Infectious disease monitoring and early warning method and system based on large language model and knowledge graph

By combining large language models with knowledge graphs, a port spatiotemporal knowledge graph is constructed and a metapopulation graph transformation neural network is used to solve the problems of heterogeneity and dynamic modeling of multi-source data, realize efficient infectious disease monitoring and early warning, and provide accurate risk assessment and intervention strategies.

CN122417461APending Publication Date: 2026-07-17SHANDONG UNIV
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Patent Information

Application Number
CN202610864371.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-06-16
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing infectious disease monitoring and early warning systems struggle to effectively integrate multi-source heterogeneous data in port scenarios, lack the ability to dynamically model cross-regional, cross-species, and cross-modal transmission risks, and are prone to misjudging or missing transmission signals. They also lack the ability to adaptively characterize the dynamic relationships between population movement, animal habitats, and logistics routes.

Method used

By combining a large language model with a knowledge graph, cross-modal feature alignment is achieved through a dynamic time lag masking mechanism, and a spatiotemporal knowledge graph covering people, animals, goods, and the environment is constructed. A meta-population graph transformation neural network is used for forward graph convolutional propagation, and a multi-agent cluster is activated to perform counterfactual inference to generate structured disposal instructions.

Benefits of technology

It has achieved efficient fusion and feature alignment of multi-source data, improved the ability to quickly trace the transmission path of infectious diseases and assess risks, enhanced the timeliness and accuracy of early warning, and provided support for scientific intervention strategies.

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Abstract

本发明公开了一种基于大语言模型与知识图谱的传染病监测预警方法及系统,属于公共卫生监测与人工智能技术领域。方法包括:获取口岸的泛在感知数据;构建融合流行病学潜伏期先验知识的动态时间滞后掩码矩阵,并基于所述矩阵对泛在感知数据进行跨模态特征对齐;基于对齐后的跨模态特征,实例化异构实体构建具有双边时空拓扑约束的网络边,生成口岸时空知识图谱;利用元种群图变换神经网络在时空知识图谱中推算时变传染病动力学参数并评估扩散风险;当风险超过预设的动态阈值域时,激活大语言模型多智能体集群,执行反事实推演并自动化生成处置指令。本发明有效解决了多源异构数据难以联动分析、传播时序错位及隐性风险难以追溯的问题。
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