A kind of pharmaceutical composition for insomnia and preparation method thereof

Abstract

The invention relates to a pharmaceutical composition for insomnia and a preparation method thereof. The pharmaceutical composition comprises 100-200 parts of Jujube Seed, 80-120 parts of Poria, 30-50 parts of Chenpi, 50-70 parts of Acanthopanax, Bupleuri 15-25 parts, 5-15 parts of licorice, 40-60 parts of r-aminobutyric acid, the preparation method is to take jujube kernels and stir-fry them, then physically press them to extract the oil for later use, mix the oil cake with Poria cocos and licorice, and grind them at low temperature, and add tangerine peel and Acanthopanax 1. After the Bupleurum root is broken, leak it with 55% edible ethanol, combine the seepage to recover the ethanol, concentrate under reduced pressure, add an appropriate amount of Suanzaoren Poria wall broken powder, spray dry, pass through a 80-mesh sieve, and grind r-aminobutyric acid Pass through 100 mesh, mix with spray-dried powder and remaining wall-broken powder, granulate with purified water, dry, add jujube seed oil, and make tablets, capsules, granules, and pills. The medicine is effective in treating insomnia and relieving various anxiety, and has no toxic and side effects.

Description

technical field

[0001] The invention relates to the field of medical inventions, in particular to a pharmaceutical composition for insomnia and a preparation method thereof. Background technique

[0002] Insomnia is the enemy of human health. Long-term insomnia affects normal work and life, mental weakness, mental disorders, psychological disorders, suicide, induces heart, brain and other physical diseases, and accidents.

[0003] Long-term insomnia leads to decreased immunity: when a disease occurs, if a person suffers from insomnia for a short period of time, symptoms such as fatigue, dizziness, backache, tinnitus, palpitation and shortness of breath will occur; Force is reduced. Good sleep will cause the human body to produce muramic acid factor, which can promote the increase of human white blood cells, thereby promoting the activation of macrophages, and the human immune function will be significantly enhanced, thus effectively preventing the invasion of bacteria and v...

Examples

Embodiment 1

[0058] Prescription: Suanzaoren 150g, Poria 100g, Chenpi 40g, Acanthopanax 60g, Bupleurum 20g, Licorice 10g, r-aminobutyric acid 50g.

[0059] The prescription of embodiment 1 is made by any of the following preparation methods.

[0060] Preparation method one:

[0061] 1) Take 1 / 2 of the Chinese date kernels and stir-fry them, then press them physically to get the Chinese date kernel oil and Chinese date kernel oil cake, and set aside;

[0062] 2) After taking 1 / 2 of the recipe amount of Poria cocos and the recipe amount of licorice to break the wall, mix it with the jujube seed oil cake in step 1), and crush it to 500 mesh at low temperature, then take the recipe amount of tangerine peel, acanthopanax, and firewood After breaking the wall, mix well, leak 3 times with 8 times the amount, 6 times the amount, and 6 times the amount of 55% edible ethanol successively, combine the seepage liquid, recover the ethanol, and concentrate under reduced pressure at 60°C to a density of...

Embodiment 2

[0086] Prescription: Suanzaoren 100g, Poria cocos 80g, tangerine peel 30g, Acanthopanax 50g, Bupleurum 15g, licorice 5g, r-aminobutyric acid 40g

[0087] The prescription of embodiment 2 is made by any of the following preparation methods.

[0088] Preparation method one:

[0089] 1) Take 1 / 2 of the Chinese date kernels and stir-fry them, then press them physically to get the Chinese date kernel oil and Chinese date kernel oil cake, and set aside;

[0090] 2) After taking 1 / 2 of the recipe amount of Poria cocos and the recipe amount of licorice to break the wall, mix it with the jujube seed oil cake in step 1), and crush it to 500 mesh at low temperature, then take the recipe amount of tangerine peel, acanthopanax, and firewood After breaking the wall, mix well, leak 3 times with 8 times the amount, 6 times the amount, and 6 times the amount of 55% edible ethanol successively, combine the seepage liquid, recover the ethanol, and concentrate under reduced pressure at 60°C to a...

Embodiment 3

[0114] Prescription: Suanzaoren 200g, Poria cocos 120g, tangerine peel 50g, Acanthopanax 70g, Bupleurum 25g, licorice 15g, r-aminobutyric acid 60g

[0115] The prescription of embodiment 3 is made by any of the following preparation methods.

[0116] Preparation method one:

[0117] 1) Take 1 / 2 of the Chinese date kernels and stir-fry them, then press them physically to get the Chinese date kernel oil and Chinese date kernel oil cake, and set aside;

[0118] 2) After taking 1 / 2 of the recipe amount of Poria cocos and the recipe amount of licorice to break the wall, mix it with the jujube seed oil cake in step 1), and crush it to 500 mesh at low temperature, then take the recipe amount of tangerine peel, acanthopanax, and firewood After breaking the wall, mix well, leak 3 times with 8 times the amount, 6 times the amount, and 6 times the amount of 55% edible ethanol successively, combine the seepage liquid, recover the ethanol, and concentrate under reduced pressure at 60°C to...

technical field

[0001] The invention relates to the field of medical inventions, in particular to a pharmaceutical composition for insomnia and a preparation method thereof. Background technique

[0002] Insomnia is the enemy of human health. Long-term insomnia affects normal work and life, mental weakness, mental disorders, psychological disorders, suicide, induces heart, brain and other physical diseases, and accidents.

[0003] Long-term insomnia leads to decreased immunity: when a disease occurs, if a person suffers from insomnia for a short period of time, symptoms such as fatigue, dizziness, backache, tinnitus, palpitation and shortness of breath will occur; Force is reduced. Good sleep will cause the human body to produce muramic acid factor, which can promote the increase of human white blood cells, thereby promoting the activation of macrophages, and the human immune function will be significantly enhanced, thus effectively preventing the invasion of bacteria and v...

Examples

Embodiment 1

[0058] Prescription: Suanzaoren 150g, Poria 100g, Chenpi 40g, Acanthopanax 60g, Bupleurum 20g, Licorice 10g, r-aminobutyric acid 50g.

[0059] The prescription of embodiment 1 is made by any of the following preparation methods.

[0060] Preparation method one:

[0061] 1) Take 1 / 2 of the Chinese date kernels and stir-fry them, then press them physically to get the Chinese date kernel oil and Chinese date kernel oil cake, and set aside;

[0062] 2) After taking 1 / 2 of the recipe amount of Poria cocos and the recipe amount of licorice to break the wall, mix it with the jujube seed oil cake in step 1), and crush it to 500 mesh at low temperature, then take the recipe amount of tangerine peel, acanthopanax, and firewood After breaking the wall, mix well, leak 3 times with 8 times the amount, 6 times the amount, and 6 times the amount of 55% edible ethanol successively, combine the seepage liquid, recover the ethanol, and concentrate under reduced pressure at 60°C to a density of...

Embodiment 2

[0086] Prescription: Suanzaoren 100g, Poria cocos 80g, tangerine peel 30g, Acanthopanax 50g, Bupleurum 15g, licorice 5g, r-aminobutyric acid 40g

[0087] The prescription of embodiment 2 is made by any of the following preparation methods.

[0088] Preparation method one:

[0089] 1) Take 1 / 2 of the Chinese date kernels and stir-fry them, then press them physically to get the Chinese date kernel oil and Chinese date kernel oil cake, and set aside;

[0090] 2) After taking 1 / 2 of the recipe amount of Poria cocos and the recipe amount of licorice to break the wall, mix it with the jujube seed oil cake in step 1), and crush it to 500 mesh at low temperature, then take the recipe amount of tangerine peel, acanthopanax, and firewood After breaking the wall, mix well, leak 3 times with 8 times the amount, 6 times the amount, and 6 times the amount of 55% edible ethanol successively, combine the seepage liquid, recover the ethanol, and concentrate under reduced pressure at 60°C to a...

Embodiment 3

[0114] Prescription: Suanzaoren 200g, Poria cocos 120g, tangerine peel 50g, Acanthopanax 70g, Bupleurum 25g, licorice 15g, r-aminobutyric acid 60g

[0115] The prescription of embodiment 3 is made by any of the following preparation methods.

[0116] Preparation method one:

[0117] 1) Take 1 / 2 of the Chinese date kernels and stir-fry them, then press them physically to get the Chinese date kernel oil and Chinese date kernel oil cake, and set aside;

[0118] 2) After taking 1 / 2 of the recipe amount of Poria cocos and the recipe amount of licorice to break the wall, mix it with the jujube seed oil cake in step 1), and crush it to 500 mesh at low temperature, then take the recipe amount of tangerine peel, acanthopanax, and firewood After breaking the wall, mix well, leak 3 times with 8 times the amount, 6 times the amount, and 6 times the amount of 55% edible ethanol successively, combine the seepage liquid, recover the ethanol, and concentrate under reduced pressure at 60°C to...

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