Traditional Chinese medicine composition for treating ear diseases and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating ear diseases, which comprises the following components in parts by weight: 15-20 parts of bupleurum chinense, 10-15 parts of vinegar-processed rhizoma cyperi, 10-15 parts of ligusticum wallichii, 10-15 parts of bran-fried fructus aurantii, 10-15 parts of vinegar-processed radix curcumae, 25-30 parts of cortex albiziae, 10-15 parts of radix paeoniae alba, 25-30 parts of radix puerariae, 25-30 parts of rhizoma acori graminei, 15-20 parts of fried peach kernel, 15-20 parts of safflower, 20-25 parts of salvia miltiorrhiza, 40-45 parts of magnet and 30-35 parts of calcined oyster shell. , 15-20 parts of fried spina date seeds, 20-25 parts of radix pseudostellariae, 20-25 parts of processed polygala tenuifolia and 6-10 parts of licorice slices. The invention belongs to the technical field of ear disease treatment, and particularly relates to a traditional Chinese medicine composition for treating ear diseases and a preparation method thereof, the traditional Chinese medicine composition is developed by combining clinical characteristics of tinnitus, deafness, dizziness and the like and applying knowledge of traditional Chinese medicine and pharmacy, and the traditional Chinese medicine composition is suitable for patients with tinnitus, insomnia, vexation and the like conforming to the traditional Chinese medicine syndromes caused by liver depression, qi stagnation, blood stasis and restlessness.

Description

Technical Field

[0001] The present invention belongs to the technical field of ear disease treatment, and in particular relates to a traditional Chinese medicine composition for treating ear diseases and a preparation method thereof. Background Art

[0002] Tinnitus and deafness refer to the patient's perception of ringing in the ears or brain, such as the chirping of cicadas, roaring sounds, or the sound of the tide. Deafness refers to varying degrees of hearing loss, or even complete absence. Tinnitus can be accompanied by deafness, or deafness can develop from tinnitus. Although the clinical manifestations and associated symptoms of the two conditions differ, they share many similarities in their etiology and pathogenesis, both of which are closely related to the kidneys. Tinnitus and deafness can be common clinical symptoms, often seen in a variety of medical conditions across various disciplines, and can also be a separate ear disease. Because tinnitus is not an independent disease, the causes of tinnitus are complex and are still under discussion in the medical community, making it difficult to unify the classification of tinnitus.

[0003] Tinnitus has serious consequences: It affects emotions: Long-term severe tinnitus can cause people to feel upset, worried, anxious, depressed, and have other emotional changes. Some people would rather not hear at all than have tinnitus, which can reach an unbearable level.

[0004] Impact on work: Because I can't hear others clearly, especially leaders and teachers, and I endure the great pain brought by tinnitus, but I often can't be understood by others. As a result, my work efficiency decreases and I gradually lose interest in work and study.

[0005] Impact on family life: Among the impacts of tinnitus on people, long-term medical treatment and medication due to tinnitus can lead to financial losses and even huge financial pressure. If family members do not understand, it will affect family harmony.

[0006] Impact on hearing: Very loud tinnitus can interfere with what is being heard, and one can often hear voices but cannot distinguish what others are saying;

[0007] Sleep disturbance: Tinnitus is particularly loud in the dead of night, making it difficult to fall asleep. Even when sleep does occur, it is very shallow. Some people report being awakened by tinnitus even during a shallow sleep. Even after waking in the middle of the night, the tinnitus continues, leaving them restless and unable to sleep.

[0008] "Suwen·Jue Lun" says: "The symptoms of Shaoyang Jue are sudden deafness, cheek swelling and heat"; Tang Zonghai's "Medical Abilities" written a hundred years ago says: "Although the kidney orifices can distinguish sounds and the sounds circulate around the ears, it is the gallbladder meridian. People of that time did not know that clearing wood and fire will nourish the kidneys and make them bright"; "Gujin Yitong·Ear Diseases" says: "Worry and anxiety will hurt the heart, and loss of heart blood will inevitably lead to tinnitus and deafness." Therefore, when treating ear diseases, use Chaihu to disperse liver and gallbladder stagnation, Taohong Siwu Decoction to promote blood circulation and remove blood stasis as a supplement, and Suanzaoren Decoction to nourish blood and liver, and soothe the mind. Summary of the Invention

[0009] In view of the above situation, in order to overcome the defects of the prior art, the purpose of the present invention is to provide a traditional Chinese medicine composition for the treatment of ear diseases and a preparation method thereof. It is developed by combining the clinical characteristics of tinnitus, deafness, dizziness, etc. and applying the knowledge of traditional Chinese medicine. It is suitable for patients with tinnitus, insomnia, irritability, etc. caused by liver depression and qi stagnation, blood stasis, and restlessness that meet the above-mentioned traditional Chinese medicine symptoms.

[0010] The technical solution adopted by the present invention is as follows: A traditional Chinese medicine composition for treating ear diseases comprises the following components in parts by weight: 15-20 parts of northern bupleurum, 10-15 parts of vinegar-cooked cyperus, 10-15 parts of ligusticum chuanxiong, 10-15 parts of stir-fried fructus aurantii with bran, 10-15 parts of vinegar-cooked turmeric, 25-30 parts of julibrissin bark, 10-15 parts of white peony root, 25-30 parts of kudzu root, 25-30 parts of calamus, 15-20 parts of stir-fried peach kernel, 15-20 parts of safflower, 20-25 parts of salvia miltiorrhiza, 40-45 parts of magnetite, 30-35 parts of calcined oyster shell, 15-20 parts of stir-fried spiny jujube kernel, 20-25 parts of pseudoginseng, 20-25 parts of processed polygala tenuifolia, and 6-10 parts of liquorice slices.

[0011] Furthermore, the present invention provides a traditional Chinese medicine composition for treating ear diseases, comprising the following components in parts by weight: 17-18 parts of northern bupleurum, 12-13 parts of vinegar-cooked cyperus, 12-13 parts of ligusticum chuanxiong, 12-13 parts of stir-fried fructus aurantii with bran, 12-13 parts of vinegar-cooked turmeric, 27-28 parts of julibrissin bark, 12-13 parts of white peony root, 27-28 parts of kudzu root, 27-28 parts of calamus, 17-18 parts of stir-fried peach kernel, 17-18 parts of safflower, 22-23 parts of salvia miltiorrhiza, 42-43 parts of magnetite, 32-33 parts of calcined oyster shell, 17-18 parts of stir-fried spiny jujube kernel, 22-23 parts of pseudoginseng, 22-23 parts of processed polygala tenuifolia, and 7-9 parts of liquorice tablets.

[0012] Furthermore, the present invention provides a traditional Chinese medicine composition for treating ear diseases, comprising the following components in parts by weight: 17.5 parts of northern bupleurum, 12.5 parts of vinegar-cooked cyperus, 12.5 parts of chuanxiong, 12.5 parts of stir-fried fructus aurantii with bran, 12.5 parts of vinegar-cooked turmeric, 27.5 parts of julibrissin bark, 12.5 parts of white peony root, 27.5 parts of kudzu root, 27.5 parts of calamus, 17.5 parts of stir-fried peach kernel, 17.5 parts of safflower, 22.5 parts of salvia miltiorrhiza, 42.5 parts of magnetite, 32.5 parts of calcined oyster shell, 17.5 parts of stir-fried spiny jujube kernel, 22.5 parts of pseudoginseng, 22.5 parts of processed polygala tenuifolia, and 8 parts of liquorice tablets.

[0013] Furthermore, the present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0014] Step 1:

[0015] Mix Bupleurum chinense, Albizzia julibrissin bark, stir-fried peach kernel, safflower, lodestone, calcined oyster shell, processed Polygala tenuifolia, and licorice slices, add 8 times the amount of water, and boil three times for 2 hours each time.

[0016] Step 2:

[0017] Filter the medicinal liquid after each decoction, combine the filtrates, and concentrate the filtrates to an extract with a relative density of 1.251.30. This step is carried out at a temperature of 60°C to 65°C;

[0018] Step 3:

[0019] Grind vinegar-soaked Cyperus rotundus, Chuanxiong rhizome, stir-fried Citrus aurantium with bran, vinegar-soaked Curcuma aromatica, white peony root, Pueraria root, Acorus calamus, Salvia miltiorrhiza, stir-fried Ziziphus jujuba seeds, and Pseudostellaria pseudoginseng into fine powder;

[0020] Step 4:

[0021] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0022] Step 5:

[0023] Making pellets from the fine powder mixed after pulverization in step 4;

[0024] Step 6:

[0025] The pellets were dried at 60°C.

[0026] After adopting the above technical solution, the present invention has the following beneficial effects: providing a traditional Chinese medicine composition for treating ear diseases and a preparation method thereof, wherein the components are made into pills, which are more convenient and easier to carry than decoctions, and the prescription has the functions of soothing the liver and relieving depression, calming the mind and tranquilizing the nerves, and is suitable for patients with tinnitus, deafness and other symptoms consistent with the above traditional Chinese medicine syndromes;

[0027] Among them, Bupleurum chinense relieves liver stagnation and relieves depression, and Carthami promotes blood circulation, unblocks menstruation and disperses blood stasis, which are both the main medicines. Vinegar and Cyperus rotundus regulate qi and relieve liver and relieve pain, while Chuanxiong promotes blood circulation and qi to relieve pain. The combination of these two medicines helps Bupleurum chinense to relieve stagnation in the liver meridian and enhances the effects of promoting qi, activating blood circulation and relieving pain, and they are all the minister medicines; stir-fried Citrus aurantium regulates qi and relieves stagnation, white peony root and licorice nourish blood and soften the liver, relieve urgency and relieve pain, and they are all adjuvant medicines; licorice harmonizes all the medicines and is the guiding medicine. The combination of various medicines can play the role of soothing the liver, promoting qi, activating blood circulation and relieving pain; Chinese jujube seeds are paired with processed Polygala tenuifolia, which, with its sweet and sour nature, enter the heart and liver meridians, nourish blood and replenish the liver, calm the mind and soothe the nerves; assisted by the pungent and dispersing properties of Chuanxiong, it regulates liver blood and soothes liver qi, and when combined with a large amount of Chinese jujube seeds, the pungent and dispersing properties and sour and astringent properties are used together, combining blood tonification and blood circulation, which has the effect of nourishing blood and regulating the liver; vinegar turmeric, jujube bark, peach kernel and salvia miltiorrhiza are added to enhance their ability to promote qi and blood circulation; Pueraria root is paired with Pseudostellaria baicalensis to enhance the effect of replenishing qi and strengthening the spleen The efficacy of the formula is combined with Acorus calamus: its pungent flavor and warm nature enter the heart and stomach meridians, and its functions include aromatic dehumidification, phlegm-removing and oil-reducing, brightening the eyes and ears, and opening the nine orifices. Acorus calamus is a sacred medicine for opening the ears, and has the functions of resolving phlegm, opening the orifices, and unblocking the heart qi; its fragrance can overcome the spirit, its pungent flavor can suppress wind, its warmth can unblock the meridians, and its bitterness can dry out dampness and resolve phlegm. Its pungent and bitter properties can move upward and downward, making it good for treating tinnitus, deafness, and breath holding; it is combined with magnetite to calm the liver and suppress yang, improve hearing and eyesight, and calm the nerves; calcined oyster has astringent and firming properties, which enhances its calming and tranquilizing effect. The whole formula has the functions of soothing the liver and relieving depression, calming the heart and tranquilizing the mind, and is suitable for patients with tinnitus, deafness, and other symptoms that meet the above-mentioned TCM syndromes; this formula can quickly improve the patient's symptoms and alleviate the condition, increasing the chances of treatment for patients with tinnitus and deafness. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the present invention are clearly and completely described below. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0029] Example 1:

[0030] The invention discloses a traditional Chinese medicine composition for treating ear diseases. The composition comprises the following components in parts by weight: 15 parts of bupleurum chinense, 10 parts of vinegar-cooked cyperus rotundus, 10 parts of ligusticum chuanxiong, 10 parts of stir-fried fructus aurantii with bran, 10 parts of vinegar-cooked turmeric, 25 parts of julibrissin bark, 10 parts of white peony root, 25 parts of kudzu root, 25 parts of calamus, 15 parts of stir-fried peach kernel, 15 parts of safflower, 20 parts of salvia miltiorrhiza, 40 parts of magnetite, 30 parts of calcined oyster shell, 15 parts of stir-fried spiny jujube kernel, 20 parts of pseudoginseng, 20 parts of processed polygala tenuifolia, and 6 parts of liquorice tablets.

[0031] The present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0032] Step 1:

[0033] Mix Bupleurum chinense, Albizzia julibrissin bark, stir-fried peach kernel, safflower, lodestone, calcined oyster shell, processed Polygala tenuifolia, and licorice slices, add 8 times the amount of water, and boil three times for 2 hours each time.

[0034] Step 2:

[0035] Filter the medicinal liquid after each decoction, combine the filtrates, and concentrate the filtrates to an extract with a relative density of 1.251.30. This step is carried out at a temperature of 60°C to 65°C;

[0036] Step 3:

[0037] Grind vinegar-soaked Cyperus rotundus, Chuanxiong rhizome, stir-fried Citrus aurantium with bran, vinegar-soaked Curcuma aromatica, white peony root, Pueraria root, Acorus calamus, Salvia miltiorrhiza, stir-fried Ziziphus jujuba seeds, and Pseudostellaria pseudoginseng into fine powder;

[0038] Step 4:

[0039] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0040] Step 5:

[0041] Making pellets from the fine powder mixed after pulverization in step 4;

[0042] Step 6:

[0043] The pellets were dried at 60°C.

[0044] Example 2:

[0045] The invention discloses a traditional Chinese medicine composition for treating ear diseases. The composition comprises the following components in parts by weight: 17.5 parts of bupleurum chinense, 12.5 parts of vinegar-cooked cyperus rotundus, 12.5 parts of ligusticum chuanxiong, 12.5 parts of stir-fried fructus aurantii with bran, 12.5 parts of vinegar-cooked turmeric, 27.5 parts of julibrissin bark, 12.5 parts of white peony root, 27.5 parts of kudzu root, 27.5 parts of calamus, 17.5 parts of stir-fried peach kernel, 17.5 parts of safflower, 22.5 parts of salvia miltiorrhiza, 42.5 parts of magnetite, 32.5 parts of calcined oyster shell, 17.5 parts of stir-fried spiny jujube kernel, 22.5 parts of pseudoginseng, 22.5 parts of processed polygala tenuifolia, and 8 parts of liquorice tablets.

[0046] The present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0047] Step 1:

[0048] Mix Bupleurum chinense, Albizzia julibrissin bark, stir-fried peach kernel, safflower, lodestone, calcined oyster shell, processed Polygala tenuifolia, and licorice slices, add 8 times the amount of water, and boil three times for 2 hours each time.

[0049] Step 2:

[0050] Filter the medicinal liquid after each decoction, combine the filtrates, and concentrate the filtrates to an extract with a relative density of 1.251.30. This step is carried out at a temperature of 60°C to 65°C;

[0051] Step 3:

[0052] Grind vinegar-soaked Cyperus rotundus, Chuanxiong rhizome, stir-fried Citrus aurantium with bran, vinegar-soaked Curcuma aromatica, white peony root, Pueraria root, Acorus calamus, Salvia miltiorrhiza, stir-fried Ziziphus jujuba seeds, and Pseudostellaria pseudoginseng into fine powder;

[0053] Step 4:

[0054] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0055] Step 5:

[0056] Making pellets from the fine powder mixed after pulverization in step 4;

[0057] Step 6:

[0058] The pellets were dried at 60°C.

[0059] Example 3:

[0060] The invention discloses a traditional Chinese medicine composition for treating ear diseases. The composition comprises the following components in parts by weight: 20 parts of northern bupleurum, 15 parts of vinegar-cooked cyperus, 15 parts of ligusticum chuanxiong, 15 parts of stir-fried fructus aurantii with bran, 15 parts of vinegar-cooked turmeric, 30 parts of julibrissin bark, 15 parts of white peony root, 30 parts of kudzu root, 30 parts of calamus, 20 parts of stir-fried peach kernel, 20 parts of safflower, 25 parts of salvia miltiorrhiza, 45 parts of magnetite, 35 parts of calcined oyster shell, 20 parts of stir-fried spiny jujube kernel, 25 parts of pseudoginseng, 25 parts of processed polygala tenuifolia, and 10 parts of liquorice tablets.

[0061] The present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0062] Step 1:

[0063] Mix Bupleurum chinense, Albizzia julibrissin bark, stir-fried peach kernel, safflower, lodestone, calcined oyster shell, processed Polygala tenuifolia, and licorice slices, add 8 times the amount of water, and boil three times for 2 hours each time.

[0064] Step 2:

[0065] Filter the medicinal liquid after each decoction, combine the filtrates, and concentrate the filtrates to an extract with a relative density of 1.251.30. This step is carried out at a temperature of 60°C to 65°C;

[0066] Step 3:

[0067] Grind vinegar-soaked Cyperus rotundus, Chuanxiong rhizome, stir-fried Citrus aurantium with bran, vinegar-soaked Curcuma aromatica, white peony root, Pueraria root, Acorus calamus, Salvia miltiorrhiza, stir-fried Ziziphus jujuba seeds, and Pseudostellaria pseudoginseng into fine powder;

[0068] Step 4:

[0069] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0070] Step 5:

[0071] Making pellets from the fine powder mixed after pulverization in step 4;

[0072] Step 6:

[0073] The pellets were dried at 60°C.

[0074] The above description of the present invention and its embodiments is non-limiting, and the actual structure is not limited thereto. In short, if a person skilled in the art is inspired by the above description and, without departing from the purpose of the present invention, designs a structure and embodiment similar to the technical solution without creatively designing, they shall fall within the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for treating ear diseases, characterized in that: The invention comprises the following components in parts by weight: 15-20 parts of northern bupleurum, 10-15 parts of vinegar-cooked cyperus, 10-15 parts of ligusticum chuanxiong, 10-15 parts of stir-fried fructus aurantii with bran, 10-15 parts of vinegar-cooked turmeric, 25-30 parts of julibrissin bark, 10-15 parts of white peony root, 25-30 parts of kudzu root, 25-30 parts of calamus, 15-20 parts of stir-fried peach kernel, 15-20 parts of safflower, 20-25 parts of salvia miltiorrhiza, 40-45 parts of magnetite, 30-35 parts of calcined oyster shell, 15-20 parts of stir-fried spiny jujube kernel, 20-25 parts of pseudoginseng, 20-25 parts of processed polygala tenuifolia, and 6-10 parts of liquorice slices.

2. The Chinese medicine composition for treating ear diseases according to claim 1, characterized in that The invention comprises the following components in parts by weight: 17-18 parts of bupleurum chinense, 12-13 parts of vinegar-cooked cyperus rotundus, 12-13 parts of ligusticum chuanxiong, 12-13 parts of stir-fried fructus aurantii with bran, 12-13 parts of vinegar-cooked turmeric, 27-28 parts of julibrissin bark, 12-13 parts of white peony root, 27-28 parts of kudzu root, 27-28 parts of calamus, 17-18 parts of stir-fried peach kernel, 17-18 parts of safflower, 22-23 parts of salvia miltiorrhiza, 42-43 parts of magnetite, 32-33 parts of calcined oyster shell, 17-18 parts of stir-fried spiny jujube kernel, 22-23 parts of pseudoginseng, 22-23 parts of processed polygala tenuifolia, and 7-9 parts of liquorice slices.

3. The Chinese medicine composition for treating ear diseases according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 17.5 parts of bupleurum chinense, 12.5 parts of vinegar-cooked cyperus rotundus, 12.5 parts of ligusticum chuanxiong, 12.5 parts of stir-fried fructus aurantii with bran, 12.5 parts of vinegar-cooked turmeric, 27.5 parts of julibrissin bark, 12.5 parts of white peony root, 27.5 parts of kudzu root, 27.5 parts of calamus, 17.5 parts of stir-fried peach kernel, 17.5 parts of safflower, 22.5 parts of salvia miltiorrhiza, 42.5 parts of magnetite, 32.5 parts of calcined oyster shell, 17.5 parts of stir-fried spiny jujube kernel, 22.5 parts of pseudoginseng, 22.5 parts of processed polygala tenuifolia, and 8 parts of liquorice slices.

4. A method for preparing a traditional Chinese medicine composition for treating ear diseases according to any one of claims 1 to 3, characterized in that: The following steps are involved: Step 1: Mix Bupleurum chinense, Albizzia julibrissin bark, stir-fried peach kernel, safflower, lodestone, calcined oyster shell, processed Polygala tenuifolia, and licorice slices, add 8 times the amount of water, and boil three times for 2 hours each time. Step 2: Filter the medicinal liquid after each decoction, combine the filtrates, and concentrate the filtrates to an extract with a relative density of 1.251.

30. This step is carried out at a temperature of 60°C to 65°C; Step 3: Grind vinegar-soaked Cyperus rotundus, Chuanxiong rhizome, stir-fried Citrus aurantium with bran, vinegar-soaked Curcuma aromatica, white peony root, Pueraria root, Acorus calamus, Salvia miltiorrhiza, stir-fried Ziziphus jujuba seeds, and Pseudostellaria pseudoginseng into fine powder; Step 4: Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly; Step 5: Making pellets from the fine powder mixed after pulverization in step 4; Step 6: The pellets were dried at 60°C.