Samples Introduction/Extraction TRIZ Cases

A three-way valve redirects collision gas to vacuum during mode changes, stabilizing chamber pressure and shortening ICP-MS analysis delays.

A permeable passage and closed absorption path suppress dopant vapour leakage while enabling fast IMS doping switches.

Separate liquid channels mix at ejection and collide with porous gas flow to form stable charged droplets for accurate analysis and coating.

A polymer coating turns flaky aerogel into a stronger, low-dust thermal insulator while also reducing fluid flow and power demand.

A spacer-based sample support keeps bonding outgas away from the conductive layer, reducing mass spectrometry noise and sample cross-movement.

Temperature-first parameter optimization in a mass spectrometer improves detection sensitivity while reducing repeated measurements and sample use.

Reference measurements taken before, during, and after parameter sweeps correct signal drift and speed accurate sensitivity tuning.

Acoustic droplet ejection with an open port interface enables fast, contactless mass spectrometry sampling while minimizing contamination.

An ionic liquid matrix using amine and acidic organic ions improves MALDI S/N and resolution for negatively charged synthetic compounds.

A tuned double Wien filter and intermediate lens improve ion transmission and suppress 87Sr/87Rb interference for more accurate isotope ratios.

Pressurized gas drives continuous liquid samples from remote collection to ICP analysis, reducing manual handling and preserving sample integrity.

Selected reinforcement members inside through holes keep thin sample supports from bending or breaking while preserving capillary transport and ionization.

A tuned double Wien filter rejects interfering ions and improves isotope ratio measurement with smaller samples and less chemical cleaning.

A fluid barrier keeps solvent at the coated blade spray tip, reducing corona discharge, unstable spray, and RSD in negative-mode MS.

Feedback-controlled differential pumping keeps ion guide pressure in range to protect pumps while stabilizing ion transmission and declustering.

Controlled molecular micro-flows and ion filtering preserve gas composition fidelity while enabling compact, accurate portable analysis.

Capillary-fed through-holes localize matrix crystallization and preserve sample position, improving MALDI imaging resolution for high-mass samples.

Capillary through holes and conductive surfaces boost sample ion signal intensity while preserving substrate strength for mass spectrometry.

A pressure-driven air core in the transfer conduit speeds open port sample transport for mass spectrometry while improving reproducibility and peak shape.

A charged pretreated substrate lifts hazardous powders without contact and feeds ambient ionization analysis for faster, safer sampling.

Adjacent attracting and repelling magnets stabilize follower motion in a vacuum chamber, reducing start delay and misregistration.

Alternating-field ion guiding boosts chemical ionization at low pressure, improving ultra-trace detection while reducing memory effects.

A polymer coating turns fragile, dusty aerogel into a lightweight thermal insulator that also reduces fluid flow and adds structural strength.

A higher exhaust flow than liquid supply creates a vortex that pulls dispersed airborne sample into the probe for stable collection and analysis.

A vibrating sharp-edge sheath capillary enables voltage-free, low-flow ionization with stable spray and reduced analyte dilution for CE-MS.

Predicted sample intensity sets variable ejection delays to limit carryover interference while preserving mass spectrometry throughput.

Low-power laser tracking of sample transmissivity guides radiant heating stop points for reproducible protein denaturation in MALDI-MS prep.

Accumulating thermally desorbed analyte before ionization avoids gas-flow dilution and sharpens low-level hazardous material detection.

A tapered disposable tip and gantry improve alignment, depth control, and reproducible sample loading into small open port mass spectrometry interfaces.

Periodic bypass purging clears adsorbed water from a CI gas line, improving reagent purity while avoiding continuous gas waste.

Immiscible-fluid circulation inside a capillary extracts and ionizes analytes directly, cutting matrix effects and avoiding separate chromatography.

A porous support with deep, widened holes drains excess liquid while retaining sample position for high-sensitivity imaging mass spectrometry.

A segmented card belt and wiping conveyor automate residue collection while maintaining gas tightness for fast, sensitive card inspection.

Dry-coated tissue is laser ablated into flowing solvent, enabling spatially resolved analysis that separates drugs from metabolites without fragmenting fragile molecules.

Fins, metal foam, and convection replace water cooling in an ICP-MS interface, cutting bulk while limiting ion recombination and clustering.

Multiple analyte detections along the transfer tube measure transit time, improving mass-spectrum to sample-position correlation and fault checks.

Shifting precursor m/z windows across MS cycles separates overlapping ions and improves product-ion deconvolution in tandem mass spectrometry.

Neutral loss scan ratios confirm expected mobile phase solvents before sample introduction, helping catch solvent changes or leaks.

Sodium pyrophosphate extraction with spICP-MS enables accurate Hg nanoparticle size distribution and concentration measurement in complex soils.

A porous probe enables direct microorganism mass spectrometry from raw or complex samples, avoiding pneumatic assistance and lengthy prep.

A jet pump boosts open-port sample flow to the ion source at higher rates with less dilution, improving mass spectrometry throughput and sensitivity.

A coated mesh extraction phase enriches analytes from blood, urine, and food for faster mass spectrometry with lower ion suppression.

Targeted laser ablation guided by defect position enables ICP-MS analysis of ~20 nm semiconductor surface contaminants with less substrate damage.

Through-holes and an adjacent absorbent substrate pull excess sample inward, preventing overflow and preserving ionization efficiency.

Histogram local minimum analysis separates nanoparticle signals from plasma-gas background, improving threshold setting and size distribution accuracy.

Periodic switching between raw and filtered gas streams protects the sensor from silicone oil while maintaining continuous lyophilization monitoring.

Suppressor voltage derivative monitoring detects IC suppressor failure early and stops eluent or switches to water before salts reach the MS.

A coaxial sheath gas flow keeps ions centered in the transfer tube, cutting diffusion losses and improving mass spectrometer sensitivity over longer paths.

A resilient tray support and pressing member let mass spectrometry systems discard used reaction vessels without extra robotic arms or complex control.

Multiple collision energies per precursor window improve DIA deconvolution by linking precursor and product ions in co-eluting spectra.