Amino Compound Purification/Separation TRIZ Cases

Hydrosilane reduction replaces flammable hydrogen gas to produce fenfluramine with high purity and minimal metal impurities.

A two-stage hydrogenation process converts dicyanobenzene to xylylenediamine using intermediate separation steps.

A carbazole-based compound fortifies hole transport in organic photoelectric devices.

Adding ammonia creates an amine-rich and acid-rich phase, reducing material loss in aqueous byproducts during isolation.

Segmented fractional condensation isolates high boilers from aniline, reducing thermal stress and energy consumption during purification.

Dual-pressure distillation columns separate phenol from crude aniline using integrated heat transfer between stages.

Supported noble metal catalysis replaces Lewis acid systems, eliminating equipment corrosion and reducing water consumption during synthesis.

Selective precipitation isolates long chain amino acids and dibasic acids from mixed amide derivatives, reducing energy consumption.

Two-stage hydrogenation of phthalonitrile reduces cyanobenzylamine impurities below 0.2 percent, resolving selectivity versus reaction rate trade-offs.

Crystallizing optically active trans-1,2-diaminocyclohexane from azeotropic solvent solutions to isolate high-purity product.

Transition metal catalyst racemizes discarded (S)-enantiomer back to a mixture, boosting overall yield.

Distillation separates 1,4-diaminobutane carbonate and bicarbonate to recover the product while preventing by-product generation.

Adding methanol to aniline purification bottoms prevents high-boiler solidification, reducing losses to 0.8% and avoiding pipeline blockages.

Removing cyclic ketone impurities from the toluenediamine stream prevents color-imparting adduct formation during distillation.

Arylamino compounds reduce crystallization and maintain low operating voltage in thicker hole transport layers.

Evaporation, oxidation, or adsorption removes recalcitrant organics from isophoronediamine wastewater to lower chemical oxygen demand.

Slow cooling rates during crystallization improve optical purity and yield without repeated recrystallization steps.

A rectification column separates N-methylethylenediamine from ethylenediamine using controlled vapor-liquid equilibrium.

Biological production of anthranilate enables thermal decarboxylation to aniline, reducing CO2 emissions from fossil-based synthesis.

Di-, tri- and tetraphenylindane derivatives serve as hole transport materials, resolving synthesis complexity while maintaining high charge mobility.

A continuous process converts monoisopropanolamine with ammonia using a supported heterogeneous hydrogenation catalyst to produce 1,2-propylenediamine.

Segmenting the hole transport layer into p-doped and undoped regions resolves the contradiction between high response rate and low dark current density.

Partial reaction stopping prevents thermodynamic equilibrium, reducing trans-trans isomer formation and boosting catalyst efficiency.

Concentrate fermentation broth then adjust pH to 12 or higher with a base before distilling high-purity 1,4-diaminobutane to eliminate toxic catalysts.

Ruthenium complexes drive dehydrogenative coupling of aminoalcohols, achieving 6.56 wt% capacity without requiring distinct catalysts for opposing steps.

A transaminase biocatalyst converts diastereomeric mixtures into high-purity trans-isomers through dynamic enzymatic isomerization.

Fusing rings restricts rotation to boost quantum yield and oxidation stability in green emission layers.

Simulated moving bed adsorptive technology separates diamines and omega-aminoacids from fermentation mixtures using selective solid adsorbents.

Mandelic acid resolves ivabradine intermediates into diastereomeric salts, achieving 95% enantiomeric purity for industrial synthesis.

Flowing ionic liquids capture sublimated organic gases to enable direct recrystallization without carrier gas exposure.

Segmented zones and ammonia stripping resolve monovalent competition to increase multivalent product purity and concentration.

High concentration NaOH removes phenolics with minimal excess, preventing salt fouling and viscosity spikes during distillation.

A biphenol-based synthesis route produces 3,3′-diaminobenzidine using a combined catalyst system.

Alkaline earth metal ion modification suppresses high-boiling component formation and deactivation during continuous nitro hydrogenation.

A crystalline diethylamine tetrathiomolybdate polymorph enables rapid dissolution in aqueous solutions.

Adding an amine to onium salt mixtures forms a separable amine-carboxylic acid salt, removing acid associates that limit cellulose solubility.

Liquid-phase amination of alcohols with primary amines using copper-based hydrogenation catalysts on oxidic supports.

Dynamic molar ratio adjustment maintains product composition consistency and minimizes by-products when altering production capacity.

Aromatic and ether solvents extract azido-amine derivatives from reaction mixtures.

Ortho-meta substitution on phenolic rings halts aryl-aryl rotation, providing configurational stability that enables efficient enantioselective recognition.

Dry plasma polymerization synthesizes catecholamine thin films, replacing slow aqueous dip-coating to accelerate production rates.

Short residence time distillation removes tetrahydroazepine impurities while minimizing effluent generation and product loss.

Optimized cation compositions and hierarchical porosity in zeolite X adsorbents enhance para-xylene selectivity while resolving prediction difficulties.

Vacuum stripping with steam removes residual unreacted aromatic compounds, ensuring product purity and regulatory compliance.

Reduce mutagenic impurities below 0.5 ppm in bretylium tosylate using acetone and ethyl acetate slurry filtration.

Ether and terpene masking agents eliminate amine odors without compromising chemical stability.

Acid-base inversion transforms fermentation carbonate into pure amine, resolving low yield and salt removal complexity in bioprocessing.