Adipocytolytic composition and cosmetic method for localized fat reduction

The use of a conjugated compound of cholecalciferol polyethylene glycol succinate (CPGS) addresses the safety concerns of existing injectable lipolytic agents by providing controlled adipocyte lysis for localized fat reduction with minimal side effects.

WO2026115475A1PCT designated stage Publication Date: 2026-06-04VIDA AB
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
VIDA AB
Filing Date
2025-11-27
Publication Date
2026-06-04

AI Technical Summary

Technical Problem

Existing injectable lipolytic agents for fat reduction, such as bile acids and their derivatives, are non-selective and cause significant side effects, including inflammation and toxicity, necessitating a need for compounds that are effective and safe with controlled action.

Method used

A composition comprising a conjugated compound of a cyclic or polycyclic hexyl secondary alcohol and a polyether organic polymer, optionally linked by a hydrocarbon chain, specifically cholecalciferol polyethylene glycol succinate (CPGS), is used for targeted adipocyte lysis with minimal side effects.

Benefits of technology

The composition achieves localized fat reduction with controlled adipocyte lysis, enhancing aesthetic appearance and maintaining body contour while minimizing side effects.

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Abstract

Cosmetic composition comprising a conjugated compound consisting of a hexyl secondary alcohol, a polyether organic polymer and, optionally, a C2-C22 hydrocarbon chain, saturated or unsaturated, cis or trans, linear or branched, with at least two carboxyl groups and its use for removing subcutaneous fat deposits.
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Citation Information

Patent Citations

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    CN110327278A

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    EP3124080A1

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    EP4091602A1

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    US20160089384A1