Control method and device for radiotherapy device, terminal and storage medium

Through the multi-isocenter dynamic control method, the coordination of isocenters and auxiliary centers is utilized to control the movement of the treatment bed and rotating gantry, forming a radiation field shape that adapts to the target area contour, solving the problem of excessive radiation dose to surrounding tissues during radiotherapy, and achieving improved target area coverage and uniformity.

CN114558252BActive Publication Date: 2025-10-17THE FOURTH HOSPITAL OF HEBEI MEDICAL UNIVERSITY (HEBEI CANCER HOSPITAL)
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Patent Information

Application Number
CN202210205016.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-03-02
Publication Date
2025-10-17
Estimated Expiration
2042-03-02

AI Technical Summary

Technical Problem

When treating superficial tumors, existing radiotherapy technology tends to increase the radiation dose to surrounding sensitive tissues, causing damage to surrounding healthy tissues.

Method used

A multi-isocenter dynamic control method is adopted to obtain the initial image of the patient's tissue, determine the isocenter, first auxiliary center and second auxiliary center, control the movement of the treatment bed and rotating gantry, and use a multi-leaf collimator to form different field shapes to cover the target area and reduce exposure to surrounding tissues.

Benefits of technology

Improve target coverage and uniformity, reduce irradiation to surrounding sensitive tissues, and improve treatment accuracy and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application provides a control method and device for a radiotherapy device, a terminal and a storage medium. The method comprises: the radiotherapy device comprises a rotating gantry and a multi-leaf collimator (MLC) arranged on the rotating gantry; the control method comprises: acquiring an initial image of a patient tissue and determining a center of isocenter for a planning target volume (PTV); determining a first auxiliary center and a second auxiliary center according to the center of isocenter and the area of the PTV; controlling the position movement of the rotating gantry and the MLC according to the center of isocenter, the first auxiliary center and the second auxiliary center, and irradiating the PTV to form different field shapes; wherein the irradiation area according to the center of isocenter, the first auxiliary center and the second auxiliary center covers the area of the PTV. The application dynamically controls the position movement of the rotating gantry and the MLC based on multiple centers of isocenter to perform supplementary irradiation on the PTV, so that the target area coverage and uniformity can be improved, and the irradiation on the sensitive tissue around the PTV can be reduced.
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Description

TECHNICAL FIELD

[0001] The present application relates to the field of radiotherapy, and in particular to a control method and device for a radiotherapy device, a terminal and a storage medium. BACKGROUND

[0002] At present, static or rotating intensity modulated radiotherapy technology is implemented by using high-energy photon beams, and great progress has been made in the treatment of deep tumor cancer. However, the treatment technology for superficial tumors has been slow, and the treatment of breast cancer patients still mainly relies on photon beam irradiation of the transverse cut line, supplemented by electron beam irradiation. For skin surface sarcoma, transverse rotation irradiation control treatment is often implemented by surface positioning radionuclide or unmodulated electron beam, or a 3D printing technology is used to make an individualized precise radiotherapy head film for scalp tumor patients to increase the build-up to improve the epidermal dose. However, there is a problem of increasing the irradiation dose of the surrounding sensitive tissues. SUMMARY

[0003] The embodiments of the present application provide a control method and device for a radiotherapy device, a terminal and a storage medium to solve the problem of increasing the irradiation dose of the surrounding sensitive tissues in the prior art.

[0004] In a first aspect, the embodiments of the present application provide a control method for a radiotherapy device, the radiotherapy device comprising a rotating gantry, a treatment bed and a multi-leaf collimator (MLC) arranged on the rotating gantry; the control method comprising:

[0005] obtaining an initial image of a patient tissue and determining a center of isocenter for a planning target volume (PTV);

[0006] determining a first auxiliary center and a second auxiliary center according to the isocenter and the area of the PTV;

[0007] controlling the treatment bed to move and the rotating gantry to rotate according to the isocenter, the first auxiliary center and the second auxiliary center, and controlling the position of the MLC to move according to the shape of the PTV and irradiating the PTV to form different field shapes; wherein the area irradiated according to the isocenter, the first auxiliary center and the second auxiliary center covers the area of the PTV.

[0008] In a possible implementation manner, the controlling the treatment bed to move and the rotating gantry to rotate according to the isocenter, the first auxiliary center and the second auxiliary center comprises:

[0009] determining corresponding treatment couch positions, tangent line start angles and rotation angles according to the isocenter, the first secondary center and the second secondary center;

[0010] controlling the treatment couch to move according to the isocenter corresponding treatment couch position and controlling the rotating gantry to rotate according to the isocenter corresponding tangent line start angle and rotation angle;

[0011] controlling the treatment couch to move to the first secondary center corresponding treatment couch position and controlling the rotating gantry to rotate according to the first secondary center corresponding tangent line start angle and rotation angle;

[0012] controlling the treatment couch to move to the second secondary center corresponding treatment couch position and controlling the rotating gantry to rotate according to the second secondary center corresponding tangent line start angle and rotation angle.

[0013] In a possible implementation, the tangent line start angle and rotation angle are determined, comprising:

[0014] respectively taking the isocenter, the first secondary center and the second secondary center as a field isocenter, determining an intermediate tangent line as a start angle;

[0015] respectively taking the isocenter, the first secondary center and the second secondary center as a field isocenter, and determining an inside tangent angle, an inside tangent line start angle, an outside tangent line start angle and a rotation angle according to a thickness of a PTV and a beam entrance of a corresponding radiotherapy device;

[0016] The outside tangent line start angle is a conjugate reciprocal of the inside tangent line start angle.

[0017] In a possible implementation, the inside tangent angle, the inside tangent line start angle and the rotation angle satisfy the following relationship:

[0018]

[0019]

[0020]

[0021]

[0022]

[0023] Wherein, θ is an inner tangent angle, i.e. an included angle of a tangent line corresponding to a maximum thickness of the PTV; θ2 is an inner tangent starting angle; θ1 is a rotation angle; x1 is a tangent maximum depth of the PTV, i.e. half of the maximum thickness of the PTV; x2 is a distance from a field center to a point of intersection of the PTV and an inner horizontal tangent line; and x3 is a distance from the beam entrance to the point of intersection of the PTV and the inner horizontal tangent line.

[0024] In a possible implementation, the rotation rate of the rotating gantry and the irradiation dose rate are constant.

[0025] In a possible implementation, the rotation rate of the rotating gantry and the irradiation dose rate are adjustable.

[0026] In a possible implementation, the MLC rotation is controlled in a dynamic sliding manner or a sliding window manner.

[0027] In a possible implementation, the acquiring of the initial image of the patient tissue and the determination of the isocenter according to the PTV positioning comprises:

[0028] determining a tumor region shape according to the initial image of the patient tissue;

[0029] determining the PTV according to the tumor region shape and a preset optimization distance, and determining the isocenter according to the position of the PTV.

[0030] In a second aspect, an embodiment of the present application provides a control device for a radiotherapy device, the radiotherapy device comprising: a rotating gantry, a treatment bed and a multi-leaf collimator (MLC) arranged on the rotating gantry; and the control device comprising:

[0031] an acquiring module configured to acquire an initial image of patient tissue and determine an isocenter according to PTV positioning;

[0032] an assisting module configured to determine a first auxiliary center and a second auxiliary center according to the isocenter and an area of the PTV;

[0033] a control module configured to control movement of the treatment bed and rotation of the rotating gantry according to the isocenter, the first auxiliary center and the second auxiliary center, and control movement of the MLC according to the PTV shape to irradiate the PTV to form different field shapes; wherein an area irradiated according to the isocenter, the first auxiliary center and the second auxiliary center covers an area of the PTV.

[0034] In a third aspect, an embodiment of the present application provides a terminal, comprising a memory, a processor and a computer program stored in the memory and executable on the processor, and the processor implements steps of the method in the first aspect or any possible implementation manner of the first aspect when executing the computer program.

[0035] In a fourth aspect, an embodiment of the present application provides a computer readable storage medium, which stores a computer program. The computer program is executed by a processor to implement the steps of the method in the first aspect or any possible implementation manner of the first aspect.

[0036] The embodiment of the present application provides a control method and device for a radiotherapy device, a terminal and a storage medium. In the control process, an initial image of a patient tissue is acquired, and a center is determined by positioning a PTV. A first auxiliary center and a second auxiliary center are determined according to the center, the area and the shape of the PTV, so that a first auxiliary center and a second auxiliary center are used to supplement a field determined based on the center. The treatment bed is controlled to move and the rotating gantry is controlled to rotate according to the center, the first auxiliary center and the second auxiliary center, and the MLC is controlled to move to form different field shapes according to the shape of the PTV, so as to adapt to the profile of the PTV to perform tangential rotation radiotherapy on the tumor. The area irradiated according to the center, the first auxiliary center and the second auxiliary center covers the area of the PTV. The embodiment of the present application controls the position of the treatment bed, controls the rotation of the rotating gantry and optimizes the MLC sub-field based on the multiple centers, so as to supplement the PTV, which can improve the target area coverage and uniformity, and reduce the irradiation on the sensitive tissue around the PTV. BRIEF DESCRIPTION OF DRAWINGS

[0037] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiments or prior art description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0038] Figure 1 is the implementation flowchart of the control method for the radiotherapy device provided by the embodiment of the present application;

[0039] Figure 2a is the field multi-center control arc design schematic diagram of the scalp sarcoma patient shown by an embodiment of the present application;

[0040] Figure 2b is Figure 2a is the field distribution diagram of the scalp sarcoma patient shown in the embodiment of the present application, which is based on the field control arc design schematic diagram of the second auxiliary center;

[0041] Figure 3 is the field single-center control arc design schematic diagram of the scalp sarcoma patient shown by an embodiment of the present application;

[0042] Figure 4is a two-dimensional dose distribution (transverse section) CT diagram of a target region of a scalp sarcoma patient, as shown in an embodiment of the present application;

[0043] Figure 5a is a single isocenter control arc design diagram of a breast cancer patient's field, as shown in an embodiment of the present application;

[0044] Figure 5b is a multi-isocenter control arc design diagram of a breast cancer patient's field, as shown in an embodiment of the present application;

[0045] Figure 6 is a two-dimensional dose distribution (transverse section) CT diagram of a target region of a breast cancer patient, as shown in an embodiment of the present application;

[0046] Figure 7a is a dose volume histogram (DVH) of single isocenter and multi-isocenter irradiation technology of a scalp sarcoma patient, as shown in an embodiment of the present application;

[0047] Figure 7b is a DVH of single isocenter and multi-isocenter irradiation technology of a breast cancer patient, as shown in an embodiment of the present application;

[0048] Figure 8 is a structural schematic diagram of a control device for a radiotherapy device, provided by an embodiment of the present application;

[0049] Figure 9 is a schematic diagram of a terminal, provided by an embodiment of the present application. DETAILED DESCRIPTION

[0050] In the following description, specific details are set forth in order to provide a thorough understanding of embodiments of the application. However, persons of ordinary skill in the art will readily recognize that embodiments of the application can be practiced without these specific details. In other instances, well-known structures, devices, circuits, and processes have not been described in detail so as not to unnecessarily obscure aspects of the application.

[0051] Intensity modulated ARC therapy (IMAT) is the combination of intensity modulated radiotherapy (IMRT) and arc therapy, which has the advantages of both intensity modulated radiotherapy and arc therapy. The present application mainly proposes a multi-isocenter tangential IMAT irradiation technology for superficial tumors on the basis of the clinical application of conventional linear accelerator IMAT. The method uses one or more rotation angle modulated tangential photon beams to provide accurate coverage of the superficial target tumor volume through multi-isocenter irradiation, while significantly reducing the irradiation dose of the surrounding sensitive tissues.

[0052] In order to make the objects, technical solutions and advantages of the present application clearer, the following will be described with specific embodiments in conjunction with the accompanying drawings.

[0053] Figure 1 is the implementation flowchart of the control method for the radiotherapy device provided by the embodiment of the present application.

[0054] As shown in Figure 1 , the method comprises the following steps:

[0055] S101, acquiring an initial image of a patient tissue and determining an isocenter for a PTV.

[0056] The scheme provided by the present application is mainly for the treatment of superficial tumors, and is commonly used for the treatment of patients with scalp sarcoma and breast cancer. The initial image of the patient tissue is the Digital Imaging and Communications in Medicine (DICOM) data of the lesion site and the surrounding sensitive tissues. The PTV is determined based on the target region, and the volume of the PTV is greater than that of the target region. The target region is the tissue where the lesion occurs. For example, when treating a patient with scalp sarcoma, the target region is the scalp sarcoma, and the surrounding sensitive tissues include the spinal cord, the brain stem, the left and right optic nerves, and the left and right lenses. For breast cancer patients and retrograde treatment, the target region is the breast, and the surrounding sensitive tissues include lung tissue and the heart.

[0057] S102, determining a first auxiliary center and a second auxiliary center according to the isocenter, the area and shape of the PTV.

[0058] Due to the irregular shape of the lesion structure, based on the single-isocenter irradiation technology, a certain upper limit of the irradiation dose is used to meet the basic treatment needs, which will cause the surrounding sensitive tissues of the lesion structure to be affected by a larger dose. Determining the first auxiliary center and the second auxiliary center based on the isocenter and the area of the PTV can make the dose irradiation area more uniform, and can adapt to reduce the irradiation dose, thereby reducing the dose of the surrounding sensitive tissues of the lesion structure.

[0059] S103, controlling the treatment couch to move and the rotating gantry to rotate according to the isocenter, the first auxiliary center and the second auxiliary center, and controlling the MLC to move to form different field shapes according to the PTV shape. Wherein, the treatment couch is controlled to move in relative position according to the isocenter coordinate position and the relative coordinate positions of the first auxiliary center and the second auxiliary center. The treatment couch can be translated in up-down, left-right and front-back directions.

[0060] Wherein, the isocenter is the priority highest projection point, and the first auxiliary center and the second auxiliary center are the supplementary field projection points to complete the irradiation plan optimization. Compared with the single center scheme, the PTV can be projected from different angles. The present application mainly proposes the multi-isocenter tangent IMAT irradiation technology for superficial tumors on the basis of the conventional linear accelerator IMAT clinical application, can realize the automatic couch control and tangent rotation irradiation control of the radiotherapy device, improves the supplementary field irradiation from different angles, and improves the target area coverage and uniformity.

[0061] In the embodiment of the present application, the lead door fixed limit setting is selected during the irradiation plan optimization, so as to avoid forming a ray sub-field which is not perpendicular to the body surface during the optimization process. Therefore, the position adjustment of the lead door is not included in step S103.

[0062] In a possible implementation, the lead door follows the MLC leaf movement, and step S103 includes: controlling the positions of the treatment couch, the rotating gantry and the MLC to move and irradiating the PTV to form different field shapes according to the isocenter, the first auxiliary center and the second auxiliary center.

[0063] In the embodiment of the present application, the first auxiliary center and the second auxiliary center are determined according to the isocenter, the area and the shape of the PTV, so as to supplement the irradiation field determined based on the isocenter through the first auxiliary center and the second auxiliary center. The treatment couch is controlled to move and the rotating gantry is controlled to rotate according to the isocenter, the first auxiliary center and the second auxiliary center, and the MLC is controlled to move to form different field shapes according to the PTV shape, so as to adapt to the contour of the PTV and perform tangent rotation radiotherapy on the tumor. Wherein, the irradiation areas of the isocenter, the first auxiliary center and the second auxiliary center cover the area of the PTV. The embodiment of the present application controls the position of the treatment couch, controls the rotating gantry to rotate and supplements the PTV through the MLC sub-field optimization based on the multi-isocenter, can improve the target area coverage and uniformity, and reduce the irradiation on the sensitive tissues around the PTV.

[0064] In a possible implementation, step S103 controls the treatment couch to move and the rotating gantry to rotate according to the isocenter, the first auxiliary center and the second auxiliary center, including:

[0065] determining the corresponding treatment couch position, tangent starting angle and rotation angle according to the isocenter, the first auxiliary center and the second auxiliary center;

[0066] The movement of the treatment bed is controlled according to the position of the treatment bed corresponding to the isocenter, and the rotation of the rotating gantry is controlled according to the tangent starting angle and rotation angle corresponding to the isocenter;

[0067] Controlling the treatment bed to move to the treatment bed position corresponding to the first auxiliary center, and controlling the rotation of the rotating frame according to the tangent starting angle and rotation angle corresponding to the first auxiliary center;

[0068] The treatment bed is controlled to move to the treatment bed position corresponding to the second auxiliary center, and the rotating frame is controlled to rotate according to the tangent starting angle and rotation angle corresponding to the second auxiliary center.

[0069] The relative displacement of the treatment couch in the x, y, and z directions is determined according to the relative displacement corresponding to the first auxiliary center and the isocenter, and the treatment couch is controlled to move to the first auxiliary center.

[0070] The relative displacement of the treatment bed in the x, y, and z directions is determined according to the relative displacement corresponding to the second auxiliary center and the first auxiliary center, and the treatment bed is controlled to move to the second auxiliary center.

[0071] In one possible implementation, determining the tangent starting angle and the rotation angle includes:

[0072] The isocenter, first auxiliary center, and second auxiliary center are used as the isocenter of the radiation field, and the medial tangential angle, medial tangent starting angle, lateral tangent starting angle, and rotation angle are determined according to the thickness of the PTV and the corresponding beam entrance.

[0073] The starting angle of the outer tangent is the conjugate reciprocal of the starting angle of the inner tangent.

[0074] In one possible implementation, Figure 2a and 2b The schematic diagram of the tangent starting angle and rotation angle corresponding to the isocenter is shown as an example. The inner tangent starting angle and the inner tangent angle satisfy the following relationship:

[0075]

[0076]

[0077]

[0078]

[0079]

[0080] Wherein, θ is the medial tangential angle, i.e., the angle of the tangent corresponding to the maximum thickness of the PTV; θ2 is the starting angle of the medial tangent; θ1 is the rotation angle; x1 is the maximum tangential depth of the PTV, i.e., half of the maximum thickness of the PTV; x2 is the distance from the isocenter of the field to the intersection of the PTV and the medial horizontal tangent; and x3 is the distance from the beam entrance to the intersection of the PTV and the medial horizontal tangent.

[0081] like Figure 2a The radiation field distribution diagram of a patient with scalp sarcoma is shown. Figure 2b for Figure 2a The radiation field distribution diagram for patients with scalp sarcoma shown is based on the schematic diagram of the radiation field control arc design of the second auxiliary center. Point A is the beam entrance, POI_3 is the radiation field center, CD corresponds to the maximum thickness of the PTV, that is, the maximum tissue thickness of the tumor target area, POI_3 is at the center of CD, and point D is the intersection of the PTV and the medial horizontal tangent.

[0082] for Figure 2a The radiation field distribution diagram of the scalp sarcoma patient shown in the figure takes the angle closest to the brain tissue as the starting angle of the tangent line. Figure 2b As shown in the figure, it can be seen intuitively that θ2 is determined as the starting angle of the tangent, that is:

[0083]

[0084] In a possible implementation, the rotation rate and irradiation dose rate of the rotating gantry are kept constant, ensuring that the radiotherapy device can evenly project radiation to the PTV and surrounding sensitive tissues, thereby achieving dose optimization.

[0085] In one possible implementation, the rotation rate and irradiation dose rate of the rotating gantry are adjustable.

[0086] In a possible implementation, a dynamic sliding method or a sliding window method is used to control the MLC rotation.

[0087] During the specific implementation process, in step S103, the treatment couch position is adjusted based on the isocenter, first auxiliary center, and second auxiliary center based on the multi-isocenter IMAT plan. Once the couch position stabilizes, the gantry is controlled to rotate, and the MLC and jaws are controlled to perform rotational irradiation around the PTV to be irradiated. Specifically, the MLC is tangentially slid throughout the rotation process, achieving intensity modulation across the subfields to optimize the target dose.

[0088] In a possible implementation, step S101 of acquiring an initial image of the patient's tissue and locating the PTV to determine the isocenter includes:

[0089] determining a tumor region shape based on an initial image of the patient's tissue;

[0090] The PTV is determined according to the shape of the tumor region and the preset optimization distance, and the isocenter is determined according to the position of the PTV.

[0091] That is, as shown in the treatment of a scalp sarcoma patient, in order to avoid the influence of brain tissue and other tissues affected by respiratory motion from being missing from the field, the edge of the target region is optimized with an edge of 2 cm beyond the scalp in air during optimization. Figure 2a

[0092] Figure 3 is a field distribution diagram of a scalp sarcoma patient according to an embodiment of the present application. Compared with the prior art, Figure 2a As shown in Figure 3 The field arc design of the single-isocenter IMAT plan is: from θ a1 counterclockwise rotation to θ a2 , the rotation angle is θ a1 + θ a2 , and the positioning point POI is used as the field isocenter for irradiation plan optimization.

[0093] As shown in Figure 2a The field design of the multi-isocenter IMAT plan is: on three isocenters, tangential irradiation is performed according to the shape of the PTV target region respectively: the field Arc1 takes the isocenter point POI_1 as the field isocenter, rotates counterclockwise from θ b1 to θ b2 , the tangential rotation angle is θ b2 - θ b1 ; the field Arc2 takes the isocenter point POI_2 as the field isocenter, rotates counterclockwise from θ b3 to θ b4 , the tangential rotation angle is 360°-( θ b4 - θ b3 ); the field Arc3 takes the isocenter point POI_3 as the field isocenter, rotates counterclockwise from θ b5 to θ b6 , the tangential rotation angle is 360°-( θ b5 - θ b6 ). During irradiation plan optimization, the lead door fixed limit setting is selected to avoid forming a ray sub-field that is not perpendicular to the body surface during optimization.

[0094] ​Based on the above control process, the MLC is controlled to make dynamic isocenter motion, in fact, a limited number of arcs are used in the treatment planning system, and each half rotation angle has a unique isocenter along the tangent trajectory of the field. In the optimization process, the optimal solution for the MLC position is found, and the tangent processing is performed at each predetermined beam angle, and the sub-field that does not meet the criterion is removed. Through the above setting, the IMAT plan lead door can effectively rotate with the rotating gantry, implement rotating irradiation around the volume to be irradiated, and adjust the sub-field in the tangent direction through sliding MLC to complete intensity modulation during the entire rotation process, so as to realize target dose optimization.

[0095] In one possible implementation, an asymmetric lead door mode is selected, one side of the lead door is placed farther away from the half field or field to prevent the light beam from passing through the sensitive tissue, and the other side of the lead door irradiates the tumor tissue.

[0096] Figure 4 is a two-dimensional dose distribution (cross-sectional) CT diagram of a scalp sarcoma patient target area shown by a specific embodiment of the present application. Among them, Figure 4 The left side (a) shows the intensity modulation based on the single isocenter IMAT plan field arc design, Figure 4 The left side (b) shows the intensity modulation based on the multi-isocenter IMAT plan field design, as can be seen from the figure, the multi-isocenter IMAT plan field design can improve the conformality of the target dose distribution and the coverage of the target dose.

[0097] Figure 5a and Figure 5b is a field distribution diagram of a breast cancer patient shown by a specific embodiment of the present application. Among them, as Figure 5a , the single isocenter IMAT plan field design is: the field is rotated from θ c1 to θ c2 counterclockwise, the rotation angle is θ c2 -θ c1 .

[0098] As Figure 5b , the multi-isocenter IMAT plan field design, in the tangent field arrangement mode recommended by Munshi et al., makes tangent irradiation on two auxiliary centers according to the PTV: the field Arc1 takes the left auxiliary center point POI_1 as the field isocenter, and is rotated from θ d1 to θ d2 counterclockwise, the rotation angle is θ d2 -θ d1 ; the field Arc2 takes the right isocenter point POI_2 as the field isocenter, and is rotated from θ d3 to θ d4 counterclockwise, the rotation angle is θ d4 -θ d3 .

[0099] Figure 6 is a schematic diagram of a two-dimensional dose distribution (cross-sectional) CT of a target region of a breast cancer patient according to an embodiment of the present application. In the diagram, Figure 6 The left side (a) shows intensity modulation based on a single-isocenter IMAT plan field design, Figure 6 The left side (b) shows intensity modulation based on a multi-isocenter IMAT plan field design. As can be seen from the diagram, the multi-isocenter IMAT plan field design can improve the conformality of the dose distribution of the target region and the coverage of the dose of the target region (e.g. Figure 6 in the area identified by the dashed oval).

[0100] Figure 7a and 7b is a DVH of a single-isocenter IMAT and a multi-isocenter tangential arc IMAT irradiation technique for a scalp sarcoma patient according to an embodiment of the present application. Figure 7b is a DVH of a single-isocenter IMAT and a multi-isocenter tangential arc IMAT irradiation technique for a breast cancer patient according to an embodiment of the present application. In the diagram, the solid line represents the value corresponding to the single-isocenter IMAT irradiation technique, and the dashed line represents the value corresponding to the multi-isocenter tangential arc IMAT irradiation technique.

[0101] As can be seen from Figure 7a and Figure 7b , the multi-isocenter tangential arc technique can better protect the OAR than the single-isocenter IMAT plan, and meet the clinical requirements. For a multi-isocenter tangential arc IMAT irradiation technique for a scalp sarcoma patient, the dose received by the spinal cord, the brain stem, the left and right optic nerves, the left and right lenses, and the OAR can be significantly reduced under the premise of maintaining the same coverage rate of the target region. For a breast cancer patient plan, the low-dose irradiated area of the affected lung and the heart can be significantly reduced. Compared with the traditional single-isocenter IMAT plan, since the multi-isocenter tangential IMAT adopts the relative tangential and tangential arc planes with dynamic irradiation, the irradiation of the surrounding sensitive tissues can be reduced, and the skin build-up dose can be increased to some extent, thereby improving the target region dose and making the target region dose have a better dose distribution.

[0102] It should be understood that the size of the serial number of each step in the above embodiments does not mean the order of execution, and the execution order of each process should be determined according to its function and inherent logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.

[0103] The following is a device embodiment of the present application. For details not described in detail, reference can be made to the corresponding method embodiments described above.

[0104] Figure 8A structural diagram of a control device for a radiotherapy device provided by an embodiment of the present application is shown, only parts related to the embodiment of the present application are shown for the convenience of description, and details are as follows:

[0105] As shown in Figure 8 , the control device for the radiotherapy device comprises an acquisition module 801, an auxiliary module 802 and a control module 803.

[0106] The acquisition module 801 is configured to acquire an initial image of a patient tissue and determine a center of isocenter, PTV positioning, etc.

[0107] The auxiliary module 802 is configured to determine a first auxiliary center and a second auxiliary center according to the isocenter, the area and shape of the PTV.

[0108] The control module 803 is configured to control movement of a treatment bed and control rotation of a rotating gantry according to the isocenter, the first auxiliary center and the second auxiliary center, and control movement of an MLC to form different field shapes according to the shape of the PTV; wherein an area irradiated according to the isocenter, the first auxiliary center and the second auxiliary center covers the area of the PTV.

[0109] In the embodiment of the present application, the first auxiliary center and the second auxiliary center are determined according to the isocenter, the area and shape of the PTV, so as to supplement the irradiation field determined based on the isocenter by the first auxiliary center and the second auxiliary center. The movement of the treatment bed and the rotation of the rotating gantry are controlled according to the isocenter, the first auxiliary center and the second auxiliary center, and the movement of the MLC is controlled to form different field shapes according to the shape of the PTV, so as to adapt to the contour of the PTV to perform tangential rotation radiotherapy on the tumor. The area irradiated according to the isocenter, the first auxiliary center and the second auxiliary center covers the area of the PTV. The embodiment of the present application dynamically controls the position of the treatment bed, controls the rotation of the rotating gantry and optimizes the MLC sub-field based on multiple isocenters to supplement the PTV, which can improve the target area coverage and uniformity, and reduce the irradiation on the sensitive tissue around the PTV.

[0110] Figure 9 is a schematic diagram of a terminal provided by an embodiment of the present application. As shown in Figure 9 , the terminal 9 of this embodiment comprises a processor 90, a memory 91, and a computer program 92 stored in the memory 91 and executable on the processor 90. The processor 90 implements the steps in each of the above-mentioned control methods for a radiotherapy device embodiment when executing the computer program 92, such as Figure 1 steps S101 to S103. Alternatively, the processor 90 implements the functions of each module / unit in each of the above-mentioned device embodiments when executing the computer program 92, such as Figure 8 the functions of the modules 801 to 803.

[0111] By way of example, the computer program 92 can be segmented into one or more modules / units that are stored in the memory 91 and executed by the processor 90 to accomplish the present application. The one or more modules / units can be a series of computer program instruction segments that accomplish a specific function, which are used to describe the execution process of the computer program 92 in the terminal 9. For example, the computer program 92 can be segmented into Figure 8 the functions of the illustrated modules 801-803.

[0112] The terminal 9 can be a desktop computer, a notebook, a palm computer, a cloud server, and the like. The terminal 9 can include, but is not limited to, the processor 90 and the memory 91. Those skilled in the art can understand that the terminal 9 can include more or fewer components than those shown, or combine some components, or include different components, for example, the terminal can also include an input / output device, a network access device, a bus, and the like. Figure 9 The terminal 9 shown is merely an example and does not constitute a limitation on the terminal 9, and can include more or fewer components than those shown, or combine some components, or include different components, for example, the terminal can also include an input / output device, a network access device, a bus, and the like.

[0113] The processor 90 can be a central processing unit (CPU), and can also be other general-purpose processors, a digital signal processor (DSP), an application specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, or the like. The general-purpose processor can be a microprocessor or the processor can also be any conventional processor.

[0114] The memory 91 can be an internal storage unit of the terminal 9, such as a hard disk or a memory of the terminal 9. The memory 91 can also be an external storage device of the terminal 9, such as a plug-in hard disk, a smart media card (SMC), a secure digital (SD) card, a flash card, and the like. Further, the memory 91 can include both an internal storage unit and an external storage device of the terminal 9. The memory 91 is used to store the computer program and other programs and data required by the terminal. The memory 91 can also be used to temporarily store data that has been output or will be output.

[0115] Those skilled in the art can clearly understand that, for the convenience and brevity of description, only the above-mentioned division of each functional unit and module is exemplified, and in actual application, the above-mentioned functions can be completed by different functional units and modules according to needs, that is, the internal structure of the device is divided into different functional units or modules to complete all or part of the functions described above. Each functional unit and module in the embodiment can be integrated in one processing unit, or each unit can be physically present separately, or two or more units can be integrated in one unit. The above-mentioned integrated unit can be realized in the form of hardware or software. In addition, the specific names of each functional unit and module are only for the convenience of mutual distinction, and do not limit the protection scope of the present application. The specific working process of the units and modules in the above system can refer to the corresponding process in the foregoing method embodiments, which will not be described here.

[0116] In the above embodiments, the description of each embodiment has its own emphasis, and the parts not described or recorded in detail in a certain embodiment can be referred to the related description of other embodiments.

[0117] Those of ordinary skill in the art can realize that the units and algorithm steps of each example described in combination with the embodiments disclosed herein can be realized in electronic hardware or a combination of computer software and electronic hardware. Whether the functions are executed in hardware or software depends on the specific application and design constraints of the technical solution. A person skilled in the art can use different methods to implement the described functions for each specific application, but such implementation should not be considered beyond the scope of the present application.

[0118] In the embodiments provided by the present application, it should be understood that the disclosed apparatus / terminal and method can be implemented by other ways. For example, the above-mentioned apparatus / terminal embodiments are only schematic, and the division of the modules or units is only a logical function division, and there can be another division way in actual implementation, for example, multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. In addition, the displayed or discussed mutual coupling or direct coupling or communication connection can be indirect coupling or communication connection through some interface, device or unit, and can be electrical, mechanical or other forms.

[0119] The units described as separate components can or can not be physically separated, and the components shown as units can or can not be physical units, that is, they can be located in one place, or can be distributed on multiple network units. Part or all of the units can be selected according to actual needs to achieve the purpose of the embodiment.

[0120] In addition, each function unit in each embodiment of the present application can be integrated in one processing unit, or each unit can be physically present separately, or two or more units can be integrated in one unit. The integrated unit can be realized in the form of hardware or in the form of a software function unit.

[0121] The integrated module / unit, if realized in the form of a software function unit and sold or used as an independent product, can be stored in a computer-readable storage medium. Based on this understanding, all or part of the processes in the above-mentioned embodiment methods can also be completed by a computer program instructing related hardware, and the computer program can be stored in a computer-readable storage medium. The computer program can implement the steps of each of the above-mentioned control method embodiments for a radiotherapy device when executed by a processor. The computer program includes computer program code, which can be in the form of source code, object code, an executable file, or some intermediate form, etc. The computer-readable medium can include any entity or device capable of carrying the computer program code, a recording medium, a U disk, a mobile hard disk, a magnetic disk, an optical disk, a computer memory, a read-only memory (ROM), a random access memory (RAM), an electrical carrier signal, a telecommunication signal, and a software distribution medium, etc. It should be noted that the contents included in the computer-readable medium can be appropriately increased or decreased according to the requirements of legislation and patent practice in the jurisdiction, for example, in some jurisdictions, according to legislation and patent practice, the computer-readable medium does not include electrical carrier signals and telecommunication signals.

[0122] The above-described embodiments are only used to illustrate the technical solutions of the present application, rather than limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present application, and should be included in the protection scope of the present application.

Claims

1. A control device for a radiotherapy device, characterized in that: The radiotherapy device comprises: a rotating gantry, a treatment bed and a multi-leaf collimator MLC arranged on the rotating gantry; the control device comprises: An acquisition module is used to obtain an initial image of the patient's tissue and locate the PTV to determine the isocenter; an auxiliary module, configured to determine a first auxiliary center and a second auxiliary center according to the isocenter and the area and shape of the PTV; wherein the isocenter is used as the projection point with the highest priority, and the first auxiliary center and the second auxiliary center are used as fill-field projection points; a control module, configured to control the movement of the treatment couch and the rotation of the rotating gantry based on the isocenter, the first auxiliary center, and the second auxiliary center, and to control the movement of the MLC to form different radiation field shapes based on the shape of the PTV; wherein the area irradiated based on the isocenter, the first auxiliary center, and the second auxiliary center covers the area of ​​the PTV; wherein the corresponding treatment couch position, tangent starting angle, and rotation angle are determined based on the isocenter, the first auxiliary center, and the second auxiliary center, and the movement of the treatment couch and the rotation of the rotating gantry are controlled; Wherein, when the control module controls the movement of the treatment couch and the rotation of the rotating gantry according to the isocenter, the first auxiliary center, and the second auxiliary center, it is specifically used to: Controlling the movement of the treatment couch according to the position of the treatment couch corresponding to the isocenter, and controlling the rotation of the rotating gantry according to the tangent starting angle and the rotation angle corresponding to the isocenter; Controlling the treatment couch to move to a treatment couch position corresponding to the first auxiliary center, and controlling the rotating gantry to rotate according to a tangent starting angle and a rotation angle corresponding to the first auxiliary center; Controlling the treatment couch to move to a treatment couch position corresponding to the second auxiliary center, and controlling the rotating gantry to rotate according to a tangent starting angle and a rotation angle corresponding to the second auxiliary center; Wherein, when the control module determines the corresponding treatment bed position, tangent starting angle and rotation angle according to the isocenter, the first auxiliary center and the second auxiliary center, it is specifically used to: The isocenter, the first auxiliary center, and the second auxiliary center are respectively used as the isocenter of the radiation field, and the inner tangential angle, the inner tangential starting angle, the outer tangential starting angle, and the rotation angle are determined according to the thickness of the PTV and the corresponding beam entrance; The outer tangent starting angle is the conjugate reciprocal of the inner tangent starting angle.

2. The control device according to claim 1, characterized in that The inner tangent angle, the inner tangent starting angle and the rotation angle satisfy the following relationship: in, is the medial tangential angle, that is, the angle of the tangent line corresponding to the maximum thickness of the PTV; is the starting angle of the inner tangent; is the rotation angle; The maximum tangential depth of the PTV, that is, half of the maximum thickness of the PTV; The distance from the isocenter of the radiation field to the intersection of the PTV and the medial horizontal tangent; is the distance from the beam entrance to the point where the PTV intersects the medial horizontal tangent.

3. The control device according to claim 1 or 2, characterized in that: The acquisition module is specifically used to: determining a shape of a tumor region based on an initial image of the patient tissue; The PTV is determined according to the shape of the tumor region and a preset optimized distance, and the isocenter is determined according to the position of the PTV.

4. The control device according to claim 3, characterized in that The rotation rate and irradiation dose rate of the rotating gantry are constant or adjustable.

5. The control device according to claim 3, characterized in that The MLC rotation is controlled by a dynamic sliding method or a sliding window method.

Citation Information

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