Deep brain stimulator for treating heart and cerebral vessels and method of use

Abstract

The invention relates to the technical field of deep brain electrical stimulators, and discloses a deep brain electrical stimulator for treating heart and cerebral vessels, which comprises an in-vitro stimulation generator and an extension wire, the device further comprises a head fixing assembly and a control assembly, the left side of the in-vitro stimulation generator is movably connected with the head fixing assembly, the control assembly is installed on the upper portion in the in-vitro stimulation generator, the output end of the control assembly is connected with an extension wire, the head fixing assembly comprises a spring belt, and the spring belt is arranged on the left side of the in-vitro stimulation generator. Fixing plates are connected between the spring belts in a central symmetry mode, mounting boxes are movably connected to the opposite sides of the fixing plates, and rubber plates are movably connected to the opposite sides of the mounting boxes; through the arrangement of the spring belt and the mounting box, the electrode can be more tightly attached to the skull of a patient, so that the stability of the electrode is improved, the situation that the treatment effect is affected by displacement or falling of the electrode is avoided, meanwhile, the spring belt can be adjusted according to the shape and size of the head of the patient, and a more personalized fixing mode is provided.

Description

Technical Field

[0001] The present invention relates to the technical field of deep brain stimulators, and in particular to a deep brain stimulator for treating cardiovascular and cerebrovascular diseases and a method of use. Background Art

[0002] Cardiovascular and cerebrovascular diseases are often accompanied by disorders of brain neural activity. Therefore, when treating them, a deep brain stimulator can be chosen for treatment. The deep brain stimulator (DBS) implants electrodes into specific deep brain nuclei and sends electrical stimulation signals to these subthalamic nuclei (STN) or globus pallidus internal nucleus to regulate the excitability of neurons, thereby regulating the patient's neural activity disorder and improving the patient's motor function.

[0003] Existing deep brain stimulators mostly use a single fixing glue or tape to fix the electrodes to the patient's skull during use. During long-term treatment or when the patient is active, this cannot provide sufficient stability, causing the electrodes to shift or fall off, thereby affecting the treatment effect. At the same time, if the electrodes are stuck to the patient's skin for a long time, the risk of skin damage and infection increases.

[0004] Therefore, to address the problem that the above-mentioned deep brain stimulator cannot provide sufficient stability during long-term treatment or when the patient is active, causing the electrodes to shift or fall off, thereby affecting the treatment effect, a deep brain stimulator for treating cardiovascular and cerebrovascular diseases can be designed. Summary of the Invention

[0005] In order to overcome the problem that deep neuralgia stimulators cannot provide sufficient stability during long-term treatment or when patients are active, resulting in electrode deviation or detachment, thus affecting the treatment effect.

[0006] The technical solution of the present invention is: a deep brain electrical stimulator for treating cardiovascular and cerebrovascular diseases, including an external stimulation generator and an extension wire; also including a head fixing component and a control component, the left side of the external stimulation generator is movably connected to the head fixing component, the control component is installed above the external stimulation generator, the output end of the control component is connected to the extension wire, the head fixing component includes a spring belt, the spring belt is arranged on the left side of the external stimulation generator, a fixing plate is symmetrically connected between the spring belts, the opposite side of the fixing plate is movably connected to the installation box, and the opposite side of the installation box is movably connected to the rubber plate.

[0007] Preferably, the spring belt is sleeved on the patient's head, and the rubber plate 302 and the patient's head are pressed against each other, thereby improving the comfort of use.

[0008] Preferably, a connecting tube is installed in the middle position of the top of the installation box, a protective box is provided above the spring belt, a movable plate is movably connected to the bottom end of the protective box, and an arc rod is connected between the outside of the protective box and the inside of the connecting tube.

[0009] Preferably, the control component includes a sponge pad, which is sleeved on the outer end of the extension wire close to the side of the protective box. Velcro is installed on the surface of the rear side of the in vitro stimulation generator. The output end of the extension wire is connected to an electrode sheet, and the electrode sheet is movably connected to the protective box and the installation box.

[0010] Preferably, the output end of the electrode sheet is connected to an electrode rod, and the electrode rod is arranged in the middle position of the bottom end of the protective box, and an anti-folding ring is sleeved on the outer side of the end of the extension wire close to the in vitro stimulation generator.

[0011] Preferably, a mounting block is installed inside the top of the in vitro stimulation generator, and the extension wire runs through the mounting block. A rubber ring is sleeved on the outer side of the extension wire near the mounting block.

[0012] Preferably, a connecting frame is provided on the left side of the mounting block, a conducting block is provided at the bottom end of the connecting frame, and the extension wire runs through the conducting block.

[0013] A method for using a deep brain stimulator for treating cardiovascular and cerebrovascular diseases comprises the deep brain stimulator for treating cardiovascular and cerebrovascular diseases as described above, and the steps are as follows:

[0014] The first step is to perform cardiovascular and cerebrovascular neuroimaging on the patient to accurately determine the target stimulation area in the brain and the surrounding tissue conditions, providing accurate information for electrode implantation. Based on the patient's imaging structural report, the target site for electrode implantation is determined, and the patient undergoes cranial drilling surgery.

[0015] The second step is to install the stereotactic frame on the patient's head and fix it, perform cranial drilling surgery on the patient, select an electrode rod of appropriate length, and slowly implant the electrode rod along the guide of the stereotactic frame to the target point according to the drilling position. After the electrode rod is implanted in place, install the electrode sheet in the corresponding protective box or rubber plate, and sleeve the spring belt on the patient's head. The rubber plate and the patient's head are offset to improve their comfort. The protective box or rubber plate is fixed to the patient's skull;

[0016] In the third step, the extension wire connected to the electrode is led out of the body through a subcutaneous tunnel and connected to a pre-prepared external stimulation generator, and the connection site is properly protected; after the operation is completed, the device connection status, electrode position and patient's vital signs are checked again through imaging.

[0017] Preferably, the cardiovascular and cerebrovascular neurological imaging examination method is CT scanning, and after the scanning, the image is reconstructed and processed using a filtered back projection method.

[0018] Preferably, the CT scan starts the CT device and performs a tomographic scan of the patient's brain through X-rays. After the scan, the image is reconstructed using a filtered back projection method. The specific calculation formula is as follows:

[0019] Projection process

[0020]

[0021] p(s,θ) is the projection data of the object in the direction of angle θ, s is the position coordinate of the projection line in this direction, and δ is the integral of the projection line;

[0022] Filtering process

[0023] q(s,θ)=F ―1 [|ω|F[p(s,θ)]]

[0024] F is the Fourier transform, F ―1 represents the inverse Fourier transform;

[0025] Back-projection process

[0026]

[0027] f(x,y) is the reconstructed image.

[0028] The beneficial effects of the present invention are as follows: with the arrangement of the spring belt and the mounting box, the electrodes can fit more closely to the skull of the patient, thereby improving the stability of electrode fixation and preventing displacement or detachment of the electrodes that may affect the therapeutic effect. At the same time, the spring belt can be adjusted according to the shape and size of the patient's head, thereby providing a more personalized fixation method. With the cooperation of the rubber plate and the spring belt, the patient's comfort is enhanced, the pain and discomfort caused by improper fixation are reduced, the risk of skin damage and infection is reduced, and the wearing safety is improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 Shown is a schematic diagram of the first three-dimensional structure of the deep brain stimulator for treating cardiovascular and cerebrovascular diseases of the present invention;

[0030] Figure 2 Shown is a schematic diagram of a second three-dimensional structure of the deep brain stimulator for treating cardiovascular and cerebrovascular diseases of the present invention;

[0031] Figure 3 Shown is a schematic diagram of the third stereoscopic structure of the deep brain stimulator for treating cardiovascular and cerebrovascular diseases of the present invention;

[0032] Figure 4 Shown is a schematic diagram of the cross-sectional three-dimensional structure of the head fixation component of the deep brain stimulator for treating cardiovascular and cerebrovascular diseases of the present invention;

[0033] Figure 5 Shown is a bottom-up perspective structural diagram of the head fixation assembly of the deep brain stimulator for treating cardiovascular and cerebrovascular diseases of the present invention;

[0034] Figure 6 Shown is a schematic diagram of the cross-sectional three-dimensional structure of the control component of the deep brain stimulator for treating cardiovascular and cerebrovascular diseases of the present invention.

[0035] Explanation of the accompanying reference numerals: 1. In vitro stimulation generator; 2. Extension wire; 301. Spring belt; 302. Fixing plate; 303. Mounting box; 304. Rubber plate; 305. Connecting tube; 306. Protective box; 307. Movable plate; 308. Arc rod; 401. Sponge pad; 402. Velcro; 403. Electrode sheet; 404. Electrode rod; 405. Anti-folding ring; 406. Mounting block; 407. Rubber ring; 408. Connecting frame; 409. Conducting block. DETAILED DESCRIPTION

[0036] The present invention will be further described below with reference to the accompanying drawings and examples.

[0037] See also Figure 1 - Figure 6 The present invention provides an embodiment: a deep brain electrical stimulator for treating cardiovascular and cerebrovascular diseases, comprising an external stimulation generator 1 and an extension wire 2; further comprising a head fixing component and a control component, wherein the left side of the external stimulation generator 1 is movably connected to the head fixing component, a control component is installed above the external stimulation generator 1, and an output end of the control component is connected to the extension wire 2, the head fixing component comprises a spring belt 301, the spring belt 301 is arranged on the left side of the external stimulation generator 1, a fixing plate 302 is centrally symmetrically connected between the spring belts 301, an installation box 303 is movably connected to the opposite side of the fixing plate 302, and a rubber plate 304 is movably connected to the opposite side of the installation box 303.

[0038] See also Figure 2 - Figure 4 In this embodiment, a connecting tube 305 is installed in the middle position of the top of the installation box 303, a protective box 306 is provided above the spring belt 301, and the bottom end of the protective box 306 is movably connected to a movable plate 307. An arc rod 308 is connected between the outside of the protective box 306 and the inside of the connecting tube 305. A mounting block 406 is installed inside the top of the in vitro stimulation generator 1, and the extension wire 2 passes through the mounting block 406. A rubber ring 407 is sleeved on the outside of the extension wire 2 near the end of the mounting block 406.

[0039] See also Figure 5 - Figure 6In this embodiment, the control component includes a sponge pad 401, which is sleeved on the outer end of the extension wire 2 near the side of the protective box 306. A Velcro 402 is installed on the surface of the rear side of the in vitro stimulation generator 1. The output end of the extension wire 2 is connected to an electrode sheet 403, and the electrode sheet 403 is movably connected to the protective box 306 and the installation box 303; the output end of the electrode sheet 403 is connected to an electrode rod 404, and the electrode rod 404 is arranged in the middle position of the bottom end of the protective box 306. The outer side of the extension wire 2 near the end of the in vitro stimulation generator 1 is sleeved with an anti-folding ring 405; a connecting frame 408 is provided on the left side of the installation block 406, and the connecting frame 408 is provided with a connecting frame 408. A conductive block 409 is provided at the bottom end, and the extension wire 2 passes through the conductive block 409. By selecting an electrode rod 404 of appropriate length, the electrode rod 404 is slowly implanted into the target point along the guide of the stereotactic frame according to the drilling position. After the electrode rod 404 is implanted in place, the electrode sheet 403 is installed in the corresponding protective box 306 or rubber plate 304, the spring belt 301 is sleeved on the patient's head, and the protective box 306 or rubber plate 304 fixes it on the patient's skull; the extension wire 2 connected to the electrode sheet 403 is led out of the body through a subcutaneous tunnel and connected to the pre-prepared in vitro stimulation generator 1, and the connection part is properly protected.

[0040] During operation, the patient's brain is scanned by X-rays in the CT scan. After the scan, the image is reconstructed using the filtered back projection method. The specific calculation formula is as follows:

[0041] Projection process

[0042]

[0043] Filtering process

[0044] q(s,θ)=F ―1 [|ω|F[p(s,θ)]];

[0045] Back-projection process

[0046]

[0047] The target stimulation area and surrounding tissue conditions in the brain are accurately determined. After the scan is completed, the filtered back projection method is used to reconstruct and process the image to provide accurate information for electrode implantation. Based on the patient's imaging structure report, the target electrode implantation point is determined, and the patient undergoes a cranial drilling operation. The stereotactic frame is mounted on the patient's head and fixed, and the patient undergoes a cranial drilling operation. An electrode rod 404 of appropriate length is selected and slowly implanted into the target point along the guide of the stereotactic frame according to the drilling position. After the electrode rod 404 is implanted, the electrode sheet 403 is installed in the corresponding protective box 306 or rubber plate 304. The spring band 301 is sleeved on the patient's head, and the rubber plate 304 and the patient's head are offset to improve their comfort. The protective box 306 or rubber plate 304 secures it to the patient's skull. The extension wire 2 connected to the electrode sheet 403 is led out of the body through a subcutaneous tunnel and connected to a pre-prepared external stimulation generator 1, and the connection site is properly protected. After the operation is completed, the device connection, electrode position, and patient vital signs are rechecked through imaging.

[0048] Through the above steps, the spring belt 301 and the mounting box 303 are arranged to fit more closely to the patient's skull, thereby improving the fixation stability of the electrode and preventing displacement or falling off of the electrode that may affect the treatment effect. At the same time, the spring belt 301 can be adjusted according to the shape and size of the patient's head, thereby providing a more personalized fixation method. With the cooperation of the rubber plate 304 and the spring belt 301, the patient's comfort is enhanced; this solves the problem that the deep electrical stimulator cannot provide sufficient stability during long-term treatment or when the patient is more active, resulting in electrode displacement or falling off, thereby affecting the treatment effect.

[0049] The embodiments of the present invention are described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Various changes can be made within the scope of knowledge of those skilled in the art without departing from the spirit of the present invention.

Claims

1. A deep brain electrical stimulator for treating cardiovascular and cerebrovascular diseases, comprising an external stimulation generator (1) and an extension lead (2); characterized in that: The invention also comprises a head fixing component and a control component. The left side of the external stimulation generator (1) is movably connected to the head fixing component. The control component is installed above the external stimulation generator (1). The output end of the control component is connected to an extension wire (2). The head fixing component comprises a spring belt (301). The spring belt (301) is arranged on the left side of the external stimulation generator (1). A fixing plate (302) is centrally symmetrically connected between the spring belts (301). The opposite side of the fixing plate (302) is movably connected to a mounting box (303). The opposite side of the mounting box (303) is movably connected to a rubber plate (304).

2. The deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claim 1, characterized in that: A connecting tube (305) is installed in the middle position of the top of the installation box (303), a protective box (306) is provided above the spring belt (301), a movable plate (307) is movably connected to the bottom end of the protective box (306), and an arc rod (308) is connected between the outer side of the protective box (306) and the inside of the connecting tube (305).

3. The deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claim 1, characterized in that: The control component comprises a sponge pad (401), the sponge pad (401) is sleeved on the outer end of the extension wire (2) near one side of the protection box (306), a Velcro (402) is installed on the surface of the rear side of the in vitro stimulation generator (1), the output end of the extension wire (2) is connected to an electrode sheet (403), and the electrode sheet (403) is movably connected to the protection box (306) and the installation box (303).

4. The deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claim 3, characterized in that: The output end of the electrode sheet (403) is connected to an electrode rod (404), and the electrode rod (404) is arranged at the middle position of the bottom end of the protective box (306). The outer side of the extension wire (2) close to the end of the in vitro stimulation generator (1) is sleeved with an anti-folding ring (405).

5. The deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claim 1, characterized in that: A mounting block (406) is installed inside the top of the in vitro stimulation generator (1), and the extension wire (2) passes through the mounting block (406). A rubber ring (407) is sleeved on the outer side of the extension wire (2) near the end of the mounting block (406).

6. The deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claim 5, characterized in that: A connecting frame (408) is provided on the left side of the mounting block (406), a conducting block (409) is provided at the bottom end of the connecting frame (408), and the extension wire (2) runs through the conducting block (409).

7. A method for using a deep brain stimulator for cardiovascular and cerebrovascular treatment, characterized in that: The method comprises the deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claims 1 to 6, wherein the steps are as follows: The first step is to perform cardiovascular and cerebrovascular neuroimaging on the patient to accurately determine the target stimulation area in the brain and the surrounding tissue conditions, providing accurate information for electrode implantation. Based on the patient's imaging structural report, the target site for electrode implantation is determined, and the patient undergoes cranial drilling surgery. The second step is to install the stereotactic frame on the patient's head and fix it, perform a cranial drilling operation on the patient, select an electrode rod (404) of appropriate length, and slowly implant the electrode rod (404) into the target point along the guide of the stereotactic frame according to the drilling position. After the electrode rod (404) is implanted in place, the electrode sheet (403) is installed in the corresponding protective box (306) or rubber plate (304), the spring belt (301) is sleeved on the patient's head, the spring belt (301) is sleeved on the patient's head, the rubber plate (304) and the patient's head are offset to improve the comfort of use, and the protective box (306) or rubber plate (304) is fixed to the patient's skull; In the third step, the extension wire (2) connected to the electrode sheet (403) is led out of the body through a subcutaneous tunnel and connected to a pre-prepared external stimulation generator (1), and the connection part is properly protected; after the operation is completed, the connection status of the equipment, the position of the electrodes and the patient's vital signs are checked again through imaging.

8. The method for using a deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claim 7, characterized in that: Cardiovascular and cerebrovascular neuroimaging examinations are performed using CT scans, and filtered back projection is used to reconstruct and process the images after scanning.

9. The method for using a deep brain stimulator for treating cardiovascular and cerebrovascular diseases according to claim 7, characterized in that: CT Scan: The CT device is turned on to perform a tomographic scan of the patient's brain using X-rays. After the scan, the filtered back projection method is used to reconstruct the image. The specific calculation formula is as follows: Projection process p(s,θ) is the projection data of the object in the direction of angle θ, s is the position coordinate of the projection line in this direction, and δ is the integral of the projection line; Filtering process q(s,θ)=F ―1 [|ω|F[p(s,θ)]] F is the Fourier transform, F ―1 represents the inverse Fourier transform; Back-projection process f(x,y) is the reconstructed image.

Images