Preparation method for synthesizing methyl benzoylformate by virtue of one-pot method

The production process of methyl acetophenonate is simplified through a one-pot reaction, which solves the problems of complex processes and environmental pollution in the existing technology, achieves efficient and environmentally friendly synthesis of methyl acetophenolate, and reduces equipment and operating costs. .

CN103408424AInactive Publication Date: 2013-11-27HEBEI CHENGXIN
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Patent Information

Application Number
CN201310371636.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2013-08-22
Publication Date
2013-11-27
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In the existing technology, the production process of methyl acetophenolate is complex, the use of potassium permanganate causes environmental pollution, and the process flow is long, which increases equipment and operating costs.

Method used

A one-pot method is used to react benzoyl nitrile, alcohol, catalyst and concentrated sulfuric acid at a specific ratio and temperature. Methyl acetophenonate is synthesized through liquid separation and neutralization, which simplifies the process and reduces raw material consumption.

Benefits of technology

It shortens the reaction time, reduces the usage of raw materials, reduces production wastewater, and achieves a high-yield and environmentally friendly industrial process.

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Abstract

The invention relates to a preparation method for synthesizing methyl benzoylformate by virtue of a one-pot method. The method comprises the following steps of: mixing benzoyl cyanide, alcohol, a catalyst and water and dropwise adding concentrated sulfuric acid, and synthesizing methyl benzoylformate by adopting the one-pot method; then, performing post-treatment to split salt and neutralize acid ester to obtain a coarse product. According to the preparation method provided by the invention, the process flow can be simplified, the production energy consumption can be reduced, and the yield can be improved, so that the quantity of wastewater in production is greatly reduced, and wastewater can be used for producing ammonium sulfate. The preparation method is an environmentally-friendly process, and the whole process is very beneficial to industrial implementation.
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