Systems and methods for sensing information during pulsed field ablation

The pulsed field ablation system uses passive sensors on a catheter to sample electrophysiological activity and temperature during energy delivery intervals, addressing interference issues and improving sensing quality and efficiency in intravascular procedures.

WO2026123103A1PCT designated stage Publication Date: 2026-06-18KARDIUM
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
KARDIUM
Filing Date
2025-12-08
Publication Date
2026-06-18

AI Technical Summary

⚠Technical Problem

In intravascular or percutaneous medical procedures, such as pulsed field ablation for treating atrial fibrillation, the transmission of tissue-ablative energy interferes with the ability of electrodes to sense electrograms, degrading information quality during lesion formation.

⚗Method used

A pulsed field ablation system with a passive sensor set on a catheter device that samples electrophysiological activity and temperature during intervals between or after delivery of pulsed field ablation energy, using separate transducers or electrodes for energy delivery and sensing, to reduce interference effects.

🎯Benefits of technology

Improves the quality of information sensing during pulsed field ablation by reducing interference from tissue-ablative pulses, enhancing the accuracy of lesion monitoring and procedure efficiency.

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    Figure CA2025051645_18062026_PF_FP_ABST
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Abstract

A medical system may be configured to cause a first transducer set located on a catheter device to participate in delivering at least one pulse train of pulsed field ablation energy to tissue within a body of a patient (e.g., a bodily cavity), the at least one pulse train comprising a plurality of pulses, each pulse in the plurality of pulses configured to cause irreversible electroporation of tissue; and to cause a second transducer set located on the catheter device to initiate and conclude each sampling of a plurality of samplings during the delivery of the at least one pulse train, each sampling of the plurality of samplings initiated and concluded during a respective interval of time in which no pulsed field ablation energy is delivered within the body of the patient (e.g., the bodily cavity).
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