Phase offset calibration method for instantaneous position of field-free point in magnetic particle imaging

By acquiring and modulating magnetic particle response signals and current intensity signals, and combining automatic phase modulation and eigenvalue solving, automatic phase calibration of the instantaneous position of a point without a magnetic field is achieved. This solves the problems of large workload and complicated adjustment in existing technologies, and provides a simplified calibration method and clear evaluation criteria.

CN116930843BActive Publication Date: 2026-05-29BEIHANG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIHANG UNIV
Filing Date
2023-07-18
Publication Date
2026-05-29

AI Technical Summary

Technical Problem

Existing methods for calibrating the phase shift of instantaneous positions of points without magnetic fields in magnetic particle imaging require individual measurement or calculation of each device in the MPI device, resulting in a large workload, long calibration time, and complicated adjustments, and lack of clear evaluation criteria.

Method used

A phase offset calibration method for the instantaneous position of a point without a magnetic field in magnetic particle imaging is adopted. By acquiring the magnetic particle response signal and current intensity signal of the target sample, and combining them with the set modulation parameters, the phase is automatically modulated to obtain the target feature value and phase offset. The automatic phase modulation process curve is plotted and the optimal solution is solved to realize the automatic phase calibration of the instantaneous position.

Benefits of technology

It reduces the difficulty of phase modulation, simplifies the operation process, provides clear evaluation criteria and a visualized calibration process, is suitable for calibration of one-dimensional and three-dimensional MPI systems, and has strong scalability.

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Abstract

The present application belongs to the technical field of magnetic particle imaging, and particularly relates to a phase offset calibration method for the instantaneous position of a magnetic field-free point in magnetic particle imaging, aiming to solve the problem that the existing phase offset calibration method for the instantaneous position of a magnetic field-free point requires separate measurement or calculation for each device in the MPI device, resulting in a large workload, a long calibration process time and troublesome adjustment. The method comprises: collecting magnetic particle response signals and current intensity signals as input signals; based on the input signals, cyclically automatically modulating the phase of the instantaneous position of the magnetic field-free point in the imaging process of the MPI device; after the automatic phase modulation is completed, solving the optimal solution of the phase offset; and based on the optimal solution of the phase offset, again automatically modulating the phase of the instantaneous position of the magnetic field-free point in the MPI device to obtain the final instantaneous position and instantaneous speed after phase offset calibration. The present application does not require setting of hardware, greatly reduces the difficulty of phase modulation and facilitates personnel operation.
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Citation Information

Patent Citations

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