Integrated deuterium-hydrogen double nuclear magnetic resonance coil

Abstract

The invention provides an integrated deuterium-hydrogen double nuclear magnetic resonance coil, which comprises a barrel and a plurality of single-channel double-frequency coils, and is characterized in that the barrel is of a hollow barrel-shaped structure; a plurality of single-channel double-frequency coils are overlapped and laid on the outer surface of the cylinder in a surrounding manner; each single-channel double-frequency coil comprises a coil unit, a first capacitor C1, a second capacitor C2, an input and output matching circuit and a double-frequency switching circuit, the first capacitor C1 and the second capacitor C2 are connected to the coil unit in series, and the double-frequency switching circuit is connected to the two ends of the second capacitor C2 in parallel. And the input and output matching circuit is connected to the two ends of the first capacitor C1 in parallel so as to correspondingly match the input and output of the working frequencies of the two coils. According to the invention, the integrated deuteron and hydrogen core dual-frequency working mode switching is realized through the same wiring structure, and the mutual influence caused by repeated positioning of a plurality of coils and multi-structure nesting is avoided.

Description

Technical Field

[0001] The invention relates to the technical field of magnetic resonance imaging, and in particular to an integrated deuterium-hydrogen dual-nuclear magnetic resonance coil. Background Art

[0002] Magnetic resonance imaging (MRI) is non-invasive and non-radioactive, and is widely used in clinical medical disease diagnosis, especially in the imaging of central nervous system diseases such as stroke. Central nervous system diseases such as stroke often undergo early functional metabolic changes and later structural changes, requiring accurate and rapid imaging for early diagnosis and treatment planning.

[0003] deuterium( 2 Deuterium metabolic imaging (DMI) is an emerging tissue metabolic imaging method based on magnetic resonance spectroscopy (MRS) detection of deuterium-labeled compounds (most commonly glucose). Deuterium metabolic imaging can provide additional metabolic and biochemical information for stroke detection and has important potential in stroke diagnosis. Revealing information on brain energy metabolism can provide detailed information about the location, size, morphology of stroke and the involvement of surrounding tissues, which is helpful for early detection and quantitative evaluation of stroke infarct tissue. Deuterium metabolic imaging can measure the aerobic metabolism and glycolysis capacity of stroke infarct tissue, and infarct tissue usually has abnormal glycolysis metabolism, so it can help distinguish lesions from healthy tissues, which is of great significance for early diagnosis. Deuterium metabolic imaging usually needs to be used together with hydrogen nuclear imaging. There are two types of existing magnetic resonance coils. One is to make deuterium and hydrogen nuclear imaging coils separately. When using them, the coils need to be replaced for separate scanning and the patient needs to be repeatedly positioned, which is very inconvenient and difficult to ensure the accurate overlap of the two nuclear scanning positioning. At the same time, this method is more difficult to apply because stroke patients have poor tolerance and cooperation. Another method is to nest the deuterium and hydrogen nuclear imaging coils designed separately. Although this solution avoids repeated patient positioning, the nested structure of the two coils is more complicated, and the two coils interfere with each other, affecting the accuracy and stability of their respective work, and ultimately affecting the quality of the scanning signal and the diagnosis results.

[0004] That is, how to provide a new integrated deuterium-hydrogen dual-nuclear magnetic resonance coil for integrated realization of two operating frequencies of deuterium and hydrogen nuclei to avoid the mutual influence caused by repeated positioning of multiple coils and multi-structure nesting is a technical problem that needs to be solved urgently in this field. Summary of the invention

[0005] In view of the above problems, the present invention aims to provide an integrated deuterium-hydrogen dual nuclear magnetic resonance coil to solve at least one of the above technical problems.

[0006] In order to at least solve the above technical problems, the present invention provides an integrated deuterium hydrogen dual nuclear magnetic resonance coil, the integrated deuterium hydrogen dual nuclear magnetic resonance coil comprising:

[0007] A cylinder and a plurality of single-channel dual-frequency coils, wherein the cylinder is a hollow cylindrical structure; the plurality of single-channel dual-frequency coils are overlapped and laid around the outer surface of the cylinder;

[0008] Each of the single-channel dual-frequency coils includes a coil unit, a first capacitor C1, a second capacitor C2, an input-output matching circuit and a dual-frequency switching circuit. The first capacitor C1 and the second capacitor C2 are connected in series to the coil unit. The dual-frequency switching circuit is connected in parallel to both ends of the second capacitor C2 so that the coil operating frequency can be switched between the magnetic resonance frequency of the deuterium nucleus and the magnetic resonance frequency of the hydrogen nucleus through the dual-frequency switching circuit. The input-output matching circuit is connected in parallel to both ends of the first capacitor C1 so that the input and output of the two coil operating frequencies can be matched correspondingly through the input-output matching circuit.

[0009] Preferably, the dual-frequency switching circuit includes:

[0010] A third capacitor C3, one end of the third capacitor C3 is connected to one end of the second capacitor C2;

[0011] A first switch diode D1, wherein an anode of the first switch diode D1 is connected to the other end of the third capacitor C3, and a cathode of the first switch diode D1 is connected to the other end of the second capacitor C2.

[0012] Preferably, the input-output matching circuit comprises:

[0013] a fourth capacitor C4, one end of the fourth capacitor C4 being connected to one end of the first capacitor C1;

[0014] a fifth capacitor C5, one end of the fifth capacitor C5 is connected to the other end of the first capacitor C1, and the other end of the fifth capacitor C5 and the other end of the fourth capacitor C4 constitute the input and output ends of the single-channel dual-frequency coil;

[0015] a second switch diode D2, wherein the anode of the second switch diode D2 is respectively connected to one end of the fifth capacitor C5 and the other end of the first capacitor;

[0016] A sixth capacitor C6, one end of the sixth capacitor C6 is connected to the cathode of the second switch diode D2, and the other end of the sixth capacitor C6 is connected to the other end of the fifth capacitor C5.

[0017] Preferably, a control voltage is applied to both ends of the first switch diode D1 and the second switch diode D2, respectively, so as to control the conduction and cutoff of the first switch diode D1 and the second switch diode D2 respectively through the applied control voltage.

[0018] Preferably, when the first switch diode D1 is controlled to be turned off by the control voltage, the third capacitor C3 is not connected to the circuit, and the single-channel dual-frequency coil operates at the magnetic resonance frequency of hydrogen nuclei;

[0019] When the first switch diode D1 is controlled to be turned on by the control voltage, the third capacitor C3 is connected to the circuit, and the single-channel dual-frequency coil operates at the magnetic resonance frequency of the deuterium nucleus.

[0020] Preferably, the first capacitor C1, the second capacitor C2 and the coil unit form a single-channel coil loop, and a partial overlapping area is formed between the single-channel coil loops of every two adjacent single-channel dual-frequency coils.

[0021] Preferably, the capacitance values ​​of the first capacitor C1, the second capacitor C2, the third capacitor C3, the fourth capacitor C4 and the area size of the partially overlapping region between each two adjacent single-channel dual-frequency coils are simulated and calculated by an electromagnetic field simulation calculation method.

[0022] Preferably, the integrated deuterium hydrogen dual nuclear magnetic resonance coil is suitable for nuclear magnetic resonance detection of multiple body parts, including the head, body, ankles, knees, and wrists.

[0023] Preferably, the single-channel coil loop is in a circular, polygonal or other irregular shape.

[0024] Preferably, the cylinder is made of a flexible circuit board.

[0025] Beneficial effects:

[0026] The present invention provides a novel integrated deuterium hydrogen dual-nuclear magnetic resonance coil, comprising: a cylinder and a plurality of single-channel dual-frequency coils, wherein the cylinder is a hollow cylindrical structure; the plurality of single-channel dual-frequency coils are overlapped and laid around the outer surface of the cylinder to form a magnetic resonance detection area in the hollow area of ​​the cylindrical structure, and each two adjacent single-channel dual-frequency coils are partially overlapped, so as to achieve the purpose of reducing the influence of coupling between channels; each single-channel dual-frequency coil comprises a coil unit, a first capacitor C1, a second capacitor C2, an input-output matching circuit and a dual-frequency switching circuit, wherein the first capacitor C1 is a first capacitor C2, an input-output matching circuit is a second capacitor C2, and ... C1 and the second capacitor C2 are connected in series on the coil unit, and the dual-frequency switching circuit is connected in parallel to both ends of the second capacitor C2, so that the coil operating frequency can be switched between the magnetic resonance frequency of the deuterium nucleus and the magnetic resonance frequency of the hydrogen nucleus through the dual-frequency switching circuit. The input-output matching circuit is connected in parallel to both ends of the first capacitor C1, so that the input and output of the two coil operating frequencies can be matched correspondingly through the input-output matching circuit, thereby achieving the technical effect of integrated deuterium nucleus and hydrogen nucleus dual-frequency working mode switching through the same set of wiring structures, avoiding the mutual influence caused by repeated positioning of multiple coils and nested structures.

[0027] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention, it can be implemented according to the contents of the specification. In order to make the above and other purposes, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the embodiments of this specification or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0029] Figure 1 A schematic diagram of the structure of the integrated deuterium-hydrogen dual nuclear magnetic resonance coil provided in Example 1;

[0030] Figure 2 A schematic diagram of the structure of a single-channel dual-frequency coil provided in Example 1;

[0031] Figure 3 A simplified structural diagram of a single-channel dual-frequency coil provided in Example 1;

[0032] Figure 4 A simplified structural diagram of a plurality of single-channel dual-frequency coils arranged in a single layer provided in Embodiment 1;

[0033] Figure 5This is a simplified structural diagram of a double-layer arrangement of a plurality of single-channel dual-frequency coils provided in Example 1.

[0034] Reference numerals;

[0035] 1. Cylinder;

[0036] 2. Single channel dual frequency coil;

[0037] 21. Coil unit;

[0038] 22. Input and output matching circuit;

[0039] 23. Dual-frequency switching circuit. DETAILED DESCRIPTION

[0040] The following will be combined with the drawings in the embodiments of this specification to clearly and completely describe the technical solutions in the embodiments of this specification. Obviously, the described embodiments are only part of the embodiments of this specification, not all of the embodiments. Based on the embodiments in this specification, all other embodiments obtained by ordinary technicians in this field belong to the scope of protection of the present invention; the "and / or" keyword involved in this implementation represents both and, or. In other words, A and / or B mentioned in the embodiments of this specification represent both A and B, and A or B, and describe the three states of A and B. For example, A and / or B means: only A is included but not B; only B is included but not A; A and B are included.

[0041] Meanwhile, in the embodiments of this specification, when a component is considered to be "connected" to another component, it may be directly connected to the other component or there may be a central component at the same time. When a component is considered to be "set on" another component, it may be directly set on the other component or there may be a central component at the same time.

[0042] The following describes the embodiments of the present invention through specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed in various ways based on different viewpoints and applications without departing from the spirit of the present invention.

[0043] Embodiment 1

[0044] See also Figure 1-2The first embodiment of the present invention provides an integrated deuterium-hydrogen dual-nuclear magnetic resonance coil, comprising: a cylinder and a plurality of single-channel dual-frequency coils, wherein the cylinder is a hollow cylindrical structure; the plurality of single-channel dual-frequency coils are overlapped and laid around the outer surface of the cylinder; each single-channel dual-frequency coil comprises a coil unit, a first capacitor C1, a second capacitor C2, an input-output matching circuit and a dual-frequency switching circuit, wherein the first capacitor C1 and the second capacitor C2 are connected in series to the coil unit, the dual-frequency switching circuit is connected in parallel to both ends of the second capacitor C2, so as to switch the coil operating frequency between the magnetic resonance frequency of the deuterium nucleus and the magnetic resonance frequency of the hydrogen nucleus through the dual-frequency switching circuit, and the input-output matching circuit is connected in parallel to both ends of the first capacitor C1, so as to match the input and output of the two coil operating frequencies correspondingly through the input-output matching circuit.

[0045] The embodiment of the present invention provides a novel integrated deuterium hydrogen dual-nuclear magnetic resonance coil, comprising: a cylinder and a plurality of single-channel dual-frequency coils, wherein the cylinder is a hollow cylindrical structure; the plurality of single-channel dual-frequency coils are overlapped and laid around the outer surface of the cylinder to form a magnetic resonance detection area in the hollow area of ​​the cylindrical structure, and each two adjacent single-channel dual-frequency coils are partially overlapped, thereby achieving the purpose of reducing the influence of coupling between channels; each single-channel dual-frequency coil comprises a coil unit, a first capacitor C1, a second capacitor C2, an input-output matching circuit and a dual-frequency switching circuit, wherein the first A capacitor C1 and a second capacitor C2 are connected in series to the coil unit, a dual-frequency switching circuit is connected in parallel to both ends of the second capacitor C2, so that the coil operating frequency is switched between the magnetic resonance frequency of the deuterium nucleus and the magnetic resonance frequency of the hydrogen nucleus through the dual-frequency switching circuit, and an input-output matching circuit is connected in parallel to both ends of the first capacitor C1, so that the input and output of the two coil operating frequencies are matched correspondingly through the input-output matching circuit, thereby achieving the technical effect of realizing integrated deuterium nucleus and hydrogen nucleus dual-frequency working mode switching through the same set of wiring structures, avoiding the mutual influence caused by repeated positioning of multiple coils and nesting of multiple structures.

[0046] Because, when two adjacent single-channel dual-frequency coils are partially overlapped and arranged, and the area of ​​the overlapping region is of an appropriate value, the magnetic flux passing in and out of a single-channel coil loop in the plane formed by the other single-channel coil loop is exactly offset, that is, the mutual inductance between the two loops is zero, thereby achieving the effect of zero mutual coupling, thereby achieving the technical effect of simplifying and replacing the decoupling circuits between the channels.

[0047] In a possible implementation, Figure 2 As shown, the dual-frequency switching circuit involved in the present application includes a third capacitor C3 and a first switching diode D1, one end of the third capacitor C3 is connected to one end of the second capacitor C2; the positive electrode of the first switching diode D1 is connected to the other end of the third capacitor C3, and the negative electrode of the first switching diode D1 is connected to the other end of the second capacitor C2.

[0048] Specifically, a circuit formed by connecting the third capacitor C3 and the first switching diode D1 in series is connected in parallel at both ends of the second capacitor C2, and the conduction and cutoff of the first switching diode D1 in the circuit are controlled to achieve switching of different coil operating frequencies, that is, switching between the magnetic resonance frequency of deuterium nuclei and the magnetic resonance frequency of hydrogen nuclei.

[0049] In a possible implementation, Figure 2 As shown, the input-output matching circuit involved in the present application includes a fourth capacitor C4, a fifth capacitor C5, a second switching diode D2 and a sixth capacitor C6, one end of the fourth capacitor C4 is connected to one end of the first capacitor C1; one end of the fifth capacitor C5 is connected to the other end of the first capacitor C1, and the other end of the fifth capacitor C5 and the other end of the fourth capacitor C4 constitute the input and output ends of the single-channel dual-frequency coil; the positive electrode of the second switching diode D2 is respectively connected to one end of the fifth capacitor C5 and the other end of the first capacitor; one end of the sixth capacitor C6 is connected to the negative electrode of the second switching diode D2, and the other end of the sixth capacitor C6 is connected to the other end of the fifth capacitor C5.

[0050] It can be understood that by connecting an input-output matching circuit in parallel at both ends of the first capacitor C1, the input-output matching circuit matches the input and output of the two coil operating frequencies, so that the coil works in the best working state. The coil unit, the first capacitor C1, the second capacitor C2, the fourth capacitor C4 and the fifth capacitor C5 form a radio frequency coil circuit.

[0051] Specifically, the other end of the fourth capacitor C4 and the other end of the fifth capacitor C5 constitute the input and output ends of the single-channel dual-frequency coil, and are connected to an external input and output switching control circuit through the input and output ends. The input and output switching control circuit is a general solution for a transceiver shared coil and can be implemented using existing technology. In actual use, the input and output ends can be used to receive input of a radio frequency pulse signal, and can also output the collected spatial magnetic resonance signal from human tissue.

[0052] In a possible implementation manner, the first capacitor C1, the second capacitor C2 and the coil unit form a single-channel coil loop, and a partial overlapping area is formed between the single-channel coil loops of every two adjacent single-channel dual-frequency coils.

[0053] Specifically, the coil unit of the present application is generally composed of a copper strip, and the first capacitor C1, the second capacitor C2 and the coil unit form a single-channel coil loop to generate distributed inductance in a portion of the coil unit connected between one end of the first capacitor C1 and one end of the second capacitor C2 and another portion of the coil unit connected between the other end of the first capacitor C1 and the other end of the second capacitor C2, thereby forming a series resonance at the magnetic resonance operating frequency.

[0054] In a possible implementation, a control voltage is applied to both ends of the first switch diode D1 and the second switch diode D2, respectively, so as to control the on and off of the first switch diode D1 and the second switch diode D2 respectively through the applied control voltage.

[0055] Specifically, a positive and negative DC voltage may be applied to both ends of the first switch diode D1 to control the conduction and cutoff of the first switch diode D1 by the applied positive and negative DC voltage. Similarly, a positive and negative DC voltage may be applied to both ends of the second switch diode D2 to control the conduction and cutoff of the second switch diode D2 by the applied positive and negative DC voltage, thereby realizing the respective control of the conduction and cutoff of the first switch diode D1 and the second switch diode D2. Among them, the method of controlling the conduction and cutoff of a diode by generating a positive and negative DC voltage can be realized by using the existing technology, and can be specifically set according to actual needs.

[0056] Further, when the first switch diode D1 is controlled to be cut off by the control voltage, the third capacitor C3 is not connected to the circuit, and the single-channel dual-frequency coil operates at the magnetic resonance frequency of the hydrogen nucleus; when the first switch diode D1 is controlled to be turned on by the control voltage, the third capacitor C3 is connected to the circuit, and the single-channel dual-frequency coil operates at the magnetic resonance frequency of the deuterium nucleus.

[0057] Specifically, the present invention adds a first switch diode D1 while connecting a third capacitor C3 in parallel to the second capacitor C2, and controls the first switch diode D1 to be turned on and off, so as to switch between different operating frequencies of the coil. When an external control voltage turns off D1, C3 is not connected to the circuit, and the coil works at the magnetic resonance frequency of hydrogen nuclei; when an external control voltage turns on D1, C3 is connected to the circuit, and the resonant frequency of the coil drops to the magnetic resonance frequency of deuterium nuclei.

[0058] Similarly, by controlling the conduction and cut-off of the second switch diode D2, the input and output matching circuits of the deuterium nucleus and the hydrogen nucleus can be adjusted respectively. Figure 1 The single-channel dual-frequency coil shown can determine the capacitance value of the sixth capacitor C6 and its relationship with the input and output matching circuits of the deuterium nucleus and the hydrogen nucleus according to simulation calculation and debugging, and can be controlled by the conduction and cutoff of D2.

[0059] In a possible implementation, the capacitance values ​​of the first capacitor C1, the second capacitor C2, the third capacitor C3, and the fourth capacitor C4 and the area of ​​the partially overlapping region between each two adjacent single-channel dual-frequency coils are simulated and calculated by an electromagnetic field simulation calculation method.

[0060] In order to achieve the required operating frequency and the optimal decoupling state between channels, electromagnetic field simulation calculations (such as finite element, time-domain finite difference, etc.) can be used to obtain data corresponding to each capacitance value and the area of ​​the partial overlapping area between each channel, and then debugging can be performed based on the actual production samples to obtain the final optimal value.

[0061] In a possible implementation, the integrated deuterium hydrogen dual nuclear magnetic resonance coil involved in the present application is suitable for nuclear magnetic resonance detection of multiple body parts, including the head, body, ankles, knees, and wrists.

[0062] In a possible implementation, the shape of the single-channel coil loop may be set to be circular, polygonal or other irregular shapes.

[0063] like Figure 1-5 As shown, the shape of the single-channel coil loop of the present application is set to a symmetrical octagonal structure. The shape of the single-channel coil loop can also be set to a circular, quadrilateral, hexagonal, polygonal, irregular shape, etc. Figure 3 It is the equivalent octagonal shape of a single-channel coil loop. Every two adjacent single-channel coil loops achieve decoupling between coils by overlapping a part of the area. Then the layout distance between every two single-channel coil loops can be calculated based on the area of ​​the partially overlapping area. It can be preliminarily determined based on the electromagnetic field simulation calculation results, and then adjusted to the optimal value according to the debugging results after actual production. The overlapping method can be adopted as follows Figure 4 The single layer overlap shown and Figure 5 The double-layer overlapping method shown is implemented, and the specific details can be determined according to the coil size, usage location and shape.

[0064] For example, when the shape of the single-channel coil loop is a circle and the diameter of the circle is 1 distance unit, it can be calculated that the centers of the two single-channel coil loops are 0.75 distance units apart, and thus the layout distance between every two single-channel dual-frequency coils is 0.75 distance units; when the shape of the single-channel coil loop is a square and the side length of the square is 1 distance unit, it can be calculated that the centers of the two single-channel coil loops are 0.9 distance units apart, and thus the layout distance between every two single-channel dual-frequency coils is 0.9 distance units.

[0065] In a possible embodiment, the hollow cylindrical cylinder can be made of a flexible circuit board, and the hollow area of ​​the cylinder is used to detect human tissue, so as to collect magnetic resonance signals from human tissue through the deuterium hydrogen dual nuclear magnetic resonance coil provided in this application. In addition, the size of the cylinder and the deuterium hydrogen dual nuclear magnetic resonance coil and the overlapping setting mode of the single-channel coil loop in the deuterium hydrogen dual nuclear magnetic resonance coil can be set according to the corresponding human tissue to be used, and then can be used for nuclear magnetic resonance detection of various parts of the body such as the head, body, ankle, knee, wrist, etc. The cylinder can also use a hollow structure in a position without coil wiring according to different application parts. Several single-channel dual-frequency coils can be arranged on the outer surface of the cylinder by pasting. The coil unit of the single-channel dual-frequency coil can also be connected in series with other capacitors in the series circuit of the coil unit, the first capacitor C1 and the second capacitor C2 according to actual needs.

[0066] In a possible implementation, the integrated deuterium hydrogen dual nuclear magnetic resonance coil provided in the present application can be used in a variety of high-field and ultra-high-field magnetic resonance systems such as 3T and 7T.

[0067] According to the reciprocity theorem of coils, this design can be used for magnetic resonance transmitting coils, receiving coils and transmitting-receiving common coils.

[0068] In summary, the integrated deuterium-hydrogen dual nuclear magnetic resonance coil provided by the present application has the following beneficial effects:

[0069] (1) The same wiring structure is used to realize the integrated deuterium and hydrogen dual-frequency working coils, avoiding the mutual influence caused by repeated positioning of multiple coils and multiple structure nesting;

[0070] (2) Using switch electronics to control the switching of operating frequencies can achieve real-time fast switching and support multi-sequence real-time switching scanning;

[0071] (3) Using a multi-channel phased array solution formed by overlapping a number of single-channel dual-frequency coils to achieve decoupling through the overlapping structure between channels and improve the quality of magnetic resonance scanning signals;

[0072] (4) By setting up input and output matching circuits to realize the transmission and reception sharing working mode, the system complexity is reduced, the RF output power is reduced, and the patient's RF absorption rate (SAR) is reduced.

[0073] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the limiting conditions for the implementation of the present invention, so they have no substantial technical significance. Any modification of the structure, change of the proportion relationship or adjustment of the size should still fall within the scope of the technical content disclosed by the present invention without affecting the effects and purposes that can be achieved by the present invention. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" quoted in this specification are only for the convenience of description, and are not used to limit the scope of the implementation of the present invention. The change or adjustment of their relative relationship should also be regarded as the scope of the implementation of the present invention without substantially changing the technical content.

[0074] The above is only a preferred embodiment of the present invention, and does not limit the present invention in any form. Although the present invention has been disclosed as a preferred embodiment as above, it is not used to limit the present invention. Any technician familiar with this profession can make some changes or modifications to equivalent embodiments of equivalent changes using the technical contents disclosed above without departing from the scope of the technical solution of the present invention. However, any simple modification, equivalent change and modification made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. An integrated deuterium hydrogen dual nuclear magnetic resonance coil, characterized in that: The integrated deuterium hydrogen dual nuclear magnetic resonance coil comprises: A cylinder and a plurality of single-channel dual-frequency coils, wherein the cylinder is a hollow cylindrical structure; the plurality of single-channel dual-frequency coils are overlapped and laid around the outer surface of the cylinder; Each of the single-channel dual-frequency coils includes a coil unit, a first capacitor C1, a second capacitor C2, an input-output matching circuit and a dual-frequency switching circuit. The first capacitor C1 and the second capacitor C2 are connected in series to the coil unit. The dual-frequency switching circuit is connected in parallel to both ends of the second capacitor C2 so that the coil operating frequency can be switched between the magnetic resonance frequency of the deuterium nucleus and the magnetic resonance frequency of the hydrogen nucleus through the dual-frequency switching circuit. The input-output matching circuit is connected in parallel to both ends of the first capacitor C1 so that the input and output of the two coil operating frequencies can be matched correspondingly through the input-output matching circuit.

2. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 1, characterized in that: The dual-frequency switching circuit comprises: A third capacitor C3, one end of the third capacitor C3 is connected to one end of the second capacitor C2; A first switch diode D1, wherein an anode of the first switch diode D1 is connected to the other end of the third capacitor C3, and a cathode of the first switch diode D1 is connected to the other end of the second capacitor C2.

3. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 2, characterized in that: The input-output matching circuit comprises: a fourth capacitor C4, one end of the fourth capacitor C4 being connected to one end of the first capacitor C1; a fifth capacitor C5, one end of the fifth capacitor C5 is connected to the other end of the first capacitor C1, and the other end of the fifth capacitor C5 and the other end of the fourth capacitor C4 constitute the input and output ends of the single-channel dual-frequency coil; a second switch diode D2, wherein the anode of the second switch diode D2 is respectively connected to one end of the fifth capacitor C5 and the other end of the first capacitor; A sixth capacitor C6, one end of the sixth capacitor C6 is connected to the cathode of the second switch diode D2, and the other end of the sixth capacitor C6 is connected to the other end of the fifth capacitor C5.

4. The integrated deuterium hydrogen dual nuclear magnetic resonance coil as claimed in claim 3, characterized in that: A control voltage is applied to both ends of the first switch diode D1 and the second switch diode D2 respectively, so as to control the conduction and cutoff of the first switch diode D1 and the second switch diode D2 respectively through the applied control voltage.

5. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 4, characterized in that: When the first switch diode D1 is turned off by the control voltage, the third capacitor C3 is not connected to the circuit, and the single-channel dual-frequency coil operates at the magnetic resonance frequency of hydrogen nuclei; When the first switch diode D1 is controlled to be turned on by the control voltage, the third capacitor C3 is connected to the circuit, and the single-channel dual-frequency coil operates at the magnetic resonance frequency of the deuterium nucleus.

6. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 5, characterized in that: The first capacitor C1, the second capacitor C2 and the coil unit form a single-channel coil loop, and a partial overlapping area is formed between the single-channel coil loops of every two adjacent single-channel dual-frequency coils.

7. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 6, characterized in that: The capacitance values ​​of the first capacitor C1, the second capacitor C2, the third capacitor C3, the fourth capacitor C4 and the area of ​​the partially overlapping region between each two adjacent single-channel dual-frequency coils are simulated and calculated by an electromagnetic field simulation calculation method.

8. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 7, characterized in that: The integrated deuterium hydrogen dual nuclear magnetic resonance coil is suitable for nuclear magnetic resonance detection of multiple body parts, including the head, body, ankles, knees, and wrists.

9. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 8, characterized in that: The single-channel coil loop has a circular, polygonal or other irregular shapes.

10. The integrated deuterium hydrogen dual nuclear magnetic resonance coil according to claim 9, characterized in that: The cylinder is made of a flexible circuit board.

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