Ternary weeding composition containing pyroxasulfone

Abstract

The invention discloses a ternary weeding composition containing pyroxasulfone, the ternary weeding composition contains effective weeding amounts of pyroxasulfone, diflufenican and trifluralin, the mixture of the pyroxasulfone, diflufenican and trifluralin has a remarkable weeding synergistic effect and lasting time, and monocotyledonous weeds and dicotyledonous weeds can be effectively prevented and removed; according to the present invention, the weeding composition can be applied to weeds such as aegilops tauschii, Italian ryegrass, wild oats, bromegrass, alopecurus aequalis, beckmannia syzigachne, veronica didyma, cleavers, descurainia sophia, shepherd's purse, henbit, lithospermum arvense, chickweed and the like, such that the use amount and the use frequency of the chemical pesticide can be substantially reduced, the safety is improved, and the resistance of the weeds is not easily generated.

Description

Technical Field

[0001] The present application belongs to the technical field of herbicides, and specifically relates to a ternary herbicide composition containing sulfonepyraclostrobin. Background Art

[0002] Chemical herbicides, as important agents for agricultural weed control, are most susceptible to the development of weed resistance. Rationally compounding or blending different herbicides is a common approach in the field. However, current herbicide compounding or blending often results in additive effects. Only synergistic compounding or blending can broaden the weed spectrum, enhance control effectiveness, and slow the onset and development of weed resistance and drug resistance. Therefore, the development of herbicide compositions with high safety, a broad weed control spectrum, synergistic effects, and the ability to address the problem of resistant weeds is highly desirable.

[0003] Pyroxasulfone is a highly effective isoxazole herbicide. Its chemical name is 3-[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-ylmethylsulfonyl]-4,5-dihydro-5,5-dimethyl-1,2-isoxazole, and its molecular formula is C 12 H 14 F5N3O4S, molecular weight is 391.32, CAS registration number is 447399-55-5, and its structural formula is as follows:

[0004]

[0005] It is primarily used for pre-emergence sealing, primarily to kill grass weeds, while also having a certain inhibitory effect on broadleaf weeds. It is widely applicable to crops including wheat, corn, peanuts, rice, soybeans, and cotton, and is safe for both the environment and crops.

[0006] In addition, sulfonepyraclostrobin has excellent compatibility and can be flexibly mixed with a variety of pesticides. Although sulfonepyraclostrobin compound pesticides are currently registered in various countries, there is no ternary mixture of sulfonepyraclostrobin + diflufenac + fluazifop. It is very necessary to develop new sulfonepyraclostrobin-containing mixed pesticides. Summary of the Invention

[0007] In view of this, the primary purpose of the present application is to provide a ternary herbicide composition containing sulfonepyraclostrobin, which mixes herbicidally effective amounts of sulfonepyraclostrobin, diflufenac, and trifluralin. The three have significant synergistic herbicidal effects and long-lasting effects, can greatly reduce the dosage and frequency of use of chemical pesticides, improve safety, and make it less likely for weeds to develop resistance.

[0008] In order to achieve the above objectives, this application adopts the following technical solutions:

[0009] One aspect of the present application discloses a ternary herbicidal composition containing sulfonepyraclostrobin, which contains herbicidally effective amounts of sulfonepyraclostrobin, diflufenac and trifluralin.

[0010] Another aspect of the present application discloses a mixed herbicide containing the ternary herbicidal composition.

[0011] Another aspect of the present application discloses the use of the herbicidal composition or the mixed herbicide in controlling crop weeds.

[0012] Another aspect of the present application discloses a method for controlling the growth of crop weeds, comprising applying an effective amount of the herbicidal composition or the mixed herbicide to weed seeds or weed growth areas.

[0013] Beneficial effects of this application:

[0014] This application combines sulfamethoxam, diflufenacil and fluralin for weed control, which has obvious synergistic effect and long-lasting effect; and the closure time is as long as 60 days, which truly achieves a worry-free one-time use for a whole season.

[0015] The herbicidal composition of the present application expands the weed control spectrum and has a good blocking effect on aesculus fructus, multiflorus ryegrass, wild oats, brome, alopecuroides, sedge, veronica, cleaver, sophora flavescens, shepherd's purse, sedge grass, sedge family, and chickweed in wheat fields.

[0016] The use of the herbicidal composition of the present application can reduce the amount and frequency of pesticide application, thereby reducing the risk of pesticide damage after crop emergence and alleviating environmental pollution.

[0017] The herbicidal composition of the present application is safe to humans and animals, environmentally friendly, and weeds are not likely to develop resistance. DETAILED DESCRIPTION

[0018] The following will clearly and completely describe the embodiments of the present application. The technical solutions in the embodiments described below are exemplary and are only possible technical implementations of the present application, not all possible implementations. Those skilled in the art can fully combine the embodiments of the present application to obtain other embodiments without creative work, and these embodiments are also within the scope of protection of the present application.

[0019] The first aspect of the present application discloses a ternary herbicidal composition containing sulfonepyraclostrobin, which contains herbicidally effective amounts of sulfonepyraclostrobin, diflufenac and trifluralin.

[0020] After screening and experimenting with a large number of drugs in the early stage, the inventors of the present application found that a mixture of sulfamethoxazole, diflufenacil and trifluralin has a significant synergistic herbicidal effect with a long-lasting effect.

[0021] According to the introduction of the background technology, it is known that pyroxasulfone is a highly effective isoxazole herbicide. The present application provides a ternary herbicide composition based on pyroxasulfone.

[0022] Diflufenicam is a substituted pyridinylanilide herbicide, chemical name: N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide, molecular formula: C 19 H 11 F5N2O2, relative molecular mass: 394.29, CAS registration number: 83164-33-4, its structural formula is as follows:

[0023]

[0024] Flufenacet is a carotenoid biosynthesis inhibitor. It inhibits the activity of phytoene dehydrogenase in weeds, hindering carotenoid biosynthesis. This prevents weeds from synthesizing pigments, causing them to bleach and eventually die due to a lack of photosynthesis. It has a strong soil persistence, allowing a single application to effectively control weed growth throughout the crop's growth period. A low dosage is required for effective weed control. It effectively controls a variety of annual grasses and broadleaf weeds, such as crabgrass, barnyard grass, foxtail grass, quinoa, amaranth, and polygonum. At normal application doses, it is safe for crops and environmentally friendly, with low soil residues and minimal impact on subsequent crops. It is primarily used in fields of wheat, barley, rapeseed, peanuts, soybeans, orchards, and other crops, as well as in non-arable land, to control annual grasses and broadleaf weeds. It can be applied before sowing or before crop emergence, with soil sealing as a treatment, or after emergence as a stem and foliage treatment.

[0025] Trifluralin is an excellent dryland herbicide. Chemical name: 2,6-dinitro-N,N-dipropyl-4-trifluoromethylaniline. Molecular formula: C 13 H 16 F3N3O4, molecular weight: 335.28, its structural formula is as follows:

[0026]

[0027] It is mainly used for the prevention and control of weeds in crops such as cotton, soybean, peanut, sunflower, cabbage, pepper, bean, orchard, etc. It can also be used in wheat fields and dry rice fields to prevent and control annual grasses and seed-propagated weeds and some broad-leaved weeds, such as barnyard grass, foxtail grass, crabgrass, alopecuroides, cricket grass, kiwi fruit, bluegrass, brome, wild oats, bromegrass, quinoa, amaranth, corn grass, chickweed, kochia, purslane, etc.

[0028] The three aforementioned pesticides, when used individually, have the problem of high dosages and the tendency to develop resistance. After extensive pesticide screening experiments, the applicant discovered that a mixture of the three significantly enhances herbicidal effects, is environmentally friendly, and can significantly reduce the amount and frequency of pesticide use. Furthermore, this mixture offers the advantage of a long-lasting effect, with a closure time of up to 120 days, ensuring a worry-free, one-time application for a whole season.

[0029] In the present application, the content of the three active ingredients in the ternary herbicidal composition is a herbicidally effective amount, and the herbicidally effective amount here refers to the total amount and / or the respective dosage of the active ingredients (A+B+C) in the herbicidal composition, so that when the herbicidal composition is applied to the target area, it has a synergistic effect. The synergistic effect here includes but is not limited to: ① The control effect on target weeds is significantly better than the theoretical sum of each single agent; ② The persistence of inhibiting weed growth is still shown at a half-lethal dose; ③ The weed control spectrum is expanded to cover weed species that cannot be controlled by a single agent; ④ The risk of phytotoxicity of the target crop is reduced while maintaining or improving the weed control efficiency. There is no special limitation on the effective dose described herein, and those skilled in the art can determine it using experimental methods well known in the art, such as the Colby method or Gowing method to determine the corresponding dose.

[0030] In some examples, the mass ratio of sulfonepyraclostrobin, diflufenac, and trifluralin is 1-500:1-200:2-3000. Preferably, the mass ratio of sulfonepyraclostrobin, diflufenac, and trifluralin is 20-200:1-150:30-2000. More preferably, the mass ratio of sulfonepyraclostrobin, diflufenac, and trifluralin is 45-180:33.75-135:270-1080.

[0031] A second aspect of the present application discloses a mixed herbicide comprising the ternary herbicidal composition described above. Because the main active ingredient of the mixed herbicide is the ternary herbicidal composition described above, it exhibits excellent weed control efficacy, broadens the weed control spectrum, reduces drug dosage, and improves weed control effectiveness.

[0032] There is no particular requirement for the proportion of the ternary herbicide composition in the mixed herbicide, and it can be determined experimentally. In some examples, the weight proportion of the ternary herbicide composition is 1 to 95%. Preferably, the weight proportion of the ternary herbicide composition in the mixed herbicide is 10 to 80%.

[0033] It is understandable that the mixed herbicide contains not only the ternary herbicidal composition described above, but also any at least one pesticide-acceptable adjuvant and / or carrier.

[0034] The types of excipients and / or carriers described herein vary depending on the formulation of the mixed herbicide. Those skilled in the art can select appropriate excipients and / or carriers based on the desired formulation. Examples of such excipients and / or carriers include dispersants, wetting agents, disintegrants, emulsifiers, antifreeze agents, defoaming agents, thickeners, polymeric capsule wall materials, and fillers. Specific types are generally selected from conventional sources in the art.

[0035] For the dispersant, for example, it can be one or a combination of two or more of bis(alkyl)naphthalenesulfonate formaldehyde condensate, alkylnaphthalenesulfonate, naphthalenesulfonic acid formaldehyde condensate, arylphenol polyoxyethylene succinate sulfonate, polycarboxylate, lignin sulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, fatty amine polyoxyethylene ether, octylphenol polyoxyethylene ether sulfate, alkylbenzenesulfonic acid calcium salt, naphthalenesulfonic acid formaldehyde condensate sodium salt, alkylphenol polyoxyethylene ether, fatty acid polyoxyethylene ester, and sorbitan fatty acid ester polyoxyethylene ether, but is not limited thereto.

[0036] For the wetting agent, for example, it can be one or a combination of two or more of sodium dodecylbenzene sulfonate, sodium dodecyl sulfate, soapberry powder, tea dregs, silkworm feces, Lakai powder BX, laundry detergent, Nongru 2000# series, sodium lauryl sulfate, wetting penetrant F, wetting agent T, and soapberry powder, but is not limited thereto.

[0037] The disintegrant may be, for example, one or a combination of two or more of ammonium sulfate, aluminum chloride, bentonite, urea, and glucose, but is not limited thereto.

[0038] For emulsifiers, for example, styrene polyoxyethylene ether ammonium sulfate, Nongru 500# (alkylbenzene sulfonate calcium), 600# phosphate (phenylphenol polyoxyethylene ether phosphate), OP series phosphate (nonylphenol polyoxyethylene ether phosphate), alkyl diphenyl ether disulfonic acid magnesium salt, triethanolamine salt, Nongru 400# (benzyl dimethylphenol polyoxyethyl ether), Nongru 600# (phenylphenol polyoxyethyl ether), Nongru 700# (alkylphenol formaldehyde resin polyoxyethyl ether), Nongru 36# (phenylethylphenol formaldehyde resin polyoxyethyl ether), Nongru 1600# (phenylethylphenol polyoxyethyl polypropylene ether), ethylene oxide-propylene oxide block copolymer, OP series (nonylphenol polyoxyethylene ether), By series (castor oil polyoxyethylene ether), Nongru 33# (alkyl aryl polyoxypropylene polyoxyethylene ether), Nongru 34# (alkyl aryl polyoxyethylene polyoxypropylene ether), Tween series (sorbitan fatty acid ester polyoxyethylene ether), Span series (sorbitan monostearate), EO series (polyoxyethylene fatty alcohol ether) or a combination of two or more thereof, but not limited thereto.

[0039] The antifreeze agent may be, for example, one of propylene glycol, glycerol, ethylene glycol, and polyethylene glycol, or a combination of two or more thereof, but is not limited thereto.

[0040] The defoaming agent may be, for example, one or a combination of two or more of silicones, C8-10 fatty alcohols, C10-20 saturated fatty acids (such as capric acid), amides, silicone oils, and silicone compounds, but is not limited thereto.

[0041] The thickener may be, for example, one or a combination of two or more of xanthan gum, methyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, magnesium aluminum silicate, and polyvinyl alcohol, but is not limited thereto.

[0042] For the polymer capsule wall material, for example, it can be one or a combination of two or more of urea, multifunctional acyl halide polyamine, formaldehyde, polyisocyanate, multifunctional acyl halide diol, gum arabic, sucrose, modified starch, sodium alginate, polyvinyl alcohol, gelatin, maltose, deformed lactoprotein, glycerol, calcium chloride, carboxymethyl cellulose, and β-cyclodextrin, but is not limited thereto.

[0043] The filler may be, for example, one or a combination of two or more of diatomaceous earth, bentonite, attapulgite, kaolin, white carbon black, starch, light calcium carbonate, and vegetable oil, but is not limited thereto.

[0044] Furthermore, it is understood that the pesticide formulation of the mixed herbicide can be any formulation in pesticide science, but preferably a formulation that facilitates the exertion of its efficacy or effect. Those skilled in the art have such capabilities. In some examples, the pesticide formulation of the mixed herbicide is one of an aqueous suspension concentrate, suspoemulsion, wettable powder, emulsifiable concentrate, water-dispersible granules, emulsion in water, microemulsion, or microcapsule suspension. The composition and preparation of the specific formulation can be configured by those skilled in the art as needed.

[0045] In some examples, the mixed drug is in the form of an aqueous suspension. In some specific examples, the aqueous suspension comprises the following weight percentages: 1-20% pyraclostrobin, 1-30% diflufenac, 2-40% fluralin, 2-10% dispersant, 2-10% wetting agent, 0.1-1% defoamer, 0.1-2% thickener, 0.1-8% antifreeze, and deionized water added to 100%. The preparation process is as follows: the dispersant, wetting agent, defoamer, thickener, antifreeze, and deionized water in the above formula are mixed uniformly by high-speed shearing; then, pyraclostrobin, diflufenac, and fluralin are added and ball-milled in a ball mill for 2-3 hours to reduce the particle size to less than 5 μm, thereby producing an aqueous suspension.

[0046] In other examples, the dosage form of the mixed agent is a suspoemulsion. In some specific examples, the mass percentage composition of the suspoemulsion is: 1-20% of sulfometrazoline, 1-30% of diflufenac, 2-40% of fluralin, 2-12% of emulsifier, 2-10% of dispersant, 0.1-2% of defoamer, 0.1-2% of thickener, 0.1-8% of antifreeze, 0.05-3% of stabilizer, and deionized water added to 100%; its preparation process is: according to the amount, the dispersant, defoamer, thickener, antifreeze, stabilizer, and deionized water in the above formula are mixed uniformly through high-speed shearing, sulfometrazoline, diflufenac, and fluralin technical are added, and the mixture is ball-milled in a ball mill for 2-3 hours to reduce the particle size of all particles to less than 5 μm to prepare a suspension concentrate, and the emulsifier and various additives are directly emulsified into the suspension concentrate using a high-speed stirrer to prepare a suspoemulsion.

[0047] In other examples, the mixed herbicide is formulated as a wettable powder. In some specific examples, the wettable powder comprises the following weight percentages: 1-20% sulfometrazoline, 1-30% diflufenac, 2-40% trifluralin, 5-10% dispersant, 2-10% wetting agent, and filler to 100%. The preparation process comprises: combining sulfometrazoline, diflufenac, trifluralin, dispersant, wetting agent, and filler according to the required amount, mixing thoroughly in a mixing tank, pulverizing in a jet mill, and then mixing thoroughly to produce the wettable powder.

[0048] In other examples, the mixed herbicide is formulated as a water-dispersible granule. In some specific examples, the weight percentage composition of the water-dispersible granules is: 1-20% sulfometrazoline, 1-30% diflufenac, 2-40% trifluralin, 3-12% dispersant, 1-8% wetting agent, 1-10% disintegrant, and filler to 100%. The preparation process involves air-flow milling sulfometrazoline, diflufenac, trifluralin, dispersant, wetting agent, disintegrant, and filler according to the required amount to obtain the desired particle size, thereby obtaining the granulation material. The material is then quantitatively fed into a fluidized bed granulation dryer for granulation and drying to obtain the water-dispersible granules.

[0049] In other examples, the mixed herbicide is formulated as an emulsion in water. In some specific examples, the emulsion's mass percentage composition is: 1-20% pyraclostrobin, 1-30% diflufenac, 2-40% trifluralin, 0.1-30% solvent, 1-15% emulsifier, 0.1-8% co-emulsifier, 0.1-10% antifreeze, 0.1-2% thickener, 0.01-2% defoamer, and deionized water to 100%. The preparation process involves mixing the above formula according to the dosage, adding the active ingredient, solvent, emulsifier, and co-emulsifier together to dissolve into a uniform oil phase; then mixing water, antifreeze, thickener, and defoamer together to form a uniform aqueous phase. The aqueous phase is then added to the oil phase under high-speed stirring to produce the emulsion in water product described herein.

[0050] In other examples, the formulation of the mixed herbicide is a microemulsion. In some specific examples, the mass percentage composition of the microemulsion is: 1-20% of sulfometrazoline, 1-30% of diflufenac, 2-40% of fluralin, 0.1-30% of solvent, 3-20% of emulsifier, 0.1-12% of co-emulsifier, 0.1-10% of antifreeze, 0.1-2% of thickener, 0.01-2% of defoamer, 0.1-4% of stabilizer, and deionized water is added to 100%. The preparation process is as follows: dissolve sulfometrazoline, diflufenac, and fluralin in a homogenizer filled with solvent and cosolvent according to the amount used; add the emulsifier, stabilizer, antifreeze, and water to the homogenizer filled with the above solution, then vigorously mix and homogenize, and finally obtain a microemulsion with a clear and transparent appearance.

[0051] In other examples, the formulation of the mixed herbicide is a microcapsule suspension. In some specific examples, the mass percentage composition of the microcapsule suspension is: 1-20% pyraclostrobin, 1-30% diflufenac, 2-40% trifluralin, 1-12% polymer wall material, 2-10% surfactant, 1-15% organic solvent, 1-8% emulsifier, 0.1-5% pH adjuster, and deionized water added to 100%. Its preparation process can be: according to the amount used, the polymer wall material is added to the pH adjuster and heated to a certain temperature to obtain a viscous liquid, which is then diluted with water to form a stable prepolymer solution; the active ingredient is dissolved in the organic solvent and then added to the prepolymer solution. Finally, the emulsifier and surfactant are added, and the mixture is dispersed into extremely fine particles by thorough shear stirring. The pH adjuster is then added, and the temperature is increased to catalyze polycondensation to form strong and impermeable microcapsules to produce the microcapsule suspension. Alternatively, an interfacial polymerization method is used to mix the diflufenac, trifluralin, a polymeric capsule wall material, and an organic solvent in the above formulation into a uniform oil phase; the oil phase is added to an aqueous solution containing an emulsifier and a pH adjuster under shear conditions, and the two materials react at the oil-water interface to form a polymeric capsule wall around the droplets containing the chemical substances, thereby producing a microcapsule suspension. Alternatively, a surfactant, a defoamer, a thickener, and an antifreeze agent are uniformly mixed under high-speed shear, and the sulfometrazoline technical is added. The mixture is ball-milled in a ball mill for 2-3 hours to reduce the particle size to less than 5 μm, thereby producing a sulfometrazoline suspension; the stable sulfometrazoline suspension dissolved in water is then added to the aforementioned microcapsule suspension to produce a well-dispersed microcapsule suspension.

[0052] The third aspect of the present application discloses the use of the herbicidal composition or the mixed herbicide as described above in controlling crop weeds.

[0053] In the present application, the crop is preferably wheat; the weeds are preferably resistant weeds in wheat fields, and specific examples include but are not limited to at least one of Aegilops tauschii, Lolium multiflorum, wild oats, Bromus, Alopecurus mume, Alopecurus scabra, Veronica officinalis, Glechoma longituba, Artemisia selengensis, Shepherd's purse, Herba Lycopodii, Aesculus fragrans, and Chickweed.

[0054] A fourth aspect of the present application discloses a method for controlling weed growth in crops, comprising applying an effective amount of the herbicidal composition or the mixed herbicide to weed seeds or an area where weeds grow. The specific application method is not particularly limited, and those skilled in the art can select an appropriate application method based on the dosage form and other factors.

[0055] The following are specific embodiments of the present application. It should be noted that the following specific embodiments are only for illustrative purposes and do not limit the scope of the present application in any way.

[0056] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application pertains. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0057] In addition, unless otherwise specified, methods without specific conditions or steps are conventional methods, and the reagents and materials used are all commercially available.

[0058] Example 1: 20% sulfonepyraclostrobin·pyraclostrobin·trifluralin wettable powder

[0059] 5% of sulfonepyraclostrobin, 5% of diflufenacil, 10% of trifluralin, 6% of polycarboxylate, 5% of sodium lauryl sulfate and attapulgite are added to 100% and mixed, and then the mixture is air flow-pulverized and mixed evenly to prepare 20% sulfonepyraclostrobin·diflufenacil·trifluralin wettable powder.

[0060] Example 2: 40% sulfonepyraclostrobin·pyraclostrobin·trifluralin wettable powder

[0061] 10% of sulfonepyraclostrobin, 15% of diflufenacil, 15% of fluralin, 6% of alkylphenol polyoxyethylene ether, 4% of tea dung and kaolin are added to 100%, and the mixture is subjected to air flow grinding to prepare 40% sulfonepyraclostrobin·diflufenacil·fluralin wettable powder.

[0062] Example 3: 70% sulfonepyraclostrobin·pyraclostrobin·trifluralin wettable powder

[0063] 20% of sulfonepyraclostrobin, 20% of diflufenac, 30% of fluralin, 6% of alkylphenol polyoxyethylene ether, 4% of soapberry powder and kaolin are added to 100%, and the mixture is subjected to air flow grinding to prepare 70% sulfonepyraclostrobin·diflufenac·fluralin wettable powder.

[0064] Example 4: 70% sulfone metabendazole·difluanid·trifluralin water dispersible granules

[0065] 20% of sulfonepyraclostrobin, 30% of diflufenacil, 20% of fluralin, 6% of alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, 5% of sodium lauryl sulfate, 2% of urea and kaolin are added to 100% and mixed to prepare 70% sulfonepyraclostrobin, diflufenacil and fluralin water dispersible granules.

[0066] Example 5: 60% sulfone metabendazole, difluanid, and trifluralin water dispersible granules

[0067] 15% of sulfonepyraclostrobin, 15% of diflufenacil, 30% of fluralin, 4% of sodium dodecylbenzenesulfonate, 6.8% of sodium salt of naphthalenesulfonic acid formaldehyde condensate, 2.2% of ammonium sulfate and bentonite are added to 100% and mixed to prepare 60% sulfonepyraclostrobin, diflufenacil and fluralin water dispersible granules.

[0068] Example 6: 66% sulfone metabendazole·difluanid·trifluralin water dispersible granules

[0069] 10% of sulfonepyraclostrobin, 16% of diflufenacil, 40% of trifluralin, 6% of lakai powder BX, 10% of sorbitan fatty acid ester polyoxyethylene ether, 2% of glucose, and bentonite are added and mixed to prepare 66% sulfonepyraclostrobin·diflufenacil·trifluralin water dispersible granules.

[0070] Example 7: 56% sulfone metabendazole·pyraclostrobin·trifluralin suspension

[0071] 10% of sulfonepyraclostrobin, 16% of diflufenacil, 30% of fluralin, 5% of polycarboxylate, 4% of sodium dodecylbenzenesulfonate, 2% of C10-20 saturated fatty acids, 1.2% of polyvinylpyrrolidone, 0.8% of diethylene glycol and deionized water were added to 100% and mixed to prepare 56% sulfonepyraclostrobin·diflufenacil·fluralin suspension.

[0072] Example 8: 60% sulfone metabendazole·pyraclostrobin·trifluralin suspension

[0073] 10% of sulfonepyraclostrobin, 10% of diflufenacil, 40% of fluralin, 6% of alkylphenol polyoxyethylene ether, 6% of sodium lauryl sulfate, 1% of silicones, 2% of sodium alginate and deionized water are added to 100% and mixed to prepare a 60% sulfonepyraclostrobin·diflufenacil·fluralin suspension.

[0074] Example 9: 65% sulfone metabendazole·pyraclostrobin·trifluralin suspension

[0075] 15% of sulfonepyraclostrobin, 20% of diflufenac, 30% of fluralin, 6% of fatty acid polyoxyethylene ester, 5% of silkworm excrement, 1.2% of C8-10 fatty alcohols, 2% of polyvinyl alcohol, and deionized water are added to 100% and mixed to prepare a 65% sulfonepyraclostrobin·diflufenac·fluralin suspension.

[0076] Example 10: 40% sulfonepyraclostrobin·difluanid·trifluralin suspoemulsion

[0077] 5% of sulfonepyraclostrobin, 15% of diflufenacil, 20% of fluralin, 7% of sodium salt of naphthalenesulfonic acid formaldehyde condensate, 6% of sodium dodecylbenzenesulfonate, 6% of benzyldimethylphenol polyoxyethyl ether, 5% of ethyl acetate, 1% of C8-10 fatty alcohols, 2% of polyvinyl alcohol, 1.8% of polyethylene glycol, and deionized water are added to 100% and mixed to prepare a 40% sulfonepyraclostrobin·diflufenacil·fluralin suspension emulsion.

[0078] Example 11: 32% sulfonepyraclostrobin·difluanid·trifluralin suspoemulsion

[0079] 10% of sulfonepyraclostrobin, 12% of diflufenacil, 10% of fluralin, 7% of fatty acid polyoxyethylene ester, 4% of soapberry powder, 2% of castor oil polyoxyethylene ether, 0.8% of silicone oil, 1.5% of hydroxymethyl cellulose, 2% of polyethylene glycol, and deionized water are added to 100% and mixed to prepare a 32% sulfonepyraclostrobin·diflufenacil·fluralin suspension emulsion.

[0080] Example 12: 18% sulfonepyraclostrobin·difluanid·trifluralin suspoemulsion

[0081] 5% of sulfonepyraclostrobin, 7% of diflufenacil, 6% of fluralin, 6% of dehydrated sorbitan fatty acid ester polyoxyethylene ether, 4% of tea dregs, 5% of styrenephenol polyoxyethylene ether ammonium sulfate, 0.5% of silicones, 1.5% of phenolic resin, 1.2% of ethylene glycol, and deionized water are added to 100% and mixed to prepare an 18% sulfonepyraclostrobin·diflufenacil·fluralin suspoemulsion.

[0082] Example 13: 45% sulfone metabendazole·difluanid·trifluralin microemulsion

[0083] 20% of sulfonepyraclostrobin, 20% of diflufenac, 5% of fluralin, 7% of dehydrated sorbitan fatty acid ester polyoxyethylene ether, 4% of cyclohexanone, 1% of diethylene glycol, 1% of sodium acrylate, 0.9% of silicone oil, 2% of organic acid, and deionized water are added to 100% to prepare a 45% sulfonepyraclostrobin·diflufenac·fluralin microemulsion.

[0084] Example 14: 35% disulfone metabendazole·difluanid·trifluralin microemulsion

[0085] 35% sulfonepyraclostrobin·flumifenazir·fluralin microemulsion was prepared by adding 15% sulfonepyraclostrobin, 10% diflufenacil, 10% fluralin, 7% N-pyrrolidone, 5% xanthan gum, 1.6% phenolic resin, 7% fatty alcohol polyoxyethylene ether, 1.4% C8-10 fatty alcohols, 1.5% ethanolamine, and deionized water to make up 100%.

[0086] Example 15: 40% sulfone metabendazole·difluanid·trifluralin microemulsion

[0087] 10% of sulfonepyraclostrobin, 13% of diflufenacil, 17% of fluralin, 7% of butyl ether, 6% of phenylethylphenol formaldehyde resin polyoxyethyl ether, 1.5% of sodium acrylate, 2% of propylene glycol, 1.4% of silicones, 1% of triethanolamine, and deionized water to make up 100% are mixed to prepare a 40% sulfonepyraclostrobin·diflufenacil·fluralin microemulsion.

[0088] Example 16: 50% sulfonepyraclostrobin·difluanid·trifluralin aqueous emulsion

[0089] 20% of sulfonepyraclostrobin, 10% of diflufenacil, 20% of fluralin, 5% of toluene, 5% of vegetable oil, 6% of phenylethylphenol formaldehyde resin polyoxyethyl ether, 2% of propylene glycol, 0.8% of C8-10 fatty alcohols, and deionized water are added to 100% and mixed to prepare a 50% sulfonepyraclostrobin·diflufenacil·fluralin aqueous emulsion.

[0090] Example 17: 25% sulfone metabendazole·difluanid·trifluralin aqueous emulsion

[0091] 5% of sulfonepyraclostrobin, 10% of diflufenacil, 10% of fluralin, 4% of acetonitrile, 3% of propanol, 8% of castor oil polyoxyethylene ether, 1.6% of propylene glycol, 1.5% of C8-10 fatty alcohols and deionized water are added to 100% and mixed to prepare a 25% sulfonepyraclostrobin·diflufenacil·fluralin aqueous emulsion.

[0092] Example 18: 20% sulfonepyraclostrobin·difluanid·trifluralin aqueous emulsion

[0093] 10% of sulfonepyraclostrobin, 5% of diflufenacil, 5% of fluralin, 4% of acetone, 5% of vegetable oil, 8% of sorbitan monostearate, 1.8% of polyvinyl alcohol, 0.8% of silicones and deionized water are added to 100% and mixed to prepare a 20% sulfonepyraclostrobin·diflufenacil·fluralin aqueous emulsion.

[0094] Example 19: 39% sulfone metabendazole·pyraclostrobin·trifluralin microcapsule suspension

[0095] 15% of sulfonepyraclostrobin, 12% of diflufenacil, 12% of fluralin, 3% of sodium alginate, 2% of maltose, 5% of sodium dodecylbenzenesulfonate, 2.4% of anhydrous sorbitan fatty acid ester polyoxyethylene ether, 6% of cyclohexanone, 5% of alkylphenol formaldehyde resin polyoxyethyl ether, 0.9% of citric acid, 0.6% of sodium hydroxide and deionized water are added to 100% by weight to prepare a 39% sulfonepyraclostrobin·diflufenacil·fluralin microgel suspension.

[0096] Example 20: 40% sulfone metabendazole·pyraclostrobin·trifluralin microcapsule suspension

[0097] 10% of sulfonepyraclostrobin, 15% of diflufenacil, 15% of fluralin, 3% of sodium alginate, 2% of maltose, 5% of sodium dodecylbenzenesulfonate, 2.4% of anhydrous sorbitan fatty acid ester polyoxyethylene ether, 6% of cyclohexanone, 5% of alkylphenol formaldehyde resin polyoxyethyl ether, 0.9% of citric acid, 0.6% of sodium hydroxide and deionized water are added to 100% by weight to prepare 40% sulfonepyraclostrobin, diflufenacil and fluralin microcapsule suspension.

[0098] Example 21: 36% sulfone metabendazole·pyraclostrobin·trifluralin microcapsule suspension

[0099] 10% of sulfonepyraclostrobin, 13% of diflufenacil, 13% of fluralin, 3% of sodium alginate, 2% of maltose, 5% of sodium dodecylbenzenesulfonate, 2.4% of anhydrous sorbitan fatty acid ester polyoxyethylene ether, 6% of cyclohexanone, 5% of alkylphenol formaldehyde resin polyoxyethyl ether, 0.9% of citric acid, 0.6% of sodium hydroxide and deionized water are added to 100% by weight to prepare a 36% sulfonepyraclostrobin·diflufenacil·fluralin microcapsule suspension.

[0100] Bioefficacy testing

[0101] Soil sealing treatment

[0102] 1. Test conditions

[0103] (1) Test targets: Aegilops tauschii Coss. and Veronica polita Fries were collected from Mengcheng, Anhui Province.

[0104] (2) Culture conditions: The above weeds were cultured using the potting method. 180×140mm plastic nutrient pots were placed in stainless steel trays, filled with air-dried and sieved surface soil (4 / 5 of the soil) collected from farmland. The soil moisture was initially controlled at 20%. Weed seeds with plump and uniform grains were selected and soaked in 25℃ warm water for 6 hours. Germination was accelerated in a 28℃ biochemical incubator (dark). The weed seeds that had just turned white were evenly placed on the soil surface and then covered with 0.7cm of soil. After the treatment with the chemical, they were cultured in a controlled sunlight greenhouse. A certain amount of water was regularly added to the stainless steel tray to keep the soil moist.

[0105] The experiment was conducted in a controlled sunlight greenhouse at a temperature of 18-30°C, natural light, and a relative humidity of 57%-72%. The soil type was loam, with an organic matter content of 1.64%, a pH of 7.1, 84.2 mg / kg of alkaline-hydrolyzable nitrogen, 38.6 mg / kg of available phosphorus, and 82.0 mg / kg of available potassium.

[0106] 2. Experimental Design

[0107] (1) Reagents: 98% pyraclostrobin, 98% diflufenac, and 97% trifluralin technicals were provided by the R&D Department of Anhui Fengle Agrochemical Co., Ltd. The technicals were diluted with 0.1% aqueous solution of emulsifier T-80 using acetone as the solvent. Dilute immediately before use.

[0108] (2) Experimental treatment

[0109] a. Dosage Setting: When determining the dosage ratio or content of each group, the characteristics and toxicity of the three agents should be considered, as well as the primary purpose of the formulation. Based on preliminary pilot studies, this study set dosages for single and combined use. Water containing no agents but the same solvent and emulsifier served as a blank control.

[0110] b. Experimental replication: Each treatment was replicated 4 times, with 3 pots of each weed species per treatment, 20 weed seeds per pot, and a total of 60 plants per treatment.

[0111] (3) Treatment method

[0112] a. Treatment time and frequency: Apply the pesticide once, 24 hours after sowing.

[0113] b. Application method: Place the cultivated test materials evenly in an area of ​​0.5m 2 On a platform, use a walking sprayer to spray the soil surface at a rate of 450 kg / hectare. Use a spray pressure of 0.3 MPa. Once all the liquid has been sprayed, close the air valve. After 30 seconds, open the spray tower door and remove the nutrient pots. Then, open the air valve and spray 50 mL of clean water to clean the spray pipe.

[0114] (4) Test method

[0115] The potting method was used. Weed cultivation was carried out in accordance with the "Guidelines for Indoor Pesticide Bioassays for Herbicides." The soil treatment method was used.

[0116] (5) Survey and data statistics

[0117] a. Survey Method: Use the absolute number survey method. Use a razor blade to cut off surviving weed seedlings along the soil surface and weigh the fresh weight of the weeds using an analytical balance. Dead weeds are counted as zero.

[0118] b. Investigation time and frequency: Investigation will be conducted 15 days after treatment, for a total of 1 investigation.

[0119] c. Data analysis: Colby method was used to evaluate the combined effects of any two or three compounds on weeds.

[0120] On the 15th day, the aboveground green tissues of each treatment were cut and weighed using an electronic balance. The actual survival rate and theoretical survival rate were calculated according to the following formula.

[0121] Actual survival rate: E (%) = (fresh weight of weeds in the treatment area / fresh weight of weeds in the control area) × 100;

[0122] Theoretical weed survival rate: E0 (%) = X × Y / 100 (binary mixture);

[0123] Where X represents the weed survival rate of A when the dosage is P, Y represents the weed survival rate of B when the dosage is Q, E0 represents the theoretical weed survival rate of A+B when the dosage is (P+Q), and E represents the actual weed survival rate of each treatment.

[0124] Theoretical weed survival rate: E0 (%) = X × Y × Z × ... × N / 100 ( n-1) (Three or more mixed)

[0125] Where X, Y, Z, and N represent the actual survival rates of n single agents, and n is the number of compound herbicide varieties.

[0126] When E0-E>10%, it indicates a synergistic effect; when E0-E<-10%, it indicates an antagonistic effect; when E0-E is between ±10%, it indicates an additive effect.

[0127] The experimental results are shown in Tables 1 and 2.

[0128] In Table 1, A is sulfamethoxazole, B is diflufenacil, C is trifluralin, and the target is Aegilops tauschii.

[0129] Table 1 Bio-efficacy test results (Aegilops tauschii)

[0130]

[0131]

[0132] In Table 1, E1 is E(A+B) (%); E2 is E(A+C) (%); E3 is E(B+C) (%); and E4 is E(A+B+C) (%).

[0133] E5 is E0(A+B+C)(%); E6 is E0((A+B)+C)(%); E7 is E0((A+C)+B)(%); E8 is E0(A+(B+C))(%).

[0134] E9 is E0(A+B+C)-E(A+B+C)(%); E10 is E0((A+B)+C)-E(A+B+C)(%); E11 is E0((A+C)+B)-E(A+B+C)(%); E12 is E0(A+(B+C))-E(A+B+C)(%)

[0135] In Table 2, A is diflufenacil, B is fluazifop, C is trifluralin, and the target is Veronica officinalis.

[0136] Table 2 Bio-efficacy test results (Veronica officinalis)

[0137]

[0138] In Table 2, E1 is E(A+B) (%); E2 is E(A+C) (%); E3 is E(B+C) (%); and E4 is E(A+B+C) (%).

[0139] E5 is E0(A+B+C)(%); E6 is E0((A+B)+C)(%); E7 is E0((A+C)+B)(%); E8 is E0(A+(B+C))(%).

[0140] E9 is E0(A+B+C)-E(A+B+C)(%); E10 is E0((A+B)+C)-E(A+B+C)(%); E11 is E0((A+C)+B)-E(A+B+C)(%); E12 is E0(A+(B+C))-E(A+B+C)(%)

[0141] In Table 1 and Table 2:

[0142] E(A) represents the actual fresh weight survival rate of the A component alone at a given dose.

[0143] E(B) represents the actual fresh weight survival rate of B component alone at a given dose.

[0144] E(C) represents the actual fresh weight survival rate of C component alone at a given dose.

[0145] E(A+B) represents the actual fresh weight survival rate of the A+B two-component mixture at a given dose.

[0146] E(A+C) represents the actual fresh weight survival rate of the A+C two-component mixture at a given dose.

[0147] E(B+C) represents the actual fresh weight survival rate of the B+C two-component mixture at a given dose.

[0148] E(A+B+C) represents the actual fresh weight survival rate of the mixture of A+B+C at a given dose.

[0149] E0(A+B+C) represents the theoretical fresh weight survival rate of the mixture of A+B+C at a given dose.

[0150] E0((A+B)+C) represents the theoretical fresh weight survival rate of the A+B two-component mixture as a whole and the C two-component mixture at a given dose.

[0151] E0((A+C)+B) represents the theoretical fresh weight survival rate of the A+C two-component mixture as a whole and the B two-component mixture at a given dose.

[0152] E0(A+(B+C)) represents the theoretical fresh weight survival rate of the B+C two-component mixture as a whole with the A two-component mixture at a given dose.

[0153] The results of the bio-efficacy experiments show that the mixture of sulfonepyraclostrobin, difluanid and fluazifop has a significant synergistic effect.

[0154] Field efficacy trials

[0155] This experiment was conducted in a wheat field in Nanxinzhuang Village, Shangcai County, Zhumadian City, Henan Province, following a previous crop of corn. The experimental site had uniform fertility and was flat. The soil had clayey soil with medium fertility and moderate moisture. Guanmai No. 1 was sown, and the wheat fields were also seeded with annual monocotyledonous and dicotyledonous weeds harvested the previous year, including Aegilops tauschii, Lolium multiflorum, wild oats, bromegrass, Alopecurus scabra, sedge grass, Veronica officinalis, Glechoma longituba, Artemisia selengensis, Shepherd's purse, Herba Lycopodii, Aesculus serrata, and Chickweed, distributed evenly throughout the field.

[0156] Application time: Apply the pesticide after wheat is sown and before it emerges. The specific time is the afternoon of October 7, 2023.

[0157] Application conditions: sunny day with temperature between 10℃ and 23℃ on the day of application.

[0158] The test agents were provided by Anhui Fengle Agrochemical Co., Ltd., and the control agents included 40% diflufenacil suspension (commercially available), 30% diflufenacil (emulsifiable concentrate) (commercially available), and 480 g / L trifluralin emulsifiable concentrate (self-prepared).

[0159] The test adopted the soil spray method, and sprayed according to the dosage in the table below. At the same time, clean water spray was set as a control. Before spraying, 4 points were randomly selected in each plot, each point was 0.25㎡, and the average number of seedlings of monocotyledonous and dicotyledonous weeds and the average number of weed seedlings in the clean water control were investigated 20 days and 60 days after spraying to calculate the control effect. The fresh weight control effect of weeds was calculated 60 days later.

[0160]

[0161] CK is the fresh weight of the blank control area; PT is the fresh weight of residual weeds in the treatment area.

[0162] The test results are shown in Table 3:

[0163] Table 3. Blocking efficacy test on monocotyledonous and dicotyledonous weeds in wheat fields.

[0164]

[0165]

[0166] As shown in the table above, the combination of pyraclostrobin, diflufenac, and trifluralin was superior to single agents in blocking both monocotyledonous and dicotyledonous weeds in wheat fields, with a blocking effect lasting over 60 days, truly achieving a one-time application for a full season. Within the test dosage range, there were no adverse effects on wheat seedling emergence or subsequent growth.

[0167] It should be noted that the present application is not limited to the above-mentioned embodiments. The above-mentioned embodiments are merely examples, and any embodiments having substantially the same structure and effect as the technical concept within the scope of the present application are all included in the technical scope of the present application. In addition, without departing from the scope of the present application, any other embodiments that can be conceived by those skilled in the art and that combine some of the constituent elements in the embodiments are also included in the scope of the present application.

Claims

1. A ternary herbicidal composition containing sulfonepyraclostrobin, characterized in that: Contains herbicidally effective amounts of sulfonepyraclostrobin, difluanid and trifluralin.

2. The ternary herbicidal composition containing sulfonepyraclostrobin according to claim 1, characterized in that: The mass ratio of sulfonepyraclostrobin, difluanid and trifluralin is 1-500:1-200:2-3000.

3. The ternary herbicidal composition containing sulfonepyraclostrobin as claimed in claim 2, characterized in that: The mass ratio of sulfonepyraclostrobin, diflufenac and trifluralin is 20-200:1-150:30-2000; Preferably, the mass ratio of sulfonepyraclostrobin, difluanid and trifluralin is 45-180:33.75-135:270-1080.

4. A mixed herbicide, characterized in that: The herbicidal composition comprises the ternary herbicidal composition according to any one of claims 1 to 3.

5. The mixed herbicide according to claim 4, characterized in that It also contains at least one pesticide-acceptable adjuvant and / or carrier.

6. The mixed herbicide according to claim 4, wherein In the mixed herbicide, the mass proportion of the ternary herbicidal composition is 1 to 95%.

7. The mixed herbicide according to claim 6, wherein In the mixed herbicide, the mass proportion of the ternary herbicidal composition is 10 to 80%.

8. The mixed herbicide according to claim 4, wherein The formulation of the mixed herbicide is one of water suspension concentrate, suspoemulsion, wettable powder, emulsifiable concentrate, water dispersible granules, water emulsion, microemulsion or microcapsule suspension.

9. Use of the herbicidal composition according to any one of claims 1 to 3 or the mixed herbicide according to any one of claims 4 to 8 in controlling crop weeds; Preferably, the crop is wheat; Preferably, the weeds are at least one of Aegilops tauschii, Lolium multiflorum, wild oats, Bromus, Alopecurus mume, Alopecurus scabra, Veronica officinalis, Clary glomerata, Artemisia selengensis, Shepherd's purse, Herba Lycopodii, Aesculus fragrans, and Chickweed.

10. A method for preventing and controlling the growth of crop weeds, characterized in that: An effective amount of the herbicidal composition according to any one of claims 1 to 3 or the mixed herbicide according to any one of claims 4 to 8 is applied to weed seeds or weed-growing areas.

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