Surgical Adhesives TRIZ Cases

A sterile air-free bag mixing process enables 30-60% bovine serum albumin solutions with low foam, less denaturation, and lower contamination.

Independent liquid and gas delivery enables reproducible injectable foam while allowing precise adjustment of density, concentration, and volume.

A layered dressing uses a porous matrix, phenol-modified hemostatic layer, and binding layer to seal bleeding fast while degrading safely in vivo.

A decellularized ECM and gelatin bioadhesive improves lung adhesion while staying flexible enough to seal pulmonary air leaks.

A shear-thinning hyaluronic acid-gelatin hydrogel seals needle tracts, stays in place after injection, and lowers pneumothorax risk.

Electrostatically crosslinked hydrogel injects easily, then solidifies in aneurysms to limit recanalization and avoid antiplatelet-related bleeding.

Gas-filled bubble microspheres make implanted hydrogels visible by ultrasound while degrading with the gel to avoid sedimentation and residue risks.

A pH-responsive chitosan bridge enables rapid, strong hydrogel adhesion to tissue without covalent bonding, improving stability in physiological fluids.

Porous HA/β-TCP granules with collagen keep bone putty cohesive while enabling hydration into injectable, non-settable cement or gel.

pH-triggered crosslinking embeds radiocontrast in hydrogel particles, simplifying production and enabling single-syringe injection.

Separate embolic liquids mix only at the target site, enabling in vivo gel formation while preventing off-site embolization from blood dilution.

A porous potassium phosphate slurry balances compressive strength with reabsorption to support bone defects and speed new bone growth.

A composite PLA-PCL film balances tissue fluid absorption with shape stability to prevent warping, detachment, and poor tissue adhesion.

Injectable polysiloxane embolic compositions crosslink in situ to fill difficult vascular spaces while improving tissue support and limiting harm.

A visualization-agent priming approach keeps the embolic agent visible during delivery while reducing post-deployment imaging interference.

Chelated PEG hydrogel maintains wet-state adhesion while enabling controllable gelation, degradation, and bacteriostatic wound closure.

Hydrosilylation-crosslinked silicone PSA balances skin adhesion, moisture resistance, tearability, and biocompatibility for medical use.

A sheath valve and absorbent tip help deliver and mix viscous hemostatic gel evenly at GI tissue sites while reducing injury and procedure time.

Blood-absorbing minisponges expand inside a mesh pouch to compress the uterus, enabling simpler post-partum hemorrhage treatment and removal.

A multilength photo-crosslinkable hyaluronic acid copolymer improves wet tissue adhesion, strength, and elongation without phase separation.

Stable chitosan-kaolin foam adheres to GI mucosa for rapid, prolonged hemostasis where clips or cautery are hard to use.

A light-activated metal-ligand catalyst helps phenol-enriched polymer adhesives crosslink quickly for stronger tissue sealing with less leakage.

Activated ester biocompatible polymers covalently bond to tissue for immediate wound sealing with less trauma than sutures or staples.

A Venturi-mixed two-component spray activates cyanoacrylate at application to seal wounds rapidly without direct contact or premature polymerization.

A hydrocolloid adhesive structure keeps infusion hubs attached for up to 14 days while reducing skin irritation and painful removal.