An objective refraction system and method for determining a refractive state

Abstract

The application provides an objective refraction system and method of refractive state, comprising: a laser light source emitting three beams of blue laser, green laser and infrared laser, an optical beam splitter splitting the three beams into a reference light path and a measurement light path; a plane mirror reflecting the reference light path back to the original path and being received by an interference measurement device; a light adjusting device refracting the measurement light path to realize range measurement of a measurement object, the refracted measurement light path being reflected back to the original path by the measurement object and then being received by the interference measurement device; then, the interference measurement device obtains an interference measurement signal according to the incident measurement light path and the reference light path, a data processing device obtains refractive factor data of the measurement object according to the interference measurement signal, and obtains refractive refraction data of the measurement object according to the refractive factor data. The application can realize the ophthalmic examination that can be completed by multiple devices through one measurement, can quickly understand the real state of the eyeball and judge the myopia condition, and improves the myopia examination efficiency.

Description

Technical Field

[0001] This application relates to the field of optical measurement technology, specifically to an objective optometry system and method for refractive states. Background Technology

[0002] Currently, with the advent of the information age, the trend of myopia occurring at younger ages and at higher levels is very prominent, making eye protection a matter of great concern. Myopia, also known as refractive error, refers to a condition where, when the eye is not using accommodation, parallel light rays, after passing through the eye's refractive system, cannot form a clear image on the retina, but instead form an image in front of or behind the retina.

[0003] The three main factors determining the refractive state of the eye are axial length (AL), lens power (LP), and corneal curvature. By measuring and analyzing the relationship between these three factors, we can obtain data on the eye's refractive state, also known as refractive power. In traditional ophthalmological examinations, corneal refractive power is measured using a corneal refractometer, refractive power is measured using an optometer, and axial length is measured using A-scan ultrasound or an optical coherence biometer.

[0004] Therefore, traditional ophthalmological examinations require multiple examinations using various equipment, which is not conducive to quickly understanding the true state of the eyeball and judging myopia. The numerous examination items result in low efficiency in myopia examinations. Summary of the Invention

[0005] This application provides an objective refraction system and method for refractive status, which can perform an ophthalmological examination that previously required multiple devices in a single measurement. It can quickly understand the true state of the eyeball and determine myopia, thereby improving the efficiency of myopia examination. The technical solution is as follows.

[0006] On the one hand, an objective optometry system for refractive states is provided, the system comprising: a laser source, an optical beam splitter, a plane mirror, a light adjustment device, an interferometric measurement device, and a data processing device;

[0007] The laser source is used to emit three laser beams: blue laser, green laser, and infrared laser.

[0008] The optical beam splitter is used to split the three laser beams into a reference optical path and a measurement optical path;

[0009] The plane mirror is used to reflect the reference light path emitted by the optical beam splitter along its original path; the reflected reference light path is transmitted through the optical beam splitter and received by the interferometric measurement device.

[0010] The light adjustment device is used to refract the measurement light path emitted by the optical beam splitter to realize the range measurement of the object to be measured; the refracted measurement light path is incident on the object to be measured, and after being reflected by the object to be measured, it is received by the interferometric measurement device.

[0011] The interferometric measurement device is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path;

[0012] The data processing device is used to acquire the refractive factor data corresponding to the measured object based on the interferometric measurement signal, and to acquire the refractive optometry data of the measured object based on the refractive factor data.

[0013] In one possible implementation, the refractive factor data includes: corneal thickness, lens thickness, length from the cornea to the center of the macula of the retina, and choroidal thickness.

[0014] In one possible implementation, the light adjustment device employs an array of liquid lenses. By adjusting the positive and negative voltages of the liquid lens array, the refractive index and focal length of the light adjustment device are changed to form concave and convex lenses with different curvatures.

[0015] In one possible implementation, the interferometric measuring device is further used for:

[0016] Based on the principle of optical interference, a corresponding time-domain signal is generated according to the incident measurement optical path and the reference optical path, and the time-domain signal is transformed into a frequency-domain signal to obtain the interferometric measurement signal.

[0017] In one possible implementation, the system further includes a laser fiber coupler disposed between the laser source and the optical beam splitter;

[0018] The laser fiber coupler is used to mix the three laser beams emitted by the laser source into a single fused light source, which is then incident on the optical beam splitter.

[0019] In one possible implementation, the system further includes a laser separation prism disposed between the optical beam splitter and the interferometric measurement device;

[0020] The laser separation prism is composed of three different refractive index media spliced ​​together, and is used to restore the measurement optical path reflected back from the measured object into three laser beams: blue laser, green laser, and infrared laser.

[0021] On the other hand, an objective refraction method for refractive states is provided, the method being executed by a data processing device in an objective refraction system for refractive states, the system further including a laser source, an optical beam splitter, a plane mirror, a light adjustment device, and an interferometric measurement device;

[0022] The laser source is used to emit three laser beams: blue laser, green laser, and infrared laser.

[0023] The optical beam splitter is used to split the three laser beams into a reference optical path and a measurement optical path;

[0024] The plane mirror is used to reflect the reference light path emitted by the optical beam splitter along its original path; the reflected reference light path is transmitted through the optical beam splitter and received by the interferometric measurement device.

[0025] The light adjustment device is used to refract the measurement light path emitted by the optical beam splitter to realize the range measurement of the object to be measured; the refracted measurement light path is incident on the object to be measured, and after being reflected by the object to be measured, it is received by the interferometric measurement device.

[0026] The interferometric measurement device is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path;

[0027] The method includes:

[0028] Based on the interferometric measurement signal, the refractive factor data corresponding to the measured object is obtained, and based on the refractive factor data, the refractive optometry data of the measured object is obtained.

[0029] On the other hand, an objective optometry device for refractive states is provided. The device is applied to a data processing device in an objective optometry system for refractive states. The system also includes a laser source, an optical beam splitter, a plane mirror, a light adjustment device, and an interferometric measurement device.

[0030] The laser source is used to emit three laser beams: blue laser, green laser, and infrared laser.

[0031] The optical beam splitter is used to split the three laser beams into a reference optical path and a measurement optical path;

[0032] The plane mirror is used to reflect the reference light path emitted by the optical beam splitter along its original path; the reflected reference light path is transmitted through the optical beam splitter and received by the interferometric measurement device.

[0033] The light adjustment device is used to refract the measurement light path emitted by the optical beam splitter to realize the range measurement of the object to be measured; the refracted measurement light path is incident on the object to be measured, and after being reflected by the object to be measured, it is received by the interferometric measurement device.

[0034] The interferometric measurement device is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path;

[0035] The device includes:

[0036] The refractive factor data acquisition module is used to acquire the refractive factor data corresponding to the measured object based on the interferometric measurement signal.

[0037] The refractive data acquisition module is used to acquire the refractive data of the measured object based on the refractive factor data.

[0038] In one possible implementation, the refractive data acquisition module includes:

[0039] The choroid thickness acquisition unit is used to acquire historical OCT image data and train a learning model based on the historical OCT image data to obtain the choroid thickness corresponding to each historical OCT image data; the historical OCT image data includes multiple one-to-one corresponding original OCT images, preprocessed OCT images, and OCT images with choroid annotation.

[0040] The ocular multimodal data myopia comparison model construction unit is used to construct an ocular multimodal data myopia comparison model based on the historical OCT image data, the historical refractive factor data corresponding to the historical OCT image data, and the historical refractive optometry data.

[0041] The refractive data acquisition unit is used to input the refractive factor data corresponding to the measured object into the eye multimodal data myopia comparison model to obtain the refractive data of the measured object.

[0042] In one possible implementation, the choroid thickness acquisition unit is further configured to:

[0043] Acquire historical OCT image data and train a learning model based on the historical OCT image data;

[0044] Obtain the initial database for the myopia comparison model; the initial database for the myopia comparison model includes the historical OCT image data, historical refractive factor data (excluding choroidal thickness) corresponding to the historical OCT image data, and historical refractive optometry data;

[0045] The trained learning model is used to process the initial database of the myopia comparison model to obtain the choroidal thickness corresponding to the historical OCT image data, and the choroidal thickness corresponding to the historical OCT image data is recorded in the initial database of the myopia comparison model to form the final database of the myopia comparison model.

[0046] In one possible implementation, the refractive data acquisition unit is further configured to:

[0047] The refractive factor data corresponding to the measured object is input into the ocular multimodal data myopia comparison model, and historical models in the ocular multimodal data myopia comparison model that are the same as or similar to the refractive factor data corresponding to the measured object are obtained;

[0048] Based on the historical refractive data corresponding to the historical model, the refractive data of the measured object are obtained.

[0049] In another aspect, a data processing device is provided, the data processing device including a processor and a memory, the memory storing at least one instruction, the at least one instruction being loaded and executed by the processor to implement the above-described objective refraction method for refractive states.

[0050] In another aspect, a computer-readable storage medium is provided, wherein at least one instruction is stored therein, the at least one instruction being loaded and executed by a processor to implement the above-described objective refraction method for a refractive state.

[0051] The technical solution provided in this application may include the following beneficial effects:

[0052] A laser source emits three laser beams: blue, green, and infrared. An optical beam splitter separates these beams into a reference beam and a measurement beam. A plane mirror reflects the reference beam emitted by the beam splitter back along its original path. The reflected reference beam then passes through the beam splitter and is received by an interferometric measuring device. Simultaneously, a light adjustment device refracts the measurement beam emitted by the beam splitter to measure the range of the object being measured. The refracted measurement beam is incident on the object, reflected back along its original path, and then received by the interferometric measuring device. The interferometric measuring device then acquires an interferometric signal based on the incident measurement and reference beams. A data processing device uses this interferometric signal to obtain the refractive factor data corresponding to the object and, based on this refractive factor data, obtains the refractive optometry data for the object. This method allows for a single ophthalmic examination that would otherwise require multiple devices, providing a rapid understanding of the eye's true condition and assessing myopia, thus improving the efficiency of myopia examinations. Attached Figure Description

[0053] To more clearly illustrate the technical solutions in the specific embodiments of this application or the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0054] Figure 1 This is a schematic diagram of the structure of an objective optometry system for refractive states, according to an exemplary embodiment.

[0055] Figure 2 This is a flowchart illustrating an objective refraction method for refractive states according to an exemplary embodiment.

[0056] Figure 3 This is a schematic diagram of an eyeball measurement frequency domain signal according to an exemplary embodiment.

[0057] Figure 4 This is a schematic diagram illustrating the penetration of lasers of different wavelengths according to an exemplary embodiment.

[0058] Figure 5 This is a structural block diagram of an objective optometry device for refractive states, according to an exemplary embodiment.

[0059] Figure 6 A structural block diagram of a data processing apparatus illustrated in an exemplary embodiment of this application is shown. Detailed Implementation

[0060] The technical solutions of this application will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this application. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0061] It should be understood that in the description of the embodiments of this application, the term "correspondence" may indicate that there is a direct or indirect correspondence between the two, or that there is an association between the two, or that there is a relationship of instruction and being instructed, configuration and being configured, etc.

[0062] Figure 1 This is a schematic diagram illustrating the structure of an objective refraction system according to an exemplary embodiment. The objective refraction system includes: a laser source, an optical beam splitter G1, a plane mirror M2, a light adjustment device R1, an interferometric measurement device L, and a data processing device (…). Figure 1 (Not shown);

[0063] This laser source is used to emit three laser beams: blue laser, green laser, and infrared laser.

[0064] The optical beam splitter G1 is used to split the three laser beams into a reference optical path and a measurement optical path.

[0065] The plane mirror M2 is used to reflect the reference light path emitted by the optical beam splitter G1 along its original path; the reflected reference light path is transmitted through the optical beam splitter G1 and received by the interferometric measurement device L.

[0066] The light adjustment device R1 is used to refract the measurement light path emitted by the optical beam splitter G1 to realize the range measurement of the measurement object M1 (the measurement object M1 can be the center of the eyeball); the refracted measurement light path is incident on the measurement object M1, and after being reflected by the measurement object M1 along the original path, it is received by the interferometric measurement device L.

[0067] The interferometric measurement device L is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path;

[0068] The data processing device is used to acquire the refractive factor data corresponding to the measured object M1 based on the interferometric measurement signal, and to acquire the refractive optometry data of the measured object M1 based on the refractive factor data.

[0069] Furthermore, the laser source emits three laser beams: a blue laser with a wavelength of 450nm, a green laser with a wavelength of 530nm, and an infrared laser with a wavelength of 830nm.

[0070] Furthermore, during the measurement, the optical beam splitter G1 rotates continuously in a circular motion; the interferometric measurement signal is the interferometric measurement signal generated at all positions corresponding to one rotation of the optical beam splitter G1 by the interferometric measurement device L.

[0071] Furthermore, in Figure 1 In the diagram, the dashed line behind the plane mirror M2 and the solid line behind the light adjustment device R1 represent the measuring object M1, and the length h refers to the measured length of the eyeball.

[0072] In one possible implementation, the refractive factor data includes: corneal thickness, lens thickness, length from the cornea to the center of the macula of the retina, and choroidal thickness.

[0073] In one possible implementation, the light adjustment device R1 is an array of liquid lenses. The refractive index and focal length of the light adjustment device R1 are changed by adjusting the positive and negative voltages of the liquid lens array to form concave and convex lenses with different curvatures.

[0074] Furthermore, the light adjustment device R1 consists of an array of miniature liquid lenses. The refractive index and focal length of the liquid lens array can be changed by adjusting the voltage of the positive and negative electrodes, forming concave and convex lenses with different curvatures as needed. The voltage of the liquid lens array is adjusted by a computer program, thereby changing the curvature of the liquid lens array and thus changing the landing point of the emitted light in the measurement optical path, so that the measurement light can measure the object M1 within a certain target range.

[0075] Optionally, the liquid lens array may be without mechanical structure and be operated entirely by electronic control. It has a fast response speed and can quickly change the light path of the measurement optical path to form a measurement matrix within a range, thereby enabling range measurement of the surface of the eyeball (i.e., the aforementioned measurement object M1).

[0076] In one possible implementation, the interferometric measuring device L is also used for:

[0077] Based on the principle of optical interference, a corresponding time-domain signal is generated according to the incident measurement optical path and the reference optical path, and the time-domain signal is transformed into a frequency-domain signal to obtain the interferometric measurement signal.

[0078] Furthermore, the basic principle employed in this embodiment is based on a Michelson interferometer. Therefore, the light rays in both the measurement and reference optical paths are ultimately reflected back to the interferometric measurement device L. According to basic physics, two beams of light with the same frequency, consistent vibration direction, and constant phase difference can interfere. Since the optical beam splitter G1 is a rotating device moving in a circular motion, the interferometric measurement device L can actually obtain the interferometric measurement signals at different time points during one rotation of the optical beam splitter G1 by measuring the differential interference signal. Based on the AD conversion principle, the interferometric measurement device L converts the differential analog signal (i.e., the aforementioned time-domain signal) continuously generated during the rotation of the optical beam splitter G1 into an electrical signal (i.e., the aforementioned frequency-domain signal), and then performs a Fourier transform to provide a frequency-domain signal for analysis.

[0079] Optionally, the interferometric measuring device L is a complete electronic computing unit that can store signals of different wavelengths, different time points, and different locations within a certain time length as needed to form a data structure. By analyzing this data structure, a measurement signal matrix can be formed.

[0080] In one possible implementation, the system further includes a laser fiber coupler C1, which is disposed between the laser source and the optical beam splitter G1.

[0081] The laser fiber coupler C1 is used to mix the three laser beams emitted by the laser source into a single fused light source, which is then incident on the optical beam splitter G1.

[0082] In one possible implementation, the system further includes a laser splitting prism S, which is disposed between the optical beam splitter G1 and the interferometric measuring device L.

[0083] The laser separation prism S is composed of three different refractive index media spliced ​​together, and is used to restore the measurement optical path reflected back by the measured object M1 into three laser beams: blue laser, green laser and infrared laser.

[0084] Furthermore, the laser separation prism S utilizes the characteristic that different wavelengths of laser light produce different refraction angles in different media to reconstruct the mixed 450nm blue laser, 530nm green laser, and 850nm infrared laser into three laser beams of different wavelengths, which are then irradiated onto the interferometric measurement device L. However, during the reconstruction process, due to factors such as the material properties and errors of the laser separation prism S, each beam will experience power attenuation and wavelength tolerance. For example, for a 450nm blue laser, the reconstructed value may be within the range of 450nm ± 15nm.

[0085] In practical applications, the three laser beams emitted by the laser source are mixed into a single beam by the laser fiber coupler C1. There are two optical paths between the source and the interferometric measurement device L: a reference optical path split by the optical beam splitter G1 and a measurement optical path. The reference optical path is reflected by the optical beam splitter G1, incident on the plane mirror M2 above, and then reflected back to the optical beam splitter G1. It then passes through the optical beam splitter G1 and is received by the interferometric measurement device L. The measurement optical path passes through the optical beam splitter G2 and then illuminates the light adjustment device R1. The light adjustment device R1 refracts the measurement optical path, and after refraction, it is incident on the measurement object M1. The light reflected from the measurement object M1 then returns along the original path, passes through the laser separation prism S, which is composed of three different refractive index media, and finally illuminates the interferometric measurement device L.

[0086] Furthermore, the optical beam splitter G1 rotates continuously, emitting synthesized laser light at a certain frequency. Through the light adjustment device R1, the beam of the measurement optical path can illuminate the area of ​​the measurement object M1 (the center of the eyeball), acquiring the backscattered light signals at different measurement positions in this area. Then, the beams of the measurement optical path and the reference optical path enter the interferometric measurement device L together through the laser separation prism S. According to the principle of optical interference, interference fringe patterns are generated at each wavelength and each time inside the interferometric measurement device L. The time-domain pattern of the interference pattern is transformed into a frequency-domain signal using the Fourier transform method, and the interferometric measurement device L collects the relevant signals for calculation.

[0087] Furthermore, such as Figure 1As shown, the objective optometry system also includes an optical beam splitter G2, which is an optical beam splitting device in the measurement optical path. In actual equipment, the part corresponding to the optical beam splitter G2 can be composed of multiple components, which not only undertake the beam splitting function, but also have the function of optical power detection, etc., and can be set according to specific needs.

[0088] The above-described method can measure axial length, corneal refractive power, objective refraction, lens thickness, lens status, and choroidal thickness in a single system or device. This significantly improves examination speed, reduces measurement errors, and better assesses the degree of myopia progression and the effectiveness of myopia treatment interventions. Unlike traditional refraction methods, this method uses lasers of multiple wavelengths to form a scanning matrix to measure corneal refractive power, lens morphology, central and peripheral axial length of the macula, and choroidal thickness. It can calculate the objective refractive status (refraction) of the measured object M1, integrating refraction, biometry, and choroidal thickness measurement into a single instrument for a single measurement. This improves diagnostic efficiency, reduces the number of machines needed to diagnose myopia, and lowers costs.

[0089] In summary, the laser source emits three laser beams: blue, green, and infrared. An optical beam splitter separates these beams into a reference beam and a measurement beam. A plane mirror reflects the reference beam emitted by the beam splitter back along its original path. The reflected reference beam then passes through the beam splitter and is received by the interferometric measurement device. Simultaneously, a light adjustment device refracts the measurement beam emitted by the beam splitter to measure the range of the object being measured. The refracted measurement beam is incident on the object, reflected back along its original path, and then received by the interferometric measurement device. The interferometric measurement device then acquires an interferometric signal based on the incident measurement and reference beams. A data processing device uses this interferometric signal to obtain the refractive factor data corresponding to the object and, based on this refractive factor data, obtains the refractive optometry data for the object. This method allows for a single ophthalmic examination that would otherwise require multiple devices, providing a rapid understanding of the eye's true condition and assessing myopia, thus improving the efficiency of myopia examinations.

[0090] Figure 2 This is a flowchart illustrating an objective refraction method for refractive states according to an exemplary embodiment. The method is executed by a data processing device within an objective refraction system for refractive states, which also includes a laser source, an optical beam splitter, a plane mirror, a light adjustment device, and an interferometric measurement device.

[0091] The laser source is used to emit three laser beams: blue laser, green laser, and infrared laser.

[0092] This optical beam splitter is used to split the three laser beams into a reference optical path and a measurement optical path;

[0093] The plane mirror is used to reflect the reference light path emitted by the optical beam splitter along its original path; the reflected reference light path is transmitted through the optical beam splitter and received by the interferometric measurement device.

[0094] The light adjustment device is used to refract the measurement light path emitted by the optical beam splitter to achieve range measurement of the object being measured; the refracted measurement light path is incident on the object being measured, and after being reflected by the object along the original path, it is received by the interferometric measurement device.

[0095] The interferometric measurement device is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path.

[0096] like Figure 2 As shown, the method may include the following steps:

[0097] S201. Based on the interferometric measurement signal, obtain the refractive factor data corresponding to the measured object.

[0098] In one possible implementation, the interferometric measurement signal is generated by... Figure 1 The refractive factor data, acquired by the interferometric measuring device L, includes corneal morphology, lens refractive morphology, length from the cornea to the center of the macula of the retina, and choroidal thickness.

[0099] Please refer to Figure 3 The diagram illustrates a frequency domain signal for eyeball measurement. For the interferometric signal acquired by the interferometric device L, a Cartier coordinate system is used. The X-axis represents the measured distance (i.e., the distance between the outermost and innermost layers of the eyeball), and the Y-axis represents the intensity of the interferometric signal. The two strongest interferometric signals correspond to the reflection signals from the anterior and posterior surfaces of the cornea and the posterior surface of the retina, respectively. Based on the eye structure, several second-stronger interferometric signals can be obtained, representing the reflection signals from the anterior and posterior surfaces of the lens. The differences between these signals represent the thickness of each tissue. Because red, green, and blue lasers of different wavelengths are used simultaneously to measure the same location on the object, and different wavelengths of laser have different penetrating power (shorter wavelengths have stronger penetration), when the same location is measured by lasers of different wavelengths, the fundus location will generate signals of different depths due to the varying penetration of the lasers. Please refer to... Figure 4 The diagram illustrates laser penetration at different wavelengths. An 830nm signal generates a signal on the fundus surface, a 530nm signal at the optic nerve depth, and a 450nm signal at the choroid depth. By calculating the difference between these three wavelength signals at the same location on the object being measured, the approximate thickness of the choroid can be determined. Then, based on the measurement matrix of the object (via... Figure 1The light adjustment device R1 measures the range of the object being measured, thereby obtaining the calculated data of each point on the measurement matrix. This allows us to know the corneal thickness, corneal curvature, lens thickness, axial length, and choroid thickness data at each point within the central pupil area of ​​the eyeball, i.e., the refractive factor data.

[0100] S202. Based on the refractive factor data, obtain the refractive optometry data of the measured object.

[0101] In one possible implementation, historical OCT image data is acquired, and a learning model is trained based on the historical OCT image data to obtain the choroid thicknesses corresponding to the historical OCT image data; the historical OCT image data includes multiple one-to-one corresponding original OCT images, preprocessed OCT images, and OCT images with choroid annotation.

[0102] Based on the historical OCT image data, the corresponding historical refractive factor data, and the historical refractive optometry data, a multimodal myopia comparison model of the eyeball is constructed.

[0103] The refractive factor data corresponding to the measured object is input into the myopia comparison model of the eye multimodal data to obtain the refractive optometry data of the measured object.

[0104] Furthermore, the historical refractive factor data includes historical corneal thickness, historical lens thickness, historical corneal to macula length, and historical choroid thickness. Therefore, after obtaining the choroid thickness corresponding to the historical OCT image data, and given the historical corneal thickness, historical lens thickness, and historical corneal to macula length, the historical refractive factor data corresponding to the historical OCT image data can be obtained. At this point, based on the historical OCT image data, the historical refractive factor data corresponding to the historical OCT image data, and the historical refractive optometry data (existing data), a multimodal myopia comparison model of the eyeball can be constructed.

[0105] In one possible implementation, historical OCT image data is acquired, and a learning model is trained based on the historical OCT image data.

[0106] Obtain the initial database for the myopia comparison model; the initial database for the myopia comparison model includes the historical OCT image data, the historical refractive factor data (excluding choroidal thickness) corresponding to the historical OCT image data, and the historical refractive optometry data;

[0107] The trained learning model is used to process the initial database of the myopia comparison model to obtain the choroidal thickness corresponding to the historical OCT image data. The choroidal thickness corresponding to the historical OCT image data is then recorded in the initial database of the myopia comparison model to form the final database of the myopia comparison model.

[0108] Furthermore, after training the learning model, an initial database for the myopia comparison model is first constructed. At this stage, since the choroidal thickness corresponding to each historical OCT image data has not yet been calculated, the initial database can only include the historical OCT image data, historical refractive factor data (excluding choroidal thickness) of the historical OCT image data (existing data), and historical refractive error data (existing data). After calculating the choroidal thickness corresponding to each historical OCT image data, each choroidal thickness is recorded in the initial database of the myopia comparison model, resulting in the final database of the myopia comparison model, thus forming a multimodal myopia comparison model. In other words, at this stage, the final database of the myopia comparison model includes historical OCT image data, historical refractive factor data corresponding to the historical OCT image data, and historical refractive error data, namely, corneal refractive power, lens refractive power, refractive error data, axial length, corneal thickness, lens thickness, axial length, OCT image data, and choroidal thickness for each data point.

[0109] In one possible implementation, the refractive factor data corresponding to the measured object is input into the ocular multimodal data myopia comparison model, and historical models in the ocular multimodal data myopia comparison model that are the same as or similar to the refractive factor data corresponding to the measured object are obtained;

[0110] Based on the historical refractive data corresponding to the historical model, obtain the refractive data of the measured object.

[0111] Furthermore, in terms of hardware solutions (i.e.) Figure 1 While the system is being used, a multimodal myopia comparison model for the eyeball is established using deep learning data analysis and computation methods based on historically accumulated clinical data, thereby obtaining the refractive optometry data of the measured object. The specific steps are as follows:

[0112] 1) Acquire raw OCT images (Optical Coherence Tomography) that meet the requirements. Raw OCT images are a type of image data that can be used to examine the thickness of a patient's choroid.

[0113] 2) Preprocess the original OCT image, including thresholding, noise reduction, binarization and other operations, to obtain an image with simplified information (i.e., the preprocessed OCT image).

[0114] 3) Label the choroid location and thickness data of the original OCT images;

[0115] 4) Input the original OCT images, preprocessed OCT images, and OCT images with choroid annotations into a convolutional neural network (CNN) to train the CNN model. The trained CNN model can accurately identify the choroid in the OCT image and calculate its thickness data.

[0116] 5) Construct a myopia comparison model database. Each data point in this database includes corneal refractive power, lens refractive power, refraction data, axial length, corneal thickness, lens thickness, and an OCT image. A trained convolutional neural network (CNN) model is used to process all OCT images in the myopia comparison model database to obtain the choroidal thickness for each data point. The choroidal thickness of each data point is then recorded in the myopia comparison model database to form a multimodal myopia comparison model.

[0117] 6) After the multimodal myopia comparison model of the eyeball is established, the corneal curvature, lens status, central and peripheral axial length of the macula, and choroidal thickness of the measured object can be obtained through a single measurement (i.e., the above refractive factor data). The corneal curvature, lens status, central and peripheral axial length of the macula, and choroidal thickness data are input into the multimodal myopia comparison model of the eyeball as known variables. Through decision tree and logistic regression, a historical model with the same or similar corneal curvature, lens status, central and peripheral axial length of the macula, and choroidal thickness of the measured object can be found in the multimodal myopia comparison model of the eyeball. Through the known corneal refractive power, lens refractive power, and refraction data of the historical model, the refractive refraction data of the measured object corresponding to the current measurement data can be obtained. Thus, it is possible to complete the ophthalmological examination that traditionally requires several devices such as optometry instruments, biometers, and OCT based on a single measurement.

[0118] This method utilizes a sophisticated multimodal myopia comparison model based on deep learning technology to calculate the corneal refractive power, lens refractive power, and refraction data of the measured object. It quantifies the OCT images in traditional myopia examination data, and as the model data improves, it can achieve greater accuracy than traditional examinations.

[0119] In summary, the laser source emits three laser beams: blue, green, and infrared. An optical beam splitter separates these beams into a reference beam and a measurement beam. A plane mirror reflects the reference beam emitted by the beam splitter back along its original path. The reflected reference beam then passes through the beam splitter and is received by the interferometric measurement device. Simultaneously, a light adjustment device refracts the measurement beam emitted by the beam splitter to measure the range of the object being measured. The refracted measurement beam is incident on the object, reflected back along its original path, and then received by the interferometric measurement device. The interferometric measurement device then acquires an interferometric signal based on the incident measurement and reference beams. A data processing device uses this interferometric signal to obtain the refractive factor data corresponding to the object and, based on this refractive factor data, obtains the refractive optometry data for the object. This method allows for a single ophthalmic examination that would otherwise require multiple devices, providing a rapid understanding of the eye's true condition and assessing myopia, thus improving the efficiency of myopia examinations.

[0120] Figure 5 This is a structural block diagram illustrating an objective optometry device for refractive states according to an exemplary embodiment. The device is used as a data processing apparatus in an objective optometry system for refractive states, which also includes a laser source, an optical beam splitter, a plane mirror, a light adjustment device, and an interferometric measurement device.

[0121] The laser source is used to emit three laser beams: blue laser, green laser, and infrared laser.

[0122] This optical beam splitter is used to split the three laser beams into a reference optical path and a measurement optical path;

[0123] The plane mirror is used to reflect the reference light path emitted by the optical beam splitter along its original path; the reflected reference light path is transmitted through the optical beam splitter and received by the interferometric measurement device.

[0124] The light adjustment device is used to refract the measurement light path emitted by the optical beam splitter to achieve range measurement of the object being measured; the refracted measurement light path is incident on the object being measured, and after being reflected by the object along the original path, it is received by the interferometric measurement device.

[0125] The interferometric measurement device is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path;

[0126] The device includes:

[0127] The refractive factor data acquisition module 501 is used to acquire the refractive factor data corresponding to the measured object based on the interferometric measurement signal.

[0128] The refractive data acquisition module 502 is used to acquire the refractive data of the object being measured based on the refractive factor data.

[0129] In one possible implementation, the refractive data acquisition module 502 includes:

[0130] The choroid thickness acquisition unit is used to acquire historical OCT image data and train a learning model based on the historical OCT image data to obtain the choroid thickness corresponding to each historical OCT image data. The historical OCT image data includes multiple one-to-one corresponding original OCT images, preprocessed OCT images, and OCT images with choroid annotation.

[0131] The ocular multimodal data myopia comparison model construction unit is used to construct an ocular multimodal data myopia comparison model based on the historical OCT image data, the historical refractive factor data corresponding to the historical OCT image data, and the historical refractive optometry data.

[0132] The refractive data acquisition unit is used to input the refractive factor data corresponding to the measured object into the myopia comparison model of the eye multimodal data in order to obtain the refractive data of the measured object.

[0133] In one possible implementation, the choroid thickness acquisition unit is further configured to:

[0134] Acquire historical OCT image data and train a learning model based on this historical OCT image data;

[0135] Obtain the initial database for the myopia comparison model; the initial database for the myopia comparison model includes the historical OCT image data, the historical refractive factor data (excluding choroidal thickness) corresponding to the historical OCT image data, and the historical refractive optometry data;

[0136] The trained learning model is used to process the initial database of the myopia comparison model to obtain the choroidal thickness corresponding to the historical OCT image data. The choroidal thickness corresponding to the historical OCT image data is then recorded in the initial database of the myopia comparison model to form the final database of the myopia comparison model.

[0137] In one possible implementation, the refractive data acquisition unit is further configured to:

[0138] Input the refractive factor data corresponding to the measured object into the myopia comparison model of the eye multimodal data, and obtain the historical models in the myopia comparison model that are the same as or similar to the refractive factor data corresponding to the measured object;

[0139] Based on the historical refractive data corresponding to the historical model, obtain the refractive data of the measured object.

[0140] In summary, the laser source emits three laser beams: blue, green, and infrared. An optical beam splitter separates these beams into a reference beam and a measurement beam. A plane mirror reflects the reference beam emitted by the beam splitter back along its original path. The reflected reference beam then passes through the beam splitter and is received by the interferometric measurement device. Simultaneously, a light adjustment device refracts the measurement beam emitted by the beam splitter to measure the range of the object being measured. The refracted measurement beam is incident on the object, reflected back along its original path, and then received by the interferometric measurement device. The interferometric measurement device then acquires an interferometric signal based on the incident measurement and reference beams. A data processing device uses this interferometric signal to obtain the refractive factor data corresponding to the object and, based on this refractive factor data, obtains the refractive optometry data for the object. This method allows for a single ophthalmic examination that would otherwise require multiple devices, providing a rapid understanding of the eye's true condition and assessing myopia, thus improving the efficiency of myopia examinations.

[0141] Figure 6 This illustration shows a structural block diagram of a data processing device according to an exemplary embodiment of this application. The data processing device includes a memory and a processor. The memory stores a computer program, which, when executed by the processor, implements the aforementioned objective refraction method for refractive states.

[0142] The processor can be a central processing unit (CPU). It can also be other general-purpose processors, digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, or combinations thereof.

[0143] Memory, as a non-transitory computer-readable storage medium, can be used to store non-transitory software programs, non-transitory computer-executable programs, and modules, such as the program instructions / modules corresponding to the methods in the embodiments of this invention. The processor executes various functional applications and data processing by running the non-transitory software programs, instructions, and modules stored in the memory, thereby implementing the methods described in the above embodiments.

[0144] The memory may include a program storage area and a data storage area. The program storage area may store the operating system and applications required for at least one function; the data storage area may store data created by the processor, etc. Furthermore, the memory may include high-speed random access memory and non-transitory memory, such as at least one disk storage device, flash memory device, or other non-transitory solid-state storage device. In some embodiments, the memory may optionally include memory remotely located relative to the processor, which can be connected to the processor via a network. Examples of such networks include, but are not limited to, the Internet, corporate intranets, local area networks, mobile communication networks, and combinations thereof.

[0145] One embodiment of this application also provides a computer storage medium for storing a computer program, which, when executed by a processor, implements the above-described objective refraction method for refractive states.

[0146] Those skilled in the art will understand that all or part of the processes in the above-described embodiments can be implemented by a computer program instructing related hardware. The program can be stored in a computer-readable storage medium, and when executed, it can include the processes of the embodiments described above. The storage medium can be a magnetic disk, optical disk, read-only memory (ROM), random access memory (RAM), flash memory, hard disk drive (HDD), or solid-state drive (SSD), etc.; the storage medium can also include combinations of the above types of memory.

[0147] Although embodiments of the invention have been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the invention, and such modifications and variations all fall within the scope defined by the appended claims.

Claims

1. An objective refraction system for refractive states, characterized in that, The system includes: a laser source, an optical beam splitter, a plane mirror, a light adjustment device, an interferometric measurement device, and a data processing device; The laser source is used to emit three laser beams: blue laser, green laser, and infrared laser. The optical beam splitter is used to split the three laser beams into a reference optical path and a measurement optical path; The plane mirror is used to reflect the reference light path emitted by the optical beam splitter along its original path; the reflected reference light path is transmitted through the optical beam splitter and received by the interferometric measurement device. The light adjustment device is used to refract the measurement light path emitted by the optical beam splitter to realize the range measurement of the object to be measured; the refracted measurement light path is incident on the object to be measured, and after being reflected by the object to be measured, it is received by the interferometric measurement device. The interferometric measurement device is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path; The data processing device is used to acquire refractive factor data corresponding to the measured object based on the interferometric measurement signal, and to acquire refractive optometry data of the measured object based on the refractive factor data. The system further includes: a laser fiber coupler, which is disposed between the laser source and the optical beam splitter; the laser fiber coupler is used to mix the three laser beams emitted by the laser source into a fused light source, which is then incident into the optical beam splitter; The system further includes a laser separation prism, which is positioned between the optical beam splitter and the interferometric measurement device. The laser separation prism is composed of three different refractive index media spliced ​​together, and is used to restore the measurement optical path reflected back from the measured object into three laser beams: blue laser, green laser, and infrared laser.

2. The system according to claim 1, characterized in that, The refractive factor data include: corneal thickness, lens thickness, length from the cornea to the center of the macula of the retina, and choroidal thickness.

3. The system according to claim 1, characterized in that, The light adjustment device uses an array of liquid lenses. By adjusting the positive and negative voltages of the liquid lens array, the refractive index and focal length of the light adjustment device are changed to form concave and convex lenses with different curvatures.

4. The system according to claim 1, characterized in that, The interferometric measuring device is also used for: Based on the principle of optical interference, a corresponding time-domain signal is generated according to the incident measurement optical path and the reference optical path, and the time-domain signal is transformed into a frequency-domain signal to obtain the interferometric measurement signal.

5. An objective refraction method for refractive states, characterized in that, The method is performed by a data processing device in an objective optometry system in a refractive state, the system further comprising a laser source, an optical beam splitter, a plane mirror, a light adjustment device, an interferometric measurement device, a laser fiber coupler, and a laser separation prism; The laser source is used to emit three laser beams: blue laser, green laser, and infrared laser. The optical beam splitter is used to split the three laser beams into a reference optical path and a measurement optical path; The plane mirror is used to reflect the reference light path emitted by the optical beam splitter along its original path; the reflected reference light path is transmitted through the optical beam splitter and received by the interferometric measurement device. The light adjustment device is used to refract the measurement light path emitted by the optical beam splitter to realize the range measurement of the object to be measured; the refracted measurement light path is incident on the object to be measured, and after being reflected by the object to be measured, it is received by the interferometric measurement device. The interferometric measurement device is used to acquire interferometric measurement signals based on the incident measurement optical path and the reference optical path; The laser fiber coupler is used to mix the three laser beams emitted by the laser source into a single fused light source, which is then incident on the optical beam splitter. The laser separation prism is used to restore the measurement optical path reflected back from the measured object into three laser beams: blue laser, green laser, and infrared laser. The method includes: Based on the interferometric measurement signal, the refractive factor data corresponding to the measured object is obtained, and based on the refractive factor data, the refractive optometry data of the measured object is obtained.

6. The method according to claim 5, characterized in that, The step of obtaining the refractive optometry data of the measured object based on the refractive factor data includes: Historical OCT image data is acquired, and a learning model is trained based on the historical OCT image data to obtain the choroid thickness corresponding to each historical OCT image data; the historical OCT image data includes multiple one-to-one corresponding original OCT images, preprocessed OCT images, and OCT images with choroid annotation; Based on the historical OCT image data, the historical refractive factor data corresponding to the historical OCT image data, and the historical refractive optometry data, an ocular multimodal data myopia comparison model is constructed. The refractive factor data corresponding to the measured object is input into the ocular multimodal data myopia comparison model to obtain the refractive optometry data of the measured object.

7. The method according to claim 6, characterized in that, The step of acquiring historical OCT image data and training a learning model based on the historical OCT image data to obtain the choroid thicknesses corresponding to the historical OCT image data includes: Acquire historical OCT image data and train a learning model based on the historical OCT image data; Obtain the initial database for the myopia comparison model; the initial database for the myopia comparison model includes the historical OCT image data, historical refractive factor data (excluding choroidal thickness) corresponding to the historical OCT image data, and historical refractive optometry data; The trained learning model is used to process the initial database of the myopia comparison model to obtain the choroidal thickness corresponding to the historical OCT image data, and the choroidal thickness corresponding to the historical OCT image data is recorded in the initial database of the myopia comparison model to form the final database of the myopia comparison model.

8. The method according to claim 7, characterized in that, The step of inputting the refractive factor data corresponding to the measured object into the ocular multimodal data myopia comparison model to obtain the refractive optometry data of the measured object includes: The refractive factor data corresponding to the measured object is input into the ocular multimodal data myopia comparison model, and historical models in the ocular multimodal data myopia comparison model that are the same as or similar to the refractive factor data corresponding to the measured object are obtained; Based on the historical refractive data corresponding to the historical model, the refractive data of the measured object are obtained.

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