Sample analysis system

Abstract

The present application relates to a sample analysis system, comprising: at least two specific protein analyzers, a sample transfer device, and a control device. The sample transfer device includes: a transfer mechanism having a transfer channel and at least two feeding mechanisms having detection channels. Each specific protein analyzer corresponds to one feeding mechanism, and the detection area of each specific protein analyzer corresponds to the detection channel of its corresponding feeding mechanism. The control device is used to control the sample transfer device to transfer the test sample rack with the sample container to be subjected to specific protein detection to one of the specific protein analyzers. The sample analysis system selects one specific protein analyzer from at least two specific protein analyzers to detect the test sample rack that currently needs to be subjected to specific protein detection, can reasonably allocate the test sample racks, can reduce the speed requirement for the specific protein measurement module, meet the measurement requirements for a large sample volume, and improve the specific protein measurement efficiency.

Description

Technical Field

[0001] This application relates to the field of medical diagnostic devices, and particularly to a sample analysis system. Background Art

[0002] CRP (C-reactive protein) is an acute-phase reaction protein. Under normal circumstances, it exists in human body fluids in small amounts and increases to varying degrees in infectious diseases, having important clinical application value. Especially in recent years, with the rapid development of point-of-care rapid testing technology, the application of CRP in clinical infectious diseases has become more extensive and has once again become the focus of clinical research.

[0003] Blood routine is one of the three routine examinations and is also one of the commonly used auxiliary examination methods for doctors to diagnose diseases. Doctors assist in judging the physical condition by observing the changes in the number of blood cells and their morphological distribution. There is a high correlation between the CRP test results and the blood routine test results. And due to characteristics such as simple operation, fast detection speed, and small amount of specimen required for CRP detection, it is often used by doctors in combination with blood routine for the differentiation between bacterial infection and viral infection.

[0004] Existing sample analysis systems integrate the measurement functions of blood routine and CRP, but usually consist of a set of detection equipment, multiple blood routine measurement pools, and multiple CRP measurement pools. Due to instrument cost and volume limitations, the number of blood routine measurement pools and CRP measurement pools is small, and there is only one set of detection equipment, which greatly limits the measurement speed of blood routine and CRP. Clinically, basically all samples need to be tested for blood routine, while CRP, as an inflammation detection item, only accounts for a certain proportion. Therefore, a high-throughput and efficient blood routine measurement device is needed clinically, along with a high-speed CRP measurement instrument for combined use with blood routine and CRP tests. Summary of the Invention

[0005] To solve the above technical problems, this application provides a sample analysis system.

[0006] The first aspect of the present application provides a sample analysis system, including: at least two specific protein analyzers for specific protein detection, a sample transfer device, and a control device. Among them, the sample transfer device includes: a transfer mechanism having a transfer channel and at least two feeding mechanisms having detection channels. The transfer mechanism is used to transfer a sample rack with a sample container placed therein in the transfer channel. Each feeding mechanism is arranged at intervals along the transfer direction of the transfer channel. The feeding mechanism can transfer the sample rack from the transfer channel to the detection channel and can also transfer the sample rack from the detection channel to the transfer channel; each of the specific protein analyzers corresponds to one of the feeding mechanisms, and the detection area of each specific protein analyzer corresponds to the detection channel of its corresponding feeding mechanism; the at least two specific protein analyzers are configured to detect at least one same specific protein; the control device is electrically connected to each of the specific protein analyzers and the sample transfer device and is configured to: obtain the operating status information of each specific protein analyzer and the measurement mode information of the sample container on the to-be-tested sample rack. When the measurement mode information indicates that there is a sample container that needs to be subjected to specific protein detection placed on the to-be-tested sample rack, control the sample transfer device to transfer the to-be-tested sample rack to the detection area of one of the at least two specific protein analyzers according to the operating status information.

[0007] Optionally, the operating status information includes the detection load information of each specific protein analyzer; the control device is used to control the sample transfer device to transfer the to-be-tested sample rack to the detection area of the specific protein analyzer with a smaller detection load among the at least two specific protein analyzers according to the detection load information of each specific protein analyzer.

[0008] Optionally, the control device is further used to: determine the waiting duration of the to-be-tested sample rack according to the detection load information of each specific protein analyzer and control the sample transfer device to transfer the to-be-tested sample rack to the detection area of the specific protein analyzer with a smaller detection load among the at least two specific protein analyzers after the waiting duration has passed.

[0009] Optionally, the sample analysis system further includes an unloading platform and other analyzers different from the at least two specific protein analyzers. The control device is further used to: when the waiting duration is greater than a preset duration, control the sample transfer device to transfer the to-be-tested sample rack to the unloading platform or other analyzers.

[0010] Optionally, the sample analyzer system further includes at least one hematology analyzer for blood routine detection. Each hematology analyzer corresponds to one of the feeding mechanisms, and the detection area of each hematology analyzer corresponds to the detection channel of its corresponding feeding mechanism.

[0011] Optionally, in the transport direction along the transport channel, the at least one hematology analyzer is located in front of the at least two specific protein analyzers.

[0012] Optionally, the at least one hematology analyzer includes a scanning device for obtaining measurement mode information of the sample container on the test sample rack; the control device is configured to control the sample transfer device to transfer the test sample rack to one of the hematology analyzers for a first complete blood count test and obtain the measurement mode information of the sample container on the test sample rack, and when the measurement mode information indicates that there is a sample container on the test sample rack that needs to be subjected to specific protein detection, control the sample transfer device to transfer the test sample rack that has undergone the first complete blood count test to the detection area of one of the at least two specific protein analyzers according to the operating state information.

[0013] Optionally, each of the at least two specific protein analyzers includes a scanning device for confirming the measurement mode information of the sample container on the test sample rack.

[0014] Optionally, the sample analysis system further includes a loading platform and a platform loading mechanism. The loading platform is located in front of the at least one hematology analyzer in the transport direction along the transport channel and is used for placing the test sample rack, and the platform loading mechanism is used to transfer the sample rack on the loading platform to the transport channel; a scanning device is provided on the loading platform for identifying the sample rack and the identification of the sample placed on the loading platform, and establishing and storing the correspondence between the identification of the sample and its position on the sample rack.

[0015] Optionally, the control device is electrically connected to each of the hematology analyzers and is configured to obtain the complete blood count test data of each of the hematology analyzers; the control device is further configured to determine the sample containers whose complete blood count test data meet the preset recheck conditions as recheck sample containers, and determine one of the at least one hematology analyzer as the recheck hematology analyzer for rechecking the recheck sample containers.

[0016] Optionally, when the test sample rack includes recheck sample containers and sample containers that need to be subjected to specific protein detection, the control device controls the sample transfer device to first transfer the test sample rack that has undergone the first complete blood count test to the recheck hematology analyzer for a complete blood count recheck, and then after the complete blood count recheck of the recheck sample containers on the test sample rack, control the sample transfer device to transfer the rechecked test sample rack to the detection area of one of the at least two specific protein analyzers for specific protein detection.

[0017] Optionally, when the sample rack to be tested includes a retest sample container and a sample container for specific protein detection, the control device is configured to control the sample transfer device to first move the sample rack to be tested that has undergone a first complete blood count test to the detection area of one of the at least two specific protein analyzers for specific protein detection, and then transfer the sample rack to be tested that has undergone specific protein detection to the retest hematology analyzer for a retest of the complete blood count.

[0018] Optionally, the sample analyzer system includes at least two hematology analyzers for complete blood count testing; in the transmission direction along the transmission channel, at least one of the at least two hematology analyzers is located in front of the at least two specific protein analyzers.

[0019] Optionally, the at least two hematology analyzers include: at least one high - end hematology analyzer and at least one low - end hematology analyzer, and the detection items of the high - end hematology analyzer are different from those of the low - end hematology analyzer; in the transmission direction along the transmission channel, the low - end hematology analyzer is located in front of the high - end hematology analyzer.

[0020] Optionally, the control device is further configured to: be electrically connected to each hematology analyzer and configured to obtain the complete blood count test data of each hematology analyzer; determine the sample containers whose complete blood count test data meet the preset retest conditions as retest sample containers and determine the retest modes of the retest sample containers, where the retest modes include the same - item retest mode and the additional - item retest mode; when the sample rack to be tested includes a retest sample container with a retest mode of the same - item retest mode, control the sample transfer device to transfer the sample rack to be tested to the hematology analyzer that performed the first complete blood count test on the retest sample container for retesting; when the sample rack to be tested includes a retest sample container with a retest mode of the additional - item retest mode, control the sample transfer device to transfer the sample rack to be tested to the high - end hematology analyzer for retesting.

[0021] Optionally, in the transmission direction along the transmission channel, at least one of the at least two specific protein analyzers is located between the low - end hematology analyzer and the high - end hematology analyzer; the control device is configured to, when the sample rack to be tested includes a retest sample container with a retest mode of the additional - item retest mode and a sample container for specific protein detection, control the sample transfer device to transport the sample rack to be tested to the specific protein analyzer located between the low - end hematology analyzer and the high - end hematology analyzer, and after the specific protein detection is completed, control the sample transfer device to transfer the sample rack to be tested to the high - end hematology analyzer for retesting.

[0022] Optionally, the at least two specific protein analyzers are selected from a C-reactive protein analyzer, a serum amyloid A analyzer, a procalcitonin analyzer, or other specific protein analyzers, or include an all-in-one machine of two or more of them.

[0023] The second aspect of the present application provides a sample analysis system, including: a specific protein analyzer for specific protein detection, a sample transfer device, a control device, and at least two hematology analyzers for blood routine detection. Among them, the sample transfer device includes: a transfer mechanism with a transfer channel and at least three feeding mechanisms with detection channels. The transfer mechanism is used to transfer a sample rack with a sample container placed thereon in the transfer channel. Each feeding mechanism is arranged at intervals along the transfer direction of the transfer channel. The feeding mechanism can transfer the sample rack from the transfer channel to the detection channel and can transfer the sample rack from the detection channel to the transfer channel; the specific protein analyzer and each hematology analyzer correspond to one of the feeding mechanisms, and the detection areas of the specific protein analyzer and each hematology analyzer respectively correspond to the detection channels of their corresponding feeding mechanisms; along the transfer direction of the transfer channel, the specific protein analyzer is located between the at least two hematology analyzers; the control device is electrically connected to the sample transfer device and is configured to: obtain the measurement mode information of the sample container on the sample rack to be tested, and control the sample transfer device to transfer the sample rack to be tested loaded with a sample to the specific protein analyzer and / or any one of the hematology analyzers for corresponding detection according to the measurement mode information.

[0024] Optionally, the control device is electrically connected to each hematology analyzer and is configured to obtain the blood routine detection data of each hematology analyzer;

[0025] The control device is further configured to determine the sample container whose blood routine detection data meets the preset recheck condition as a recheck sample container, and determine one of the at least two hematology analyzers as a recheck hematology analyzer for rechecking the recheck sample container.

[0026] Optionally, when the sample rack to be tested includes a recheck sample container and a sample container for specific protein detection, the control device controls the sample transfer device to first transfer the sample rack to be tested to the recheck hematology analyzer for blood routine recheck, and then controls the sample transfer device to transfer the rechecked sample rack to be tested to the detection area of the specific protein analyzer for specific protein detection after the blood routine recheck of the recheck sample container on the sample rack to be tested.

[0027] Optionally, when the sample rack to be tested includes a recheck sample container and a sample container for specific protein detection, the control device is configured to control the sample transfer device to first move the sample rack to be tested to the detection area of the specific protein analyzer for specific protein detection, and then transfer the sample rack to be tested that has undergone specific protein detection to the recheck hematology analyzer for blood routine recheck.

[0028] Optionally, the at least two hematology analyzers include: at least one high - end hematology analyzer and at least one low - end hematology analyzer, and the detection items of the high - end hematology analyzer are different from those of the low - end hematology analyzer; in the transmission direction along the transmission channel, the low - end hematology analyzer is located in front of the high - end hematology analyzer.

[0029] Optionally, the control device is further configured to: be electrically connected to each of the hematology analyzers and configured to obtain the blood routine test data of each of the hematology analyzers; determine the sample containers whose blood routine test data meet the preset recheck conditions as recheck sample containers and determine the recheck modes of the recheck sample containers, where the recheck modes include the same - item recheck mode and the additional - item recheck mode; when the sample rack to be tested includes a recheck sample container with a recheck mode of the same - item recheck mode, control the sample transfer device to transfer the sample rack to be tested to the hematology analyzer that performed the first blood routine test on the recheck sample container for recheck; when the sample rack to be tested includes a recheck sample container with a recheck mode of the additional - item recheck mode, control the sample transfer device to transfer the sample rack to be tested to the high - end hematology analyzer for recheck.

[0030] Optionally, in the transmission direction along the transmission channel, the specific protein analyzer is located behind the low - end hematology analyzer and in front of the high - end hematology analyzer; the control device is configured to, when the sample rack to be tested includes a recheck sample container with a recheck mode of the additional - item recheck mode and a sample container for specific protein detection, control the sample transfer device to transport the sample rack to be tested to the specific protein analyzer, and after the specific protein detection is completed, control the sample transfer device to transfer the sample rack to be tested to the high - end hematology analyzer for recheck.

[0031] The above - mentioned technical solution provided by the embodiments of the present application has the following advantages compared with the prior art: The sample analysis system can select one specific protein analyzer from at least two specific protein analyzers to detect the sample rack to be tested that currently needs specific protein detection. Thus, when there are multiple sample racks to be tested that need specific protein detection, the sample racks to be tested can be reasonably allocated, the speed requirement for the specific protein measurement module can be reduced, the measurement demand for a large sample volume can be met, and the specific protein measurement efficiency can be improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] The drawings herein are incorporated into and constitute a part of this specification, showing embodiments in accordance with the present invention and, together with the specification, are used to explain the principles of the present invention.

[0033] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, for those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0034] Figures 1 to 7 Schematic structural diagram of a sample analysis system provided for different embodiments of the present application;

[0035] Figure 8 Schematic structural diagram of a control device provided for an embodiment of the present application. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0036] To make the objectives, technical solutions, and advantages of the embodiments of the present application clearer, the following will clearly and completely describe the technical solutions in the embodiments of the present application with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are some but not all of the embodiments of the present application. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present application without creative efforts fall within the scope of protection of the present application.

[0037] Figure 1 Schematic diagram of a sample analysis system provided for an embodiment of the present application.

[0038] As Figure 1 shown, the sample analysis system includes: at least two specific protein analyzers for specific protein detection (including in the figure: a first specific protein analyzer 10 and a second specific protein analyzer 20), a sample transfer device, and a control device 30.

[0039] In the embodiments of the present application, the at least two specific protein analyzers are configured to detect at least one same specific protein. The at least two specific protein analyzers are selected from C-reactive protein (CRP) analyzers, serum amyloid A (SAA) analyzers, procalcitonin (PCT) analyzers or other specific protein analyzers, or an all-in-one machine including two or more of the above analyzers. For example, the at least two specific protein analyzers are all analyzers that can only detect CRP, or all all-in-one machines that can detect CRP and / or SAA, or one of the specific protein analyzers is an analyzer that can only detect CRP, and the other specific protein analyzer is an all-in-one machine that can detect CRP and / or SAA.

[0040] The function of the sample transfer device is to transfer the sample rack on which the sample container is placed. In the embodiments of the present application, the sample transfer device includes: a transmission mechanism 41 and at least two feeding mechanisms 42 having detection channels.

[0041] A transmission channel is formed in the transmission mechanism 41, and the sample rack can be driven by the transmission mechanism 41 to move in the transmission channel. The feeding mechanism 42 is arranged on the side of the transmission channel, and the feeding mechanisms 42 are arranged at intervals along the transmission direction X of the transmission channel, and there is an interval between adjacent feeding mechanisms 42. The feeding mechanism 42 is used to transfer the sample rack from the transmission channel to the detection channel and transfer the sample rack from the detection channel to the transmission channel.

[0042] In specific applications, the transmission mechanism 41 can adopt any one or a combination of a chain mechanism, a caterpillar mechanism, a belt mechanism, a roller mechanism, and a track mechanism. When multiple combinations are adopted, the transmission mechanism 41 can be matched with multiple different styles of mechanisms arranged along the transmission channel.

[0043] In the embodiments of the present application, the transmission mechanism 41 only needs to be able to complete the transfer of the sample rack, and the shape of the transmission channel is not limited. For example: the transmission channel can be linear, or a broken line with a certain angle, or an arc with a certain curvature, or even an irregular shape is acceptable.

[0044] In the embodiments of the present application, the transmission channel may be a planar channel. For example, the upper surface of the belt of a belt-type mechanism directly serves as the transmission channel. Additionally, considering that the sample rack may fall or its position may twist during transfer, the transmission channel may also be a semi-enclosed channel. For example, baffles are provided on both sides of the belt of the belt-type mechanism, and the top of the baffles is not closed. In this way, a semi-enclosed transmission channel is formed in the area surrounded by the baffles, and the sample rack is restricted by the baffles and will not fall or its position will not twist. Furthermore, considering that when the sample rack is transferred, the sample containers may be randomly placed after being taken by hand, the transmission channel can also be set as a fully enclosed channel. For example, baffles are provided on both sides and the top of the belt of the belt-type mechanism. In this way, when the sample rack is transferred in the transmission channel, the operator cannot take the sample rack, thereby avoiding manual intervention.

[0045] In the embodiments of the present application, the transmission channel serves as the main channel, and each detection channel serves as a sub-channel. During operation, the transmission mechanism 41 can transfer the sample rack to the position of each feeding mechanism 42 on the transmission channel, and then the feeding mechanism 42 transfers the sample rack from the transmission channel to their respective corresponding detection channels, and the feeding structure 42 can also transfer the sample rack back from the detection channel to the transmission channel.

[0046] Each specific protein analyzer can be correspondingly provided with a feeding mechanism 42, and the detection channel of each feeding mechanism 42 corresponds to the position of the detection area of the corresponding specific protein analyzer. For example, the positions of the detection channel and the detection area coincide. This can ensure that when the sample rack moves in the detection channel, the sample rack can move to the detection area of the specific protein analyzer, and thus the sample in the sample container on the sample rack can be collected by the specific protein analyzer for sample detection and analysis.

[0047] In the embodiments of the present application, the feeding mechanism 42 can also adopt any one or a combination of a chain-type mechanism, a caterpillar-type mechanism, a belt-type mechanism, a roller-type mechanism, and a track-type mechanism. When multiple combinations are adopted, the feeding mechanism 42 can be provided with multiple sections of different styles of mechanisms in cooperation. For the description of the feeding mechanism 42, reference can be made in detail to the foregoing description of the transmission mechanism 41. It will not be elaborated here.

[0048] In the embodiments of the present application, the first specific protein analyzer 10 (such as a CRP analyzer capable of detecting C-reactive protein) and the second specific protein analyzer (such as a CRP analyzer capable of detecting C-reactive protein) 20 respectively correspond to a feeding mechanism 42, and the detection areas of the first specific protein analyzer 10 and the second specific protein analyzer 20 correspond to the detection channels of their corresponding feeding mechanisms 42, so that the samples in the sample containers on the sample rack can be subjected to specific protein analysis in the first specific protein analyzer 10 or the second specific protein analyzer 20. In other embodiments, multiple specific protein analyzers can also correspond to the same feeding mechanism, and the detection areas of the multiple specific protein analyzers are arranged along the detection channel of the same feeding mechanism.

[0049] The first specific protein analyzer 10 and the second specific protein analyzer 20 are used to detect the specific proteins of the samples in the sample containers on the sample rack transferred to their corresponding detection channels by the sample transfer device.

[0050] As Figure 1 shown, in the embodiments of the present application, along the transmission direction X of the transmission channel, the first specific protein analyzer 10 is located in front of the second specific protein analyzer 20. In some embodiments, the positions of the first specific protein analyzer 10 and the second specific protein analyzer 20 are not limited, and the front-back order can be freely set.

[0051] In the embodiments of the present application, both "front" and "back" are relative concepts. Among them, "front" refers to the position that is passed first along the transmission direction X, and "back" refers to the position that is passed later along the transmission direction X. Furthermore, the first specific protein analyzer 10 is located in front of the second specific protein analyzer 20, that is, the sample rack on the transmission channel first passes through the first specific protein analyzer 10, and then passes through the second specific protein analyzer 20. Taking Figure 1 the direction shown as an example, the transmission direction X is from right to left, then "front" refers to the relatively right position in the figure, and "back" refers to the relatively left position in the figure. Therefore, the "front" and "back" in the embodiments of the present application describe the relative position relationship between the first specific protein analyzer 10 and the second specific protein analyzer 20, rather than a simple understanding of the literal meaning, and the literal meaning should not constitute a limitation to the present application.

[0052] The control device 30 is electrically connected to the first specific protein analyzer 10, the second specific protein analyzer 20, and the sample transfer device respectively. The control device 30 can be a desktop computer, a laptop computer, a single-chip microcomputer, a PDA, or other devices with computing capabilities. In the embodiment of the present application, the control device 30 is used to obtain the operation status information of each specific protein analyzer and the measurement mode information of the sample containers on the sample rack to be tested. The operation status information refers to the information when the specific protein analyzer is currently performing specific protein detection on the sample. The operation status information at least includes the detection load information of the specific protein analyzer, that is, the number of sample containers to be detected currently assigned to the specific protein analyzer for detection. In other embodiments of the present application, the operation status information may further include machine status information, such as fault information, enable / disable information, etc. The measurement mode information refers to the information of the items to be detected for the samples in each sample container on the sample rack to be tested. Different modes correspond to different detection items. The measurement mode information can be a pre-set mode, and it can be directly received through a cable / wireless method. In addition, the measurement mode can also be obtained by the identification code containing the measurement mode information pasted on the sample containers on the sample rack to be tested. For example, when the sample is transferred on the sample transfer device, the identification code on the sample container is scanned on-site to obtain the measurement mode of the sample to be detected in the sample container.

[0053] When the measurement mode information indicates that there are sample containers on the current sample rack to be tested that need to be subjected to specific protein detection, the control device 30 controls the sample transfer device to transfer the sample rack to be tested to the detection area of at least one of the at least two specific protein analyzers according to the operation status information, so that the sample containers on the sample rack to be tested that need to be subjected to specific protein detection can be subjected to specific protein detection in a suitable specific protein analyzer.

[0054] In the embodiment of the present application, by setting a plurality of specific protein analyzers capable of detecting the same specific protein, the speed requirement for the specific protein measurement module can be reduced, and the measurement requirements for a large sample volume can be met, improving the specific protein measurement efficiency.

[0055] As Figure 1 shown, in some embodiments of the present application, the feeding mechanism 42 in the sample analysis system further includes: a transmission mechanism 421, a loading buffer area 422, and a loading mechanism 423.

[0056] The transmission mechanism 421 can adopt any one or a combination of multiple types of mechanisms such as a chain mechanism, a caterpillar mechanism, a belt mechanism, a roller mechanism, and a track mechanism. When multiple combinations are adopted, the transmission mechanism 421 can be provided with multiple segments of mechanisms with different styles. In the embodiment of the present application, a detection channel is formed in the transmission mechanism 421. And the position of the detection channel corresponds to the position of the detection area of the analyzer corresponding to the feeding mechanism 42, so that the sample container transferred in the detection channel can be smoothly detected.

[0057] As Figure 1 shown, the loading buffer area 422 is located between the detection channel and the transmission channel. The setting of the loading buffer area 422 is mainly considered that if the number of sample racks transferred to the analyzer through the transmission channel is large, and it takes a certain amount of time for the analyzer to complete each sample rack. If all the sample racks on the transmission channel are transferred to the analyzer, the normal analysis and detection will be affected. By setting the loading buffer area 422, the sample racks transferred on the transmission channel can be buffered in this area first, and then, according to the detection speed of the analyzer, the sample racks buffered in this area are transferred to the detection channel in sequence.

[0058] As Figure 1 shown, the loading mechanism 423 is located at the bottom of the loading buffer area 422, and is used to transfer the sample rack passing through the transmission channel to the loading buffer area 422, and to transfer the sample rack in the loading buffer area 422 to the detection channel.

[0059] As Figure 1 shown, the feeding mechanism 42 further includes an unloading buffer area 424 and an unloading mechanism 425. Among them, the unloading buffer area 424 is located between the detection channel and the transmission channel, and the unloading buffer area 424 and the loading buffer area 422 are arranged at intervals along the transmission direction of the detection channel. For example, the loading buffer area 422 and the unloading buffer area 425 are respectively located at both ends of the detection channel. The unloading mechanism 425 is located in the unloading buffer area, and is used to transfer the sample rack passing through the detection channel to the unloading buffer area 424, and to transfer the sample rack in the unloading buffer area 424 to the transmission channel.

[0060] In an embodiment of the present application, the operating state information includes the detection load information of each specific protein analyzer, and the detection load information refers to the number of samples currently assigned to each specific protein analyzer waiting for detection.

[0061] In order to further improve the detection efficiency of specific proteins, when the control device 30 controls the sample transfer device to transfer the sample rack to be tested, the control method can be as follows:

[0062] The control device 30 determines the specific protein analyzer with a smaller detection load according to the detection load information of each specific protein analyzer. Then, the control device 30 controls the sample transfer device to transfer the current sample rack to be tested to the detection area of the specific protein analyzer with a smaller detection load (i.e., relatively idle) among at least two specific protein analyzers.

[0063] This transfer method, which preferentially selects the specific protein analyzer with a smaller detection load, can shorten the detection waiting time of specific proteins on the production line and improve the detection efficiency of specific proteins.

[0064] In an embodiment of the present application, the operating state information may further include machine state information, such as fault information. For example, when one of the specific protein analyzers fails or needs to replace consumables and / or reagents, the specific protein analyzer can be automatically detached from the sample analyzer system, and the control device 30 no longer schedules the sample rack to be tested to it, but schedules the sample rack to another normally operating specific protein analyzer.

[0065] In an embodiment of the present application, when the detection load information of each specific protein analyzer indicates that the corresponding specific protein analyzer is in a busy state (the busy state means that the number of samples waiting for specific protein detection in the specific protein analyzer is greater than the processing capacity of the specific protein analyzer, and the specific protein analyzer needs to work continuously for a period of time before it can be idle), on the one hand, if the sample rack to be tested is still transferred to the specific protein analyzer in the busy state, it will take a relatively long waiting time due to the busy state of the specific protein analyzer; on the other hand, limited by the limited space of the feeding mechanism corresponding to the specific protein analyzer, once the number of sample racks accommodated in the feeding mechanism corresponding to the specific protein analyzer in the busy state is saturated, there will be no extra free position in the feeding mechanism corresponding to the specific protein analyzer in the busy state to accommodate a new sample rack. Therefore, the control device 30 can first determine the waiting time T1 of the sample rack to be tested before being detected according to the detection load information of each specific protein analyzer, and then start timing. When the timing duration t0 = T1, the sample transfer device is controlled to transfer the sample to be tested to the detection area of the specific protein analyzer with a smaller detection load among at least two specific protein analyzers.

[0066] In an embodiment of the present application, the sample analysis system may further include: an unloading platform and other analyzers different from the at least two specific protein analyzers. Among them, the unloading platform can be at the rearmost side in the transfer direction of the transfer device, that is, at the end position in the X direction. The other analyzers can be hematology analyzers, glycosylated hemoglobin analyzers, slide staining machines, etc., and the positions between the other analyzers and the at least two specific protein analyzers can be freely set. For example, as Figure 2As shown, the blood cell analyzer 60 is located in front of the first specific protein analyzer 10 and the second specific protein analyzer 20 along the transport direction of the transport channel, and the slide staining machine 50 is located behind the second specific protein analyzer 20. As Figure 2 shown, the sample analysis system further includes an unloading platform 80 for placing the sample racks. The unloading platform 80 is arranged at one end of the transport channel, and is Figure 2 arranged at the end of the transport direction X of the transport channel. The sample racks on the transport channel can all be transported to the unloading platform 80 for storage.

[0067] In addition, as shown in Figure 2 the figure, the sample analysis system further includes a platform unloading mechanism 81 for transferring the sample racks in the transport channel to the unloading platform 80, and optionally transferring the samples on the unloading platform 80 to the transport channel.

[0068] Considering that the transport channel on the transport mechanism 41 is shared, if the waiting duration T1 of the sample rack to be tested is too long, it may affect the detection speed of the sample containers on the sample rack to be tested that need to be transported to other analyzers for other tests (such as glycosylation or slide making), or cause too many sample racks to be tested waiting to be transported, affecting the efficiency of the sample analyzer system, and even causing traffic jams. For the efficient reuse of the transport channel on the transport mechanism 41, in the embodiment of the present application, after calculating the waiting duration T1, it can be determined whether the waiting duration T1 is greater than a preset duration Tx (the preset duration Tx can be a duration set by the operator himself). When T1 is greater than Tx, the specific protein analyzer of the sample analysis system is still busy. At this time, the control device 30 can control the sample transfer device to transfer the sample rack to be tested to the unloading platform or other analyzers, that is, skip the specific protein detection of the sample rack to be tested, and first unload it to the unloading platform or transport it to other analyzers for measurement.

[0069] Transferring the current sample rack to be tested to the unloading platform or other analyzers can prevent the transfer channel of the transfer device from being occupied, facilitate the transfer of other sample racks to be tested, and improve the transfer efficiency of the transfer channel. For example, when the sample rack to be tested is waiting on the unloading platform, the detection load information of the specific protein analyzer can continue to be monitored. When the specific protein detection conditions are met, the sample rack to be tested is transferred back to the transfer channel from the unloading platform, and then the transfer mechanism 41 transfers the sample rack to the corresponding specific protein analyzer for detection. For example, if the sample in the current sample rack to be tested has other detection items in addition to the specific protein detection, the control device 30 can control the sample transfer device to transfer the current sample rack to other analyzers on the transfer channel. Among them, transferring to other analyzers can facilitate the detection of other detection items for the sample in the sample container on the current sample rack to be tested. Using the waiting time of the current sample rack to be tested for specific protein detection to perform other detection items first can improve the overall detection efficiency of samples with multiple detection items.

[0070] In an embodiment of the present application, the sample analysis system may further include at least one hematology analyzer for blood routine detection, preferably at least two hematology analyzers. Each hematology analyzer corresponds to a feeding mechanism 42, and the detection area of each hematology analyzer corresponds to the detection channel of its corresponding feeding mechanism 42. In some embodiments, in the transmission direction of the transfer channel, at least one hematology analyzer is located in front of at least two specific protein analyzers. As Figure 4 shown in the figure, the figure includes a hematology analyzer 60, and the hematology analyzer 60 is located in front of the first specific protein analyzer 10 in the transmission direction X.

[0071] In an embodiment of the present invention, by providing a plurality of specific protein analyzers and at least one hematology analyzer, the specific protein measurement speed can match the blood routine measurement speed, thereby reducing the risk of traffic jams in the sample analyzer system due to the faster blood routine measurement speed than the specific protein detection speed.

[0072] If the sample analysis system only has at least two specific protein analyzers, that is, the sample analysis system only performs specific protein detection, that is, all sample containers on the sample rack to be tested placed in the sample analysis system need to be subjected to specific protein detection. Therefore, the specific protein analyzer only needs to perform specific protein detection on each sample container transferred to its detection area. If the sample analysis system further includes at least one hematology analyzer, then the sample analysis system will no longer be solely used for specific protein detection and can also perform blood routine detection.

[0073] Therefore, for each sample container in the sample rack to be tested sent into the sample analysis system, its measurement mode needs to be identified. As Figure 2As shown, the sample analysis system generally may further include a loading platform 70 and a platform loading mechanism 71. The loading platform 70 is located at one end of the transmission channel. The loading platform 70 is used to place the sample rack to be tested. The loading platform 70 is located at the front end of the transmission direction X of the transmission channel, that is, the sample rack first moves from the loading platform 70 into the transmission channel and then is transported to each analyzer through the transmission channel respectively. The platform loading mechanism 71 is used to transfer the sample rack on the loading platform 70 to the transmission channel. The sample rack to be tested placed on the loading platform 70 is usually first transported to the hematology analyzer for blood routine testing. For this purpose, in an embodiment of the present application, at least one hematology analyzer includes a scanning device for obtaining the measurement mode information of the sample container on the sample rack to be tested when the sample rack to be tested passes by the hematology analyzer.

[0074] When the measurement mode information indicates that there is a sample container on the sample rack to be tested that needs to be subjected to specific protein detection, the control device 30 controls the sample transfer device to transfer the sample rack to be tested that has undergone blood routine testing, such as the first blood routine testing, to the detection area of one of the at least two specific protein analyzers according to the operation status information.

[0075] That is to say, the sample rack to be tested is first placed on the loading platform 70, the sample rack to be tested on the loading platform 70 is moved to the transmission channel by the platform loading mechanism 71, and then the sample moving device schedules the sample rack to be tested to enter the hematology analyzer for blood routine testing, such as the first blood routine testing. After the blood routine testing is completed, the sample moving device distributes and schedules the sample rack to be tested according to the operation status of multiple specific protein analyzers, for example, preferentially schedules it to enter the idle specific protein analyzer. In some embodiments, when all the specific protein analyzers of the sample analysis system are in a busy state, the sample rack to be tested that has undergone blood routine testing can be temporarily stored in the feeding mechanism of the hematology analyzer and wait until the specific protein analyzer is idle before scheduling.

[0076] Correspondingly, a measurement mode information identifier may be provided on each sample container on the sample rack to be tested. The measurement mode information identifier may be: a normal Chinese character or English letter and other text identifiers or string identifiers. In addition, the measurement mode information identifier may also be a pattern identifier such as a barcode or a two-dimensional code with more information.

[0077] When the sample container passes through the scanning device, the scanning device can obtain the measurement mode information of the sample in the sample container on the sample rack to be tested, and then transmit it to the control device 30 through the hematology analyzer.

[0078] In some embodiments of the present application, the scanning device of the hematology analyzer can identify the sample rack and the sample barcode, and store the correspondence between the sample and its position on the sample rack. The specific protein analyzer can obtain the measurement modes of the samples on the sample rack by identifying the sample rack barcode based on the correspondence between the sample and the sample rack established by the hematology analyzer.

[0079] During the specific detection process, the control device 30 can control the sample transfer device to transfer the sample rack to be tested to the hematology analyzer with a scanning device for the first complete blood count test, and simultaneously obtain the measurement mode information of each sample container on the sample rack to be tested. Then, when the control device 30 analyzes the measurement mode information and indicates that there is a sample container on the sample rack to be tested that needs to be subjected to specific protein detection, the control device 30 controls the sample transfer device to transfer the sample rack to be tested that has undergone the first complete blood count test to the detection area of at least one of the at least two specific protein analyzers according to the operating state information.

[0080] In other embodiments, the scanning device can also be set independently of the hematology analyzer. For example, Figure 3 as shown, the scanning device 101 in the figure can be separately set on the transmission mechanism 41. The position of the scanning device 101 is in front of at least two specific protein analyzers in the transmission direction X, and as Figure 3 shown, the scanning device 101 is directly connected to the control device 30.

[0081] In other embodiments of the present application, a scanning device can also be set on the loading platform 70 to identify the sample rack and the sample barcode placed on the loading platform 70, and establish and store the correspondence between the sample and its position on the sample rack. The hematology analyzer and / or the specific protein analyzer can obtain the measurement modes of the samples on the sample rack by identifying the sample rack barcode based on the correspondence between the sample and the sample rack established by the scanning device on the loading platform 70.

[0082] In other embodiments of the present application, a scanning device can also be provided in each specific protein analyzer. The scanning device provided in the specific protein analyzer is used to re-scan the measurement mode information of the sample container on the sample rack to be tested, so as to confirm whether the sample container on the sample rack to be tested has a specific protein detection mode. The scanning device of the specific protein analyzer can only scan the sample containers that have been confirmed by the scanning device of the hematology analyzer to have a specific protein measurement mode on the sample rack to be tested, and directly skip other sample containers that have been confirmed by the scanning device of the hematology analyzer to have no specific protein mode, so as to improve the measurement efficiency of specific proteins.

[0083] Since the blood routine test data is the basis for medical staff to judge the physical condition of the subject, and when the specific protein analyzer is a whole blood specific protein analyzer that uses whole blood for specific protein detection (such as a whole blood CRP analyzer), it may be necessary to use the blood routine test data to correct the whole blood specific protein test results. Therefore, it is necessary to make the blood routine test data as accurate as possible. In an embodiment of the present application, the control device 30 is electrically connected to each blood cell analyzer. After each blood cell analyzer performs a blood routine analysis, the blood routine test data will be sent to the control device 30.

[0084] The control device 30 will analyze the received blood routine test data. If it is determined that the blood routine test data of a certain sample is problematic, it will also arrange a recheck of the blood routine for this sample.

[0085] Specifically, the control device 30 can determine the sample container whose blood routine test data meets the preset recheck conditions as the recheck sample container, and determine one of at least one blood cell analyzer as the recheck blood cell analyzer for rechecking the recheck sample container.

[0086] After determining the recheck blood cell analyzer, the control device 30 can transfer the recheck sample container to the recheck blood cell analyzer for a blood routine recheck.

[0087] In a specific application, when the sample rack to be tested simultaneously contains a recheck sample container and a sample container for specific protein detection, the control device 30 can control the sample transfer device to first transfer the sample rack to be tested that has undergone the first blood routine test to the recheck blood cell analyzer for a blood routine recheck, and then after the blood routine recheck of the recheck sample container on the sample rack to be tested, control the sample transfer device to transfer the rechecked sample rack to the detection area of at least one of the at least two specific protein analyzers for specific protein detection.

[0088] This method of first giving priority to the blood routine recheck of the sample rack to be tested that simultaneously contains a recheck sample container and a sample container for specific protein detection, and then performing specific protein detection, can enable critical samples that need to be rechecked to complete the blood routine recheck first, and issue a blood routine report in a timely manner on the basis of ensuring quality.

[0089] In the above application scenario, in some embodiments, in the transmission direction along the transmission channel, all blood cell analyzers of the sample analysis system are located in front of the specific protein analyzer, as Figure 5 shown. At this time, it can further ensure that the recheck sample container can be timely rechecked for blood routine, that is, it can ensure that critical values can be timely reported for blood routine under the condition of quality priority.

[0090] In another application, when the sample rack to be tested contains both a retest sample container and a sample container for specific protein detection, the control device 30 can first move the sample rack to be tested that has undergone the first complete blood count test to the detection area of one of the at least two specific protein analyzers for specific protein detection, and then transfer the sample rack to be tested that has undergone specific protein detection to the retest hematology analyzer for a retest of the complete blood count. By giving priority to specific protein detection for the sample rack to be tested that contains both a retest sample container and a sample container for specific protein detection and then performing a retest of the complete blood count, the waiting time for specific protein detection can be reduced, and the specific protein detection report can be issued as early as possible, without being affected by the retest, that is, the specific protein detection efficiency is prioritized.

[0091] In the above application scenario, in some embodiments, along the transmission direction of the transmission channel, the hematology analyzers and specific protein analyzers of the sample analysis system are arranged alternately, as Figure 6 shown. At this time, it can be further ensured that after the samples on the sample rack to be tested have undergone the first complete blood count test, they can be transported to the nearest specific protein analyzer for specific protein detection as soon as possible.

[0092] In some embodiments of the present application, at least two hematology analyzers of the sample analysis system include at least one high - end hematology analyzer and at least one low - end hematology analyzer. The detection items of the high - end hematology analyzer are different from, especially more than and / or superior to, those of the low - end hematology analyzer. The complete blood count test items here are also the complete blood count test parameters. For example, they can include: white blood cell detection (classification and / or counting), red blood cell detection (classification and / or counting), NRBC (Nucleared Red Blood Cell) detection, platelet impedance method detection, platelet optical method detection, reticulocyte detection, blast cell detection, malaria detection, etc. For example, the low - end hematology analyzer is configured to only be able to perform routine white blood cell detection (classification and / or counting), red blood cell detection (classification and / or counting), and platelet impedance method detection, while the high - end hematology analyzer is configured to be able to perform white blood cell detection (classification and / or counting), red blood cell detection (classification and / or counting), NRBC detection, platelet impedance method detection, platelet optical method detection, reticulocyte detection, blast cell detection, malaria detection. When performing a retest of the complete blood count, in one case, the hematology analyzer used for the first complete blood count test can be used for the retest of the complete blood count. In another case, a hematology analyzer different from the one used for the first complete blood count test can also be used for the retest of the complete blood count.

[0093] Generally, if the test items for the follow-up blood routine test are the same as those for the first blood routine test, any hematology analyzer can be selected for the follow-up blood routine test. It is preferably to select the hematology analyzer used for the first blood routine test (the current hematology analyzer) for the follow-up test, that is, preferably to retest with this machine. However, if the test items for the follow-up blood routine test are different from those for the first blood routine test, a hematology analyzer that can perform different test items needs to be selected for the follow-up blood routine test, usually a high-end hematology analyzer.

[0094] For example, the samples on the sample rack to be tested are first subjected to a blood routine test in a low-end hematology analyzer. If the control device 30 determines through analyzing the blood routine test data of the low-end hematology analyzer that some samples on the sample rack to be tested need to undergo a blood routine follow-up test with different test items, the control device 30 can control the sample moving device to transfer the sample rack to be tested to a high-end hematology analyzer for a blood routine follow-up test on the sample containers for follow-up testing.

[0095] In a specific application, considering the pipeline transmission efficiency of the sample rack to be tested in the transmission channel, in the transmission direction along the transmission channel, the low-end hematology analyzer is located in front of the high-end hematology analyzer. This setting method enables the samples on the sample rack to be tested to be sequentially transferred to the high-end hematology analyzer when they need to undergo a blood routine follow-up test with different test items, and directly enter the specific protein analyzer located behind after the blood routine follow-up test.

[0096] Therefore, in an embodiment of the present application, when performing a blood routine follow-up test on a sample, there can be at least two follow-up test modes. The at least two follow-up test modes can include: the same-item follow-up test mode and the additional-item follow-up test mode. Among them, the same-item follow-up test mode means that the test items for the first blood routine test and the blood routine follow-up test are the same, and the additional-item follow-up test mode means that the test items for the first blood routine test are different from those for the blood routine follow-up test. For example, the blood routine follow-up test needs to detect new test items or needs to re-detect the same test items using different test methods. In some embodiments, the same-item follow-up test mode can also be referred to as the original mode follow-up test mode, and the additional-item follow-up test mode can also be referred to as the non-original mode follow-up test mode.

[0097] In a specific application, the control device 30 is further configured to determine the retest mode of the retest sample container according to the blood routine test data. When the retest sample container with the same-item retest mode exists on the to-be-tested sample rack, the control device 30 controls the sample transfer device to transfer the to-be-tested sample rack to the hematology analyzer for the first blood routine test of the retest sample container for retesting; when the retest sample container with the additional-item retest mode exists on the to-be-tested sample rack, the control device 30 controls the sample transfer device to transfer the to-be-tested sample rack to the high-end hematology analyzer for retesting. For example, when the platelet impedance method test result in the blood routine test data indicates an abnormal low platelet value, the optical method needs to be used to retest the platelets to determine whether the result of the abnormal low platelet value in the first blood routine test is accurate.

[0098] Further, for the positional relationship between the hematology analyzer and the specific protein analyzer, it can be set in the following manner:

[0099] At least one of the at least two specific protein analyzers is located between the low-end hematology analyzer and the high-end hematology analyzer.

[0100] In this way, for the control device, when the retest sample container with the additional-item retest mode and the sample container that needs to be subjected to specific protein detection exist on the to-be-tested sample rack, that is, when there are two sample containers that need to be subjected to different tests on the same to-be-tested sample rack, the control sample transfer device first transports the to-be-tested sample rack to the detection area corresponding to the specific protein analyzer located between the low-end hematology analyzer and the high-end hematology analyzer to perform specific protein detection on the sample that needs to be subjected to specific protein detection; then, after the specific protein detection is completed, the control sample transfer device is controlled to transfer the to-be-tested sample rack to the high-end hematology analyzer for retesting.

[0101] With this setting method of the specific protein analyzer and the hematology analyzer, if there are 5 sample containers on the to-be-tested sample rack, and after passing through the low-end hematology analyzer, the samples in 2 sample containers need to be retested with additional items, while the samples in the other 3 sample containers do not need to be retested with additional items, then the samples that do not need to be retested for blood routine can be preferentially subjected to specific protein detection, and then the samples that need to be retested for blood routine can be retested for blood routine. In this way, the samples in the to-be-tested sample rack can quickly obtain specific protein detection, without having to wait for all the samples in the to-be-tested sample rack to be retested for blood routine before specific protein detection can be performed, so the detection waiting time for specific protein can be reduced.

[0102] The embodiment of the present application further provides a sample analysis system, which may include: one specific protein analyzer for specific protein detection, a sample transfer device, a control device 30, and at least two hematology analyzers for blood routine detection. As Figure 7As shown in the figure, the figure includes: a first hematology analyzer 61, a second hematology analyzer 62, and a specific protein analyzer 21 (which can be a CRP analyzer for detecting C-reactive protein).

[0103] The sample transfer device includes: a transfer mechanism 41 having a transfer channel and at least three feeding mechanisms 42 having detection channels. The transfer mechanism 41 is used to transfer a sample rack on which a sample container is placed in the transfer channel. Each feeding mechanism 42 is arranged at intervals along the transfer direction of the transfer channel. The feeding mechanism 42 can transfer the sample rack from the transfer channel to the detection channel and can transfer the sample rack from the detection channel to the transfer channel. For the sample transfer device, reference can be made to the description in Embodiment 1, which will not be elaborated here.

[0104] A feeding mechanism 42 corresponds to each of the specific protein analyzer 21 and each hematology analyzer, and the detection areas of the specific protein analyzer 21, the first hematology analyzer 61, and the second hematology analyzer 62 respectively correspond to the detection channels of their corresponding feeding mechanisms 42; and along the transfer direction of the transfer channel, the specific protein analyzer 21 is located between the first hematology analyzer 61 and the second hematology analyzer 62.

[0105] The control device 30 is electrically connected to the sample transfer device and is configured to obtain the measurement mode information of the sample container on the sample rack to be tested, and control the sample transfer device to transfer the sample rack to be tested loaded with a sample to one or more of the specific protein analyzer 21, the first hematology analyzer 61, and the second hematology analyzer 62 for corresponding detection according to the measurement mode information.

[0106] In the sample analysis system provided by this embodiment of the present application, at least two feeding mechanisms 42 are arranged at intervals on the transfer channel, and one specific protein analyzer and at least two hematology analyzers are arranged along the transfer direction of the transfer channel. For the sample rack to be tested, under the drive of the transfer mechanism 41, on the transfer channel, the control device 30 can control the sample transfer device to transfer the sample rack to be tested loaded with a sample to the specific protein analyzer or any one of the hematology analyzers for corresponding detection, so as to reasonably allocate the sample racks and improve the detection efficiency of the samples.

[0107] Further, since the blood routine test data is the basis for medical staff to judge the physical condition of the subject, and when the specific protein analyzer is a whole blood specific protein analyzer that uses whole blood for specific protein detection, it may be necessary to use the blood routine test data to correct the specific protein detection result of the whole blood. Therefore, it is necessary to make the blood routine test data as accurate as possible. In the embodiment of the present application, the control device 30 is electrically connected to each blood cell analyzer. After each blood cell analyzer performs a blood routine analysis, the blood routine test data will be sent to the control device 30.

[0108] The control device 30 will analyze the received blood routine test data. If it is determined that the blood routine test data of the sample in a certain sample container on the sample rack to be tested meets the preset recheck condition, the control will perform a blood routine recheck on the sample.

[0109] Specifically, the control device 30 can determine the sample container with blood routine test data meeting the preset recheck condition as the recheck sample container, and determine one of at least two blood cell analyzers as the recheck blood cell analyzer for performing a recheck on the recheck sample container. After determining the recheck blood cell analyzer, the control device 30 can transfer the recheck sample container to the recheck blood cell analyzer for a blood routine recheck.

[0110] In a specific application, if the sample rack to be tested simultaneously includes a recheck sample container and a sample container for specific protein detection, the control device 30 can control the sample transfer device to first transfer the sample rack to be tested that has undergone the first blood routine test to the recheck blood cell analyzer for a blood routine recheck, and then after the blood routine recheck of the recheck sample container on the sample rack to be tested, control the sample transfer device to transfer the rechecked sample rack to the detection area of the specific protein analyzer for specific protein detection.

[0111] This way of giving priority to the blood routine recheck of the sample rack to be tested that simultaneously includes a recheck sample container and a sample container for specific protein detection, and then performing specific protein detection, can enable critical samples that need to be rechecked to complete the blood routine recheck first, and issue a blood routine report in a timely manner on the basis of ensuring quality.

[0112] In another application, if the sample rack to be tested simultaneously includes a recheck sample container and a sample container for specific protein detection, the control device 30 can also first move the sample rack to be tested that has undergone the first blood routine test to the detection area of the specific protein analyzer for specific protein detection, and then transfer the sample rack to be tested after specific protein detection to the recheck blood cell analyzer for a blood routine recheck.

[0113] The test sample rack that contains both the re - inspection sample container and the sample container for specific protein detection is preferentially subjected to specific protein detection, and then the blood routine re - inspection is carried out. This can reduce the waiting time for specific protein detection, issue the specific protein detection report as early as possible, and is not affected by the re - inspection, that is, the efficiency of specific protein is given priority.

[0114] In the above - mentioned application scenario, in some embodiments, when carrying out the blood routine re - inspection, in one case, the hematology analyzer used for the first blood routine test can be used for the blood routine re - inspection. In another case, a hematology analyzer different from the first blood routine test can also be used for the blood routine re - inspection.

[0115] Generally, if the test items for the blood routine re - inspection to be carried out are the same as those for the first blood routine test, then any hematology analyzer can be selected for the blood routine re - inspection. It is preferred to select the hematology analyzer (the current hematology analyzer) used for the first blood routine test for re - inspection, that is, preferably re - measure with the same machine. However, if the test items for the blood routine re - inspection to be carried out are different from those for the first blood routine test, then a hematology analyzer that can perform different test items needs to be selected for the blood routine re - inspection, usually a high - configuration hematology analyzer.

[0116] In some embodiments of the present application, at least two hematology analyzers include: at least one high - configuration hematology analyzer and at least one low - configuration hematology analyzer, and the test items of the high - configuration hematology analyzer are different from those of the low - configuration hematology analyzer.

[0117] Furthermore, the samples on the test sample rack are first subjected to blood routine detection in the low - configuration hematology analyzer. If the control device 30 determines through analyzing the blood routine detection data of the low - configuration hematology analyzer that some samples on the test sample rack need to be subjected to blood routine re - inspection with different test items, the control device 30 can control the sample moving device to transfer the test sample rack to the high - configuration hematology analyzer so as to carry out blood routine re - inspection on the re - inspection sample container.

[0118] In a specific application, considering the pipeline transmission efficiency of the sample rack to be tested in the transmission channel, along the transmission direction of the transmission channel, the specific protein analyzer is located behind the low-profile hematology analyzer and in front of the high-profile hematology analyzer. In this way, when the control device 30 has a retest sample container with a retest mode of adding item retest mode and a sample container that needs to be tested for specific proteins on the sample rack to be tested, that is, when there are two sample containers that need to be tested differently on the same sample rack to be tested, the control sample transfer device is controlled to first transport the sample rack to be tested to the detection area corresponding to the specific protein analyzer located between the low-profile hematology analyzer and the high-profile hematology analyzer, and perform specific protein detection on the sample that needs to be tested for specific proteins; then, after the specific protein detection is completed, the control sample transfer device is further controlled to transfer the sample rack to be tested to the high-profile hematology analyzer for retest.

[0119] In some embodiments of the present application, on the basis of Figure 7 , other analyzers can also be provided along the transmission direction of the transmission channel of the transmission mechanism 41, and these all belong to the protection scope of the present application.

[0120] In some embodiments of the present application, as Figure 8 shown, it is a schematic structural diagram of a control device provided by an embodiment of the present application. The control device 30 at least includes: a processing component 31, a RAM 112, a ROM 113, a communication interface 34, a memory 36, and an I / O interface 35. Among them, the processing component 31, the RAM 32, the ROM 33, the communication interface 34, the memory 36, and the I / O interface 35 communicate through a bus 37.

[0121] The processing component can be a CPU, a GPU, or other chips with computing capabilities.

[0122] The memory 36 contains various computer programs such as an operating system and application programs for the processor component 31 to execute, and the data required to execute the computer programs. In addition, during the sample detection process, if there is data that needs to be locally stored, it can all be stored in the memory 36.

[0123] The I / O interface 35 is composed of a serial interface such as USB, IEEE1394 or RS-232C, a parallel interface such as SCSI, IDE or IEEE1284, and an analog signal interface composed of a D / A converter and an A / D converter, etc. An input device composed of a keyboard, a mouse, a touch screen or other control buttons is connected to the I / O interface 35, and the user can directly input data to the control device 30 with the input device. In addition, a display device with a display function, such as a liquid crystal display, a touch screen, an LED display screen, etc., can also be connected to the I / O interface 35. The control device 30 can output the processed data as image display data to the display device for display, such as analysis data, instrument operation parameters, etc.

[0124] The communication interface 34 can be an interface of any communication protocol known currently. The communication interface 34 communicates with the outside through a network. The control device 30 can transmit data with any device connected through the network through the communication interface 34 according to a certain communication protocol.

[0125] It should be noted that in this article, relational terms such as "first" and "second" are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "including a..." does not exclude the existence of additional identical elements in the process, method, article or device including the said element.

[0126] All the features described in the various embodiments, drawings and claims of the specification, as long as they are meaningful within the scope of this application and do not conflict with each other, can be combined arbitrarily.

[0127] The above are only specific embodiments of the present invention, enabling those skilled in the art to understand or implement the present invention. Various modifications to these embodiments will be obvious to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to these embodiments shown herein, but rather to the widest scope consistent with the principles and novel features claimed herein.

Claims

1. A sample analysis system, characterized in that, Comprising: At least two specific protein analyzers, a sample transfer device, and a control device for specific protein detection, wherein, The sample transfer device includes: a transfer mechanism having a transfer channel and at least two feeding mechanisms having detection channels. The transfer mechanism is configured to transfer a sample rack on which a sample container is placed in the transfer channel. Each feeding mechanism is arranged at intervals along the transfer direction of the transfer channel. The feeding mechanism can transfer the sample rack from the transfer channel to the detection channel and can transfer the sample rack from the detection channel to the transfer channel; Each of the specific protein analyzers corresponds to one of the feeding mechanisms, and the detection area of each specific protein analyzer corresponds to the detection channel of its corresponding feeding mechanism; The at least two specific protein analyzers are configured to be able to detect at least one same specific protein; The control device is electrically connected to each of the specific protein analyzers and the sample transfer device and is configured to: obtain the operating state information of each specific protein analyzer and the measurement mode information of the sample container on the to-be-tested sample rack. When the measurement mode information indicates that there is a sample container on the to-be-tested sample rack that needs to be subjected to specific protein detection, control the sample transfer device to transfer the to-be-tested sample rack to the detection area of one of the at least two specific protein analyzers according to the operating state information; The sample analysis system further includes at least one hematology analyzer for hematology detection. Each of the hematology analyzers corresponds to one of the feeding mechanisms, and the detection area of each hematology analyzer corresponds to the detection channel of its corresponding feeding mechanism; In the transfer direction along the transfer channel, the at least one hematology analyzer is located in front of the at least two specific protein analyzers; The to-be-tested sample rack simultaneously contains a re-examination sample container and a sample container that needs to be subjected to specific protein detection. The control device controls the sample transfer device to first transfer the to-be-tested sample rack that has undergone the first hematology detection to the re-examination hematology analyzer for hematology re-examination, and then after the re-examination of the re-examination sample container on the to-be-tested sample rack, control the sample transfer device to transfer the re-examined to-be-tested sample rack to the detection area of one of the at least two specific protein analyzers for specific protein detection.

2. The sample analysis system according to claim 1, wherein The operating state information includes the detection load information of each specific protein analyzer; The control device is configured to control the sample transfer device to transfer the to-be-tested sample rack to the detection area of the specific protein analyzer with a smaller detection load among the at least two specific protein analyzers according to the detection load information of each specific protein analyzer.

3. The sample analysis system according to claim 2, wherein The control device is further configured to: determine the waiting duration of the to-be-tested sample rack according to the detection load information of each specific protein analyzer and control the sample transfer device to transfer the to-be-tested sample rack to the detection area of the specific protein analyzer with a smaller detection load among the at least two specific protein analyzers after the expiration of the waiting duration.

4. The sample analysis system according to claim 3, characterized in that The sample analysis system further includes an unloading platform and other analyzers different from the at least two specific protein analyzers, and the control device is further configured to: when the waiting duration is greater than a preset duration, control the sample transfer device to transfer the test sample rack to the unloading platform or other analyzers.

5. The sample analysis system according to claim 1, wherein The at least one hematology analyzer includes a scanning device for obtaining measurement mode information of a sample container on the test sample rack; The control device is configured to control the sample transfer device to transfer the test sample rack to one of the hematology analyzers for a first complete blood count test and obtain the measurement mode information of the sample container on the test sample rack, and when the measurement mode information indicates that there is a sample container on the test sample rack that needs to be subjected to specific protein detection, control the sample transfer device to transfer the test sample rack that has undergone the first complete blood count test to the detection area of one of the at least two specific protein analyzers according to the operating status information.

6. The sample analysis system according to claim 5, wherein Each of the at least two specific protein analyzers includes a scanning device for confirming the measurement mode information of the sample container on the test sample rack.

7. The sample analysis system according to any one of claims 5 to 6, characterized in that, It further includes a loading platform and a platform loading mechanism. The loading platform is located before the at least one hematology analyzer in the transmission direction along the transmission channel and is used for placing the test sample rack, and the platform loading mechanism is used to transfer the sample rack on the loading platform to the transmission channel; a scanning device is provided on the loading platform for identifying the sample rack and the identification of the sample placed on the loading platform, and establishing and storing the correspondence between the identification of the sample and its position on the sample rack.

8. The sample analysis system according to any one of claims 5 to 6, characterized in that, The control device is electrically connected to each of the hematology analyzers and is configured to obtain the complete blood count test data of each of the hematology analyzers; The control device is further configured to determine a sample container whose complete blood count test data meets the preset recheck condition as a recheck sample container, and determine one of the at least one hematology analyzer as the recheck hematology analyzer for rechecking the recheck sample container.

9. The sample analysis system according to claim 8, characterized in that, When the test sample rack includes a recheck sample container and a sample container that needs to be subjected to specific protein detection, the control device is configured to control the sample transfer device to first transfer the test sample rack that has undergone the first complete blood count test to the recheck hematology analyzer for a complete blood count recheck, and then control the sample transfer device to transfer the rechecked test sample rack to the detection area of one of the at least two specific protein analyzers for specific protein detection after the complete blood count recheck of the recheck sample container on the test sample rack.

10. The sample analysis system according to claim 8, wherein When the test sample rack includes a recheck sample container and a sample container that needs to be subjected to specific protein detection, the control device is configured to control the sample transfer device to first move the test sample rack that has undergone the first complete blood count test to the detection area of one of the at least two specific protein analyzers for specific protein detection, and then transfer the test sample rack that has undergone specific protein detection to the recheck hematology analyzer for a complete blood count recheck.

11. The sample analysis system according to any one of claims 5 to 6, characterized in that, The sample analysis system includes at least two hematology analyzers for complete blood count tests; In the transport direction along the transport channel, at least one of the at least two hematology analyzers is located in front of at least two of the specific protein analyzers.

12. The sample analysis system according to claim 11, wherein, The at least two hematology analyzers include: at least one high - end hematology analyzer and at least one low - end hematology analyzer, and the detection items of the high - end hematology analyzer are different from those of the low - end hematology analyzer; In the transport direction along the transport channel, the low - end hematology analyzer is located in front of the high - end hematology analyzer.

13. The sample analysis system according to claim 12, wherein The control device is further configured to: Be electrically connected to each of the hematology analyzers and configured to obtain the complete blood count test data of each of the hematology analyzers; Determine the sample containers whose complete blood count test data meet the preset re - inspection conditions as re - inspection sample containers and determine the re - inspection modes of the re - inspection sample containers, where the re - inspection modes include the same - item re - inspection mode and the additional - item re - inspection mode; When the test sample rack includes a re - inspection sample container with a re - inspection mode of the same - item re - inspection mode, control the sample transfer device to transfer the test sample rack to the hematology analyzer that performs the first complete blood count test on the re - inspection sample container for re - inspection; When the test sample rack includes a re - inspection sample container with a re - inspection mode of the additional - item re - inspection mode, control the sample transfer device to transfer the test sample rack to the high - end hematology analyzer for re - inspection.

14. The sample analysis system according to claim 13, wherein In the transport direction along the transport channel, at least one of the at least two specific protein analyzers is located between the low - end hematology analyzer and the high - end hematology analyzer; The control device is configured to, when the test sample rack includes a re - inspection sample container with a re - inspection mode of the additional - item re - inspection mode and a sample container that needs to be subjected to specific protein detection, control the sample transfer device to transport the test sample rack to the specific protein analyzer located between the low - end hematology analyzer and the high - end hematology analyzer, and after the specific protein detection is completed, control the sample transfer device to transfer the test sample rack to the high - end hematology analyzer for re - inspection.

15. The sample analysis system according to claim 1, wherein The at least two specific protein analyzers are selected from a C - reactive protein analyzer, a serum amyloid A analyzer, a procalcitonin analyzer or other specific protein analyzers, or include an all - in - one machine of two or more of them.

16. A sample analysis system, characterized in that, Comprising: One specific protein analyzer for specific protein detection, a sample transfer device, a control device and at least two hematology analyzers for complete blood count detection, where The sample transfer device includes: a transport mechanism having a transport channel and at least three feeding mechanisms having detection channels, the transport mechanism is used to transfer the sample rack on which the sample container is placed in the transport channel, each feeding mechanism is arranged at intervals in the transport direction along the transport channel, and the feeding mechanism can transfer the sample rack from the transport channel to the detection channel and can transfer the sample rack from the detection channel to the transport channel; The specific protein analyzer and each of the hematology analyzers each correspond to one of the feeding mechanisms, and the detection areas of the specific protein analyzer and each of the hematology analyzers respectively correspond to the detection channels of their corresponding feeding mechanisms; In the transmission direction along the transmission channel, the specific protein analyzer is located between the at least two hematology analyzers; The control device is electrically connected to the sample transfer device and is configured to: obtain the measurement mode information of the sample container on the test sample rack, and control the sample transfer device to transfer the test sample rack loaded with the sample to the specific protein analyzer and / or any one of the hematology analyzers for corresponding detection according to the measurement mode information; The control device is electrically connected to each of the hematology analyzers and is configured to obtain the blood routine test data of each of the hematology analyzers; The control device is further configured to analyze the received blood routine test data, and when it is determined that the blood routine test data of the sample in a certain sample container on the test sample rack meets the preset recheck condition, determine the sample container with the blood routine test data meeting the preset recheck condition as the recheck sample container, and determine one of the at least two hematology analyzers as the recheck hematology analyzer for rechecking the recheck sample container; When the test sample rack includes a recheck sample container and a sample container that needs to be subjected to specific protein detection, the control device is configured to control the sample transfer device to first transfer the test sample rack to the recheck hematology analyzer for blood routine recheck, and then control the sample transfer device to transfer the rechecked test sample rack to the detection area of the specific protein analyzer for specific protein detection after the blood routine recheck of the recheck sample container on the test sample rack.

17. The sample analysis system according to claim 16, wherein, When the test sample rack includes a recheck sample container and a sample container that needs to be subjected to specific protein detection, the control device is configured to control the sample transfer device to first move the test sample rack to the detection area of the specific protein analyzer for specific protein detection, and then transfer the test sample rack subjected to specific protein detection to the recheck hematology analyzer for blood routine recheck.

18. The sample analysis system according to any one of claims 16 to 17, characterized in that, The at least two hematology analyzers include: at least one high - end hematology analyzer and at least one low - end hematology analyzer, and the detection items of the high - end hematology analyzer are different from those of the low - end hematology analyzer; In the transmission direction along the transmission channel, the low - end hematology analyzer is located in front of the high - end hematology analyzer.

19. The sample analysis system according to claim 18, wherein The control device is further configured to: Be electrically connected to each of the hematology analyzers and be configured to obtain the blood routine test data of each of the hematology analyzers; Determine the sample container with the blood routine test data meeting the preset recheck condition as the recheck sample container and determine the recheck mode of the recheck sample container, and the recheck mode includes the same - item recheck mode and the additional - item recheck mode; When there is a retest sample container with the retest mode being the same-item retest mode on the to-be-tested sample rack, control the sample transfer device to transfer the to-be-tested sample rack to a hematology analyzer for the first complete blood count test on the retest sample container for retest; When there is a retest sample container with the retest mode being the additional-item retest mode on the to-be-tested sample rack, control the sample transfer device to transfer the to-be-tested sample rack to the high-end hematology analyzer for retest.

20. The sample analysis system according to claim 19, wherein, In the transmission direction along the transmission channel, the specific protein analyzer is located behind the low-end hematology analyzer and in front of the high-end hematology analyzer; The control device is used to, when there is a retest sample container with the retest mode being the additional-item retest mode and a sample container for specific protein detection on the to-be-tested sample rack, control the sample transfer device to transport the to-be-tested sample rack to the specific protein analyzer, and after the specific protein detection is completed, control the sample transfer device to transfer the to-be-tested sample rack to the high-end hematology analyzer for retest.

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