A method and system for analyzing a blood vessel network of a moyamoya disease and simulating a bypass surgery based on multi-modal images

By using spatial geometric alignment, feature fusion and verification reconstruction, parametric analysis and physical constraint prediction of multimodal image data, the problems of fragmentation and artifacts in the vascular network model of Moyamoya disease were solved, and efficient, real-time simulation and quantitative screening of surgical targets for Moyamoya disease vascular network were achieved.

CN122417434APending Publication Date: 2026-07-17TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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Patent Information

Application Number
CN202610451896.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-08
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing vascular analysis and simulation technologies struggle to balance suppressing background noise and preserving realistic vascular details when dealing with moyamoya disease. This results in vascular network models that are prone to breakage or contain artifacts. Furthermore, traditional methods are computationally intensive and time-consuming, making it difficult to achieve real-time assessment during the surgical planning stage.

Method used

By using spatial geometric alignment, feature fusion and verification reconstruction, parametric analysis and physical constraint prediction of multimodal image data, the topology of the vascular network in Moyamoya disease is reconstructed. Blood perfusion distribution is predicted using neural network and computational fluid dynamics simulation data, and surgical targets are screened by combining a multidimensional quantitative evaluation mechanism.

Benefits of technology

It significantly improves the topological reconstruction of the microvascular network in Moyamoya disease, provides objective quantitative surgical target reference, and enables real-time simulation and comparison of blood perfusion effects within seconds, avoiding high-risk anastomosis areas.

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Abstract

本发明涉及医学影像处理与计算机辅助外科手术技术领域,公开了一种基于多模态影像的烟雾病血管网络分析与搭桥手术模拟方法及系统。本发明旨在解决现有技术中烟雾病微血管重建精度低、手术靶点筛选缺乏客观量化标准以及术后血流模拟计算效率不足的技术问题。本发明通过以CT数据为刚性基准实现多模态影像的空间几何对齐;利用融合二维纹理与三维拓扑特征的双通道神经网络架构,并结合原始信号强度校验逻辑重构微血管拓扑结构;基于血管几何参数、钙化程度及皮层深度指标建立多维量化评价机制以筛选手术靶点;利用受质量守恒定律约束的条件生成对抗网络进行血流预测。
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