Handling device for pharmaceutical production materials, handling system with handling device and apparatus for processing pharmaceutical containers

Abstract

The present invention relates to an operating device (120) for pharmaceutical production material (116), comprising a support mechanism (150), a hinge mechanism (152) including a first hinge arm section (206) and a second hinge arm section (208), at least one drive mechanism (158), and a tool (268) for acting directly or indirectly on the production material (116), wherein the operating device (120) includes a drive element (210) drivable about a first rotation axis (218), the drive element being connected to the first hinge arm section (206) in a manner without relative rotation, wherein the first hinge arm section (206) and the second hinge arm section (208) are drivable relative to each other about a second rotation axis (218). 28) The rotating components are connected to each other in a manner that is spaced apart from each other. The operating device (120) includes a guide mechanism (154) and a retainer (160). The guide mechanism has a guide body (254). The retainer includes or constitutes a tool (268), or the tool (268) is held in the retainer. A second hinged arm segment (208) is rotatable relative to the retainer (160) about a third rotation axis (252) that is spaced apart from the second rotation axis (228). At least one guide element (260) that interacts with the guide body (254) is disposed in the retainer (160). Furthermore, the present invention relates to an operating system (118) and a device (100) for handling a medical container (102).

Description

Technical Field

[0001] This invention relates to an operating device for pharmaceutical production materials, comprising tools for directly or indirectly acting on the production materials.

[0002] Furthermore, the present invention relates to an operating system for pharmaceutical production materials, comprising a frame that can be mounted on a mounting surface and an operating device of the type described above, the frame including a separating element that separates a first region and a second region.

[0003] Furthermore, the present invention relates to an apparatus for processing medical containers. Background Technology

[0004] In this type of equipment, supplied containers are weighed, filled with product, reweighed, sealed, and subsequently discharged for further processing. Accordingly, the equipment may have multiple processing stations, such as at least one weighing station, filling station, sealing station, inspection station, and / or packaging station. Containers may include, for example, tubular vials (bottles), syringes, cartridges, or ampoules. They can be stable, upright containers that can stand independently on a mounting element. Non-stable, upright objects, which are held, for example, by means of clamp-like holding elements, are also conceivable.

[0005] Containers used as primary packaging are currently considered pharmaceutical manufacturing materials; however, this is not limited to these containers. Secondary packaging, especially trays or basins that hold multiple containers, can also be considered pharmaceutical manufacturing materials, for example. Other manufacturing materials include, for example, sealing elements for closing containers. Such sealing elements can include, for example, plugs, mushroom caps, or flap caps. It is also conceivable that manufacturing materials include articles used to process containers in equipment. For example, filling needles, tubing, container retaining elements, or other manufacturing materials can be envisioned. Typically, standardized components of equipment, such as those with container-specific or container-processing-specific characteristics, can be considered manufacturing materials.

[0006] The type of operating device mentioned at the beginning is used for handling pharmaceutical production materials, particularly within this type of equipment for handling containers. In this case, the production materials are handled with a tool, which can have different implementations, depending on the production materials. The tool can act directly or indirectly on the production materials.

[0007] Mechanical manipulators for producing materials are known. For example, WO 2022 / 136537 A1 describes a manipulator in the form of an articulated arm robot (Scara) in a device for handling containers. This manipulator has proven in practice suitable for the tasks it is assigned. However, it is desirable to provide a manipulator with advantageous characteristics for handling production materials. Summary of the Invention

[0008] The object of this invention is to provide an operating device having advantageous characteristics for handling production materials. Furthermore, the object is to provide an operating system having this type of operating device and a device for handling containers using this operating system.

[0009] The above objective is achieved by an operating device for pharmaceutical production materials according to the present invention, the operating device comprising a support mechanism, a hinge mechanism including a first hinge arm segment and a second hinge arm segment, at least one drive mechanism, and a tool for acting directly or indirectly on the production material, wherein the operating device includes a drive element drivable about a first rotation axis, the drive element being connected to the first hinge arm segment in a manner without relative rotation, wherein the first hinge arm segment and the second hinge arm segment are connected to each other in a manner rotatable relative to each other about a second rotation axis, wherein the rotation axes are arranged in a spaced manner relative to each other, wherein the operating device includes a guide mechanism and a retainer, the guide mechanism having a guide body, the retainer including or constituting a tool, or the tool being held at the retainer, wherein the second hinge arm segment is rotatable relative to the retainer about a third rotation axis, the third rotation axis being arranged in a spaced manner from the second rotation axis, and at least one guide element acting in conjunction with the guide body is arranged at the retainer.

[0010] In this invention, the retainer can be driven by a rotatably driven drive element and move along the guide body of the guide mechanism. The drive element is rotatably connected to a first hinged arm section, which is rotatably connected to a second hinged arm section, which in turn is rotatably connected to the retainer. A tool for handling pharmaceutical manufacturing materials is held in the retainer. Alternatively, the retainer may include or constitute the tool. The design of the operating device particularly allows for linear motion of the tool, for example, through the rotational movement of the drive element. Rotary sealing isolation of the moving parts ensures a high hygiene standard for the operating device. Translational movement of the drive element and the hinge mechanism is particularly avoided. This avoids particle entrainment due to translational movement. Therefore, the operating device is advantageously suitable for use in equipment handling pharmaceutical containers in areas with high cleanliness levels, where the drive motor of the drive mechanism can be advantageously arranged in areas with lower cleanliness levels, and the driving force of the drive motor can be transmitted to the drive element through the area boundary. This will be discussed further below. The use of a hinge mechanism that forms a hinge arm allows the rotational motion of a drive element to be converted into the motion of a tool, especially in a linear manner, where the hinge arm segments function to some extent as an eccentric wheel mechanism due to the corresponding spacing between their axes of rotation.

[0011] When the driving force is transmitted by a drive motor arranged outside the support mechanism as described above, the support mechanism and the articulation mechanism can advantageously be given a compact configuration.

[0012] In particular, it is conceivable that a control device is provided for controlling and / or regulating the operation of the operating device.

[0013] Advantageously, the operating device does not have a drive motor for the articulated arm section at the articulation mechanism and / or the support mechanism. The drive motor for the drive mechanism is not located at the support mechanism and / or the articulation mechanism, but is instead, for example, accommodated in an area separated by a separating element of the operating system from other areas where the support mechanism and / or the articulation mechanism are located, wherein the latter area has a higher cleanliness level than the former. By omitting the drive motor at the articulation mechanism and / or the support mechanism, installation space and weight can be saved in practice. This enables a more compact structure and lower inertia, resulting in shorter cycle times when using the operating device.

[0014] Advantageously, the operating device does not have auxiliary piping for the drive motor at the articulation mechanism and / or support mechanism. Particularly advantageous is that no such auxiliary piping (e.g., electric and / or pneumatic) is guided through the support and articulation mechanisms. Eliminating auxiliary piping simplifies the structural design of the operating device. Furthermore, there is no auxiliary piping that bears the stresses caused by the rotational movement of the drive element and the articulated arm section, particularly at the articulated joint. Therefore, eliminating auxiliary piping improves the reliability of the operating device.

[0015] Because it can achieve a lighter weight and more compact installation space compared to conventional operating devices, there is no difficulty in using pharmaceutically suitable materials in the operating device according to the invention.

[0016] In particular, 316L grade stainless steel, which meets the requirements for the cleanability of the operating device, can be used as the material.

[0017] Alternatively or supplementary materials, such as pharmaceutical-grade plastics, can be used, thereby keeping the weight low, which may prove even more advantageous for short cycle times.

[0018] The guide body can, for example, be configured to extend in a straight line. For example, the tool can move downwards and upwards along the guide body. This, for example, enables the operating device to be used as a sealing device for pressing a sealing element onto or into a container. However, the invention is not currently limited thereto.

[0019] However, what can be particularly beneficial is that the tool can move in a straight line.

[0020] The location and orientation descriptions relate to the intended use of the operating device within the equipment.

[0021] The guide body can be designed as a rod or slat, for example.

[0022] The guide body may, for example, have a flat guiding surface for at least one guiding element. This enables particularly advantageous guiding characteristics.

[0023] The guide body and at least one guide element may optionally engage with each other. For example, at least one guide element engages into at least one groove at the guide body, or vice versa.

[0024] The guide body and at least one guide element are preferably made of a material suitable for pharmaceuticals and wear-resistant. For example, stainless steel is used.

[0025] At least one guiding element is, for example, a roller. The roller may roll on a flat guiding surface, for example. Alternatively, the roller may advantageously include a raised portion along its outer periphery, which may engage with a corresponding groove in the guide body.

[0026] Two or more guide elements can be provided, arranged on the opposite sides of the guide body, so that the guide body is positioned between the guide elements. This allows the retainer to be guided in a particularly reliable manner.

[0027] It can be envisioned that two guide elements abut against one side of the guide body, while other guide elements abut against the opposite side of the guide body, these other guide elements being positioned between the aforementioned guide elements with reference to the direction of movement. This ensures that the retainer can be reliably guided without tilting relative to the guide body.

[0028] Advantageously, the guide body and retainer, along with at least one guiding element disposed therein, are not covered by the housing. This allows for direct cleaning of the guide body, retainer, and guiding element, for example, by rinsing or spraying. Furthermore, the operating device can undergo VHP circulation, in which the aforementioned components are subjected to a purge atmosphere (e.g., H2O2). This preferably makes the operating device conform to the requirements of Annex 1 for Good Manufacturing Practice (GMP).

[0029] The articulated arm segments can be constructed to have different lengths. For example, it can be envisioned that the first articulated arm segment is shorter than the second articulated arm segment. In this case, the distance between the first two rotation axes is less than the distance between the second or third rotation axes.

[0030] Alternatively, it can be specified that the articulated arm segments are of the same length, or that the first articulated arm segment is shorter than the second articulated arm segment.

[0031] The support mechanism may include, for example, a support mechanism housing, in which the drive element is partially arranged, wherein the drive element is guided through at least one through opening in the support mechanism housing. In this case, the drive element is preferably rotationally sealed relative to the support mechanism housing. The sealing mechanism is or includes a rotating sealing element, such as a doppellastreifer.

[0032] Advantageously, the drive element does not have translational movement relative to the support housing.

[0033] The support mechanism housing may include, for example, a first housing component and a second housing component. For example, the first housing component may be plate-shaped, while the second housing component may be cover-shaped. The support mechanism housing may include a wall positioned between the two housing components. For example, end walls opposite each other may be provided. For example, at least one through opening may be formed in one of the end walls. The drive element may be supported at at least one end wall, for example, via a bearing mechanism in a manner rotatable about a first axis of rotation.

[0034] The bearing mechanism of the operating device according to the invention and its preferred embodiments is, for example, a rolling bearing or a sliding bearing, wherein a suitable bearing is selected by those skilled in the art as required. For rotatable components, radial supports are particularly provided. Alternatively or additionally, axial supports may be conceived. The bearing mechanism can be single-segment or multi-segment. A multi-segment bearing mechanism, for example, comprises two or more bearing elements, such as bearing rings, arranged with spacing between them.

[0035] As described above, the support mechanism advantageously lacks a drive motor. To transmit driving force to the drive element, a connecting element can be provided, for example. The operating device can have this type of connecting element associated with the drive element, which can be driven by at least one drive mechanism, wherein the connecting element engages in and is connected to the drive element within the support mechanism housing. Due to the connecting element, the drive motor can be arranged, in particular, outside the support mechanism housing. The connecting element, for example, transmits the driving force of the drive motor, which is arranged in the lower structure of the operating system, in a zone separated from the area where the support mechanism is arranged by a partition element. In this latter zone, for example, there exists a higher cleanliness level than in the former zone. This arrangement of the drive motor, for example, allows for the design of a larger and thus more load-bearing drive motor, which would be impossible if the drive motor were positioned within the support mechanism due to space and weight constraints. This improves the reliability of the operating device.

[0036] The connecting element is preferably driven in a rotating manner, wherein a bearing mechanism for rotational movement is particularly provided.

[0037] The connecting element can be connected to the drive element, for example, via a meshing part (Verzahnung). For example, meshing conical wheels have proven to be advantageous for compact configurations.

[0038] As previously mentioned, the production material may be, for example, a sealing element for a container. To operate the sealing element, the tool may include, for example, at least one pushing element acting on the sealing element, which is particularly configured to close a pharmaceutical container. The pushing element is, for example, a push rod, via which the sealing element is pressed from the receiving portion onto or into the container.

[0039] The tool can be configured as a multi-point device to enable the simultaneous processing of multiple sealing elements and containers. Accordingly, the tool may include multiple actuating elements. The actuating elements are preferably designed to be identical.

[0040] It can be proven advantageous that, in a preferred embodiment of the invention, the components of the operating device are repeated, especially in pairs. The repeated components can advantageously be designed to be identical or functionally identical, for example, symmetrical relative to each other.

[0041] For example, the guiding mechanism includes two guiding bodies.

[0042] For example, two support mechanisms are provided.

[0043] For example, two articulated mechanisms are provided, each with two articulated arm sections.

[0044] For example, two retainers and corresponding guide elements are provided therein.

[0045] For example, there are two driving elements.

[0046] Advantageously, the tool is held at two holding bodies, or the two holding bodies include or constitute the tool.

[0047] The operating device may include two connecting elements, which are connected to corresponding drive elements.

[0048] The guiding mechanism, supporting mechanism, hinge mechanism, retaining body, and driving element are positioned in a spaced manner relative to each other. Thus, the tool can be driven from two opposite sides, and is particularly arranged between the two retaining bodies.

[0049] Advantageously, at least one drive mechanism includes a drive motor for driving two drive elements, particularly indirectly via two connecting elements. For example, the drive mechanism may be coupled to the two connecting elements in a manner without relative rotation. This allows for mechanical synchronization between the connecting elements with a simple structure, and thereby mechanical synchronization between the drive elements. In practice, this enables a simple design for the operating device while ensuring that the tool's movement is reliably guided.

[0050] Alternatively, the drive mechanism may be specified to include two separate drive motors associated with corresponding connecting elements, wherein the drive motors are preferably synchronized with each other. This, for example, enables electronically synchronized operation of the drive motors. Using two drive motors improves the versatility of the operating device according to the invention.

[0051] The aforementioned objective is also achieved by an operating system for pharmaceutical manufacturing materials according to the invention, the operating system comprising: a frame that can be mounted on a mounting surface and includes, in particular, a plate-shaped partition element that separates a first zone from a second zone, wherein the first zone has a higher cleanliness level than the second zone; an operating device of the aforementioned type, wherein a support mechanism and a hinge mechanism are arranged in the first zone, wherein at least one drive mechanism is arranged in the second zone, wherein at least one connecting element of the operating device is guided through at least one through opening in the partition element.

[0052] The advantages already mentioned regarding the operating device according to the present invention can also be achieved using an operating system. Refer to the above-described embodiments.

[0053] Advantageous embodiments of the operating system according to the invention are derived from advantageous embodiments of the operating device according to the invention. Reference is also made to the embodiments described above in this regard.

[0054] Advantageously, in the operating system according to the invention, the drive mechanism, in particular the drive motor, is arranged in the second zone. The driving force is transmitted via a connecting element through a separating element to the area of ​​the first zone, so as to drive the corresponding drive element there. Advantageously, the support mechanism and / or hinge mechanism do not have a drive motor and / or auxiliary piping for this purpose, as previously described.

[0055] Zone 1 can be a cleanroom, such as Class A, B, C, or D. Separating elements can be covered by machine protection devices with corresponding walls and / or by isolation mechanisms.

[0056] Separating elements can be, for example, the platform of a frame.

[0057] The operating system may include, for example, a cylindrical support mechanism in which at least one connecting element is arranged, and the support mechanism passes through or engages with a through opening or abuts against the edge of the through opening in a first region. The support mechanism may, for example, form a housing or cover for the at least one connecting element.

[0058] Preferably, the operating system includes a sealing mechanism for sealing and isolating the through opening between the first zone and the second zone.

[0059] At least one connecting element or supporting mechanism, for example, does not involve linear movement, especially lifting movement, through the through opening. This prevents bacteria from being carried from the second zone to the first zone, thereby improving the hygiene standards of the operating system.

[0060] The operating device and operating system preferably use only rotational motion and corresponding rotary seal isolation. Preferably, there is no translational motion, such as lifting motion, during operation to avoid corresponding particle entrainment due to translational motion.

[0061] It can be stipulated that translational movement is possible, however, for example only for preparation work before actual operation, and not during operation.

[0062] In a preferred embodiment of the invention, the operating system advantageously includes at least one transport track for the sealing element and a holding element for the container to be sealed. Depending on the type of container, the holding element may be, for example, a placement element for a stably upright container or a clamping element for a non-stably upright container.

[0063] Especially in the advantageous embodiment mentioned last, the tool can move from a basic position, particularly in a linear fashion, to a pressing position, and vice versa, wherein the distance between the pushing element and the sealing element in the basic position is greater than that in the pressing position, and wherein the sealing element in the pressing position can be subjected to a force pointing toward the container. This force can press the sealing element, for example, from the receiving portion onto the container or into the container.

[0064] The apparatus for processing pharmaceutical containers according to the invention includes an operating system of the type described above, wherein the operating system includes or constitutes a sealing station for the container, and wherein at least one other processing station for the container, such as a filling station, is provided. For example, a container filled with product is supplied to a sealing element, and the sealing element is placed on or introduced into the container by means of a pushing element.

[0065] Then, the device according to the invention has the advantages and effects mentioned above in combination with the operating device and the operating system. Advantageous embodiments of the device are derived from the advantageous embodiments of the operating device and the operating system. Attached Figure Description

[0066] The following description of preferred embodiments of the present invention is provided to illustrate the invention in more detail with reference to the accompanying drawings. In the drawings:

[0067] Figure 1 An apparatus for processing pharmaceutical containers according to the invention is shown in a preferred embodiment, the apparatus comprising an operating system according to the invention having an operating device according to the invention in a corresponding preferred embodiment;

[0068] Figure 2 It shows Figure 1 A schematic diagram of the device's operating system;

[0069] Figure 3 It shows Figure 1 A partial perspective view of the operating system's operating device and supply device;

[0070] Figure 4 It shows according to Figure 3 A magnified 3D view of the operating device of detail A in the image;

[0071] Figure 5 It shows Figure 4 Details shown from different perspectives;

[0072] Figure 6 A side view of the supply device is shown, with its tools in a receiving position for sealing elements;

[0073] Figure 7 It shows Figure 6 The supply device, wherein the tool is in the handover position and the actuating element of the operating device takes a basic position; and

[0074] Figure 8 It shows the corresponding Figure 7 The view shows the pushing element taking a pressing position. Detailed Implementation

[0075] Figure 1 A schematic diagram illustrates an advantageous embodiment of the apparatus according to the invention for processing medical containers, indicated by reference numeral 100. The container 102 is currently exemplary, in part, a vial (tubular bottle) 104, in which... Figure 7 and 8 As shown in the figure. However, the invention is not limited to this type of container 102.

[0076] The device 100 allows containers 102 to be processed at multiple processing stations 106. Processing stations 106 include, for example, at least one weighing station 108 for weighing containers in an unfilled or filled state for tare and gross weight; a filling station 110 for filling containers 102 with product; and a sealing station 112. At the sealing station 112, containers can be sealed using sealing elements 114.

[0077] Sealing element 114 is currently in Figure 3 as well as Figures 6 to 8 As shown in the figure. The sealing element 114 belongs to the pharmaceutical production material 116. In view of the above, it should be understood that the present invention is not limited to the sealing element 114 as the production material 116.

[0078] The device 100 includes an operating system 118 according to the invention in a preferred embodiment, which in turn includes an operating device 120 according to the invention in a preferred embodiment. The operating device 120 is currently designed as a sealing device 122 for pressing the sealing element 114 against the container 102. Furthermore, the operating device 120 includes a storage device 124 for storing the sealing element 114 and a supply device 126 by means of which the sealing element 114 can be supplied to the sealing device 122.

[0079] For example from Figure 2 It is understood that the operating system 118 includes a frame 128, which can be positioned on a mounting surface 130 of a room, such as a laboratory. The frame 128 includes a partition element 132, which is currently designed as a plate and can in particular form a mounting element for the processing station 106. The partition element 132 can in particular be a platform of the frame 128.

[0080] Separating element 132 separates the first zone 134 from the second zone 136. The cleanliness level of the first zone 134 is higher than that of the second zone 136. In particular, the first zone 134 is a component of the cleanroom, for example, with a cleanliness level of A, B, C, or D, and the second zone 136 is arranged below the separating element 132, and thus in the lower structure 138 of the operating system 118, and also in the lower structure 138 of the device 100.

[0081] Zone 134 is preferably covered by a machine protection device or isolation mechanism 140, which can ensure the cleanliness level.

[0082] Within the first zone 134, containers 102 can be conveyed along the processing station 106 by means of a conveying system 142. Currently, the tubular bottles 104 are stably upright containers 102, such that the conveying system 142 includes a mounting element 144 ( Figure 7 and Figure 8The mounting element 144 is formed, for example, by a conveyor belt, but the invention is not limited thereto.

[0083] In the case of operating system 118 in this embodiment, the container can be positioned on the placement element 144 in a manner independent of size, such that the container axis 146 is spatially fixed. For processing to be performed at operating system 118, container 102 also has a defined position along conveying system 142.

[0084] A control device 148 is provided for controlling and / or regulating the operation of the device 100. The control device 148 can also be the control device for the operating system 118 and the operating device 120. It is advantageously connected to all controllable components of the device 100.

[0085] Especially from Figures 2 to 5 It is understood that the operating device 120 currently includes a support mechanism 150, a hinge mechanism 152, a guide mechanism 154, a load-bearing mechanism 156, a drive mechanism 158, and a retainer 160.

[0086] For example from Figure 2 and Figure 3 As can be seen, the operating system 118 currently includes two support mechanisms 150, two hinge mechanisms 152, two guide mechanisms 154, two load-bearing mechanisms 156, and two retainers 160. The correspondingly paired components are designed to be mirror-symmetrical with respect to each other, referencing the central plane 162 of the operating system 118. The components mentioned here are functionally identical. For this reason, only one of the functionally identical components will be discussed below. The relevant implementation scheme also applies to the corresponding other components.

[0087] Currently, there is only one drive mechanism 158. It includes a drive motor 164. The drive motor 164 is, for example, a servo motor or a stepper motor, and is arranged in the second section 136 and thus in the lower structure 138.

[0088] The drive motor 164 is held, for example, on the underside of the separator element 132 or at another location on the frame 128.

[0089] Currently, two through openings 166 are formed in the separating element 132. Figure 2The connecting element 168 is guided through a corresponding through opening. The connecting elements 168 are also configured to be symmetrical to each other with reference to the central plane 162. The hinge mechanism 152 can be driven via a drive motor 164 to move the retainer 160 along the guide mechanism 154. For this purpose, the operating system 118 includes a transmission mechanism 170, which is currently designed as a belt drive with a drive belt 172. The drive belt 172 is driven by the drive motor 164 and engages with the drive member 174 at the connecting element 168 in a manner without relative rotation. The drive belt 172 is, for example, a toothed belt.

[0090] Currently, the two connecting elements 168 can be driven synchronously so that the two retainers 160 move in a manner reliably guided at the guide mechanism 154. This enables a simple configuration of the operating system 118 because a separate drive motor 164 for the connecting elements 168 can be omitted.

[0091] In contrast, no drive motor is arranged in or in the support mechanism 150 and in or in the hinge mechanism 152. Furthermore, no auxiliary piping, such as electrical piping and / or pneumatic piping, is arranged in the support mechanism 150 and in the hinge mechanism 152, and in particular, they are not guided through these mechanisms 150, 152.

[0092] Overall, this results in a compact construction of the operating device 120, while achieving a relatively light weight compared to conventional operating devices. This allows for an increase in the operational cycle time achievable using the operating device, based on the compact configuration and low weight. Furthermore, the operating device 120 can be used in areas of the equipment 100 where only limited installation space is available.

[0093] In this embodiment, the support mechanism 150 forms, to some extent, a base for the hinge mechanism 152, which itself forms the hinge arm 176. In this example, the support mechanism 150 is placed on top of the columnar support mechanism 156. Figure 2 and Figure 3 ).

[0094] In different implementations, the support mechanism 150 may be arranged directly on the partition element 132, for example.

[0095] The support mechanism 156 forms a housing 178 for the connecting element 168 and surrounds the connecting element in the circumferential direction.

[0096] Currently, the support mechanism 156 rests against the edge 180 of the through opening 166. Alternatively, for example, it may be specified that the support mechanism 156 is engaged into or passes through the through opening 166.

[0097] Advantageously, a sealing mechanism 182 may exist between the first zone 134 and the second zone 136. For example, the sealing mechanism 182 seals between the carrying mechanism 156 and the edge 180 of the through opening 166. Figure 2 The sealing mechanism 182 is schematically shown in the figure.

[0098] Especially in Figures 3 to 5 As can be seen from the diagram, the support mechanism 150 in this embodiment includes a support mechanism housing 184 (hereinafter: housing 184), which is located in... Figure 4 and Figure 5 The interior is shown open. The housing 184 is secured to the upper side of the support mechanism 156.

[0099] The housing 184 includes a plate-shaped housing component 186 forming the bottom of the housing 184, and other housing components 188 that are cover-shaped in this example. The housing component 188 covers the housing component 186. Figure 3 ) and together with housing component 186 surround receiving space 190 (in Figure 4 and Figure 5 (It is shown as open).

[0100] In addition, the housing 184 includes end walls 192, 194 at opposite ends.

[0101] The sealing mechanism 196 seals the housing 184, currently sealing between the end walls 192, 194 and the housing component 188. Thus, the housing 184 is sealed and isolated, particularly in a pharmaceutically suitable manner, allowing it to be cleaned by spraying or rinsing. The housing 184 can withstand VHP cycles, especially using H2O2.

[0102] The connecting element 168 passes through the housing component 186 and engages in the receiving space 190. Currently, the connecting element 168 can rotate about the rotation axis 198. A rotatable support is present at the bearing mechanism 154.

[0103] In particular, it is advantageous that there is no translational movement of the connecting element 168. The driving force of the drive motor 164 is transmitted to the retainer 160 only via rotational movement. By avoiding translational movement, especially between the first zone 134 and the second zone 136, the risk of particle entrainment is reduced, thereby ensuring a high level of hygiene for the operating device 120.

[0104] exist Figure 2 This type of configuration of the bearing mechanism 156 and the connecting element 168 is schematically shown in the figure.

[0105] In various embodiments, within the scope of the invention, it is conceivable that the connecting element 168 may undergo translational movement. For this purpose, the carrier 200 may be displaced relative to the carrier mechanism 156, within which the connecting element 168 may be displaced about a rotation axis 198. Figures 3 to 5 Rotation. The sealing mechanism 202 acts between the carrier 200 and the carrier mechanism 156 to seal and isolate the axial movement of the carrier 200.

[0106] However, it can be specifically stipulated that this type of translational movement is not performed while the equipment 100 is running, but only during preparatory measures, such as maintenance and / or refurbishment work. This is conceivable, for example, when specifications change.

[0107] In contrast, during operation of the device 100, the carrier 200 is preferably immovable relative to the carrier mechanism 156 to prevent particles, especially contaminant particles, from being entrained into the first zone 134. Only the rotationally driven connecting element 168 is used to drive the movement of the retainer 160 during operation. The rotational movement is sealed off via the sealing mechanism 202. This significantly improves hygienic properties.

[0108] exist Figure 3 The diagram schematically illustrates a drive unit 204 for the carrier 200. The drive unit 204 may be, for example, a spindle driver. Preferably, the two carriers 200 on either side of the operating system 118 can be driven together by a single drive unit 204.

[0109] Currently, the articulated arm 176 includes a first articulated arm section 206 rotatable relative to the support mechanism 150 and a second articulated arm section 208 rotatable relative to the first articulated arm section 206. The second articulated arm section 208 is rotatable relative to the retainer 160.

[0110] Currently, the first articulated arm segment 206 is shorter than the second articulated arm segment 208. The length ratio is approximately 1:2 to 1:3.

[0111] To enable rotation of the articulated arm section 206, the operating device 120 includes a drive element 210 at the corresponding support mechanism 150. Currently, the corresponding drive element 210 is designed as a shaft, which is partially arranged in the receiving space 190 and guided through a through opening 212 in the housing 184. For this purpose, the through opening 212 is formed in the end wall 192.

[0112] It should be understood that the drive elements 210 are designed to be symmetrical with respect to each other and to have the same function.

[0113] Bearing mechanisms 214 and 216 provide support for the drive element 210 to rotate about the (first) rotation axis 218. Bearing mechanisms 214 and 216 are arranged at end walls 192 and 194.

[0114] The drive element 210 is sealed and isolated relative to the end wall 192 of the housing 184 via a sealing mechanism 220. The sealing mechanism 220 is used for rotational sealing isolation using a rotating sealing element, such as a dual scraper.

[0115] The drive element 210 is currently connected to the connecting element 168 via a conical wheel 222 at the connecting element 168 or a conical wheel 224 at the drive element 210, the conical wheels 222 and 224 meshing with each other. The drive element is rotated about a rotation axis 218 by the rotation of the connecting element 168, the rotation axis 218 being oriented perpendicular to the rotation axis 198.

[0116] The drive element 210 is connected to the first articulated arm section 206 constituting the eccentric wheel in a manner without relative rotation.

[0117] The force transmission element 226, which is spaced from the drive element 210, is also connected to the first articulated arm section 206 in a manner without relative rotation. It defines a (second) axis of rotation 228, which is spaced from and oriented parallel to the first axis of rotation 218.

[0118] The force transmission element 226 is rotatably supported at the second articulated arm section 208. For this purpose, a bearing mechanism is arranged in the receiving opening 230 of the articulated arm section 208. A sealing mechanism 234 seals between the force transmission element 226 and the articulated arm section 208, currently in the form of a rotary seal with a rotating sealing element, such as a double scraper.

[0119] The receiving opening 230 is currently a through opening, which is closed by a cover element 236 on the side opposite to the articulated arm section 206.

[0120] In this example, the second articulated arm segment 208 includes additional receiving openings 238 designed as through openings. A force-transmitting element 240, currently designed as a shaft 242, engages in the receiving opening 238. The shaft 242 is guided through the through opening 244 of the retainer 160 in a manner without relative rotation.

[0121] In the articulated arm section 208, the shaft 242 is rotatably supported via a bearing mechanism 246. The sealing mechanism 248 seals the rotational movement and is designed as a rotating sealing element, such as a dual scraper. Figure 3 On the side opposite to the retainer 160, the receiving opening 238 is closed by means of the covering element 250.

[0122] The (third) rotation axis 252 defined by axis 242 is arranged in a spaced manner from and parallel to rotation axes 218 and 228.

[0123] In this example, the retainer 160 is designed as a plate. The plane of the retainer 160 is oriented laterally and, in particular, perpendicular to the axes of rotation 218, 228, and 252.

[0124] The guiding mechanism 154 includes a guide body 254. Currently, the guide body 254 is constructed as a column and is oriented laterally and particularly perpendicularly to the plane of the separating element 132. For example, the guide body 254 is secured to the separating element 132.

[0125] A slatted guide section 256 is formed at the guide body 254. Currently, the guide section 256 has at least one flat guide surface 258 extending along the direction of movement of the retainer 160. Currently, there are two guide surfaces 258 arranged on opposite sides of the guide section 256.

[0126] According to the invention, at least one guide element 260 is arranged at the guide body 254 to guide the retainer 160. Currently, multiple guide elements 260 are present, for example, three, but the invention is not limited thereto.

[0127] The guide element 260 is designed as a roller 262. The first roller 262 is rotatably supported on the shaft 242. For this purpose, the roller 262 has a bearing mechanism. In addition, a sealed isolation for rotation relative to the shaft 242 is provided by means of a sealing element.

[0128] When the roller 262 held at shaft 242 is arranged on one side of guide section 256, two other rollers 262 are currently arranged on the opposite side of guide section 256, away from roller 262. These two rollers 262 are spaced apart from each other along the direction of movement of retainer 160, which is defined by the extension direction of guide 254. The aforementioned roller at shaft 242 is arranged along the direction of movement between the two rollers 262 on opposite sides. Figure 4 ).

[0129] The two rollers mentioned later are rotatably mounted at the fixing element 264, which is held at the retainer 160 without relative rotation. Furthermore, a corresponding sealing mechanism exists for the fixing element 264 by means of a rotating sealing element.

[0130] A rolling surface 266 is arranged circumferentially at roller 262, and roller 262 rolls on a corresponding guide surface 258 formed in guide section 256 and facing the corresponding roller 262 via this rolling surface. This achieves particularly reliable guidance of the retainer 160.

[0131] The retainer 160, roller 262, and guide 254 are not enclosed. This allows these components to be cleaned, for example, by rinsing or spraying, during the cleaning of the operating device 120. Furthermore, the components can be purified, for example, by a VHP cycle using H2O2.

[0132] To avoid wear at the guide 254 and the roller 262 during operation of the operating device, the roller 262 is made of a wear-resistant material, preferably suitable for pharmaceutical use, at least in the area of ​​the rolling surface 266 and the guide 254 is made of a material, especially stainless steel, at least in the area of ​​the guide section 256.

[0133] As the connecting element 168 rotates, the driving element 210 rotates about the rotation axis 218. Correspondingly, this applies to the eccentric wheel formed by the first articulated arm section 206, which in turn rotates relative to the second articulated arm section 208 about the second rotation axis 228. The second articulated arm section 208 rotates relative to the retainer 160 about the third rotation axis 252.

[0134] This allows the retaining body 160 to move, with the movement occurring along the guide body 254. This is linear motion. In this example, it is specifically up-and-down motion.

[0135] This type of movement is performed by two retainers 160, wherein the movement is synchronized with each other via a transmission mechanism.

[0136] In order to operate the sealing element 114, the operating device 120 includes a tool 268. The tool 268 currently has a support member 270, which is preferably detachably secured to the two retainers 160 and connects the two retainers 160 to each other.

[0137] Furthermore, tool 268 has a retaining member 272, which is preferably detachably secured to the supporting member 270. At least one pushing element 274 for sealing element 114 is held in the retaining member 272. The pushing element 274 is designed as a push rod.

[0138] There are currently multiple actuating elements 274, which are fixed to the retaining member 272 at equal intervals. The retaining member 272 may be constructed together with the actuating elements 274 as a container-specific standardized component. Alternatively, for example, only the actuating elements 274 may be standardized components that are detachably fixed to the retaining member 272.

[0139] With the aid of the drive motor 164, the push element 274 can be moved translationally via the guided retainer 160. In particular, the push element 274 can be lowered and raised again in this case. The range of motion of the push element 274 is defined by the structure of the hinge mechanism 152 and its points of action at the support mechanism 150 and the retainer 160.

[0140] When the support mechanism 150 can be displaced relative to the support mechanism 156 via the carrier 200 through the drive unit 204, the height at which the push element 274 can be lowered and raised relative to it can be adjusted.

[0141] When the operating system 118 is running, the sealing element 114 is supplied by the storage device 124, which may in particular have a supply track 276 for this purpose. Figure 6 The storage device 124 upstream of the supply track 276 includes, for example, a container for sealing element 114, which is in the form of a transport tank.

[0142] The number of supply tracks 276 preferably corresponds to the number of pushing elements 274 and the number of receiving parts 278 of the receiving body 280 of the supply device 126.

[0143] Sealing element 114 is transported from supply track 276 to receiving section 278. Figure 6 (Not shown in detail).

[0144] The supply device 126 will receive the body 280 from Figure 6 The receiving position shown moves to Figure 7 and Figure 8 The handover location is shown.

[0145] In the handover position, the sealing element 114 is positioned above the container 102, which is positioned on the placement element 144. The sealing element 114 is aligned with respect to the container 102.

[0146] During this conveying of the sealing element 114, the pushing element 274 takes a basic position ( Figure 7 In this basic position, the pushing element is positioned above the sealing element 114. Subsequently, the pushing element 274 moves towards the sealing element 114 into the pressing position. Figure 8 (in order to apply force to the sealing element 114 in the direction of container 102).

[0147] The guided movement of the pushing element 274 occurs here along the container axis 146, which is parallel to the extending orientation of the guide 254. The sealing element 114 is pressed from the receiving portion 278 against the container 102 by the pushing element 274 to seal it.

[0148] Sensor mechanism 282 can be set ( Figure 2 The sensor mechanism can be connected to the control device 148, and the operating device 118 can be monitored via the sensor mechanism. In the event of a malfunction, the operating device 118 can stop operating.

[0149] The sensor mechanism 282 is designed, for example, optically and currently includes a photoelectric sensor (e.g., using a laser) with transmitting and receiving elements 284 and a reflector 286. The transmitting and receiving elements 284 are, for example, secured in a frame 128, and the reflector 286 is secured in a holder 160 or a support member 270. Reference numeral 288 denotes an optical path.

[0150] Mechanical overload protection is provided for each actuating element 274, and it is currently arranged in the holding member 272. In the event of overload due to pressing force, the corresponding actuating element 274 disengages. This can be determined by the interruption of the optical path 288 via the sensor mechanism 282.

[0151] Explanation of reference numerals in the attached figures

[0152] 100 devices

[0153] 102 containers

[0154] 104 tubular bottle

[0155] 106 Processing Station

[0156] 108 Weighing Station

[0157] 110 Filling Station

[0158] 112 Sealing Station

[0159] 114 sealing element

[0160] 116 Production Materials

[0161] 118 Operating System

[0162] 120 operating device

[0163] 122 Sealing Device

[0164] 124 storage devices

[0165] 126 supply unit

[0166] 128 frame

[0167] 130 resettlement areas

[0168] 132 dividing element

[0169] 134 First District

[0170] 136 Second District

[0171] 138 Lower Structure

[0172] 140 Machine Protective Equipment

[0173] 142 Conveyor System

[0174] 144 mounting elements

[0175] 146 Container Axis

[0176] 148 control device

[0177] 150 support institutions

[0178] 152 articulated mechanism

[0179] 154 Guiding Organization

[0180] 156 bearing mechanism

[0181] 158 drive mechanism

[0182] 160 maintain body

[0183] 162 Central Plane

[0184] 164 drive motors

[0185] 166 through opening

[0186] 168 connecting elements

[0187] 170 transmission mechanism

[0188] 172 drive belt

[0189] 174 driving components

[0190] 176 articulated arm

[0191] 178 casing

[0192] 180 edge

[0193] 182 Sealing Mechanism

[0194] 184 Support Mechanism Housing

[0195] 186, 188 housing components

[0196] 190 Acceptance Space

[0197] 192, 194 end wall

[0198] 196 Sealing Mechanism

[0199] 198 Rotation axis

[0200] 200 load-bearing bodies

[0201] 202 Sealing Mechanism

[0202] 204 drive unit

[0203] 206 First articulated arm section

[0204] 208 Second articulated arm section

[0205] 210 drive element

[0206] 212 through opening

[0207] 214 and 216 bearing mechanisms

[0208] 218 First Rotation Axis

[0209] 220 sealing mechanism

[0210] 222 and 224 conical wheels

[0211] 226 Force Transmission Components

[0212] 228 Second Rotation Axis

[0213] 230 receiving opening

[0214] 232 bearing mechanism

[0215] 234 Sealing Mechanism

[0216] 236 Covering Components

[0217] 238 Reception Opening

[0218] 240 force transmission element

[0219] 242 shafts

[0220] 244 through opening

[0221] 246 bearing mechanism

[0222] 248 Sealing Mechanism

[0223] 250 Covering Components

[0224] 252 Third Rotation Axis

[0225] 254 guide body

[0226] 256 Guide Section

[0227] 258 guide surfaces

[0228] 260 boot element

[0229] 262 rollers

[0230] 264 Fixing Components

[0231] 266 rolling surface

[0232] 268 Tools

[0233] 270 load-bearing components

[0234] 272 retaining components

[0235] 274 driving element

[0236] 276 supply track

[0237] 278 accepted

[0238] 280 Recipients

[0239] 282 sensor mechanism

[0240] 284 Transmitting and Receiving Elements

[0241] 286 reflector

[0242] 288 optical paths

Claims

1. An operating device (120) for pharmaceutical production materials (116), comprising The support mechanism (150), the articulation mechanism (152) including a first articulated arm section (206) and a second articulated arm section (208), at least one drive mechanism (158), and a tool (268) for acting directly or indirectly on the production material (116). The operating device (120) includes a drive element (210) drivable about a first rotation axis (218), the drive element being connected to the first articulated arm segment (206) in a non-relative rotational manner, wherein the first articulated arm segment (206) and the second articulated arm segment (208) are connected to each other in a manner drivable relative to each other about a second rotation axis (228), wherein the rotation axes (218, 228) are arranged with a distance between them. The operating device (120) includes a guide mechanism (154) and a retainer (160), the guide mechanism having a guide body (254), the retainer including or constituting the tool (268), or the tool (268) being held at the retainer, wherein the second articulated arm segment (208) is rotatable relative to the retainer (160) about a third rotation axis (252), the third rotation axis being arranged in a spaced manner from the second rotation axis (228), and at least one guide element (260) cooperating with the guide body (254) is arranged at the retainer (160).

2. The operating device (120) according to claim 1. Its features are, The operating device (120) does not have a drive motor for the articulated arm sections (206, 208) at the articulation mechanism (152) and / or at the support mechanism (150), and / or the operating device (120) does not have an auxiliary pipeline for the drive motor at the articulation mechanism (152) and / or at the support mechanism (150).

3. The operating device (120) according to claim 1 or 2. Its features are, The guide (254) is configured to extend in a straight line, and in particular, to be a rod or slat.

4. The operating device (120) according to any one of the preceding claims. Its features are, The guide (254) has a flat guide surface (258) for at least one of the guide elements (260).

5. The operating device (120) according to any one of the preceding claims. Its features are, At least one of the following applies: - At least one of the guide elements (260) is a roller (262), preferably made of a metallic material, especially stainless steel; - Provide two or more guide elements (260), wherein two guide elements (260) are arranged on the side of the guide (254) away from each other.

6. The operating device (120) according to any one of the preceding claims. Its features are, The guide (254) and the retainer (160), together with at least one guide element (260) disposed thereon, are not covered by the housing.

7. The operating device (120) according to any one of the preceding claims. Its features are, The articulated arm sections (206, 208) are configured to have different lengths, and in particular, the first articulated arm section (206) is shorter than the second articulated arm section (208).

8. The operating device (120) according to any one of the preceding claims. Its features are, The support mechanism (150) includes or constitutes a support mechanism housing (184), and the drive element (210) is partially arranged in the support mechanism housing, wherein the drive element (210) is guided through at least one through opening (166, 212, 244) of the support mechanism housing (184), preferably, the drive element (210) is rotationally sealed relative to the support mechanism housing (184).

9. The operating device (120) according to claim 8. Its features are, The operating device (120) includes a coupling element (168) associated with the drive element (210), the coupling element being drivable by at least one of the drive mechanisms (158), wherein the coupling element (168) engages in the support housing (184) and is coupled therein to the drive element (210).

10. The operating device (120) according to any one of the preceding claims. Its features are, The connecting element (168) is connected to the driving element (210) via an engagement portion, particularly via interlocking conical wheels (222, 224).

11. The operating device (120) according to any one of the preceding claims. Its features are, The tool (268) includes at least one pusher (274) for acting on a sealing element (114), particularly for sealing a medical container (102).

12. The operating device (120) according to claim 11. Its features are, The tool (268) is configured as a multi-point device and in particular includes a plurality of actuating elements (274).

13. The operating device (120) according to any one of the preceding claims. Its features are, The guiding mechanism (154) includes two guide bodies (254), two support mechanisms (150), two drive elements (210), two hinge mechanisms (152) each having two hinge arm sections (206, 208), and two retainers (160) and guide elements (260) arranged thereon, wherein the tool (268) is held in the two retainers (160), or the two retainers (160) include or constitute the tool (268). In particular, the operating device (120) includes two connecting elements (168) connected to the corresponding drive elements (210).

14. The operating device (120) according to claim 13. Its features are, At least one of the drive mechanisms (158) includes a drive motor (164) for driving the two drive elements (210), particularly indirectly via two connecting elements (168), wherein the drive mechanism (158) preferably includes or constitutes a drive belt connected to the two connecting elements (168) in a manner without relative rotation.

15. The operating device (120) according to claim 13, Its features are, At least one of the drive mechanisms (158) includes two separate drive motors (164) associated with corresponding coupling elements (168), wherein the drive motors (164) are preferably synchronized with each other.

16. An operating system (118) for pharmaceutical manufacturing materials (116), comprising: A frame (128) that can be mounted on a mounting surface (130) and includes, in particular, a plate-shaped partition element (132) that separates a first zone (134) from a second zone (136), wherein the first zone (134) has a higher cleanliness level than the second zone (136); an operating device (120) according to any of the preceding claims, wherein the support mechanism (150) and the hinge mechanism (152) are arranged in the first zone (134), wherein at least one of the drive mechanisms (158) is arranged in the second zone (136), wherein at least one connecting element (168) of the operating device (120) is guided through at least one through opening (166, 212, 244) of the partition element (132).

17. The operating system (118) according to claim 16. Its features are, The operating system (118) includes, in particular, a cylindrical support mechanism (156) in which at least one of the connecting elements (168) is arranged, and the support mechanism passes through or engages with the through opening (166, 212, 244) or abuts against the edge (180) of the through opening (166, 212, 244) in the first region (134); and preferably includes sealing mechanisms (182, 196, 202, 220, 234, 248) for sealing and isolating the through opening (166, 212, 244) between the first region (134) and the second region (136).

18. The operating system (118) according to claim 17. Its features are, At least one of the connecting elements (168) or the supporting mechanism (156) does not have linear movement, especially lifting movement, through the through openings (166, 212, 244).

19. The operating system (118) according to any one of claims 16 to 18. Its features are, The operating system (118) includes at least one conveying track for a sealing element (114) and a holding element for a container (102) to be sealed, wherein the tool (268) is movable from a basic position, particularly in a linear manner, to a pressing position and vice versa, wherein the pushing element (274) has a larger distance from the sealing element (114) in the basic position than in the pressing position, and wherein the sealing element (114) in the pressing position can be subjected to a force pointing toward the container (102).

20. An apparatus (100) for processing a medical container (102), comprising an operating system (118) according to any one of claims 16 to 19, wherein the operating system (118) includes or constitutes a sealing station (112) for the container (102), and wherein at least one other processing station (106), such as a filling station (110), is provided for the container (102).

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