas pellet may comprise a plurality of isomalt encapsulated gas pellets.

[0008] In certain embodiments, a portion of the gas encapsulated by the isomalt may be contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 1 minute, or at least 2 minutes following administration to the mouth of the user.

[0009] In certain embodiments, a portion of the gas encapsulated by the isomalt encapsulated gas pellet may be contained in the isomalt encapsulated gas pellet for about 2 minutes to about 3 minutes following administration to the mouth of the user.

[0010] In certain embodiments, substantially all of the gas encapsulated by the isomalt encapsulated gas pellet may be contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 1 minute or at least 2 minutes following administration to the mouth of the user.

[0011] In certain embodiments, substantially all of the gas encapsulated by the isomalt encapsulated gas pellet may be contained in the isomalt encapsulated gas pellet for about 2 minutes to about 3 minutes following administration to the mouth of the user.

[0012] In certain embodiments, the isomalt encapsulated pellet may dissolve within at least 1 minute, at least 2 minutes or at least 3 minutes after administration to the mouth of the user.

[0013] In certain embodiments, the isomalt encapsulated pellet may dissolve in about 2 minutes to about 3 minutes after administration to the mouth of the user.

[0014] In certain embodiments, the gas encapsulated by the isomalt may be carbon dioxide.

[0015] In certain embodiments, the isomalt encapsulated gas pellet may have an average size of between 2 mm and 5 mm.

[0016] In certain embodiments, the isomalt encapsulated gas pellet may have an average size of about 4 mm.

[0017] In certain embodiments, the isomalt encapsulated gas pellet may comprise 15 % to 25 % w / w of the composition.

[0018] In certain embodiments, the isomalt encapsulated gas pellet may comprise about 20 % w / w of the composition.

[0019] In certain embodiments, the base may comprise one or more surfactant, one or more silica, one or more flavoring agent, one or more oil, one or more additional agents or any combination thereof.

[0020] In certain embodiments, the base may be substantially free of water.

[0021] In certain embodiments, the base may comprise less than about 2%, less than about 1 .95%, less than about 1.9%, less than about 1 .85%, less than about 1 .8%, less than about 1 .75%, less than about 1.7%, less than about 1.65%, less than about 1.6%, less than about 1.55%, less than about 1.5%, less than about 1.45%, less than about 1.4%, less than about 1.35%, less than about 1.3%, less than about 1.25%, less than about 1.2%, less than about 1.15%, less than about 1.1 %, less than about 1.05%, less than about 1 %, less than about 0.95%, less than about 0.9%, less than about 0.85%, less than about 0.8%, less than about 0.75%, less than about 0.7%, less than about 0.65%, less than about 0.6%, less than about 0.55%, less than about 0.5%, less than about 0.45%, less than about 0.4%, less than about 0.35%, less than about 0.3%, less than about 0.25%, less than about 0.2%, less than about 0.15%, less than about 0.1 % or less than about 0.05% water.

[0022] In certain embodiments, the one or more silica may comprise hydrated silica, silicon dioxide, or any combination thereof.

[0023] In certain embodiments, the one or more flavoring agent may comprise xylitol, menthol, sorbitol, erythritol, Mentha Piperita oil, Mentha Viridis leaf oil, Siraitia Grosvenorii fruit extract, rebaudioside A, maltodextrin, carvone, limonene, hydrolyzed Gardenia Florida extract, sodium saccharin, glycyrrhizic acid, gamma-terpinene or any combination thereof.

[0024] In certain embodiments, the one or more fat or oil may comprise caprylic triglyceride, PEG-40 hydrogenated castor oil or any combination thereof.

[0025] In certain embodiments, the one or more surfactant may comprise sodium lauroyl sarcosinate, sodium lauryl sulfate, sodium alkylsulfo succinate, sodium cocomonoglyceride sulfonate, sucrose fatty acid esters or any combination thereof.

[0026] In certain embodiments, the one or more additional agent may comprise sodium bicarbonate, xanthan gum, calcium hydroxyapatite, zinc citrate, potassium citrate, stannous fluoride, potassium bitartrate, sodium benzoate, denatured alcohol, sodium chloride, water or any combination thereof.

[0027] In certain embodiments, the zinc citrate may be zinc citrate dihydrate.

[0028] In certain embodiments, the composition may further comprise a pigment or coloring agent.

[0029] In certain embodiments, the pigment or coloring agent may be titanium dioxide.

[0030] In certain embodiments there is provided herein, a composition comprising: caprylic triglyceride, isomalt, hydrated silica, xylitol, sodium bicarbonate, sorbitol, erythritol, sodium lauroyl sarcosinate, aroma, flavor, menthol, xanthan gum, PEG-40 hydrogenated castor oil, zinc citrate, Mentha Piperita oil, Mentha Viridis leaf oil, potassium citrate, stannous fluoride, Siraitia Grosvenorii fruit extract, sodium saccharin, potassium bitartrate, carbon dioxide, sodium benzoate, rebaudioside A, maltodextrin, carvone, denatured alcohol, limonene, sodium chloride, hydrolyzed Gardenia Florida extract, glycyrrhizic acid, gamma-terpinene, and water.

[0031] In certain embodiments there is provided herein, a composition comprising: caprylic triglyceride, isomalt, hydrated silica, xylitol, sodium bicarbonate, sorbitol, erythritol, sodium lauroyl sarcosinate, aroma, flavor, menthol, xanthan gum, PEG-40 hydrogenated castor oil, zinc citrate, Mentha Piperita oil, Mentha Viridis leaf oil, potassium citrate, stannous fluoride, Siraitia Grosvenorii fruit extract, sodium saccharin, potassium bitartrate, carbon dioxide, sodium benzoate, rebaudioside A, maltodextrin, carvone, denatured alcohol, limonene, sodium chloride, hydrolyzed Gardenia Florida extract, glycyrrhizic acid, gamma-terpinene, titanium dioxide and water.

[0032] In certain embodiments there is provided herein, a composition comprising: 10.00%- 50.00% caprylic triglyceride, 10.00%-30.00% isomalt, 5.00%-20.00% hydrated silica, 5.00%-20.00% xylitol, 1.00%-5.00% sodium bicarbonate, 1.00%-10.00% sorbitol, 1.00%-5.00% calcium hydroxyapatite, 1.00%-5.00% erythritol, 1.00%-5.00% sodium lauroyl sarcosinate, 1.00%-3.00% aroma / flavor, 1.00%-3.00% menthol, 1.00%-3.00% xanthan gum, 0.10%-2.00% PEG-40 hydrogenated castor oil, 0.10%-2.00% zinc citrate, 0.10%-2.00% Mentha Piperita oil, 0.10%-2.00% Mentha Viridis leafoil, 0.10%-2.00% potassium citrate, 0.10%-2.00% Siraitia Grosvenor / / fruit extract, 0.10%-2.00% sodium saccharin, 0.10%-2.00% potassium bitartrate, 0.01 %-1.00% carbon dioxide, 0.01 %-1.00% sodium benzoate, 0.01 %-1.00% rebaudioside A, 0.01%-1.00% maltodextrin, 0.01 %-1.00% carvone, 0.01 %- 1.00% denatured alcohol, 0.01 %-1.00% limonene, 0.01 %-1.0% sodium chloride, 0.001 %-0.01 % hydrolyzed Gardenia Florida extract, 0.001 %-0.01% glycyrrhizic acid, 0.0001 %-0.01 % gammaterpinene, and 0.01 %-1.00% water.

[0033] In certain embodiments there is provided herein, a composition comprising: 10.00%- 50.00% caprylic triglyceride, 10.00%-30.00% isomalt, 5.00%-20.00% hydrated silica, 5.00%-20.00% xylitol, 1.00%-5.00% sodium bicarbonate, 1.00%-10.00% sorbitol, 1.00%-5.00% calcium hydroxyapatite, 1.00%-5.00% erythritol, 1.00%-5.00% sodium lauroyl sarcosinate, 1.00%-3.00% aroma / flavor, 1.00%-3.00% menthol, 1.00%-3.00% xanthan gum, 0.10%-2.00% PEG-40 hydrogenated castor oil, 0.10%-2.00% zinc citrate, 0.10%-2.00% Mentha Piperita oil, 0.10%-2.00% Mentha Viridis leaf oil, 0.10%-2.00% potassium citrate, 0.10%-2.00% Siraitia Grosvenor / / fruit extract, 0.10%-2.00% sodium saccharin, 0.10%-2.00% potassium bitartrate, 0.01 %-1.00% carbon dioxide, 0.01 %-1.00% sodium benzoate, 0.01 %-1.00% rebaudioside A, 0.01%-1.00% maltodextrin, 0.01 %-1.00% carvone, 0.01 %- 1.00% denatured alcohol, 0.01 %-1.00% limonene, 0.01 %-1.0% sodium chloride, 0.001 %-0.01 % hydrolyzed Gardenia Florida extract, 0.001 %-0.01% glycyrrhizic acid, 0.0001 %-0.01 % gammaterpinene, 0.01%-1.00% water and titanium dioxide.

[0034] In certain embodiments, the base may be a toothpaste, gel, lozenge, chewing gum, or tablet.

[0035] In certain embodiments there is provided herein, a composition as disclosed herein for regulating a duration of cleaning of a user’s teeth and / or gums.

[0036] In certain embodiments there is provided herein, uses of a composition as disclosed herein for regulating a duration of cleaning of a user’s teeth and / or gums.

[0037] In certain embodiments there is provided herein, methods of cleaning a user's teeth and / or gums, the method comprising the steps of applying a composition of the present disclosure to the mouth of the user; and brushing with a brush, teeth of the user with the composition until substantially all of the isomalt encapsulated gas pellet has dissolved.

[0038] In certain embodiments, the methods or uses may further comprise, a step of applying the composition to the brush before the step of applying the composition to the mouth of the user.

[0039] In certain embodiments, substantially all of the isomalt encapsulated gas pellet may have dissolved when the composition ceases popping in the mouth of the user.Detailed Description

[0040] Described herein are oral care compositions, products comprising oral care compositions, and methods and uses thereof. It will be appreciated that embodiments and examples are provided herein for illustrative purposes intended for those skilled in the art, and are not meant to be limiting in any way.

[0041] As used herein, an “oral care composition” means a composition for use in the oral cavity for a time sufficient to contact some or all of the dental surfaces and / or oral tissues for purposes of oral cleaning and / or hygiene. The oral care composition of the present invention may be in various forms including toothpaste, dentifrice, tooth gel, tooth powders, tablets, rinse, sub gingival gel, foam, or chewing gum. In certain embodiments, all of the components of the composition may be food grade or appropriate for use in an oral care composition, as deemed appropriate by local regulations.

[0042] As used herein, the term “teeth” or “tooth” may refer to both a natural tooth or teeth of a user or synthetic teeth as would be known to the person of skill, such as, for example, dentures. In certain embodiments, the synthetic teeth may be made of any material known to the skilled person. As used herein, the term “dental surface” may refer to the surface of a tooth or the surfaces of teeth.

[0043] As used herein, the term “brushing”, “brush” or “brushed” may comprise the act of contacting and / or cleaning the mouth, teeth, gums or any combination thereof. In certain embodiments, “brushing” may improve and / or maintain the oral hygiene of the user. In certain embodiments, “brushing” may comprise contacting one or more dental surface or one or more portion of the oral cavity with the composition. In certain embodiments, “brushing” may comprise the use of a tool, such as toothbrush, to contact one or more dental surface or one or more portion of the oral cavity. In certain embodiments, the toothbrush may comprise any brush known to the skilled person to be appropriate for use as such. In certain embodiments, the toothbrush may not be a powered device i.e. the device does not require a battery or power to operate. In a preferred embodiment, the toothbrush does not provide a timer or timing device therein.

[0044] In certain embodiments, there is provided herein an oral care composition comprising an isomalt encapsulated gas pellet in a base, wherein a gas encapsulated within the isomalt encapsulatedgas pellet is encapsulated in the isomalt prior to administration of the composition in a mouth of a user and the isomalt encapsulated gas pellet dissolves after the composition is administered to the mouth of the user. It is contemplated that the gas encapsulated within the isomalt encapsulated gas pellet is encapsulated in the isomalt and is substantially stable therein for extended periods of time. In certain embodiments, the isomalt encapsulated gas pellets are stable in the base prior to administration to the mouth of a user for at least at least 1 month, at least 2 month, at least 3 month, at least 4 month, at least 5 month, at least 6 month, at least 7 month, at least 8 month, at least 9 month, at least 10 month, at least 11 month, at least 12 month, at least 13 month, at least 14 month, at least 15 month, at least 16 month, at least 17 month, at least 18 month, at least 19 month, at least 20 month, at least 21 month, at least 22 month, at least 23 month, at least 24 month, at least 25 month, at least 26 month, at least 27 month, at least 28 month, at least 29 month, at least 30 month, at least 31 month, at least 32 month, at least 33 month, at least 34 month, at least 35 month, at least 36 month. In certain embodiments, the isomalt encapsulated gas pellets are stable in the base prior to administration to the mouth of a user at room temperature, shipping temperature, storage temperature or any combination thereof.

[0045] As used herein, the expression “an isomalt encapsulated gas pellet” may refer to a gas that is contained within a pellet, wherein the pellet is formed substantially of isomalt. Isomalt, as used herein, may refer to a mixture of 1-O-a-D-glucopyranosido-D-mannitol (1 ,1-GPM) and 6-O-a-D- glucopyranosido-D-sorbitol (1 ,6-GPS). In certain embodiments, the isomalt may form a shell with a cavity therein, wherein in said cavity a gas is contained. In certain embodiments, the gas encapsulated by the isomalt pellet is retained therein in the composition. The term pellet, as used herein, may refer to a solid of varying shape. In certain embodiments, the isomalt encapsulated gas pellet may be any shape wherein said gas is retained therein. In certain embodiments, the release of gas from the isomalt encapsulated gas pellet may comprise a physical or auditory stimulus in the mouth of the user. In certain embodiments, the release of gas from the isomalt encapsulated gas pellet may comprise a popping sensation and / or popping sound in the mouth of the user. In certain embodiments, the isomalt encapsulated gas pellet may comprise Pop Rocks® or another gasified candy comprising an isomalt encapsulating gas pellet.

[0046] In certain embodiments, the oral care composition comprises a base, wherein an isomalt encapsulated gas pellet is comprised within the base. In certain embodiments, the base may meet local requirements and / or regulatory approval for the sale and usage therein as an oral care product. In certain embodiments, the base may be substantially anhydrous. As contemplated herein, the base may be a toothpaste, gel, lozenge, chewing gum, or tablet.

[0047] In certain embodiments, the composition may comprise a gas encapsulated within an isomalt encapsulated gas pellet. In certain embodiments, the gas may comprise carbon dioxide. In certain embodiments, the gas may comprise any gas wherein its release from the isomalt encapsulated pellet provides a physical and / or auditory stimulus to the user to indicate the dissolving of the pellet and release of the gas therefrom. In certain embodiments, a physical and / or auditory stimulus may comprise popping. In certain embodiments, the gas is encapsulated in the isomalt prior to administration of the composition in a mouth of a user. As used herein, the gas encapsulated in the isomalt prior to administration may comprise the composition in a container, such as a container for sale including, for example, a tube, and / or the composition prior to contacting the mouth of the user, such as for example, after administration to a toothbrush..

[0048] In certain embodiments, the isomalt encapsulating the gas dissolves after the composition is administered to the mouth of the user. In certain embodiments, dissolves may refer to the breakdown of the isomalt such that the gas encapsulated therein is released from the pellet. In certain embodiments, dissolves may refer to the solubulization of the isomalt in the mouth of the user. In certain embodiments, the dissolving may comprise a physical and / or auditory stimulus to the user, such as, for example, popping.

[0049] In certain embodiments, the isomalt encapsulated gas pellet may comprise a plurality of isomalt encapsulated gas pellets. In certain embodiments, the plurality of isomalt encapsulated gas pellets may have an average size of 2 mm, 2.01 mm, 2.02 mm, 2.03 mm, 2.04 mm, 2.05 mm, 2.06 mm, 2.07 mm, 2.08 mm, 2.09 mm, 2.1 mm, 2.11 mm, 2.12 mm, 2.13 mm, 2.14 mm, 2.15 mm, 2.16 mm, 2.17 mm, 2.18 mm, 2.19 mm, 2.2 mm, 2.21 mm, 2.22 mm, 2.23 mm, 2.24 mm, 2.25 mm, 2.26 mm, 2.27 mm, 2.28 mm, 2.29 mm, 2.3 mm, 2.31 mm, 2.32 mm, 2.33 mm, 2.34 mm, 2.35 mm, 2.36 mm, 2.37 mm, 2.38 mm, 2.39 mm, 2.4 mm, 2.41 mm, 2.42 mm, 2.43 mm, 2.44 mm, 2.45 mm, 2.46 mm, 2.47 mm, 2.48 mm,2.49 mm, 2.5 mm, 2.51 mm, 2.52 mm, 2.53 mm, 2.54 mm, 2.55 mm, 2.56 mm, 2.57 mm, 2.58 mm, 2.59 mm, 2.6 mm, 2.61 mm, 2.62 mm, 2.63 mm, 2.64 mm, 2.65 mm, 2.66 mm, 2.67 mm, 2.68 mm, 2.69 mm,2.7 mm, 2.71 mm, 2.72 mm, 2.73 mm, 2.74 mm, 2.75 mm, 2.76 mm, 2.77 mm, 2.78 mm, 2.79 mm, 2.8 mm, 2.81 mm, 2.82 mm, 2.83 mm, 2.84 mm, 2.85 mm, 2.86 mm, 2.87 mm, 2.88 mm, 2.89 mm, 2.9 mm,2.91 mm, 2.92 mm, 2.93 mm, 2.94 mm, 2.95 mm, 2.96 mm, 2.97 mm, 2.98 mm, 2.99 mm, 3 mm, 3.01 mm, 3.02 mm, 3.03 mm, 3.04 mm, 3.05 mm, 3.06 mm, 3.07 mm, 3.08 mm, 3.09 mm, 3.1 mm, 3.11 mm,3.12 mm, 3.13 mm, 3.14 mm, 3.15 mm, 3.16 mm, 3.17 mm, 3.18 mm, 3.19 mm, 3.2 mm, 3.21 mm, 3.22 mm, 3.23 mm, 3.24 mm, 3.25 mm, 3.26 mm, 3.27 mm, 3.28 mm, 3.29 mm, 3.3 mm, 3.31 mm, 3.32 mm,3.33 mm, 3.34 mm, 3.35 mm, 3.36 mm, 3.37 mm, 3.38 mm, 3.39 mm, 3.4 mm, 3.41 mm, 3.42 mm, 3.43 mm, 3.44 mm, 3.45 mm, 3.46 mm, 3.47 mm, 3.48 mm, 3.49 mm, 3.5 mm, 3.51 mm, 3.52 mm, 3.53 mm,3.54 mm, 3.55 mm, 3.56 mm, 3.57 mm, 3.58 mm, 3.59 mm, 3.6 mm, 3.61 mm, 3.62 mm, 3.63 mm, 3.64mm, 3.65 mm, 3.66 mm, 3.67 mm, 3.68 mm, 3.69 mm, 3.7 mm, 3.71 mm, 3.72 mm, 3.73 mm, 3.74 mm, 3.75 mm, 3.76 mm, 3.77 mm, 3.78 mm, 3.79 mm, 3.8 mm, 3.81 mm, 3.82 mm, 3.83 mm, 3.84 mm, 3.85 mm, 3.86 mm, 3.87 mm, 3.88 mm, 3.89 mm, 3.9 mm, 3.91 mm, 3.92 mm, 3.93 mm, 3.94 mm, 3.95 mm, 3.96 mm, 3.97 mm, 3.98 mm, 3.99 mm, 4 mm, 4.01 mm, 4.02 mm, 4.03 mm, 4.04 mm, 4.05 mm, 4.06 mm, 4.07 mm, 4.08 mm, 4.09 mm, 4.1 mm, 4.11 mm, 4.12 mm, 4.13 mm, 4.14 mm, 4.15 mm, 4.16 mm, 4.17 mm, 4.18 mm, 4.19 mm, 4.2 mm, 4.21 mm, 4.22 mm, 4.23 mm, 4.24 mm, 4.25 mm, 4.26 mm, 4.27 mm, 4.28 mm, 4.29 mm, 4.3 mm, 4.31 mm, 4.32 mm, 4.33 mm, 4.34 mm, 4.35 mm, 4.36 mm, 4.37 mm, 4.38 mm, 4.39 mm, 4.4 mm, 4.41 mm, 4.42 mm, 4.43 mm, 4.44 mm, 4.45 mm, 4.46 mm, 4.47 mm, 4.48 mm, 4.49 mm, 4.5 mm, 4.51 mm, 4.52 mm, 4.53 mm, 4.54 mm, 4.55 mm, 4.56 mm, 4.57 mm, 4.58 mm,4.59 mm, 4.6 mm, 4.61 mm, 4.62 mm, 4.63 mm, 4.64 mm, 4.65 mm, 4.66 mm, 4.67 mm, 4.68 mm, 4.69 mm, 4.7 mm, 4.71 mm, 4.72 mm, 4.73 mm, 4.74 mm, 4.75 mm, 4.76 mm, 4.77 mm, 4.78 mm, 4.79 mm,4.8 mm, 4.81 mm, 4.82 mm, 4.83 mm, 4.84 mm, 4.85 mm, 4.86 mm, 4.87 mm, 4.88 mm, 4.89 mm, 4.9 mm, 4.91 mm, 4.92 mm, 4.93 mm, 4.94 mm, 4.95 mm, 4.96 mm, 4.97 mm, 4.98 mm, 4.99 mm, or 5 mm.

[0050] In certain embodiments, a portion of the gas encapsulated by the isomalt may be contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 1 minute, or at least 2 minutes following administration to the mouth of the user. Contained in the isomalt encapsulated gas pellet, as used herein, may refer to the presence of the gas within the isomalt encapsulated gas pellet, such that “contained” refers to presence of the gas therein. In certain embodiments, the gas contained in the isomalt encapsulated gas pellet may refer to the gas contained in a plurality of isomalt encapsulated gas pellets, and the portion of gas encapsulated by the plurality of isomalt containing gas pellets may refer to a portion of the total amount of pellets, a single pellet containing a portion of the total amount of gas originally present in the single pellet, or any combination thereof. In certain embodiments, a portion of the gas encapsulated by the isomalt may be contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 31 seconds, at least 32 seconds, at least 33 seconds, at least 34 seconds, at least 35 seconds, at least 36 seconds, at least 37 seconds, at least 38 seconds, at least 39 seconds, at least 40 seconds, at least 41 seconds, at least 42 seconds, at least 43 seconds, at least 44 seconds, at least 45 seconds, at least 46 seconds, at least 47 seconds, at least 48 seconds, at least 49 seconds, at least 50 seconds, at least 51 seconds, at least 52 seconds, at least 53 seconds, at least 54 seconds, at least 55 seconds, at least 56 seconds, at least 57 seconds, at least 58 seconds, at least 59 seconds, at least 60 seconds, at least 61 seconds, at least 62 seconds, at least 63 seconds, at least 64 seconds, at least 65 seconds, at least 66 seconds, at least 67 seconds, at least 68 seconds, at least 69 seconds, at least 70 seconds, at least 71 seconds, at least 72 seconds, at least 73 seconds, at least 74 seconds, at least 75 seconds, at least 76 seconds, at least 77 seconds, at least 78 seconds, at least 79 seconds, at least 80 seconds, at least 81 seconds, at least 82 seconds, at least 83seconds, at least 84 seconds, at least 85 seconds, at least 86 seconds, at least 87 seconds, at least 88 seconds, at least 89 seconds, at least 90 seconds, at least 91 seconds, at least 92 seconds, at least 93 seconds, at least 94 seconds, at least 95 seconds, at least 96 seconds, at least 97 seconds, at least 98 seconds, at least 99 seconds, at least 100 seconds, at least 101 seconds, at least 102 seconds, at least103 seconds, at least 104 seconds, at least 105 seconds, at least 106 seconds, at least 107 seconds, at least 108 seconds, at least 109 seconds, at least 110 seconds, at least 111 seconds, at least 112 seconds, at least 113 seconds, at least 114 seconds, at least 115 seconds, at least 116 seconds, at least 117 seconds, at least 118 seconds, at least 119 seconds, or at least 120 seconds following administration to the mouth of the user. In certain embodiments, the gas contained within the isomalt encapsulated gas pellet may be reduced from that present in the composition prior to administration to the mouth of the user. In certain embodiments, a portion of the gas encapsulated by the isomalt may be contained in the isomalt encapsulated gas pellet for about 2 minutes to about 3 minutes following administration to the mouth of the user.

[0051] In certain embodiments, substantially all of the gas encapsulated by the isomalt encapsulated gas pellet is contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 1 minute or at least 2 minutes following administration to the mouth of the user. In certain embodiments, substantially all of the gas encapsulated by the isomalt encapsulated gas pellet is contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 31 seconds, at least 32 seconds, at least 33 seconds, at least 34 seconds, at least 35 seconds, at least 36 seconds, at least37 seconds, at least 38 seconds, at least 39 seconds, at least 40 seconds, at least 41 seconds, at least42 seconds, at least 43 seconds, at least 44 seconds, at least 45 seconds, at least 46 seconds, at least47 seconds, at least 48 seconds, at least 49 seconds, at least 50 seconds, at least 51 seconds, at least52 seconds, at least 53 seconds, at least 54 seconds, at least 55 seconds, at least 56 seconds, at least57 seconds, at least 58 seconds, at least 59 seconds, at least 60 seconds, at least 61 seconds, at least62 seconds, at least 63 seconds, at least 64 seconds, at least 65 seconds, at least 66 seconds, at least67 seconds, at least 68 seconds, at least 69 seconds, at least 70 seconds, at least 71 seconds, at least72 seconds, at least 73 seconds, at least 74 seconds, at least 75 seconds, at least 76 seconds, at least77 seconds, at least 78 seconds, at least 79 seconds, at least 80 seconds, at least 81 seconds, at least82 seconds, at least 83 seconds, at least 84 seconds, at least 85 seconds, at least 86 seconds, at least87 seconds, at least 88 seconds, at least 89 seconds, at least 90 seconds, at least 91 seconds, at least92 seconds, at least 93 seconds, at least 94 seconds, at least 95 seconds, at least 96 seconds, at least97 seconds, at least 98 seconds, at least 99 seconds, at least 100 seconds, at least 101 seconds, at least 102 seconds, at least 103 seconds, at least 104 seconds, at least 105 seconds, at least 106 seconds, at least 107 seconds, at least 108 seconds, at least 109 seconds, at least 110 seconds, at least 111 seconds, at least 112 seconds, at least 113 seconds, at least 114 seconds, at least 115seconds, at least 116 seconds, at least 117 seconds, at least 118 seconds, at least 119 seconds, or at least 120 seconds following administration to the mouth of the user. In certain embodiments, substantially all of the gas encapsulated by the isomalt encapsulated gas pellet is contained in the isomalt encapsulated gas pellet for about 2 minutes to about 3 minutes following administration to the mouth of the user.

[0052] In certain embodiments, the plurality of isomalt encapsulated pellets may dissolve after administration to the mouth of the user within at least 2 minutes or at least 3 minutes. In certain embodiments, the plurality of isomalt encapsulated pellets may dissolve after administration to the mouth of the user within at least 100 seconds, at least 101 seconds, at least 102 seconds, at least 103 seconds, at least 104 seconds, at least 105 seconds, at least 106 seconds, at least 107 seconds, at least 108 seconds, at least 109 seconds, at least 110 seconds, at least 111 seconds, at least 112 seconds, at least 113 seconds, at least 114 seconds, at least 115 seconds, at least 116 seconds, at least 117 seconds, at least 118 seconds, at least 119 seconds, at least 120 seconds, at least 121 seconds, at least 122 seconds, at least 123 seconds, at least 124 seconds, at least 125 seconds, at least 126 seconds, at least 127 seconds, at least 128 seconds, at least 129 seconds, at least 130 seconds, at least 131 seconds, at least 132 seconds, at least 133 seconds, at least 134 seconds, at least 135 seconds, at least 136 seconds, at least 137 seconds, at least 138 seconds, at least 139 seconds, at least 140 seconds, at least 141 seconds, at least 142 seconds, at least 143 seconds, at least 144 seconds, at least 145 seconds, at least 146 seconds, at least 147 seconds, at least 148 seconds, at least 149 seconds, at least 150 seconds, at least 151 seconds, at least 152 seconds, at least 153 seconds, at least 154 seconds, at least 155 seconds, at least 156 seconds, at least 157 seconds, at least 158 seconds, at least 159 seconds, at least 160 seconds, at least 161 seconds, at least 162 seconds, at least 163 seconds, at least 164 seconds, at least 165 seconds, at least 166 seconds, at least 167 seconds, at least 168 seconds, at least 169 seconds, at least 170 seconds, at least 171 seconds, at least 172 seconds, at least 173 seconds, at least 174 seconds, at least 175 seconds, at least 176 seconds, at least 177 seconds, at least 178 seconds, at least 179 seconds, or at least 180 seconds. In certain embodiments, the plurality of isomalt encapsulated pellet may dissolve after administration to the mouth of the user within about 2 minutes to about 3 minutes.

[0053] In certain embodiments, the isomalt encapsulated gas pellet may have a size of between 2 mm and 5 mm. In certain embodiments, the isomalt encapsulated gas pellet may have a size of 2 mm, 2.01 mm, 2.02 mm, 2.03 mm, 2.04 mm, 2.05 mm, 2.06 mm, 2.07 mm, 2.08 mm, 2.09 mm, 2.1 mm, 2.11 mm, 2.12 mm, 2.13 mm, 2.14 mm, 2.15 mm, 2.16 mm, 2.17 mm, 2.18 mm, 2.19 mm, 2.2 mm, 2.21 mm, 2.22 mm, 2.23 mm, 2.24 mm, 2.25 mm, 2.26 mm, 2.27 mm, 2.28 mm, 2.29 mm, 2.3 mm, 2.31 mm, 2.32 mm, 2.33 mm, 2.34 mm, 2.35 mm, 2.36 mm, 2.37 mm, 2.38 mm, 2.39 mm, 2.4 mm, 2.41 mm, 2.42 mm,2.43 mm, 2.44 mm, 2.45 mm, 2.46 mm, 2.47 mm, 2.48 mm, 2.49 mm, 2.5 mm, 2.51 mm, 2.52 mm, 2.53 mm, 2.54 mm, 2.55 mm, 2.56 mm, 2.57 mm, 2.58 mm, 2.59 mm, 2.6 mm, 2.61 mm, 2.62 mm, 2.63 mm,2.64 mm, 2.65 mm, 2.66 mm, 2.67 mm, 2.68 mm, 2.69 mm, 2.7 mm, 2.71 mm, 2.72 mm, 2.73 mm, 2.74 mm, 2.75 mm, 2.76 mm, 2.77 mm, 2.78 mm, 2.79 mm, 2.8 mm, 2.81 mm, 2.82 mm, 2.83 mm, 2.84 mm,2.85 mm, 2.86 mm, 2.87 mm, 2.88 mm, 2.89 mm, 2.9 mm, 2.91 mm, 2.92 mm, 2.93 mm, 2.94 mm, 2.95 mm, 2.96 mm, 2.97 mm, 2.98 mm, 2.99 mm, 3 mm, 3.01 mm, 3.02 mm, 3.03 mm, 3.04 mm, 3.05 mm, 3.06 mm, 3.07 mm, 3.08 mm, 3.09 mm, 3.1 mm, 3.11 mm, 3.12 mm, 3.13 mm, 3.14 mm, 3.15 mm, 3.16 mm, 3.17 mm, 3.18 mm, 3.19 mm, 3.2 mm, 3.21 mm, 3.22 mm, 3.23 mm, 3.24 mm, 3.25 mm, 3.26 mm,3.27 mm, 3.28 mm, 3.29 mm, 3.3 mm, 3.31 mm, 3.32 mm, 3.33 mm, 3.34 mm, 3.35 mm, 3.36 mm, 3.37 mm, 3.38 mm, 3.39 mm, 3.4 mm, 3.41 mm, 3.42 mm, 3.43 mm, 3.44 mm, 3.45 mm, 3.46 mm, 3.47 mm,3.48 mm, 3.49 mm, 3.5 mm, 3.51 mm, 3.52 mm, 3.53 mm, 3.54 mm, 3.55 mm, 3.56 mm, 3.57 mm, 3.58 mm, 3.59 mm, 3.6 mm, 3.61 mm, 3.62 mm, 3.63 mm, 3.64 mm, 3.65 mm, 3.66 mm, 3.67 mm, 3.68 mm,3.69 mm, 3.7 mm, 3.71 mm, 3.72 mm, 3.73 mm, 3.74 mm, 3.75 mm, 3.76 mm, 3.77 mm, 3.78 mm, 3.79 mm, 3.8 mm, 3.81 mm, 3.82 mm, 3.83 mm, 3.84 mm, 3.85 mm, 3.86 mm, 3.87 mm, 3.88 mm, 3.89 mm,3.9 mm, 3.91 mm, 3.92 mm, 3.93 mm, 3.94 mm, 3.95 mm, 3.96 mm, 3.97 mm, 3.98 mm, 3.99 mm, 4 mm, 4.01 mm, 4.02 mm, 4.03 mm, 4.04 mm, 4.05 mm, 4.06 mm, 4.07 mm, 4.08 mm, 4.09 mm, 4.1 mm, 4.11 mm, 4.12 mm, 4.13 mm, 4.14 mm, 4.15 mm, 4.16 mm, 4.17 mm, 4.18 mm, 4.19 mm, 4.2 mm, 4.21 mm, 4.22 mm, 4.23 mm, 4.24 mm, 4.25 mm, 4.26 mm, 4.27 mm, 4.28 mm, 4.29 mm, 4.3 mm, 4.31 mm,4.32 mm, 4.33 mm, 4.34 mm, 4.35 mm, 4.36 mm, 4.37 mm, 4.38 mm, 4.39 mm, 4.4 mm, 4.41 mm, 4.42 mm, 4.43 mm, 4.44 mm, 4.45 mm, 4.46 mm, 4.47 mm, 4.48 mm, 4.49 mm, 4.5 mm, 4.51 mm, 4.52 mm,4.53 mm, 4.54 mm, 4.55 mm, 4.56 mm, 4.57 mm, 4.58 mm, 4.59 mm, 4.6 mm, 4.61 mm, 4.62 mm, 4.63 mm, 4.64 mm, 4.65 mm, 4.66 mm, 4.67 mm, 4.68 mm, 4.69 mm, 4.7 mm, 4.71 mm, 4.72 mm, 4.73 mm,4.74 mm, 4.75 mm, 4.76 mm, 4.77 mm, 4.78 mm, 4.79 mm, 4.8 mm, 4.81 mm, 4.82 mm, 4.83 mm, 4.84 mm, 4.85 mm, 4.86 mm, 4.87 mm, 4.88 mm, 4.89 mm, 4.9 mm, 4.91 mm, 4.92 mm, 4.93 mm, 4.94 mm,4.95 mm, 4.96 mm, 4.97 mm, 4.98 mm, 4.99 mm, or 5 mm. In certain embodiments, the isomalt encapsulated gas pellet may have a size of about 4 mm.

[0054] In certain embodiments, the isomalt encapsulated gas pellet may comprise about 15 % to about 25 % w / w of the composition. In certain embodiments, the isomalt encapsulated gas pellet may comprise 15 %, 15.1 %, 15.2 %, 15.3 %, 15.4 %, 15.5 %, 15.6 %, 15.7 %, 15.8 %, 15.9 %, 16 %, 16.1 %, 16.2 %, 16.3 %, 16.4 %, 16.5 %, 16.6 %, 16.7 %, 16.8 %, 16.9 %, 17 %, 17.1 %, 17.2 %, 17.3 %, 17.4 %, 17.5 %, 17.6 %, 17.7 %, 17.8 %, 17.9 %, 18 %, 18.1 %, 18.2 %, 18.3 %, 18.4 %, 18.5 %, 18.6 %, 18.7 %, 18.8 %, 18.9 %, 19 %, 19.1 %, 19.2 %, 19.3 %, 19.4 %, 19.5 %, 19.6 %, 19.7 %, 19.8 %,19.9 %, 20 %, 20.1 %, 20.2 %, 20.3 %, 20.4 %, 20.5 %, 20.6 %, 20.7 %, 20.8 %, 20.9 %, 21 %, 21.1 %,21.2 %, 21.3 %, 21.4 %, 21.5 %, 21.6 %, 21.7 %, 21.8 %, 21.9 %, 22 %, 22.1 %, 22.2 %, 22.3 %, 22.4%, 22.5 %, 22.6 %, 22.7 %, 22.8 %, 22.9 %, 23 %, 23.1 %, 23.2 %, 23.3 %, 23.4 %, 23.5 %, 23.6 %,23.7 %, 23.8 %, 23.9 %, 24 %, 24.1 %, 24.2 %, 24.3 %, 24.4 %, 24.5 %, 24.6 %, 24.7 %, 24.8 %, 24.9 %, or 25 % w / w of the composition. In certain embodiments, the isomalt encapsulated gas pellet may comprise about 20 % w / w of the composition. In certain embodiments, the proportion of the composition comprising the isomalt encapsulated gas pellet may be determined before, during or after preparation of the composition.

[0055] In certain embodiments, the composition may comprise one or more surfactant. In certain embodiments, the one or more surfactant may comprise sodium lauroyl sarcosinate, sodium lauryl sulfate, sodium alkylsulfo succinate, sodium cocomonoglyceride sulfonate and sucrose fatty acid esters. The skilled person, in light of the specification as a whole, would be able to select an appropriate one or more surfactant for inclusion in the composition.

[0056] In certain embodiments, the composition may comprise one or more silica. In certain embodiments, the one or more silica may comprise hydrated silica, silicon dioxide, or any combination thereof. As would be known to the person of skill, silica may be included in certain oral care compositions to provide an abrasive element to the composition for cleaning a surface, such as the dental surface, to which it is applied and brushed thereto. As would be known to the person of skill, an abrasive in an oral care composition may be used for abrading, grinding or polishing the teeth and / or gums of the user. Abrasives may remove substances that adhere to the surface of a tooth without scratching or damaging the tooth. The skilled person, in light of the specification as a whole, would be able to select an appropriate one or more silica for inclusion in the composition. In certain embodiments, the one or more silica may comprise an abrasive that does not comprise silica. In certain embodiments, the one or more silica may comprise calcium carbonate (CaCO3), calcium phosphate - dibasic, calcium phosphate - dibasic - hydrate, silica, silica hydrate, silicon dioxide, aluminum hydroxide, calcium pyrophosphate, insoluble sodium metaphosphate, magnesium carbonate, aluminum or any combination thereof.

[0057] In certain embodiments, the composition may comprise one or more flavoring agent. In certain embodiments, the one or more flavoring agent may comprise xylitol, menthol, sorbitol, erythritol, Mentha Piperita oil, Mentha Viridis leaf oil, Siraitia Grosvenor / / fruit extract, rebaudioside A, maltodextrin, carvone, limonene, hydrolyzed Gardenia Florida extract, sodium saccharin, glycyrrhizic acid, gammaterpinene, glycerol or any combination thereof. The skilled person, in light of the specification as a whole, would be able to select an appropriate one or more flavoring agent for inclusion in the composition. In certain embodiments, the one or more flavoring agent may be a natural flavoring agent or a synthetic flavoring agent. In certain embodiments, the one or more flavoring agent may comprise one or more oil.

[0058] In certain embodiments, the composition may comprise one or more oil. In certain embodiments, the one or more oil may comprise caprylic triglyceride, thymol, menthol, eucalyptol,methyl salicylate, PEG-40 hydrogenated castor oil, polyglyceryl-4 caprate or any combination thereof. The skilled person, in light of the specification as a whole, would be able to select an appropriate one or more oil for inclusion in the composition. In certain embodiments, the one or more oil may comprise one or more flavoring agent.

[0059] In certain embodiments, the composition may comprise one or more additional agents. In certain embodiments, the composition may comprise one or more of hydrophobic plasticizer, sodium bicarbonate, xanthan gum, calcium hydroxyapatite, carrageenan gum, sodium alginate, carbomers, zinc citrate, potassium citrate, fluoride, potassium bitartrate, sodium benzoate, methylparaben, ethylparaben, triclosan, stannous pyrophosphate, zinc chloride, denatured alcohol, sodium chloride, dimethicones, tetrasodium pyrophosphate, tetra-potassium pyrophosphate, disodium pyrophosphate water or any combination thereof. In certain embodiments, the hydrophobic plasticizer may comprise one or more of: acetyl tributyl citrate; acetyl triethyl citrate; castor oil: diacetylated monoglycerides: dibutyl sebacate: diethyl phthalate: triacetin; tributyl citrate; glycerol, polyethylene glycol, polyethylene glycol monomethyl ether, propylene glycol, sorbitol sorbitan and triethyl citrate In certain embodiments, the zinc citrate may be zinc citrate dihydrate. In certain embodiments, the one or more additional agent may comprise an agent or agents that reduce tooth sensitivity of the user, such as, but not limited to potassium salts. In certain embodiments, the one or more additional agent may comprise fluoride. In certain embodiments, the fluoride may comprise sodium fluoride, sodium monofluorophosphate, and / or stannous fluoride. In certain embodiments, the one or more additional agent may comprise one or more flavoring agent, one or more surfactant and / or one or more oil.

[0060] In certain embodiments, the composition may be is substantially free of water. In certain embodiments, the composition may be anhydrous. In certain embodiments, the base may comprise less than about 2%, less than about 1.95%, less than about 1.9%, less than about 1.85%, less than about 1.8%, less than about 1.75%, less than about 1.7%, less than about 1.65%, less than about 1.6%, less than about 1.55%, less than about 1.5%, less than about 1.45%, less than about 1.4%, less than about 1.35%, less than about 1.3%, less than about 1.25%, less than about 1.2%, less than about 1.15%, less than about 1.1%, less than about 1.05%, less than about 1%, less than about 0.95%, less than about 0.9%, less than about 0.85%, less than about 0.8%, less than about 0.75%, less than about 0.7%, less than about 0.65%, less than about 0.6%, less than about 0.55%, less than about 0.5%, less than about 0.45%, less than about 0.4%, less than about 0.35%, less than about 0.3%, less than about 0.25%, less than about 0.2%, less than about 0.15%, less than about 0.1 % or less than about 0.05% water. In certain embodiments, the composition may comprise a percentage water therein such that a gas encapsulated within the isomalt encapsulated gas pellet is encapsulated in the isomalt prior to administration of the composition in a mouth of a user. In certain embodiments, the composition may comprise a percentageof water such that a gas encapsulated within the isomalt encapsulated gas pellet is released after administration of the composition in a mouth of a user.

[0061] In certain embodiments, the composition further comprises a pigment or coloring agent. In certain embodiments, the pigment or coloring agent is titanium dioxide. The skilled person, in light of the specification as whole, would be able to select a desired pigment or coloring agent to obtain the composition and / or practice the method as disclosed herein.

[0062] In certain embodiments as described herein components of the composition may be referred to using names provided by the International Nomenclature of Cosmetic Ingredients (INCI), or any equivalent thereof. The skilled person, in light of the teachings herein, would be able to select the appropriate component using the INCI designation of the component or an equivalent thereof, such as for example, Cl 77891 may be referred to as such or as titanium dioxide or pigment white. Furthermore, the skilled person, in light of the teachings herein, would be able to select an appropriate commercial equivalent of said component, such as for example Creasperse® ID White R to provide Cl 77891.

[0063] In certain embodiments, a composition of the present disclosure may be for regulating a duration of cleaning of a user’s teeth. In certain embodiments, the regulation of the duration of cleaning a user’s teeth may be a duration desired by the user, desired by local dental practices, or both. In certain embodiments, the duration of cleaning a user’s teeth may be at least 2 minutes or at least 3 minutes. In certain embodiments, the duration of cleaning a user’s teeth may be at least 100 seconds, at least 101 seconds, at least 102 seconds, at least 103 seconds, at least 104 seconds, at least 105 seconds, at least 106 seconds, at least 107 seconds, at least 108 seconds, at least 109 seconds, at least 110 seconds, at least 111 seconds, at least 112 seconds, at least 113 seconds, at least 114 seconds, at least 115 seconds, at least 116 seconds, at least 117 seconds, at least 118 seconds, at least 119 seconds, at least 120 seconds, at least 121 seconds, at least 122 seconds, at least 123 seconds, at least 124 seconds, at least 125 seconds, at least 126 seconds, at least 127 seconds, at least 128 seconds, at least 129 seconds, at least 130 seconds, at least 131 seconds, at least 132 seconds, at least 133 seconds, at least 134 seconds, at least 135 seconds, at least 136 seconds, at least 137 seconds, at least 138 seconds, at least 139 seconds, at least 140 seconds, at least 141 seconds, at least 142 seconds, at least 143 seconds, at least 144 seconds, at least 145 seconds, at least 146 seconds, at least 147 seconds, at least 148 seconds, at least 149 seconds, at least 150 seconds, at least 151 seconds, at least 152 seconds, at least 153 seconds, at least 154 seconds, at least 155 seconds, at least 156 seconds, at least 157 seconds, at least 158 seconds, at least 159 seconds, at least 160 seconds, at least 161 seconds, at least 162 seconds, at least 163 seconds, at least 164 seconds, at least 165 seconds, at least 166 seconds, at least 167 seconds, at least 168 seconds, atleast 169 seconds, at least 170 seconds, at least 171 seconds, at least 172 seconds, at least 173 seconds, at least 174 seconds, at least 175 seconds, at least 176 seconds, at least 177 seconds, at least 178 seconds, at least 179 seconds, or at least 180 seconds.Methods and uses of an oral care composition as described herein

[0064] In certain embodiments, a composition as described herein is provided for regulating a duration of cleaning of a user’s teeth and / or gums.

[0065] In certain embodiments, there is provided herein uses of a composition a described herein for regulating a duration of cleaning of a user’s teeth and / or gums.

[0066] As used herein, “a duration” of cleaning a user’s teeth and / or gums may be any duration desired by the user. In certain embodiments, the duration of cleaning may encompass a time wherein the composition is applied to the mouth of the user until the user completes their desired cleaning, such as for example about 2 minutes to about 3 minutes. In certain embodiments, the duration of cleaning may comprise a duration desired by the user that is recommended by local regulatory guidelines or suggestions. In certain embodiments, the duration of cleaning may comprise at least 100 seconds, at least 101 seconds, at least 102 seconds, at least 103 seconds, at least 104 seconds, at least 105 seconds, at least 106 seconds, at least 107 seconds, at least 108 seconds, at least 109 seconds, at least 110 seconds, at least 111 seconds, at least 112 seconds, at least 113 seconds, at least 114 seconds, at least 115 seconds, at least 116 seconds, at least 117 seconds, at least 118 seconds, at least 119 seconds, at least 120 seconds, at least 121 seconds, at least 122 seconds, at least 123 seconds, at least 124 seconds, at least 125 seconds, at least 126 seconds, at least 127 seconds, at least 128 seconds, at least 129 seconds, at least 130 seconds, at least 131 seconds, at least 132 seconds, at least 133 seconds, at least 134 seconds, at least 135 seconds, at least 136 seconds, at least 137 seconds, at least 138 seconds, at least 139 seconds, at least 140 seconds, at least 141 seconds, at least 142 seconds, at least 143 seconds, at least 144 seconds, at least 145 seconds, at least 146 seconds, at least 147 seconds, at least 148 seconds, at least 149 seconds, at least 150 seconds, at least 151 seconds, at least 152 seconds, at least 153 seconds, at least 154 seconds, at least 155 seconds, at least 156 seconds, at least 157 seconds, at least 158 seconds, at least 159 seconds, at least 160 seconds, at least 161 seconds, at least 162 seconds, at least 163 seconds, at least 164 seconds, at least 165 seconds, at least 166 seconds, at least 167 seconds, at least 168 seconds, at least 169 seconds, at least 170 seconds, at least 171 seconds, at least 172 seconds, at least 173 seconds, at least 174 seconds, at least 175 seconds, at least 176 seconds, at least 177 seconds, at least 178 seconds, at least 179 seconds, or at least 180 seconds. In certain embodiments,the duration of cleaning of the user’s teeth and / or gums may be between about 2 minutes and about 3 minutes.

[0067] In certain embodiments, there is provided herein methods of cleaning a user’s teeth and / or gums, wherein the method comprises steps of: applying a composition as disclosed herein to the mouth of the user; and brushing with a brush, teeth of the user with the composition until substantially all of the isomalt encapsulated gas pellet has dissolved. In certain embodiments, the step of applying comprises an amount of the composition desired by the user, an amount determined by a local regulatory authority or an amount recommended by local dental practice.

[0068] As used herein, the term “cleaning” in reference to a user’s teeth and / or gums may comprise any form of removing or preventing one or more of stains, plaque, bad breath, bacteria, mouth disease, mouth pain; or to improve or maintain a desired oral health of the user. In certain embodiments, the cleaning is performed by applying a composition as described herein to a mouth of a user and cleaning with, for example, a toothbrush, the teeth and / or gums of the user.

[0069] In certain embodiments, the method comprises the brushing with a brush, teeth of the user with the composition until substantially all of the isomalt encapsulated gas pellet has dissolved. In certain embodiments, the user may determine that substantially all of the isomalt encapsulated gas pellets have dissolved due to the absence of a physical and / or auditory stimulus that was present prior to substantially all of the isomalt encapsulated gas pellets dissolving. In certain embodiments, the user may determine that substantially all of the isomalt encapsulated gas pellet have dissolved due to the absence of popping that was present prior to substantially all of the isomalt encapsulated gas pellets dissolving.

[0070] In certain embodiments, the method may further comprise a step of applying the composition to a brush before the step of applying the composition to the mouth of the user. In certain embodiments, the method may further comprise a step of applying the composition to the brush before the step of applying the composition to the mouth of the user, such that the composition is transferred from its original containing unit, such as a toothpaste dispenser or toothpaste tube, to the brush and then from the brush to the user’s mouth.ExamplesPreparation of an oral care composition comprising an isomalt encapsulated gas pellet in a base for regulating a duration of cleaning of a user’s teeth and / or gums

[0071] An exemplary base of a composition for testing contained: 10.00%-50.00% caprylic triglyceride, 10.00%-30.00% isomalt, 5.00%-20.00% hydrated silica, 5.00%-20.00% xylitol, 1.00%- 5.00% sodium bicarbonate, 1.00%-10.00% sorbitol, 1.00%-5.00% calcium hydroxyapatite, 1.00%-5.00% erythritol, 1.00%-5.00% sodium lauroyl sarcosinate, 1.00%-3.00% aroma / flavor, 1.00%-3.00% menthol, 1.00%-3.00% xanthan gum, 0.10%-2.00% PEG-40 hydrogenated castor oil, 0.10%-2.00% zinc citrate, 0.10%-2.00% Mentha Piperita oil, 0.10%-2.00% Mentha Viridis leaf oil, 0.10%-2.00% potassium citrate, 0.10%-2.00% Siraitia Grosvenorii fruit extract, 0.10%-2.00% sodium saccharin, 0.10%-2.00% potassium bitartrate, 0.01 %-1.00% carbon dioxide, 0.01 %-1.00% sodium benzoate, 0.01%-1.00% rebaudioside A, 0.01%-1.00% maltodextrin, 0.01 %-1.00% carvone, 0.01 %-1.00% denatured alcohol, 0.01%-1.00% limonene, 0.01 %-1.0% sodium chloride, 0.001 %-0.01% hydrolyzed Gardenia Florida extract, 0.001 %-0.01% glycyrrhizic acid, 0.0001 %-0.01% gamma-terpinene, 0.01%-1.00% water. The composition was tested with and without Titanium Dioxide (Cl 77891). The aforementioned components were used in a base of the composition and the amount of isomalt encapsulated gas pellets were varied.

[0072] A plurality of isomalt encapsulated gas pellets with an average size of 4 mm with a 5% size variance were used to prepare the composition.

[0073] Compositions prepared wherein the isomalt encapsulated gas pellets were about 10% w / w of the composition did not exhibit a substantial popping sensation or stimulus and any minimal popping sensation or stimulus ceased after about 1-minute following administration to the mouth of a user.

[0074] Compositions prepared wherein the isomalt encapsulated gas pellets were about 17% w / w of the composition exhibited a popping sensation or stimulus for about 1.5 minutes to about 2 minutes following administration to the mouth of a user.

[0075] Compositions prepared wherein the isomalt encapsulated gas pellets were about 20% w / w of the composition exhibited a popping sensation or stimulus for about 1.6 minutes to about 2.5 minutes following administration to the mouth of a user. At an isomalt encapsulated gas pellet amount of 20% w / w, the cumulative relative frequency was at or above two minutes.

[0076] In the present disclosure, all terms referred to in singular form are meant to encompass plural forms of the same. Likewise, all terms referred to in plural form are meant to encompass singular forms of the same. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure pertains.

[0077] As used herein, the term “about” refers to an approximately + / -10 % variation from a given value. It is to be understood that such a variation is always included in any given value provided herein, whether or not it is specifically referred to.

[0078] As used herein, the term “substantially” refers to an approximately +1-5 % variation from a given value. If a value is not used, then substantially means almost completely, but perhaps with some variation, contamination and / or additional component. In some embodiments, “substantially” may include completely.

[0079] It should be understood that the compositions, products, uses and methods are described in terms of "comprising," "containing," or "including" various components or steps, the compositions, products, uses and methods can also "consist essentially of’ or "consist of the various components and steps”. Moreover, the indefinite articles "a" or "an”, as used in the claims, are defined herein to mean one or more than one of the element that it introduces.

[0080] For the sake of brevity, only certain ranges are explicitly disclosed herein. However, ranges from any lower limit may be combined with any upper limit to recite a range not explicitly recited, as well as, ranges from any lower limit may be combined with any other lower limit to recite a range not explicitly recited, in the same way, ranges from any upper limit may be combined with any other upper limit to recite a range not explicitly recited. Additionally, whenever a numerical range with a lower limit and an upper limit is disclosed, any number and any included range falling within the range are specifically disclosed. In particular, every range of values (of the form, "from about a to about b," or, equivalently, "from approximately a to b," or, equivalently, "from approximately a-b" or, “from a to b”) disclosed herein is to be understood to set forth every number and range encompassed within the broader range of values even if not explicitly recited. Thus, every point or individual value may serve as its own lower or upper limit combined with any other point or individual value or any other lower or upper limit, to recite a range not explicitly recited.

[0081] Therefore, the present disclosure is well adapted to attain the ends and advantages mentioned as well as those that are inherent therein. The particular embodiments disclosed above are illustrative only, as the present disclosure may be modified and practiced in different but equivalent manners apparent to those skilled in the art having the benefit of the teachings herein. Although individual embodiments are discussed, the disclosure covers all combinations of all those embodiments. Furthermore, no limitations are intended to the details of construction or design herein shown, other than as described in the claims below. Also, the terms in the claims have their plain, ordinary meaning unless otherwise explicitly and clearly defined by the patentee. It is therefore evident that the particular illustrative embodiments disclosed above may be altered or modified and all such variations areconsidered within the scope and spirit of the present disclosure. If there is any conflict in the usages of a word or term in this specification and one or more patent(s) or other documents that may be referenced herein, the definitions that are consistent with this specification should be adopted.

[0082] Many obvious variations of the embodiments set out herein will suggest themselves to those skilled in the art in light of the present disclosure. Such obvious variations are within the full intended scope of the appended claims.

Claims

ClaimsWhat is claimed is:1 . An oral care composition comprising an isomalt encapsulated gas pellet in a base, wherein a gas encapsulated within the isomalt encapsulated gas pellet is encapsulated in the isomalt prior to administration of the composition in a mouth of a user and the isomalt encapsulated gas pellet dissolves after the composition is administered to the mouth of the user.2 The composition of claim 1 , wherein the isomalt encapsulated gas pellet comprises a plurality of isomalt encapsulated gas pellets.3 The composition of claim 1 or 2, wherein a portion of the gas encapsulated by the isomalt is contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 1 minute, or at least 2 minutes following administration to the mouth of the user.4 The composition of any one of claims 1-3, wherein a portion of the gas encapsulated by the isomalt encapsulated gas pellet is contained in the isomalt encapsulated gas pellet for about 2 minutes to about 3 minutes following administration to the mouth of the user.5 The composition of any one of claims 1-4, wherein substantially all of the gas encapsulated by the isomalt encapsulated gas pellet is contained in the isomalt encapsulated gas pellet for at least 30 seconds, at least 1 minute or at least 2 minutes following administration to the mouth of the user.6 The composition of any one of claims 1-5, wherein substantially all of the gas encapsulated by the isomalt encapsulated gas pellet is contained in the isomalt encapsulated gas pellet for about 2 minutes to about 3 minutes following administration to the mouth of the user.7 The composition of any one of claims 1-6, wherein the isomalt encapsulated pellet dissolves within at least 1 minute, at least 2 minutes or at least 3 minutes after administration to the mouth of the user.8 The composition of any one of claims 1-7, wherein the isomalt encapsulated pellet dissolves in about 2 minutes to about 3 minutes after administration to the mouth of the user.9 The composition of any one of claims 1-8, wherein the gas encapsulated by the isomalt is carbon dioxide.10 The composition of any one of claims 1-9, wherein the isomalt encapsulated gas pellet has an average size of between 2 mm and 5 mm.

11. The composition of any one of claims 1-10, wherein the isomalt encapsulated gas pellet has an average size of about 4 mm.

12. The composition of any one of claims 1-11 , wherein the isomalt encapsulated gas pellet comprises 15 % to 25 % w / w of the composition.

13. The composition of any one of claims 1-12, wherein the isomalt encapsulated gas pellet comprises about 20 % w / w of the composition.

14. The composition of any one of claims 1-13, wherein the base comprises one or more surfactant, one or more silica, one or more flavouring agent, one or more oil, one or more additional agents or any combination thereof.

15. The composition of any one of claims 1-14, wherein the base is substantially free of water.

16. The composition of any one of claims 1-15, wherein the base comprises less than about 2%, less than about 1.95%, less than about 1.9%, less than about 1.85%, less than about 1.8%, less than about 1 75%, less than about 1.7%, less than about 1 .65%, less than about 1 .6%, less than about 1 .55%, less than about 1.5%, less than about 1.45%, less than about 1.4%, less than about 1.35%, less than about 1 3 , less than about 1.25%, less than about 1.2%, less than about 1.15%, less than about 1.1%, less than about 1.05%, less than about 1%, less than about 0.95%, less than about 0.9%, less than about 0 85 , less than about 0.8%, less than about 0.75%, less than about 0.7%, less than about 0.65%, less than about 0.6%, less than about 0.55%, less than about 0.5%, less than about 0.45%, less than about less than about 0.35%, less than about 0.3%, less than about 0.25%, less than about 0.2%, less than about 0.15%, less than about 0.1% or less than about 0.05% water.17 The composition of any one of claims 1-16, wherein the one or more silica comprises hydrated silica, silicon dioxide, or any combination thereof.18 The composition of any one of claims 1-17, wherein the one or more flavouring agent comprises xylitol menthol, sorbitol, erythritol, Mentha Piperita oil, Mentha Viridis leaf oil, Siraitia Grosvenorii fruit extract rebaudioside A, maltodextrin, carvone, limonene, hydrolyzed Gardenia Florida extract, sodium saccharin, glycyrrhizic acid, gamma-terpinene or any combination thereof.19 The composition of any one of claims 1-18, wherein the one or more fat or oil comprises caprylic triglyceride, PEG-40 hydrogenated castor oil or any combination thereof.

20. The composition of any one of claims 1-19, wherein the one or more surfactant comprises sodium lauroyl sarcosinate, sodium lauryl sulfate, sodium alkylsulfo succinate, sodium cocomonoglyceride sulfonate, sucrose fatty acid esters or any combination thereof.

21. The composition of any one of claims 1-20, wherein the one or more additional agent comprises hydrophobic plasticizer, calcium hydroxyapatite, sodium bicarbonate, xanthan gum, zinc citrate, potassium citrate, stannous fluoride, potassium bitartrate, sodium benzoate, denatured alcohol, sodium chloride, water or any combination thereof.

22. The composition of claim 21 , wherein the zinc citrate is zinc citrate dihydrate.

23. The composition of any one of claims 1-22, wherein the composition further comprises a pigment or coloring agent.

24. The composition of claim 23, wherein the pigment or coloring agent is titanium dioxide.

25. A composition comprising: caprylic triglyceride, isomalt, hydrated silica, xylitol, sodium bicarbonate, sorbitol, erythritol, sodium lauroyl sarcosinate, aroma, flavor, menthol, xanthan gum, PEG-40 hydrogenated castor oil, zinc citrate, Mentha Piperita oil, Mentha Viridis leaf oil, potassium citrate, stannous fluoride, Siraitia Grosvenorii fruit extract, sodium saccharin, potassium bitartrate, carbon dioxide, sodium benzoate, rebaudioside A, maltodextrin, carvone, denatured alcohol, limonene, sodium chloride, hydrolyzed Gardenia Florida extract, glycyrrhizic acid, gamma-terpinene, and water.

26. A composition comprising: caprylic triglyceride, isomalt, hydrated silica, xylitol, sodium bicarbonate, sorbitol, erythritol, sodium lauroyl sarcosinate, aroma, flavor, menthol, xanthan gum, PEG-40 hydrogenated castor oil, zinc citrate, Mentha Piperita oil, Mentha Viridis leaf oil, potassium citrate, stannous fluoride, Siraitia Grosvenorii fruit extract, sodium saccharin, potassium bitartrate, carbon dioxide, sodium benzoate, rebaudioside A, maltodextrin, carvone, denatured alcohol, limonene, sodium chloride, hydrolyzed Gardenia Florida extract, glycyrrhizic acid, gamma-terpinene, titanium dioxide and water.

27. The composition of claim 25 or 26, further comprising stannous fluoride.

28. A composition comprising (w / w): 10.00%-50.00% caprylic triglyceride, 10.00%-30.00% isomalt, 5 00%-20.00% hydrated silica, 5.00%-20.00% xylitol, 1.00%-5.00% sodium bicarbonate, 1.00%-10.00% sorbitol, 1.00%-5.00% calcium hydroxyapatite, 1.00%-5.00% erythritol, 1.00%-5.00% sodium lauroyl sarcosinate, 1.00%-3.00% aroma / flavor, 1.00%-3.00% menthol, 1.00%-3.00% xanthan gum, 0.10%- 2 00% PEG-40 hydrogenated castor oil, 0.10%-2.00% zinc citrate, 0.10%-2.00% Mentha Piperita oil,0.10%-2.00% Mentha Viridis leaf oil, 0.10%-2.00% potassium citrate, 0.10%-2.00% Siraitia Grosvenorii fruit extract, 0.10%-2.00% sodium saccharin, 0.10%-2.00% potassium bitartrate, 0.01 %-1.00% carbon dioxide, 0.01%-1.00% sodium benzoate, 0.01 %-1.00% rebaudioside A, 0.01 %-1.00% maltodextrin, 0.01%-1.00% carvone, 0.01 %-1.00% denatured alcohol, 0.01%-1.00% limonene, 0.01 %-1.0% sodium chloride, 0.001 %-0.01% hydrolyzed Gardenia Florida extract, 0.001 %-0.01 % glycyrrhizic acid, 0 0001 %-0.01% gamma-terpinene, and 0.01 %-1.00% water.29 A composition comprising (w / w): 10.00%-50.00% caprylic triglyceride, 10.00%-30.00% isomalt, 5 00 -20.00% hydrated silica, 5.00%-20.00% xylitol, 1.00%-5.00% sodium bicarbonate, 1.00%-10.00% sorbitol, 1.00%-5.00% calcium hydroxyapatite, 1.00%-5.00% erythritol, 1.00%-5.00% sodium lauroyl sarcosinate, 1.00%-3.00% aroma / flavor, 1.00%-3.00% menthol, 1.00%-3.00% xanthan gum, 0.10%- 2 00 PEG-40 hydrogenated castor oil, 0.10%-2.00% zinc citrate, 0.10%-2.00% Mentha Piperita oil, 0 10 -2.00% Mentha Viridis leaf oil, 0.10%-2.00% potassium citrate, 0.10%-2.00% Siraitia Grosvenorii fruit extract, 0.10%-2.00% sodium saccharin, 0.10%-2.00% potassium bitartrate, 0.01 %-1.00% carbon dioxide, 0.01%-1.00% sodium benzoate, 0.01 %-1.00% rebaudioside A, 0.01 %-1.00% maltodextrin, 0 01 -1.00% carvone, 0.01 %-1.00% denatured alcohol, 0.01%-1.00% limonene, 0.01 %-1.0% sodium chloride, 0.001 %-0.01% hydrolyzed Gardenia Florida extract, 0.001 %-0.01 % glycyrrhizic acid, 0 0001 %-0.01% gamma-terpinene, 0.01 %-1.00% water and titanium dioxide.30 The composition of claim 28 or 29, further comprising (w / w): 0.10%-2.00% stannous fluoride.31 The composition of any one of claims 1-30, wherein the base is a toothpaste, gel, lozenge, chewing gum or tablet.32 The composition of any one of claims 1-31 for regulating a duration of cleaning of a user’s teeth and / or gums.33 Use of the composition of any one of claims 1-31 for regulating a duration of cleaning of a user’s teeth and / or gums.34 A method of cleaning a user's teeth and / or gums, the method comprising the steps of: applying the composition of any one of claims 1-31 to the mouth of the user; and brushing with a brush, teeth and / or gums of the user with the composition until substantially all of the isomalt encapsulated gas pellet has dissolved.35 The method of claim 34, further comprising, a step of applying the composition to the brush before the step of applying the composition to the mouth of the user.

36. The method of claim 34 or 35, wherein substantially all of the isomalt encapsulated gas pellet has dissolved when the composition ceases popping in the mouth of the user.