A medicinal and edible homologous traditional Chinese medicine composition for protecting liver from alcohol and its preparation method and application

By combining a specific ratio of medicinal and edible herbs such as turmeric, kudzu root, astragalus, gardenia, hawthorn, poria, wolfberry, licorice, and chicken gizzard lining, a hangover remedy and liver-protecting agent is prepared. This solves the problems of large side effects and high cost in existing technologies, achieving a safe and effective hangover remedy and liver-protecting effect, restoring the activity of alcohol-metabolizing enzymes, inhibiting oxidative stress and inflammation, and protecting liver cells.

CN122398973APending Publication Date: 2026-07-17ZUNYI INST OF AGRI SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZUNYI INST OF AGRI SCI
Filing Date
2026-04-14
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing traditional Chinese medicine compositions for relieving hangovers and protecting the liver use a large number of non-food and medicine herbs, resulting in significant side effects and high production costs. It is difficult to find safe, effective, and low-cost traditional Chinese medicine compound formulas that are both food and medicine to treat alcoholic liver disease using current technology.

Method used

Using medicinal and edible herbs such as turmeric, kudzu root, astragalus, gardenia, hawthorn, poria, wolfberry, licorice, and chicken gizzard lining, these herbs are combined in specific proportions to prepare powders, pills, or tablets for relieving hangovers and protecting the liver. By utilizing the dosage relationships of principal, assistant, adjuvant, and guiding herbs, the formula achieves the effects of detoxifying alcohol, protecting liver yin, and regulating qi and blood.

Benefits of technology

It restores the activity of key enzymes in alcohol metabolism, inhibits oxidative stress and lipid peroxidation, improves bile metabolism, inhibits the overexpression of inflammatory factors, protects hepatocyte membrane and mitochondrial function, significantly reduces hepatocyte damage markers, and improves pathological changes such as steatosis, inflammation and apoptosis. It has high safety and is suitable for widespread application.

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Abstract

本发明涉及中药组合物技术领域，尤其涉及一种用于解酒护肝的药食同源中药组合物及制备方法和应用，由姜黄、葛根、黄芪、栀子、山楂、茯苓、枸杞、甘草、鸡内金组成，经过恰当原料用量关系控制，达到了如下功效：①恢复关键酶 ADH 与 ALDH 的活性，从源头减少乙醛蓄积及毒性损伤；②降低 MDA、LDH 等标志物水平，阻断自由基链反应并维持细胞膜稳定性；③改善胆汁代谢功能，下调TBIL与γ‑GT水平，缓解胆汁淤积并减少胆管炎性损伤；④抑制炎症因子过度表达，有效降低 IL‑1β、TNF‑α、IL‑6等促炎因子水平，阻断炎性信号放大与免疫攻击对肝组织的进一步破坏；⑤保护肝细胞膜与线粒体功能，显著降低 ALT、AST 等肝细胞损伤标志物，改善脂肪变性、炎症与凋亡等病理改变。
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Citation Information

Patent Citations

  • Traditional Chinese medicine composition for dispelling effects of alcohol as well as preparation method and application of traditional Chinese medicine composition

    CN115737755A

  • Compound anti-alcohol traditional Chinese medicine composition and preparation method thereof

    CN115737777A

  • A traditional Chinese medicine composition for relieving hangovers and protecting the liver, and its preparation method.

    CN115845011B

  • Composition for dispelling effects of alcohol and protecting liver and application thereof

    CN120305376A