A contact lens for detecting ocular health status

Abstract

The application belongs to the field of intelligent sensors. Specifically, a contact lens for detecting eye health status is provided, comprising a contact lens body and an electrochemical impedance spectroscopy analysis module. A flexible sensor is arranged on the contact lens body, which is made in accordance with the shape of the contact lens; the flexible sensor is connected with the electrochemical impedance spectroscopy analysis module; wherein the flexible sensor is used to acquire electrochemical impedance spectroscopy representing eye physiological data; the electrochemical impedance spectroscopy analysis module is used to analyze the electrochemical impedance spectroscopy representing eye physiological data, and obtain the health status of the eye. Based on the technical solution provided in the application, monitoring of the eye health status by using the contact lens can be realized.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of glasses, in particular to a contact lens for detecting eye health status. BACKGROUND

[0002] The contact lens is made of polymer material and is an innovative product in the glasses industry. Compared with traditional frame glasses, the contact lens has better and more natural vision, and can better meet different aesthetic requirements and life needs.

[0003] In recent years, many people work, study and entertain through mobile phones and computers, and have ignored the problem of eye strain caused by long-term staring at electronic screens. Eye strain can cause eye fatigue, dry eye and myopia, and in severe cases, there is a risk of retinal detachment. Therefore, timely monitoring of the health status of the eyes is becoming increasingly important in today's society. SUMMARY

[0004] In view of the above problems of the prior art, the present application provides a contact lens for detecting eye health status, which can timely detect eye health problems through the contact lens.

[0005] To achieve the above purpose, the first aspect of the present application provides a contact lens for detecting eye health status, comprising a contact lens body, a flexible sensor is arranged on the contact lens body, the flexible sensor is made in accordance with the shape of the contact lens; the flexible sensor is connected with an electrochemical impedance spectrum analysis module; wherein the flexible sensor is used to obtain an electrochemical impedance spectrum representing eye physiological data; the electrochemical impedance spectrum analysis module is used to analyze the electrochemical impedance spectrum representing eye physiological data to obtain the health status of the eye.

[0006] From the above, by arranging a flexible sensor on the contact lens, the electrochemical impedance spectrum representing eye physiological data is monitored, and then the electrochemical impedance spectrum analysis module is used to analyze the electrochemical impedance spectrum to obtain the health status of the eye, thereby realizing the monitoring of the eye health.

[0007] As an implementation manner of the first aspect, the flexible sensor comprises: a conductive area, an electrochemical impedance spectrum measurement area and a communication area; the conductive area is used to make both ends of the electrochemical impedance spectrum measurement area conductive; the electrochemical impedance spectrum measurement area is used to obtain an electrochemical impedance spectrum representing eye physiological data; and the communication area is used to realize communication with the electrochemical impedance spectrum analysis module.

[0008] As an implementation manner of the first aspect, the conductive area is obtained by patterning the conductive material through processes such as evaporation, sputtering and inkjet.

[0009] As an implementation form of the first aspect, the electrochemical impedance spectroscopy measurement region comprises: a first resistor, a second resistor and a capacitor; the first resistor is used to characterize the equivalent resistance of the eye solution to be measured; the second resistor is used to characterize the equivalent resistance of the flexible sensor; and the capacitor is used to characterize the equivalent capacitance of the flexible sensor combined with the eye solution to be measured.

[0010] As an implementation form of the first aspect, the communication region comprises: an electrode; the electrode is connected with the electrochemical impedance spectroscopy analysis module through an ultrathin wire with biological compatibility and realizes communication.

[0011] As an implementation form of the first aspect, the communication region comprises: a first coil, which is wound on the contact lens body and connected with the flexible sensor, and realizes wireless communication through coupling induction generated by a second coil in the electrochemical impedance spectroscopy analysis module.

[0012] Therefore, through the above-mentioned flexible sensor, the equivalent resistance in the tear liquid can be measured, so as to obtain the electrochemical impedance spectroscopy for characterizing the eye physiological data. In addition, the electrode led out by the communication region realizes the wired communication between the flexible sensor and the electrochemical impedance spectroscopy analysis module, and the first coil and the second coil are arranged to realize the wireless communication between the flexible sensor and the electrochemical impedance spectroscopy analysis module.

[0013] As an implementation form of the first aspect, the electrochemical impedance spectroscopy analysis module is attached to the skin around the eye.

[0014] As an implementation form of the first aspect, the electrochemical impedance spectroscopy analysis module comprises:

[0015] a frequency generator, an analog-to-digital converter, a central processing unit, a wireless transmission module, a memory and an upper computer module; the frequency generator is used to provide the flexible sensor with a scanning frequency of the electrochemical impedance spectroscopy; the analog-to-digital converter is used to convert the analog signal of the electrochemical impedance collected by the flexible sensor into a digital signal of the electrochemical impedance spectroscopy; the central processing unit is used to send a control instruction to the frequency generator, the analog-to-digital converter, the memory and the wireless transmission module, and the control instruction is used to control the working state of each module; the memory is used to store the digital signal of the electrochemical impedance spectroscopy; the wireless transmission module is used to wirelessly transmit the digital signal of the electrochemical impedance spectroscopy to the upper computer module; and the upper computer module is used to calculate the electrochemical impedance spectroscopy parameter for characterizing the eye health state according to the digital signal of the electrochemical impedance spectroscopy, determine the electrochemical impedance spectroscopy curve for characterizing the eye health state according to the parameter, and display the curve.

[0016] As an implementation form of the first aspect, the electrochemical impedance spectrum analysis module further comprises: a second coil, configured to inductively couple with the first coil in the flexible sensor when the flexible sensor and the electrochemical impedance spectrum analysis module are in wireless communication.

[0017] In summary, the specific structure of the electrochemical impedance spectrum analysis module is provided, and the electrochemical impedance spectrum representing the eye physiological data can be analyzed to obtain the health status of the eye.

[0018] As an implementation form of the first aspect, the flexible sensor is further modified with a sensitive film for detecting a specific index.

[0019] In summary, by modifying the specific antibody on the flexible sensor, specific detection is realized, and the functionality of the contact lens is further enriched.

[0020] These and other aspects of the application will become more fully understood from the following description of (several) embodiments, given by way of example only, and with reference to the accompanying drawings. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 A structural schematic diagram of the contact lens for detecting the health status of the eye according to the embodiments of the application is shown in the figure;

[0022] Figure 2 An equivalent circuit diagram of the electrochemical impedance spectrum detection according to the embodiments of the application is shown in the figure;

[0023] Figure 3 A structural block diagram of the electrochemical impedance spectrum analysis module according to the embodiments of the application is shown in the figure;

[0024] Figure 4 An electrochemical impedance spectrum curve displayed by the host computer according to the embodiments of the application is shown in the figure. DETAILED DESCRIPTION

[0025] The words "first", "second", "third", etc. or module A, module B, module C, etc. in the specification and claims are only used to distinguish similar objects, and do not represent a specific order of the objects. It can be understood that the specific order or sequence can be interchanged as long as it is allowed, so that the embodiments of the application described herein can be implemented in an order other than that illustrated or described herein.

[0026] In the following description, the labels indicating the steps, such as S110, S120, etc., do not necessarily mean that the steps are executed in this order, and the order of the steps can be interchanged or the steps can be executed simultaneously as long as it is allowed.

[0027] The term "comprising" as used in the specification and claims should not be construed as limiting itself to what follows; it does not exclude other elements or steps. Therefore, it should be interpreted as specifying the presence of the mentioned feature, integral, step, or component, but does not exclude the presence or addition of one or more other features, integrals, steps, or components, or groups thereof. Thus, the statement "device comprising means A and B" should not be limited to a device consisting solely of components A and B.

[0028] The terms "an embodiment" or "an embodiment" as used in this specification mean that a particular feature, structure, or characteristic described in conjunction with that embodiment is included in at least one embodiment of this application. Therefore, the terms "in one embodiment" or "in an embodiment" appearing throughout this specification do not necessarily refer to the same embodiment, but may refer to the same embodiment. Furthermore, in one or more embodiments, the particular features, structures, or characteristics can be combined in any suitable manner, as will be apparent to those skilled in the art from this disclosure.

[0029] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. In case of any inconsistency, the meaning set forth in this specification or derived from the content described herein shall prevail. Furthermore, the terminology used herein is for the purpose of describing embodiments of this application only and is not intended to limit the scope of this application.

[0030] To make the objectives, technical solutions, and advantages of this application clearer, the application will now be described in further detail with reference to the accompanying drawings.

[0031] The following describes in detail, with reference to the figures, an embodiment of the present application of a contact lens for detecting eye health.

[0032] like Figure 1 The diagram shown is a schematic representation of a contact lens for detecting eye health, provided in an embodiment of this application. The contact lens includes a lens body 100, a flexible sensor 200, and an electrochemical impedance spectroscopy (EIS) analysis module 300. The flexible sensor 200 is disposed on the lens body 100, and the EIS analysis module 300 is connected to the flexible sensor 200. It should be understood that this connection can be wired or wireless, as long as communication between the two (flexible sensor 200 and EIS analysis module 300) is possible. The flexible sensor 200 is formed into a flexible thin film conforming to the shape of the lens body 100. The flexible sensor 200 is used to acquire electrochemical impedance spectroscopy data characterizing eye physiological data. The EIS analysis module 300 is used to analyze the received electrochemical impedance spectroscopy data characterizing eye physiological data to obtain the eye's health status.

[0033] For example, the equivalent circuit for implementing electrochemical impedance spectroscopy detection in the flexible sensor 200 can be found in [reference needed]. Figure 2 In this equivalent circuit, R s R represents the equivalent resistance of the ocular solution (e.g., tears) being tested. et C represents the equivalent resistance of the flexible sensor 200. dl This represents the equivalent capacitance after the flexible sensor 200 combines with the ocular solution to be tested, where R s R et With C dl The circuits are connected in series. It should be understood that this embodiment does not limit the connection method of the equivalent circuit; it can be any of the following: Figure 2 The series connection can also be parallel, or a hybrid series-parallel connection (not shown). By collecting the above R... s R et And C dl The changes in the tear fluid are analyzed to obtain an electrochemical impedance spectroscopy (EIS) spectrum representing ocular physiological data. For example, glucose in tears can be converted into an EIS spectrum representing ocular physiological data. As an alternative implementation, this equivalent circuit can be fabricated as a sensitive thin film, which is used to measure the EIS of the ocular solution being tested. It should be understood that each sensitive thin film corresponds to a different specific modification, and by detecting these films, biochemical parameters, intraocular pressure, ocular temperature, and ocular blood oxygenation in the ocular solution can be measured.

[0034] It should be understood that the flexible sensor 200 requires conductivity to operate; therefore, the flexible sensor 200 also includes a conductive region for making the equivalent circuit of the electrochemical impedance spectroscopy detection conductive. As an optional implementation, the conductive region can be obtained by patterning a conductive material using processes such as vapor deposition, sputtering, and inkjet printing. The conductive material may include gold, silver, conductive polymers, or other conductive materials. The patterning can represent processing the conductive region into a specific shape; for example, the conductive region can be processed into a thin film, a linear array, or an interdigitated shape.

[0035] Since the flexible sensor 200 needs to communicate with the electrochemical impedance spectroscopy analysis module 300, the flexible sensor 200 further comprises a communication area. As an optional implementation, the communication area can comprise two electrodes which can be connected to the electrochemical impedance spectroscopy analysis module 300 through ultra-thin wires with biological compatibility, so as to realize wired communication with the electrochemical impedance spectroscopy analysis module 300. The communication can also be realized in a wireless manner. As another optional implementation, the communication area can comprise a first coil which is wound on the contact lens body and connected to the flexible sensor 200. As an optional implementation, the first coil is wound at the edge of the contact lens (i.e. away from the pupil), so as not to block the line of sight. Corresponding to the first coil, a second coil is arranged on the side of the electrochemical impedance spectroscopy analysis module 300, and wireless communication between the flexible sensor 200 and the electrochemical impedance spectroscopy analysis module 300 is realized through coupling induction generated by the first coil and the second coil.

[0036] In the embodiment, in order to make the electrochemical impedance spectroscopy analysis module 300 small in size, the size thereof can be set to be between 1x1x0.3cm and 5x5x5cm, and the specific size design can be determined according to the position where the electrochemical impedance spectroscopy analysis module 300 is arranged. As an optional implementation, the electrochemical impedance spectroscopy analysis module 300 can be attached to the skin around the eye. As another optional implementation, a spectacle frame without a lens can be arranged to place the electrochemical impedance spectroscopy analysis module 300. Through such arrangement, the coupling induction intensity between the second coil in the electrochemical impedance spectroscopy analysis module 300 and the first coil in the flexible sensor 200 can be improved.

[0037] In the embodiment, as shown in FIG. 2, the electrochemical impedance spectroscopy analysis module 300 comprises a power supply 301, a signal processing unit 302, a display unit 303, a communication unit 304, a memory unit 305 and a second coil 306. Figure 3As shown, it is a structural block diagram of the electrochemical impedance spectroscopy analysis module. The electrochemical impedance spectroscopy analysis module 300 includes a frequency generator 310, an analog-to-digital converter 320, a central processing unit 330, a wireless transmission module 340, a memory 350 and a memory 350. The frequency generator 310 is used to provide the scanning frequency of the electrochemical impedance spectroscopy for the flexible sensor 200. As an example, the frequency generator 310 can provide an electrical signal with a frequency of 1 Hz-1 MHz and an amplitude of 10 mV-3 V. The analog-to-digital converter 320 is used to convert the analog signal of the electrochemical impedance collected by the flexible sensor 200 into a digital signal of the electrochemical impedance spectroscopy, and transmit the digital signal to the memory 350 through the wireless transmission module 340 for storage, and transmit the digital signal to the host computer module 360. Among them, the transmission mode can include Bluetooth transmission, WIFI transmission or RFID transmission and the like. The host computer module 360 processes and calculates the received digital signal, obtains the electrochemical impedance spectroscopy parameters representing the eye health state and determines the electrochemical impedance spectroscopy curve representing the eye health state according to the parameters, and displays the curve. As shown in the figure, Figure 4 As shown, it is the display screen of the host computer, which includes the electrochemical impedance spectroscopy curve representing the eye health state, and the values of the electrochemical impedance R s , R et and C dl and the scanning frequency value calculated according to the electrochemical impedance spectroscopy curve, wherein the block after each physical quantity displays its corresponding value. Among them, R s represents the equivalent resistance of the eye solution to be measured, R et represents the value of the equivalent resistance of the flexible sensor 200, C dl represents the equivalent capacitance of the combination of the flexible sensor 200 and the eye solution to be measured, f represents the scanning frequency provided by the frequency generator 310, Z' represents the real part of the electrochemical impedance, Z" represents the imaginary part of the electrochemical impedance, and |Z| represents the absolute value of the electrochemical impedance. In this embodiment, a central processing unit 330 is also provided, which is used to send control instructions to the frequency generator 310, the wireless transmission module 340, the memory 350 and the analog-to-digital converter 320. The control instructions are used to control the working state of each module, including its working frequency, working interval, working cycle and the like.

[0038] In this embodiment, the electrochemical impedance spectroscopy analysis module 300 can be compatible with single channel or multiple channel data acquisition. As an optional implementation manner, when the electrochemical impedance spectroscopy analysis module 300 is multiple channels, the data of each two channels can be differentially processed, and then the subsequent electrochemical impedance spectroscopy analysis is performed, so as to improve the data accuracy.

[0039] As an optional implementation, the sensitive film for detecting specific indicators can also be decorated on the flexible sensor 200 to realize specific detection.

[0040] The technical scheme provided by the embodiments of the present application is mainly applied in the detection of eye health status, that is, the medical detection field. The flexible sensor is arranged on the contact lens to monitor the electrochemical impedance spectrum representing the physiological data of the eye, and then the health status of the eye is obtained by analyzing the electrochemical impedance spectrum by using the electrochemical impedance spectrum analysis module, so that the monitoring of the eye health is realized.

[0041] It should be noted that the above are only the preferred embodiments of the present application and the technical principles used. Those skilled in the art will understand that the present application is not limited to the specific embodiments described herein, and those skilled in the art can make various obvious changes, readjustments and substitutions without departing from the scope of the present application. Therefore, although the present application has been described in more detail through the above embodiments, the present application is not limited to the above embodiments, and more other equivalent embodiments can be included without departing from the concept of the present application, and all belong to the protection scope of the present application.

Claims

1. A contact lens for detecting an ocular health condition, comprising a contact lens body, characterized in that, The flexible sensor is made according to the shape of the contact lens body; The flexible sensor is connected with an electrochemical impedance spectrum analysis module; wherein the flexible sensor is used to acquire an electrochemical impedance spectrum representing eye physiological data; and the electrochemical impedance spectrum analysis module is used to analyze the electrochemical impedance spectrum representing eye physiological data to obtain the health status of the eye; The flexible sensor comprises an electrochemical impedance spectrum measurement region, which comprises: a first resistor, a second resistor and a capacitor; the first resistor is used to represent the equivalent resistance of the eye solution to be measured; the second resistor is used to represent the equivalent resistance of the flexible sensor; the capacitor is used to represent the equivalent capacitance of the combination of the flexible sensor and the eye solution to be measured; and the electrochemical impedance spectrum measurement region is used to collect the changes of the first resistor, the second resistor and the capacitor to obtain the electrochemical impedance spectrum representing eye physiological data.

2. The contact lens of claim 1, wherein, The flexible sensor further comprises: a conductive region and a communication region; the conductive region is used to make both ends of the electrochemical impedance spectrum measurement region conductive; the communication region is used to realize communication with the electrochemical impedance spectrum analysis module.

3. The contact lens of claim 2, wherein, The conductive region is obtained by patterning the conductive material through processes such as evaporation, sputtering and inkjet.

4. The contact lens of claim 2, wherein, The communication region comprises: an electrode; the electrode is connected with the electrochemical impedance spectrum analysis module through an ultrathin wire with biological compatibility and realizes communication.

5. The contact lens of claim 2, wherein, The communication region comprises: a first coil, which is wound on the contact lens body and connected with the flexible sensor, and realizes wireless communication through coupling induction with a second coil in the electrochemical impedance spectrum analysis module.

6. The contact lens of claim 1, wherein, The electrochemical impedance spectrum analysis module is attached to the skin around the eye.

7. The contact lens of claim 1, wherein, The electrochemical impedance spectrum analysis module comprises: a frequency generator, an analog-to-digital converter, a central processing unit, a wireless transmission module, a memory and an upper computer module; the frequency generator is used to provide the flexible sensor with a scanning frequency of the electrochemical impedance spectrum; the analog-to-digital converter is used to convert the analog signal of the electrochemical impedance collected by the flexible sensor into a digital signal of the electrochemical impedance spectrum; the central processing unit is used to send control instructions to the frequency generator, the analog-to-digital converter, the memory and the wireless transmission module, which are used to control the working states of the modules; the memory is used to store the digital signal of the electrochemical impedance spectrum; the wireless transmission module is used to wirelessly transmit the digital signal of the electrochemical impedance spectrum to the upper computer module; the upper computer module is used to calculate the electrochemical impedance spectrum parameters representing the health status of the eye according to the digital signal of the electrochemical impedance spectrum, and determine the electrochemical impedance spectrum curve representing the health status of the eye according to the parameters, and display the curve.

8. The contact lens of claim 5, wherein, The electrochemical impedance spectrum analysis module further comprises: a second coil, which is used to couple with the first coil in the flexible sensor when the flexible sensor and the electrochemical impedance spectrum analysis module are in wireless communication.

9. The contact lens of claim 1, wherein, Also included are: The flexible sensor is modified with a sensitive film for detecting a specific indicator.

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