Membrane oxygenator

Abstract

The present invention provides a membrane oxygenator, comprising: a housing having a first air cavity, a gas exchange cavity, and a second air cavity arranged in sequence along a vertical direction; a partition disposed within the first air cavity and the gas exchange cavity to divide the first air cavity into a first inner gas cavity and a first outer gas cavity, and further to divide the gas exchange cavity into an inner gas exchange cavity and an outer gas exchange cavity; a communication port between the inner gas exchange cavity and the outer gas exchange cavity; a blood inlet communicating with the inner gas exchange cavity; a blood outlet communicating with the outer gas exchange cavity; a gas inlet communicating with the first outer gas cavity; a first gas outlet communicating with the second air cavity; and a second gas outlet communicating with the first inner gas cavity; wherein the partition is provided with a first flow port located within the first air cavity; and the first flow port is configured to be openable and closable. The present invention solves the problem of low gas exchange efficiency in conventional membrane oxygenators.

Description

Technical Field

[0001] The present invention relates to the field of medical equipment, and in particular to a membrane oxygenator. Background Art

[0002] A membrane oxygenator, also known as a membrane artificial lung, is an artificial device that replaces the natural function of the human lung, oxygenating blood and removing carbon dioxide outside the body. Hollow fiber membrane oxygenators are the most similar to human physiology today and are commonly used in intraoperative and postoperative cardiac surgery, as well as in respiratory support. They are characterized by the absence of direct contact between blood and air, resulting in a highly biomimetic design.

[0003] However, existing membrane oxygenators all have a single-chamber structure, and blood and gas can only flow in one direction (co-directional or counter-directional). Under the condition of the same gas inlet flow rate, the exchange rate of carbon dioxide and oxygen between gas and blood is low. Summary of the Invention

[0004] The main purpose of the present invention is to provide a membrane oxygenator to solve the problem of low gas exchange efficiency of the membrane oxygenator in the prior art.

[0005] To achieve the above-mentioned object, the present invention provides a membrane oxygenator, comprising: a housing having a first air chamber, a gas exchange chamber, and a second air chamber arranged in sequence along a vertical direction, the gas exchange chamber communicating with both the first and second air chambers; a partition connected to the housing, disposed within the first and gas exchange chambers to divide the first air chamber into a first inner gas chamber and a first outer gas chamber, and further to divide the gas exchange chamber into an inner gas exchange chamber and an outer gas exchange chamber; a communication port being defined between the inner gas exchange chamber and the outer gas exchange chamber; a blood inlet communicating with the inner gas exchange chamber; a blood outlet disposed on the housing and communicating with the outer gas exchange chamber; the blood outlet and the blood inlet being located on opposite sides of the partition and both being located above the communication port; a gas inlet disposed on the housing and communicating with the first outer gas chamber; a first gas outlet disposed on the housing and communicating with the second air chamber; and a second gas outlet disposed on the housing and communicating with the first inner gas chamber; wherein the partition is provided with a first flow port located within the first air chamber; and the first flow port is configured to be openable and closable.

[0006] Furthermore, the membrane oxygenator also includes a first seal and a second seal, both of which are arranged in the shell and connected to the shell, and the first seal and the second seal are spaced apart in the vertical direction; the first seal is located above the second seal, so that the first seal and the second seal separate the shell into a first air cavity, a gas exchange cavity, and a second air cavity.

[0007] Furthermore, the membrane oxygenator further comprises: a hollow fiber membrane, one end of the hollow fiber membrane being connected to the first sealing member and communicating with the first air cavity, and the other end of the hollow fiber membrane being connected to the second sealing member and communicating with the second air cavity, so that the gas passing through the gas exchange cavity flows in the hollow fiber membrane.

[0008] Furthermore, the membrane oxygenator further includes: a blood delivery tube, the blood delivery tube being inserted into the housing, the blood delivery tube having a first delivery end and a second delivery end disposed opposite to each other, the first delivery end being located outside the housing, the blood inlet being located at the first delivery end, and the second delivery end being in communication with the gas exchange lumen; wherein the first sealing member is disposed around the blood delivery tube and between the blood delivery tube and the housing.

[0009] Furthermore, the membrane oxygenator further includes: a first support portion connected to the housing; and a second sealing member disposed around the first support portion and between the first support portion and the housing.

[0010] Furthermore, the partition is a tubular structure having a first connecting end and a second connecting end, the first connecting end being connected to the top of the shell, and the second connecting end extending toward the bottom of the shell and being located in the gas exchange chamber; wherein the second connecting end forms a connecting port with the bottom of the gas exchange chamber.

[0011] Furthermore, the first flow opening is an annular opening, and the annular opening is arranged around the circumference of the partition.

[0012] Furthermore, the membrane oxygenator further comprises: an annular valve, which is arranged at the first flow port so that the first flow port can be opened and closed.

[0013] Furthermore, there are multiple first flow openings, and the multiple first flow openings are arranged at intervals around the circumference of the partition.

[0014] Furthermore, the membrane oxygenator further comprises: a plurality of first control valves, which are arranged in one-to-one correspondence with the plurality of first flow ports, and each first control valve is arranged at a corresponding first flow port.

[0015] Furthermore, the membrane oxygenator further comprises: a second control valve provided on the first gas outlet to control the opening and closing of the first gas outlet; and / or a third control valve provided on the second gas outlet to control the opening and closing of the second gas outlet.

[0016] Furthermore, the shell includes a first shell part, a second shell part and a third shell part, and the first shell part, the third shell part and the second shell part are arranged in sequence from top to bottom; the first shell part forms a first air cavity, the second shell part forms a second air cavity, and the third shell part forms a gas exchange cavity; wherein the first seal, the second seal and the hollow fiber membrane are all arranged in the gas exchange cavity.

[0017] The membrane oxygenator of the present invention includes a partition provided within the housing, which can divide the first gas cavity into a first gas inner cavity and a first gas outer cavity, and the gas exchange cavity into a gas exchange inner cavity and a gas exchange outer cavity. During operation, blood enters the gas exchange inner cavity through the blood inlet, then enters the gas exchange outer cavity through the communication port, and finally flows out through the blood outlet. Gas passing through the first gas inner cavity can switch its flow direction under the influence of the first gas outlet, the second gas outlet, and the first flow port. This arrangement enables the change of gas flow direction, and the membrane oxygenator can achieve this switching of gas flow direction during use.

[0018] When the first flow port and the first gas outlet are closed and the second gas outlet is open (operating condition 1), gas enters the first gas outer chamber from the gas inlet, then flows through the gas exchange outer chamber and into the second gas chamber. Gas entering the second gas chamber flows into the gas exchange inner chamber, then into the first gas inner chamber, and finally out through the second gas outlet provided on the first gas inner chamber. This way, with the same gas flow rate, the gas flow rate is faster, improving gas exchange efficiency.

[0019] When the first flow port and the first gas outlet are open and the second gas outlet is closed (this is working condition 2), the gas enters the first gas outer cavity through the gas inlet and enters the first gas inner cavity through the first flow port. At this time, the gas in the first gas outer cavity passes through the gas exchange outer cavity and completes gas exchange with the blood before entering the second gas cavity. The gas in the first gas inner cavity passes through the gas exchange inner cavity and completes gas exchange with the blood before entering the second gas cavity, so that the gas flows out through the first gas outlet provided on the second gas cavity. In this way, the blood in the gas exchange inner cavity flows in the same direction as the gas, and the blood in the gas exchange outer cavity flows in the opposite direction to the gas. The blood and gas of the membrane oxygenator first flow in the same direction and then flow in the opposite direction, which improves the gas exchange rate. In addition, in working condition 1, there is a risk of condensed water accumulating and blocking the gas channel. When the air pressure in the gas chamber increases to a certain value due to condensed water blocking the gas channel, it is necessary to switch back to working condition 2 and use the airflow from top to bottom to flush the airway and remove the condensed water. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The accompanying drawings, which constitute part of this application, are intended to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are intended to explain the present invention and do not constitute an undue limitation of the present invention. In the accompanying drawings:

[0021] Figure 1 It shows a schematic structural diagram of an embodiment of a membrane oxygenator according to the present invention in working condition 2;

[0022] Figure 2 It shows a schematic structural diagram of an embodiment of a membrane oxygenator according to the present invention in working condition 1;

[0023] Figure 3 FIG1 shows a schematic diagram of the flow of blood and gas when the membrane oxygenator according to the present invention is in working condition one;

[0024] Figure 4 FIG. 1 is a schematic diagram showing the flow of blood and gas when the membrane oxygenator according to the present invention is in working condition 2. FIG.

[0025] The above drawings include the following reference numerals:

[0026] 10. Shell; 11. First air cavity; 111. First gas inner cavity; 112. First gas outer cavity; 12. Second air cavity; 13. Gas exchange cavity; 131. Gas exchange inner cavity; 132. Gas exchange outer cavity; 20. Partition; 21. First flow port; 30. Communication port; 40. Blood inlet; 50. Blood outlet; 60. Gas inlet; 70. First gas outlet; 80. Second gas outlet; 90. First sealing member; 100. Second sealing member; 110. Hollow fiber membrane; 120. Blood delivery tube; 130. First support portion; 140. First control valve; 150. Second control valve; 160. Third control valve; 170. Sampling port. DETAILED DESCRIPTION

[0027] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in this application can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0028] It should be noted that the following detailed descriptions are illustrative and intended to provide further explanation of the present application. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which the present application belongs.

[0029] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, they indicate the presence of features, steps, operations, devices, components and / or combinations thereof.

[0030] The present invention provides a membrane oxygenator, please refer to Figures 1 to 4, comprising: a shell 10, the shell 10 having a first air cavity 11, a gas exchange cavity 13, and a second air cavity 12 arranged in sequence along the vertical direction, the gas exchange cavity 13 being connected to the first air cavity 11 and the second air cavity 12; a partition 20 connected to the shell 10, the partition 20 being arranged in the first air cavity 11 and the gas exchange cavity 13 to divide the first air cavity 11 into a first gas inner cavity 111 and a first gas outer cavity 112, and to divide the gas exchange cavity 13 into a gas exchange inner cavity 131 and a gas exchange outer cavity 132; a communication port 30 is provided between the gas exchange inner cavity 131 and the gas exchange outer cavity 132; a blood inlet 40 connected to the gas exchange cavity 1 31; a blood outlet 50 is provided on the shell 10 and is connected to the gas exchange outer cavity 132; the blood outlet 50 and the blood inlet 40 are located on opposite sides of the partition 20 and are both located above the connecting port 30; a gas inlet 60 is provided on the shell 10 and is connected to the first gas outer cavity 112; a first gas outlet 70 is provided on the shell 10 and is connected to the second gas cavity 12; a second gas outlet 80 is provided on the shell 10 and is connected to the first gas inner cavity 111; wherein, a first flow port 21 is provided on the partition 20, and the first flow port 21 is located in the first gas cavity 11; the first flow port 21 is provided to be openable and closable.

[0031] The membrane oxygenator of the present invention includes a partition 20 provided within the housing 10, which divides the first gas chamber 11 into a first gas inner chamber 111 and a first gas outer chamber 112, and also divides the gas exchange chamber 13 into a gas exchange inner chamber 131 and a gas exchange outer chamber 132. During operation, blood enters the gas exchange inner chamber 131 through the blood inlet 40, then enters the gas exchange outer chamber 132 through the communication port 30, and finally exits through the blood outlet 50. The gas passing through the first gas inner chamber 111 can switch its flow direction under the control of the first gas outlet 70, the second gas outlet 80, and the first flow port 21. This arrangement enables the change of gas flow direction, allowing the membrane oxygenator to achieve switchable gas flow direction during use.

[0032] When the first flow port 21 and the first gas outlet 70 are closed and the second gas outlet 80 is open (this is working condition 1), as shown in FIG. Figure 3 As shown, gas enters the first gas outer chamber 112 through the gas inlet 60, then flows through the gas exchange outer chamber 132 and into the second gas chamber 12. The gas entering the second gas chamber 12 flows into the gas exchange inner chamber 131, then into the first gas inner chamber 111, and finally flows out through the second gas outlet 80 provided on the first gas inner chamber 111. In this way, while the gas flow rate remains the same, the gas flow rate is faster, thereby improving the gas exchange efficiency.

[0033] When the first flow port 21 and the first gas outlet 70 are open and the second gas outlet 80 is closed (this is the second working condition), as shown in FIG. Figure 4 As shown, gas enters the first gas outer chamber 112 through the gas inlet 60 and enters the first gas inner chamber 111 through the first flow port 21. At this time, the gas in the first gas outer chamber 112 passes through the gas exchange outer chamber 132 to complete gas exchange with the blood and then enters the second gas chamber 12. The gas in the first gas inner chamber 111 passes through the gas exchange inner chamber 131 to complete gas exchange with the blood and then enters the second gas chamber 12, so that the gas flows out through the first gas outlet 70 provided on the second gas chamber 12. In this way, the blood in the gas exchange inner chamber 131 flows in the same direction as the gas, and the blood in the gas exchange outer chamber 132 flows in the opposite direction to the gas. The blood and gas of the membrane oxygenator first flow in the same direction and then flow in the opposite direction, which improves the gas exchange rate. In addition, in the first working condition, there is a risk of condensed water clogging the gas channel. When the air pressure in the air chamber increases to a certain value due to condensed water clogging the gas channel, it is necessary to switch back to the second working condition and use the top-down airflow to flush the airway and remove the condensed water.

[0034] Specifically, under the condition of the same gas inlet flow rate, the carbon dioxide and oxygen exchange rates between the gas and blood under working conditions one and two are higher than those of the single-chamber membrane oxygenator; among them, the gas exchange rate under working condition one is better than that under working condition two.

[0035] Specifically, the gas introduced through the gas inlet 60 is pure oxygen, air, or a mixed gas of oxygen and air.

[0036] In a specific implementation, the first gas cavity 11 is located above the second gas cavity 12 , the second gas outlet 80 is provided at the top of the housing 10 , and the first gas outlet 70 is provided at the bottom of the housing 10 .

[0037] In this embodiment, the membrane oxygenator further includes a first seal 90 and a second seal 100. Both the first seal 90 and the second seal 100 are disposed within and connected to the housing 10. The first seal 90 and the second seal 100 are spaced apart vertically. The first seal 90 is located above the second seal 100, so that the first seal 90 and the second seal 100 divide the housing 10 into a first air chamber 11, a gas exchange chamber 13, and a second air chamber 12. This arrangement divides the membrane oxygenator into three chambers.

[0038] In this embodiment, the membrane oxygenator further includes a hollow fiber membrane 110. One end of the hollow fiber membrane 110 is connected to the first seal 90 and communicates with the first air cavity 11. The other end of the hollow fiber membrane 110 is connected to the second seal 100 and communicates with the second air cavity 12, so that gas passing through the gas exchange cavity 13 flows within the hollow fiber membrane 110. This arrangement allows gas to move between the first air cavity 11, the gas exchange cavity 13, and the second air cavity 12 through the hollow fiber membrane 110, thereby allowing gas exchange between the gas in the blood and the gas in the hollow fiber membrane 110.

[0039] To transport blood and support the first seal 90, the membrane oxygenator further includes a blood delivery tube 120, which is inserted into and fixedly connected to the housing 10. The blood delivery tube 120 has a first delivery end and a second delivery end oppositely disposed. The first delivery end is located outside the housing 10, the blood inlet 40 is located at the first delivery end, and the second delivery end is connected to the gas exchange lumen 131. The first seal 90 is disposed around the blood delivery tube 120 and between the blood delivery tube 120 and the housing 10.

[0040] In order to support the second sealing member 100 , the membrane oxygenator further includes a first supporting portion 130 connected to the housing 10 . The second sealing member 100 is disposed around the first supporting portion 130 and between the first supporting portion 130 and the housing 10 .

[0041] In this embodiment, the partition 20 is a tubular structure having a first connecting end and a second connecting end. The first connecting end is connected to the top of the shell 10, and the second connecting end extends toward the bottom of the shell 10 and is located in the gas exchange chamber 13; wherein the second connecting end and the bottom of the gas exchange chamber 13 form a connecting port 30.

[0042] In a specific implementation, the partition 20 is a ring-shaped structure.

[0043] In the first embodiment, the first flow opening 21 is an annular opening, which is arranged around the circumference of the partition 20. Such an arrangement allows the gas to enter the first gas inner cavity 111 from the first gas outer cavity 112 more quickly.

[0044] In a specific implementation, the membrane oxygenator further includes an annular valve, which is disposed at the first flow port 21 so that the first flow port 21 can be opened and closed.

[0045] In the second embodiment, there are multiple first flow openings 21, which are spaced apart around the circumference of the partition 20. This arrangement allows gas to flow from the first gas outer cavity 112 into the first gas inner cavity 111 more quickly.

[0046] In a specific implementation, the membrane oxygenator further includes a plurality of first control valves 140 . The plurality of first control valves 140 are provided in a one-to-one correspondence with the plurality of first flow ports 21 , and each first control valve 140 is provided at a corresponding first flow port 21 .

[0047] Preferably, there are two first flow ports 21 , which are arranged opposite to each other along the radial direction of the partition 20 . The membrane oxygenator further includes two first control valves 140 , which are arranged in a one-to-one correspondence with the two first flow ports 21 , and each first control valve 140 is arranged at a corresponding first flow port 21 .

[0048] In this embodiment, the membrane oxygenator further includes: a second control valve 150 disposed on the first gas outlet 70 to control the opening and closing of the first gas outlet 70; and / or a third control valve 160 disposed on the second gas outlet 80 to control the opening and closing of the second gas outlet 80.

[0049] In this embodiment, the membrane oxygenator further includes a sampling port 170, which is provided on the housing 10 and communicates with the gas exchange outer cavity 132. This configuration is used to sample and test the blood that is about to flow out of the membrane oxygenator.

[0050] Specifically, the blood outlet 50 and the sampling port 170 are both provided on the housing and are arranged opposite to each other along the radial direction of the housing; and are both provided close to the first sealing member and at the top of the gas exchange chamber 13 .

[0051] In this embodiment, the shell 10 includes a first shell part, a second shell part and a third shell part, and the first shell part, the third shell part and the second shell part are arranged in sequence from top to bottom; the first shell part forms a first air cavity 11, the second shell part forms a second air cavity 12, and the third shell part forms a gas exchange cavity 13; wherein, the first seal 90, the second seal 100 and the hollow fiber membrane 110 are all arranged in the gas exchange cavity 13.

[0052] In this embodiment, the flow direction of the gas passing through the first gas cavity can be switched by valves (i.e., the first control valve or the annular valve, the second control valve, and the third control valve), and the position of the gas outlet (at the second control valve or the third control valve) changes according to the different gas flow directions. The two first control valves are arranged at two centrally symmetrical locations on the annular partition, or the entirety is an annular valve. In working condition two, the first flow port and the second control valve are opened at the same time, the second control valve is opened as a gas outlet, and the third control valve is closed. The blood and gas flow directions in the gas exchange cavity are the same, and the blood and gas flow directions in the gas exchange outer cavity are opposite. In working condition one, the first flow port and the second control valve are closed at the same time, the third control valve is opened as a gas outlet, and the blood and gas flow directions in the gas exchange cavity and the gas exchange outer cavity are opposite.

[0053] Compared with working condition 2, working condition 1 has a significantly higher gas velocity under the condition of the same gas flow rate, which has a significant positive effect on gas exchange, especially on the exchange efficiency of carbon dioxide. However, in working condition 1, the reverse flow of blood and gas in the gas exchange cavity is more likely to cause the risk of condensed water accumulation blocking the gas channel compared to the unidirectional flow of blood and gas in working condition 2. When the air pressure in the air cavity increases to a certain value due to partial blockage of the hollow fiber membrane, it is necessary to switch back to working condition 2 and use the airflow from top to bottom to flush the airway and take away the condensed water. In theory, the valve provided at the first flow port 21 can also be designed to be passively opened and closed due to changes in the air pressure of the first gas cavity and the first gas outer cavity. For example, in working condition 1, due to the blockage of the airway (hollow fiber membrane), the air pressure of the first gas outer cavity gradually increases to a certain value, prompting the first flow port 21 to passively open, so that the airway in the gas exchange cavity can be automatically flushed.

[0054] Specifically, oxygenators in the prior art are all single-chamber oxygenators, with gas and blood flowing in one direction (co-directionally or counter-directionally). The gas exchange rate in operating condition 2 is better than that of a single-chamber oxygenator. Under operating condition 1, with the same gas flow rate, the gas flow rate is faster, and the gas exchange rate is also better than that of a single-chamber oxygenator.

[0055] From the above description, it can be seen that the above embodiments of the present invention achieve the following technical effects:

[0056] The membrane oxygenator of the present invention includes a partition 20 provided within the housing 10, which divides the first gas chamber 11 into a first gas inner chamber 111 and a first gas outer chamber 112, and also divides the gas exchange chamber 13 into a gas exchange inner chamber 131 and a gas exchange outer chamber 132. During operation, blood enters the gas exchange inner chamber 131 through the blood inlet 40, then enters the gas exchange outer chamber 132 through the communication port 30, and finally exits through the blood outlet 50. The gas passing through the first gas inner chamber 111 can switch its flow direction under the control of the first gas outlet 70, the second gas outlet 80, and the first flow port 21. This arrangement enables the change of gas flow direction, allowing the membrane oxygenator to achieve switchable gas flow direction during use.

[0057] When the first flow port 21 and the first gas outlet 70 are closed and the second gas outlet 80 is open (operating condition 1), gas enters the first gas outer chamber 112 through the gas inlet 60, then flows through the gas exchange outer chamber 132 and into the second gas chamber 12. The gas entering the second gas chamber 12 flows into the gas exchange inner chamber 131, then into the first gas inner chamber 111, and finally flows out through the second gas outlet 80 provided on the first gas inner chamber 111. In this way, while the gas flow rate remains the same, the gas flow rate is faster, thereby improving the gas exchange efficiency.

[0058] When the first flow port 21 and the first gas outlet 70 are open and the second gas outlet 80 is closed (this is operating condition two), gas enters the first gas outer chamber 112 through the gas inlet 60 and enters the first gas inner chamber 111 through the first flow port 21. At this time, the gas in the first gas outer chamber 112 passes through the gas exchange outer chamber 132 to complete gas exchange with the blood before entering the second gas chamber 12. The gas in the first gas inner chamber 111 passes through the gas exchange inner chamber 131 to complete gas exchange with the blood before entering the second gas chamber 12, so that the gas flows out through the first gas outlet 70 provided on the second gas chamber 12. In this way, the blood in the gas exchange inner chamber 131 flows in the same direction as the gas, while the blood in the gas exchange outer chamber 132 flows in the opposite direction. The blood and gas in this membrane oxygenator first flow in the same direction and then in the opposite direction, improving the gas exchange rate. In addition, under working condition 1, there is a risk of condensed water accumulating and blocking the gas passage. When the air pressure in the air cavity increases to a certain value due to condensed water blocking the gas passage, it is necessary to switch back to working condition 2 and use the airflow from top to bottom to flush the air passage and remove the condensed water.

[0059] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchangeable where appropriate, so that the embodiments of the present application described herein can, for example, be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device comprising a series of steps or units is not necessarily limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0060] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used herein to describe the spatial positional relationship of a device or feature to other devices or features as shown in the figures. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figures. For example, if the device in the drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.

[0061] The foregoing description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Those skilled in the art will readily appreciate that various modifications and variations of the present invention are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present invention are intended to be within the scope of protection of the present invention.

Claims

1. A membrane oxygenator, characterized in that: include: A housing (10), the housing (10) comprising a first air cavity (11), a gas exchange cavity (13), and a second air cavity (12) arranged in sequence along a vertical direction, the gas exchange cavity (13) being in communication with both the first air cavity (11) and the second air cavity (12); a partition (20) connected to the housing (10), the partition (20) being arranged in the first gas cavity (11) and the gas exchange cavity (13) to divide the first gas cavity (11) into a first gas inner cavity (111) and a first gas outer cavity (112), and to divide the gas exchange cavity (13) into a gas exchange inner cavity (131) and a gas exchange outer cavity (132); a communication port (30) being provided between the gas exchange inner cavity (131) and the gas exchange outer cavity (132); a blood inlet (40) communicating with the gas exchange lumen (131); a blood outlet (50) disposed on the housing (10) and communicating with the gas exchange outer cavity (132); the blood outlet (50) and the blood inlet (40) are located on opposite sides of the partition (20) and are both located above the communication port (30); a gas inlet (60) disposed on the housing (10) and communicating with the first gas outer cavity (112); a first gas outlet (70) provided on the housing (10) and communicating with the second gas cavity (12); a second gas outlet (80), provided on the housing (10) and communicating with the first gas inner cavity (111); The partition (20) is provided with a first flow port (21), and the first flow port (21) is located in the first air cavity (11); the membrane oxygenator further comprises an annular valve, and the annular valve is provided at the first flow port (21) so that the first flow port (21) can be opened and closed, and the first flow port (21) is an annular port, and the annular port is provided around the circumference of the partition (20); There are a plurality of first flow ports (21), and the membrane oxygenator further comprises a plurality of first control valves (140), wherein the plurality of first control valves (140) are arranged in a one-to-one correspondence with the plurality of first flow ports (21), and each first control valve (140) is arranged at a corresponding first flow port (21); The membrane oxygenator further includes a second control valve (150) disposed on the first gas outlet (70) to control the opening and closing of the first gas outlet (70); and / or a third control valve (160) disposed on the second gas outlet (80) to control the opening and closing of the second gas outlet (80).

2. The membrane oxygenator according to claim 1, characterized in that The membrane oxygenator further comprises a first seal (90) and a second seal (100), wherein the first seal (90) and the second seal (100) are both arranged in the housing (10) and are both connected to the housing (10), and the first seal (90) and the second seal (100) are spaced apart in a vertical direction; the first seal (90) is located above the second seal (100), so that the first seal (90) and the second seal (100) separate the housing (10) into the first air cavity (11), the gas exchange cavity (13) and the second air cavity (12).

3. The membrane oxygenator according to claim 2, characterized in that The membrane oxygenator further comprises: A hollow fiber membrane (110), one end of the hollow fiber membrane (110) is connected to the first sealing member (90) and communicates with the first air cavity (11), and the other end of the hollow fiber membrane (110) is connected to the second sealing member (100) and communicates with the second air cavity (12), so that the gas passing through the gas exchange cavity (13) flows in the hollow fiber membrane (110).

4. The membrane oxygenator according to claim 2, characterized in that The membrane oxygenator further comprises: a blood delivery tube (120), the blood delivery tube (120) being inserted into the housing (10), the blood delivery tube (120) having a first delivery end and a second delivery end arranged opposite to each other, the first delivery end being located outside the housing (10), the blood inlet (40) being located at the first delivery end, and the second delivery end being in communication with the gas exchange lumen (131); The first sealing member (90) is arranged around the blood delivery tube (120) and between the blood delivery tube (120) and the housing (10).

5. The membrane oxygenator according to claim 2, characterized in that: The membrane oxygenator further comprises: The first support portion (130) is connected to the housing (10), and the second sealing member (100) is arranged around the first support portion (130) and between the first support portion (130) and the housing (10).

6. The membrane oxygenator according to any one of claims 1 to 5, characterized in that The partition (20) is a tubular structure having a first connecting end and a second connecting end, the first connecting end being connected to the top of the shell (10), and the second connecting end extending toward the bottom of the shell (10) and being located in the gas exchange chamber (13); The second connection end and the bottom of the gas exchange chamber (13) form the communication port (30).

7. The membrane oxygenator according to claim 6, characterized in that A plurality of the first flow openings (21) are arranged at intervals around the circumference of the partition (20).

8. The membrane oxygenator according to claim 3, characterized in that The housing (10) comprises a first housing portion, a second housing portion and a third housing portion, wherein the first housing portion, the third housing portion and the second housing portion are arranged in sequence from top to bottom; the first housing portion forms the first air cavity (11), the second housing portion forms the second air cavity (12), and the third housing portion forms the gas exchange cavity (13); The first sealing member (90), the second sealing member (100) and the hollow fiber membrane (110) are all arranged in the gas exchange chamber (13).

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