Sample analysis cartridge and method for manufacturing the same

JP7873983B2Active Publication Date: 2026-06-15SYSMEX CORP +2

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
SYSMEX CORP
Filing Date
2022-04-08
Publication Date
2026-06-15

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Abstract

To provide a specimen analysis cartridge and the like with increased liquid leakage durability.SOLUTION: A specimen analysis cartridge includes a first substrate having a microfluidic channel formed on at least one surface thereof, a second substrate arranged opposite the surface on which the microfluidic channel is formed on the first substrate, and a photocurable resin layer by which the first substrate and the second substrate are bonded together. The first and second substrates include at least one of a cyclo-olefin polymer and a cyclo-olefin copolymer.SELECTED DRAWING: Figure 1
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Claims

1. A first substrate having microchannels formed on at least one side, A second substrate is disposed opposite to the surface of the first substrate on which the microchannels are formed, The invention comprises a photocurable resin layer that adheres the first substrate and the second substrate, The first substrate and the second substrate each contain at least one of a cycloolefin polymer and a cycloolefin copolymer. The 180° peel strength between the first substrate and the second substrate is 20 N / 10 mm or more. Sample analysis cartridge.

2. The sample analysis cartridge according to claim 1, wherein the thickness of the photocurable resin layer is 1.0 μm or more and 100 μm or less.

3. The sample analysis cartridge according to claim 1, wherein the minimum channel width of the microchannel is 200 μm or less.

4. The sample analysis cartridge according to claim 1, wherein the 180° peel strength between the first substrate and the second substrate is 25 N / 10 mm or more.

5. The sample analysis cartridge according to claim 1, wherein the photocurable resin layer comprises an acrylic resin and / or a methacrylic resin.

6. The sample analysis cartridge according to claim 1, wherein the photocurable resin layer is a cured product of a photocurable resin composition comprising (a) an acrylic oligomer and / or methacrylic oligomer with a weight-average molecular weight of 2000 or more, (b) an acrylic monomer and / or methacrylic monomer, and (c) a photoradical polymerization initiator.

7. The sample analysis cartridge according to claim 6, wherein the (a) acrylic oligomer and / or methacrylic oligomer has a polyurethane skeleton.

8. A method for manufacturing a sample analysis cartridge according to any one of claims 1 to 7, The aforementioned manufacturing method is The process involves applying a photocurable resin composition to the first substrate using an inkjet method, A step of bonding the second substrate to the surface of the first substrate to which the photocurable resin composition has been applied, A manufacturing method comprising the step of irradiating the photocurable resin composition with light to form the photocurable resin layer.

9. The manufacturing method according to claim 8, wherein the viscosity of the photocurable resin composition is 1.0 mPa·s or more and less than 50 mPa·s.