A washing method enabling multiple use of resins in extraction chromatography

The washing method optimizes acid solutions and sequences to extend the life of LN and DGA columns in radioisotope separation, addressing durability and safety issues, enabling multiple uses and reducing operational complexity and costs.

WO2026142554A1PCT designated stage Publication Date: 2026-07-02CURIUM NUKLEER TIP ANONIM SIRKETI

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
CURIUM NUKLEER TIP ANONIM SIRKETI
Filing Date
2025-03-04
Publication Date
2026-07-02

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Abstract

The invention relates to a washing method in extraction chromatography used in radioisotope separation, which increases the durability of columns by virtue of the solutions used and their amounts, and enables the resins to be used multiple times, n the invention, it has been observed that in LN columns, between 10-100 uses, the resins are chemically and microbially stable, continue their extraction functions, and successfully provide for isotope and / or radioisotope purification and separation. In the washing method according to the invention, the LN column is washed sequentially with 6 M HNO3 and 0.1 M HNO3 solutions and / or the DGA column is washed with a 0.05 M HCI solution.
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