Advanced home toilet system for monitoring urine components in real time while urination

Abstract

A urine analysis system that includes an integration sphere and multiple radiation sources of different frequencies, and a detection unit that includes a detection unit lens, an apertured ellipsoid reflector and a sensor, wherein the detection unit is configured to: receive a received radiation beam, prevent the received radiation beam from reaching a sensor of the detection unit when the received radiation beam is a non- interaction output radiation beam that did not interact with the urine sample; direct the received radiation beam to the sensor of the detection unit when the received radiation beam is an interaction output radiation beam that interacted with the urine sample and changed a direction of propagation due to the interaction, and generate detection signals indicative of the interaction output radiation beam.

Description

10064-USADVANCED HOME TOILET SYSTEM FOR MONITORING URINE COMPONENTS IN REAL TIME WHILE URINATIONCROSS REFERENCE

[0001] This application claims priority from US provisional patent serial number 63 / 714,090 filing date October 30, 2024, which is incorporated herein in its entirety. BACKGROUND

[0002] Urine analysis is a critical component in medical diagnostics, providing valuable insights into a person's health by detecting and monitoring various conditions such as infections, kidney disease, and diabetes. Traditional urine analysis methods often involve manual sample collection and laboratory testing, which can be timeconsuming and prone to human error. As healthcare systems strive for more efficient and accurate diagnostic tools, there is a growing need for automated and non-invasive solutions that can provide real-time analysis and feedback.

[0003] The integration of advanced optical technologies in medical diagnostics has opened new avenues for innovation in urine analysis systems. Optical sensors and radiation sources can be used to detect specific biomarkers in urine samples, offering a more precise and rapid assessment compared to conventional methods. However, challenges remain in ensuring the accuracy and reliability of these systems, particularly in terms of managing ambient light interference and maintaining consistent radiation output. As the demand for home-based and point-of-care diagnostic tools increases, developing a robust and user-friendly urine analysis system that addresses these challenges is of paramount importance.SUMMARY

[0004] According to an embodiment, there is provided a urine analysis system that includes an illumination unit and a detection unit. The illumination unit includes an integration sphere and multiple radiation sources of different frequencies.

[0005] The integration sphere is configured to integrate radiation from concurrently activated radiation sources of the multiple radiation sources to output, through an output aperture of the integration sphere, a output radiation beam (ORB) that maintains a constant relationship between the radiation from the concurrently activated radiation sources.

[0006] The illumination unit further comprises a limiter that surrounds the output aperture and is configured to allow an output of the ORB through the output aperture10064-US that approaches the output aperture at a first angular range, and to reflect, within the integration sphere, radiation that approaches the output aperture at an angle outside the first angular range. An optical axis of each radiation source of the multiple radiation sources does not virtually pass through the output aperture.

[0007] The detection unit includes a detection unit lens, an apertured ellipsoid reflector and a sensor, wherein the detection unit is configured to: (a) receive a received radiation beam; (b) prevent the received radiation beam from reaching a sensor of the detection unit when the received radiation beam is an non-interaction ORB that did not interact with the urine sample, (c) direct the received radiation beam to the sensor of the detection unit when the received radiation beam is an interaction ORB that interacted with the urine sample and changed a direction of propagation due to the interaction, and (d) generate detection signals indicative of the interaction ORB.

[0008] According to an embodiment, the detection unit is also configured to prevent the received radiation beam from reaching the sensor when the received radiation beam is an ORB that interacted with the urine sample but did not change a direction of propagation due to the interaction.

[0009] According to an embodiment, a center of the detection unit lens is located at first focal point of the ellipsoid reflector, and the sensor is located at a second focal point of the ellipsoid reflector.

[0010] According to an embodiment, the apertured ellipsoid reflector includes a bypass aperture that is configured to receive the non-interaction ORB or a received radiation beam that is an ORB that interacted with the urine sample but did not change a direction of propagation due to the interaction.

[0011] According to an embodiment, the radiation sources are arranged in a circular arrangement.

[0012] According to an embodiment, the radiation sources are arranged in any manner that differs from a circular arrangement - in a random pattern, in a pseudorandom pattern, in a polygon pattern, in an ordered manner that differs from a circular arrangement, and the like.

[0013] According to an embodiment, the radiation sources are positioned at a first half of the integration sphere.

[0014] According to an embodiment, the radiation sources are positioned at a second half of the integration sphere.10064-US

[0015] According to an embodiment, the radiation sources are positioned at both halves of the integration sphere.

[0016] According to an embodiment, the radiation sources are arranged in a circular arrangement and the optical axes of the radiation sources are oriented to a virtual axis of the integration sphere that passes through a center of the output aperture by an azimuth angle that ranges between one to thirty degrees.

[0017] According to an embodiment, the detection unit further includes one or more ambient light blocking elements for blocking ambient light from reaching the sensor.

[0018] According to an embodiment, an optical axis of the output radiation beam when existing the output aperture is aligned with an optical axis of the detection unit lens.

[0019] According to an embodiment, the urine analysis system includes a controller for independently determining a timing of activation of each one of the multiple radiation sources.

[0020] According to an embodiment, the urine analysis system includes coupling elements for coupling the detection unit and the detection unit to a toilet seat.

[0021] According to an embodiment, the multiple radiation sources are located within elongated recesses, wherein the elongated recesses are configured to spatially filter radiation beams emitted from the radiation sources.

[0022] According to an embodiment there is provided a method for urine analysis, the method includes (a) activating radiation sources of multiple radiation sources of an illumination unit of a urine analysis system; (b) integrating, by an integration sphere of the illumination unit, the radiation from the activated radiation sources to output, through an output aperture of the integration sphere, a output radiation beam (ORB) that maintains a constant relationship between the radiation from the concurrently activated radiation sources; wherein an optical axis of each radiation source of the multiple radiation sources does not virtually pass through the output aperture; (c) allowing, by a limiter of the illumination unit that surrounds the output aperture, an output of the ORB through the output aperture that approaches the output aperture at a first angular range; (d) reflecting, by the limiter, within the integration sphere, radiation that approaches the output aperture at an angle outside the first angular range; (e) receiving by a detection unit lens of a detection unit of the urine analysis system, a received radiation beam; (f) preventing the received radiation beam from reaching a sensor of the detection unit when the received radiation beam is an non-10064-US interaction ORB that did not interact with the urine sample, (g) directing the received radiation beam to the sensor when the received radiation beam is an interaction ORB that interacted with the urine sample and changed a direction of propagation due to the interaction, and (h) generating detection signals indicative of the interaction ORB.

[0023] According to an embodiment a center of the detection unit lens is located at a first focal point of the ellipsoid reflector, and the sensor is located at a second focal point of the ellipsoid reflector.

[0024] According to an embodiment, the method includes receiving, by a bypass aperture of the apertured ellipsoid reflector, the ORB when the interaction unchanged the direction of propagation of the ORB, without reflecting the ORB towards the sensor.

[0025] According to an embodiment, the radiation sources are arranged in a circular arrangement.

[0026] According to an embodiment, the radiation sources are positioned at a first half of the integration sphere.

[0027] According to an embodiment, the radiation sources are arranged in a circular arrangement and the optical axes of the radiation sources are oriented to a virtual axis of the integration sphere that passes through a center of the output aperture by an azimuth angle that ranges between one to thirty degrees.

[0028] According to an embodiment, the method includes blocking ambient light from reaching the sensor by ambient light blocking elements.

[0029] According to an embodiment, an optical axis of the output radiation beam when existing the output aperture is aligned with an optical axis of the detection unit lens.

[0030] According to an embodiment, the method includes independently determining, by a controller, a timing of activation of each one of the multiple radiation sources.

[0031] According to an embodiment, the method includes coupling, by coupling elements , the detection unit, and the detection unit to a toilet seat.BRIEF DESCRIPTION OF THE DRAWINGS

[0032] The subject matter that is regarded as the invention is particularly pointed out and distinctly claimed in the concluding portion of the specification. The invention , however, both as to organization and method of operation , together with objects , features , and advantages thereof, may best be understood by reference to the following detailed description when read with the accompanying drawing in which:10064-US

[0033] FIG. 1 illustrates an example of a toilet seat, a detection unit, an illumination unit, and a non-interaction output radiation beam;

[0034] FIG. 2 illustrates an example of a toilet seat, a detection unit, an illumination unit, and an interaction output radiation beam;

[0035] FIG. 3 illustrates an example of an illumination unit;

[0036] FIG. 4 illustrates an example of a detection unit;

[0037] FIG. 5 illustrates an example of a method.DETAILED DESCRIPTION OF THE DRAWINGS

[0038] According to an embodiment, there is provided a system and methos for analyzing urine given when a patient uses a toilet seat.

[0039] It has been surprisingly found that deflected radiation (illuminated radiation that was deflected due to an interaction with a urine sample) provides more beneficial information than direct radiation (illuminated radiation that did not change its direction of propagation was due to an interaction with a urine sample).

[0040] It has been surprisingly found that the analysis of the urine is significantly improved when the urine sample when illuminated with radiation generated from multiple radiation sources of multiple frequencies - regardless of the orientations of the optical axes of the radiation sources.

[0041] According to an embodiment, there is provided a method and system that enables the different radiation sources to operate as a single radiation source.

[0042] According to an embodiment there is provided an illumination unit that includes an integration sphere that is configured to integrate lights from activated radiation sources to provide, following integration by diffusion, an output radiation beam that maintains the relative intensity ratio between radiation provided by different activated radiation sources.

[0043] According to the embodiment the output radiation beam interacts with the urine sample and changes its direction of propagation due to the interaction to provide a received radiation beam that once received by the sensor, is at two standard deviations above a noise sensed by the sensor.

[0044] According to an embodiment, the urine analysis system includes a triggering sensor for triggering the operation of the illumination unit and the detection unit, when sensing a triggering condition. Examples of a triggering sensor are illustrated in US patent 11698370 which is incorporated herein by reference.10064-US

[0045] Figure 1 illustrates an example of a toilet seat 12, a detection unit 200, an illumination unit 100 and a non-interaction output radiation beam 21. The noninteraction output radiation beam 21 does not interact with any urine sample and propagates till reaching the detection unit 200. It should not reach a sensor of the detection unit 200.

[0046] Figure 2 illustrates an example a toilet seat 12, a detection unit 200, an illumination unit 100 and an interaction output radiation beam 22. The interaction output radiation beam is an output radiation beam that interacted with urine sample 14 and changed it direction of propagation to provide a received radiation beam that reaches the detection unit.

[0047] While figure 2 illustrates a change of direction of propagation along one direction (for example to the left) - but the change of direction can be of any angle.

[0048] Figure 1 and 3 also illustrates a controller 82 for controlling the operation of the detection unit 200 and / or the illumination unit 100, and a processing circuit 82 for processing detection signals generated by the detection unit. The processing may include spectral analysis.

[0049] Figure 3 illustrates an example of an illumination unit 100.

[0050] Figure 4 illustrates an example of a detection unit 200.

[0051] According to an embodiment, there is provided a urine analysis system that includes an illumination unit (denoted 100 in figures 1-3) and a detection unit (denoted 200 in figures 1,2 and 4).

[0052] The illumination unit (see figure 3) includes an integration sphere 120 and multiple radiation sources (such as radiation sources 101, 103, and 105) of different frequencies.

[0053] According to an embodiment, the multiple radiation sources are located within elongated recesses (111, 112, 113, 114, 115) associated with integration sphere 120.

[0054] According to an embodiment the multiple radiation sources are followed by spatial filters for preventing a radiation beam from any of the multiple radiation sources to directly propagate through the output aperture.

[0055] According to an embodiment, the integration sphere is configured to integrate radiation from concurrently activated radiation sources of the multiple radiation sources to output, through an output aperture 140 of the integration sphere, a output radiation beam (ORB).10064-US

[0056] According to an embodiment, the ORB maintains a constant relationship between the radiation from the concurrently activated radiation sources. The constant relationship is a relationship between the power or the intensity of radiation from different concurrently activated radiation sources. The constant relationship assist in providing a more accurate spectral analysis of signals - and allows to determine the impact, per frequency of the urine sample on the ORB.

[0057] According to an embodiment, the integration sphere is configured to output the ORB at the same angle regarding the location of one or more activated radiation sources.

[0058] According to an embodiment, the ORB exhibits a uniform intensity at different locations (for example all locations) across the output aperture.

[0059] The illumination unit 100 further comprises a limiter 130 that surrounds the output aperture 140 and is configured to allow an output of the ORB through the output aperture that approaches the output aperture at a first angular range 142, and to reflect (using reflecting portion 144), within the integration sphere, radiation that approaches the output aperture at an angle outside the first angular range.

[0060] According to an embodiment, the elongated recesses 111-115 are configured to spatially filter radiation beams emitted from the radiation sources to prevent a direct propagation of radiation from the radiation sources through the output aperture.

[0061] According to an embodiment the elongated recesses do not perform spatial filtering.

[0062] An optical axis (121-125) of each radiation source of the multiple radiation sources does not virtually pass through the output aperture.

[0063] The detection unit 200 includes a detection unit lens 230 such as a focusing lens, an apertured ellipsoid reflector 220 and a sensor 210, wherein the detection unit is configured to: a. Receive a received radiation beam. b. Prevent the received radiation beam from reaching a sensor of the detection unit when the received radiation beam is an non-interaction ORB (denoted 21) that did not interact with the urine sample. c. Direct the received radiation beam to the sensor of the detection unit when the received radiation beam is an interaction ORB (denoted 23) that interacted with the urine sample and changed a direction of propagation due to the interaction.10064-US d. Generate detection signals indicative of the interaction ORB.

[0064] According to an embodiment, the detection unit is also configured to prevent the received radiation beam from reaching the sensor when the received radiation beam is an ORB that interacted with the urine sample but did not change a direction of propagation due to the interaction.

[0065] According to an embodiment, a center of the detection unit lens is located at a first focal point of the ellipsoid reflector, and the sensor is located at a second focal point of the ellipsoid reflector.

[0066] According to an embodiment, the apertured ellipsoid reflector includes a bypass aperture that is configured to receive the non-interaction ORB.

[0067] According to an embodiment, the radiation sources are arranged in a circular arrangement.

[0068] According to an embodiment, the radiation sources are arranged in any manner that differs from a circular arrangement - in a random pattern, in a pseudorandom pattern, in a polygon pattern, in an ordered manner that differs from a circular arrangement, and the like.

[0069] According to an embodiment, the radiation sources are positioned at a first half of the integration sphere.

[0070] According to an embodiment, the radiation sources are positioned at a second half of the integration sphere.

[0071] According to an embodiment, the radiation sources are positioned at both halves of the integration sphere.

[0072] According to an embodiment, the radiation sources are arranged in a circular arrangement and the optical axes of the radiation sources are oriented to a virtual axis of the integration sphere that passes through a center of the output aperture by an azimuth angle that ranges between one to thirty degrees.

[0073] According to an embodiment, the detection unit further includes ambient light blocking elements for blocking ambient light from reaching the sensor.

[0074] According to an embodiment one or more light blocking elements are located on a portion of the ellipsoid reflector that is expected to receive ambient light - for example a lower portion of the ellipsoid reflector.

[0075] According to an embodiment, an optical axis of the output radiation beam when existing the output aperture is aligned with an optical axis of the detection unit lens.10064-US

[0076] According to an embodiment, the urine analysis system includes a controller for independently determining a timing of activation of each one of the multiple radiation sources.

[0077] According to an embodiment, the urine analysis system includes coupling elements for coupling the detection unit and the detection unit to a toilet seat. The coupling elements are selected of mechanical coupling element, magnetic coupling elements, gluing elements, and the like.

[0078] Figure 5 illustrates an example of method 300 for urine analysis.

[0079] According to an embodiment, method 300 includes: a. Step 310 of activating radiation sources of multiple radiation sources of an illumination unit of a urine analysis system, the radiation sources are located within elongated recesses. b. Step 320 of integrating, by an integration sphere of the illumination unit, the radiation outputted by concurrently activated radiation sources to output, through an output aperture of the integration sphere, an output radiation beam (ORB) that maintains a constant relationship between the radiation from the concurrently activated radiation sources; wherein an optical axis of each radiation source of the multiple radiation sources does not virtually pass through the output aperture. According to an embodiment step 330 includes allowing, by a limiter of the illumination unit that surrounds the output aperture, an output of the ORB through the output aperture that approaches the output aperture at a first angular range, and reflecting, by the limiter, within the integration sphere, radiation that approaches the output aperture at an angle outside the first angular range. c. Step 340 of receiving by a detection unit lens of a detection unit of the urine analysis system, a received radiation beam. d. Step 350 of (i) preventing the received radiation beam from reaching a sensor of the detection unit when the received radiation beam is an non-interaction ORB that did not interact with the urine sample, and (ii) directing the received radiation beam to the sensor when the received radiation beam is an interaction ORB that interacted with the urine sample and changed a direction of propagation due to the interaction.10064-US e. Step 370 of generating detection signals indicative of the interaction ORB. f. Step 380 of analyzing the detection signals to provide an indication regarding the urine sample.

[0080] According to an embodiment, step 350 includes preventing the received radiation beam from reaching the sensor when the received radiation beam is an ORB that interacted with the urine sample but did not change a direction of propagation due to the interaction with the urine sample.

[0081] According to an embodiment a center of the detection unit lens is located at a first focal point of the ellipsoid reflector, and the sensor is located at a second focal point of the ellipsoid reflector.

[0082] According to an embodiment, method 300 includes receiving, by a bypass aperture of the apertured ellipsoid reflector, the ORB when the interaction unchanged the direction of propagation of the ORB, without reflecting the ORB towards the sensor - or when the ORB did not interact with the urine center.

[0083] According to an embodiment, the radiation sources are arranged in a circular arrangement.

[0084] According to an embodiment, the radiation sources are positioned at a first half of the integration sphere.

[0085] According to an embodiment, the radiation sources are arranged in a circular arrangement and the optical axes of the radiation sources are oriented to a virtual axis of the integration sphere that passes through a center of the output aperture by an azimuth angle that ranges between one to thirty degrees.

[0086] According to an embodiment, the method includes blocking ambient light from reaching the sensor by ambient light blocking elements.

[0087] According to an embodiment, an optical axis of the output radiation beam when existing the output aperture is aligned with an optical axis of the detection unit lens.

[0088] According to an embodiment, the method includes independently determining, by a controller, a timing of activation of each one of the multiple radiation sources.

[0089] According to an embodiment, the method includes coupling, by coupling elements , the detection unit, and the detection unit to a toilet seat.

[0090] In the foregoing detailed description , numerous specific details are set forth in order to provide a thorough understanding of the invention. However , it will be10064-US understood by those skilled in the art that the present invention may be practiced without these specific details. In other instances , well-known methods , procedures , and components have not been described in detail so as not to obscure the present invention.

[0091] The subject matter regarded as the invention is particularly pointed out and distinctly claimed in the concluding portion of the specification. The invention , however , both as to organization and method of operation , together with objects , features , and advantages thereof , may best be understood by reference to the following detailed description when read with the accompanying drawings.

[0092] It will be appreciated that for simplicity and clarity of illustration , elements shown in the figures have not necessarily been drawn to scale. For example , the dimensions of some of the elements may be exaggerated relative to other elements for clarity. Further , where considered appropriate , reference numerals may be repeated among the figures to indicate corresponding or analogous elements.

[0093] Because the illustrated embodiments of the present invention may for the most part , be implemented using microelectronics and / or optical components and circuits known to those skilled in the art , details will not be explained in any greater extent than that considered necessary as illustrated above , for the understanding and appreciation of the underlying concepts of the present invention and in order not to obfuscate or distract from the teachings of the present invention.

[0094] Any reference in the specification to a method should be applied mutatis mutandis to a system capable of executing the method.

[0095] Any reference in the specification to a system should be applied mutatis mutandis to a method that may be executed by the system.

[0096] In the foregoing specification , the invention has been described with reference to specific examples of embodiments of the invention. It will , however , be evident that various modifications and changes may be made therein without departing from the broader spirit and scope of the invention as set forth in the appended claims.

[0097] Moreover , the terms “front “back “top “bottom “over “under” and the like in the description and in the claims , if any , are used for descriptive purposes and not necessarily for describing permanent relative positions. It is understood that the terms so used are interchangeable under appropriate circumstances such that the embodiments of the invention described herein are , for example , capable of operation in other orientations than those illustrated or otherwise described herein.10064-US

[0098] Any arrangement of components to achieve the same functionality is effectively "associated" such that the desired functionality is achieved. Hence , any two components herein combined to achieve a particular functionality may be seen as "associated with" each other such that the desired functionality is achieved , irrespective of architectures or intermedial components. Likewise , any two components so associated can also be viewed as being "operably connected or "operably coupled to each other to achieve the desired functionality.

[0099] However , other modifications , variations and alternatives are also possible. The specifications and drawings are , accordingly , to be regarded in an illustrative rather than in a restrictive sense.

[0100] In the claims , any reference signs placed between parentheses shall not be construed as limiting the claim. The word ‘comprising’ does not exclude the presence of other elements or steps then those listed in a claim. Furthermore , the terms “a” or “an as used herein , are defined as one or more than one. Also , the use of introductory phrases such as “at least one” and “one or more” in the claims should not be construed to imply that the introduction of another claim element by the indefinite articles "a" or "an" limits any particular claim containing such introduced claim element to inventions containing only one such element , even when the same claim includes the introductory phrases "one or more" or "at least one" and indefinite articles such as "a" or "an." The same holds true for the use of definite articles. Unless stated otherwise , terms such as “first" and “second” are used to arbitrarily distinguish between the elements such terms describe. Thus , these terms are not necessarily intended to indicate temporal or other prioritization of such elements. The mere fact that certain measures are recited in mutually different claims does not indicate that a combination of these measures cannot be used to advantage.

[0101] While certain features of the invention have been illustrated and described herein , many modifications , substitutions , changes , and equivalents will now occur to those of ordinary skill in the art. It is , therefore , to be understood that the appended claims are intended to cover all such modifications and changes as fall within the true spirit of the invention.

Claims

10064-USWE CLAIM1. A urine analysis system comprising: an illumination unit comprising an integration sphere and multiple radiation sources of different frequencies, wherein the integration sphere is configured to integrate radiation from concurrently activated radiation sources of the multiple radiation sources to output, through an output aperture of the integration sphere, a output radiation beam (ORB) that maintains a constant relationship between the radiation from the concurrently activated radiation sources, wherein the illumination unit further comprises a limiter that surrounds the output aperture and is configured to allow an output of the ORB through the output aperture that approaches the output aperture at a first angular range, and to reflect, within the integration sphere, radiation that approaches the output aperture at an angle outside the first angular range; wherein an optical axis of each radiation source of the multiple radiation sources does not virtually pass through the output aperture; and a detection unit that comprises a detection unit lens, an apertured ellipsoid reflector and a sensor, wherein the detection unit is configured to: a. receive a received radiation beam; b. prevent the received radiation beam from reaching a sensor of the detection unit when the received radiation beam is a non-interaction ORB that did not interact with the urine sample; c. direct the received radiation beam to the sensor of the detection unit when the received radiation beam is an interaction ORB that interacted with the urine sample and changed a direction of propagation due to the interaction, and d. generate detection signals indicative of the interaction ORB.

2. The urine analysis system of claim 1, wherein a center of the detection unit lens is located at first focal point of the ellipsoid reflector, and the sensor is located at a second focal point of the ellipsoid reflector.

3. The urine analysis system of claim 1, wherein the apertured ellipsoid reflector comprises a bypass aperture that is configured to receive the ORB when the interaction unchanged the direction of propagation of the ORB without reflecting the ORB towards the sensor.

4. The urine analysis system of claim 1, wherein the radiation sources are arranged in a circular arrangement.

5. The urine analysis system of claim 1, wherein the radiation sources are positioned at a first half of the integration sphere.10064-US6. The urine analysis system of claim 1, wherein the radiation sources are arranged in a circular arrangement and the optical axes of the radiation sources are oriented to a virtual axis of the integration sphere that passes through a center of the output aperture by an azimuth angle that ranges between one to thirty degrees.

7. The urine analysis system of claim 1, wherein the detection unit further comprises ambient light blocking elements for blocking ambient light from reaching the sensor.

8. The urine analysis system of claim 1, wherein an optical axis of the output radiation beam when existing the output aperture is aligned with an optical axis of the detection unit lens.

9. The urine analysis system of claim 1, further comprising a controller for independently determining a timing of activation of each one of the multiple radiation sources.

10. The urine analysis system of claim 1, further comprising coupling elements for coupling the detection unit and the detection unit to a toilet seat.

11. The urine analysis system according to claim 1, wherein the multiple radiation sources are located within elongated recesses, wherein the elongated recesses are configured to spatially filter radiation beams emitted from the radiation sources.

12. A method for urine analysis, the method comprises: activating radiation sources of multiple radiation sources of an illumination unit of a urine analysis system, the radiation sources are located within elongated recesses; spatially filtering, by elongated recessed, radiation emitted from the radiation sources to provide spatially filtered radiation; integrating, by an integration sphere of the illumination unit, the spatially filtered radiation to output, through an output aperture of the integration sphere, an output radiation beam (ORB) that maintains a constant relationship between the radiation from the concurrently activated radiation sources; wherein an optical axis of each radiation source of the multiple radiation sources does not virtually pass through the output aperture; allowing, by a limiter of the illumination unit that surrounds the output aperture, an output of the ORB through the output aperture that approaches the output aperture at a first angular range; reflecting, by the limiter, within the integration sphere, radiation that approaches the output aperture at an angle outside the first angular range;10064-US receiving by a detection unit lens of a detection unit of the urine analysis system, a received radiation beam; preventing the received radiation beam from reaching a sensor of the detection unit when the received radiation beam is a non-interaction ORB that did not interact with the urine sample; directing the received radiation beam to the sensor when the received radiation beam is an interaction ORB that interacted with the urine sample and changed a direction of propagation due to the interaction; and generating detection signals indicative of the interaction ORB.

13. The method of claim 12, wherein a center of the detection unit lens is located at first focal point of the ellipsoid reflector, and the sensor is located at a second focal point of the ellipsoid reflector.

14. The method of claim 12, comprising receiving, by a bypass aperture of the apertured ellipsoid reflector, the non-interaction ORB without reflecting the non-interaction ORB towards the sensor.

15. The method of claim 12, wherein the radiation sources are arranged in a circular arrangement.

16. The method of claim 12, wherein the radiation sources are positioned at a first half of the integration sphere.

17. The method of claim 12, wherein the radiation sources are arranged in a circular arrangement and the optical axes of the radiation sources are oriented to a virtual axis of the integration sphere that passes through a center of the output aperture by an azimuth angle that ranges between one to thirty degrees.

18. The method of claim 12, further comprising blocking ambient light from reaching the sensor by ambient light blocking elements.

19. The method of claim 12, wherein an optical axis of the output radiation beam when existing the output aperture is aligned with an optical axis of the detection unit lens.

20. The method of claim 12, further comprising independently determining, by a controller, a timing of activation of each one of the multiple radiation sources.

21. The method of claim 12, further comprising coupling, by coupling elements , the detection unit, and the detection unit to a toilet seat.

22. The method according to claim 12, wherein the multiple radiation sources are located within elongated recesses, wherein the method comprises spatially filtering, by the elongated recesses, radiation beams emitted from the radiation sources.

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