Test apparatus for evaluating spatial orientation ability in humans or non-human primates
By designing a test device including support components, wall panel components and folding door components, the problem of lack of spatial navigation capability evaluation models for humans or non-human primates in the prior art is solved, and an effective evaluation of human spatial cognitive abilities is achieved, which is suitable for early diagnosis and efficacy evaluation of Alzheimer's disease.
Patent Information
- Application Number
- CN202010179142.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-03-16
- Publication Date
- 2025-04-29
- Estimated Expiration
- 2040-03-16
AI Technical Summary
The existing test devices for space navigation capability are mainly suitable for animals, and there is a lack of effective evaluation models and test devices for human or non-human primates, especially in the early diagnosis and evaluation of drug efficacy.
A test device including support components, wall panel components and folding door components is designed. The device tests the patient's spatial navigation ability through an evaluation method that increases difficulty step by step, and simulates complex scenarios to evaluate the human body's spatial cognitive ability through technical means such as unmanned trolleys and LED markings.
The device can effectively evaluate the spatial navigation capabilities of humans or non-human primates, provide reliable evaluation results, is suitable for the early diagnosis and efficacy evaluation of Alzheimer's disease, and is easy to use and low cost.
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Figure CN111357675B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to a maze experimental device, in particular to an experimental device for evaluating the spatial positioning ability of humans or non-human primates, which is mainly suitable for the diagnosis and evaluation of dementia, such as Alzheimer's disease. Background Art
[0002] As my country's population structure gradually ages, the number of people with Alzheimer's disease is also on the rise. Alzheimer's disease (AD) is a progressive neurodegenerative disease with an insidious onset. Healthy elderly people experience a decline in navigation ability with age, which manifests as normal social functions and daily life, but impaired spatial navigation ability in the cognitive field. This impairment is more significant in Alzheimer's disease (AD). AD is the most common cause of dementia in people over 60 years old, and its prevalence increases with age. Impairment of spatial navigation ability has a certain specificity in AD, and its impairment can be detected in the early clinical stage of AD, that is, mild cognitive impairment (MCI). Therefore, testing spatial navigation ability may be an indicator with high sensitivity and specificity for early diagnosis of AD in patients with MCI who are at high risk of AD conversion. In addition, "Spatial Navigation-A New Indicator for Early Diagnosis of Alzheimer's Disease", Chinese Journal of Practical Internal Medicine, 2015-02, 35(2) also discussed the main causes of AD.
[0003] In the prior art, human cognitive ability is mainly evaluated based on scores of scales such as ADAS-cog, ADCS-ADL, CIBIC, and NPI. The existing spatial navigation ability test equipment is mainly the Morris water maze. However, the existing test devices mainly use animals as test subjects, and there is still a lack of an evaluation model for human spatial recognition ability and a test device using the evaluation model. In the early stages of AD, when the atrophy of the hippocampus, frontal lobe, temporal lobe, and parietal lobe is not obvious, and the gyrus has not become significantly narrowed, it is difficult to diagnose the disease through brain CT. For the efficacy evaluation of AD therapeutic drugs, frequent brain CT observations of efficacy will increase medical expenses, which is difficult for ordinary families to afford. In drug clinical trials, it will also push up research and development costs.
[0004] Existing test devices, such as the invention patent application with application publication number CN101142900A, discloses a "method and device for enhancing spatial memory of animals in water maze experiments". The IPC classification number of this technical solution is A01K15 / 02, which specifically includes a water tank for animals to swim, a platform set in the water, a camera and a computer system, and a visual reference system: the visual reference system is to set a barrier above the outer periphery of the water tank to isolate external interference: the visual reference system also sets a plurality of fixed patterns that contrast with the color of the barrier on the inside of the barrier as memory references for animals. For example, the invention patent application with application publication number CN 102422818A discloses an "advanced fully automatic intelligent Morris water maze analysis system". The IPC classification number of this technical solution is A01K15 / 02, which specifically includes a water basin, a bracket for setting the water basin, and a uniform lighting system installed in the water basin, and the water basin is provided with a drain. The uniform lighting system includes a plurality of spotlights with the same brightness, and the light spots projected by the spotlights are evenly distributed around the water basin; it also includes an adapter interface for a mobile terminal and a desktop terminal, and the interface is used for the transmission of experimental data and control signals between the control box and multiple platforms and multiple terminals. A corresponding expansion system is also provided. The above schemes are all water mazes for animal experiments, and the existing human water mazes are mostly virtual water mazes with a single function, which cannot be used in complex scenes to evaluate the spatial cognitive ability of the human body. Summary of the invention
[0005] The purpose of the present invention is to provide a test device for evaluating the spatial positioning ability of humans or non-human primates, which fundamentally solves the above-mentioned problems and has the advantages of diverse functions, reliable and effective evaluation results, easy use, and low cost.
[0006] To achieve the above-mentioned purpose, the present invention provides the following technical solution: The test device for evaluating the spatial positioning ability of humans or non-human primates has the following technical features: it comprises a support component (1), a wall panel component (2), and a folding door component (3);
[0007] The support assembly (1) comprises a floor assembly (14), side columns (12) and a middle column (13) perpendicular to the floor assembly (14), and a guide rail assembly (11) supported on the ceiling; the floor assembly (14) comprises a base (143), a lifting motor (144) arranged in the base, a lifting plate (142) with one end movably limited in the base (143) and driven by the lifting motor (144), and a mesh plate (141); one end of the lifting plate (142) is connected to a corner portion (1422) via a bending portion (1421), and a sewage outlet (1431) is provided on the base on one side of the corner portion (1422);
[0008] The wall panel assembly (2) comprises a plurality of U-shaped trolley shells, running wheels (313) arranged between the trolley shells, and a strip-shaped wall panel arranged at the bottom of the trolley shells; the slide rail portion of the guide rail assembly (11) is located between the running wheels (313) and the trolley shells;
[0009] The folding door assembly (3) comprises a sliding trolley assembly (31), a telescopic column assembly (32), and a foldable door panel assembly (33);
[0010] The sliding trolley assembly (31) comprises a plurality of U-shaped trolley shells, running wheels (313) arranged between the trolley shells, a running motor arranged at the input end of the end running wheels (313), a trolley connection portion arranged at the bottom of the end trolley shell, a long connecting rod (315) and a short connecting rod (316) hinged between the trolley connection portion and the telescopic column assembly (32), a lifting motor (314) whose output end is located between the two connecting rods and whose fixed end is hinged to the bottom of the trolley shell, and a control circuit; each trolley shell is connected in series in sequence through a male hinge ear and a female hinge ear at both ends, and the slide rail portion of the guide rail assembly (11) is located between the running wheel (313) and the trolley shell;
[0011] The telescopic column assembly (32) comprises a plurality of coaxially arranged reducing sleeves, a lead screw and a driven gear arranged in the sleeves, a lifting motor reducer assembly (321) arranged at the input end of the driven gear, a hoop limited by a limiting boss at the bottom of each sleeve, and a universal wheel assembly (327) movably arranged at the bottom;
[0012] The foldable door panel assembly (33) comprises a plurality of hinged parts (333) fixed on each ring hoop, and a plurality of door panel assemblies (33) connected end to end in sequence and matched with telescopic column sleeves; the door panel assemblies (33) are connected in sequence through raised parts and embedded parts at both ends, and are rotatably connected to the hinged parts (333) through the raised parts, wherein one side of one or more door panel assemblies (33) is provided with an LED display module.
[0013] The beneficial effects of the present invention are as follows: the impairment of spatial navigation ability is related to the changes in its corresponding structure and circuit. The navigation process of normal people involves a wide range of brain area activities. From the perspective of the whole brain, the navigation network involves the occipital lobe, parietal lobe, temporal lobe and frontal lobe; from the perspective of specific brain structures, the precuneus, retrosplenial cortex, parietal cortex, parahippocampal gyrus and hippocampus have important functions. The navigation circuit includes surround reference navigation and self-reference navigation. Existing studies believe that environmental reference navigation and self-reference navigation have consistent decoding spatial information patterns, and it is difficult to completely separate the two reference navigations from a functional perspective. In the navigation process, a mixed reference navigation is more likely. Self-reference navigation obtains spatial information through the senses and decodes it in the parietal cortex. The spatial information obtained after decoding is transmitted to the hippocampus through the retrosplenial cortex for environmental reference decoding. The anterior part of the hippocampus is responsible for the formation of cognitive maps. The posterior part of the hippocampus is responsible for the formation of spatial memory and the storage of cognitive maps. Working memory is involved in the process of spatial memory formation. In addition, the frontal cortex is involved in executive functions such as route selection and flexible navigation. The caudate nucleus is activated in certain specific patterns of self-referential navigation and is currently believed to be involved in reactive self-referential navigation.
[0014] Therefore, in terms of the overall technical solution, an evaluation method with gradually increasing difficulty (gradually increasing spatial size) is adopted to test the patient's spatial navigation ability. At the same time, it starts from the easy to the difficult, which also improves the patient's compliance.
[0015] The subjects are given a test card in advance, on which two reference points I and II and a target point are marked, and then the card is taken back, and the subjects are asked to find the target point in the space by memory. The reference point can be made more prominent by marking it with green and yellow LEDs on the wall (corresponding to the color symbols on the card). The subjects are asked to determine the position of the unmanned vehicle (target point) through the reference point, and the target point is calibrated by remotely controlling the position of the unmanned vehicle.
[0016] The floor assembly adopts a sandwich structure, and the unmanned vehicle is located inside the sandwich structure, so that the subject cannot directly determine the position of the vehicle with the naked eye. An infrared sensor is set on the vehicle, and only when the subject walks directly above the unmanned vehicle will it be determined that the subject has found the target point. Figure 3 Several concentrically arranged unit structures are shown. The walls, floor and ceiling are all white, forming a circular enclosed space, and natural light is simulated by fluorescent lamps, so that the subject can only locate the position of the target point based on the reference point.
[0017] In order to solve the feces cleaning problem of non-human primates, the interlayer is designed as a lifting plate with one end driven by a lifting motor. One end of the lifting plate can be bent and corresponds to the sewage outlet on the base, which is convenient for daily cleaning.
[0018] In the initial state, all wall units are located on the ceiling. After the subject has identified the card and entered the center of the venue, the unit structures are lowered, and reference points I and II appear randomly on the wall cloth according to the relative positions on the card. The unmanned vehicle moves to the corresponding target point position, and the test timing can start. When the subject completes a certain stage of the test, a sound prompt is issued, the timing stops and the test results are recorded. The wall unit corresponding to the stage is folded and raised to the ceiling. The subject is prompted to return to the center of the venue for the next stage (expanding the wall range). And so on, until the subject completes all stages of the test, the evaluation can be made based on the time to reach the target point.
[0019] In addition, to increase the difficulty of the test, the number of reference points and target points can be further increased, or obstacles can be set up to interfere with the subject's line of sight when observing the reference points. To facilitate the rapid movement of the position of the obstacle, other unmanned vehicles are set up on the floor, and the obstacles are fixed on the unmanned vehicles, so that the position of the obstacles can be adjusted quickly and conveniently through the control room. In order to evaluate the self-reference navigation ability of the subject, under the premise of adding obstacles, a target controlled by a lifting mechanism is set on the unmanned vehicle, and the subject is informed in advance that the target is located near a certain obstacle, and then the time required to find the target is recorded.
[0020] In summary, by adopting the above scheme, the test results can be used to evaluate the subject's spatial reference navigation ability and self-reference navigation ability. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1 It is a perspective structural diagram of the present invention in use state I.
[0022] Figure 1a for Figure 1 Schematic diagram of the local enlarged structure of part A.
[0023] Figure 1b for Figure 1 Schematic diagram of the local enlarged structure of part B.
[0024] Figure 1c for Figure 1 Schematic diagram of the local enlarged structure of part C in the middle.
[0025] Figure 1d for Figure 1 Schematic diagram of the exploded structure of the floor assembly.
[0026] Figure 1e for Figure 1 Schematic diagram of the floor assembly in use.
[0027] Figure 2 It is an isometric side structural schematic diagram of the folding door assembly of the present invention.
[0028] Figure 2a for Figure 2 Schematic diagram of the structure of the sliding trolley assembly.
[0029] Figure 3 It is a schematic diagram of the folding process of the folding door assembly of the present invention.
[0030] Figure 4 It is the display content of the handheld PDA device of the present invention.
[0031] Figure 5 for Figure 4 The values represented by each pattern.
[0032] Figure 6 It is a schematic diagram of the principle of the spatial navigation and cognitive ability test of the present invention.
[0033] Figure 7 The figure is a schematic diagram of the testing principle of another method of using the present invention. DETAILED DESCRIPTION
[0034] The following combination Figures 1 to 7 , the specific contents of the present invention are described in detail through specific embodiments.
[0035] Example 1
[0036] The test device for evaluating the spatial positioning ability of humans or non-human primates mainly comprises a support component 1, a wall panel component 2, and a folding door component 3.
[0037] The support assembly 1 includes a floor 14, side columns 12 and a middle column 13 perpendicular to the floor 14, and a guide rail assembly 11 supported on the ceiling. The guide rail assembly 11 includes a ring rail located in the middle, radial inclined rails connected to the ring rail and evenly distributed along the circumference, side rails arranged along a regular hexagon, and an arc rail for transition. The bottom of the ring rail is supported by the middle column 13, the bottom of the arc rail and the side rail are supported by the side column 12, and the upper part of the ring rail is fixed to the ceiling through the hanging column, thereby providing sufficient support force to achieve good stability. The wall panel assembly 2 and the folding door assembly 3 are mounted on the guide rail assembly 11 at intervals. The wall panel assembly 2 and the folding door assembly 3 adopt a sliding structure to facilitate the switching of the test scene between only testing the spatial navigation level and the comprehensive evaluation of spatial navigation and cognitive level.
[0038] The floor assembly 14 includes a base 143, a lifting motor 144 arranged in the base, a lifting plate 142 whose one end is movably limited in the base 143 and driven by the lifting motor 144, and a mesh plate 141 (for the convenience of drawing, the mesh structure is not shown in the figure); one end of the lifting plate 142 is connected to the corner portion 1422 through the bending portion 1421, and a sewage outlet 1431 is provided on the base on one side of the corner portion 1422.
[0039] The wall panel assembly 2 includes a plurality of U-shaped trolley shells, running wheels 313 disposed between the trolley shells, and a strip (flexible) wall panel disposed at the bottom of the trolley shell, thereby improving the toughness of the wall panel assembly 2 and facilitating its adaptation to the curvature of the guide rail at different positions. The slide rail portion of the guide rail assembly 11 is located between the running wheels 313 and the trolley shell.
[0040] The folding door assembly 3 includes a sliding trolley assembly 31 , a telescopic column assembly 32 , and a foldable door panel assembly 33 .
[0041] Furthermore, in order to ensure smooth bidirectional movement along the guide rail assembly, the sliding trolley assembly 31 adopts a dual-drive type, and its structure specifically includes a plurality of U-shaped trolley shells, running wheels 313 arranged between the trolley shells, a running motor arranged at the input end of the end running wheels 313, a trolley connection part 3121 arranged at the bottom of the end trolley shell, a long connecting rod 315 and a short connecting rod 316, a lifting motor 314 and a control circuit.
[0042] The two ends of the short connecting rod are respectively hinged to the telescopic column assembly and the long connecting rod, and the output end of the lifting motor 314 is hinged to the short connecting rod 316 and the long connecting rod 315 at the same time. The other end of the lifting motor 314 is hinged to the bottom of the trolley shell on the side of the hinge point of the long connecting rod. Through the connecting rod assembly, it can be folded and stored when not in use, and can be freely moved in different test processes when in use, and the test mode can be switched conveniently and quickly, achieving the purpose of "one machine for multiple uses". Each trolley shell is connected in series in sequence through the male hinge ears 3123 and the female hinge ears 2122 at both ends, and the slide rail part of the guide rail assembly 11 is located between the walking wheel 313 and the trolley shell.
[0043] This embodiment takes a telescopic column assembly 32 with four sleeves as an example. In actual application, the height of the lifting frame can be freely selected, and the operation principle is basically the same. The telescopic column assembly 32 includes a plurality of coaxially sleeved reducing sleeves (322-326) in sequence, a lead screw and a driven gear 3111 arranged in the sleeves, a lifting motor reducer assembly 321 arranged at the input end of the driven gear, a hoop (3221-3261) limited by a limiting boss (3222-3262) at the bottom of each sleeve, and a universal wheel assembly 327 movably arranged at the bottom.
[0044] The output end of the lifting motor reducer assembly 321 meshes with the driven gear 3111 of the lead screw, and the input end of the lead screw is connected to the input end gear through a coupling; the coupling is preferably an elastic coupling, so that when the roof is too high and a longer sleeve is required, the axial movement of the lead screw can be compensated, thereby effectively improving the stability of the device operation. A nut that cooperates with the lead screw is arranged in the sleeve, the top of the outermost sleeve is hinged to the bottom of the hinge unit, and the bottom of the innermost sleeve is arranged with an annular groove embedded in the main body of the universal wheel component. The universal wheel component is limited by several bolts inserted into the annular groove; the universal wheel assembly includes a component body, and a walking wheel hinged on the component body through a pin and a limiting bolt. The height adjustment of the walking wheel can be achieved through the sleeve assembly, and effective buffering is achieved when the column contacts the ground to ensure the stability of the wall assembly.
[0045] The foldable door panel assembly 33 includes a plurality of hinged parts 333 fixed on each ring hoop, and a plurality of door panel assemblies 33 connected end to end in sequence to match the telescopic column sleeve; the door panel assemblies 33 are connected in sequence through the protrusions and embedded parts at both ends, and are rotatably connected to the hinged parts 333 through the protrusions, wherein one or more door panel assemblies 33 are provided with an LED display module on one side to display the corresponding numerical value. The subject clicks on the corresponding patterns one by one through the PDA device in his hand, so that the formula result on the PDA display screen is equal to the numerical value on the display screen, and the door panel assembly is folded under the drive of the lifting motor. The subject can move forward in any direction in the entire maze. After each door lock is opened once, it is reset immediately, and the display screen above the door is randomly changed to another numerical value.
[0046] The PDA device will only give Figure 6 The subject should unlock the target door lock as quickly as possible according to the "map" shown in the figure, and the test is over.
[0047] The cognitive ability is assessed by recording the number of door locks unlocked by the subject per unit time, or recording the time required for the subject to complete a cycle (i.e. the time required to unlock six door locks).
[0048] The complexity of the formula and the difficulty of calculation can be adaptively modified according to the actual situation.
[0049] Example 2
[0050] like Figure 7 As shown, in order to improve functionality, the floor assembly is a sandwich structure, the upper layer of the sandwich adopts a grid shape, and the lower part adopts a flat floor that can increase friction. Several controllable unmanned vehicles are set in the sandwich structure. The unmanned vehicle includes a drive module, a communication module, and an infrared module.
[0051]
Explanation of relevant concepts in the article
[0052] [Spatial navigation] refers to the ability of a person to determine the route based on his own and environmental clues when moving between different locations. It includes multiple complex cognitive and perceptual processes. Spatial reference navigation relies on cognitive maps and requires people to remember and analyze the geographical distribution of the entire space from an exploratory perspective, including the location of spatial landmarks, the distance and direction information between the starting point and the target location, etc. Its structural basis is mainly located in the hippocampus and parahippocampal gyrus. When people move in various environments, they need to rely on different spatial representations, including two basic representation methods: self-reference navigation decodes spatial information with its own location as the center to maintain a sense of direction when moving; spatial reference navigation relies on cognitive maps and requires people to remember and analyze the geographical distribution of the entire space from an exploratory perspective, including the location of spatial landmarks, the distance and direction information between the starting point and the target location, etc. When people move in an environment, the two navigation strategies are usually inseparable. A landmark can be identified through both spatial reference navigation and self-reference navigation. Excellent navigation uses different spatial information to transform between self-reference and spatial reference to maximize navigation efficiency.
[0053] The water maze test was designed by Richard Morris in 1981 and applied to the study of brain mechanisms of learning and memory. It has become an important experimental method for judging animal learning and memory over the past two decades. In recent years, it has been widely used in research fields such as neurophysiology, neuropsychology, neuropharmacology, and geriatrics. The water maze experiment is based on forcing animals to swim in a pool and testing their learning and memory abilities of spatial position and orientation by asking them to find a platform set up in the water. Since the water maze tests the spatial position and orientation of animals, the animals' perception and memory of space must be based on fixed reference objects.
[0054] Zhougong] Closed rotating area path maze.
[0055] [Elastic coupling] The elastic coupling is an integrally formed metal elastomer, usually cut from a metal round bar. Commonly used materials include aluminum alloy, stainless steel, and engineering plastics. It is suitable for various deviations and precise transmission of torque. Its improved structure was disclosed in German patent DE1939410A1.
[0056] Description of reference numerals:
[0057] 1Support components
[0058] 11 Guide rail assembly
[0059] 12 side posts
[0060] 13 Middle Column
[0061] 14 Floor Components
[0062] 141 Stencil
[0063] 142 lifting plate
[0064] 1421 Bending section
[0065] 1422 corner part
[0066] 143 base
[0067] 1431 sewage outlet
[0068] 144 lifting motor
[0069] 2Wall Panel Components
[0070] 3 Folding door components
[0071] 31 Sliding trolley assembly
[0072] 311 Travel Motor
[0073] 312 trolley housing
[0074] 3121 trolley connection
[0075] 3122 Female hinged ear
[0076] 3123 Male hinged lug
[0077] 313 Travel Wheel
[0078] 314 lifting motor
[0079] 315 long connecting rod
[0080] 316 short connecting rod
[0081] 32 telescopic column assembly
[0082] 321 lifting motor reducer assembly
[0083] 3111 driven gear
[0084] 322 first casing
[0085] 3221 First Hoop
[0086] 3222 first limit boss
[0087] 323 Second casing
[0088] 3231 Second hoop
[0089] 3232 second limiting boss
[0090] 324 third casing
[0091] 3241 Third Hoop
[0092] 3242 third limit boss
[0093] 325 fourth casing
[0094] 3251 Fourth Hoop
[0095] 3252 fourth limit boss
[0096] 326 Fifth Casing
[0097] 3261 Fifth Hoop
[0098] 3262 fifth limit boss
[0099] 327 universal wheel assembly
[0100] 33 Door panel assembly
[0101] 331 Door panel raised part
[0102] 332 Door panel embedded part
[0103] 333 hinge
[0104] A1 Reference Point I
[0105] A2 Reference Point II
[0106] Subject B
[0107] C Target Door Lock
[0108] D. Unmanned vehicle.
Claims
1. A test device for evaluating the spatial positioning ability of humans or non-human primates, characterized in that: It comprises a support assembly (1), a wall panel assembly (2), and a folding door assembly (3); The support assembly (1) comprises a floor assembly (14), side columns (12) and a middle column (13) perpendicular to the floor assembly (14), and a guide rail assembly (11) supported on the ceiling; the floor assembly (14) comprises a base (143), a lifting motor (144) arranged in the base, a lifting plate (142) with one end movably limited in the base (143) and driven by the lifting motor (144), and a mesh plate (141); one end of the lifting plate (142) is connected to a corner portion (1422) via a bending portion (1421), and a sewage outlet (1431) is provided on the base on one side of the corner portion (1422); The wall panel assembly (2) comprises a plurality of U-shaped trolley shells, running wheels (313) arranged between the trolley shells, and a strip-shaped wall panel arranged at the bottom of the trolley shells; the slide rail portion of the guide rail assembly (11) is located between the running wheels (313) and the trolley shells; The folding door assembly (3) comprises a sliding trolley assembly (31), a telescopic column assembly (32), and a foldable door panel assembly (33); The sliding trolley assembly (31) comprises a plurality of U-shaped trolley shells, running wheels (313) arranged between the trolley shells, a running motor arranged at the input end of the end running wheels (313), a trolley connection portion arranged at the bottom of the end trolley shell, a long connecting rod (315) and a short connecting rod (316) hinged between the trolley connection portion and the telescopic column assembly (32), a lifting motor (314) whose output end is located between the two connecting rods and whose fixed end is hinged to the bottom of the trolley shell, and a control circuit; each trolley shell is connected in series in sequence through a male hinge ear and a female hinge ear at both ends, and the slide rail portion of the guide rail assembly (11) is located between the running wheel (313) and the trolley shell; The telescopic column assembly (32) comprises a plurality of coaxially arranged reducing sleeves, a lead screw and a driven gear arranged in the sleeves, a lifting motor reducer assembly (321) arranged at the input end of the driven gear, a hoop limited by a limiting boss at the bottom of each sleeve, and a universal wheel assembly (327) movably arranged at the bottom; The foldable door panel assembly (33) comprises a plurality of hinged parts (333) fixed on each ring hoop, and a plurality of door panel assemblies (33) connected end to end in sequence and matched with telescopic column sleeves; the door panel assemblies (33) are connected in sequence through raised parts and embedded parts at both ends, and are rotatably connected to the hinged parts (333) through the raised parts, wherein one side of one or more door panel assemblies (33) is provided with an LED display module.
2. The test device for evaluating the spatial positioning ability of humans or non-human primates according to claim 1, characterized in that: The ceiling is equipped with several infinitely adjustable LEDs for simulating lighting conditions.
Citation Information
Patent Citations
Method and device for reinforcing spatial memory of water maze laboratory animal
CN101142900A
High-grade full-automatic intelligent analysis system of Morris water maze
CN102422818A
elastic claw coupling
DE1939410A1
Testing device for evaluating spatial positioning capability of human or non-human primates
CN213486396U