Transferrin receptor binding molecules, their conjugates, and their use for the prevention or treatment of neurological disorders.

JP2026521070APending Publication Date: 2026-06-25VECTOR-ALL +2
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
VECTOR-ALL
Filing Date
2024-06-21
Publication Date
2026-06-25

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Abstract

The present invention relates to variable domains (VHHs) of camelid heavy chain molecules that bind to TfR, conjugate compounds containing such VHH molecules, and their use for, for example, transporting molecules for pharmaceutical purposes to cells and organs in pathological conditions in the CNS or PNS, including cancer.
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Citation Information

Patent Citations

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    WO2010046588A1

  • Peptide derivatives, preparation thereof and uses thereof

    WO2011131896A2

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    WO2012075037A1

  • Methods for improving safety of blood-brain barrier transport

    WO2013177062A2

  • TfR SELECTIVE BINDING COMPOUNDS AND RELATED METHODS

    WO2016077840A2