CONNECTION FOR USE IN RETINAL DISEASES

DE602019085487T2Active Publication Date: 2026-06-03ZHUHAI UNITED LAB
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Patent Information

Application Number
DE602019085487
Authority / Receiving Office
DE · DE
Patent Type
Patents
Current Assignee / Owner
Priority Date
2019-12-04
Filing Date
2019-12-18
Publication Date
2026-06-03
Estimated Expiration
2039-12-18

AI Technical Summary

Technical Problem

Xerophthalmia, characterized by decreased tear film stability due to abnormal tear quality or quantity, leads to eye discomfort and ocular surface inflammation, often triggered by aldehydes like malondialdehyde and 4-hydroxy-2-nonenal, which react with proteins and DNA, causing tissue damage.

Method used

A compound represented by formula (I) or its pharmaceutically acceptable salt, which binds to aldehydes in vivo through complexation, reducing aldehyde toxicity and inflammation.

Benefits of technology

The compound effectively reduces aldehyde-induced inflammation, thereby treating xerophthalmia by stabilizing the tear film and alleviating eye discomfort.

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