Children lung-clearing and asthma-relieving ointment and health-care patch

Through the design of children's lung clearing and asthma ointment and health patch, the use of acupuncture point-based medication, polymer sustained release materials and microcapsules technology, the problem of children's resistance to taking medicine and drugs to stimulate the gastrointestinal tract is solved, and a safe, efficient and long-term therapeutic effect is achieved.

CN120131893APending Publication Date: 2025-06-13LIAONING JIUXUAN PHARMACEUTICAL & HEALTH PRODUCTS CO LTD
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Patent Information

Application Number
CN202510323555.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-19
Publication Date
2025-06-13
Patent Text Reader

Abstract

The invention relates to the technical field of traditional Chinese medicine, and discloses a children lung clearing and asthma relieving ointment and health care patch, the children lung clearing and asthma relieving ointment comprises a front patch and a rear patch, the front patch is used for relieving cough and swelling, the front patch comprises fresh white impatiens balsamina pedicel, fresh burdock rhizome, flaxseed oil, musk and myrrh, and the front patch is prepared from the following components: fresh white impatiens balsamina pedicel, fresh burdock rhizome and flaxseed oil which are fried to be slightly scorched and soaked for 72 hours or more; the herbal medicine ingredients are medical hot melt adhesives and carbon steel balls, the rear patch is used for clearing lung and relieving asthma, the components of the rear patch comprise scutellaria baicalensis, mint, cortex mori radicis, cortex lycii radicis, semen momordicae, ginger powder, ramulus mori, folium eriobotryae, bamboo leaves, cypress leaves, tangerine leaves, pepper, houttuynia cordata, radix isatidis, dandelion full beads and fructus forsythiae, and the herbal medicine ingredients are the medical hot melt adhesives. The front patch is attached to the Danzhong acupoint-Tiantu acupoint, the rear patch is attached to the lung acupoint-Yongquan acupoint, meanwhile, the children are difficult to take medicine, do not enter the mouth and are assisted in fixed-point medicine administration at the acupoints with high safety, the set is used in a matched mode to achieve the directional health care effect, the effect is better, and assistance is provided for the children according to the characteristic that the children are difficult to take medicine.
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Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a children's lung-clearing and asthma-relieving ointment and a health-care patch. Background Art

[0002] Health patches are a common patch product used to improve health, relieve symptoms or promote recovery. They are usually made of medicinal ingredients, plant extracts or natural ingredients, which can be absorbed through the skin and work. The types and uses of health patches are very wide. Children's lung clearing and asthma relieving ointment is usually used to relieve children's lung discomfort caused by colds and coughs, such as sputum, wheezing, and difficulty breathing.

[0003] In the prior art, some drugs are taken orally for treatment. Children have a sensitive sense of taste and the drugs taste bad, which leads to resistance to taking the drugs, affecting the treatment effect. In addition, children's stomachs are relatively fragile, so irritating drugs can easily irritate children's delicate gastrointestinal tract after entering the stomach, causing nausea, vomiting, diarrhea and other adverse reactions. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a children's lung-clearing and asthma-relieving ointment and health-care patch to solve the problems of drug resistance, which affects the treatment effect, and drugs irritating the stomach and intestines, leading to adverse reactions such as nausea, vomiting, and diarrhea.

[0005] To achieve the above objectives, the present invention is implemented through the following technical solutions:

[0006] A children's lung-clearing and asthma-relieving ointment, comprising:

[0007] Front and back stickers;

[0008] The front patch is used for relieving cough and swelling. The front patch ingredients include fresh Impatiens balsamina flower stalks, fresh burdock rhizomes, linseed oil, fried slightly charred and soaked for more than 72 hours, aconite, cassia twig, angelica, cinnamon, aconite, Chuanwu, earthworm, bombyx batryticatus, angelica dahurica, liquorice, bletilla striata, radix striatae, dandelion root, schizonepeta tenuifolia, siler, aconite root, cortex galangae, mint, honeysuckle, forsythia, frankincense, musk, myrrh, and the herbal ingredients are medical hot melt adhesive and carbon steel beads;

[0009] The back patch is used for clearing the lungs and relieving asthma. The ingredients of the back patch include scutellaria baicalensis, mint, mulberry bark, Chinese wolfberry bark, anemarrhena, asparagus, forsythia, perilla, pollen, rutabaga, platycodon, tangerine peel, curcuma, fructus aurantii, arctium, inula flower, angelica dahurica, aristolochia, peucedanum, siler, green peel, arisaema, tetrandra, belamcanda, scutellaria baicalensis, coltsfoot flower, gallnut, yuanshen, radix rehmanniae, licorice, moutan bark, akebia, plantain seed, red peony root, immature bitter orange, whole trichosanthes root, sodium sulfate, momordica charantia, ginger powder, mulberry branch, loquat leaf, bamboo leaf, cypress leaf, tangerine leaf, Zanthoxylum bungeanum, houttuynia cordata, isatis root, whole dandelion, forsythia, and the herbal ingredients are medical hot melt adhesive.

[0010] Preferably, the weights of the materials for the front patch are 10 grams of aconite root, 20 grams of cassia twig, 18 grams of angelica, 15 grams of cinnamon, 20 grams of kusnezoff monkshood root, 20 grams of common monkshood mother root, 20 grams of earthworm, 20 grams of bombyx batryticatus, 20 grams of dahurian angelica root, 30 grams of liquorice, 20 grams of bletilla striata, 20 grams of divaricate saposhnikovia root, 20 grams of dandelion root, 20 grams of asperagus root, 20 grams of ledebouriella root, 20 grams of dung beetle, 20 grams of tangerine peel, 20 grams of mint, 20 grams of honeysuckle flower, 20 grams of forsythia fruit, 9 grams of frankincense, 9 grams of musk, 9 grams of myrrh, and the Chinese herbal medicine configuration ingredients are medical hot melt adhesive and carbon steel beads.

[0011] Preferably, the weights of the materials for the back patch are 30 grams of skullcap root, 15 grams of mint, 20 grams of mulberry bark, 30 grams of cortex lycii radicis, 30 grams of anemarrhena rhizome, 30 grams of asparagus tuber, 30 grams of forsythia fruit, 18 grams of perilla seed, 10 grams of pollen, 15 grams of genkwa flower, 15 grams of platycodon root, 15 grams of tangerine peel, 15 grams of turmeric root-tuber, 15 grams of bitter orange, 15 grams of great burdock achene, 20 grams of inula flower, 20 grams of dahurian angelica root, 20 grams of aristolochia debilis, 20 grams of hogfennel root, 20 grams of ledebouriella root, 20 grams of green tangerine peel, 20 grams of arisaema cum bile, 20 grams of stephania root, 20 grams of belamcanda root, 20 grams of dwarf lilyturf tuber, 20 grams of figwort root, 20 grams of rehmannia root, 30 grams of liquorice, 20 grams of tree peony bark, 20 grams of akebia stem, 20 grams of plantain seed, 20 grams of red peony root, 20 grams of bitter orange, 20 grams of snakegourd fruit, 5 grams of mirabilite, 8 grams of cochinchina momordica seed, 20 grams of ginger powder, 30 grams of mulberry branch, 30 grams of loquat leaf, 30 grams of bamboo leaf, 30 grams of cypress leaf, 30 grams of tangerine leaf, 15 grams of Chinese prickly ash, 30 grams of houttuynia cordata, 30 grams of isatis root, 30 grams of dandelion whole plant, 30 grams of forsythia fruit, and the ingredients are medical hot melt adhesive.

[0012] A children's lung-clearing and asthma-relieving health patch, comprising:

[0013] An ointment layer, a flexible buffer comfort layer, a waterproof and antibacterial composite backing layer, and a precise controlled-release drug penetration layer;

[0014] The ointment layer is made by evenly applying ointment on non-woven fabric;

[0015] The flexible buffer comfort layer is made by mixing a medical-grade gel material with a natural plant extract;

[0016] The waterproof and antibacterial composite backing layer is made by laminating an outer waterproof polyurethane film and an inner antibacterial nano-silver coating;

[0017] The precise controlled-release drug penetration layer is made by using a high-molecular material with a drug slow-release function and microcapsules encapsulating drugs.

[0018] Preferably, the thickness of the ointment in the ointment layer is 0.3 - 0.5 MM, and the thickness of the non-woven fabric is 0.1 - 0.2 MM. A pretreatment step is carried out during application, and the pretreatment step includes degreasing and disinfecting the non-woven fabric.

[0019] Preferably, the medical-grade gel material comprises polyacrylic acid and polyvinyl alcohol, and the ratio of polyacrylic acid to polyvinyl alcohol is 3:2, with a thickness of 0.5-0.8 mm. The natural extract comprises menthol and borneol.

[0020] Preferably, the thickness of the waterproof polyurethane film is 0.05-0.1 mm, the particle size of the nano silver is 20-50 nanometers, and the thickness of the coating is 0.01-0.03 mm.

[0021] Preferably, the polymer sustained-release material comprises hydroxypropyl methylcellulose, and the thickness of the hydroxypropyl methylcellulose is 0.2-0.4 mm. The wall material of the microcapsule comprises gelatin and gum arabic, and the mass ratio of the two is 2:1, with the microcapsule particle size of 10-50 microns.

[0022] The present invention provides a children's lung-clearing and asthma-relieving ointment and health patch, which has the following beneficial effects:

[0023] 1. By using the front patch and the back patch simultaneously, the front patch is applied to the Shanzhong acupoint - Tiantu acupoint, and the back patch is applied to the Feishu acupoint - Yongquan acupoint. The main function of the front patch is to relieve cough and reduce swelling, and the main function of the back patch is to clear the lungs and relieve asthma. The human acupoints have inherent targeting advantages. This patch is used for auxiliary health care during the illness period according to specific acupoints. Considering the difficulty of children taking medicine, without entering the mouth, and high safety, drug-assisted acupoint targeting is carried out, achieving the effect of directional health care. Used as a set, the effect is better, which is an auxiliary for the characteristic of children having difficulty taking medicine.

[0024] 2. Through the combination of the polymer sustained-release material and the microcapsule technology, the multi-stage release and precise controlled release functions of the drug are realized. The active ingredients in the ointment layer penetrate into the skin through the flexible buffer comfort layer. At the same time, the polymer sustained-release material prolongs the drug release time, and the hierarchical release mechanism of the microcapsules ensures that the drug maintains an effective concentration for a long time, so as to be applicable to the treatment scenarios requiring continuous drug efficacy.

[0025] 3. The flexible buffer comfort layer of the present invention is made of a medical-grade gel material, containing polyacrylic acid and polyvinyl alcohol, as well as natural extracts (menthol, borneol), which not only provides good softness and conformability, but also effectively reduces the pressure and irritation of the patch on the skin. At the same time, the cooling and itching-relieving effect brought by the natural extracts significantly improves the experience of long-term use, and is suitable for sensitive people and children. Specific embodiments

[0026] The technical solutions of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the scope of protection of the present invention.

[0027] An embodiment of the present invention provides a children's Qingfei Pingchuan ointment, comprising:

[0028] A front patch and a rear patch;

[0029] The front patch is used for relieving cough and reducing swelling. The components of the front patch include fresh white phoenix flower stalks, fresh burdock rhizomes, linseed oil, fried until slightly charred and soaked for more than 72 hours, aconite, cinnamon twig, angelica, cinnamon, kusnezoff monkshood, common monkshood mother root, earthworm, bombyx batryticatus, dahurian angelica root, licorice root, bletilla striata, Chinese clematis root, dandelion root, dipsacus root, divaricate saposhnikovia root, trogopterus dung, tangerine peel, mint, honeysuckle flower, forsythia, frankincense, musk, myrrh. The herbal ingredients are medical hot melt adhesive and carbon steel beads;

[0030] The rear patch is used for clearing the lungs and relieving asthma. The components of the rear patch include scutellaria baicalensis, mint, mulberry bark, cortex lycii radicis, anemarrhena asphodeloides, asparagus root, forsythia, perilla seed, pollen, genkwa flower, platycodon root, tangerine peel, turmeric root-tuber, bitter orange, burdock fruit, inula flower, dahurian angelica root, aristolochia debilis, common hogfennel root, blackberrylily rhizome, dwarf lilyturf tuber, rehmannia root, licorice root, tree peony bark, akebia stem, plantain seed, red peony root, bitter orange, trichosanthes fruit, mirabilite, momordica cochinchinensis, ginger powder, mulberry branch, loquat leaf, bamboo leaf, cypress leaf, tangerine leaf, Chinese prickly ash, houttuynia cordata, isatis root, dandelion whole plant, forsythia. The herbal ingredients are medical hot melt adhesive.

[0031] The weight of each material in the front patch is 10 grams of aconite, 20 grams of cinnamon twig, 18 grams of angelica, 15 grams of cinnamon, 20 grams of kusnezoff monkshood, 20 grams of common monkshood mother root, 20 grams of earthworm, 20 grams of bombyx batryticatus, 20 grams of dahurian angelica root, 30 grams of licorice root, 20 grams of bletilla striata, 20 grams of Chinese clematis root, 20 grams of dandelion root, 20 grams of dipsacus root, 20 grams of divaricate saposhnikovia root, 20 grams of trogopterus dung, 20 grams of tangerine peel, 20 grams of mint, 20 grams of honeysuckle flower, 20 grams of forsythia, 9 grams of frankincense, 9 grams of musk, 9 grams of myrrh. The herbal ingredients are medical hot melt adhesive and carbon steel beads.

[0032] Specifically, after accurately weighing all herbal raw materials according to the proportion, they are subjected to pretreatment steps such as cleaning, chopping, drying, and pulverizing to ensure the full release of the active ingredients of the medicinal materials. Toxic medicinal materials such as aconite, kusnezoff monkshood, and common monkshood need to be processed through strict traditional processing techniques to ensure their safety while maximizing the retention of their effects of dispelling wind and cold, warming the meridians and relieving pain; warm-natured medicinal materials such as cinnamon twig and cinnamon need to be processed by low-temperature drying to ensure that active ingredients such as volatile oils are not damaged; heat-clearing and detoxifying medicinal materials such as honeysuckle and forsythia are processed through the extraction process of water extraction and alcohol precipitation to ensure the concentration and uniform distribution of their antibacterial and anti-inflammatory active ingredients;

[0033] After the materials are processed, all the dried traditional Chinese medicine powders are mixed evenly, and then an appropriate amount of linseed oil is added as a lubricant, and the mixture is poured into refined medical hot melt adhesive, and continuously stirred until a uniform paste is formed. This medical hot melt adhesive is made of high molecular polymer, has good adhesiveness and biocompatibility, can ensure the close fit of the paste to the skin, and has a synergistic effect on the slow release of drug components. Carbon steel beads are added to the mixed paste to increase the pressure stimulation of local application, so as to promote the absorption of drug components by the skin and improve the clinical efficacy. After stirring evenly, the paste is evenly coated on the pretreated medical non-woven fabric. The non-woven fabric needs to be degreased and sterilized at high temperature before coating to ensure its surface is clean and sterile and has good air permeability. After coating, the paste needs to be naturally dried or dried at low temperature to ensure that the paste is evenly attached to the non-woven fabric without losing its stickiness.

[0034] The finally formed patch has a significant effect of relieving cough and reducing swelling. Through the synergistic effect of traditional Chinese medicine components, it quickly exerts its medicinal effect after application. Components such as aconite, kusnezoff monkshood, and common monkshood can warm the meridians, dispel cold, relieve pain and promote blood circulation to remove stasis, and relieve cough and chest tightness caused by phlegm-dampness blockage in the lungs; honeysuckle and forsythia eliminate inflammation through heat-clearing and detoxifying effects; components such as dandelion root, ledebouriella root, and bletilla striata can promote local blood circulation on the skin surface and enhance the penetration of drug components, so as to better improve respiratory symptoms. The presence of carbon steel beads further stimulates the activity of skin acupoints through physical stimulation and acts together with the drugs to achieve the therapeutic effect.

[0035] The weight of each material applied later is 30 grams of Scutellaria baicalensis, 15 grams of Mentha haplocalyx, 20 grams of Mori Cortex, 30 grams of Lycii Cortex, 30 grams of Anemarrhenae Rhizoma, 30 grams of Asparagi Radix, 30 grams of Forsythiae Fructus, 18 grams of Perillae Fructus, 10 grams of Trichosanthis Radix, 15 grams of Genkwa Flos, 15 grams of Platycodonis Radix, 15 grams of Citri Reticulatae Exocarpium, 15 grams of Curcumae Radix, 15 grams of Aurantii Fructus Immaturus, 15 grams of Arctii Fructus, 20 grams of Inulae Flos, 20 grams of Angelicae Dahuricae Radix, 20 grams of Aristolochiae Fructus, 20 grams of Peucedani Radix, 20 grams of Saposhnikoviae Radix, 20 grams of Citri Reticulatae Viride Pericarpium, 20 grams of Arisaematis Rhizoma, 20 grams of Stephaniae Tetrandrae Radix, 20 grams of Belamcandae Rhizoma, 20 grams of Cynanchi Stauntonii Radix, 20 grams of Tussilaginis Flos, 20 grams of Galla Chinensis, 20 grams of Scrophulariae Radix, 20 grams of Rehmanniae Radix, 30 grams of Glycyrrhizae Radix, 20 grams of Moutan Cortex, 20 grams of Akebiae Caulis, 20 grams of Plantaginis Semen, 20 grams of Paeoniae Radix Rubra, 20 grams of Aurantii Fructus Immaturus, 20 grams of Trichosanthis Fructus, 5 grams of Natrii Sulfas, 8 grams of Momordicae Semen, 20 grams of Zingiberis Rhizoma, 30 grams of Mori Ramulus, 30 grams of Eriobotryae Folium, 30 grams of Bambusae Folium, 30 grams of Biotae Folium, 30 grams of Citri Reticulatae Folium, 15 grams of Zanthoxyli Pericarpium, 30 grams of Houttuyniae Herba, 30 grams of Isatidis Radix, 30 grams of Taraxaci Herba, 30 grams of Forsythiae Fructus, and the ingredient is medical hot melt adhesive.

[0036] Specifically, among the ingredients, herbs such as Scutellaria baicalensis, Mori Cortex, and Forsythiae Fructus are mainly characterized by their heat-clearing and anti-inflammatory effects, which can effectively relieve the heat toxin and inflammation in the lungs; herbs that nourish yin and moisten the lungs, such as Anemarrhenae Rhizoma, Asparagi Radix, Scrophulariae Radix, and Rehmanniae Radix, can regulate the dry symptoms of the respiratory tract and enhance the overall moistening effect of the medicine; cough-relieving and phlegm-dissolving herbs such as Perillae Fructus, Peucedani Radix, and Tussilaginis Flos, combined with Platycodonis Radix and Citri Reticulatae Exocarpium, can accelerate the discharge of phlegm and relieve the blockage of the lungs; Houttuyniae Herba, Isatidis Radix, and Taraxaci Herba further enhance the effect of the medicine through their significant antibacterial and anti-inflammatory effects, thereby eliminating the hidden dangers of respiratory tract infections. In addition, warm or volatile herbs such as Zingiberis Rhizoma, Zanthoxyli Pericarpium, and Mentha haplocalyx can increase the local warm feeling through external application, accelerate blood circulation, and promote the transdermal absorption of the medicine;

[0037] In the drug mixing process, the powders or liquid medicines of the above-mentioned herbs are uniformly mixed in proportion, and medical hot melt adhesive is gradually added and continuously stirred to ensure the full combination of the herbs and the hot melt adhesive. The medical hot melt adhesive is made of polymer materials, has good adhesion and air permeability, and can also be used as a carrier for the medicine to delay the release of the medicine and ensure a long-term effect. The final mixture needs to be slowly dried to a paste state in a low-temperature environment to ensure that the active ingredients are not decomposed due to high temperature;

[0038] Subsequently, the prepared paste-like mixture is evenly coated on the non-woven fabric. The non-woven fabric needs to be pretreated with degreasing, disinfection, etc. before coating to ensure sterility and skin-friendly properties. The coated ointment is cured at room temperature or in a low-temperature drying environment to form a medicated patch;

[0039] When used, it can be directly applied to the relevant acupoints on the back or chest, and the effect of clearing the lungs and relieving asthma is achieved through the contact and penetration of the drug with the skin. Through the synergistic effect of various herbs and combined with the continuous controlled release function of the drug release carrier hot melt adhesive, the patch can maintain the release of the active ingredients of the drug for a long time, further relieve lung inflammation, promote sputum discharge, and enhance respiratory smoothness. In particular, ingredients such as Houttuynia cordata, Isatis indigotica, and whole Dandelion can play a strong anti-inflammatory and antiviral role during the application period, providing a significant effect for the adjuvant treatment of respiratory diseases.

[0040] A children's health care patch for clearing the lungs and relieving asthma, comprising:

[0041] An ointment layer, a flexible buffer comfort layer, a waterproof and antibacterial composite backing layer, and a precise controlled release drug penetration layer;

[0042] The ointment layer is made by evenly applying ointment on non-woven fabric;

[0043] The flexible buffer comfort layer is made by mixing a medical-grade gel material and natural plant extracts;

[0044] The waterproof and antibacterial composite backing layer is made by laminating an outer waterproof polyurethane film and an inner antibacterial silver nano-coating;

[0045] The precise controlled release drug penetration layer is made of a polymer material with a drug slow release function and microcapsules encapsulating the drug.

[0046] The thickness of the ointment in the ointment layer is 0.3 - 0.5 MM, and the thickness of the non-woven fabric is 0.1 - 0.2 MM. A pretreatment step is carried out during the application, and the pretreatment step includes degreasing and disinfecting the non-woven fabric.

[0047] Specifically, it has significant advantages in terms of drug delivery and application experience: the ointment layer ensures the efficient release of drug components, the flexible buffer comfort layer improves the comfort of application, the waterproof and antibacterial composite backing layer provides a protective barrier, and the precise controlled release drug penetration layer achieves a long-term drug slow release effect. The whole set of designs can meet the transdermal absorption requirements of the drugs for clearing the lungs and relieving asthma, and at the same time ensure the safety and comfort during the application process, providing a solid foundation for the clinical application of the present invention.

[0048] The medical-grade gel material includes polyacrylic acid and polyvinyl alcohol, and the ratio of polyacrylic acid to polyvinyl alcohol is 3:2, with a thickness of 0.5 - 0.8 mm. The natural extracts include menthol and borneol.

[0049] Specifically, polyacrylic acid in the medical-grade gel material is a high-molecular compound with excellent hygroscopicity and film-forming properties. It mainly plays the roles of structural support and moisturization, can form a slightly moist environment during the application process, enhance the penetration effect of the drug, and at the same time reduce the skin dryness or discomfort that may be caused by a long application time. Polyvinyl alcohol further enhances the mechanical strength and skin-adhering property of the gel with its flexibility and strong adhesion performance, can ensure the close fit of the flexible buffer comfort layer with the human skin surface, and can achieve an ideal balance among softness, adhesiveness, and breathability. It can not only provide sufficient buffering to relieve the pressure on the skin during application but also ensure breathability and the wearing comfort of the user.

[0050] The introduction of natural extracts menthol and borneol further enhances the drug-assisted function of the flexible buffer comfort layer. Menthol is a component with a cooling sensation and anti-inflammatory effect. By stimulating the nerve endings on the skin surface, it produces a slight cold sensation effect at the application site, helps relieve the discomfort of the local skin, and at the same time can promote local blood circulation and improve the transdermal absorption efficiency of the drug components. Borneol, as a traditional Chinese medicine component, has the effects of opening the orifices and dissipating heat, anti-inflammatory and analgesic. Acting synergistically with menthol, it can significantly enhance the therapeutic effect during the application process.

[0051] The thickness of the waterproof polyurethane film is 0.05 - 0.1 mm, the particle size of the nano silver is 20 - 50 nanometers, and the thickness of the coating is 0.01 - 0.03 mm.

[0052] Specifically, the waterproof polyurethane film, as the outer layer material of the backing layer, has excellent waterproof performance and certain breathability. It can ensure sufficient flexibility of the film while ensuring waterproofness, and will not crack or delaminate due to the application action or user activities. The polyurethane material has good stretchability and ductility, can adapt to the dynamic changes of the human skin, and ensure a fitting state during the application process. The microporous structure of the film provides a certain degree of breathability, can effectively avoid the local stuffiness and skin discomfort caused by long-term application.

[0053] The nano silver coating is the inner layer material of the backing layer. It can not only ensure excellent antibacterial performance but also avoid the instability caused by too small particles or the influence on adhesiveness due to too large particles. The antibacterial mechanism of nano silver mainly kills bacteria, fungi, and some viruses by releasing silver ions and interfering with the metabolic process of microbial cells. This antibacterial performance effectively avoids the risk of bacterial growth or infection during long-term application. The polyurethane film can effectively block the entry of external moisture and liquids, ensure the normal use of the application device in a humid environment. The microporous structure of the film allows water vapor to pass through, avoids the accumulation of heat and humidity on the skin surface, and improves the comfort during the application process. The nano silver coating can continuously release silver ions, kill a variety of pathogenic microorganisms, prevent bacterial growth, and reduce the risk of infection caused by application.

[0054] The polymer sustained-release material includes hydroxypropyl methylcellulose, and the thickness of the hydroxypropyl methylcellulose is 0.2 - 0.4 mm. The wall material of the microcapsule includes gelatin and gum arabic, and the mass ratio of the two is 2:1. The particle size of the microcapsule is 10 - 50 microns.

[0055] Specifically, the polymer sustained-release material selects hydroxypropyl methylcellulose as a semi-synthetic polymer material, which has good biocompatibility and controlled-release performance. It can form a uniform gel layer by swelling with water, thereby regulating the drug release rate, providing sufficient mechanical strength to support the drug loading and sticking requirements, and ensuring that the gel layer maintains appropriate permeability after swelling with water, ensuring the continuous and effective release of drug components during transdermal absorption.

[0056] As the carrier of the drug, the wall material of the microcapsule selects gelatin and gum arabic. Gelatin is used as the main wall material, which has good film-forming property and biodegradability, and can form a stable wall layer structure during the preparation of the microcapsule, ensuring that the drug is not oxidized or degraded during the encapsulation process. As the auxiliary wall material, its ratio with gelatin can further improve the flexibility and mechanical strength of the wall layer, and at the same time endow the microcapsule with good stability and solubility.

[0057] The microcapsule is beneficial to increasing the initial rate of drug release and helping to extend the drug release time, thereby forming a multi-stage controlled-release effect, and can achieve that the drug components have both the ability to take effect quickly and the ability to maintain long-term therapeutic effects during the sticking process.

[0058] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A children's lung-clearing and asthma-relieving ointment, characterized in that: include: Front and back stickers; The front patch is used for relieving cough and swelling. The front patch ingredients include fresh Impatiens balsamina flower stalks, fresh burdock rhizomes, linseed oil, fried slightly charred and soaked for more than 72 hours, aconite, cassia twig, angelica, cinnamon, aconite, Chuanwu, earthworm, bombyx batryticatus, angelica dahurica, liquorice, bletilla striata, radix striatae, dandelion root, schizonepeta tenuifolia, siler, aconite root, cortex galangae, mint, honeysuckle, forsythia, frankincense, musk, myrrh, and the herbal ingredients are medical hot melt adhesive and carbon steel beads; The back patch is used for clearing the lungs and relieving asthma. The ingredients of the back patch include scutellaria baicalensis, mint, mulberry bark, Chinese wolfberry bark, anemarrhena, asparagus, forsythia, perilla, pollen, rutabaga, platycodon, tangerine peel, curcuma, fructus aurantii, arctium, inula flower, angelica dahurica, aristolochia, peucedanum, siler, green peel, arisaema, tetrandra, belamcanda, scutellaria baicalensis, coltsfoot flower, gallnut, yuanshen, radix rehmanniae, licorice, moutan bark, akebia, plantain seed, red peony root, immature bitter orange, whole trichosanthes root, sodium sulfate, momordica charantia, ginger powder, mulberry branch, loquat leaf, bamboo leaf, cypress leaf, tangerine leaf, Zanthoxylum bungeanum, houttuynia cordata, isatis root, whole dandelion, forsythia, and the herbal ingredients are medical hot melt adhesive.

2. A children's lung-clearing and asthma-relieving ointment according to claim 1, characterized in that: The weight of each material of the front patch is 10 grams of aconite, 20 grams of cassia twig, 18 grams of angelica, 15 grams of cinnamon, 20 grams of aconite, 20 grams of aconite, 20 grams of earthworm, 20 grams of bombyx batryticatus, 20 grams of angelica dahurica, 30 grams of liquorice, 20 grams of bletilla striata, 20 grams of radix schizonepetae, 20 grams of dandelion root, 20 grams of intermittent powder, 20 grams of siler, 20 grams of aconite, 20 grams of cortex galangae, 20 grams of mint, 20 grams of honeysuckle, 20 grams of forsythia, 9 grams of frankincense, 9 grams of musk, 9 grams of myrrh, and the Chinese herbal medicine ingredients are medical hot melt adhesive and carbon steel beads.

3. A children's lung-clearing and asthma-relieving ointment according to claim 1, characterized in that: The weight of each material of the back patch is 30 grams of scutellaria, 15 grams of peppermint, 20 grams of mulberry bark, 30 grams of lycium bark, 30 grams of anemarrhena, 30 grams of asparagus, 30 grams of forsythia, 18 grams of perilla, 10 grams of pollen, 15 grams of rutabaga, 15 grams of platycodon, 15 grams of tangerine peel, 15 grams of curcuma, 15 grams of fructus aurantii, 15 grams of arctium, 20 grams of inula flower, 20 grams of angelica dahurica, 20 grams of aristolochia, 20 grams of peucedanum, 20 grams of siler, 20 grams of green peel, 20 grams of aralia, 20 grams of fangji, 20 grams of belamcanda, 20 grams of baiqian. 0 grams, 20 grams of coltsfoot flower, 20 grams of gallnut, 20 grams of Yuanshen, 20 grams of raw rehmannia, 30 grams of licorice, 20 grams of moutan bark, 20 grams of akebia, 20 grams of plantain seed, 20 grams of red peony root, 20 grams of Citrus aurantium, 20 grams of whole Trichosanthes, 5 grams of Glauber's salt, 8 grams of Momordica charantia, 20 grams of ginger powder, 30 grams of mulberry branch, 30 grams of loquat leaf, 30 grams of bamboo leaf, 30 grams of cypress leaf, 30 grams of orange leaf, 15 grams of Zanthoxylum bungeanum, 30 grams of Houttuynia cordata, 30 grams of Isatis root, 30 grams of dandelion, 30 grams of Forsythia suspensa, and the ingredients are medical hot melt adhesive.

4. A children's lung-clearing and asthma-relieving health care patch, applied to a children's lung-clearing and asthma-relieving ointment according to any one of claims 1 to 3, characterized in that: include: Ointment layer, flexible cushioning and comfort layer, waterproof and antibacterial composite backing layer, precise controlled release drug penetration layer; The ointment layer is made by evenly applying the ointment on the non-woven fabric; The flexible cushioning comfort layer is made of a mixture of medical-grade gel material and natural plant extracts; The waterproof and antibacterial composite backing layer is composited with an outer waterproof polyurethane film and an inner antibacterial nano-silver coating; The precise controlled-release drug permeation layer is made of a polymer material with a drug sustained-release function and microcapsules encapsulating the drug.

5. A children's lung-clearing and asthma-relieving health-care patch according to claim 4, characterized in that: The thickness of the ointment in the ointment layer is 0.3-0.5MM, and the thickness of the non-woven fabric is 0.1-0.2MM. A pretreatment step is performed before applying, and the pretreatment step includes degreasing and disinfecting the non-woven fabric.

6. A children's lung-clearing and asthma-relieving health-care patch according to claim 4, characterized in that: The medical-grade gel material comprises polyacrylic acid and polyvinyl alcohol, the ratio of the polyacrylic acid to the polyvinyl alcohol is 3:2, the thickness is 0.5-0.8 mm, and the natural extract comprises menthol and borneol.

7. A children's lung-clearing and asthma-relieving health-care patch according to claim 4, characterized in that: The thickness of the waterproof polyurethane film is 0.05-0.1 mm, the particle size of the nano silver is 20-50 nanometers, and the thickness of the coating is 0.01-0.03 mm.

8. A children's lung-clearing and asthma-relieving health-care patch according to claim 4, characterized in that: The polymer sustained-release material includes hypromellose, the thickness of which is 0.2-0.4 mm, the wall material of the microcapsule includes gelatin and gum arabic, the mass ratio of which is 2:1, and the particle size of the microcapsule is 10-50 microns.