An adjustable multi-partitioned airbag multi-channel post-installed source applicator in the rectal cavity

Abstract

The present invention relates to an adjustable multi-partitioned airbag multi-channel post-installed source applicator in a rectal cavity, comprising a multi-channel lead blocking source applicator and a multi-partitioned airbag, wherein the multi-channel lead blocking source applicator comprises a plurality of replaceable independent modules, which are combined and spliced ​​to form a columnar multi-channel lead blocking source applicator; an arc portion is arranged at the center of each replaceable independent module, and the arc portion of each replaceable independent module forms a central channel after the plurality of replaceable independent modules are combined and spliced; a source guide tube channel extending along the axial direction is arranged inside each replaceable independent module, and the central channel and the source guide tube channel are both used for retaining a source guide tube; the multi-partitioned airbag is sleeved on the outer peripheral wall of the multi-channel lead blocking source applicator, and each multi-partitioned airbag can be inflated separately to form a symmetrical or asymmetrical shape, thereby fixing the multi-channel lead blocking source applicator in the rectal cavity.

Description

Technical Field

[0001] The invention relates to the technical field of medical devices, and in particular to an adjustable multi-partitioned airbag multi-channel post-installed source applicator in a rectal cavity. Background Art

[0002] Treatment of rectal cancer usually includes surgery, chemotherapy and radiotherapy. Radiotherapy is an important part of comprehensive treatment of rectal cancer. About 70% of patients need to receive radiotherapy during treatment. The internationally recommended treatment model for rectal cancer is direct surgery for early rectal cancer, and surgery after synchronous radiotherapy and chemotherapy for mid- and late-stage rectal cancer. However, surgical treatment of low-position rectal cancer cannot preserve the anus.

[0003] Due to the shortcomings of surgical treatment, the high incidence of TME complications and the greater risk of affecting normal function, while chemoradiotherapy can achieve complete remission of the patient's condition, with a PCR rate of 15% to 25%, and the ability to preserve the anus, more and more patients tend to choose non-surgical treatment options such as chemotherapy and radiotherapy.

[0004] Brachytherapy treatment includes contact X-ray brachytherapy and high-dose rate afterloading therapy. The treatment equipment used for contact X-ray brachytherapy is, for example, Philips RT 50, which has the following characteristics: low voltage 50kV, short focal length 4cm, high output rate X-ray absorption mainly in the first 2cm, narrow tube, easy to hold, and can be placed in a special colonoscope. However, domestic radiotherapy centers do not have modified treatment equipment.

[0005] High dose rate afterloading therapy 192 Ir is used as a radiation source. 192 The physical characteristics of Ir are half-life of 74.5 days, energy of 355keV, lead equivalent of half-value layer of 0.24cm, and irradiation dose can be prescribed at any depth, generally 10mm from the surface of the applicator can reach 100% of the prescribed dose. At present, all large radiotherapy centers in China have high-dose rate afterloading treatment equipment.

[0006] The main limiting factor for the clinical application of high-dose rate afterloading for rectal cancer in the existing technology is the applicator. There are multiple vulnerable organs in the treatment area of ​​rectal cancer, including the bladder, rectum, uterus, vagina, urethra, and skin. The existing technology usually uses a shielding protector to reduce the irradiation of normal tissues, but the shielding protector will cause discomfort to the patient.

[0007] In addition, the applicator in the prior art generally has only one radiation source channel, the distance between the radiation source and the surface cannot be adjusted, the applicator is not long enough, and the upper limit of the tumor cannot be reached. Summary of the invention

[0008] The present invention aims to provide an adjustable multi-partitioned airbag multi-channel afterloading applicator in the rectal cavity. The technical problems to be solved include how to adjust the prescribed dose in the tumor area and the dose to organs at risk in the non-tumor area in multiple directions under equal conditions, so as to realize the precise implementation of high-dose rate afterloading therapy.

[0009] The purpose of the present invention is to solve the deficiencies of the prior art and to provide an adjustable multi-partitioned airbag multi-channel post-installed source applicator in the rectal cavity, comprising a multi-channel lead blocking source applicator and a multi-partitioned airbag, wherein the multi-channel lead blocking source applicator comprises a plurality of replaceable independent modules, which are combined and spliced ​​to form a columnar multi-channel lead blocking source applicator; an arc portion is arranged at the center of each replaceable independent module, and the arc portion of each replaceable independent module forms a central channel after the plurality of replaceable independent modules are combined and spliced; a source guide tube channel extending along the axial direction is arranged inside each replaceable independent module, and the central channel and the source guide tube channel are both used for retaining the source guide tube; the multi-partitioned airbag is sleeved on the outer peripheral wall of the multi-channel lead blocking source applicator, and each multi-partitioned airbag can be inflated separately to form a symmetrical or asymmetrical shape, thereby fixing the multi-channel lead blocking source applicator in the rectal cavity.

[0010] The material of the replaceable independent module is tungsten alloy or resin.

[0011] Preferably, the diameter of the central channel is 1 mm to 5 mm.

[0012] Preferably, the diameter of the source tube channel is 1 mm to 5 mm.

[0013] Preferably, a virtual straight line is made on the cross-section of the multi-channel lead blocking source applicator, passing through the center of the central channel and the center of the source tube channel at the same time. The virtual straight line extends to the outermost edge of the replaceable independent module and intersects with the outermost edge to form a virtual intersection. The distance between the center of the source tube channel and the virtual intersection is 0.1 cm to 1 cm.

[0014] Preferably, the thickness of the replaceable independent module is 0.5 cm to 1.5 cm; the thickness of the replaceable independent module 11 refers to the distance from the center of the central channel 13 to any point on the outermost arc edge line of the cross section of the replaceable independent module 11 on the cross section of the replaceable independent module 11.

[0015] Preferably, the multi-channel lead blocking source applicator includes 6 replaceable independent modules, each of which has a central angle of 60 degrees, and the 6 replaceable independent modules are combined and spliced ​​to form a cylindrical multi-channel lead blocking source applicator.

[0016] Further preferably, the inner diameter of the multi-channel lead blocking source applicator is 2-3 cm and the length is 20-25 cm.

[0017] Beneficial Effects

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] The adjustable multi-partitioned airbag multi-channel afterloading source applicator in the rectal cavity of the present invention adopts a combination of a multi-channel lead blocking source applicator and a multi-partitioned airbag, and has multiple source guide tube channels to choose from. According to the location of the patient's tumor, a suitable source guide tube channel and a corresponding replaceable module are selected. The airbags on the tumor side and the healthy side can be inflated separately and independently in a planned manner according to the thickness of the tumor, so as to adjust the tumor area prescription dose and the non-tumor area endangered organ dose in multiple directions according to the location of the source guide tube, the different shielding capabilities of the replaceable modules to the rays, the ability of the airbag to adjust the distance from the source guide tube to the intestinal wall, and other conditions, thereby realizing the precise implementation of high-dose rate afterloading treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The accompanying drawings are used to provide a further understanding of the technical solution of the present invention and constitute a part of the specification. Together with the specific implementation methods of the present application, they are used to explain the technical solution of the present invention and do not constitute a limitation on the technical solution of the present invention.

[0021] Figure 1 It is a schematic diagram of the cross-sectional structure of the multi-channel lead blocking source applicator described in the present invention.

[0022] Figure 2 It is a schematic diagram of the longitudinal cross-section structure of the multi-channel lead blocking source applicator described in the present invention.

[0023] Figure 3 It is a schematic diagram of the structure of a common applicator with an external multi-partitioned air bag.

[0024] Figure 4 It is a schematic structural diagram of the cross section of the multi-channel lead blocking source applicator and the multi-partitioned airbags after being combined according to the present invention. DETAILED DESCRIPTION

[0025] The present invention is described in more detail hereinafter to facilitate understanding of the present invention.

[0026] like Figures 1 to 4As shown, the adjustable multi-compartment airbag multi-channel post-installed source applicator in the rectal cavity described in the present invention includes a multi-channel lead blocking source applicator 1 and a multi-compartment airbag 2, the multi-channel lead blocking source applicator 1 includes a plurality of replaceable independent modules 11, and the plurality of replaceable independent modules 11 are combined and spliced ​​to form a columnar multi-channel lead blocking source applicator 1; an arc portion 12 is arranged at the center of each replaceable independent module, and the arc portion 12 of each replaceable independent module forms a central channel 13 after the plurality of replaceable independent modules 11 are combined and spliced; a source guide tube channel 14 extending along the axial direction is arranged inside each replaceable independent module, and the central channel 13 and the source guide tube channel 14 are both used for retaining a source guide tube 15; the multi-compartment airbag 2 is sleeved on the outer peripheral wall of the multi-channel lead blocking source applicator 1, and each multi-compartment airbag can be inflated separately to form a symmetrical or asymmetrical shape, thereby fixing the multi-channel lead blocking source applicator 1 in the rectal cavity.

[0027] The material of the replaceable independent module 11 is tungsten alloy or resin.

[0028] Preferably, the diameter of the central channel 13 is 1 mm to 5 mm.

[0029] Preferably, the diameter of the source tube channel 14 is 1 mm to 5 mm.

[0030] Preferably, a virtual straight line is made on the cross section of the multi-channel lead blocking source applicator 1, passing through the center of the central channel 13 and the center of the source tube channel 14 at the same time. The virtual straight line extends to the outermost edge of the replaceable independent module 11 and intersects with the outermost edge to form a virtual intersection. The distance between the center of the source tube channel 14 and the virtual intersection is 0.1 cm to 1 cm.

[0031] Preferably, the thickness of the replaceable independent module 11 is 0.5 cm to 1.5 cm; the thickness of the replaceable independent module 11 refers to the distance from the center of the central channel 13 to any point on the outermost arc edge line of the cross section of the replaceable independent module 11 on the cross section of the replaceable independent module 11.

[0032] Preferably, the multi-channel lead blocking source applicator 1 comprises 6 replaceable independent modules 11, each of which has a central angle of 60 degrees, and the 6 replaceable independent modules are combined and spliced ​​to form a cylindrical multi-channel lead blocking source applicator.

[0033] Further preferably, the inner diameter R of the multi-channel lead blocking source applicator 1 is 2-3 cm, and the length L is 20-25 cm.

[0034] The multi-channel lead blocking source applicator 1 described in the present invention is modified on the basis of a single-channel columnar source applicator. In a preferred embodiment, the adjustable multi-partitioned airbag multi-channel afterloading source applicator described in the present invention has a total of 7 channels for the indwelling source tube to choose from. According to the patient's tumor location, the appropriate source tube channel and the corresponding replaceable module are selected. The airbags on the tumor side and the healthy side can be inflated separately and independently in a planned manner according to the thickness of the tumor, so as to achieve multi-directional adjustment of the tumor area prescription dose and the non-tumor area endangered organ dose according to the location of the source tube, the different shielding capabilities of the replaceable modules to the radiation, the ability of the airbag to adjust the distance from the source tube to the intestinal wall, and other conditions, thereby realizing the precise implementation of high-dose rate afterloading therapy.

[0035] The rectal cavity adjustable multi-divided airbag multi-channel afterloading source applicator of the present invention can realize high-dose rate afterloading, afterloading treatment in the rectal cavity, and introduce the source into the guide tube. 192 Ir radiation source, through accurate dose calculation, places the tumor in the dose "sweet spot" to optimize tumor treatment. It can accurately protect the unirradiated intestinal wall and reduce the toxic and side effects associated with radiotherapy.

[0036] The above describes the preferred embodiments of the present invention, but it is not intended to limit the present invention. Those skilled in the art may make improvements and changes to the embodiments disclosed herein without departing from the scope and spirit of the present invention.

Claims

1. An adjustable multi-partitioned airbag multi-channel post-installed source applicator in the rectal cavity, characterized in that: The adjustable multi-partitioned airbag multi-channel post-installed source applicator in the rectal cavity comprises a multi-channel lead blocking source applicator and a multi-partitioned airbag, wherein the multi-channel lead blocking source applicator comprises a plurality of replaceable independent modules, which are combined and spliced ​​to form a columnar multi-channel lead blocking source applicator; an arc portion is arranged at the center of each replaceable independent module, and the arc portion of each replaceable independent module forms a central channel after the plurality of replaceable independent modules are combined and spliced; a source guide tube channel extending along the axial direction is arranged inside each replaceable independent module, and the central channel and the source guide tube channel are both used for retaining the source guide tube; the multi-partitioned airbag is sleeved on the outer peripheral wall of the multi-channel lead blocking source applicator, and each multi-partitioned airbag can be inflated separately to form a symmetrical or asymmetrical shape, thereby fixing the multi-channel lead blocking source applicator in the rectal cavity; The multi-channel lead blocking source applicator comprises 6 replaceable independent modules, each of which has a central angle of 60 degrees, and the 6 replaceable independent modules are combined and spliced ​​to form a cylindrical multi-channel lead blocking source applicator; The inner diameter of the multi-channel lead blocking source applicator is 2-3 cm and the length is 20-25 cm; The material of the replaceable independent module is tungsten alloy or resin; A virtual straight line is made on the cross section of the multi-channel lead blocking source applicator, passing through the center of the central channel and the center of the source guide tube channel at the same time. The virtual straight line extends to the outermost edge of the replaceable independent module and intersects with the outermost edge to form a virtual intersection. The distance between the center of the source guide tube channel and the virtual intersection is 0.1 cm to 1 cm; The thickness of the replaceable independent module is 0.5 cm to 1.5 cm; the thickness of the replaceable independent module refers to the distance from the center of the central channel to any point on the outermost arc edge line of the cross section of the replaceable independent module on the cross section of the replaceable independent module; The adjustable multi-compartment airbag multi-channel afterloading source applicator in the rectal cavity adopts a combination of a multi-channel lead blocking source applicator and a multi-compartment airbag, and has multiple source guide tube channels for selection. According to the patient's tumor position, a suitable source guide tube channel and a corresponding replaceable module are selected; the airbags on the tumor side and the healthy side can be inflated separately and independently in a planned manner according to the thickness of the tumor, so as to realize the different shielding capabilities of the replaceable modules to the radiation according to the position of the source guide tube, the ability of the airbag to adjust the distance from the source guide tube to the intestinal wall, and the multi-directional adjustment of the tumor area prescription dose and the non-tumor area organ-at-risk dose, thereby realizing the precise implementation of high-dose rate afterloading treatment; The diameter of the central channel is 1 mm to 5 mm; The diameter of the source guide tube channel is 1 mm to 5 mm; The adjustable multi-compartment balloon multi-channel afterloading source applicator in the rectal cavity has a total of 7 channels for indwelling source tubes for selection. According to the patient's tumor location, an appropriate source tube channel and a corresponding replaceable module are selected; the balloons on the tumor side and the healthy side can be inflated separately and independently in a planned manner according to the thickness of the tumor, so as to realize the different shielding capabilities of the replaceable modules to the radiation according to the location of the source tube, the ability of the balloon to adjust the distance from the source tube to the intestinal wall, and the multi-directional adjustment of the tumor area prescription dose and the non-tumor area organ-at-risk dose, thereby realizing the precise implementation of high-dose rate afterloading therapy; The rectal cavity adjustable multi-divided airbag multi-channel afterloading source applicator can achieve high dose rate afterloading, rectal cavity afterloading treatment, and introduce the source into the guide tube. The radiation source optimizes tumor treatment through precise dose calculation, accurately protects the unirradiated intestinal wall, and reduces radiotherapy-related toxic and side effects.

Images