An opicapone orally disintegrating tablet and a method of preparing the same

By preparing octopcapone orally disintegrating tablets, the problem of difficulty in swallowing was solved, achieving rapid disintegration and administration without water, thus improving patient compliance and production applicability.

CN122398740APending Publication Date: 2026-07-17SEASONS BIOTECHNOLOGY (TAIZHOU) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SEASONS BIOTECHNOLOGY (TAIZHOU) CO LTD
Filing Date
2025-01-15
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing octopaine capsules and regular tablets are difficult to swallow, especially for the elderly and patients with digestive tract diseases, and cannot meet the patient's medication compliance needs.

Method used

We developed octopcapone orally disintegrating tablets containing specific proportions of octopcapone, fillers, glidants, lubricants, and various disintegrants. We employed a dry granulation process to ensure that the tablet hardness and disintegration time met the requirements.

Benefits of technology

It achieves rapid disintegration of octopaine orally disintegrating tablets without the need for water, improving patient compliance and comfort, and is suitable for industrial production.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application belongs to the technical field of medicine, and particularly relates to a kind of opicapone oral disintegrating tablets and a preparation method thereof.The active component of the opicapone oral disintegrating tablet is opicapone, and the components are as follows according to weight percentage: opicapone 15-25%; filler 60-70%; glidant 1-4%; lubricant 1-4%; first disintegrating agent 2-6%; and second disintegrating agent 2-6%, wherein the first disintegrating agent and the second disintegrating agent are different, and preferably, the weight content of the opicapone is 15-20%.The opicapone oral disintegrating tablet of the application is suitable for the adjuvant therapy of levodopa / carbidopa, has a fast disintegration rate, stable product quality, does not need to be taken with water, and has strong patient compliance; in addition, the preparation process of the opicapone oral disintegrating tablet of the application is simple, has low cost, and is suitable for mass production.
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