Traditional Chinese medicine composition for treating hyperthyroidism and preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating hyperthyroidism and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 20g of bupleurum chinense, 20 to 40g of radix paeoniae alba, 10 to 20g of selfheal, 10 to 20g of oyster, 5 to 15g of rhizoma bolbostemmae, 5 to 15g of radix curcumae, 10 to 20g of radix scutellariae, 5 to 15g of radix asparagi, 5 to 15g of radix glehniae, 15 to 25g of radix astragali seu hedysari, 5 to 15g of rhizoma atractylodis macrocephalae, 10 to 20g of poria cocos, 10 to 20g of polygala tenuifolia, 10 to 18g of dandelion and 10 to 20g of liquorice root. The traditional Chinese medicine composition has a good treatment effect on hyperthyroidism, has the advantages of quick response and small side effect, can fundamentally control the pathogenesis of hyperthyroidism, and has low recurrence rate after treatment.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating hyperthyroidism, and a preparation method and application thereof. Background Art

[0002] Hyperthyroidism (Hyperthyroidism) is an endocrine disorder characterized by excessive secretion of thyroid hormone. Typical clinical manifestations include exophthalmos, palpitations, excessive sweating, weight loss, and tremors. Some patients are asymptomatic. Possible symptoms include: anxiety, irritability, or sleep disturbances; fatigue, especially in the arms and legs, which can make lifting heavy objects or climbing stairs difficult; tremors; excessive sweating and intolerance of hot weather; a rapid or irregular heartbeat; fatigue; weight loss despite a normal diet; and frequent bowel movements. Hyperthyroidism can also cause a swelling of the neck, called a "goiter." If the hyperthyroidism is caused by Graves' disease, proptosis may also occur. If left untreated, hyperthyroidism can lead to atrial fibrillation (an abnormal heart rhythm), chest pain, and occasionally heart failure. It can also cause osteoporosis, a disease that weakens the bones. Hyperthyroidism can disrupt the menstrual cycle and make it difficult to conceive. It can also cause breast growth in men and sexual problems, which resolve with treatment.

[0003] Western medicine generally considers hyperthyroidism to be an autoimmune disease, classified as an organ-specific autoimmune disease, closely linked to genetic, infectious, and environmental factors. Traditional Chinese Medicine classifies hyperthyroidism as a "goiter," with its core pathogenesis being emotional damage, qi stagnation, and phlegm and blood stasis in the anterior neck. Liver depression and qi stagnation, combined with yin deficiency and hyperactivity of fire, are key pathological links. The interplay of phlegm and blood stasis further contributes to goiter and the formation of nodules.

[0004] There are three main treatments for hyperthyroidism: antithyroid drugs, radioactive iodine therapy, and surgical treatment. However, these three methods are not aimed at the cause but at the symptoms, and cannot achieve a radical cure. There are also problems such as recurrence after discontinuation of the medication and serious adverse reactions. Summary of the Invention

[0005] In view of the above-mentioned deficiencies in the prior art, the present invention provides a traditional Chinese medicine composition for treating hyperthyroidism, a preparation method thereof, and an application thereof. The traditional Chinese medicine composition has a good therapeutic effect on hyperthyroidism, has the advantages of rapid onset of action and few side effects, can fundamentally control the cause of hyperthyroidism, and has a low recurrence rate after treatment.

[0006] To achieve the above-mentioned purpose, the technical solution adopted by the present invention to solve the technical problem is:

[0007] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 10-20g of Bupleurum chinense, 20-40g of White Peony Root, 10-20g of Prunella Vulgaris, 10-20g of Oyster, 5-15g of Fritillaria thunbergii, 5-15g of Curcuma aromatica, 10-20g of Scutellaria baicalensis, 5-15g of Asparagus cochinchinensis, 5-15g of Adenophora australis, 15-25g of Astragalus membranaceus, 5-15g of Atractylodes macrocephala, 10-20g of Poria, 10-20g of Polygala tenuifolia, 10-18g of Taraxacum mongolicum, and 10-20g of Licorice root.

[0008] Further, the invention includes the following components in parts by weight: 13-17g of Bupleurum chinense, 25-35g of White Peony Root, 13-17g of Prunella Vulgaris, 13-17g of Oyster, 8-12g of Fritillaria thunbergii, 8-12g of Curcuma zedoaria, 13-17g of Scutellaria baicalensis, 8-12g of Asparagus cochinchinensis, 8-12g of Adenophora australis, 18-22g of Astragalus membranaceus, 8-12g of Atractylodes macrocephala, 13-17g of Poria, 13-17g of Polygala tenuifolia, 10-14g of Taraxacum mongolicum and 13-17g of Licorice.

[0009] Furthermore, the invention includes the following components in parts by weight: 15g of Bupleurum chinense, 30g of White Peony Root, 15g of Prunella Vulgaris, 15g of Oyster, 10g of Fritillaria thunbergii, 10g of Curcuma aromatica, 15g of Scutellaria baicalensis, 10g of Asparagus cochinchinensis, 10g of Adenophora australis, 20g of Astragalus membranaceus, 10g of Atractylodes macrocephala, 15g of Poria, 15g of Polygala tenuifolia, 12g of Taraxacum mongolicum and 15g of Licorice.

[0010] Further, the invention comprises the following components in parts by weight: 13g of Bupleurum chinense, 35g of White Peony Root, 13g of Prunella Vulgaris, 17g of Oyster, 8g of Fritillaria thunbergii, 12g of Curcuma zedoaria, 13g of Scutellaria baicalensis, 12g of Asparagus cochinchinensis, 8g of Adenophora chinensis, 18g of Astragalus membranaceus, 12g of Atractylodes macrocephala, 13g of Poria cocos, 17g of Polygala tenuifolia, 10g of Taraxacum mongolicum and 13g of Licorice.

[0011] Further, the invention comprises the following components in parts by weight: 17g of Bupleurum chinense, 25g of White Peony Root, 17g of Prunella Vulgaris, 13g of Oyster, 12g of Fritillaria thunbergii, 8g of Curcuma aromatica, 17g of Scutellaria baicalensis, 8g of Asparagus cochinchinensis, 12g of Adenophora scutellariae, 22g of Astragalus membranaceus, 8g of Atractylodes macrocephalae, 17g of Poria, 13g of Polygala tenuifolia, 14g of Taraxacum mongolicum and 17g of Licorice.

[0012] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism includes the following steps: crushing the raw materials and then mixing them; or preparing the composition by mixing or extracting the raw materials separately to obtain an extract; or preparing the composition by further refining and purifying the extract to obtain an effective ingredient; or preparing the composition by adding pharmaceutically acceptable excipients to the extract / active ingredient.

[0013] Furthermore, the prepared dosage form is one of pills, granules, capsules, powders, mixtures, tablets, granules or oral liquids.

[0014] Furthermore, the specific preparation method is as follows: the above fifteen ingredients are decocted with water, the decoction is filtered, concentrated into a clear paste, and granulated with pharmaceutically acceptable excipients to obtain the product.

[0015] Furthermore, the decoction is performed twice, the amount of water added for the first time is 11-13 times the weight of the medicinal material, the decoction time is 1-2 hours, and the amount of water added for the second time is 9-11 times the weight of the medicinal material, the decoction time is 1-2 hours; the relative density of the obtained clear paste is 1.15-1.25.

[0016] Application of the above-mentioned Chinese medicine composition in preparing medicine for treating hyperthyroidism.

[0017] The beneficial effects produced by the present invention are:

[0018] In the present invention, Bupleurum root soothes the liver and relieves depression, elevates Yang Qi, is good at treating chest and flank pain, and can regulate the poor flow of Qi caused by hyperthyroidism, and is used as the main ingredient.

[0019] White peony root nourishes blood and regulates menstruation, astringes yin and stops sweating, softens the liver and relieves pain, and suppresses liver yang. It is sour in taste and mainly enters the liver meridian, and is partial to benefiting the liver's yin and blood. At the same time, it is sour and astringes liver yin, and is partial to softening the liver. It is good at treating blood deficiency, liver depression, and rib pain. It can improve the heart deficiency and impatience caused by hyperthyroidism, and can prevent the excessive drainage of bupleurum from damaging liver yin. Prunella vulgaris tastes bitter and cold in nature, and enters the liver and gallbladder meridians. It has the effects of clearing the liver and purging fire, improving eyesight, dispersing nodules and reducing swelling. It can improve the liver depression and fire, phlegm and blood stasis caused by hyperthyroidism, and can also help the main medicine to clear the liver and disperse nodules, and relieve local thyroid enlargement. Oyster is heavy in texture and enters the liver meridian, which can calm the mind, calm the liver and suppress yang, and astringe and consolidate. Oyster is salty in taste. It can also soften and disperse lumps, enhance the ability to dissipate thyroid nodules and suppress hyperactive Yang Qi; Fritillaria thunbergii clears away heat, resolves phlegm and relieves cough, detoxifies, disperses lumps and eliminates carbuncles, and can improve the ability to dissipate local thyroid nodules; Curcuma zedoaria is pungent and cold in nature, and enters the liver, gallbladder, heart, and lung meridians. It can promote blood circulation and relieve pain, promote qi and relieve depression, clear the heart and cool blood, promote bile and reduce jaundice, and can resolve the symptoms of poor blood circulation caused by qi stagnation, and work together with Bupleurum and White Peony to improve the effect of regulating qi and blood; Scutellaria baicalensis is bitter and cold in nature, and enters the lung, gallbladder, spleen, large intestine, and small intestine meridians. It clears away heat and dampness, purges fire and detoxifies, stops bleeding, and calms the fetus. It can clear and purge stagnant fire in the liver meridian and assist Bupleurum in clearing the liver; all of the above are ministerial drugs.

[0020] Invigorating the spleen and replenishing the spleen, clearing away dampness and moistening the lungs, promoting blood circulation, and clearing away dampness, soothing the kidneys and replenishing the spleen.

[0021] Licorice nourishes the spleen and replenishes qi, and can also clear away heat and detoxify, eliminate phlegm and relieve cough, relieve pain, and harmonize various medicines; it is used as a messenger.

[0022] The above-mentioned medicinal materials complement and interact with each other, and achieve the treatment of hyperthyroidism through the effects of soothing the liver and regulating qi, clearing away heat and dispersing nodules, invigorating qi and nourishing yin, and calming the mind and harmonizing the middle, thereby fundamentally achieving the purpose of treatment. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention. That is, the embodiments described are only part of the embodiments of the present invention, rather than all embodiments.

[0024] Therefore, the detailed description of the embodiments of the present invention provided below is not intended to limit the scope of the invention as claimed, but is merely intended to represent selected embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative work are within the scope of protection of the present invention.

[0025] It should be noted that relational terms such as "first" and "second" are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or apparatus comprising the element.

[0026] The features and performance of the present invention are further described in detail below with reference to the embodiments.

[0027] Example 1

[0028] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 10g of northern bupleurum, 40g of white peony root, 10g of selfheal, 20g of oyster, 5g of fritillaria, 15g of turmeric, 10g of scutellaria, 15g of asparagus, 5g of northern adenophora, 15g of astragalus, 15g of white atractylodes, 10g of poria, 20g of polygala, 10g of dandelion and 10g of liquorice.

[0029] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism comprises the following steps: decocting the above 15 ingredients with water twice, the first time adding water in an amount of 12 times the weight of the medicinal materials and the decocting time being 1.5 hours, and the second time adding water in an amount of 10 times the weight of the medicinal materials and the decocting time being 1 hour, combining the decoctions, filtering, concentrating into a clear paste with a relative density of 1.2, and granulating with dextrin to obtain the product.

[0030] Example 2

[0031] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 20g of Bupleurum chinense, 20g of White Peony Root, 20g of Prunella Vulgaris, 10g of Oyster, 15g of Fritillaria thunbergii, 5g of Curcuma aromatica, 20g of Scutellaria baicalensis, 5g of Asparagus cochinchinensis, 15g of Adenophora australis, 25g of Astragalus membranaceus, 5g of Atractylodes macrocephala, 20g of Poria, 10g of Polygala tenuifolia, 18g of Taraxacum mongolicum, and 20g of Licorice.

[0032] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism comprises the following steps: decocting the above 15 ingredients with water twice, the first time adding water in an amount of 12 times the weight of the medicinal materials and the decocting time being 1.5 hours, and the second time adding water in an amount of 10 times the weight of the medicinal materials and the decocting time being 1 hour, combining the decoctions, filtering, concentrating into a clear paste with a relative density of 1.2, and granulating with dextrin to obtain the product.

[0033] Example 3

[0034] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 15g of Bupleurum chinense, 30g of White Peony Root, 15g of Prunella Vulgaris, 15g of Oyster, 10g of Fritillaria thunbergii, 10g of Curcuma aromatica, 15g of Scutellaria baicalensis, 10g of Asparagus cochinchinensis, 10g of Adenophora australis, 20g of Astragalus membranaceus, 10g of Atractylodes macrocephala, 15g of Poria, 15g of Polygala tenuifolia, 12g of Taraxacum mongolicum, and 15g of Licorice.

[0035] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism comprises the following steps: decocting the above 15 ingredients with water twice, the first time adding water in an amount of 12 times the weight of the medicinal materials and the decocting time being 1.5 hours, and the second time adding water in an amount of 10 times the weight of the medicinal materials and the decocting time being 1 hour, combining the decoctions, filtering, concentrating into a clear paste with a relative density of 1.2, and granulating with dextrin to obtain the product.

[0036] Example 4

[0037] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 13g of Bupleurum chinense, 35g of White Peony Root, 13g of Prunella Vulgaris, 17g of Oyster, 8g of Fritillaria thunbergii, 12g of Curcuma aromatica, 13g of Scutellaria baicalensis, 12g of Asparagus cochinchinensis, 8g of Adenophora australis, 18g of Astragalus membranaceus, 12g of Atractylodes macrocephala, 13g of Poria cocos, 17g of Polygala tenuifolia, 10g of Taraxacum mongolicum, and 13g of Licorice root.

[0038] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism comprises the following steps: decocting the above 15 ingredients with water twice, the first time adding water in an amount of 12 times the weight of the medicinal materials and the decocting time being 1.5 hours, and the second time adding water in an amount of 10 times the weight of the medicinal materials and the decocting time being 1 hour, combining the decoctions, filtering, concentrating into a clear paste with a relative density of 1.2, and granulating with dextrin to obtain the product.

[0039] Example 5

[0040] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 17g of Bupleurum chinense, 25g of White Peony Root, 17g of Prunella Vulgaris, 13g of Oyster, 12g of Fritillaria thunbergii, 8g of Curcuma aromatica, 17g of Scutellaria baicalensis, 8g of Asparagus cochinchinensis, 12g of Adenophora australis, 22g of Astragalus membranaceus, 8g of Atractylodes macrocephala, 17g of Poria, 13g of Polygala tenuifolia, 14g of Taraxacum mongolicum, and 17g of Licorice.

[0041] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism comprises the following steps: decocting the above 15 ingredients with water twice, the first time adding water in an amount of 12 times the weight of the medicinal materials and the decocting time being 1.5 hours, and the second time adding water in an amount of 10 times the weight of the medicinal materials and the decocting time being 1 hour, combining the decoctions, filtering, concentrating into a clear paste with a relative density of 1.2, and granulating with dextrin to obtain the product.

[0042] Comparative Example 1

[0043] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 15g of northern bupleurum, 30g of white peony root, 15g of selfheal, 15g of oyster, 10g of thunbergia bulb, 10g of curcuma, 15g of scutellaria, 10g of asparagus, 10g of ophiopogon, 10g of astragalus, 20g of astragalus, 10g of atractylodes, 15g of poria, 15g of forsythia, 12g of dandelion and 15g of liquorice.

[0044] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism comprises the following steps: decocting the above 15 ingredients with water twice, the first time adding water in an amount of 12 times the weight of the medicinal materials and the decocting time being 1.5 hours, and the second time adding water in an amount of 10 times the weight of the medicinal materials and the decocting time being 1 hour, combining the decoctions, filtering, concentrating into a clear paste with a relative density of 1.2, and granulating with dextrin to obtain the product.

[0045] Comparative Example 2

[0046] A traditional Chinese medicine composition for treating hyperthyroidism comprises the following components in parts by weight: 15g of northern bupleurum, 30g of white peony root, 15g of selfheal, 15g of oyster, 10g of fritillary bulb, 10g of turmeric, 15g of scutellaria, 10g of asparagus, 10g of northern adenophora, 20g of astragalus, 10g of floating wheat, 15g of spinach seed, 15g of polygala, 12g of honeysuckle and 15g of liquorice.

[0047] The preparation method of the above-mentioned traditional Chinese medicine composition for treating hyperthyroidism comprises the following steps: decocting the above 15 ingredients with water twice, the first time adding water in an amount of 12 times the weight of the medicinal materials and the decocting time being 1.5 hours, and the second time adding water in an amount of 10 times the weight of the medicinal materials and the decocting time being 1 hour, combining the decoctions, filtering, concentrating into a clear paste with a relative density of 1.2, and granulating with dextrin to obtain the product.

[0048] Test example

[0049] 1. General Information

[0050] A total of 90 patients who visited the hospital and were diagnosed with hyperthyroidism were selected, including 43 males and 47 females, with an age range of 25-60 years and an average age of 40.5 years.

[0051] 2. Disease Diagnostic Criteria

[0052] 1. Symptoms and signs of high metabolism, such as heat intolerance, sweating, irritability, insomnia, palpitations, increased appetite, weight loss, etc.;

[0053] 2. Enlarged thyroid gland;

[0054] 3. Decreased serum TSH levels and increased thyroid hormone levels;

[0055] 4. Some patients may experience atrial fibrillation, diarrhea, hypokalemic periodic paralysis, etc.

[0056] 3. Method of administration

[0057] The patients were randomly divided into 3 groups, 30 people in each group, and then the drugs in Example 3 and Comparative Examples 1-2 were taken by each group of patients, three times a day, 10 g each time, each gram equivalent to 1.2 g of the original medicinal material, for 4 consecutive weeks, and the patients' conditions were observed.

[0058] IV. Efficacy Evaluation Criteria

[0059] Cure: Hyperthyroidism symptoms and signs completely disappear, and thyroid function returns to normal, that is, serum TSH, FT3, FT4, TT3, TT4 and other indicators remain stable within the normal range, TRAb is negative (for Graves' disease patients), and there is no recurrence within a certain period of time after drug discontinuation (usually more than 1 year);

[0060] Improvement: Hyperthyroidism symptoms and signs have been alleviated, and thyroid function has improved compared to before, but has not yet fully returned to normal, or medication maintenance treatment is still required to control the condition;

[0061] Uncured: Hyperthyroidism symptoms and signs do not improve or worsen, thyroid function remains abnormal, drug treatment is ineffective, or serious complications occur;

[0062] Effectiveness (%) = (number of cured patients + number of improved patients) / total number of patients * 100%

[0063] 5. Treatment Outcomes

[0064] Group Heal (a person) Improvement (people) Unhealed (person) Effectiveness (%) Example 3 20 8 2 93.3％ Comparative Example 1 7 9 14 53.3％ Comparative Example 2 8 8 14 53.3％

[0065] From the results in the above table, it can be seen that the drug in Example 3 has a good therapeutic effect on hyperthyroidism, with an effective rate of up to 93.3%, while the effective rate of the drugs in Comparative Examples 1 and 2 is 53.3%, which is much lower than that of the drug in Example 5. It is speculated that this may be due to the adjustment of the ingredients in the composition, which leads to the disappearance or weakening of the complementary effect between the medicinal materials in the composition, thereby affecting the therapeutic effect.

Claims

1. A Chinese medicine composition for treating hyperthyroidism, characterized in that: The invention comprises the following components in parts by weight: 10-20g of Bupleurum chinense, 20-40g of White Peony Root, 10-20g of Prunella Vulgaris, 10-20g of Oyster, 5-15g of Fritillaria thunbergii, 5-15g of Curcuma zedoaria, 10-20g of Scutellaria baicalensis, 5-15g of Asparagus cochinchinensis, 5-15g of Adenophora australis, 15-25g of Astragalus membranaceus, 5-15g of Atractylodes macrocephala, 10-20g of Poria, 10-20g of Polygala tenuifolia, 10-18g of Taraxacum mongolicum and 10-20g of Licorice.

2. The Chinese medicine composition for treating hyperthyroidism according to claim 1, wherein The invention comprises the following components in parts by weight: 13-17g of Bupleurum chinense, 25-35g of White Peony Root, 13-17g of Prunella Vulgaris, 13-17g of Oyster, 8-12g of Fritillaria thunbergii, 8-12g of Curcuma zedoaria, 13-17g of Scutellaria baicalensis, 8-12g of Asparagus cochinchinensis, 8-12g of Adenophora australis, 18-22g of Astragalus membranaceus, 8-12g of Atractylodes macrocephala, 13-17g of Poria, 13-17g of Polygala tenuifolia, 10-14g of Taraxacum mongolicum and 13-17g of Licorice.

3. The Chinese medicine composition for treating hyperthyroidism according to claim 1 or 2, wherein: The invention comprises the following components in parts by weight: 15g of Bupleurum chinense, 30g of White Peony Root, 15g of Prunella Vulgaris, 15g of Oyster, 10g of Fritillaria thunbergii, 10g of Curcuma aromatica, 15g of Scutellaria baicalensis, 10g of Asparagus cochinchinensis, 10g of Adenophora australis, 20g of Astragalus membranaceus, 10g of Atractylodes macrocephala, 15g of Poria, 15g of Polygala tenuifolia, 12g of Taraxacum mongolicum and 15g of Licorice.

4. The Chinese medicine composition for treating hyperthyroidism according to claim 1 or 2, wherein: The invention comprises the following components in parts by weight: 13g of Bupleurum chinense, 35g of White Peony Root, 13g of Prunella Vulgaris, 17g of Oyster, 8g of Fritillaria thunbergii, 12g of Curcuma zedoaria, 13g of Scutellaria baicalensis, 12g of Asparagus cochinchinensis, 8g of Adenophora chinensis, 18g of Astragalus membranaceus, 12g of Atractylodes macrocephala, 13g of Poria cocos, 17g of Polygala tenuifolia, 10g of Taraxacum mongolicum and 13g of Licorice.

5. The Chinese medicine composition for treating hyperthyroidism according to claim 1 or 2, wherein: The invention comprises the following components in parts by weight: 17g of Bupleurum chinense, 25g of White Peony Root, 17g of Prunella Vulgaris, 13g of Oyster, 12g of Fritillaria thunbergii, 8g of Curcuma aromatica, 17g of Scutellaria baicalensis, 8g of Asparagus cochinchinensis, 12g of Adenophora scutellariae, 22g of Astragalus membranaceus, 8g of Atractylodes macrocephalae, 17g of Poria, 13g of Polygala tenuifolia, 14g of Taraxacum mongolicum and 17g of Licorice.

6. The method for preparing the traditional Chinese medicine composition for treating hyperthyroidism according to any one of claims 1 to 5, characterized in that: The following steps are involved: It is made by crushing and mixing the raw materials; or by extracting the raw materials by mixing or extracting them separately; or by further refining and purifying the extract to obtain the active ingredient; or by adding pharmaceutically acceptable excipients to the extract / active ingredient.

7. The method for preparing the Chinese medicine composition for treating hyperthyroidism according to claim 6, wherein: The prepared dosage form is one of pills, granules, capsules, powders, mixtures, tablets, granules or oral liquids.

8. The method for preparing the Chinese medicine composition for treating hyperthyroidism according to claim 7, wherein: The specific preparation method is as follows: add water to the above fifteen ingredients and boil them, filter the decoction, concentrate it into a clear paste, and granulate it with pharmaceutically acceptable excipients to obtain the product.

9. The method for preparing the Chinese medicine composition for treating hyperthyroidism according to claim 8, wherein: The decoction is performed twice, the amount of water added for the first time is 11-13 times the weight of the medicinal materials, and the decoction time is 1-2 hours, and the amount of water added for the second time is 9-11 times the weight of the medicinal materials, and the decoction time is 1-2 hours; the relative density of the obtained clear paste is 1.15-1.

25.

10. Use of the traditional Chinese medicine composition according to claims 1-5 in the preparation of a medicament for treating hyperthyroidism.