Magnetic resonance scan control method, graphical user interface device and magnetic resonance imaging system

Abstract

The application relates to a magnetic resonance scan control method, a graphical user interface device system and a magnetic resonance imaging system. An initial positioning image of a magnetic resonance scan is acquired, and an excitation region of a metabolite of interest is selected in the initial positioning image of the magnetic resonance scan. An auxiliary mark is displayed on or around the excitation region of the metabolite of interest, and the auxiliary mark is associated with scan parameters. According to the auxiliary mark, an excitation region of an interfering metabolite is determined. It is judged whether the excitation region of the interfering metabolite exists. If the excitation region of the interfering metabolite does not exist, the magnetic resonance scan is performed by using the scan parameters; otherwise, the auxiliary mark is adjusted until the excitation region of the interfering metabolite does not exist. The magnetic resonance scan control method improves data quality and optimizes the problem that an interfering metabolite is excited due to a chemical shift effect.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical imaging, in particular to a magnetic resonance scanning control method, a graphical user interface device system and a magnetic resonance imaging system. BACKGROUND

[0002] Nuclear magnetic resonance technology uses the resonance effect of radio frequency and proton spin to transfer energy, thereby realizing the signal imaging of protons. Due to the difference in the microenvironment of protons, such as different chemical compositions of different metabolites, the electron cloud density around the protons is different, resulting in some deviation of the resonance frequency. When the main magnetic field is B0, the deviation can be represented as B=B0(1-σ), and the corresponding resonance frequency is changed to v=γ*B0(1-σ), where the unit of v is Hz, γ is the proton gyromagnetic ratio 42.6M*Hz / T, B0 is the main magnetic field strength, and σ is the corresponding chemical shift constant. This change is the chemical shift. The chemical shift is an effect caused by a magnetic field, and the size of the magnetic field is proportional to the applied magnetic field strength. In order to eliminate the numerical representation difference caused by different magnetic field strengths, the chemical shift is defined as: (unit: ppm). This representation eliminates the influence of the applied magnetic field, and under this representation, the relative position of the protons of different metabolites is almost fixed. In magnetic resonance spectroscopy technology, the signal of different metabolites is acquired non-invasively mainly by using the chemical shift characteristics to realize the function of assisting in diagnosing diseases.

[0003] Figure 1 It is the proton imaging detection spectrum of brain neural metabolism. NAA at 2.0 ppm is an important component of synthesized neurons, and when brain lesions involve a large number of damaged neurons, the content of this component will decrease significantly. In the brain neural spectrum, the metabolite signals of interest mainly include NAA at 2.0 ppm, glutamate near 3.0 ppm, Cho at 3.2 ppm, mI near 4.0 ppm, etc. The concentrations of these metabolites are very small relative to the water and fat content of the brain, and often interfere with the data results due to residual water or fat signals. Especially in the area close to the scalp fat, the chemical shift effect often excites the scalp fat and forms strong interference. SUMMARY

[0004] Based on this, the present application provides a magnetic resonance scanning control method, a graphical user interface device system and a magnetic resonance imaging system, which overcome the problem of metabolites being excited due to the chemical shift effect.

[0005] A magnetic resonance scanning control method, comprising:

[0006] acquiring a magnetic resonance scanning initial positioning image;

[0007] selecting an excitation region of a metabolite of interest on the initial scout image of the magnetic resonance scan;

[0008] displaying an auxiliary marker on or around the excitation region of the metabolite of interest, the auxiliary marker being associated with a scan parameter;

[0009] determining an excitation region of an interfering metabolite according to the auxiliary marker;

[0010] determining whether the excitation region of the interfering metabolite contains the interfering metabolite, and if the excitation region of the interfering metabolite does not contain the interfering metabolite, performing the magnetic resonance scan using the scan parameter; otherwise, adjusting the auxiliary marker until the excitation region of the interfering metabolite does not contain the interfering metabolite.

[0011] In one embodiment, the auxiliary marker is a kind and a position of the interfering metabolite that can be excited by the scan parameter.

[0012] In one embodiment, the auxiliary marker is a chemical shift excitation scale.

[0013] In one embodiment, the chemical shift excitation scale is disposed at a corner position of the excitation region of the metabolite of interest.

[0014] In one embodiment, the chemical shift excitation scale has a direction, the scan parameter includes a gradient pulse polarity, and the direction is determined according to the gradient pulse polarity.

[0015] In one embodiment, the adjusting the auxiliary marker includes:

[0016] adjusting the scan parameter;

[0017] updating the auxiliary marker according to the adjusted scan parameter;

[0018] or, rotating the auxiliary marker.

[0019] A graphical user interface apparatus, comprising:

[0020] a medical image data display page for displaying an initial scout image;

[0021] a selection box operable to select an excitation region of a metabolite of interest on the initial scout image;

[0022] an auxiliary marker displayed on or around the selection box for determining an excitation region of an interfering metabolite, the auxiliary marker being associated with a scan parameter.

[0023] In one embodiment, the auxiliary marker also changes a relative position with the selection box in response to a user operation.

[0024] In one of the embodiments, further comprising an adjustment page, the adjustment page comprising:

[0025] a scan parameter display area for displaying the scan parameters;

[0026] a clickable icon for adjusting the scan parameters.

[0027] In one of the embodiments, further comprising:

[0028] a computer system coupled with the MR imaging device and / or the interactive interface, configured to determine an excitation region of the interfering metabolite according to the auxiliary marker, determine whether the excitation region of the interfering metabolite exists the interfering metabolite, send a scan instruction to the MR imaging device in response to the excitation region of the interfering metabolite not existing the interfering metabolite, or send an adjustment instruction to the interactive interface in response to the excitation region of the interfering metabolite existing the interfering metabolite.

[0029] A magnetic resonance imaging system, comprising:

[0030] an MR imaging device configured to acquire an initial scout image of a target object;

[0031] an interactive interface configured to display the initial scout image, display a selected box in response to a user selection on the interactive interface, and display an auxiliary marker in response to a user scan parameter setting on the interactive interface, the auxiliary marker being displayed on or around the selected box, and the auxiliary marker being associated with scan parameters.

[0032] The above-mentioned magnetic resonance scan control method acquires an initial scout image of a magnetic resonance scan, and selects an excitation region of a metabolite of interest in the initial scout image of the magnetic resonance scan. An auxiliary marker is displayed on or around the excitation region of the metabolite of interest, and the auxiliary marker is associated with scan parameters. According to the auxiliary marker, an excitation region of an interfering metabolite is determined. It is determined whether the excitation region of the interfering metabolite exists the interfering metabolite. If the excitation region of the interfering metabolite does not exist the interfering metabolite, the magnetic resonance scan is performed using the scan parameters; otherwise, the auxiliary marker is adjusted until the excitation region of the interfering metabolite does not exist the interfering metabolite. The above-mentioned magnetic resonance scan control method determines the excitation region of the interfering metabolite through the auxiliary marker, and then the excitation of the interfering metabolite is weakened through the process of determination and adjustment, the interference of the interfering metabolite on the metabolite of interest in the excitation region of the metabolite of interest is weakened, and then an optimized magnetic resonance spectrum line is obtained, the data quality is improved, and the problem of the interfering metabolite being excited due to the chemical shift effect is optimized. BRIEF DESCRIPTION OF DRAWINGS

[0033] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the accompanying drawings needed to be used in the embodiments or the prior art description will be briefly introduced as follows. Obviously, the accompanying drawings in the following description only only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained without creative labor based on these drawings.

[0034] Figure 1 The proton imaging detection spectrum of brain nerve metabolism provided for an embodiment of the present application;

[0035] Figure 2 The magnetic resonance scanning control method flowchart provided for an embodiment of the present application;

[0036] Figure 3 The head magnetic resonance spectrum imaging diagram provided for an embodiment of the present application;

[0037] Figure 4 The chemical shift coordinate diagram after changing the left-right direction selection layer gradient polarity provided for an embodiment of the present application;

[0038] Figure 5 The chemical shift coordinate diagram after changing the left-right and up-down selection layer gradient polarity provided for an embodiment of the present application;

[0039] Figure 6 The chemical shift diagram of brain nerve metabolites before adjusting the gradient polarity provided for an embodiment of the present application;

[0040] Figure 7 The chemical shift diagram of brain nerve metabolites after adjusting the gradient polarity provided for an embodiment of the present application;

[0041] Figure 8 The magnetic resonance scanning control system structure diagram provided for an embodiment of the present application;

[0042] Figure 9 The magnetic resonance scanning control method flowchart provided for an embodiment of the present application;

[0043] Figure 10 The magnetic resonance imaging method flowchart provided for an embodiment of the present application;

[0044] Figure 11 The interactive interface diagram of the magnetic resonance imaging system provided for an embodiment of the present application.

[0045] Main element figure number explanation

[0046] 10, region acquisition unit; 20, imaging sequence application unit. DETAILED DESCRIPTION

[0047] In order to make the above objectives, features and advantages of the present application more clear and comprehensible, the specific embodiments of the present application will be described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. However, the present application can be practiced in many different ways from what is described herein, and skilled artisans will be able to make similar modifications to the specific embodiments disclosed without departing from the scope of the present application, and therefore the specific implementations disclosed below are not intended to limit the present application.

[0048] It should be understood that the terms "first", "second" and the like used in the present application can be used herein to describe various elements, but these elements are not limited by these terms. These terms are only used to distinguish the first element from another element. For example, without departing from the scope of the present application, the first acquisition module can be referred to as the second acquisition module, and similarly, the second acquisition module can be referred to as the first acquisition module. The first acquisition module and the second acquisition module are both acquisition modules, but they are not the same acquisition module.

[0049] It should be noted that when an element is referred to as "provided on" another element, it can be directly on the other element or there can be a middle element. When an element is referred to as "connected" to another element, it can be directly connected to the other element or there can be a middle element.

[0050] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present application belongs. The terms used in the specification of the present application are only for the purpose of describing specific embodiments and are not intended to limit the present application. The term "and / or" used herein includes any and all combinations of one or more of the associated listed items.

[0051] In order to solve the problem that the signal of the metabolite of interest is easily affected by interfering metabolites in the existing magnetic resonance spectrum scanning, the present application provides a magnetic resonance scanning method, which comprises: acquiring a magnetic resonance scanning initial positioning image; displaying an auxiliary mark on the magnetic resonance scanning initial positioning image, the auxiliary mark representing the range of two or more metabolites that can be excited under the current scanning parameters; adjusting the current scanning parameters according to the auxiliary mark, so that the magnetic resonance signal collected by the adjusted scanning parameters only contains the component of the metabolite of interest; or, the magnetic resonance signal collected by the adjusted scanning parameters contains the signal component of the metabolite of interest, and the signal component of other non-metabolites of interest / interfering metabolites is suppressed.

[0052] Please refer to Figure 2 The present application provides a magnetic resonance scanning control method. The magnetic resonance scanning control method comprises:

[0053] S10, acquiring a magnetic resonance scan initial positioning image, and determining an excitation region of a metabolite of interest and an excitation region of an interfering metabolite in the magnetic resonance scan initial positioning image;

[0054] S20, applying a radio frequency pulse and a target gradient field to make the excitation region of the interfering metabolite not exist the interfering metabolite. That is, the metabolite of interest falls in the real excitation spatial position, and the interfering metabolite does not fall in the real excitation spatial position. Correspondingly, the magnetic resonance signal collected after the radio frequency pulse and the target gradient field are applied is the signal component of the metabolite of interest, and the signal component of the interfering metabolite is suppressed or even completely eliminated.

[0055] The chemical shift effect causes the real spatial excitation positions of different metabolites to have a certain offset, and the size of the gradient field and the bandwidth of the radio frequency pulse determine the offset distance of the chemical shift. The metabolite of interest region and the interfering metabolite are different kinds of metabolites, and the signal component of the interfering metabolite will affect the magnetic resonance signal collected by the scanning parameters. Ideally, the magnetic resonance signal collected by the scanning parameters should only include the component of the metabolite of interest region. The excitation region of the metabolite of interest refers to the range that can collect the signal component of the metabolite of interest after the initial determination of the scanning parameters; the excitation region of the interfering metabolite refers to the range that can collect the signal component of the interfering metabolite after the initial determination of the scanning parameters; or, the range that can collect the signal component of the interfering metabolite at the same time as collecting the signal component of the metabolite of interest.

[0056] Due to the influence of the chemical shift effect, the excitation region of the metabolite of interest and the excitation region of the interfering metabolite have spatial displacement. In an embodiment, the offset amount dx of the spatial displacement satisfies the following formula Wherein, d f is the difference between the center frequency domain of the interfering metabolite and the center frequency of the metabolite of interest, RF BW is the excitation bandwidth of the radio frequency pulse, and Thickness is the thickness of the scanning layer. The polarity of the gradient pulse determines the direction of the chemical shift; the chemical shift corresponding to a specific metabolite is fixed, and the closed loop circumscribed by the unit axis is the position of the corresponding metabolite being excited.

[0057] Specifically, an initial scan is performed on a target object by using a magnetic resonance (MR) device to obtain an initial data set, an initial scout image is reconstructed according to the initial data set, and an excitation region of a metabolite of interest is determined in the initial scout image. The initial scout image can be a scan scout image, an object contour image, or the like. The excitation region of the metabolite of interest is a region that needs to be observed in detail in the magnetic resonance scan, and can be selected according to actual needs. For example, a user can select and enclose the excitation region of the metabolite of interest by a selection operation. In an embodiment, the excitation region of the metabolite of interest is one of metabolite excitation regions of a liver, a brain ventricle, a prostate, a spinal cord, or the like. The metabolite of interest can be N-acetyl aspartate (NAA), creatine (Cr), choline (Cho), lactic acid (Lac), myo-inositol (mi), glutamine complex (Glx6), or the like. The interfering metabolite can be water, fat, N-acetyl aspartate (NAA), creatine (Cr), choline (Cho), lactic acid (Lac), myo-inositol (mi), glutamine complex (Glx6), or the like, as long as the type of the metabolite of interest is different from that of the interfering metabolite.

[0058] In the human body tissue, voxels generating the interfering metabolite (i.e., the interfering metabolite) are generally around the excitation region of the metabolite of interest or in a boundary region of the excitation region of the metabolite of interest. That is, the excitation region of the metabolite of interest and the spatial position of the interfering metabolite have a correlation relationship. The spatial position of the interfering metabolite for the excitation region of the metabolite of interest can be determined by using the specific position of the excitation region of the metabolite of interest. Furthermore, the excitation region of the interfering metabolite can be determined according to the relative relationship between the excitation region of the metabolite of interest and the position of the interfering metabolite.

[0059] After the excitation region of the metabolite of interest and the excitation region of the interfering metabolite are determined, in order to weaken the interference of the interfering metabolite on the metabolite of interest in the excitation region of the metabolite of interest, excitation of the interfering metabolite can be weakened. At this time, the excitation of the interfering metabolite is weakened by cooperation of a radio frequency pulse and a target gradient field.

[0060] It can be understood that the implementation manner of the step S10 is not specifically limited, as long as the excitation region of the metabolite of interest and the excitation region of the interfering metabolite can be determined in the initial scout image of the magnetic resonance scan.

[0061] In an embodiment, an auxiliary marker is displayed in the initial scout image of the magnetic resonance scan. The auxiliary marker is a chemical shift excitation scale. The step S10 includes:

[0062] A chemical shift excitation scale bar is displayed in the initial localization image of the magnetic resonance scan. The excitation region of the metabolite of interest, carrying the excitation scale, is determined. Based on the relative positions of the excitation region of the metabolite of interest and the positions of interfering metabolites in the initial localization image, the excitation region of the interfering metabolite is determined.

[0063] The chemical shift excitation scale is scaled, and its scale corresponds to the radio frequency pulse gradient. The chemical shift excitation scale can indicate the true excitation spatial location of different chemical shifts. Magnetic resonance images with a chemical shift excitation scale are shown below. Figure 3 As shown, the left image is a head MRI image with a chemical shift excitation scale; the right image is a magnified view of the chemical shift excitation scale. The upper left and lower right corners corresponding to the scale are the diagonal boundaries of the region. In the initial localization image, the excitation profile of the pulse of the excitation region of the metabolite of interest can be obtained based on the excitation region of the metabolite of interest with the excitation scale. In the initial localization image, when the location of an interfering metabolite is within the excitation profile of the pulse of the excitation region of the metabolite of interest, the location of this interfering metabolite is defined as the excitation region of the interfering metabolite. Figure 3 As shown in the right figure, the central region of the excitation area is set to 2 ppm (unit of chemical shift). The closed region formed by this boundary is the excitation region (target excitation region) for the metabolite of interest. If a metabolite corresponds exactly to 2 ppm and is present in this region, the metabolite will be excited. The actual spatial locations of the radio frequency excitation corresponding to the scanning parameters (1 ppm, 2 ppm, 3 ppm, 4 ppm) are distributed along the coordinate axis. The closed regions formed by the upper and lower limits of the scale are the regions where magnetic resonance signal components can be acquired. If an interfering metabolite in the corresponding frequency band is present at this spatial location, the interfering metabolite is excited, and the acquired magnetic resonance signal contains both the signal components of the metabolite of interest and the signal components of the interfering metabolite.

[0064] It is understood that the implementation of step S20 is not specifically limited, as long as the excitation of interfering metabolites can be reduced through the combined effect of radio frequency pulses and target gradient fields.

[0065] In one embodiment, step S20 includes:

[0066] Based on the metabolites in the excitation region of the metabolite of interest, and the relative positional relationship between the excitation regions of the metabolite of interest and the excitation regions of the interfering metabolites, imaging sequence parameters are obtained. Radio frequency pulses and a target gradient field are then applied according to the imaging sequence parameters.

[0067] The imaging sequence parameters include radio frequency pulse parameters and target gradient field parameters. The radio frequency pulse parameters can include a center frequency and a bandwidth. When the center frequency of the radio frequency pulse is set to the chemical shift frequency of a certain metabolite, the corresponding metabolite is the center region of excitation, that is, the prompt box corresponding to the interface is the metabolite (such as the metabolite in the selected box shown in the figure). Figure 3 The excitation positions of other metabolites will be different with different chemical shift deviations. For example, the deviation distance formula conforms to the value described above. The relative deviation of the chemical shifts between metabolites is constant, but the corresponding frequency size will be multiplied with the increase of the B0 field strength. When the radio frequency excitation is fixed, the relative distance deviation will also be multiplied with the increase of the B0 field strength. When the B0 field, the radio frequency pulse parameters and the target gradient field parameters are determined, a real excitation space position and size can be uniquely determined. x

[0068] In one embodiment, the center frequency of the radio frequency pulse is equal to the chemical shift frequency of the metabolite in the excitation region of the metabolite of interest. At this time, the metabolite in the excitation region of the metabolite of interest is the center region of excitation. Since the gradient direction determines the direction of the chemical shift, according to the relative position relationship between the excitation region of the metabolite of interest and the excitation region of the interfering metabolite, the gradient direction of the target gradient field can be changed to change the real excitation space position, and thus the interfering metabolite can be avoided, so that the excitation of the interfering metabolite is not performed or the excitation of the interfering metabolite is weakened.

[0069] The above-mentioned magnetic resonance scan control method obtains a magnetic resonance scan initial positioning image, and selects an excitation region of a metabolite of interest and an excitation region of an interfering metabolite in the magnetic resonance scan initial positioning image. Then, a radio frequency pulse and a target gradient field are applied to make the excitation region of the interfering metabolite not exist the interfering metabolite. The above-mentioned magnetic resonance scan control method realizes the weakening of the excitation of the interfering metabolite through the cooperation of the radio frequency pulse and the target gradient field, weakens the interference of the interfering metabolite on the metabolite of interest in the excitation region of the metabolite of interest, and thus obtains an optimized magnetic resonance spectrum line, improves the data quality, and optimizes the problem of the excitation of the interfering metabolite caused by the chemical shift effect.

[0070] Please refer to Figures 3 to 7 to obtain the brain neural metabolite signal as an example. With 2.0 ppm as the excitation center, the excitation diagonal boundary marks of 0-5 ppm at intervals of 1 ppm are marked in the auxiliary coordinates.

[0071] As Figure 3 ​As shown, the offset distance corresponding to a specific RF generated by 1ppm deviation is determined. With 2.0ppm as the center excitation, the upper and lower boundaries corresponding to the left upper and right lower are given, and the closed region formed by the boundaries is the real excitation region corresponding to 2.0ppm; if a metabolite corresponds to 2.0ppm and there is such a metabolite in the region, the metabolite will be excited, that is, under the default gradient direction, the real spatial position distribution of different frequency excitation with real chemical shift of 1ppm, 2ppm, 3ppm and 4ppm is as shown in Figure 3 As shown, the closed region formed by the upper and lower limits of the scale; if the metabolite of the corresponding frequency band exists at this spatial position, it will be excited. 1.3ppm is the chemical shift position of fat, 1.3ppm is located between 1ppm-2ppm, combined with the positioning image ( Figure 6 ) and the auxiliary coordinate ( Figure 3 right), the excitation region corresponding to 1.3ppm is close to and partially contains the scalp fat, that is, the scalp fat signal is excited. If the left-right direction selection layer gradient polarity is changed, the corresponding left-right direction chemical shift offset direction will change, and the auxiliary coordinate display is as shown in Figure 4 If the polarity of the two selection layer gradients is changed at the same time, the excitation region corresponding to 1.3ppm will shift to the opposite direction, and the adjusted auxiliary coordinate will change to Figure 5 and Figure 7 After adjusting the gradient polarity, the excitation region of 1.3ppm is shown by the dashed box in Figure 7 , and the excitation region is far away from the scalp fat, and the fat interference problem is greatly improved. As shown in Figure 7 , the adjusted fat signal is significantly weakened compared with the adjusted fat signal.

[0072] Please refer to Figure 8 , the application provides a magnetic resonance scan control system. The magnetic resonance scan control system comprises a region acquisition unit 10 and an imaging sequence application unit 20.

[0073] The region acquisition unit 10 is used to acquire a magnetic resonance scan initial positioning image, and to determine an excitation region of a metabolite of interest and an excitation region of an interfering metabolite in the magnetic resonance scan initial positioning image. The imaging sequence application unit 20 is used to apply a radio frequency pulse and a target gradient field, so that the excitation region of the interfering metabolite does not exist the interfering metabolite.

[0074] The above-mentioned magnetic resonance scan control method is a method implemented based on the magnetic resonance scan control system, and as a further improvement of the system, the above-mentioned magnetic resonance scan control method can also be implemented, which will not be described here.

[0075] The magnetic resonance scan control system acquires an initial positioning image of a magnetic resonance scan through the region acquisition unit 10, and determines an excitation region of a metabolite of interest and an excitation region of an interfering metabolite in the initial positioning image of the magnetic resonance scan. Then, the radio frequency pulse and the target gradient field are applied through the imaging sequence application unit 20, so that the excitation region of the interfering metabolite does not exist the interfering metabolite. The magnetic resonance scan control system realizes the weakening of the excitation of the interfering metabolite through the cooperation of the radio frequency pulse and the target gradient field, weakens the interference of the interfering metabolite on the metabolite of interest in the excitation region of the metabolite of interest, and further obtains an optimized magnetic resonance spectrum line, improves the data quality, and optimizes the problem of the excitation of the interfering metabolite caused by the chemical shift effect.

[0076] See Figure 9 The application provides a magnetic resonance scan control method, comprising:

[0077] S100, acquiring an initial positioning image of a magnetic resonance scan;

[0078] S200, selecting an excitation region of a metabolite of interest on the initial positioning image of the magnetic resonance scan;

[0079] S300, displaying an auxiliary mark on or around the excitation region of the metabolite of interest, the auxiliary mark being associated with a scan parameter;

[0080] S400, determining an excitation region of an interfering metabolite according to the auxiliary mark;

[0081] S500, judging whether the excitation region of the interfering metabolite exists the interfering metabolite, if the excitation region of the interfering metabolite does not exist the interfering metabolite, performing a magnetic resonance scan by using the scan parameter; otherwise, adjusting the auxiliary mark until the excitation region of the interfering metabolite does not exist the interfering metabolite.

[0082] An initial data set can be acquired by performing an initial scan on a target object by using a magnetic resonance (MR) device, an initial positioning image is reconstructed according to the initial data set, and an excitation region of a metabolite of interest is determined in the initial positioning image. For example, the initial positioning image can be a scan positioning image, an object contour image, etc. The excitation region of the metabolite of interest is a region that needs to be observed in a magnetic resonance scan. The excitation region of the metabolite of interest can be selected according to actual needs, for example, a user can select and enclose the excitation region of the metabolite of interest by selecting operation. For example, an interactive interface can be set, and a selected box is selected and enclosed on the interactive interface. The region enclosed by the selected box is the excitation region of the metabolite of interest.

[0083] It can be understood that the form of the auxiliary marker is not limited, as long as the auxiliary marker can be associated with the scanning parameter. The auxiliary marker is associated with the scanning parameter can be that the auxiliary marker has a link with the scanning parameter. Alternatively, the auxiliary marker is a chemical shift excitation scale. The chemical shift excitation scale is arranged at a corner position of the to-be-excited region. The chemical shift excitation scale has a direction, the scanning parameter includes a gradient pulse polarity, and the direction of the chemical shift excitation scale is determined according to the gradient pulse polarity. In other embodiments, the auxiliary marker can also be the kind and position of the interfering metabolite that can be excited by the scanning parameter.

[0084] It can be understood that the excitation region of the interfering metabolite can be a region near the excitation region of the metabolite of interest. The excitation region of the interfering metabolite can be selected according to the excitation region of the metabolite of interest with the auxiliary marker. Specifically, in the initial positioning image, the excitation profile of the pulse of the excitation region of the metabolite of interest can be obtained according to the excitation region of the metabolite of interest with the excitation scale. In the initial positioning image, when the position of the interfering metabolite is in the excitation profile of the pulse of the excitation region of the metabolite of interest, the position of the interfering metabolite is defined as the excitation region of the interfering metabolite.

[0085] In one embodiment, adjusting the auxiliary marker includes: adjusting the scanning parameter; and updating the auxiliary marker according to the adjusted scanning parameter.

[0086] In one embodiment, the adjustment of the auxiliary marker can be achieved by rotating the auxiliary marker. The operator rotates the auxiliary marker through the user interface, and at the same time, the scanning parameter associated with the auxiliary marker is also changed.

[0087] Taking the auxiliary marker as a coordinate system with a direction as an example. The scanning parameter can include the polarity of the gradient pulse and the bandwidth of the radio frequency pulse. Among them, the bandwidth of the radio frequency pulse determines the step of the coordinate system as the auxiliary marker; the polarity of the gradient pulse determines the direction of the coordinate system as the auxiliary marker. Adjusting the parameters of the radio frequency pulse and the polarity of the gradient pulse can achieve the adjustment of the auxiliary marker. Similarly, rotating the auxiliary marker can achieve the adjustment of the polarity of the gradient pulse.

[0088] The magnetic resonance scanning control method obtains an initial positioning image of a magnetic resonance scan, and selects an excitation region of a metabolite of interest in the initial positioning image of the magnetic resonance scan. An auxiliary mark is displayed on or around the excitation region of the metabolite of interest, and the auxiliary mark is associated with a scanning parameter. According to the auxiliary mark, an excitation region of an interfering metabolite is determined. It is judged whether the excitation region of the interfering metabolite exists. If the excitation region of the interfering metabolite does not exist, the magnetic resonance scan is performed by using the scanning parameter; otherwise, the auxiliary mark is adjusted until the excitation region of the interfering metabolite does not exist. The magnetic resonance scanning control method determines the excitation region of the interfering metabolite through the auxiliary mark, and then realizes the weakening of the excitation of the interfering metabolite through the judgment and adjustment process, weakens the interference of the interfering metabolite on the excitation region of the metabolite of interest, and then obtains an optimized magnetic resonance spectrum line, improves the data quality, and optimizes the problem of the excitation of the interfering metabolite caused by the chemical shift effect.

[0089] See Figure 10 The application provides a magnetic resonance imaging method. The magnetic resonance imaging method comprises:

[0090] S30, obtaining an initial positioning image of a magnetic resonance scan;

[0091] S40, generating a chemical shift excitation scale in the initial positioning image of the magnetic resonance scan;

[0092] S50, determining an excitation region of the metabolite of interest, and the excitation region of the metabolite of interest carries an excitation scale;

[0093] S60, determining an excitation region of an interfering metabolite according to the relative relationship between the position of the excitation region of the metabolite of interest and the position of the interfering metabolite;

[0094] S70, obtaining an imaging sequence parameter according to the metabolite of the excitation region of the metabolite of interest, and the relative position relationship between the excitation region of the metabolite of interest and the excitation region of the interfering metabolite;

[0095] S80, applying a radio frequency pulse and a target gradient field according to the imaging sequence parameter, so that the excitation region of the interfering metabolite does not exist;

[0096] S90, reconstructing a magnetic resonance signal to obtain a magnetic resonance image of the excitation region of the metabolite of interest.

[0097] The encoding data corresponding to the magnetic resonance signal is filled into the K space. The K space is reconstructed to obtain a magnetic resonance image of the region of interest of the detection object. The magnetic resonance signal is a gradient echo signal.

[0098] The application provides a computer device, comprising a memory and a processor, the memory stores a computer program, and the processor implements the steps of the magnetic resonance scan control method according to any one of the above embodiments when executing the computer program.

[0099] The memory is a computer readable storage medium, which can be used to store software programs, computer executable programs and modules, such as program instructions / modules corresponding to the magnetic resonance scan control method in the embodiments of the application. The processor executes various functional applications and data processing of the device by running the software programs, instructions and modules stored in the memory, that is, implements the above magnetic resonance scan control method.

[0100] The memory can mainly include a program storage area and a data storage area, wherein the program storage area can store an operating system and at least one application required by a function. The data storage area can store data created according to the use of the terminal and the like. In addition, the memory can include a high-speed random access memory, and can also include a non-volatile memory, such as at least one magnetic disk storage device, a flash memory device, or other non-volatile solid-state memory device. In some examples, the memory can further include a memory remotely arranged with respect to the processor, which can be connected to the device through a network. Examples of the above network include but are not limited to the Internet, an intranet, a local area network, a mobile communication network, and a combination thereof.

[0101] The above computer device acquires a magnetic resonance scan initial positioning image, and determines an excitation region of a metabolite of interest and an excitation region of an interfering metabolite in the magnetic resonance scan initial positioning image. Then, a radio frequency pulse and a target gradient field are applied to make the excitation region of the interfering metabolite not exist the interfering metabolite. The above magnetic resonance scan control method realizes the weakening of the excitation of the interfering metabolite through the cooperation of the radio frequency pulse and the target gradient field, weakens the interference of the metabolite of interest in the excitation region of the metabolite of interest caused by the interfering metabolite, and then obtains an optimized magnetic resonance spectrum line, improves the data quality, and optimizes the problem that the interfering metabolite is excited due to the chemical shift effect.

[0102] The application further provides a graphical user interface device. The graphical user interface device comprises a medical image data display page, a selection box and an auxiliary marker.

[0103] The medical image data display page is used to display the initial positioning image. The selected box can be operated to select the excitation region of the metabolite of interest on the initial positioning image. The auxiliary marker is displayed on or around the selected box for determining the excitation region of the interfering metabolite, and the auxiliary marker is associated with the scan parameter. In this embodiment, the auxiliary marker can be associated with the scan parameter in that the auxiliary marker has a directional coordinate system. The scan parameter can include the polarity of the gradient pulse and the bandwidth of the radio frequency pulse. The bandwidth of the radio frequency pulse determines the step of the coordinate system as the auxiliary marker, and the polarity of the gradient pulse determines the direction of the coordinate system as the auxiliary marker. Adjusting the parameters of the radio frequency pulse and the polarity of the gradient pulse can achieve the adjustment of the auxiliary marker. Similarly, rotating the auxiliary marker can achieve the adjustment of the polarity of the gradient pulse.

[0104] In an embodiment, the auxiliary marker changes the relative position with the selected box in response to the user operation.

[0105] In an embodiment, the graphical user interface device further comprises an adjustment page, which comprises a scan parameter display area and a clickable icon.

[0106] The scan parameter display area is used to display the scan parameter. The clickable icon is used to adjust the scan parameter.

[0107] The application also proposes a magnetic resonance imaging system. The magnetic resonance imaging system comprises an MR imaging device and an interactive interface. The MR imaging device is configured to acquire an initial positioning image of a target object. The interactive interface is configured to display the initial positioning image, display a selected box in response to the user selection on the interactive interface, and display an auxiliary marker in response to the scan parameter setting of the user on the interactive interface. The auxiliary marker is displayed on or around the selected box, and the auxiliary marker is associated with the scan parameter.

[0108] In an embodiment, the magnetic resonance imaging system further comprises a computer system. The computer system is coupled with the MR imaging device and / or the interactive interface, and is configured to determine the excitation region of the interfering metabolite according to the auxiliary marker, judge whether the excitation region of the interfering metabolite has the interfering metabolite, send a scan instruction to the MR imaging device in response to the excitation region of the interfering metabolite not having the interfering metabolite, or send an adjustment instruction to the interactive interface in response to the excitation region of the interfering metabolite having the interfering metabolite.

[0109] In an embodiment, the computer system is configured to determine the species and location of metabolites that can be excited by the scan parameters associated with the auxiliary marker; determine whether other non-target metabolites in addition to the target metabolite will be excited based on the auxiliary marker and the species and location of metabolites that can be excited by the scan parameters associated with the auxiliary marker. Further, the computer system is configured to send an adjustment instruction to the interactive interface to cause the magnetic resonance signals acquired by the adjusted scan parameters to contain signal components of the target metabolite and have signal components of other non-target metabolites / interfering metabolites partially or fully suppressed in response to both the target metabolite and the non-target metabolite being excited. Alternatively, the computer system is configured to send a scan instruction to the MR imaging device in response to only the target metabolite being excited. As Figure 11Fig. 11 shows an exemplary user interface of a magnetic resonance imaging system. The user interface 1101 can be composed of a CRT display, an LCD display, an LED display, a 3D display, etc. The user can interact with the user interface 1101 by using a mouse, a touch, a stylus, a keyboard, etc. The interaction can be, for example, selecting a region, clicking an operation to select a tool bar, clicking an operation to enable region editing, etc. The user interface 1101 displays an initial scout image of a target object, which includes three views of a sagittal view, a coronal view and a transverse view. The initial scout image displays a selection box 1102, which can be continuously set by the user using a mouse. The selection box 1102 is provided with a chemical shift excitation scale as an auxiliary marker. A sequence selection area 1103 is provided below the initial scout image. The sequence selection area 1103 can select a sequence type of an imaging scan, such as a gradient echo pulse sequence (GRE), an inversion recovery sequence, an echo planar imaging (EPI), etc. A scan parameter display area 1104 displays scan parameters of the imaging sequence selected by the sequence selection area 1103. The scan parameters can include adjustment parameters of a radio frequency pulse, adjustment parameters of a gradient field, such as a repetition time (TR), an echo time (TE), an inversion time (TI), a number of slices (NSL), an echo train length (ETL), a bandwidth (BW), etc. In this embodiment, the scan parameters of the scan parameter display area 1104 are associated with the selection box 1102 and the chemical shift excitation scale. When the chemical shift excitation scale is adjusted, the associated scan parameters are changed. Alternatively, when the chemical shift excitation scale is rotated, the associated scan parameters are changed. Similarly, when the user clicks the scan parameter display area 1104, the setting box of the scan parameters is in an active state. When the user modifies the scan parameters, the chemical shift excitation scale is also changed accordingly.

[0110] Any combination of the above-described technical features of the embodiments can be made. For the sake of brevity, not all possible combinations of the above-described technical features of the embodiments are described, however, it is to be understood that any combination of the above-described technical features of the embodiments is within the scope of the present disclosure, as long as the combination does not result in a contradiction.

[0111] The above embodiments only express several implementation ways of the present application, and the description is relatively specific and detailed, but it should not be understood as a limitation to the patent scope of the application. It should be pointed out that for ordinary skilled persons in the art, several modifications and improvements can be made without departing from the concept of the present application, which all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application should be subject to the appended claims.

Claims

1. A magnetic resonance scanning control method, characterized in that, include: Acquire the initial localization image for magnetic resonance scanning; Select the excitation region of the metabolite of interest on the initial positioning image of the magnetic resonance scan; An auxiliary marker is displayed on or around the excitation region of the metabolite of interest. The auxiliary marker is linked to the scanning parameters. The auxiliary marker is a chemical shift excitation scale with scale and direction, which indicates the true excitation spatial position of different chemical shifts. The scanning parameters include the bandwidth of the radio frequency pulse, which determines the step size of the coordinate system used as the auxiliary marker. Adjusting the parameters of the radio frequency pulse can adjust the auxiliary marker. The activation region of the interfering metabolite is determined based on the auxiliary markers; Determine whether the excitation region of the interfering metabolite contains the interfering metabolite. If the excitation region of the interfering metabolite does not contain the interfering metabolite, then perform a magnetic resonance scan using the scanning parameters; otherwise, adjust the auxiliary marker until the excitation region of the interfering metabolite does not contain the interfering metabolite.

2. The magnetic resonance scanning control method according to claim 1, characterized in that, The auxiliary markers are the types and locations of interfering metabolites that can be triggered by the scanning parameters.

3. The magnetic resonance scanning control method according to claim 2, characterized in that, The chemical shift excitation scale is positioned at the corner of the excitation region of the metabolite of interest.

4. The magnetic resonance scanning control method according to claim 3, characterized in that... The scanning parameters also include gradient pulse polarity, and the direction of the chemical shift excitation scale is determined based on the gradient pulse polarity.

5. The magnetic resonance scanning control method according to claim 1, characterized in that, The adjustment of the auxiliary marker includes: Adjust the scanning parameters; Update the auxiliary markers based on the adjusted scanning parameters; Alternatively, rotate the auxiliary marker.

6. A graphical user interface device, characterized in that, include: The medical imaging data display page is used to display the initial localization image; The selection box can be manipulated to select the excitation region of the metabolite of interest on the initial positioning image; An auxiliary marker, displayed on or around the selected box, is used to determine the excitation region of interfering metabolites. The auxiliary marker is linked to the scanning parameters and is a chemical shift excitation scale with scale and direction. The chemical shift excitation scale indicates the true excitation spatial position of different chemical shifts. The scanning parameters include the bandwidth of the radio frequency pulse, which determines the step size of the coordinate system used as the auxiliary marker. Adjusting the parameters of the radio frequency pulse can adjust the auxiliary marker.

7. The graphical user interface device according to claim 6, characterized in that, The auxiliary marker also responds to user actions by changing its relative position to the selected box.

8. The graphical user interface device according to claim 6, characterized in that, It also includes an adjustment page, which includes: The scanning parameter display area is used to display the scanning parameters; Clickable icons are used to adjust the scan parameters.

9. The graphical user interface device according to claim 6, characterized in that, Also includes: A computer system, coupled to an MR imaging device and / or an interactive interface, is configured to: determine, based on the auxiliary markers, an excitation region for interfering metabolites; determine whether interfering metabolites are present in the region of the interfering metabolites; and, in response to the absence of interfering metabolites in the excitation region of the interfering metabolites, send a scanning command to the MR imaging device; or, in response to the presence of interfering metabolites in the excitation region of the interfering metabolites, send an adjustment command to the interactive interface.

10. A magnetic resonance imaging system, characterized in that, include: MR imaging equipment is configured to acquire initial localization images of a target object; An interactive interface is configured to display the initial positioning image and to display a selection box in response to a user's selection on the interactive interface. And in response to the user's scanning parameter settings on the interactive interface, an auxiliary marker is displayed. The auxiliary marker is displayed on or around the selected box, and the auxiliary marker is linked to the scanning parameters. The auxiliary marker is a chemical shift excitation scale with scale and direction. The chemical shift excitation scale indicates the actual excitation spatial position of different chemical shifts. The scanning parameters include the bandwidth of the radio frequency pulse. The bandwidth of the radio frequency pulse determines the step size of the coordinate system of the auxiliary marker. Adjusting the parameters of the radio frequency pulse can adjust the auxiliary marker.

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