Unknown Materials TRIZ Cases
- Muse Cell Therapy for Peripheral Blood Flow Reconstruction
SSEA-3-positive Muse cells migrate to ischemic vascular sites, engraft, and rebuild vessels to improve limb blood flow with less invasive treatment.
- Cryopreserved MSC Bone Graft Material for Rapid Bone Regeneration
Cryopreserving MSC-seeded β-TCP bone grafts creates an off-the-shelf implant that cuts preparation time while maintaining cell viability.
- Breast Milk Exosomes for Tumor-Targeted Radioisotope Delivery
NIS-expressing breast milk exosomes carry radioisotopes into tumors, including hypoxic regions, for imaging and localized therapy.
- Dendritic Cell Carriers for Systemic Oncolytic Virus Delivery
Loaded dendritic cells shield oncolytic viruses from antibodies and carry them to tumors, improving systemic delivery and response.
- RBC Membrane-Coated Oncolytic Viruses via Low-Pressure Extrusion
Low-pressure extrusion coats oncolytic viruses with RBC membranes to extend circulation, avoid anti-PEG response, and preserve infectivity.
- Anti-Arrhythmic Drug Combinations for Cardiac Graft Arrhythmia
Combined anti-arrhythmic agents given around cardiac grafting reduce graft-related arrhythmias and support PSC-CM heart therapy.
- Stem Cell Supernatant Fractionation for Cell Activation
Removing sub-3.5 kDa inhibitors from deciduous tooth pulp stem cell supernatant yields a safer, more active cell-activating fraction.
- ECM Particle Biomaterial Crosslinking for Layered Tissue Mimics
Packed acellular ECM particles crosslinked with thiolated polymers form layered tissue mimics without UV damage, supporting repair and 3D culture.
- Herbal Composition for Pleural Effusion Without Repeated Drainage
A multi-herb composition treats pleural effusion by reducing fluid buildup and avoiding repeated drainage that can cause discomfort and lesions.
- FK506-Loaded Nerve Grafts for Sustained Regeneration Support
FK506 is absorbed into nerve graft tissue without hydrogels, enabling sustained release to support regeneration and avoid donor site trauma.
- Antiviral Lozenge Composition for Local SARS-CoV-2 Neutralization
A herbal extract and propolis lozenge targets the mouth and throat to locally neutralize SARS-CoV-2 through synergistic antiviral action.
- Mesenchymal Stromal Cell Therapy for Faster Return to Estrus
Mesenchymal stromal cells promote faster return to estrus in farm animals, dogs, and cats when hormones or feed changes fall short.
- Herbal Supplement Composition for Immune and Metabolic Support
A multi-herb extract composition supports immune function and metabolism in cancer patients while helping reduce nausea, vomiting, and anorexia.
- Equine Mesenchymal Stem Cell Therapy for Insect-Bite Hypersensitivity
Mesenchymal stem cells modulate immune inflammation in horses with insect-bite hypersensitivity, easing pruritus and dermatitis without glucocorticoid harms.
- Room-Temperature Probiotic Beverage Without Sugars or Refrigeration
A clear zero-calorie probiotic drink uses encapsulated Bacillus spores and a stabilizing carrier to stay viable at room temperature.
- Drinkable Whey-Cream Supplement for Appetite-Suppressing Weight Loss
A liquid blend of lactose-free whipping cream, whey isolate, and sugar-free flavoring improves swallowability, absorption, and appetite control.